AutismKB 2.0

Annotation Detail for LMNA


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LMNA ( CDCD1,CDDC,CMD1A,CMT2B1,EMD2,FPL,FPLD,HGPS,IDC,LDP1,LFP,LGMD1B,LMN1,LMNC,LMNL1,PRO1 )
Gene Full Name: lamin A/C
Band: 1q22
Quick LinksEntrez ID:4000; OMIM: 150330; Uniprot ID:LMNA_HUMAN; ENSEMBL ID: ENSG00000160789; HGNC ID: 6636
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05410Hypertrophic cardiomyopathy (HCM)
hsa05412Arrhythmogenic right ventricular cardiomyopathy (ARVC)
hsa05414Dilated cardiomyopathy
Pathway IDPathway Name
Diabetes pathways
Apoptosis
Pathway IDPathway Name
200148Caspase cascade in apoptosis
Pathway IDPathway Name
P00020FAS signaling pathway
Pathway IDPathway Name
500273Breakdown of the nuclear lamina
Related Diseases/Disorders Top
Desease IDDesease Name
Circulatory system diseases
Other genetic disorders
H00420Familial partial lipodystrophy
Cardiac diseases
H00294Dilated cardiomyopathy (DCM)
Genetic disorders
Desease IDDesease Name
1726Charcot-Marie-Tooth disease
1775Muscular atrophy
1787Heart disease
1791Neuropathy
1802Cockayne syndrome
1970Virus disease
2053Colon cancer
2115Muscular dystrophies
2197Metabolism disease
2238Lipodystrophy
2241Infertility
2259Hereditary disease
Desease Name
CARDIOVASCULAR
cardiomyopathy
leptin
dyslipidemia and insulin resistance
nephropathy in other diseases
RENAL
METABOLIC
obesity
insulin
cerebrovascular disease
diabetes, type 2
adipocyte size, large subcutaneous abdominal
No data
Desease Name
Charcot-Marie-Tooth disease, type 2B1
Restrictive dermopathy, lethal
Mandibuloacral dysplasia
Cardiomyopathy, dilated, 1A
Emery-Dreifuss muscular dystrophy, AD
Lipodystrophy, familial partial
Emery-Dreifuss muscular dystrophy, AR
Hutchinson-Gilford progeria
Muscular dystrophy, limb-girdle, type 1B
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C404910 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of LMNA mRNA]affects expression|affects reaction 19414516
C404910 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [FSHB protein affects the expression of LMNA mRNA]affects expression|affects reaction 19414516
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of LMNA mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of LMNA mRNAaffects expression 21346803
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of LMNA mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of LMNA mRNAaffects expression 17562736
D000242 Cyclic AMP 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of LMNA mRNA]affects expression|affects reaction 19414516
C430898 AGN 194204 AGN 194204 results in decreased expression of LMNA mRNAdecreases expression 16339527
D000643 Ammonium Chloride Ammonium Chloride affects the expression of LMNA mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of LMNA proteindecreases expression 20097212
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LMNA mRNAaffects cotreatment|decreases expression 20360939
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of LMNA mRNAaffects cotreatment|decreases expression 20360939
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of LMNA mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of LMNA mRNAincreases expression 17942748
16174780
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LMNA mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of LMNA mRNAincreases expression 16174780
C065180 fluvastatin fluvastatin results in decreased farnesylation of LMNA proteindecreases farnesylation 16996129
C096856 FTI 277 [FTI 277 co-treated with GGTI 2147] results in decreased farnesylation of LMNA proteinaffects cotreatment|decreases farnesylation 18587406
C096856 FTI 277 [FTI 277 co-treated with GGTI 2147] results in decreased geranoylation of LMNA proteinaffects cotreatment|decreases geranoylation 18587406
C056933 fumonisin B1 fumonisin B1 results in increased expression of LMNA mRNAincreases expression 16221962
C466792 GGTI 2147 [FTI 277 co-treated with GGTI 2147] results in decreased farnesylation of LMNA proteinaffects cotreatment|decreases farnesylation 18587406
C466792 GGTI 2147 [FTI 277 co-treated with GGTI 2147] results in decreased geranoylation of LMNA proteinaffects cotreatment|decreases geranoylation 18587406
C031927 hydroquinone hydroquinone affects the expression of LMNA proteinaffects expression 17181942
C510621 KCC 009 KCC 009 results in increased cleavage of LMNA proteinincreases cleavage 16170020
C115354 lonafarnib lonafarnib results in decreased farnesylation of LMNA proteindecreases farnesylation 16996129
D008628 Mercury Mercury results in decreased expression of LMNA mRNAdecreases expression 16823088
D015741 Metribolone Metribolone results in decreased expression of LMNA proteindecreases expression 17152098
D016685 Mitomycin LMNA protein affects the susceptibility to Mitomycinaffects response to substance 16217747
D009151 Mustard Gas FADD protein affects the reaction [Mustard Gas promotes the reaction [CASP6 protein results in increased cleavage of LMNA protein]]affects reaction|increases cleavage|increases reaction 12482751
D009151 Mustard Gas Mustard Gas results in increased cleavage of LMNA proteinincreases cleavage 12482751
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of LMNA mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of LMNA mRNAincreases expression 19482888
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of LMNA mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in decreased expression of LMNA mRNAdecreases expression 17426115
C006253 pirinixic acid pirinixic acid results in increased expression of LMNA mRNAincreases expression 16221962
D011794 Quercetin Quercetin results in decreased expression of LMNA proteindecreases expression 15221776
C037219 quinoline quinoline analog results in decreased expression of LMNA proteindecreases expression 18645022
C037219 quinoline quinoline analog results in increased expression of LMNA proteinincreases expression 18645022
C059514 resveratrol BAX protein promotes the reaction [resveratrol promotes the reaction [CASP6 protein results in increased cleavage of LMNA protein]]increases cleavage|increases reaction 16518869
C059514 resveratrol resveratrol promotes the reaction [CASP6 protein results in increased cleavage of LMNA protein]increases cleavage|increases reaction 16518869
C059514 resveratrol resveratrol results in increased cleavage of LMNA proteinincreases cleavage 16518869
17007014
C059514 resveratrol TP53 protein promotes the reaction [resveratrol promotes the reaction [CASP6 protein results in increased cleavage of LMNA protein]]increases cleavage|increases reaction 16518869
D012643 Selenium Selenium results in increased expression of LMNA mRNAincreases expression 19244175
D013629 Tamoxifen Tamoxifen affects the expression of LMNA mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin LMNA protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]increases expression|increases reaction 12761348
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LMNA mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of LMNA mRNAincreases expression 16960034
17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of LMNA mRNAdecreases expression 11752688
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of LMNA proteindecreases expression 19201780
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of LMNA mRNAincreases expression 16960034
D014303 Trinitrotoluene Trinitrotoluene affects the expression of LMNA mRNAaffects expression 21346803
D014810 Vitamin E Vitamin E results in increased expression of LMNA mRNAincreases expression 19244175
C088658 zoledronic acid zoledronic acid results in decreased farnesylation of LMNA proteindecreases farnesylation 16996129
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.2014745880
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 17.597525203
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 17.596195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 17.5915322242 14514962 11752688
MESH:D000014 Abnormalities, Drug-Induced Trinitrotoluene 17.597525203
MESH:D000138 Acidosis Ammonium Chloride 3.2218287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6017505938
MESH:D058186 Acute Kidney Injury resveratrol 8.0716538975
MESH:D058186 Acute Kidney Injury zoledronic acid 8.0719715164
MESH:D055371 Acute Lung Injury pirinixic acid 2.8118653653
MESH:D000210 Acute-Phase Reaction zoledronic acid 5.1420200999
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 3.8720464547 20127859
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 3.8714692618
MESH:D000236 Adenoma Benzo(a)pyrene 10.056695378
MESH:D000236 Adenoma Diethylnitrosamine 10.0510737359 6695378
MESH:D000236 Adenoma resveratrol 10.0515688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 22.0519052882 16434500 19061943 17162532 17620307 18056438
MESH:D018248 Adenoma, Liver Cell Phenobarbital 22.0517620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 22.0516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 22.0516835633
MESH:D000544 Alzheimer Disease resveratrol 2.4916162502 16183991
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.6511748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.9417084956
MESH:D000799 Angioedema Acetaminophen 3.5010982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.7419183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1311256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.6615885639
MESH:D001169 Arthritis, Experimental resveratrol 6.6617115116
MESH:D001249 Asthma Mustard Gas 2.6110378619
MESH:D001260 Ataxia Telangiectasia Quercetin 4.6415336622
MESH:D050197 Atherosclerosis resveratrol 3.0717967414 16873680
MESH:D001321 Autistic Disorder Acetaminophen 2.1418445737
MESH:D001321 Autistic Disorder Mercury 2.1417497416
MESH:D001327 Autoimmune Diseases Mercury 9.9016634805
MESH:D001327 Autoimmune Diseases Quercetin 9.9019761891
MESH:D001768 Blister Mustard Gas 4.8219167455
MESH:D001778 Blood Coagulation Disorders pirinixic acid 7.7619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 7.7612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5515746008
MESH:D001859 Bone Neoplasms zoledronic acid 4.6416121404 16778634 11697798 15867366 17312309 19442620
MESH:D001862 Bone Resorption zoledronic acid 4.4018496637 11869084 16769263 18404659 8053405 15845617
MESH:D002545 Brain Ischemia resveratrol 3.9417600658
MESH:D001932 Brain Neoplasms KCC 009 5.4916170020
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 3.5320146248 17474063
MESH:D001943 Breast Neoplasms Diethylnitrosamine 3.5317474063
MESH:D001943 Breast Neoplasms Quercetin 3.5318628248
MESH:D001943 Breast Neoplasms resveratrol 3.5316393696 17651959 17534123
MESH:D001943 Breast Neoplasms Tamoxifen 3.5318425577 16202921 18815881 19115204 17440819 18629630 20390343 19103187 17261762 19011961 17049068 20135344 19487384 19189210 19066611 19142967 20005174 11161223 19288272 18855134 20065188 19155303 18997820 20544844 18821012 15565566 18984771 19084267 21152245 19189212 21138602 18351453 19221464 15668708 19410462 19059307 17242785 16273361 16873071 19244106 16818667 19289846 17893378 19200415 20859285
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.5320435547
MESH:D001943 Breast Neoplasms zoledronic acid 3.5316096432 18695136
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.8215286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.6317687719 10378619
MESH:D002105 Cadmium Poisoning Quercetin 5.2016962696
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.6016050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5316835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1719066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 18.6716705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 18.6716705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 18.673084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 18.6719383236 18788625 16681979 17173139 19519916 20514400 17428255 16288022 10737359 20214788 18691550 10672840 20512989 17978847 16698587 19539802 18665156 16830150 19418558 16569478 19107877 20727157 18393292 17055752 20084675 19171122 18785209 17761372 20935162 17138121 19335982 18506893 20101231 16935385 18494052 19208518 16540662 16328049 3581430 16502159 18978308 16878318 18971187 19919837 20007298 19701751 20432363 18210153 20524982 3084413 19822196 19394651 21159647 16807293 19052882 11831363 17162532 18056438 16779866
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 18.6717173139 6705139 20007298 1701930 20935162
MESH:D006528 Carcinoma, Hepatocellular Quercetin 18.6719519916 12508355
MESH:D006528 Carcinoma, Hepatocellular quinoline 18.67598648
MESH:D006528 Carcinoma, Hepatocellular resveratrol 18.6716227395 19321006
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 18.6716924424
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.2516675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 3.4219233551
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.6217234771
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 3.6918507039
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.3720419170
MESH:D002294 Carcinoma, Squamous Cell resveratrol 4.3716227395
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.3217572228
MESH:D006332 Cardiomegaly Quercetin 6.1719794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.1718670907 18850075 16120746
MESH:D002311 Cardiomyopathy, Dilated marker/mechanism 15996213
MESH:D002311 Cardiomyopathy, Dilated Mercury 3.3310334427
MESH:D002318 Cardiovascular Diseases resveratrol 3.2415458977
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 11.3114694615
MESH:D002386 Cataract Acetaminophen 11.3110977129
MESH:D002386 Cataract Trinitrotoluene 11.3115817613 14694615
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 5.926135515
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 5.927505956 17174075 21159647 2727394
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.924080065
MESH:C537990 Charcot-Marie-Tooth disease, Type 2B1 marker/mechanism
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.3819052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.3816835633
MESH:D002779 Cholestasis Ethinyl Estradiol 6.9115861022 17681005 11677210 17333356 16105132 16919318 17110522
MESH:D002779 Cholestasis pirinixic acid 6.9119176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.9615668235 15340226 12621046 8697196 16354765
MESH:D003092 Colitis resveratrol 8.5516474422
MESH:D003092 Colitis Selenium 8.5517936198
MESH:D003110 Colonic Neoplasms Quercetin 3.7517191121 11134977 19440933 19056647 17148506 16640504 15741050
MESH:D003110 Colonic Neoplasms resveratrol 3.7516338953
MESH:D015179 Colorectal Neoplasms Quercetin 2.6618852136 18095365
MESH:D015179 Colorectal Neoplasms resveratrol 2.6616550006
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 13.9615095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 13.9614669216 17141729
MESH:D000013 Congenital Abnormalities Trinitrotoluene 13.9615095906
MESH:D003327 Coronary Disease fluvastatin 8.1816142594
MESH:D003327 Coronary Disease resveratrol 8.1816507316
MESH:D019465 Craniofacial Abnormalities marker/mechanism 15726408
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.3710048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.3719769572
MESH:D003490 Cyanosis 2,4-dinitrotoluene 16.8818551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 16.8818551238
MESH:D003490 Cyanosis Trinitrotoluene 16.8818551238
MESH:D016757 Death, Sudden, Cardiac marker/mechanism 15996213
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0319031437
MESH:D017449 Dermatitis, Allergic Contact Mercury 3.4816823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2718249437
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 7.6519496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 7.6516873680
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 3.9120387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.9117107852
MESH:D003928 Diabetic Nephropathies resveratrol 8.1016286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.1019279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 23.7621346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 23.7621346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 23.7621346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 23.7611421492 19420014 10915739 11743745 16781746 11739529 19416960 12594235 16081117 17906064 14725611 12540782 14986274 18713872 11461765 19164858 17562736 15619225 16109766 12392966 19370779 12153990 11287661 14550746 19085960 10663392 15968718 10774834 16177239 11529661 12705907 2444490 11834606 19923254 18071297 16227642 17522070 16485898 12958197 19739265 16393943
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 23.7619107877
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 23.7616221962
MESH:D056486 Drug-Induced Liver Injury Selenium 23.7615131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 23.7620420201
MESH:D056486 Drug-Induced Liver Injury Trinitrotoluene 23.7621346803 18551238
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.7519426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5111462148
MESH:D004421 Dystonia Phenobarbital 3.691851702
MESH:C538011 Eales disease Vitamin E 4.369068938
MESH:D004487 Edema Mustard Gas 13.979260866 11428631 11428647 11402378
MESH:D004487 Edema pirinixic acid 13.9712083418
MESH:D004487 Edema resveratrol 13.978985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 13.9712711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.5615322242 16714409 18230668
OMIM:181350 EMERY-DREIFUSS MUSCULAR DYSTROPHY 2, AUTOSOMAL DOMINANT marker/mechanism
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 13.4912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 13.4917872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 13.4919031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 2.8220544844 17893378 16202921 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.739294722 10568697
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.5217923197
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.783659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.533922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.7120417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.266401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.927750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.683659116
MESH:D004890 Erythema Mustard Gas 4.829357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.7716302075
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 1.9216530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.7611564622
MESH:D005234 Fatty Liver Diethylnitrosamine 16.2621071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 16.2615345470
MESH:D005234 Fatty Liver pirinixic acid 16.2619236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 16.2619224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0316709447
MESH:D005264 Femoral Fractures zoledronic acid 5.4916234978
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1211858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1914745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.8419069698
MESH:D005355 Fibrosis Quercetin 7.6619474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 7.6620067830
MESH:D005532 Foot Deformities, Congenital marker/mechanism 15996213
MESH:D005756 Gastritis Acetaminophen 3.3316983495
MESH:D005909 Glioblastoma KCC 009 7.3716170020
MESH:D005909 Glioblastoma Quercetin 7.3719804834
MESH:D005910 Glioma Quercetin 2.9217643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2510696789
MESH:D006228 Hand Deformities, Congenital marker/mechanism 15996213
MESH:D006327 Heart Block marker/mechanism 15996213
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.0420471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.0410048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 10.0416080930
MESH:D006333 Heart Failure pirinixic acid 6.2520558911
MESH:D006333 Heart Failure Selenium 6.2517162251
MESH:C535852 Heart-hand syndrome, Slovenian type marker/mechanism
MESH:D006390 Hemangioendothelioma quinoline 5.56598648
MESH:D006394 Hemangiosarcoma quinoline 4.69598648
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0311000095
MESH:D006529 Hepatomegaly fumonisin B1 23.6116221962
MESH:D006529 Hepatomegaly Phenobarbital 23.6116109766
MESH:D006529 Hepatomegaly pirinixic acid 23.6116221962 19176532 19772884 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 23.6115340226 12621046 16120746
MESH:D006529 Hepatomegaly Trinitrotoluene 23.6115817613
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.5816490937 16863852
MESH:D006561 Herpes Simplex resveratrol 3.8416876885
MESH:D019584 Hot Flashes Vitamin E 3.6314716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.7016354765 8697196 18606429 15340226 16959395
MESH:D006930 Hyperalgesia Acetaminophen 7.1216870215
MESH:D006930 Hyperalgesia zoledronic acid 7.1216769263
MESH:D006934 Hypercalcemia zoledronic acid 4.7419622757 18089816
MESH:D006937 Hypercholesterolemia resveratrol 3.7017188708
MESH:D006943 Hyperglycemia pirinixic acid 8.2720558911
MESH:D006943 Hyperglycemia Quercetin 8.2711834736 18262572
MESH:D006949 Hyperlipidemias resveratrol 3.7216873680
MESH:D006973 Hypertension Quercetin 4.7718356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.7718850075 18670907
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.0117488730
MESH:D006996 Hypocalcemia zoledronic acid 5.8512669777
MESH:D007021 Hypospadias Ethinyl Estradiol 3.4816945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.3117600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1512013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.1417937319
MESH:D007248 Infertility, Male Trinitrotoluene 6.1412150543
MESH:D007249 Inflammation Diethylnitrosamine 13.9418785209
MESH:D007249 Inflammation Mustard Gas 13.9411402378 8975870 9357497 17524151 11428647 9260866 16001271 11428620 11428631
MESH:D007249 Inflammation resveratrol 13.9416366677
MESH:D007249 Inflammation Tamoxifen 13.9419457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 13.9412200463 12878042
MESH:D007251 Influenza, Human Quercetin 23.7816624496
MESH:D007251 Influenza, Human resveratrol 23.7816624496
MESH:D007251 Influenza, Human Selenium 23.7816624496
MESH:D007251 Influenza, Human Vitamin E 23.7816624496
MESH:D007333 Insulin Resistance pirinixic acid 2.4116306350
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.2910783313
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.0316580747
MESH:D007627 Keloid Quercetin 4.6217086741
MESH:D007674 Kidney Diseases Acetaminophen 16.9812587719 15629191
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 16.9815369732
MESH:D007674 Kidney Diseases Mercury 16.9817934191
MESH:D007674 Kidney Diseases Quercetin 16.9816962696
MESH:D007674 Kidney Diseases Vitamin E 16.9812488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.5816518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 10.8216705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 10.8216705839
MESH:D007680 Kidney Neoplasms Tamoxifen 10.8218625569
MESH:D007938 Leukemia Quercetin 2.9917468513
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 4.4718089816
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 7.3416766008
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 7.3416087638
MESH:D008064 Lipidoses Tamoxifen 2.9117567588 15342952
OMIM:151660 LIPODYSTROPHY, FAMILIAL PARTIAL, TYPE 2 marker/mechanism
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.0120032147 19638242 18522880 18407596 18665156
MESH:D008103 Liver Cirrhosis Phenobarbital 6.0121047994
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.2215474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 6.2212741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 6.2218564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.2212878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 6.2216169303
MESH:D008107 Liver Diseases Acetaminophen 5.9219460945 19784758 19014921 16610002 12969438 11587558 16611625 12587719
MESH:D008107 Liver Diseases Diethylnitrosamine 5.9217034775
MESH:D008107 Liver Diseases Phenobarbital 5.9219363144
MESH:D017114 Liver Failure, Acute Acetaminophen 2.9416871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 31.507678174
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 31.5021137059 20195826
MESH:D008113 Liver Neoplasms Diethylnitrosamine 31.5021071580 20452335 18978307 18977376 9163691 12771043 20118626 20137499 19833225 19812893 10737359 18648771 20501860 19254457 2422723 15175105 20492335 19690152 19551842 21278145 15885732 12112319 19642983 19294768 16942905 19638242 2862719 19499222 19427195 20101389 20434301 19996281 21167192 19255062 18754104 18644402 19850985 19426721 21047994 19073162 20405173 20583210 19090486 19256749
MESH:D008113 Liver Neoplasms Mitomycin 31.5015113037
MESH:D008113 Liver Neoplasms Phenobarbital 31.5019812893 19073162 8742319 15975961 21047994 19482888
MESH:D008113 Liver Neoplasms pirinixic acid 31.5020007298 15890375 16377806
MESH:D008113 Liver Neoplasms Quercetin 31.5018980244
MESH:D008113 Liver Neoplasms resveratrol 31.5019073162 19812893 19321006 20405173
MESH:D008113 Liver Neoplasms Tamoxifen 31.5016684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 31.5016984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 16.382876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 16.3817174075 16267830 18282651 18775883 21159647 18079962 19126423 19519916 19004024 19009564 17942915 19539802 3124819 18544905 9362446 18164116 18093689 16842330 17854601 18253720 18308698 2563599
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 16.382563599 17172636 6150874 1399818 18308698
MESH:D008114 Liver Neoplasms, Experimental Quercetin 16.3819519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 16.3812151625
MESH:D008171 Lung Diseases Mustard Gas 6.7918161513 18702808
MESH:D008171 Lung Diseases Vitamin E 6.7916863852
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 9.9620135361 18816296 20064080 20464547 6695378 18569708 18520028 17053015 20869020
MESH:D008175 Lung Neoplasms Diethylnitrosamine 9.9620970405 20512841 6695378 21163286
MESH:D008175 Lung Neoplasms Mustard Gas 9.963148597 8781369
MESH:D008175 Lung Neoplasms Quercetin 9.9616280456
MESH:D008175 Lung Neoplasms Tamoxifen 9.9618625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 9.9611884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 9.9611062179
MESH:D016393 Lymphoma, B-Cell resveratrol 3.9917088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.6014749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 8.8715688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 8.8719428831
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 12.5411606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental Selenium 12.5415318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 12.5414580682 11731420 19196723 19196722 16827153
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 12.5417312309
MESH:C535705 Mandibuloacral dysplasia with type A lipodystrophy marker/mechanism 12788894 19764019 17848409
MESH:D020149 Manganese Poisoning Tamoxifen 4.2019453300
MESH:D008545 Melanoma resveratrol 3.2317992120
MESH:D008545 Melanoma Tamoxifen 3.2312393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.8415990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2419513568
MESH:D008654 Mesothelioma Selenium 6.0715107826
MESH:D008654 Mesothelioma zoledronic acid 6.0716675582
MESH:D008659 Metabolic Diseases resveratrol 4.0717112576
MESH:D020326 Migraine without Aura Cyclic AMP 4.8311304026
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.9316381670
MESH:D009101 Multiple Myeloma fluvastatin 15.5016996129
MESH:D009101 Multiple Myeloma lonafarnib 15.5016996129
MESH:D009101 Multiple Myeloma resveratrol 15.5017935668 16490592 17164350 16267019 14749477 17049120
MESH:D009101 Multiple Myeloma zoledronic acid 15.5019621390 18089719 16996129
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.5317962980
MESH:D009135 Muscular Diseases pirinixic acid 3.1716239165
MESH:D049288 Muscular Dystrophies, Limb-Girdle marker/mechanism 12032588
MESH:D020389 Muscular Dystrophy, Emery-Dreifuss marker/mechanism 12032588
OMIM:159001 MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 1B marker/mechanism
MESH:D009203 Myocardial Infarction pirinixic acid 8.6619151258
MESH:D009203 Myocardial Infarction Quercetin 8.6619595682
MESH:D009203 Myocardial Infarction resveratrol 8.6616456233 16317513 17188708 17125593 16525036 17015251
MESH:D017202 Myocardial Ischemia resveratrol 8.1217015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.1212213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.5816411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 7.5819207477
MESH:D009205 Myocarditis resveratrol 4.4217322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.1317484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 15.8118551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 15.8118551238 7678174
MESH:D009336 Necrosis Trinitrotoluene 15.8118551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 12.523581430 9029167
MESH:D009362 Neoplasm Metastasis quinoline 12.52598648
MESH:D009362 Neoplasm Metastasis Tamoxifen 12.5219393235
MESH:D009362 Neoplasm Metastasis zoledronic acid 12.5219139120 17312309 15867366
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4019410462
MESH:D009369 Neoplasms Benzo(a)pyrene 7.2411141357
MESH:D009369 Neoplasms pirinixic acid 7.2417405874
MESH:D009369 Neoplasms Quercetin 7.2415185748
MESH:D009374 Neoplasms, Experimental resveratrol 3.678985016
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.6519189210 19200415 19196722
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 2.8914600291
MESH:D019636 Neurodegenerative Diseases Acetaminophen 12.4618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 12.4620387270
MESH:D019636 Neurodegenerative Diseases resveratrol 12.4617652729
MESH:D020078 Neurogenic Inflammation Quercetin 9.6517929310
MESH:D020078 Neurogenic Inflammation resveratrol 9.6517929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.7720387270
MESH:D009503 Neutropenia Mustard Gas 3.6616761898 7688884
MESH:D009765 Obesity pirinixic acid 1.7320558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 19.2216049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 19.2216049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 19.2214694615
MESH:D009784 Occupational Diseases Trinitrotoluene 19.2214694615 17852074 12819281
MESH:D010014 Osteolysis zoledronic acid 5.0315867366
MESH:D010018 Osteomalacia Phenobarbital 4.0217016548
MESH:D010024 Osteoporosis zoledronic acid 3.8317882678
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 9.1619495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 9.1617513867
MESH:D010051 Ovarian Neoplasms Quercetin 2.6319005980
MESH:D010146 Pain Acetaminophen 6.0716870215
MESH:D010146 Pain zoledronic acid 6.0716475674
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 11.3216540662
MESH:D010190 Pancreatic Neoplasms Mitomycin 11.3215113037
MESH:D010190 Pancreatic Neoplasms Phenobarbital 11.3216965848
MESH:D010190 Pancreatic Neoplasms Quercetin 11.3216965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3711578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9012520081
MESH:D010954 Plasmacytoma Selenium 4.5415087411
MESH:D011041 Poisoning Mustard Gas 3.4915727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2418163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 13.732563599
MESH:D011230 Precancerous Conditions Phenobarbital 13.732563599
MESH:D011230 Precancerous Conditions Quercetin 13.7319056647
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 8.4616679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.4611896295 11399792 11118676 11222880
MESH:D011371 Progeria marker/mechanism 15726408 17469202
MESH:D011471 Prostatic Neoplasms AGN 194204 2.0516000583
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.0517292933
MESH:D011471 Prostatic Neoplasms Quercetin 2.0514715546 17292933
MESH:D011471 Prostatic Neoplasms resveratrol 2.0517636462 16731767 17675339 17718901 15767336 17804756
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.0515067354
MESH:D011471 Prostatic Neoplasms Vitamin E 2.0515084515
MESH:D011471 Prostatic Neoplasms zoledronic acid 2.0519103299 12438248
MESH:D011537 Pruritus Ethinyl Estradiol 8.3915861022 16919318
MESH:D011537 Pruritus Mustard Gas 8.3918058305
MESH:D019310 Pseudolymphoma Phenobarbital 4.1512752131
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.8017720292 17894541 17620002 17266442 10334151
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.2416325855
MESH:D015427 Reperfusion Injury pirinixic acid 6.0019058328
MESH:D015427 Reperfusion Injury resveratrol 6.0015827377 16314181 17058453 17520802 16317513
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5118990726
OMIM:275210 RESTRICTIVE DERMOPATHY, LETHAL marker/mechanism
MESH:D012512 Sarcoma, Ewing's zoledronic acid 4.6116121404
MESH:D012554 Schistosomiasis japonica Quercetin 5.2016862918
MESH:D012594 Scleroderma, Localized marker/mechanism 15726408
MESH:D012640 Seizures 2,4-dinitrotoluene 12.2118551238
MESH:D012640 Seizures 2,6-dinitrotoluene 12.2118551238
MESH:D012640 Seizures Phenobarbital 12.213137016 4039156 16876388 11442880
MESH:D012640 Seizures Trinitrotoluene 12.2118551238
MESH:D003294 Seizures, Febrile Phenobarbital 4.486407741
MESH:D012848 Sinoatrial Block marker/mechanism 15996213
MESH:D012871 Skin Diseases Mustard Gas 4.7112880345 15451306 16961503
MESH:D012871 Skin Diseases Vitamin E 4.7118709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 8.4819755658 10029692
MESH:D012878 Skin Neoplasms resveratrol 8.488985016 15837718
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.4816192470
MESH:D013088 Spermatocele Ethinyl Estradiol 10.4116709447
MESH:D013088 Spermatocele Tamoxifen 10.4116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.7019457130
MESH:D013163 Splenomegaly Trinitrotoluene 4.8715817613
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.242093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.2418456281
MESH:D020521 Stroke Vitamin E 3.2516517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.1916321402
MESH:D017180 Tachycardia, Ventricular marker/mechanism 15996213
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3111994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8715669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5612697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.337505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 6.331399818
MESH:D014062 Tongue Neoplasms resveratrol 3.9216227395
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 14.3116049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 14.3116049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 14.3117053015
MESH:D001749 Urinary Bladder Neoplasms Quercetin 14.3116720314
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 14.3117572228 16712894 8653321
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 10.8510091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 10.8510091137
MESH:D014581 Urticaria Acetaminophen 2.6710982225
MESH:D002583 Uterine Cervical Neoplasms resveratrol 3.8117473185
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.4314692618
MESH:D014594 Uterine Neoplasms resveratrol 8.4317044934
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2512125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2414671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 3.9717488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9015886252
MESH:D014898 Werner Syndrome marker/mechanism
Pathway ID Pathway Name
REACT:578 Apoptosis
KEGG:05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
REACT:15380 Diabetes pathways
KEGG:05414 Dilated cardiomyopathy
KEGG:05410 Hypertrophic cardiomyopathy (HCM)
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA231
    • No data
    Releated disease ID Related disease Name
    PA444785Lipodystrophy
    PA152068054Acquired partial lipodystrophy
    PA445420Progeria
    PA445062Neoplasms
    PA443319Alzheimer Disease
    PA443632Cardiomyopathy, Dilated
    Releated drug ID Related drug Name
    PA152207466farnesyltransferase inhibitors
    PA452249antiarrhythmics, class i and iii
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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