AutismKB 2.0

Annotation Detail for CENPP


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Basic Information Top
Gene Symbol:CENPP ( CENP-P,FLJ33928 )
Gene Full Name: centromere protein P
Band: 9q22.31
Quick LinksEntrez ID:401541; OMIM: 611505; Uniprot ID:CENPP_HUMAN; ENSEMBL ID: ENSG00000188312; HGNC ID: 32933
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Cell Cycle, Mitotic
DNA Replication
Chromosome Maintenance
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of CENPP mRNAdecreases expression 20064835
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of CENPP mRNAaffects expression 17484886
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of CENPP mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of CENPP mRNAincreases expression 19482888
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 4.186195326
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0620127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.886695378
MESH:D018248 Adenoma, Liver Cell Phenobarbital 4.7117620307
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.7319183758
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9920146248 17474063
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.4316097048 15700767 3786805 15721981 10355542 15673190 16124888 16227642 18705752 16050911 16011737 16192424
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 3.2018788625
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 3.206705139 17173139 1701930 20007298 20935162
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1420419170
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.904080065
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 2.1321278145 15968718 7179309 2869522 15998439 17522070 7120509 16227642 6884620 4309450 3786805 9327722 3732212 10915739 15027814 16177239 10092053 6623471 19085960 11566570 19336974 7440962
MESH:D004421 Dystonia Phenobarbital 4.531851702
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.763659116
MESH:D004828 Epilepsies, Partial Phenobarbital 4.743922381 11558140
MESH:D004827 Epilepsy Phenobarbital 3.0820417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.966401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.907750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.763659116
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0916530937
MESH:D005234 Fatty Liver Carbon Tetrachloride 3.6561145 17595544 19224547 16239168 16045604 15959796 12795759 12631006
MESH:D005355 Fibrosis Carbon Tetrachloride 4.1018705752
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8520471113
MESH:D006505 Hepatitis Carbon Tetrachloride 4.1819110552 19900420
MESH:D006529 Hepatomegaly Phenobarbital 4.1316109766
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.2716899240
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.7415338365
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 7.3511408273 21278145 16239168 17174718 16943688 17334410 11903743 16221502 17157831
MESH:D008103 Liver Cirrhosis Phenobarbital 7.3521047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7518205269 16136751 18395914 16011737 12546737 17698563 12898905 12389079 18210741 16638106 12632514 14512876 15730626 16033810 17805973 16097048 15338365 16015684 17557913 12666154 18429990 14716496 18279442 17481882 16027843 18472332 16248980 17900296 10355542 18054572 12586293 12649538 15996030 14716833 17721639 18251166 18412020 15931870 12741479 15818738 15673190 17922224 15362042 14620537 18187930 17714472 18339082 18277467 12609069 17708605 15123356 18472094 18481824 18263696 18166357 18376398 17766677 12445418 13678700 17761835 18418968 14748882 17565644 15925388 17944888 18006644 18317297 17823541 18705752 15052691 15057751 15370692 16116963 15959796 12445421 17869086 12958196 17640975 17631135 16192424 12632512 14724832 15876570 18395095 15650968 17525996 15893842 18420326 11481614 17976157 18156304 20821823 12667390
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.3916246199 16964402 17285989 15720792 15830285
MESH:D008107 Liver Diseases Phenobarbital 4.3919363144
MESH:D017093 Liver Failure Carbon Tetrachloride 4.8215123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 4.1414706259 16899240
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 8.2421137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 8.2419294768
MESH:D008113 Liver Neoplasms Phenobarbital 8.248742319 21047994 19073162 19482888 15975961 19812893
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 6.8312014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 6.8317172636 6150874 1399818 2563599 18308698
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5720135361 17053015 6695378 20064080 18569708 20869020 20464547 18520028 18816296
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5316381670
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 5.2217484760
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3511141357
MESH:D010018 Osteomalacia Phenobarbital 5.1117016548
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.6116965848
MESH:D011230 Precancerous Conditions Phenobarbital 4.042563599
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9017292933
MESH:D019310 Pseudolymphoma Phenobarbital 5.3612752131
MESH:D012640 Seizures Phenobarbital 2.9711442880 4039156 3137016 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 5.566407741
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5419755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D013964 Thyroid Neoplasms Phenobarbital 3.391399818
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.3117053015
Pathway ID Pathway Name
REACT:152 Cell Cycle, Mitotic
REACT:22172 Chromosome Maintenance
REACT:383 DNA Replication
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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