AutismKB 2.0

Annotation Detail for LSP1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:LSP1 ( WP34,pp52 )
Gene Full Name: lymphocyte-specific protein 1
Band: 11p15.5
Quick LinksEntrez ID:4046; OMIM: 153432; Uniprot ID:LSP1_HUMAN; ENSEMBL ID: ENSG00000130592; HGNC ID: 6707
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
No data
Pathway IDPathway Name
200135p38 signaling mediated by MAPKAP kinases
No data
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
CANCER
breast cancer
Desease Name
Breast cancer
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in increased expression of LSP1 mRNAincreases expression 20406850
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of LSP1 mRNAincreases expression 18648102
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of LSP1 mRNAaffects expression 21346803
C105260 4-tert-octylphenol 4-tert-octylphenol results in increased expression of LSP1 mRNAincreases expression 17011747
D000082 Acetaminophen Acetaminophen affects the expression of LSP1 mRNAaffects expression 17562736
C006632 arsenic trioxide arsenic trioxide results in increased expression of LSP1 mRNAincreases expression 15761015
D004041 Dietary Fats Dietary Fats results in increased expression of LSP1 mRNAincreases expression 18042831
D004054 Diethylstilbestrol Diethylstilbestrol results in decreased expression of LSP1 mRNAdecreases expression 15289156
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of LSP1 mRNAincreases expression 17011747
D002117 Calcitriol Calcitriol results in increased expression of LSP1 mRNAincreases expression 12875902
D004958 Estradiol Estradiol results in decreased expression of LSP1 mRNAdecreases expression 15289156
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of LSP1 mRNAdecreases expression 17557909
D015025 Zearalenone Zearalenone results in decreased expression of LSP1 mRNAdecreases expression 17557909
D019833 Genistein Genistein results in decreased expression of LSP1 mRNAdecreases expression 15289156
C041786 palm oil palm oil results in increased expression of LSP1 mRNAincreases expression 18042831
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of LSP1 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in decreased expression of LSP1 mRNAdecreases expression 17426115
D012643 Selenium Selenium results in increased expression of LSP1 mRNAincreases expression 19244175
D014212 Tretinoin Tretinoin results in increased expression of LSP1 mRNAincreases expression 12875902
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 3.947525203
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9417505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.1018653653
MESH:D000230 Adenocarcinoma arsenic trioxide 10.1411798837 19825857
MESH:D000230 Adenocarcinoma Estradiol 10.1411473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.1414692618
MESH:D000230 Adenocarcinoma Genistein 10.1411473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.743712494
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.4716434500
MESH:D000505 Alopecia Tretinoin 3.6015955085
MESH:D000686 Amyloidosis Diethylstilbestrol 4.4615469931
MESH:D000799 Angioedema Acetaminophen 3.8410982225
MESH:D001161 Arteriosclerosis Dietary Fats 9.8615238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.8611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.1615885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.1616412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2616292516
MESH:D001249 Asthma Tretinoin 2.3416456186
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001471 Barrett Esophagus Tretinoin 4.3916935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.0211289319 1440618
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 15.2516206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.2519483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 15.2516197459 16206674
MESH:D001943 Breast Neoplasms marker/mechanism 17529967 20453838
MESH:D001943 Breast Neoplasms Calcitriol 2.9611237771
MESH:D001943 Breast Neoplasms Dietary Fats 2.9620435547
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.9617129689 15324884
MESH:D001943 Breast Neoplasms Estradiol 2.9617289903 16675129 17018787 17261762 18497071 19861407 12948864 14630087
MESH:D001943 Breast Neoplasms Genistein 2.9616873071 17200150 16541309
MESH:D001943 Breast Neoplasms Tretinoin 2.9616443354 16873071 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.5816813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.3111589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4516111702
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.1616168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 16.9116705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 16.917296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 16.913084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 16.9111135700 16217749 15073043 14691202 15553829
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 16.9115948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Estradiol 16.9116924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 16.9116924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 16.911917145
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.8719014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.667296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.1012490120
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 4.7611237771
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.7616096774 16051514
MESH:D002318 Cardiovascular Diseases Genistein 3.2916332659
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 12.3014694615
MESH:D002386 Cataract Acetaminophen 12.3010977129
MESH:D002386 Cataract Tretinoin 12.3017460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 11.096135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 11.097505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 11.0918566989
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.5816129372
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.289022650 19486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.2817110522 16919318 16105132 17681005 15861022 11677210 17333356
MESH:D002779 Cholestasis pirinixic acid 13.2819176532
MESH:D002822 Choriocarcinoma Tretinoin 5.1616461808
MESH:D002972 Cleft Palate Tretinoin 2.669407595
MESH:D003092 Colitis Selenium 9.4517936198
MESH:D003092 Colitis Tretinoin 9.4517035595
MESH:D003093 Colitis, Ulcerative marker/mechanism 21297633
MESH:D003110 Colonic Neoplasms Genistein 2.2817182828
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 4.1415095906
MESH:D023903 Coronary Restenosis arsenic trioxide 4.1712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.6710525206
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.679224671 16925845 9211117 10589399 9142499 17551590 9664655 9125849 14991402 8800419
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.5412952375 16002989
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.0018551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.0815213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.798156756 8970840 18759878 2524372 12868966 11906362 14531868 11298694
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4118249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.473621924 2952479
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 2.4816647724
MESH:D003928 Diabetic Nephropathies Estradiol 3.3919279558
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 11.9618551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 11.967440962 8291058 18692083 6482804 6679447 1440618 18289764 11289319 9653073 16192314 9022650 9328219 18648102
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 11.9621346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.9616485898 11739529 17906064 11529661 12705907 10774834 12958197 10663392 10915739 14550746 16177239 12540782 16109766 2444490 17562736 19923254 11421492 18713872 17522070 11743745 16781746 12392966 19085960 19420014 14725611 12594235 15968718 15619225 18071297 19164858 19370779 12153990 16227642 16393943 16081117 19739265 11834606 11461765 14986274 19416960 11287661
MESH:D056486 Drug-Induced Liver Injury Selenium 11.9615131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1019426721
MESH:D050171 Dyslipidemias Dietary Fats 3.4418367378
MESH:D004487 Edema pirinixic acid 2.4612083418
MESH:D004489 Edema, Cardiac Tretinoin 4.4718230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 9.0415138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.0412538720
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 11.8716402032
MESH:D004714 Endometrial Hyperplasia Genistein 11.8716402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 17.6915700306 16804899
MESH:D016889 Endometrial Neoplasms Estradiol 17.6918566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Genistein 17.6911473722
MESH:D016889 Endometrial Neoplasms Tretinoin 17.6916569247
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.453581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.4512903497
MESH:D005124 Eye Abnormalities Tretinoin 3.569664655 16938888
MESH:D005234 Fatty Liver arsenic trioxide 18.6115073043
MESH:D005234 Fatty Liver Dietary Fats 18.6119004024 17967931 19551842 18296743
MESH:D005234 Fatty Liver Ethinyl Estradiol 18.6115345470
MESH:D005234 Fatty Liver pirinixic acid 18.6120131406 19236843
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.6416002989 16611131 16534752 16513791 15751030
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.026705139
MESH:D005355 Fibrosis Dietary Fats 8.7918296743
MESH:D005355 Fibrosis Tretinoin 8.7917994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.2416904648
MESH:D005756 Gastritis Acetaminophen 3.6816983495
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.9416452187
MESH:D005909 Glioblastoma Genistein 7.1616598420
MESH:D005909 Glioblastoma Tretinoin 7.1617312396
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.027505956
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.1716096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.1616084493
MESH:D006330 Heart Defects, Congenital Tretinoin 2.8814991402 9664655
MESH:D006333 Heart Failure pirinixic acid 6.9120558911
MESH:D006333 Heart Failure Selenium 6.9117162251
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.506705139
MESH:D006529 Hepatomegaly pirinixic acid 2.9816221962 18467677 19176532 19772884
MESH:D006558 Herpes Genitalis Estradiol 5.0315709030
MESH:D019584 Hot Flashes Estradiol 3.7517088409
MESH:D006930 Hyperalgesia Acetaminophen 7.5716870215
MESH:D006930 Hyperalgesia Tretinoin 7.5716870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.5721332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.5516778211
MESH:D006943 Hyperglycemia pirinixic acid 3.1620558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.6021332399
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 10.7915034207
MESH:D006965 Hyperplasia Diethylstilbestrol 10.7912960047 14722030
MESH:D007021 Hypospadias Diethylstilbestrol 11.2016002989
MESH:D007021 Hypospadias Ethinyl Estradiol 11.2016569931 16945680
MESH:D007246 Infertility Diethylstilbestrol 4.3415036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4717937319
MESH:D007249 Inflammation Dietary Fats 2.4220412841
MESH:D007251 Influenza, Human Selenium 4.2016624496
MESH:D007333 Insulin Resistance Dietary Fats 12.2118457598 11836018
MESH:D007333 Insulin Resistance Estradiol 12.2116393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 12.2116306350
MESH:D007410 Intestinal Diseases Tretinoin 3.7517994277
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.029022650 8074119
MESH:D007569 Jaw Abnormalities Tretinoin 3.8817551590 15992940
MESH:D007674 Kidney Diseases Acetaminophen 5.8412587719 15629191
MESH:D007674 Kidney Diseases Estradiol 5.8415618244
MESH:D007676 Kidney Failure, Chronic Selenium 3.8716518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 17.6316705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 17.636582329
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 17.6314681315 15003126 16762066
MESH:D007680 Kidney Neoplasms Estradiol 17.6315610895
MESH:D007859 Learning Disorders Diethylstilbestrol 4.0517184923
MESH:D007938 Leukemia arsenic trioxide 10.4415070760
MESH:D007938 Leukemia Genistein 10.4418980019 17468513
MESH:D007938 Leukemia Tretinoin 10.4417143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.7817077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.3016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.4114633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.4119077051
MESH:D007951 Leukemia, Myeloid Tretinoin 9.4119285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.8719850784 16467208 20471514 17050201 16968895
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.8719850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.5917869043 12712474 16331271 17712046 16966277 17107899 17217047 15336539 15748426 9834237 16330433 19075265 12018890 11468182 11161223 16823087 15622746 16112521 19225113 19642359 12679006 19035177 15213294 17649720 16891316
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.599834237 19075265 17712046 17361223 19642359 16935935 17339181 16140955 16788101 17506722 17107899 12679006 16891316 15748426 16823087 17217047 17294898 16331271 17649720 17368321 19035177 17301526 19029980 19225113 16766008
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.3416882451
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.299224671
MESH:D008103 Liver Cirrhosis Dietary Fats 2.8618296743
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.1815034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.9414659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 4.9417823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.9415474484
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.9418397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 1.6219784758 12587719 12969438 11587558 19460945 16610002 19014921 16611625
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2217185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 10.657678174
MESH:D008113 Liver Neoplasms arsenic trioxide 10.6514682389
MESH:D008113 Liver Neoplasms Diethylstilbestrol 10.6515890375 16712894
MESH:D008113 Liver Neoplasms pirinixic acid 10.6516377806 20007298 15890375
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 9.786135515 2876784 2876786
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 9.78598648 3712494 6587162 1399818
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 9.7820377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3315213294
MESH:D008175 Lung Neoplasms arsenic trioxide 1.8611798837 19825857
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.1415166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.4615700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.5216002989
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 9.9217203775 11807958 16891317 11408345
MESH:D008325 Mammary Neoplasms, Experimental Genistein 9.9212929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Selenium 9.9215318939
MESH:D020149 Manganese Poisoning Estradiol 4.4819453300
MESH:D008527 Medulloblastoma Tretinoin 2.7817453147
MESH:D008545 Melanoma Tretinoin 1.9416752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5519513568
MESH:D008591 Meningomyelocele Tretinoin 4.4116940565
MESH:D008654 Mesothelioma Selenium 2.7815107826
MESH:D009101 Multiple Myeloma arsenic trioxide 3.0919417148 11468182 15949261 19549372 14977855
MESH:D009135 Muscular Diseases pirinixic acid 3.4916239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.6718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.3516882451 16105982
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.3517596541
MESH:D009203 Myocardial Infarction Genistein 5.6517141266
MESH:D009203 Myocardial Infarction pirinixic acid 5.6519151258
MESH:D015428 Myocardial Reperfusion Injury Estradiol 14.0816810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 14.0817141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 14.0816411023
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.8518551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.9416624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.463581430
MESH:D009369 Neoplasms Diethylstilbestrol 8.2115313581
MESH:D009369 Neoplasms pirinixic acid 8.2117405874
MESH:D009369 Neoplasms Tretinoin 8.2116946489 16594593
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7217289903
MESH:D009421 Nervous System Malformations Diethylstilbestrol 23.3711399458
MESH:D009421 Nervous System Malformations Estradiol 23.3716427766 11399458
MESH:D009421 Nervous System Malformations Genistein 23.3716427766
MESH:D009421 Nervous System Malformations Tretinoin 23.379125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 12.056679447
MESH:D009436 Neural Tube Defects arsenic trioxide 12.0510525206
MESH:D009436 Neural Tube Defects Tretinoin 12.059142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8518514411
MESH:D009765 Obesity Dietary Fats 4.4220518802 21332399 18674790 17217161 20132043 16723640 11836018 18457598 19632207
MESH:D009765 Obesity pirinixic acid 4.4220558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 15.0516049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 15.056482804 4026338
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 15.0514694615
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.023988306
MESH:D010024 Osteoporosis Genistein 3.2419401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 4.0716169203
MESH:D010051 Ovarian Neoplasms arsenic trioxide 11.2519769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Estradiol 11.2519401270
MESH:D010051 Ovarian Neoplasms Genistein 11.2519005980
MESH:D010051 Ovarian Neoplasms Tretinoin 11.2516936753
MESH:D010146 Pain Acetaminophen 6.5316870215
MESH:D010146 Pain Tretinoin 6.5316870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 5.2615580305
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.2615976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6711578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.477296757
MESH:D010235 Paraganglioma arsenic trioxide 4.1419927285
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.476228378
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.1714722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.6615687265 16977796
MESH:D010954 Plasmacytoma Selenium 4.8915087411
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 4.1017184923
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.7715572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8720887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8719131511
MESH:D011471 Prostatic Neoplasms Calcitriol 1.8718247401 16289102 15754350 16644109 12479363
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 1.8715046698 17136230 15846301
MESH:D011471 Prostatic Neoplasms Estradiol 1.8716740699
MESH:D011471 Prostatic Neoplasms Genistein 1.8715256057 15378649 16925846
MESH:D011507 Proteinuria Tretinoin 3.5916636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.3015861022 16919318
MESH:D011625 Pterygium Tretinoin 4.7816723453
MESH:D015427 Reperfusion Injury pirinixic acid 2.3819058328
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.363692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.0816283617 16116481
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.9416646077
MESH:D012640 Seizures 2,6-dinitrotoluene 2.5218551238
MESH:D012878 Skin Neoplasms Tretinoin 2.6016467112
MESH:D013088 Spermatocele Diethylstilbestrol 11.7216709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 11.7216709447
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.4517007042
MESH:D013274 Stomach Neoplasms Tretinoin 2.4517261132
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1315669648
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 11.876582329 7505956 1399818 6587162 3712494
MESH:D013964 Thyroid Neoplasms arsenic trioxide 11.8719014326
MESH:D013964 Thyroid Neoplasms Tretinoin 11.8716026305 17045167
MESH:D013978 Tibial Fractures Estradiol 4.6919048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.7716051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.9515213294
MESH:D014376 Tuberculosis Tretinoin 3.2116040207
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 11.8816049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 11.888074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 11.8820435036 12973940 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 11.8816452187 16712894 17306315
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.3110091137
MESH:D014581 Urticaria Acetaminophen 2.9610982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 9.4516175088
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 9.4516129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.1714652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 9.4215809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.4214692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.6116752155
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.4216002989 16513791
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5214671159 15869587
MESH:D014820 Vitiligo Tretinoin 4.0416761959
MESH:D015430 Weight Gain Dietary Fats 3.7216723640
MESH:D009396 Wilms Tumor Tretinoin 3.9516287080
Pathway ID Pathway Name
KEGG:05152 Tuberculosis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA30472
  • No data
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    PA443560Breast Neoplasms
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018