AutismKB 2.0

Annotation Detail for TACSTD2


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Basic Information Top
Gene Symbol:TACSTD2 ( EGP-1,EGP1,GA733-1,GA7331,GP50,M1S1,TROP2 )
Gene Full Name: tumor-associated calcium signal transducer 2
Band: 1p32.1
Quick LinksEntrez ID:4070; OMIM: 137290; Uniprot ID:TACD2_HUMAN; ENSEMBL ID: ENSG00000184292; HGNC ID: 11530
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1919Corneal disease
1934Cancer
No data
No data
Desease Name
Corneal dystrophy, gelatinous drop-like
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C103303 alitretinoin alitretinoin results in increased expression of TACSTD2 mRNAincreases expression 15982314
C068073 Am 580 Am 580 results in decreased expression of TACSTD2 mRNAdecreases expression 16982809
C006632 arsenic trioxide arsenic trioxide results in decreased expression of TACSTD2 mRNAdecreases expression 19128835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TACSTD2 mRNAdecreases expression 20018196
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of TACSTD2 mRNAincreases expression 15289156
D002117 Calcitriol Calcitriol results in increased expression of TACSTD2 mRNAincreases expression 16002434
D004958 Estradiol Estradiol affects the expression of TACSTD2 mRNAaffects expression 15598610
D004958 Estradiol Estradiol results in increased expression of TACSTD2 mRNAincreases expression 15289156
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of TACSTD2 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of TACSTD2 mRNAincreases expression 17557909
15576828
D019833 Genistein Genistein results in increased expression of TACSTD2 mRNAincreases expression 15289156
C008493 methylselenic acid methylselenic acid results in decreased expression of TACSTD2 mRNAdecreases expression 18548127
D011374 Progesterone Progesterone affects the expression of TACSTD2 mRNAaffects expression 17251523
D015474 Isotretinoin Isotretinoin results in increased expression of TACSTD2 mRNAincreases expression 15982314
C089730 rosiglitazone rosiglitazone results in decreased expression of TACSTD2 mRNAdecreases expression 16982809
C017947 sodium arsenite sodium arsenite results in increased expression of TACSTD2 mRNAincreases expression 12377979
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of TACSTD2 mRNAincreases expression 12377990
D014212 Tretinoin Tretinoin metabolite results in increased expression of TACSTD2 mRNAincreases expression 15982314
D014212 Tretinoin Tretinoin results in increased expression of TACSTD2 mRNAincreases expression 15982314
C025643 vinclozolin vinclozolin affects the expression of TACSTD2 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Isotretinoin 8.6718769834
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.6715322242 11752688 14514962
MESH:D000015 Abnormalities, Multiple Isotretinoin 4.9618769834
MESH:D017486 Acneiform Eruptions Isotretinoin 6.2816232082
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 12.0017505938
MESH:D000152 Acne Vulgaris Isotretinoin 12.0018769834 16185265
MESH:D000230 Adenocarcinoma arsenic trioxide 10.1419825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 10.1411473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.1414692618
MESH:D000230 Adenocarcinoma Genistein 10.1411473722
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.3716835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.7015276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.9017306315 16712894
MESH:D000505 Alopecia Tretinoin 3.6015955085
MESH:D000544 Alzheimer Disease rosiglitazone 2.8519621015
MESH:D000686 Amyloidosis Diethylstilbestrol 4.4615469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9311748828
MESH:D001008 Anxiety Disorders vinclozolin 3.6219015723
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.1615885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.1616412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2616292516
MESH:D001249 Asthma Tretinoin 2.3416456186
MESH:D001471 Barrett Esophagus Tretinoin 4.3916935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 15.2416206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.2412125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 15.2416206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7515746008
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.3417868700
MESH:D001930 Brain Injuries Progesterone 4.2415380490 15665606 15845082
MESH:D001943 Breast Neoplasms alitretinoin 4.7316344269
MESH:D001943 Breast Neoplasms Calcitriol 4.7311237771
MESH:D001943 Breast Neoplasms Diethylstilbestrol 4.7315324884 17129689
MESH:D001943 Breast Neoplasms Estradiol 4.7319861407 17289903 16675129 12948864 14630087 17018787 18497071 17261762
MESH:D001943 Breast Neoplasms Genistein 4.7316873071 16541309 17200150
MESH:D001943 Breast Neoplasms Progesterone 4.7316175315 15562024 17614352
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 4.7320435547
MESH:D001943 Breast Neoplasms Tretinoin 4.7316443354 16873071 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.5816813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.3111589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4516111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7816835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.1616168501
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.3615553829 14691202 11135700 15073043 16217749
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 11.3616924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.3616924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 11.3616924424
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 11.3615276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.361917145
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.8719014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.1012490120
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 10.8211237771
MESH:D002294 Carcinoma, Squamous Cell Isotretinoin 10.8211237771
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 10.8218572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 10.8216051514 16096774
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3518670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Genistein 3.2916332659
MESH:D002386 Cataract Am 580 7.8317460283
MESH:D002386 Cataract Tretinoin 7.8317460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.1120889678
MESH:D002471 Cell Transformation, Neoplastic Estradiol 11.1118566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 11.1120056578 19524636
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.5816129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1416835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.8615861022 17681005 17110522 16105132 17333356 16919318 11677210
MESH:D002822 Choriocarcinoma Tretinoin 5.1616461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.7412621046 15340226 15668235 8697196 16354765
MESH:D002972 Cleft Palate Tretinoin 5.749407595
MESH:D003092 Colitis Am 580 9.8917035595
MESH:D003092 Colitis Tretinoin 9.8917035595
MESH:D003110 Colonic Neoplasms Genistein 2.2817182828
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0417141729 14669216
MESH:C535480 Corneal dystrophy, gelatinous drop-like marker/mechanism
MESH:D023903 Coronary Restenosis arsenic trioxide 4.1712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 5.4310525206
MESH:D019465 Craniofacial Abnormalities Isotretinoin 5.4318769834 9879862
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 5.4310048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 5.4316925845 8800419 10589399 9224671 14991402 9125849 17551590 9142499 9664655 9211117
MESH:D003456 Cryptorchidism Diethylstilbestrol 11.3212952375 16002989
MESH:D003456 Cryptorchidism vinclozolin 11.3214966744
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.0815213294
MESH:D003920 Diabetes Mellitus rosiglitazone 4.2817446233
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 7.1816647724
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 7.1812642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 7.1817107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.3919279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.4817187935
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 1.5320420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7411462148
MESH:D004487 Edema rosiglitazone 6.9112083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.9112711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.9515322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 11.9518230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 15.2915138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.2912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 15.2917692515
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 11.8716402032
MESH:D004714 Endometrial Hyperplasia Genistein 11.8716402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 17.6916804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 17.6919148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Genistein 17.6911473722
MESH:D016889 Endometrial Neoplasms Tretinoin 17.6916569247
MESH:D004715 Endometriosis Progesterone 8.8716134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.8710568697 9294722
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.4420426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.4412903497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.7811564622
MESH:D005124 Eye Abnormalities Tretinoin 8.789664655 16938888
MESH:D005234 Fatty Liver arsenic trioxide 13.1115073043
MESH:D005234 Fatty Liver Ethinyl Estradiol 13.1115345470
MESH:D005234 Fatty Liver rosiglitazone 13.1119196556
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.6416513791 15751030 16611131 16002989 16534752
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4411858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.5720067830
MESH:D005355 Fibrosis Tretinoin 8.5717994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.2416904648
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.9316973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.3016417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 12.7916452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 12.7916452187
MESH:D005909 Glioblastoma Genistein 7.1616598420
MESH:D005909 Glioblastoma Tretinoin 7.1617312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5910696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.1716096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.1616084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.5010048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 6.509664655 14991402
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3211000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.8816120746 12621046 15340226
MESH:D006558 Herpes Genitalis Estradiol 5.0315709030
MESH:D006689 Hodgkin Disease sodium arsenite 3.1312676792
MESH:D019584 Hot Flashes Estradiol 3.7517088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0518606429 15340226 16354765 8697196 16959395
MESH:D006930 Hyperalgesia rosiglitazone 8.0112083418
MESH:D006930 Hyperalgesia Tretinoin 8.0116870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.5516778211
MESH:D006965 Hyperplasia Diethylstilbestrol 4.4212960047 14722030
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9018850075 18670907
MESH:D007021 Hypospadias Diethylstilbestrol 11.2016002989
MESH:D007021 Hypospadias Ethinyl Estradiol 11.2016569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.3915869954
MESH:D007246 Infertility Diethylstilbestrol 4.3415036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 11.1317937319
MESH:D007248 Infertility, Male sodium arsenite 11.1312646999 15346721
MESH:D007248 Infertility, Male vinclozolin 11.1316467254
MESH:D007249 Inflammation Progesterone 8.3415869954
MESH:D007249 Inflammation rosiglitazone 8.3412083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.3412878042 12200463
MESH:D007333 Insulin Resistance Estradiol 7.5816627594 16393666
MESH:D007333 Insulin Resistance rosiglitazone 7.5816306350
MESH:D007410 Intestinal Diseases Tretinoin 3.7517994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.8716580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.8715992940 17551590
MESH:D017492 Keratosis, Seborrheic alitretinoin 5.6316144296
MESH:D007674 Kidney Diseases Estradiol 6.0615618244
MESH:D007674 Kidney Diseases sodium arsenite 6.0620008137
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 7.4816762066 14681315 15003126
MESH:D007680 Kidney Neoplasms Estradiol 7.4815610895
MESH:D007859 Learning Disorders Diethylstilbestrol 4.0517184923
MESH:D007938 Leukemia arsenic trioxide 10.4415070760
MESH:D007938 Leukemia Genistein 10.4417468513 18980019
MESH:D007938 Leukemia Tretinoin 10.4417143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.7812560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.3016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.4114633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.4119077051
MESH:D007951 Leukemia, Myeloid Tretinoin 9.4116482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.8719850784 16467208 20471514 17050201 16968895
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.8719850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.5912018890 15622746 16330433 11161223 16112521 16823087 9834237 12679006 19035177 19642359 11468182 17869043 17217047 12712474 16331271 16966277 15336539 17649720 15748426 19225113 17712046 16891316 15213294 17107899 19075265
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.5916766008 19035177 17217047 19642359 16331271 17294898 16140955 19029980 17368321 17361223 9834237 17301526 15748426 17107899 17712046 16891316 17506722 17339181 12679006 16935935 19225113 16788101 19075265 17649720 16823087
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.3416882451
MESH:D007984 Leydig Cell Tumor vinclozolin 4.7216417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.299224671
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.7214716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 6.7217823541
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 6.7215980055 17347453
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.7212878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.7218397230 16248980
MESH:D008113 Liver Neoplasms arsenic trioxide 10.6614682389
MESH:D008113 Liver Neoplasms Diethylstilbestrol 10.6616712894 15890375
MESH:D008113 Liver Neoplasms sodium arsenite 10.6615276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.6616984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 5.7620377131
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 5.7612151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3315213294
MESH:D008171 Lung Diseases sodium arsenite 3.1619095001
MESH:D008175 Lung Neoplasms alitretinoin 6.6016413115
MESH:D008175 Lung Neoplasms arsenic trioxide 6.6019825857 11798837
MESH:D008175 Lung Neoplasms Isotretinoin 6.6015899809
MESH:D008175 Lung Neoplasms sodium arsenite 6.6017077188 16712894 17306315 19931552 15276417
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.6011884234 19555203
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.1415166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.4615700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.5216002989
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 14.2116891317 11807958 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Genistein 14.2114578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 14.2111408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 14.2116827153
MESH:D020149 Manganese Poisoning Estradiol 4.4819453300
MESH:D008527 Medulloblastoma Tretinoin 2.7817453147
MESH:D008545 Melanoma Isotretinoin 5.2417237267
MESH:D008545 Melanoma sodium arsenite 5.2419082730 16487513
MESH:D008545 Melanoma Tretinoin 5.2416752155
MESH:D008591 Meningomyelocele Tretinoin 4.4116940565
MESH:D024821 Metabolic Syndrome X rosiglitazone 4.3617261469
MESH:D009101 Multiple Myeloma arsenic trioxide 3.0911468182 15949261 14977855 19417148 19549372
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.6718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.3516105982 16882451
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.3517596541
MESH:D009203 Myocardial Infarction Genistein 2.8517141266
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0012213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.4616810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 8.4617141266
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.9416624393
MESH:D009369 Neoplasms alitretinoin 11.8616946489
MESH:D009369 Neoplasms Diethylstilbestrol 11.8615313581
MESH:D009369 Neoplasms sodium arsenite 11.8611559025
MESH:D009369 Neoplasms Tretinoin 11.8616946489 16594593
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.6520056578
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7217289903
MESH:D009421 Nervous System Malformations Diethylstilbestrol 30.6011399458
MESH:D009421 Nervous System Malformations Estradiol 30.6016427766 11399458
MESH:D009421 Nervous System Malformations Genistein 30.6016427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 30.6014600291
MESH:D009421 Nervous System Malformations Tretinoin 30.609125849
MESH:D009436 Neural Tube Defects arsenic trioxide 12.0810525206
MESH:D009436 Neural Tube Defects sodium arsenite 12.0812854658
MESH:D009436 Neural Tube Defects Tretinoin 12.089142499
MESH:D009447 Neuroblastoma Isotretinoin 4.0317368321
MESH:D010024 Osteoporosis Genistein 3.2419401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 4.0716169203
MESH:D010051 Ovarian Neoplasms arsenic trioxide 18.8012452020 16624393 19769630
MESH:D010051 Ovarian Neoplasms Estradiol 18.8019401270
MESH:D010051 Ovarian Neoplasms Genistein 18.8019005980
MESH:D010051 Ovarian Neoplasms Progesterone 18.8017393432 16525653
MESH:D010051 Ovarian Neoplasms sodium arsenite 18.8017306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 18.8016936753
MESH:D010146 Pain Tretinoin 2.8816870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 5.2615580305
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.2615976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6711578682
MESH:D010235 Paraganglioma arsenic trioxide 4.1419927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2512520081
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.1714722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.6615687265 16977796
MESH:D017499 Porokeratosis alitretinoin 6.0016144296
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5418163543
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 23.2617184923
MESH:D011297 Prenatal Exposure Delayed Effects Isotretinoin 23.2618769834
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 23.2611118676 11399792 11222880 11896295
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 23.2618042343 19015723 18220299
MESH:D011469 Prostatic Diseases vinclozolin 4.9318220299
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.7715572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8720887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.1019131511
MESH:D011471 Prostatic Neoplasms Calcitriol 2.1016644109 15754350 18247401 12479363 16289102
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.1017136230 15846301 15046698
MESH:D011471 Prostatic Neoplasms Estradiol 2.1016740699
MESH:D011471 Prostatic Neoplasms Genistein 2.1015256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms methylselenic acid 2.1016205645
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.1016039940
MESH:D011472 Prostatitis vinclozolin 4.9318629315
MESH:D011507 Proteinuria Tretinoin 3.5916636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.3015861022 16919318
MESH:D011596 Psychomotor Disorders Isotretinoin 5.9118769834
MESH:D011625 Pterygium Tretinoin 4.7816723453
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8218990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.0816283617 16116481
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.8518045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.9416646077
MESH:D012878 Skin Neoplasms sodium arsenite 9.3718572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.3716192470
MESH:D012878 Skin Neoplasms Tretinoin 9.3716467112
MESH:D013088 Spermatocele Diethylstilbestrol 11.7216002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 11.7216709447
MESH:D013119 Spinal Cord Injuries Progesterone 4.2716503802 15862959
MESH:D016135 Spinal Dysraphism sodium arsenite 3.7812854658
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.4517007042
MESH:D013274 Stomach Neoplasms Tretinoin 2.4517261132
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1315669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9012697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 7.1519014326
MESH:D013964 Thyroid Neoplasms Tretinoin 7.1516026305 17045167
MESH:D013978 Tibial Fractures Estradiol 4.6919048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.7716051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.9515213294
MESH:D014376 Tuberculosis Tretinoin 3.2116040207
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.3512973940 12845720 20435036 11780464
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 8.3516712894 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.3516452187 16712894 11723127 17306315
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 15.7816175088
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 15.7811813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 15.7816129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.1714652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 9.4216690809 15809267
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.4214692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.6116752155
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.4216513791 16002989
MESH:D014652 Vascular Diseases sodium arsenite 4.4217056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5912125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5214671159 15869587
MESH:D014820 Vitiligo Tretinoin 4.0416761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2515886252
MESH:D009396 Wilms Tumor Tretinoin 3.9516287080
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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