AutismKB 2.0

Annotation Detail for MAD2L1


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Basic Information Top
Gene Symbol:MAD2L1 ( HSMAD2,MAD2 )
Gene Full Name: MAD2 mitotic arrest deficient-like 1 (yeast)
Band: 4q27
Quick LinksEntrez ID:4085; OMIM: 601467; Uniprot ID:MD2L1_HUMAN; ENSEMBL ID: ENSG00000164109; HGNC ID: 6763
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04914Progesterone-mediated oocyte maturation
hsa04110Cell cycle
hsa04114Oocyte meiosis
Pathway IDPathway Name
APC-Cdc20 mediated degradation of Nek2A
Cell Cycle, Mitotic
DNA Replication
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Cell Cycle Checkpoints
No data
No data
Pathway IDPathway Name
500396APC/C:Cdc20 mediated degradation of mitotic proteins
500328Inactivation of APC/C via direct inhibition of the APC/C complex
500325Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
500327Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindl
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1934Cancer
2164Barrett's esophagus
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C404910 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of MAD2L1 mRNAincreases expression 20826375
C404910 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the expression of MAD2L1 mRNAaffects expression 19414516
C063002 2,3-dimethoxy-1,4-naphthoquinone 2,3-dimethoxy-1,4-naphthoquinone results in increased expression of MAD2L1 mRNAincreases expression 19031421
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of MAD2L1 mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of MAD2L1 mRNAincreases expression 18648102
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of MAD2L1 proteinaffects expression 20106945
C015001 arsenite arsenite results in decreased expression of MAD2L1 mRNAdecreases expression 18929588
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of MAD2L1 mRNAdecreases expression 20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MAD2L1 mRNAdecreases expression 20382639
C053541 bicalutamide bicalutamide results in decreased expression of MAD2L1 mRNAdecreases expression 15638997
C006780 bisphenol A bisphenol A results in increased expression of MAD2L1 mRNAincreases expression 20826375
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of MAD2L1 mRNAaffects expression 17484886
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in decreased expression of MAD2L1 mRNAdecreases expression 16934159
D016572 Cyclosporine Cyclosporine results in decreased expression of MAD2L1 mRNAdecreases expression 20106945
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of MAD2L1 mRNAincreases expression 17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MAD2L1 mRNA]decreases reaction|increases expression 17854601
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of MAD2L1 mRNAincreases expression 16636312
C067311 docetaxel MAD2L1 protein affects the susceptibility to docetaxelaffects response to substance 18691855
D004317 Doxorubicin Doxorubicin results in decreased expression of MAD2L1 proteindecreases expression 15870702
D004317 Doxorubicin MAD2L1 protein affects the susceptibility to Doxorubicinaffects response to substance 16217747
D004958 Estradiol Estradiol results in increased expression of MAD2L1 mRNAincreases expression 20826375
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of MAD2L1 mRNAincreases expression 14976129
D005472 Fluorouracil Fluorouracil affects the expression of MAD2L1 mRNAaffects expression 16557594
D005472 Fluorouracil Fluorouracil results in decreased expression of MAD2L1 mRNAdecreases expression 17039268
D006918 Hydroxyurea Hydroxyurea results in decreased expression of MAD2L1 mRNAdecreases expression 12929121
C051890 irinotecan irinotecan metabolite results in decreased expression of MAD2L1 mRNAdecreases expression 15956246
C051890 irinotecan irinotecan results in decreased expression of MAD2L1 mRNAdecreases expression 15956246
D037742 Nanotubes, Carbon Nanotubes, Carbon results in decreased expression of MAD2L1 mRNAdecreases expression 15585362
D010126 Ozone TTPA protein affects the reaction [Ozone results in increased expression of MAD2L1 mRNA]affects reaction|increases expression 19555225
D017239 Paclitaxel MAD2L1 protein affects the susceptibility to Paclitaxelaffects response to substance 18691855
D017239 Paclitaxel Paclitaxel results in decreased expression of MAD2L1 mRNAdecreases expression 12929121
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of MAD2L1 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital affects the expression of MAD2L1 mRNAaffects expression 19136022
D010634 Phenobarbital Phenobarbital results in increased expression of MAD2L1 mRNAincreases expression 19482888
C006253 pirinixic acid pirinixic acid affects the expression of MAD2L1 mRNAaffects expression 19136022
C006253 pirinixic acid pirinixic acid results in increased expression of MAD2L1 mRNAincreases expression 18301758
17950772
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of MAD2L1 mRNA]increases expression|increases reaction 17950772
D011374 Progesterone Progesterone results in decreased expression of MAD2L1 mRNAdecreases expression 16966611
D011794 Quercetin Quercetin results in decreased expression of MAD2L1 mRNAdecreases expression 15309432
C059514 resveratrol resveratrol results in decreased expression of MAD2L1 mRNAdecreases expression 15767336
C059514 resveratrol resveratrol results in increased expression of MAD2L1 mRNAincreases expression 16081268
C115461 SC 560 SC 560 results in decreased expression of MAD2L1 mRNAdecreases expression 14633654
C115461 SC 560 SC 560 results in decreased expression of MAD2L1 proteindecreases expression 14633654
C017947 sodium arsenite sodium arsenite results in decreased expression of MAD2L1 mRNAdecreases expression 12377979
C017947 sodium arsenite sodium arsenite results in decreased expression of MAD2L1 mRNAdecreases expression 16014739
17998272
C025462 sulindac sulfide sulindac sulfide results in decreased expression of MAD2L1 mRNAdecreases expression 12734198
C025462 sulindac sulfide sulindac sulfide results in decreased expression of MAD2L1 proteindecreases expression 12734198
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased expression of MAD2L1 mRNAincreases expression 19031421
D014747 Vinblastine MAD2L1 protein affects the susceptibility to Vinblastineaffects response to substance 16217747
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 3.096195326
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5817505938
MESH:D058186 Acute Kidney Injury resveratrol 3.5416538975
MESH:D055371 Acute Lung Injury pirinixic acid 2.7918653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 12.4820127859 20464547
MESH:D000230 Adenocarcinoma Doxorubicin 12.4817418594
MESH:D000230 Adenocarcinoma Estradiol 12.4811473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 12.4814692618
MESH:D000230 Adenocarcinoma Fluorouracil 12.4817638652
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 14.263712494
MESH:D000236 Adenoma Benzo(a)pyrene 14.266695378
MESH:D000236 Adenoma Diethylnitrosamine 14.2610737359 6695378
MESH:D000236 Adenoma resveratrol 14.2615688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 15.3019061943 16434500 17620307 18056438 19052882 17162532
MESH:D018248 Adenoma, Liver Cell Phenobarbital 15.3017620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 15.3016434500
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.3415276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.5417306315 16712894
MESH:D000419 Albuminuria Doxorubicin 4.2121441931
MESH:D000544 Alzheimer Disease Ozone 6.2615513908
MESH:D000544 Alzheimer Disease resveratrol 6.2616162502 16183991
MESH:D000544 Alzheimer Disease sulindac sulfide 6.2618759972
MESH:D000686 Amyloidosis Diethylstilbestrol 4.1415469931
MESH:D000740 Anemia Fluorouracil 3.4116511603 17963324 15504547
MESH:D000743 Anemia, Hemolytic Quercetin 3.9217084956
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.7319183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.6315885639
MESH:D001169 Arthritis, Experimental resveratrol 6.6317115116
MESH:D001172 Arthritis, Rheumatoid Ozone 2.4715570426
MESH:D001249 Asthma Ozone 2.5317854713 16373670
MESH:D001260 Ataxia Telangiectasia Quercetin 4.6215336622
MESH:D050197 Atherosclerosis resveratrol 3.0616873680 17967414
MESH:D001327 Autoimmune Diseases Quercetin 4.0619761891
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.6611289319 1440618
MESH:D001778 Blood Coagulation Disorders pirinixic acid 2.8319483382
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.3414601052
MESH:D001859 Bone Neoplasms Paclitaxel 4.2415867366
MESH:D001862 Bone Resorption bisphenol A 3.5511985600
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.9817868700
MESH:D001930 Brain Injuries Progesterone 3.9115665606 15380490 15845082
MESH:D002545 Brain Ischemia resveratrol 3.9317600658
MESH:D001932 Brain Neoplasms Doxorubicin 3.5117150277
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 9.1620146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 9.1617123778
MESH:D001943 Breast Neoplasms Diethylnitrosamine 9.1617474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 9.1617129689 15324884
MESH:D001943 Breast Neoplasms docetaxel 9.1616264153 17369602 18628466 15692762 19526202 16495393 15567936
MESH:D001943 Breast Neoplasms Doxorubicin 9.1615993339 16115903 16595493 17369602 16826403 18628466 15692762 15939500 15567936 16264153 15634643 15136595 17426702 16096432 15994142 19526202 16322301 17983394 16935488 18695136 18382427 11325840 15668708 18234424
MESH:D001943 Breast Neoplasms Estradiol 9.1617289903 16675129 18497071 17261762 12948864 14630087 17018787 19861407
MESH:D001943 Breast Neoplasms Fluorouracil 9.1618357371 16110121 18608205 15136595 16595493 19217205 16557594
MESH:D001943 Breast Neoplasms Paclitaxel 9.1616115903 18323546 11325840 16244791 18223236 16273361 18234424 15136595
MESH:D001943 Breast Neoplasms Progesterone 9.1617614352 16175315 15562024
MESH:D001943 Breast Neoplasms Quercetin 9.1618628248
MESH:D001943 Breast Neoplasms resveratrol 9.1616393696 17651959 17534123
MESH:D016535 Bronchial Hyperreactivity Ozone 3.4018315731 16777450 18417511 14754758 15516495 17626835 19059883
MESH:D002100 Cachexia Ozone 4.3916183385
MESH:D002105 Cadmium Poisoning Quercetin 5.1816962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1116111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.4316124888 15673190 16011737 16097048 16192424 3786805 15721981 18705752 10355542 16050911 16227642 15700767
MESH:D002276 Carcinoid Tumor Doxorubicin 11.1516051944
MESH:D002276 Carcinoid Tumor Fluorouracil 11.1516051944
MESH:D002277 Carcinoma Fluorouracil 3.2917121937
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 37.8116705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 37.817296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 37.8112619106 21507988 12907637
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 37.8118788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 37.8117138121 18785209 16502159 19383236 17055752 19052882 20514400 16698587 16328049 18971187 3084413 16779866 19701751 11831363 18506893 20084675 16878318 18978308 20727157 21159647 20214788 16830150 18788625 19822196 19171122 19335982 16935385 19394651 19208518 10737359 19919837 20101231 17173139 18665156 10672840 19418558 19539802 17162532 16569478 3581430 18210153 20524982 18393292 20007298 17761372 16807293 17978847 20512989 16288022 18494052 20432363 20935162 18691550 16540662 16681979 19107877 18056438 19519916 17428255
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 37.8116924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 37.8116234567 18059187 16023760 17876044
MESH:D006528 Carcinoma, Hepatocellular Estradiol 37.8116924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 37.8117045692 16799960 17088986 18930000 16332177 17971768
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 37.8116313753
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 37.816705139 17173139 20935162 20007298 1701930
MESH:D006528 Carcinoma, Hepatocellular Quercetin 37.8119519916 12508355
MESH:D006528 Carcinoma, Hepatocellular resveratrol 37.8119321006 16227395
MESH:D006528 Carcinoma, Hepatocellular SC 560 37.8116391822
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 37.8117306315 15276417 16507464
MESH:D002278 Carcinoma in Situ bisphenol A 4.6317123778
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.2416675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung docetaxel 5.9011894018
MESH:D002289 Carcinoma, Non-Small-Cell Lung sulindac sulfide 5.9012391285
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.6117234771
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 13.997296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 13.9916201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 13.9918695887
MESH:D002292 Carcinoma, Renal Cell Vinblastine 13.991485588
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 16.6220419170
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 16.626189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 16.6216757204 16280240 18986760 17066447
MESH:D002294 Carcinoma, Squamous Cell resveratrol 16.6216227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 16.6218572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 16.6218922899
MESH:D006332 Cardiomegaly Quercetin 3.1219794523
MESH:D009202 Cardiomyopathies Doxorubicin 3.3016278810 15505089 17974986 17131338 17924179 17329180 17382496 15476868 17928571 17519947 16731534 16109756 15811867 17351982 17007740 17308081 16242529 18627295 16455267 16364871 16612575 16651473 16952015 16269455 15792986
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8216243910 17334414
MESH:D002318 Cardiovascular Diseases resveratrol 3.2315458977
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 28.066135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 28.067505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 28.0620889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 28.0612371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 28.0617174075 21159647 7505956 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 28.0618566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 28.0620056578 19524636
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.914080065
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.3919052882
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 17.079022650 19486331
MESH:D002779 Cholestasis Cyclosporine 17.0719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 17.0717681005 15861022 16919318 11677210 17110522 17333356 16105132
MESH:D002779 Cholestasis pirinixic acid 17.0719176532
MESH:D003092 Colitis resveratrol 3.7816474422
MESH:D003110 Colonic Neoplasms arsenite 10.3015037631
MESH:D003110 Colonic Neoplasms Fluorouracil 10.3017169374 16510598 17018589 15001691 17287894 17725105 16340194 18772588 17016597 17172411
MESH:D003110 Colonic Neoplasms irinotecan 10.3017725105 17287894
MESH:D003110 Colonic Neoplasms Quercetin 10.3017148506 11134977 15741050 17191121 19440933 19056647 16640504
MESH:D003110 Colonic Neoplasms resveratrol 10.3016338953
MESH:D015179 Colorectal Neoplasms Doxorubicin 9.8818259882 18802399
MESH:D015179 Colorectal Neoplasms Fluorouracil 9.8817594712 17695437 17016601 18509181 18448328 20501625 17255274 17454858 18288408 15148649 14970324 18802399 17094418 16524972 18949393 16303861 15289873 16391804 18383874 16282729 17401013 16331619
MESH:D015179 Colorectal Neoplasms irinotecan 9.8815273666 17159606 18259882 16391804 17454858 16303861 18509181
MESH:D015179 Colorectal Neoplasms Paclitaxel 9.8818802399
MESH:D015179 Colorectal Neoplasms Quercetin 9.8818852136 18095365
MESH:D015179 Colorectal Neoplasms resveratrol 9.8816550006
MESH:D015179 Colorectal Neoplasms Vinblastine 9.8818802399
MESH:D003327 Coronary Disease resveratrol 3.5216507316
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.2212952375 16002989
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.6718551238
MESH:D007644 Darier Disease Fluorouracil 4.4416733453
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.4812868966 11906362 8156756 14531868 18759878 8970840 2524372 11298694
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2618249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.173621924 2952479
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 7.6119496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 7.6116873680
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.1020387270
MESH:D003928 Diabetic Nephropathies Estradiol 8.0419279558
MESH:D003928 Diabetic Nephropathies resveratrol 8.0416286809
MESH:D003929 Diabetic Neuropathies Progesterone 4.1517187935
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 13.7621346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 13.768291058 6679447 18648102 16192314 6482804 18692083 9653073 18289764 1440618 11289319 7440962 9022650 9328219
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 13.763732212 21278145 6623471 10915739 4309450 2869522 3786805 19085960 6884620 16227642 10092053 16177239 15027814 7440962 11566570 17522070 15998439 15968718 7120509 7179309 9327722 19336974
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 13.7617851650
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 13.7619107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 13.7617416283
MESH:D004362 Drug Toxicity Doxorubicin 3.4118602426
MESH:D004421 Dystonia Phenobarbital 3.681851702
MESH:D004487 Edema pirinixic acid 9.7912083418
MESH:D004487 Edema resveratrol 9.798985016
MESH:D004487 Edema Tetradecanoylphorbol Acetate 9.7911698051 8273558 16716910 9599246 8113982 15177302 7812673
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 13.4412538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 13.4417692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 13.4417872969
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.3416402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 11.1816804899 15700306
MESH:D016889 Endometrial Neoplasms Doxorubicin 11.1817359293
MESH:D016889 Endometrial Neoplasms Estradiol 11.1818566989 11473722 19148513
MESH:D004715 Endometriosis Progesterone 3.4616134523
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.8018037988
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.5017923197
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.763659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.513922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.7120417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.256401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.917750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.673659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.7616302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 16.153581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 16.1520426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 16.1516530937
MESH:D004938 Esophageal Neoplasms docetaxel 16.1516337965
MESH:D004938 Esophageal Neoplasms Fluorouracil 16.1515173087 17638652 16337965 16481741 16785472
MESH:D004938 Esophageal Neoplasms Paclitaxel 16.1516481741
MESH:D005234 Fatty Liver arsenite 26.6118296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 26.6115959796 17595544 12631006 61145 12795759 16045604 19224547 16239168
MESH:D005234 Fatty Liver Cyclosporine 26.6119224547
MESH:D005234 Fatty Liver Diethylnitrosamine 26.6120387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 26.6115345470
MESH:D005234 Fatty Liver pirinixic acid 26.6120131406 19236843
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.4416002989 16611131 15751030 16513791 16534752
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.666705139
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.2319069698
MESH:D005355 Fibrosis arsenite 18.3618296743
MESH:D005355 Fibrosis Carbon Tetrachloride 18.3618705752
MESH:D005355 Fibrosis Cyclosporine 18.3612639820 12168785
MESH:D005355 Fibrosis Quercetin 18.3619474275
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 11.6316452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 11.6316452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.868708960
MESH:D005909 Glioblastoma Doxorubicin 6.6217150277
MESH:D005909 Glioblastoma Quercetin 6.6219804834
MESH:D005910 Glioma Fluorouracil 5.7016145905
MESH:D005910 Glioma Quercetin 5.7017643826
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.717505956
MESH:D006258 Head and Neck Neoplasms Doxorubicin 7.1215692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 7.1215162350 15102660 18337622
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.4720471113
MESH:D006331 Heart Diseases Doxorubicin 3.2418006777 16244371 16244372 12587719 16879835 16330681 14766674 16707910 16144979 18674790 16495754 17888722 17875725
MESH:D006333 Heart Failure Doxorubicin 6.3217481944
MESH:D006333 Heart Failure pirinixic acid 6.3220558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.5915692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0715720958
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.116705139
MESH:D006505 Hepatitis Carbon Tetrachloride 8.1119110552 19900420
MESH:D006529 Hepatomegaly Phenobarbital 7.3316109766
MESH:D006529 Hepatomegaly pirinixic acid 7.3318467677 16221962 19176532 19772884
MESH:D006558 Herpes Genitalis Estradiol 4.6715709030
MESH:D006561 Herpes Simplex resveratrol 3.8316876885
MESH:D006689 Hodgkin Disease Doxorubicin 10.7018501091 15147373 17606976
MESH:D006689 Hodgkin Disease sodium arsenite 10.7012676792
MESH:D006689 Hodgkin Disease Vinblastine 10.7018180244 18501091
MESH:D019584 Hot Flashes Estradiol 3.3917088409
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1816899240
MESH:D006937 Hypercholesterolemia resveratrol 3.6917188708
MESH:D006943 Hyperglycemia pirinixic acid 8.2320558911
MESH:D006943 Hyperglycemia Quercetin 8.2311834736 18262572
MESH:D006949 Hyperlipidemias resveratrol 3.7016873680
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 9.6815034207
MESH:D006965 Hyperplasia Diethylstilbestrol 9.6812960047 14722030
MESH:D006973 Hypertension Cyclosporine 4.8210903974
MESH:D006973 Hypertension Quercetin 4.8218356687
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.7415338365
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.0017488730
MESH:D007021 Hypospadias Diethylstilbestrol 10.0916002989
MESH:D007021 Hypospadias Ethinyl Estradiol 10.0916569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 10.3315869954
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 10.3317600658
MESH:D007246 Infertility Diethylstilbestrol 4.0215036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 5.8617937319
MESH:D007248 Infertility, Male sodium arsenite 5.8612646999 15346721
MESH:D007249 Inflammation Diethylnitrosamine 10.4818785209
MESH:D007249 Inflammation Progesterone 10.4815869954
MESH:D007249 Inflammation resveratrol 10.4816366677
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 10.488273558 15177302 7812673 11698051 7562506
MESH:D007251 Influenza, Human Quercetin 9.9916624496
MESH:D007251 Influenza, Human resveratrol 9.9916624496
MESH:D007333 Insulin Resistance bisphenol A 10.9716393666
MESH:D007333 Insulin Resistance Estradiol 10.9716393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 10.9716306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.668074119 9022650
MESH:D007627 Keloid Quercetin 4.6117086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0815604871
MESH:D007674 Kidney Diseases Cyclosporine 16.8618776723 10903974 8314463
MESH:D007674 Kidney Diseases Doxorubicin 16.8616775033 15699352 15369732
MESH:D007674 Kidney Diseases Estradiol 16.8615618244
MESH:D007674 Kidney Diseases Quercetin 16.8616962696
MESH:D007674 Kidney Diseases sodium arsenite 16.8620008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.8416707910
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 25.3916705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 25.396582329
MESH:D007680 Kidney Neoplasms Cyclosporine 25.3912371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 25.3915003126 14681315 16762066
MESH:D007680 Kidney Neoplasms Estradiol 25.3915610895
MESH:D007680 Kidney Neoplasms Fluorouracil 25.3916985049
MESH:D007859 Learning Disorders Diethylstilbestrol 3.7217184923
MESH:D007938 Leukemia Quercetin 2.9817468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.8016085563
MESH:D007951 Leukemia, Myeloid Hydroxyurea 4.7016532439
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.3516087638
MESH:D008080 Liposarcoma Paclitaxel 4.4917353645
MESH:D008103 Liver Cirrhosis arsenite 14.1418296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 14.1416239168 11408273 11903743 16943688 17174718 17157831 16221502 21278145 17334410
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 14.1418665156 19638242 20032147 18407596 18522880
MESH:D008103 Liver Cirrhosis Phenobarbital 14.1421047994
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.979327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 6.2117557913 12958196 15730626 13678700 17766677 18156304 16248980 18166357 15925388 15123356 17761835 18429990 12649538 14716833 17481882 18481824 16136751 18263696 17708605 18317297 16192424 15959796 17698563 12445421 18006644 15996030 14512876 17944888 18277467 16116963 15931870 15893842 12546737 16027843 12666154 15057751 15370692 18420326 12445418 14724832 18472094 12609069 17922224 18395095 12632514 15876570 18472332 17640975 15338365 17976157 16638106 12667390 15673190 17525996 18412020 18054572 17631135 17565644 17823541 20821823 18251166 16011737 18376398 18418968 18210741 18205269 14716496 12741479 14748882 11481614 12632512 16033810 17869086 18279442 12389079 17721639 14620537 12586293 16015684 16097048 12898905 10355542 15818738 15650968 18187930 17900296 18395914 18705752 17805973 18339082 17714472 15362042 15052691
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 6.2116439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.2114716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.2115474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 6.2112741479
MESH:D008107 Liver Diseases Carbon Tetrachloride 5.9516964402 17285989 15830285 15720792 16246199
MESH:D008107 Liver Diseases Diethylnitrosamine 5.9517034775
MESH:D008107 Liver Diseases Phenobarbital 5.9519363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8215123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.3816899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 39.737678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 39.739163691 18177683 15890375 2125692
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 39.7321137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 39.7319294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 39.7319073162 19426721 20492335 12771043 9163691 19294768 20583210 20452335 2422723 19638242 21167192 19254457 19551842 12112319 21047994 18977376 19833225 21071580 18754104 21278145 19850985 20101389 20434301 2862719 19996281 19499222 19255062 20137499 10737359 18644402 15885732 19690152 16942905 18648771 19256749 19812893 20405173 15175105 19427195 19642983 19090486 18978307 20118626 20501860
MESH:D008113 Liver Neoplasms Diethylstilbestrol 39.7316712894 15890375
MESH:D008113 Liver Neoplasms Fluorouracil 39.7318383874 17045692 16603448 15113037
MESH:D008113 Liver Neoplasms Phenobarbital 39.7319812893 19073162 15975961 8742319 21047994 19482888
MESH:D008113 Liver Neoplasms pirinixic acid 39.7315890375 16377806 20007298
MESH:D008113 Liver Neoplasms Quercetin 39.7318980244
MESH:D008113 Liver Neoplasms resveratrol 39.7320405173 19073162 19321006 19812893
MESH:D008113 Liver Neoplasms sodium arsenite 39.7315276417 16712894
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 29.392876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 29.39598648 1399818 3712494 6587162
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 29.398603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 29.3915583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 29.3919519916 18093689 18544905 18308698 19009564 21159647 18079962 18282651 19539802 2563599 9362446 17854601 18775883 19126423 16267830 16842330 19004024 3124819 17174075 17942915 18253720 18164116
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 29.3916842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 29.3917172636 2563599 1399818 6150874 18308698
MESH:D008114 Liver Neoplasms, Experimental Quercetin 29.3919519916
MESH:D008171 Lung Diseases Ozone 6.7219066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 6.7219095001
MESH:D055370 Lung Injury Ozone 3.5120417186
MESH:D008175 Lung Neoplasms Aflatoxin B1 16.8414755239
MESH:D008175 Lung Neoplasms arsenite 16.8416809336
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 16.8418816296 17053015 18569708 18520028 20464547 20135361 20869020 6695378 20064080
MESH:D008175 Lung Neoplasms Diethylnitrosamine 16.8420970405 20512841 21163286 6695378
MESH:D008175 Lung Neoplasms Doxorubicin 16.8417418594 6189445
MESH:D008175 Lung Neoplasms Fluorouracil 16.8415246190
MESH:D008175 Lung Neoplasms Ozone 16.848597069 7614698
MESH:D008175 Lung Neoplasms Quercetin 16.8416280456
MESH:D008175 Lung Neoplasms sodium arsenite 16.8417306315 17077188 16712894 19931552 15276417
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 16.8411807781
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.4415086387
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.7915166399
MESH:D008223 Lymphoma Diethylstilbestrol 6.9115700306
MESH:D008223 Lymphoma Doxorubicin 6.9116098063
MESH:D016393 Lymphoma, B-Cell resveratrol 3.9717088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 12.9817654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 12.9814749477
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 12.9814749477
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.2215621674
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.1516002989
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.8915688416
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 16.4115458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 16.4111408345 16891317 11807958 17203775
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 16.4117203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 16.418985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 16.418985016
MESH:D020149 Manganese Poisoning Estradiol 4.1219453300
MESH:D008545 Melanoma docetaxel 11.5912417787
MESH:D008545 Melanoma Doxorubicin 11.5916827129
MESH:D008545 Melanoma Paclitaxel 11.5916342250 12025231 12040289
MESH:D008545 Melanoma resveratrol 11.5917992120
MESH:D008545 Melanoma sodium arsenite 11.5919082730 16487513
MESH:D008545 Melanoma Vinblastine 11.5917761969 15577320 15577323 18176117 16248763 12374674 18505091 18332650 16809738 16432458
MESH:D008654 Mesothelioma Doxorubicin 2.9117638057
MESH:D008659 Metabolic Diseases resveratrol 4.0617112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4316801185
MESH:D008679 Metaplasia Ozone 4.7510496685
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.1815792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 7.6316381670
MESH:D009062 Mouth Neoplasms Fluorouracil 7.6316757204 18986760
MESH:D052016 Mucositis Doxorubicin 11.2417415656
MESH:D052016 Mucositis irinotecan 11.2417159606
MESH:D009101 Multiple Myeloma Paclitaxel 6.8014749477
MESH:D009101 Multiple Myeloma resveratrol 6.8017935668 16490592 14749477 16267019 17164350 17049120
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.5217962980
MESH:D009135 Muscular Diseases pirinixic acid 3.1616239165
MESH:D009203 Myocardial Infarction Doxorubicin 12.3015857846 19429709
MESH:D009203 Myocardial Infarction pirinixic acid 12.3019151258
MESH:D009203 Myocardial Infarction Quercetin 12.3019595682
MESH:D009203 Myocardial Infarction resveratrol 12.3016456233 16525036 17125593 16317513 17015251 17188708
MESH:D017202 Myocardial Ischemia resveratrol 3.7317125593 17015251
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.6316810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.6316411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 12.6319207477
MESH:D009205 Myocarditis resveratrol 4.4017322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.1217484760
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.5118551238 7678174
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 16.363581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 16.363581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 16.3618259882
MESH:D009362 Neoplasm Metastasis irinotecan 16.3618259882
MESH:D009362 Neoplasm Metastasis Paclitaxel 16.3615867366
MESH:D009369 Neoplasms Benzo(a)pyrene 17.4511141357
MESH:D009369 Neoplasms Diethylstilbestrol 17.4515313581
MESH:D009369 Neoplasms Fluorouracil 17.4518239605 18600527 16928823
MESH:D009369 Neoplasms pirinixic acid 17.4517405874
MESH:D009369 Neoplasms Quercetin 17.4515185748
MESH:D009369 Neoplasms sodium arsenite 17.4511559025
MESH:D009374 Neoplasms, Experimental resveratrol 8.088985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 8.0820056578
MESH:D009389 Neovascularization, Pathologic arsenite 8.9715738583
MESH:D009389 Neovascularization, Pathologic Estradiol 8.9717289903
MESH:D009401 Nephrosis Doxorubicin 4.4216899518 16636307
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.3118481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.3115640375 16889571
MESH:D009421 Nervous System Malformations bisphenol A 14.5316427766 11399458
MESH:D009421 Nervous System Malformations Diethylstilbestrol 14.5311399458
MESH:D009421 Nervous System Malformations Estradiol 14.5316427766 11399458
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 6.496679447
MESH:D009436 Neural Tube Defects sodium arsenite 6.4912854658
MESH:D009447 Neuroblastoma Doxorubicin 6.5315555623
MESH:D009447 Neuroblastoma irinotecan 6.538761367
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.5820387270
MESH:D019636 Neurodegenerative Diseases resveratrol 7.5817652729
MESH:D017599 Neuroectodermal Tumors irinotecan 4.388761367
MESH:D020078 Neurogenic Inflammation Quercetin 9.6117929310
MESH:D020078 Neurogenic Inflammation resveratrol 9.6117929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.7620387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.2016436463
MESH:D009503 Neutropenia Vinblastine 4.2517378895
MESH:D009765 Obesity pirinixic acid 1.7220558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 7.8716049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 7.876482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.663988306
MESH:D010014 Osteolysis Paclitaxel 4.6315867366
MESH:D010018 Osteomalacia Phenobarbital 4.0117016548
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 9.1219495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 9.1217513867
MESH:D012516 Osteosarcoma Doxorubicin 3.8315930896
MESH:D010049 Ovarian Diseases bisphenol A 4.6311985600
MESH:D010051 Ovarian Neoplasms Estradiol 13.7019401270
MESH:D010051 Ovarian Neoplasms Paclitaxel 13.7011161223
MESH:D010051 Ovarian Neoplasms Progesterone 13.7016525653 17393432
MESH:D010051 Ovarian Neoplasms Quercetin 13.7019005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 13.7015276417 17306315
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 14.8916540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 14.8916500647 16929163 15113037 19003803
MESH:D010190 Pancreatic Neoplasms Phenobarbital 14.8916965848
MESH:D010190 Pancreatic Neoplasms Quercetin 14.8916965848
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 14.8915976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3611578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 8.247296757
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 8.2418404319 12065085 8330346 18922899
MESH:D010538 Peritonitis Ozone 3.7916369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.116228378
MESH:D003557 Phyllodes Tumor Doxorubicin 4.8017983394
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.8114722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.3215687265 16977796
MESH:D010997 Pleural Neoplasms Doxorubicin 4.8017638057
MESH:D011014 Pneumonia Ozone 4.0418007984 18929643 18381685
MESH:D011230 Precancerous Conditions Cyclosporine 19.4412371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 19.442563599
MESH:D011230 Precancerous Conditions Phenobarbital 19.442563599
MESH:D011230 Precancerous Conditions Quercetin 19.4419056647
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 14.3610548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 14.3617184923
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 14.3616679765
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.5020887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.5020887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 4.8017292933
MESH:D011471 Prostatic Neoplasms bicalutamide 4.8018487222 17914592 15638997 19240160 19011039
MESH:D011471 Prostatic Neoplasms bisphenol A 4.8016740699
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 4.8017136230 15046698 15846301
MESH:D011471 Prostatic Neoplasms docetaxel 4.8018824434 16644109 19103299 16520278
MESH:D011471 Prostatic Neoplasms Doxorubicin 4.8015749863 15897917 16888761 18437689 16868541 16729912
MESH:D011471 Prostatic Neoplasms Estradiol 4.8016740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 4.8019082440 18626508
MESH:D011471 Prostatic Neoplasms Paclitaxel 4.8016356831 17136230 17172428 16729912
MESH:D011471 Prostatic Neoplasms Quercetin 4.8017292933 14715546
MESH:D011471 Prostatic Neoplasms resveratrol 4.8016731767 17675339 15767336 17804756 17718901 17636462
MESH:D011471 Prostatic Neoplasms sodium arsenite 4.8016039940
MESH:D011537 Pruritus Ethinyl Estradiol 2.9615861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 4.1312752131
MESH:D011565 Psoriasis Cyclosporine 2.1016882103
MESH:D011629 Puberty, Precocious bisphenol A 4.4310548101
MESH:D012004 Rectal Neoplasms Fluorouracil 3.7118286688 16160472 18722050 15538739
MESH:D051437 Renal Insufficiency Doxorubicin 3.8817922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.2216325855
MESH:D015427 Reperfusion Injury pirinixic acid 5.9819058328
MESH:D015427 Reperfusion Injury resveratrol 5.9817058453 16314181 16317513 17520802 15827377
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.113692021
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7318045962
MESH:D012509 Sarcoma Doxorubicin 3.6816767912 17203757 15625365 18313854 17710206 15675481
MESH:D012512 Sarcoma, Ewing's Doxorubicin 3.9114601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.4417846226
MESH:D012554 Schistosomiasis japonica Quercetin 5.1816862918
MESH:D012640 Seizures 2,6-dinitrotoluene 5.1318551238
MESH:D012640 Seizures Phenobarbital 5.133137016 11442880 4039156 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.476407741
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 16.1119755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 16.1115692506
MESH:D012878 Skin Neoplasms resveratrol 16.118985016 15837718
MESH:D012878 Skin Neoplasms sodium arsenite 16.1119524636 18572023
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 16.118330346 12065085 18404319 8985016 11807781
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.2216767912 17203757 15625365
MESH:D013088 Spermatocele Diethylstilbestrol 10.5116709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 10.5116709447
MESH:D013119 Spinal Cord Injuries Progesterone 3.9316503802 15862959
MESH:D016135 Spinal Dysraphism sodium arsenite 3.5312854658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 7.772093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 7.7718456281
MESH:D013274 Stomach Neoplasms docetaxel 7.7716557585
MESH:D013274 Stomach Neoplasms Fluorouracil 7.7719015929 16424979 19084572 18396642 17172411 17522103 17498489 18567086 16951190 15786421
MESH:D013274 Stomach Neoplasms irinotecan 7.7715723263
MESH:D013274 Stomach Neoplasms Paclitaxel 7.7718506536 18396642
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.1716321402
MESH:D019966 Substance-Related Disorders bisphenol A 3.6316684133 16045194
MESH:D024801 Tauopathies Paclitaxel 4.4616930453
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2911994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8615669648
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 14.916582329 3712494 6587162 7505956 1399818
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 14.917505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 14.9116010429 17909728
MESH:D013964 Thyroid Neoplasms Phenobarbital 14.911399818
MESH:D013978 Tibial Fractures Estradiol 4.3219048282
MESH:D014062 Tongue Neoplasms Fluorouracil 8.9716280240
MESH:D014062 Tongue Neoplasms resveratrol 8.9716227395
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 21.8916049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 21.898074119
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 21.8917053015
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 21.8916452187 17306315 16712894
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 21.8917653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 21.8916720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 21.8916452187 16712894 11723127 17306315
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.9610091137
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 20.1416175088
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 20.1416803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 20.1417473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 20.1411813266
MESH:D014591 Uterine Diseases bisphenol A 12.6114652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 12.6114652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 20.1815809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 20.1814692618
MESH:D014594 Uterine Neoplasms resveratrol 20.1817044934
MESH:D014594 Uterine Neoplasms sulindac sulfide 20.1818645019
MESH:D014605 Uveitis Cyclosporine 3.621336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 10.0916513791 16002989
MESH:D014625 Vaginal Neoplasms Vinblastine 10.0915577323
MESH:D014652 Vascular Diseases sodium arsenite 4.0717056641
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2214671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 9.1917678736 16364871 17334414 17638931
MESH:D018487 Ventricular Dysfunction, Left resveratrol 9.1917488730
MESH:D014985 Xerophthalmia Cyclosporine 4.0817120751
Pathway ID Pathway Name
REACT:8017 APC-Cdc20 mediated degradation of Nek2A
REACT:6850 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
KEGG:04110 Cell cycle
REACT:1538 Cell Cycle Checkpoints
REACT:152 Cell Cycle, Mitotic
REACT:383 DNA Replication
KEGG:04114 Oocyte meiosis
KEGG:04914 Progesterone-mediated oocyte maturation
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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