AutismKB 2.0

Annotation Detail for MAGEA4


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Basic Information Top
Gene Symbol:MAGEA4 ( CT1.4,MAGE-41,MAGE-X2,MAGE4,MAGE4A,MAGE4B,MGC21336 )
Gene Full Name: melanoma antigen family A, 4
Band: Xq28
Quick LinksEntrez ID:4103; OMIM: 300175; Uniprot ID:MAGA4_HUMAN; ENSEMBL ID: ENSG00000147381; HGNC ID: 6802
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1702Skin tumor
1831Prostate cancer
1945Papillary cancer
1976Squamous cell cancer
2066Lung cancer
2125Bladder cancer
1855Prostatic hypertrophy, Benign
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C014347 decitabine decitabine affects the expression of MAGEA4 mRNAaffects expression 18791715
C014347 decitabine decitabine results in increased expression of MAGEA4 mRNAincreases expression 19401350
D005472 Fluorouracil MAGEA4 protein affects the susceptibility to Fluorouracilaffects response to substance 16217747
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Fluorouracil 2.5117638652
MESH:D000740 Anemia Fluorouracil 4.2217963324 15504547 16511603
MESH:D001943 Breast Neoplasms decitabine 2.3418320071 19208741
MESH:D001943 Breast Neoplasms Fluorouracil 2.3416110121 19217205 16557594 15136595 18608205 18357371 16595493
MESH:D002276 Carcinoid Tumor Fluorouracil 5.7416051944
MESH:D002277 Carcinoma Fluorouracil 3.9717121937
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 2.1217088986 16332177 16799960 18930000 17971768 17045692
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 3.2018695887
MESH:D002294 Carcinoma, Squamous Cell decitabine 5.2019215824
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 5.2018986760 16757204 16280240 17066447
MESH:D003110 Colonic Neoplasms decitabine 4.0917616700
MESH:D003110 Colonic Neoplasms Fluorouracil 4.0917725105 16340194 17169374 17172411 17016597 17287894 15001691 18772588 16510598 17018589
MESH:D015179 Colorectal Neoplasms decitabine 2.7218981723
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.7216331619 17016601 17454858 18288408 17401013 14970324 20501625 17094418 18509181 18949393 18383874 15289873 15148649 16391804 18802399 16524972 16303861 18448328 17594712 17255274 17695437 16282729
MESH:D007644 Darier Disease Fluorouracil 5.6816733453
MESH:D004701 Endocrine Gland Neoplasms decitabine 6.1919294695
MESH:D004938 Esophageal Neoplasms Fluorouracil 2.5416481741 16785472 16337965 17638652 15173087
MESH:D005910 Glioma Fluorouracil 3.0216145905
MESH:D006258 Head and Neck Neoplasms decitabine 8.9519215824
MESH:D006258 Head and Neck Neoplasms Fluorouracil 8.9515162350 15102660 18337622
MESH:D007248 Infertility, Male decitabine 3.5117581917
MESH:D007680 Kidney Neoplasms Fluorouracil 3.7416985049
MESH:D007938 Leukemia decitabine 3.2718980019 19235587
MESH:D007951 Leukemia, Myeloid decitabine 4.5517236224 18454857 19117987
MESH:D015470 Leukemia, Myeloid, Acute decitabine 2.4418460780 18704418 19387464 18206229 17679729 19010910
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 6.5318055864
MESH:D008113 Liver Neoplasms Fluorouracil 2.6216603448 15113037 18383874 17045692
MESH:D008175 Lung Neoplasms Fluorouracil 2.0115246190
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 5.6815086387
MESH:D008223 Lymphoma decitabine 3.7619470736
MESH:D008545 Melanoma decitabine 2.2916505122 17785578
MESH:D009062 Mouth Neoplasms Fluorouracil 4.0218986760 16757204
MESH:D009101 Multiple Myeloma decitabine 3.6918172295
MESH:D009190 Myelodysplastic Syndromes decitabine 3.6219157545 16882708 19010910 18608210
MESH:D009369 Neoplasms decitabine 5.9519116145 17925555 19470736
MESH:D009369 Neoplasms Fluorouracil 5.9518239605 18600527 16928823
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.7516436463
MESH:D010051 Ovarian Neoplasms decitabine 2.7619259094 19331143
MESH:D010190 Pancreatic Neoplasms decitabine 5.9119294695
MESH:D010190 Pancreatic Neoplasms Fluorouracil 5.9116500647 16929163 15113037 19003803
MESH:D055728 Primary Myelofibrosis decitabine 5.4917616702
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.3418626508 19082440
MESH:D012004 Rectal Neoplasms Fluorouracil 4.4818722050 18286688 16160472 15538739
MESH:D012208 Rhabdomyosarcoma decitabine 5.0119155313
MESH:D013274 Stomach Neoplasms decitabine 2.7119037991
MESH:D013274 Stomach Neoplasms Fluorouracil 2.7115786421 17172411 17522103 17498489 16424979 19084572 18396642 19015929 18567086 16951190
MESH:D013964 Thyroid Neoplasms decitabine 3.7117967635
MESH:D014062 Tongue Neoplasms Fluorouracil 4.5016280240
MESH:D001749 Urinary Bladder Neoplasms decitabine 2.8619087683 17616700
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 4.3816803524
MESH:D014604 Uveal Neoplasms decitabine 5.9817785578
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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