AutismKB 2.0

Annotation Detail for MAGEA8


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Basic Information Top
Gene Symbol:MAGEA8 ( CT1.8,MAGE8,MGC2182 )
Gene Full Name: melanoma antigen family A, 8
Band: Xq28
Quick LinksEntrez ID:4107; OMIM: 300341; Uniprot ID:MAGA8_HUMAN; ENSEMBL ID: ENSG00000156009; HGNC ID: 6806
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D020849 Raloxifene Raloxifene affects the expression of MAGEA8 mRNAaffects expression 14699072
D020849 Raloxifene [Raloxifene co-treated with ESR2 protein] results in decreased expression of MAGEA8 mRNAaffects cotreatment|decreases expression 19059307
D013629 Tamoxifen Tamoxifen affects the expression of MAGEA8 mRNAaffects expression 14699072
D013629 Tamoxifen [Tamoxifen co-treated with ESR2 protein] results in decreased expression of MAGEA8 mRNAaffects cotreatment|decreases expression 19059307
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 5.6214745880
MESH:D000419 Albuminuria Raloxifene 5.2717308373 17451421
MESH:D000544 Alzheimer Disease Raloxifene 2.6215800139
MESH:D001930 Brain Injuries Raloxifene 5.2416580743
MESH:D001943 Breast Neoplasms Raloxifene 2.2716912660 17242785 17893378 15775269 15758505 17049068 15572757 17261762 17440819 17952589 17595753 16837676
MESH:D001943 Breast Neoplasms Tamoxifen 2.2719410462 11161223 19244106 19084267 18425577 19142967 16273361 20135344 19155303 15668708 20065188 18815881 19487384 16202921 17049068 16873071 18629630 18855134 19289846 19115204 16818667 20544844 17261762 18351453 19288272 15565566 21138602 19189210 19066611 19189212 20390343 17893378 18821012 19221464 18997820 19011961 19103187 21152245 17242785 19200415 18984771 17440819 20005174 19059307 20859285
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 5.2719066611
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 1.8616924424
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 11.2317572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 11.2317572228
MESH:D002318 Cardiovascular Diseases Raloxifene 3.7715775269
MESH:D003072 Cognition Disorders Raloxifene 5.3815800139
MESH:D003711 Demyelinating Diseases Tamoxifen 5.1319031437
MESH:D003865 Depressive Disorder, Major Raloxifene 4.6317474826
MESH:D003928 Diabetic Nephropathies Raloxifene 10.6317308373 15920148 17451421
MESH:D003928 Diabetic Nephropathies Tamoxifen 10.6319279558
MESH:D004487 Edema Raloxifene 3.8815860553
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 11.5915845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 11.5919031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.3417893378 20544844 16202921 19155303
MESH:D005234 Fatty Liver Raloxifene 9.8717473493
MESH:D005234 Fatty Liver Tamoxifen 9.8719224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.5016709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 5.4114745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 5.0719069698
MESH:D006331 Heart Diseases Raloxifene 3.8611110106
MESH:D006973 Hypertension Raloxifene 3.0015787275 17577099
MESH:D007249 Inflammation Tamoxifen 2.5719457130
MESH:D007680 Kidney Neoplasms Tamoxifen 3.4718625569
MESH:D007889 Leiomyoma Raloxifene 5.1016973256
MESH:D008064 Lipidoses Tamoxifen 3.5017567588 15342952
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 1.7518564211
MESH:D008113 Liver Neoplasms Tamoxifen 2.3516684651
MESH:D008175 Lung Neoplasms Tamoxifen 1.7518625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.6419428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.9111731420 19196723 14580682 19196722 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 5.6219453300
MESH:D008545 Melanoma Tamoxifen 1.9319393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 5.0715990972
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 6.6215863610
MESH:D009101 Multiple Myeloma Raloxifene 3.7816497877
MESH:D009232 Myxoma Raloxifene 6.6216343187
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.7019393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.6319410462
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 5.0719189210 19200415 19196722
MESH:D010024 Osteoporosis Raloxifene 3.6619059307 17882678 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.8317823083 17893378 15579764 15758505
MESH:D011471 Prostatic Neoplasms Raloxifene 3.2716220300 15731164 16536755
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.2715067354
MESH:D011693 Purpura Raloxifene 6.6215770314
MESH:D013088 Spermatocele Tamoxifen 5.3616709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.9219457130
MESH:D020521 Stroke Raloxifene 4.2316837676
MESH:D013978 Tibial Fractures Raloxifene 6.2819048282
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 5.7417572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 5.7416712894 8653321 17572228
MESH:D054556 Venous Thromboembolism Raloxifene 6.2816837676
MESH:D014846 Vulvar Neoplasms Raloxifene 6.6216343187
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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