AutismKB 2.0

Annotation Detail for MAOA


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Basic Information Top
Gene Symbol:MAOA ( - )
Gene Full Name: monoamine oxidase A
Band: Xp11.3
Quick LinksEntrez ID:4128; OMIM: 309850; Uniprot ID:AOFA_HUMAN; ENSEMBL ID: ENSG00000189221; HGNC ID: 6833
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-6342noradrenaline and adrenaline degradation
PWY-6402superpathway of melatonin degradation
PWY-6313serotonin degradation
PWY-6399melatonin degradation II
PWY6666-2dopamine degradation
PWY-6318phenylalanine degradation IV (mammalian, via side chain)
Pathway IDPathway Name
hsa00360Phenylalanine metabolism
hsa00380Tryptophan metabolism
hsa00982Drug metabolism - cytochrome P450
hsa00330Arginine and proline metabolism
hsa00350Tyrosine metabolism
hsa01100Metabolic pathways
hsa00340Histidine metabolism
hsa00260Glycine, serine and threonine metabolism
Pathway IDPathway Name
Synaptic Transmission
Biological oxidations
No data
Pathway IDPathway Name
P00001Adrenaline and noradrenaline biosynthesis
P043725-Hydroxytryptamine degredation
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1836Panic disorder
1856Obesity
1866Sudden infant death syndrome
1870Drug abuse
1907Depression
1923Generalized anxiety disorder
1944Breast cancer
1983Down syndrome
2006Anorexia nervosa
2045Bipolar disorder
2124Autistic disorder
2144Fibromyalgia
2147Neurotic disorder
2221Behavior disease
Desease Name
bipolar disorder
neuroticism
Parkinson's disease
personality traits
restless legs syndrome
personality
CHEMDEPENDENCY
heroin addiction
ADHD
alcoholism personality disorders
bipolar affective disorder
Alzheimer's disease
thrombocyte MAO activity
PSYCH
Tourette syndrome
Depression, Postpartum
behavioural traits
aggression, impulsivity, and central nervous system serotonergic responsivity
alcoholism
body mass obesity
depressed suicide
early onset alcoholism/substance abuse.
anxiety disorder
pathologic gambling
antisocial personality disorder
attention-deficit hyperactivity disorder
depression sleep disorders
depressive disorder, major
personality disorders
alcohol abuse
NEUROLOGICAL
attention deficit hyperactivity disorder
Fibromyalgia
schizophrenia
METABOLIC
smoking behavior
obesity
depression
major depressive disorder
panic disorder
Autism
sleep disorders
cytogenetic studies
Desease Name
Smoking behavior
Desease Name
Brunner syndrome
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of MAOA mRNAdecreases expression 19933214
C492672 3-methoxymethyl-7-(4,4,4-trifluorobutoxy)-3,3a,4,5-tetrahydro-1,3-oxazolo(3,4-a)quinolin-1-one 3-methoxymethyl-7-(4,4,4-trifluorobutoxy)-3,3a,4,5-tetrahydro-1,3-oxazolo(3,4-a)quinolin-1-one results in decreased activity of MAOA proteindecreases activity 15178694
D000082 Acetaminophen Acetaminophen affects the expression of MAOA mRNAaffects expression 17562736
C067527 aluminum maltolate aluminum maltolate results in increased activity of MAOA proteinincreases activity 16087240
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MAOA mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of MAOA mRNAincreases expression 15761015
D016589 Astemizole Astemizole results in decreased expression of MAOA mRNAdecreases expression 20221588
D001280 Atrazine [Atrazine co-treated with Diuron co-treated with isoproturon] affects the expression of MAOA mRNAaffects cotreatment|affects expression 15245914
C090014 befloxatone befloxatone results in decreased activity of MAOA proteindecreases activity 15178694
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of MAOA mRNAincreases expression 20127859
C006780 bisphenol A bisphenol A results in increased expression of MAOA mRNAincreases expression 11331657
C038213 brofaromine brofaromine results in decreased activity of MAOA proteindecreases activity 15178694
D002211 Capsaicin Capsaicin results in decreased expression of MAOA mRNAdecreases expression 18783367
D002220 Carbamazepine Carbamazepine results in increased expression of MAOA mRNAincreases expression 17112801
D002395 Catecholamines MAOA protein affects the metabolism of Catecholaminesaffects metabolic processing 15946989
C026234 cimoxatone cimoxatone results in decreased activity of MAOA proteindecreases activity 15178694
D003010 Clorgyline Clorgyline results in decreased activity of MAOA proteindecreases activity 18783367
19691856
D003474 Curcumin Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MAOA mRNA]decreases expression|decreases reaction 18200517
D003520 Cyclophosphamide Cyclophosphamide results in increased expression of MAOA mRNAincreases expression 17403535
D016572 Cyclosporine Cyclosporine results in decreased expression of MAOA mRNAdecreases expression 20106945
C017160 cypermethrin cypermethrin results in decreased activity of MAOA proteindecreases activity 8385837
D003907 Dexamethasone Dexamethasone results in increased expression of MAOA mRNAincreases expression 15679045
15946989
D003907 Dexamethasone Dexamethasone results in increased expression of MAOA proteinincreases expression 15946989
15679045
D003907 Dexamethasone Mifepristone inhibits the reaction [Dexamethasone results in increased expression of MAOA mRNA]decreases reaction|increases expression 15946989
D003907 Dexamethasone Plicamycin inhibits the reaction [Dexamethasone results in increased expression of MAOA mRNA]decreases reaction|increases expression 15946989
D002945 Cisplatin Cisplatin results in increased expression of MAOA mRNAincreases expression 15471895
15464296
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MAOA mRNAaffects cotreatment|decreases expression 18544905
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of MAOA mRNAincreases expression 10811566
11331657
D004054 Diethylstilbestrol Diethylstilbestrol results in decreased expression of MAOA mRNAdecreases expression 15289156
D004237 Diuron [Atrazine co-treated with Diuron co-treated with isoproturon] affects the expression of MAOA mRNAaffects cotreatment|affects expression 15245914
D004298 Dopamine MAOA protein results in increased metabolism of Dopamineincreases metabolic processing 18361446
D004837 Epinephrine MAOA protein results in increased metabolism of Epinephrineincreases metabolic processing 18361446
D004958 Estradiol Estradiol results in increased expression of MAOA mRNAincreases expression 10811566
11331657
D004958 Estradiol [Progesterone co-treated with Estradiol] results in increased expression of MAOA mRNAaffects cotreatment|increases expression 17404688
D004958 Estradiol Estradiol results in decreased expression of MAOA mRNAdecreases expression 15289156
D004958 Estradiol Estradiol results in decreased expression of MAOA mRNAdecreases expression 20068009
C017690 fenvalerate fenvalerate results in decreased activity of MAOA proteindecreases activity 8385837
D019833 Genistein Genistein results in increased expression of MAOA mRNAincreases expression 11331657
D019833 Genistein Genistein results in decreased expression of MAOA mRNAdecreases expression 15289156
D018684 Glycine Agents Glycine Agents affects the expression of MAOA mRNAaffects expression 15245914
D006246 Harmaline Harmaline results in decreased activity of MAOA proteindecreases activity 15178694
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of MAOA mRNAaffects cotreatment|increases expression 17183730
D006838 Hydrocarbons Hydrocarbons results in increased expression of MAOA mRNAincreases expression 15245914
D012701 Serotonin MAOA gene polymorphism results in increased abundance of Serotoninincreases abundance 18405062
D012701 Serotonin Serotonin results in increased activity of MAOA proteinincreases activity 17561096
D012701 Serotonin MAOA protein results in increased metabolism of Serotoninincreases metabolic processing 18361446
D019266 Iron, Dietary Iron, Dietary affects the expression of MAOA mRNAaffects expression 15637178
D007529 Isoflavones Isoflavones results in decreased expression of MAOA mRNAdecreases expression 17374662
C028904 isoproturon [Atrazine co-treated with Diuron co-treated with isoproturon] affects the expression of MAOA mRNAaffects cotreatment|affects expression 15245914
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MAOA mRNAaffects cotreatment|decreases expression 18544905
D008694 Methamphetamine Methamphetamine results in increased expression of MAOA mRNAincreases expression 19149911
D008743 Methyl Parathion Methyl Parathion results in increased activity of MAOA proteinincreases activity 11495289
D015741 Metribolone Metribolone promotes the reaction [NDRG1 protein binds to MAOA protein]affects binding|increases reaction 17220478
D015735 Mifepristone Mifepristone inhibits the reaction [Dexamethasone results in increased expression of MAOA mRNA]decreases reaction|increases expression 15946989
D020912 Moclobemide Moclobemide results in decreased activity of MAOA proteindecreases activity 15178694
D009002 Monomethylhydrazine Monomethylhydrazine results in increased activity of MAOA proteinincreases activity 8583353
C029938 nickel sulfate nickel sulfate results in increased expression of MAOA mRNAincreases expression 16780908
D009638 Norepinephrine MAOA protein results in increased metabolism of Norepinephrineincreases metabolic processing 18361446
C076029 olanzapine olanzapine results in increased expression of MAOA mRNAincreases expression 15964593
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of MAOA mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital affects the expression of MAOA mRNAaffects expression 19136022
D010634 Phenobarbital Phenobarbital results in increased expression of MAOA mRNAincreases expression 19482888
C006253 pirinixic acid pirinixic acid affects the expression of MAOA mRNAaffects expression 19136022
C006253 pirinixic acid pirinixic acid results in increased expression of MAOA mRNAincreases expression 18301758
D008926 Plicamycin Plicamycin inhibits the reaction [Dexamethasone results in increased expression of MAOA mRNA]decreases reaction|increases expression 15946989
D011344 Procarbazine Procarbazine results in increased activity of MAOA proteinincreases activity 8583353
D011374 Progesterone [Progesterone co-treated with Estradiol] results in increased expression of MAOA mRNAaffects cotreatment|increases expression 17404688
D011374 Progesterone Progesterone results in increased expression of MAOA mRNAincreases expression 17404688
D011374 Progesterone Progesterone results in decreased expression of MAOAdecreases expression 17510236
D017382 Reactive Oxygen Species [Tyramine results in increased activity of MAOA protein] promotes the reaction [[Reactive Oxygen Species results in increased activity of MMP2 protein] which results in increased activity of SMPD3 protein]increases activity|increases reaction 17561096
D020280 Sertraline MAOA protein results in decreased amination of and results in increased metabolism of Sertralinedecreases amination|increases metabolic processing 15547048
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of MAOA mRNAdecreases expression 20106945
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of MAOA mRNAdecreases expression 19933214
C010798 toloxatone toloxatone results in decreased activity of MAOA proteindecreases activity 15178694
D014302 Trinitrobenzenesulfonic Acid Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of MAOA mRNA]decreases expression|decreases reaction 18200517
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in decreased expression of MAOA mRNAdecreases expression 18200517
D014439 Tyramine [Tyramine results in increased activity of MAOA protein] promotes the reaction [[Reactive Oxygen Species results in increased activity of MMP2 protein] which results in increased activity of SMPD3 protein]increases activity|increases reaction 17561096
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of MAOA mRNAaffects cotreatment|increases expression 17183730
D015029 Zeranol Zeranol results in increased expression of MAOA mRNAincreases expression 11331657
10811566
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Capsaicin 20.0418926900
MESH:D000014 Abnormalities, Drug-Induced Carbamazepine 20.048986270
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 20.046195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 20.0415322242 11752688 14514962
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 20.048875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.3619490988
MESH:D000138 Acidosis Ammonium Chloride 2.9318287403
MESH:D058186 Acute Kidney Injury Capsaicin 7.2618460982
MESH:D058186 Acute Kidney Injury Cisplatin 7.2612690470 17670903 15814532
MESH:D055371 Acute Lung Injury nickel sulfate 7.2016100012 19131640 12718980 11954676
MESH:D055371 Acute Lung Injury pirinixic acid 7.2018653653
MESH:D000230 Adenocarcinoma arsenic trioxide 11.2911798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 11.2920127859 20464547
MESH:D000230 Adenocarcinoma Cisplatin 11.2911798837 17638652
MESH:D000230 Adenocarcinoma Estradiol 11.2911473722
MESH:D000230 Adenocarcinoma Genistein 11.2911473722
MESH:D000236 Adenoma Benzo(a)pyrene 5.306695378
MESH:D000236 Adenoma Diethylnitrosamine 5.306695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 19.6916434500 19052882 17162532 19061943 18056438 17620307
MESH:D018248 Adenoma, Liver Cell Phenobarbital 19.6917620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 19.6916434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 19.6916835633
MESH:D000303 Adrenal Cortex Diseases Catecholamines 6.676895166
MESH:D000382 Agricultural Workers' Diseases Atrazine 7.2711874814
MESH:D000382 Agricultural Workers' Diseases cypermethrin 7.2716487989
MESH:D019973 Alcohol-Related Disorders Curcumin 4.4417887948
MESH:D000505 Alopecia Capsaicin 8.2817569567
MESH:D000505 Alopecia Isoflavones 8.2817569567
MESH:D000544 Alzheimer Disease Curcumin 2.4615590663
MESH:D000550 Amblyopia Valproic Acid 4.5917688650
MESH:D000686 Amyloidosis Diethylstilbestrol 3.8815469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.4011748828
MESH:D000799 Angioedema Acetaminophen 9.8810982225
MESH:D000799 Angioedema Astemizole 9.882883202
MESH:D001008 Anxiety Disorders Sertraline 7.6918822694
MESH:D001008 Anxiety Disorders Valproic Acid 7.6917497229
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.4519183758
MESH:D001161 Arteriosclerosis Cyclophosphamide 3.9815014928
MESH:D001169 Arthritis, Experimental Dexamethasone 3.1217659584
MESH:D001172 Arthritis, Rheumatoid Curcumin 2.5616807698
MESH:D050197 Atherosclerosis Curcumin 2.9218704882
MESH:D001321 Autistic Disorder marker/mechanism 12919132 18361446
MESH:D001321 Autistic Disorder Acetaminophen 4.0118445737
MESH:D001321 Autistic Disorder Norepinephrine 4.018570775
MESH:D001321 Autistic Disorder olanzapine 4.0118685284 17069543
MESH:D001321 Autistic Disorder Serotonin 4.0117157402 15132762 19221690 8570775 18361446 18405062 18062943
MESH:D001321 Autistic Disorder Sertraline 4.0118775368
MESH:D001321 Autistic Disorder Valproic Acid 4.0119232924 15238991 18316065 18985861 16609825 18558336 18940202 20603192 17157402 17507914 18177632 19460635 18775368 18396377 17688650
MESH:D001327 Autoimmune Diseases Curcumin 3.8819761891
MESH:D001714 Bipolar Disorder Carbamazepine 6.3420046352 17594078
MESH:D001714 Bipolar Disorder Valproic Acid 6.3420046352 17594078
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 11.9916206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 11.9919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 11.9912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.1515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 6.5815746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 6.588888407
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.2414601052
MESH:D001862 Bone Resorption bisphenol A 3.3011985600
MESH:D001919 Bradycardia Capsaicin 9.1518207255
MESH:D001919 Bradycardia Serotonin 9.158112388
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.6917868700
MESH:D001930 Brain Injuries Progesterone 3.6415845082 15380490 15665606
MESH:D002545 Brain Ischemia Capsaicin 8.4819211983
MESH:D002545 Brain Ischemia Curcumin 8.4816770732
MESH:D001932 Brain Neoplasms Curcumin 3.3917596214
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 8.3720146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 8.3717123778
MESH:D001943 Breast Neoplasms Cisplatin 8.3718382427 19526202
MESH:D001943 Breast Neoplasms Curcumin 8.3718593918 16243823 19250217 18462866
MESH:D001943 Breast Neoplasms Cyclophosphamide 8.3711325840 12006526 15093573 15136595 18234424 16978400 17388661 18323546 17020986
MESH:D001943 Breast Neoplasms Diethylnitrosamine 8.3717474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 8.3717129689 15324884
MESH:D001943 Breast Neoplasms Estradiol 8.3716675129 19861407 12948864 18497071 17289903 14630087 17018787 17261762
MESH:D001943 Breast Neoplasms Genistein 8.3716873071 17200150 16541309
MESH:D001943 Breast Neoplasms Procarbazine 8.3711921183
MESH:D001943 Breast Neoplasms Progesterone 8.3717614352 15562024 16175315
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 8.3720435547
OMIM:300615 BRUNNER SYNDROME marker/mechanism
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.7411589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.8316111702
MESH:D002277 Carcinoma Curcumin 6.5918593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.5916835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 16.983084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 16.9815073043 14691202 11135700 16217749 15553829
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 16.9817982673
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 16.9819701751
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 16.9819701751 19107877 17761372 20935162 18210153 20101231 11831363 16540662 20524982 16830150 17055752 19383236 17173139 19418558 17978847 10672840 19919837 18494052 16288022 18691550 16569478 16698587 16502159 18056438 19052882 20007298 3084413 21159647 17138121 20512989 20214788 18971187 16935385 19335982 18393292 3581430 19171122 16681979 20727157 16779866 18788625 20432363 16328049 18665156 19208518 18978308 19539802 10737359 18506893 19822196 16878318 17162532 16807293 20514400 19519916 18785209 19394651 17428255 20084675
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 16.9815948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Estradiol 16.9816924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 16.9816924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 16.9817173139 20007298 6705139 20935162 1701930
MESH:D002278 Carcinoma in Situ bisphenol A 4.3517123778
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 4.2616152834
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 4.8912023789 16685392
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 4.8918414057
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.2319014326
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 3.2016201981
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.5612490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 6.2620419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 6.2617066447 18337622 6189445
MESH:D002294 Carcinoma, Squamous Cell Curcumin 6.2618462866
MESH:D006332 Cardiomegaly Norepinephrine 5.9011179087
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.9018670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Genistein 6.2416332659
MESH:D002318 Cardiovascular Diseases Isoflavones 6.2417689850
MESH:D002375 Catalepsy Norepinephrine 4.918216760
MESH:D002386 Cataract Acetaminophen 2.1810977129
MESH:D002389 Catatonia olanzapine 5.6018071103 16772815
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 8.5112371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 8.517505956 17174075 21159647 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 8.5118566989
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.634080065
MESH:D002659 Child Development Disorders, Pervasive Serotonin 5.5221254450
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 5.5220734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.5319052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.5316835633
MESH:D002779 Cholestasis Cyclosporine 6.1519486331
MESH:D002779 Cholestasis pirinixic acid 6.1519176532
MESH:D021081 Chronobiology Disorders Serotonin 6.0417157402
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.8015340226 16354765 8697196 12621046 15668235
MESH:D003092 Colitis Curcumin 7.9116804969 16782535 18200517
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 7.9118200517 17991707 11698051 18023891 16804969 17936198 16867261 16782535 16474422
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 3.1917276891
MESH:D003103 Coloboma Curcumin 3.9818809619
MESH:D003110 Colonic Neoplasms Curcumin 4.9819359593 16340194
MESH:D003110 Colonic Neoplasms Dexamethasone 4.9815824018
MESH:D003110 Colonic Neoplasms Genistein 4.9817182828
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.1720501625
MESH:D015179 Colorectal Neoplasms Cisplatin 3.1715273666
MESH:D015179 Colorectal Neoplasms Isoflavones 3.1717116718
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.5214669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 4.2818497527
MESH:D023903 Coronary Restenosis arsenic trioxide 3.5812609071
MESH:D003371 Cough Capsaicin 4.5310350223
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 8.1310525206
MESH:D019465 Craniofacial Abnormalities Carbamazepine 8.139014606
MESH:D019465 Craniofacial Abnormalities Dexamethasone 8.1317728286
MESH:D019465 Craniofacial Abnormalities Reactive Oxygen Species 8.1315736158
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 8.1320055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Valproic Acid 8.1317688650 16575769 8888407
MESH:D003456 Cryptorchidism Diethylstilbestrol 3.9516002989 12952375
MESH:D003556 Cystitis Cyclophosphamide 4.3418433785 18295254 12913760 12161096 18093676 18710439 10498854 16651033 16614059 15643279 16413132 17010015 12388444 11948286 15276878 18483878 16989017 17979934 18372110 10700343
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.5115213294
MESH:D003866 Depressive Disorder Sertraline 4.3015014590 18822694 20305041
MESH:D003865 Depressive Disorder, Major Sertraline 4.8216968574
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 5.3812438553
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 5.3811298694 16780908 16823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.0918249437
MESH:D002658 Developmental Disabilities olanzapine 4.2417069543
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 3.5511751995 10990075 15331540
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 2.9918772604
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 8.5418403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 8.5420387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 8.5416647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 8.5417107852
MESH:D003928 Diabetic Nephropathies Curcumin 7.2518204486
MESH:D003928 Diabetic Nephropathies Estradiol 7.2519279558
MESH:D003929 Diabetic Neuropathies Progesterone 3.8717187935
MESH:D003967 Diarrhea Dexamethasone 6.667237001
MESH:D003967 Diarrhea Serotonin 6.6611488427 8112388 10446763
MESH:D004244 Dizziness Astemizole 5.823105558
OMIM:607208 DRAVET SYNDROME Carbamazepine 4.8311748493
MESH:D004342 Drug Hypersensitivity Carbamazepine 3.9916538176 20216337 15057820 16538175
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.4718071297 10663392 17906064 12153990 16227642 2444490 11834606 12392966 18713872 19923254 14725611 11421492 16177239 16485898 16081117 16393943 12705907 19164858 15968718 19420014 19085960 14550746 16109766 15619225 11287661 12540782 19739265 10774834 14986274 19370779 10915739 17562736 16781746 12594235 11461765 17522070 19416960 11529661 11739529 12958197 11743745
MESH:D056486 Drug-Induced Liver Injury Carbamazepine 9.4717465707
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 9.4719107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 9.4720420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 9.471733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.4519426721
MESH:D004362 Drug Toxicity Carbamazepine 11.0720216337
MESH:D004362 Drug Toxicity Cisplatin 11.0715033597 12649298 12231392 19839026
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 11.0711462148
MESH:D004381 Duodenal Ulcer Capsaicin 7.6310671773 11535926
MESH:D004381 Duodenal Ulcer Curcumin 7.6317351913
MESH:D004417 Dyspnea cypermethrin 4.7516487989
MESH:D004421 Dystonia Phenobarbital 8.491851702
MESH:D004421 Dystonia Valproic Acid 8.491851702
MESH:D004485 Eczema Dexamethasone 3.8612438553
MESH:D004487 Edema Dexamethasone 11.9019703484
MESH:D004487 Edema pirinixic acid 11.9012083418
MESH:D004487 Edema Serotonin 11.9018841975
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.9012711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.2615322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Carbamazepine 7.6117654737
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 7.6117692515
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 9.7916402032
MESH:D004714 Endometrial Hyperplasia Genistein 9.7916402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 9.9615700306 16804899
MESH:D016889 Endometrial Neoplasms Estradiol 9.9619148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Genistein 9.9611473722
MESH:D004715 Endometriosis Mifepristone 12.1316134523
MESH:D004715 Endometriosis Progesterone 12.1316134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 12.139294722 10568697
MESH:D004802 Eosinophilia Astemizole 7.471355641
MESH:D004802 Eosinophilia Cyclophosphamide 7.4711006010
MESH:D004816 Epidermal Necrolysis, Toxic Carbamazepine 4.6516538176 20485159 19915237 16415921 18855540
MESH:D004831 Epilepsies, Myoclonic Carbamazepine 14.9017275665
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 14.903659116
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 14.9017275665 3659116
MESH:D004828 Epilepsies, Partial Carbamazepine 13.2515008574 16628512 17116037
MESH:D004828 Epilepsies, Partial Phenobarbital 13.2511558140 3922381
MESH:D004828 Epilepsies, Partial Valproic Acid 13.2516628512 3922381
MESH:D004827 Epilepsy Carbamazepine 16.8818234410 20417680 17178248 17465707 7988514 19620853 821787 19439326 19700373 9014606
MESH:D004827 Epilepsy Epinephrine 16.88821787
MESH:D004827 Epilepsy Norepinephrine 16.88821787
MESH:D004827 Epilepsy Phenobarbital 16.8820417680
MESH:D004827 Epilepsy Valproic Acid 16.8820417680 18234410
MESH:D004832 Epilepsy, Absence Phenobarbital 7.076401628
MESH:D004832 Epilepsy, Absence Valproic Acid 7.077562514 6254150 6426943
MESH:D017029 Epilepsy, Complex Partial Carbamazepine 15.857750514
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 15.857750514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 15.857750514
MESH:D004830 Epilepsy, Tonic-Clonic Carbamazepine 14.2315276670 3659116
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 14.233659116
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 14.233659116
MESH:D004916 Erythromelalgia Carbamazepine 5.0919549232
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.4716302075
MESH:D004935 Esophageal Diseases Capsaicin 5.0719566590
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.0612903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 6.0616530937
MESH:D004938 Esophageal Neoplasms Cisplatin 6.0615173087 16785472 15464296 17638652 16481741
MESH:D005076 Exanthema Carbamazepine 4.8320485159
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.5211564622
MESH:D005234 Fatty Liver arsenic trioxide 23.3915073043
MESH:D005234 Fatty Liver Curcumin 23.3919297423
MESH:D005234 Fatty Liver Cyclosporine 23.3919224547
MESH:D005234 Fatty Liver Diethylnitrosamine 23.3920387270 21071580
MESH:D005234 Fatty Liver pirinixic acid 23.3919236843 20131406
MESH:D005234 Fatty Liver Valproic Acid 23.3919224547 14986274
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.2415751030 16513791 16534752 16002989 16611131
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.8411858732
MESH:D005315 Fetal Diseases Valproic Acid 4.2416575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.538888407 18558336
MESH:D005355 Fibrosis Curcumin 16.1618705752
MESH:D005355 Fibrosis Cyclosporine 16.1612168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 16.1620067830
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 16.1617994277
MESH:D005499 Folliculitis Astemizole 5.271671328
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.6616904648
MESH:D005756 Gastritis Acetaminophen 3.0316983495
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.0818462866
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.3116452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.588708960
MESH:D005909 Glioblastoma Capsaicin 9.5518405923
MESH:D005909 Glioblastoma Curcumin 9.5517596214
MESH:D005909 Glioblastoma Genistein 9.5516598420
MESH:D018316 Gliosarcoma Cyclophosphamide 4.8811389073
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.9510696789
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.4216376943 11014644 15172196
MESH:D006258 Head and Neck Neoplasms Cisplatin 6.5915102660 15464296
MESH:D006258 Head and Neck Neoplasms Curcumin 6.5918829502 18462866
MESH:D034381 Hearing Loss Cisplatin 3.7619898482
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.8915464296
MESH:D006356 Heartburn Capsaicin 5.0719566590
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 5.2120471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.2111294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.1220558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.7915720958
MESH:D006467 Hemophilia A Cyclophosphamide 4.6711918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.7711000095
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 4.8914986274
MESH:D006505 Hepatitis cypermethrin 4.5716487989
MESH:D006529 Hepatomegaly fenvalerate 15.7015602828
MESH:D006529 Hepatomegaly Phenobarbital 15.7016109766
MESH:D006529 Hepatomegaly pirinixic acid 15.7019772884 16221962 18467677 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 15.7015340226 12621046 16120746
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.4217701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.817520565
MESH:D006558 Herpes Genitalis Estradiol 4.3815709030
MESH:D006689 Hodgkin Disease Cisplatin 9.6316170182 16200630
MESH:D006689 Hodgkin Disease Cyclophosphamide 9.6317606976 16135485
MESH:D006689 Hodgkin Disease Procarbazine 9.6317606976 16135485
MESH:D019584 Hot Flashes Estradiol 8.2817088409
MESH:D019584 Hot Flashes Isoflavones 8.2814716179 17290160
MESH:D006816 Huntington Disease Sertraline 5.4018403212
MESH:D006849 Hydrocephalus Valproic Acid 4.2317688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.408697196 16354765 15340226 18606429 16959395
MESH:D006930 Hyperalgesia Acetaminophen 6.3516870215
MESH:D006930 Hyperalgesia Capsaicin 6.3517434803 17043245
MESH:D006937 Hypercholesterolemia Curcumin 3.4918704882
MESH:D006943 Hyperglycemia pirinixic acid 2.6320558911
MESH:D020138 Hyperhomocysteinemia Carbamazepine 4.1910459572
MESH:D006948 Hyperkinesis Methamphetamine 4.8817658665
MESH:D006963 Hyperphagia olanzapine 5.6017933447
MESH:D006965 Hyperplasia Carbamazepine 9.2518773962
MESH:D006965 Hyperplasia Diethylstilbestrol 9.2512960047 14722030
MESH:D006973 Hypertension Cyclosporine 6.9110903974
MESH:D006973 Hypertension Dexamethasone 6.9117042910
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 6.9118850075 18670907
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.0116612254
MESH:D007021 Hypospadias Diethylstilbestrol 3.9616002989
MESH:D007022 Hypotension Dopamine 12.346740701
MESH:D007022 Hypotension Epinephrine 12.346740701
MESH:D007022 Hypotension Norepinephrine 12.346740701
MESH:D007154 Immune System Diseases Cyclophosphamide 4.6916076520
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.7815869954
MESH:D007246 Infertility Diethylstilbestrol 3.7515036965
MESH:D007248 Infertility, Male Atrazine 5.8512948887
MESH:D007248 Infertility, Male Cyclophosphamide 5.857193160 16517039
MESH:D007249 Inflammation Capsaicin 15.1916956363
MESH:D007249 Inflammation Curcumin 15.1918403477 17151092 16956363
MESH:D007249 Inflammation Dexamethasone 15.198960868 11099482
MESH:D007249 Inflammation Diethylnitrosamine 15.1918785209
MESH:D007249 Inflammation Progesterone 15.1915869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 15.1912878042 12200463
MESH:D015212 Inflammatory Bowel Diseases Curcumin 5.6918596194 18200517
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 5.6918200517
MESH:D007299 Insect Bites and Stings cypermethrin 5.3315189238
MESH:D007333 Insulin Resistance bisphenol A 9.7616393666
MESH:D007333 Insulin Resistance Estradiol 9.7616393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 9.7616306350
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 3.9917994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.6710783313
MESH:D002532 Intracranial Aneurysm Reactive Oxygen Species 4.4319381132
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.7716580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.7915604871
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.4915464296
MESH:D007674 Kidney Diseases Acetaminophen 11.1512587719 15629191
MESH:D007674 Kidney Diseases Cisplatin 11.1519839026 15190930 12649298 18289764 12231392
MESH:D007674 Kidney Diseases Cyclosporine 11.1518776723 10903974 8314463
MESH:D007674 Kidney Diseases Estradiol 11.1515618244
MESH:D007680 Kidney Neoplasms Cyclosporine 9.4212371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 9.4215003126 16762066 14681315
MESH:D007680 Kidney Neoplasms Estradiol 9.4215610895
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.1511231351
MESH:D007859 Learning Disorders Diethylstilbestrol 3.4517184923
MESH:D007889 Leiomyoma Curcumin 3.9818555241
MESH:D007938 Leukemia arsenic trioxide 12.0815070760
MESH:D007938 Leukemia Curcumin 12.0818462866
MESH:D007938 Leukemia Cyclophosphamide 12.0810602166
MESH:D007938 Leukemia Genistein 12.0818980019 17468513
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.1918587576 17802794 17658394 17296974 17008537 18172266
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 7.8712560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 7.8716106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.6716972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 7.0014633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 7.0010373061
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.1919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.3917050201 16467208 16968895 19850784 20471514
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 3.3917596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 2.7817649720 15748426 16823087 17107899 19035177 11161223 9834237 15336539 19075265 16966277 16112521 12018890 15213294 16331271 16891316 19225113 11468182 17869043 12712474 16330433 17712046 15622746 19642359 17217047 12679006
MESH:D015458 Leukemia, T-Cell arsenic trioxide 9.7116882451
MESH:D015458 Leukemia, T-Cell Curcumin 9.7116106398
MESH:D007970 Leukopenia Cyclophosphamide 4.3310052129 11830472
MESH:D017513 Lichen Nitidus Astemizole 5.822563723
MESH:D008064 Lipidoses Sertraline 4.3517567588
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 5.3618522880 19638242 20032147 18407596 18665156
MESH:D008103 Liver Cirrhosis Phenobarbital 5.3621047994
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 7.2718705752 18006644 17355460
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 7.2716718785
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 7.2714716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 7.2717823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 7.2715474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 7.2712878042
MESH:D008107 Liver Diseases Acetaminophen 13.0619784758 12587719 19460945 11587558 12969438 16611625 19014921 16610002
MESH:D008107 Liver Diseases Capsaicin 13.0616956363
MESH:D008107 Liver Diseases Curcumin 13.0616956363
MESH:D008107 Liver Diseases cypermethrin 13.0615991261
MESH:D008107 Liver Diseases Diethylnitrosamine 13.0617034775
MESH:D008107 Liver Diseases Phenobarbital 13.0619363144
MESH:D017114 Liver Failure, Acute Acetaminophen 2.6816871587 17185352
MESH:D008113 Liver Neoplasms arsenic trioxide 17.4514682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 17.4520195826 21137059
MESH:D008113 Liver Neoplasms Diethylnitrosamine 17.4512112319 19996281 20452335 19255062 20101389 19256749 19499222 18978307 12771043 20583210 19812893 15885732 19254457 20118626 18648771 2422723 18644402 19090486 19426721 19427195 18977376 19850985 20137499 19551842 19294768 21047994 18754104 19073162 15175105 20434301 19690152 2862719 19638242 19642983 21278145 20501860 9163691 16942905 20405173 21167192 10737359 21071580 20492335 19833225
MESH:D008113 Liver Neoplasms Diethylstilbestrol 17.4516712894 15890375
MESH:D008113 Liver Neoplasms Phenobarbital 17.4519073162 19812893 15975961 19482888 8742319 21047994
MESH:D008113 Liver Neoplasms pirinixic acid 17.4520007298 15890375 16377806
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.4516984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 14.1720377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 14.1719519916 16267830 21159647 19539802 17854601 18079962 18282651 18253720 19004024 18775883 17174075 19009564 18093689 18164116 3124819 18544905 16842330 17942915 19126423 9362446 2563599 18308698
MESH:D008114 Liver Neoplasms, Experimental kojic acid 14.1718544905
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 14.1717172636 2563599 1399818 18308698 6150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 14.1712151625
MESH:D008133 Long QT Syndrome arsenic trioxide 11.0215213294
MESH:D008133 Long QT Syndrome Astemizole 11.0218472280 11989578
MESH:D008133 Long QT Syndrome olanzapine 11.0220210726
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 3.6217228818
MESH:D008175 Lung Neoplasms arsenic trioxide 8.9611798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 8.9618520028 20464547 17053015 18816296 6695378 18569708 20869020 20135361 20064080
MESH:D008175 Lung Neoplasms Cisplatin 8.9617225452 11798837 6189445
MESH:D008175 Lung Neoplasms Curcumin 8.9619359593 18462866 16243823
MESH:D008175 Lung Neoplasms Dexamethasone 8.9615824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 8.9620512841 20970405 21163286 6695378
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.9611884234 19555203
MESH:D008180 Lupus Erythematosus, Systemic Carbamazepine 3.3516628512
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.5215166399
MESH:D008223 Lymphoma Curcumin 9.9818462866
MESH:D008223 Lymphoma Cyclophosphamide 9.9812854902
MESH:D008223 Lymphoma Diethylstilbestrol 9.9815700306
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 4.0116675587
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 3.6511911406
MESH:D016399 Lymphoma, T-Cell Curcumin 4.0816173963
MESH:D008288 Malaria Astemizole 4.2916816845
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.8716002989
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 10.8511408345 11807958 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Genistein 10.8514578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Procarbazine 10.8511921183
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 10.8511408345 17203775
MESH:D020149 Manganese Poisoning Estradiol 3.8419453300
MESH:D008545 Melanoma Cisplatin 4.5118176117 16432458 12883367 16248763 12374674 17023156 12393984 17761969 11135225 15577323 18332650 16809738 18505091
MESH:D008545 Melanoma Curcumin 4.5118462866 17885582
MESH:D008545 Melanoma Reactive Oxygen Species 4.5117992120
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.1415990972
MESH:D008546 Melanoma, Experimental Acetaminophen 8.7819513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 8.7816388313
MESH:D008569 Memory Disorders Curcumin 3.5617263510
MESH:D001523 Mental Disorders Moclobemide 10.2316856516
MESH:D001523 Mental Disorders olanzapine 10.2316856516
MESH:D001523 Mental Disorders Sertraline 10.2316856516
MESH:D008607 Mental Retardation Carbamazepine 3.479014606
MESH:D008654 Mesothelioma Atrazine 5.631916698
MESH:D008654 Mesothelioma Cisplatin 5.6317638057
MESH:D008659 Metabolic Diseases olanzapine 4.8219142110
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.1416801185
MESH:D008881 Migraine Disorders Tyramine 6.7710792367
MESH:D008881 Migraine Disorders Valproic Acid 6.7718765137 18803445
OMIM:309850 MONOAMINE OXIDASE A marker/mechanism
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.6916381670
MESH:D009101 Multiple Myeloma arsenic trioxide 13.4815949261 14977855 19417148 19549372 11468182
MESH:D009101 Multiple Myeloma Capsaicin 13.4817505005
MESH:D009101 Multiple Myeloma Curcumin 13.4819372569
MESH:D009101 Multiple Myeloma Dexamethasone 13.4816118317 15867202 15744524
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.2817962980
MESH:D009135 Muscular Diseases marker/mechanism 15946989
MESH:D009135 Muscular Diseases pirinixic acid 2.8916239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.468888407
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.0318349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 10.0716105982 16882451
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 10.079809623
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 10.0717596541
MESH:D009203 Myocardial Infarction Genistein 4.6517141266
MESH:D009203 Myocardial Infarction pirinixic acid 4.6519151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.5112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 16.2616810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 16.2617141266
MESH:D015428 Myocardial Reperfusion Injury Norepinephrine 16.2615642760
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 16.2616411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.8417484760
MESH:D009224 Myotonia Congenita Carbamazepine 4.8320399394
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 8.3316624393
MESH:D009361 Neoplasm Invasiveness Curcumin 8.3318495463
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.289029167 3581430
MESH:D009369 Neoplasms Benzo(a)pyrene 15.2011141357
MESH:D009369 Neoplasms Cisplatin 15.2016773208
MESH:D009369 Neoplasms Cyclophosphamide 15.2018854779
MESH:D009369 Neoplasms Diethylstilbestrol 15.2015313581
MESH:D009369 Neoplasms fenvalerate 15.202895627
MESH:D009369 Neoplasms pirinixic acid 15.2017405874
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 3.8912497104
MESH:D009389 Neovascularization, Pathologic Estradiol 3.1017289903
MESH:D009395 Nephritis, Interstitial Cisplatin 3.8515464296
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.7917954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.7519348381 18481113
MESH:D009421 Nervous System Malformations bisphenol A 30.5216427766 11399458
MESH:D009421 Nervous System Malformations Carbamazepine 30.5216990009
MESH:D009421 Nervous System Malformations Diethylstilbestrol 30.5211399458
MESH:D009421 Nervous System Malformations Estradiol 30.5216427766 11399458
MESH:D009421 Nervous System Malformations Genistein 30.5216427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 30.5214600291
MESH:D009423 Nervous System Neoplasms Curcumin 4.9818462866
MESH:D009436 Neural Tube Defects arsenic trioxide 5.8710525206
MESH:D009436 Neural Tube Defects Valproic Acid 5.8716359493 8888407
MESH:D009447 Neuroblastoma Cisplatin 6.068761367
MESH:D009447 Neuroblastoma Cyclophosphamide 6.0616115947 8761367 15176712
MESH:D019636 Neurodegenerative Diseases Acetaminophen 6.4418514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 6.4420387270
MESH:D017599 Neuroectodermal Tumors Cisplatin 9.428761367
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 9.428761367 12837982
MESH:D020078 Neurogenic Inflammation Capsaicin 4.5017961222
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.4720387270
MESH:D020258 Neurotoxicity Syndromes Methyl Parathion 4.3919784758
MESH:D009503 Neutropenia Cyclophosphamide 3.748291058
MESH:D009669 Nose Neoplasms Procarbazine 5.439385384
MESH:D009759 Nystagmus, Pathologic Astemizole 5.826135121
MESH:D009765 Obesity Capsaicin 9.0419056576
MESH:D009765 Obesity Curcumin 9.0419297423
MESH:D009765 Obesity olanzapine 9.0418515891
MESH:D009765 Obesity pirinixic acid 9.0420558911
MESH:D009845 Oligospermia Cyclophosphamide 4.0816517039
MESH:D010018 Osteomalacia Carbamazepine 9.9917016548
MESH:D010018 Osteomalacia Phenobarbital 9.9917016548
MESH:D010024 Osteoporosis Curcumin 9.6218719352
MESH:D010024 Osteoporosis Genistein 9.6219401787
MESH:D010024 Osteoporosis Isoflavones 9.6216562857
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.5016169203
MESH:D010049 Ovarian Diseases bisphenol A 4.3511985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 19.0919769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Cisplatin 19.0919769630 15464296 6897625 17225452
MESH:D010051 Ovarian Neoplasms Curcumin 19.0918462866 19020741
MESH:D010051 Ovarian Neoplasms Estradiol 19.0919401270
MESH:D010051 Ovarian Neoplasms Genistein 19.0919005980
MESH:D010051 Ovarian Neoplasms Mifepristone 19.0916525653
MESH:D010051 Ovarian Neoplasms Progesterone 19.0917393432 16525653
MESH:D010146 Pain Acetaminophen 11.9816870215
MESH:D010146 Pain Capsaicin 11.9817084039 19081190 16996476 18987195 17043245 17434803
MESH:D010146 Pain Carbamazepine 11.9815215642
MESH:D010146 Pain Cyclophosphamide 11.9818093676 12161096
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 20.6215580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 20.6219003803
MESH:D010190 Pancreatic Neoplasms Curcumin 20.6217440100 19196508 19401701
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 20.6211332152
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 20.6216540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 20.6216965848
MESH:D010190 Pancreatic Neoplasms Reactive Oxygen Species 20.6215580305
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 3.6317698068
MESH:D010235 Paraganglioma arsenic trioxide 3.5719927285
MESH:D010243 Paralysis fenvalerate 5.378952708
MESH:D010267 Parapsoriasis Carbamazepine 5.0816538176
MESH:D010300 Parkinson Disease 3-methoxymethyl-7-(4,4,4-trifluorobutoxy)-3,3a,4,5-tetrahydro-1,3-oxazolo(3,4-a)quinolin-1-one 5.6915178694
MESH:D010300 Parkinson Disease Atrazine 5.6917218051
OMIM:167400 PAROXYSMAL EXTREME PAIN DISORDER Carbamazepine 5.2917145499 17679678
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.6012520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.7115464296
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.5214722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.0515687265 16977796
MESH:D010997 Pleural Neoplasms Cisplatin 4.7017638057
MESH:D011041 Poisoning Methyl Parathion 4.4617603234
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.9618163543
MESH:D011230 Precancerous Conditions Cyclosporine 12.1512371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 12.152563599
MESH:D011230 Precancerous Conditions Phenobarbital 12.152563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 6.5121297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 6.5121297632
MESH:D011248 Pregnancy Complications Carbamazepine 4.549014606
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 23.8110548101
MESH:D011297 Prenatal Exposure Delayed Effects Carbamazepine 23.819014606
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 23.8117184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 23.8111222880 11896295 11399792 11118676
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 23.8120603192
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 8.6520887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 8.6520887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.1319131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.1317292933
MESH:D011471 Prostatic Neoplasms bisphenol A 3.1316740699
MESH:D011471 Prostatic Neoplasms Clorgyline 3.1319691856
MESH:D011471 Prostatic Neoplasms Curcumin 3.1311398177 10851300 18156803 18226269 12497104 15129424 18769126
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 3.1317136230
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 3.1315046698 17136230 15846301
MESH:D011471 Prostatic Neoplasms Estradiol 3.1316740699
MESH:D011471 Prostatic Neoplasms Genistein 3.1316925846 15378649 15256057
MESH:D011471 Prostatic Neoplasms Isoflavones 3.1317374662 17571952 17219775 16365062
MESH:D019310 Pseudolymphoma Carbamazepine 17.4412752131 9591791
MESH:D019310 Pseudolymphoma Phenobarbital 17.4412752131
MESH:D019310 Pseudolymphoma Valproic Acid 17.4412752131 11422049
MESH:D011565 Psoriasis Cyclosporine 1.9716882103
MESH:D011595 Psychomotor Agitation olanzapine 4.9618685284
MESH:D011629 Puberty, Precocious bisphenol A 4.1510548101
MESH:D011656 Pulmonary Emphysema Curcumin 3.9719168576
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 3.0116636934
MESH:D051437 Renal Insufficiency Cisplatin 3.7915464296
MESH:D015427 Reperfusion Injury Capsaicin 5.6518460982 19211983
MESH:D015427 Reperfusion Injury pirinixic acid 5.6519058328
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 7.3718379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 7.3718379247 11700416
MESH:D012135 Respiratory Sounds Atrazine 3.9011874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2318990726
MESH:D012208 Rhabdomyosarcoma Valproic Acid 3.5919155313
MESH:D012221 Rhinitis, Allergic, Perennial Astemizole 4.7810822083
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.5918045962
MESH:D012509 Sarcoma Curcumin 3.5618462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 8.3516646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 8.3514601052
MESH:D012559 Schizophrenia olanzapine 3.6520107430 17726453 20521326
MESH:D012559 Schizophrenia Valproic Acid 3.6519110320 15737665
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 4.2316636934
MESH:D012640 Seizures Carbamazepine 7.409844417 19414003 16876388 16180713 15946322 16938433 9046859
MESH:D012640 Seizures Phenobarbital 7.404039156 16876388 3137016 11442880
MESH:D012640 Seizures Valproic Acid 7.401511512 16876388 11044598 15475178 3137016 11738929 14763951 17978042
MESH:D003294 Seizures, Febrile Phenobarbital 4.196407741
MESH:D018805 Sepsis Curcumin 3.5518389075
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 4.3510029692 19755658
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 4.3516192470
MESH:D012893 Sleep Disorders Carbamazepine 4.4919414003
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.7015464296
MESH:D013088 Spermatocele Diethylstilbestrol 4.0716002989 16709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 4.8816517039
MESH:D013119 Spinal Cord Injuries Progesterone 3.6516503802 15862959
MESH:D016135 Spinal Dysraphism Valproic Acid 3.2819490988
MESH:D013226 Status Epilepticus Valproic Acid 3.9012833885
MESH:D013262 Stevens-Johnson Syndrome Carbamazepine 4.5919915237 16415921 19694795 15057820 16538176 20485159 18855540
MESH:D013272 Stomach Diseases Dexamethasone 3.6915472012
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.0017007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 4.0020155912 2093021
MESH:D013274 Stomach Neoplasms Cisplatin 4.0015958060 18396642 17522103
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 4.0018456281
MESH:D013276 Stomach Ulcer Curcumin 5.6919188055 16631530
MESH:D013276 Stomach Ulcer Dexamethasone 5.6915138204
MESH:D019966 Substance-Related Disorders bisphenol A 3.3616684133 16045194
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 4.4212837982
MESH:D013610 Tachycardia Norepinephrine 4.833261545
MESH:D017180 Tachycardia, Ventricular olanzapine 4.7320210726
MESH:D013705 Temporomandibular Joint Disorders Capsaicin 5.0817997062
MESH:D013736 Testicular Neoplasms Cisplatin 4.0415464296 17225452
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.2612697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 9.1319014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 9.137505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 9.131399818
MESH:D013978 Tibial Fractures Estradiol 4.0419048282
MESH:D016171 Torsades de Pointes arsenic trioxide 8.5415213294
MESH:D016171 Torsades de Pointes Astemizole 8.548256756 9583453
MESH:D014178 Translocation, Genetic Valproic Acid 4.5917262798
MESH:D014202 Tremor fenvalerate 4.928952708
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 3.893119515
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 16.0312973940 11780464 12845720 20435036
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 16.0317053015
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 16.0315464296 12973940 17225452
MESH:D001749 Urinary Bladder Neoplasms Curcumin 16.0318593936
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 16.0314692829
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 16.0316712894 16452187 17306315
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.028888407
MESH:D014565 Urogenital Neoplasms Curcumin 4.6318462866
MESH:D014570 Urologic Diseases cypermethrin 5.2216487989
MESH:D014581 Urticaria Acetaminophen 7.1010982225
MESH:D014581 Urticaria Astemizole 7.102883202 1976298 3097109 3080510 3134034 2565098 2568013 2568189 2885854 1683191 2859714 2147912
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 7.8616803524
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 7.8616175088
MESH:D014591 Uterine Diseases bisphenol A 11.6714652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 11.6714652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 3.4715809267 16690809
MESH:D014605 Uveitis Cyclosporine 9.621336536
MESH:D014605 Uveitis Dexamethasone 9.621336536
MESH:D014625 Vaginal Neoplasms Cisplatin 9.0315577323
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 9.0316002989 16513791
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.9512125929
MESH:D014717 Vertigo Astemizole 5.823105558
MESH:D014839 Vomiting Cisplatin 4.0711897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.6015886252
MESH:D015430 Weight Gain olanzapine 4.6219434072 17933447 20107430
MESH:D014985 Xerophthalmia Cyclosporine 3.7917120751
Pathway ID Pathway Name
KEGG:00330 Arginine and proline metabolism
REACT:13433 Biological oxidations
KEGG:00982 Drug metabolism - cytochrome P450
KEGG:00260 Glycine, serine and threonine metabolism
KEGG:00340 Histidine metabolism
KEGG:01100 Metabolic pathways
KEGG:00360 Phenylalanine metabolism
REACT:13685 Synaptic Transmission
KEGG:00380 Tryptophan metabolism
KEGG:00350 Tyrosine metabolism
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA236
    • No data
    Releated disease ID Related disease Name
    PA447321Depressive Disorder, Major
    PA447207Depressive Disorder
    PA445876Tobacco Use Disorder
    PA445876Tobacco Use Disorder
    PA447216Schizophrenia
    PA447278Depression
    PA447199Bipolar Disorder
    PA443959Dyskinesia, Drug-Induced
    PA443970Dystonia
    PA446736Hypokinesia
    PA444993Muscle Rigidity
    PA445917Tremor
    Releated drug ID Related drug Name
    PA164713257Selective serotonin reuptake inhibitors
    PA452229antidepressants
    PA449015citalopram
    PA449690fluvoxamine
    PA450801paroxetine
    PA451333sertraline
    PA450626nicotine
    PA164712904Monoamine oxidase A inhibitors
    PA449396dopamine
    PA450649norepinephrine
    PA451898vitamin c
    PA452233antipsychotics
    PA449673fluoxetine
    PA449396dopamine
    PA451257risperidone
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00191 antagonist Fen-phen Adrenergic Agents;Central Nervous System Stimulants;Sympathomimetics;Central Nervous System Agents;Appetite Depressants;Anorexigenic Agents;Stimulants
    DB00752 antagonist Tranylcypromine Antidepressants;Anti-anxiety Agents;Antidepressive Agents;Monoamine Oxidase Inhibitors
    DB00780 antagonist Phenelzine Antidepressants;Antidepressive Agents;Monoamine Oxidase Inhibitors
    DB00805 antagonist Minaprine Central Nervous System Agents;Antiparkinson Agents;Antidepressive Agents
    DB00909 antagonist Zonisamide Antioxidants;Anticonvulsants
    DB01037 inhibitor Selegiline Central Nervous System Agents;Antiparkinson Agents;Antidyskinetics;Neuroprotective Agents;Monoamine Oxidase Inhibitors;Dopaminergics
    DB01171 inhibitor Moclobemide Antidepressive Agents;Monoamine Oxidase Inhibitors
    DB01247 antagonist Isocarboxazid Antidepressants;Antidepressive Agents;Monoamine Oxidase Inhibitors
    DB01363 antagonist Tartephedreel
    DB01442 antagonist MMDA Psychotropic Drugs
    DB01472 antagonist 4-Methoxyamphetamine Hallucinogens
    DB01577 antagonist Methamphetamine Adrenergic Agents;Dopamine Agents;Dopamine Uptake Inhibitors;Adrenergic Uptake Inhibitors;Central Nervous System Stimulants;Sympathomimetics
    DB01626 antagonist Pargyline Antihypertensive Agents;Monoamine Oxidase Inhibitors
    DB03147 - Flavin-Adenine Dinucleotide
    DB04017 - N-Methyl-N-Propargyl-3-(2,4-Dichlorophenoxy)Propylamine Antidepressive Agents;Monoamine Oxidase Inhibitors
    DB07641 - DECYL(DIMETHYL)PHOSPHINE OXIDE
    DB07919 - 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE
    Drugbank ID Action Drug Name Description
    DB00140 - Riboflavin Vitamins (Vitamin B Complex);Radiation-Sensitizing Agents;Photosensitizing Agents;Vitamin B Complex
    DB00184 - Nicotine Anti-craving Agents;Central Nervous System Agents;Autonomic drugs;Nicotinic Agonists;Ganglionic Stimulants
    DB00186 - Lorazepam Anti-anxiety Agents;Hypnotics and Sedatives;Antiemetics;Anticonvulsants;Benzodiazepines;GABA Modulators
    DB00191 - Fen-phen Adrenergic Agents;Central Nervous System Stimulants;Sympathomimetics;Central Nervous System Agents;Appetite Depressants;Anorexigenic Agents;Stimulants
    DB00315 - Zolmitriptan Vasoconstrictor Agents;Anti-inflammatory Agents;Anti-migraine Agents;Selective Serotonin Agonists;Serotonin Agonists
    DB00368 - Norepinephrine Vasoconstrictor Agents;Sympathomimetics;Adrenergic alpha-Agonists
    DB00388 - Vasosulf Oph Soln Vasoconstrictor Agents;Sympathomimetics;Adrenergic alpha-Agonists;Mydriatics;Cardiotonic Agents;Nasal Decongestants
    DB00397 - Tussaminic DH Pediatric Syrup Sympathomimetics;Appetite Depressants;Adrenergic alpha-Agonists;Nasal Decongestants
    DB00601 - Linezolid Anti-Infective Agents;Protein Synthesis Inhibitors;Antibacterial Agents
    DB00624 - Uni-Bol Androgens
    DB00669 - Sumatriptan Vasoconstrictor Agents;Selective Serotonin Agonists;Serotonin Agonists
    DB00780 substrate Phenelzine Antidepressants;Antidepressive Agents;Monoamine Oxidase Inhibitors
    DB00852 - Tussin Cough Medicine DM Antitussive Expectorant Decongestant Vasoconstrictor Agents;Adrenergic Agents;Sympathomimetics;Central Nervous System Agents;Bronchodilator Agents;Nasal Decongestants
    DB00918 - Almotriptan Vasoconstrictor Agents;Anti-inflammatory Agents;Anti-migraine Agents;Selective Serotonin Agonists;Serotonin Agonists
    DB00953 - Rizatriptan Vasoconstrictor Agents;Anti-inflammatory Agents;Anti-migraine Agents;Selective Serotonin Agonists;Serotonin Agonists
    DB00988 - Dopamine Dopamine Agents;Sympathomimetics;Cardiotonic Agents;Sympathomimetic
    DB01068 - Clonazepam Anticonvulsants;Benzodiazepines;GABA Modulators
    DB01104 substrate Sertraline Antidepressants;Selective Serotonin Reuptake Inhibitors (SSRIs);Antidepressive Agents;Serotonin Uptake Inhibitors
    DB01171 inhibitor Moclobemide Antidepressive Agents;Monoamine Oxidase Inhibitors
    DB01235 - Sinemet CR Dopamine Agents;Antiparkinson Agents;Antidyskinetics
    DB01445 - Bufotenine Serotonin Antagonists;Hallucinogens
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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