AutismKB 2.0

Annotation Detail for MATN1


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Basic Information Top
Gene Symbol:MATN1 ( CMP,CRTM )
Gene Full Name: matrilin 1, cartilage matrix protein
Band: 1p35.2
Quick LinksEntrez ID:4146; OMIM: 115437; Uniprot ID:MATN1_HUMAN; ENSEMBL ID: ENSG00000162510; HGNC ID: 6907
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
Scoliosis
radiographically evident osteoarthritis
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001149 Arsenates [Atrazine co-treated with Arsenates] results in increased expression of MATN1 mRNAaffects cotreatment|increases expression 18585445
C006632 arsenic trioxide arsenic trioxide results in increased expression of MATN1 mRNAincreases expression 20458559
D001280 Atrazine [Atrazine co-treated with Arsenates] results in increased expression of MATN1 mRNAaffects cotreatment|increases expression 18585445
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of MATN1 mRNAdecreases expression 20440473
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of MATN1 mRNAincreases expression 20440473
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of MATN1 mRNAincreases expression 18255322
C091888 monoisoamyl-2,3-dimercaptosuccinate [sodium arsenite co-treated with monoisoamyl-2,3-dimercaptosuccinate] results in decreased expression of MATN1 mRNAaffects cotreatment|decreases expression 19615344
C017947 sodium arsenite [sodium arsenite co-treated with monoisoamyl-2,3-dimercaptosuccinate] results in decreased expression of MATN1 mRNAaffects cotreatment|decreases expression 19615344
C017947 sodium arsenite sodium arsenite results in decreased expression of MATN1 mRNAdecreases expression 19615344
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma arsenic trioxide 4.5411798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.5420127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.806695378
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 5.1415276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.3516712894 17306315
MESH:D000382 Agricultural Workers' Diseases Atrazine 4.6211874814
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.4319183758
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 3.9516206674
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0017474063 20146248
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.6311589617
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 3.2115553829 14691202 15073043 16217749 11135700
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 3.2115276417 17306315 16507464
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.3219014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.3812490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.8220419170
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.8218572023
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 3.6916936243
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 3.1720056578 19524636
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.5112609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.4015213294
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.6312903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.6316530937
MESH:D005234 Fatty Liver arsenic trioxide 3.5715073043
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.5916904648
MESH:D005833 Genital Neoplasms, Female sodium arsenite 5.0816452187
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.7820471113
MESH:D006689 Hodgkin Disease sodium arsenite 3.4012676792
MESH:D007248 Infertility, Male Atrazine 7.6812948887
MESH:D007248 Infertility, Male sodium arsenite 7.6812646999 15346721
MESH:D007674 Kidney Diseases sodium arsenite 2.9420008137
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 4.5616518626
MESH:D007938 Leukemia arsenic trioxide 2.9515070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.0817077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.7016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.6314633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.0419077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1716467208 17050201 20471514 16968895 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.3812712474 12018890 19642359 17649720 19035177 15622746 15213294 15748426 16891316 16823087 17712046 19225113 9834237 17869043 17107899 16330433 19075265 17217047 16112521 16331271 11468182 11161223 16966277 15336539 12679006
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.6816882451
MESH:D008113 Liver Neoplasms arsenic trioxide 7.9914682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 7.9921137059 20195826
MESH:D008113 Liver Neoplasms sodium arsenite 7.9915276417 16712894
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 2.8920377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.5615213294
MESH:D008171 Lung Diseases sodium arsenite 3.3519095001
MESH:D008175 Lung Neoplasms arsenic trioxide 3.5911798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 3.5918816296 20064080 18569708 20135361 20464547 20869020 18520028 6695378 17053015
MESH:D008175 Lung Neoplasms sodium arsenite 3.5916712894 17077188 17306315 19931552 15276417
MESH:D008545 Melanoma sodium arsenite 2.0619082730 16487513
MESH:D008654 Mesothelioma Atrazine 3.621916698
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4016381670
MESH:D009101 Multiple Myeloma arsenic trioxide 3.2915949261 14977855 19549372 11468182 19417148
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.1218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.2816882451 16105982
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.2916624393
MESH:D009369 Neoplasms Benzo(a)pyrene 5.4311141357
MESH:D009369 Neoplasms sodium arsenite 5.4311559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 4.0220056578
MESH:D009436 Neural Tube Defects arsenic trioxide 7.9010525206
MESH:D009436 Neural Tube Defects sodium arsenite 7.9012854658
MESH:D010051 Ovarian Neoplasms arsenic trioxide 5.1519769630 12452020 16624393
MESH:D010051 Ovarian Neoplasms sodium arsenite 5.1517306315 15276417
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6015580305
MESH:D010212 Papilloma Hydrogen Peroxide 4.4412065085
MESH:D010235 Paraganglioma arsenic trioxide 4.4719927285
MESH:D010300 Parkinson Disease Atrazine 3.3617218051
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.5019131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.5017292933
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.5016039940
MESH:D012135 Respiratory Sounds Atrazine 4.8711874814
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.2916646077
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 10.2119755658 10029692
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 10.2112065085
MESH:D012878 Skin Neoplasms sodium arsenite 10.2119524636 18572023
MESH:D016135 Spinal Dysraphism sodium arsenite 4.0112854658
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.4217007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.4220155912 2093021
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.2919014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.3615213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.8612845720 20435036 12973940 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.8617053015
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.8617306315 16712894 11723127 16452187
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 4.0311813266
MESH:D014652 Vascular Diseases sodium arsenite 4.8217056641
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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