AutismKB 2.0

Annotation Detail for FAM116B


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Basic Information Top
Gene Symbol:FAM116B ( MGC33692 )
Gene Full Name: family with sequence similarity 116, member B
Band: 22q13.33
Quick LinksEntrez ID:414918; OMIM: NA; Uniprot ID:F116B_HUMAN; ENSEMBL ID: ENSG00000205593; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of FAM116B mRNAaffects expression 17562736
D002117 Calcitriol Calcitriol results in increased expression of FAM116B mRNAincreases expression 16002434
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in decreased expression of FAM116B mRNAdecreases expression 18087596
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 6.4015814487
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 3.2619898480
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D001943 Breast Neoplasms Calcitriol 2.5611237771
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 3.5411212258
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 5.4511237771
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 5.4511212258
MESH:D002386 Cataract Acetaminophen 2.8110977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6812594235 10915739 10663392 17906064 11739529 18071297 19923254 12705907 15619225 11287661 16393943 19416960 12540782 16781746 19370779 19085960 11529661 15968718 12153990 14986274 17562736 16177239 11834606 14725611 16227642 11421492 19420014 19739265 19164858 12958197 11743745 17522070 18713872 16081117 16485898 11461765 2444490 16109766 10774834 14550746 12392966
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 4.5215138306
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.0616870215
MESH:D007249 Inflammation Tobacco Smoke Pollution 3.5318590791
MESH:D007674 Kidney Diseases Acetaminophen 2.4215629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7112587719 12969438 11587558 16610002 19460945 16611625 19014921 19784758
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6816871587 17185352
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 2.7316288123 12111688 11091918 3440675
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 4.6915006635
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D010146 Pain Acetaminophen 2.7716870215
MESH:D011470 Prostatic Hyperplasia Calcitriol 5.5215572423
MESH:D011471 Prostatic Neoplasms Calcitriol 3.4815754350 16289102 16644109 12479363 18247401
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 5.2718410779
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 3.7018590791
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 3.4712846360
MESH:D014581 Urticaria Acetaminophen 3.5010982225
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018