AutismKB 2.0

Annotation Detail for MBD1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MBD1 ( CXXC3,PCM1,RFT )
Gene Full Name: methyl-CpG binding domain protein 1
Band: 18q21.1
Quick LinksEntrez ID:4152; OMIM: 156535; Uniprot ID:MBD1_HUMAN; ENSEMBL ID: ENSG00000141644; HGNC ID: 6916
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2047Rett syndrome
2124Autistic disorder
Desease Name
CANCER
Chronic lymphocytic leukemia
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of MBD1 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of MBD1 mRNAaffects expression 17562736
D001151 Arsenic Arsenic results in decreased expression of MBD1 mRNAdecreases expression 19654921
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of MBD1 mRNAaffects expression 17484886
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in decreased expression of MBD1 mRNAdecreases expression 16934159
D016572 Cyclosporine Cyclosporine results in increased expression of MBD1 mRNAincreases expression 20106945
C014347 decitabine decitabine results in increased expression of MBD1 mRNAincreases expression 19329758
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of MBD1 mRNAincreases expression 19100860
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of MBD1 mRNAdecreases expression 17475347
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MBD1 mRNAaffects cotreatment|increases expression 17942748
D005038 Ethylnitrosourea Ethylnitrosourea results in increased expression of MBD1 mRNAincreases expression 19100860
D010126 Ozone TTPA protein affects the reaction [Ozone results in increased expression of MBD1 mRNA]affects reaction|increases expression 19555225
D010269 Paraquat Paraquat results in increased expression of MBD1 mRNAincreases expression 12595580
D010634 Phenobarbital Phenobarbital results in decreased expression of MBD1 mRNAdecreases expression 19270015
C006253 pirinixic acid pirinixic acid results in increased expression of MBD1 mRNAincreases expression 18445702
D012643 Selenium Selenium results in decreased expression of MBD1 mRNAdecreases expression 19244175
C017947 sodium arsenite sodium arsenite results in increased expression of MBD1 mRNAincreases expression 19822182
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MBD1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of MBD1 mRNAincreases expression 17942748
D014810 Vitamin E Vitamin E results in decreased expression of MBD1 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 8.186195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.1815322242 11752688 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9117505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.0818653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8014692618
MESH:D000236 Adenoma Diethylnitrosamine 6.9410737359 6695378
MESH:D000236 Adenoma Ethylnitrosourea 6.946695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 24.5918056438 17162532 17620307 19061943 19052882 16434500
MESH:D018248 Adenoma, Liver Cell Phenobarbital 24.5917620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 24.5916434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 24.5916835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.6715276417
MESH:D018246 Adrenocortical Adenoma Arsenic 13.7017306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 13.7017306315 16712894
MESH:D000382 Agricultural Workers' Diseases Paraquat 3.7311874814
MESH:D000544 Alzheimer Disease Ozone 2.4315513908
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9111748828
MESH:D000799 Angioedema Acetaminophen 3.8110982225
MESH:D020261 Arsenic Poisoning Arsenic 2.8512569548 16835338 18414634 16251483
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6415885639
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5515570426
MESH:D001249 Asthma Ozone 2.6216373670 17854713
MESH:D050197 Atherosclerosis Arsenic 3.2212928151 19371607
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.6319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.6312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7315746008
MESH:D001927 Brain Diseases Ethylnitrosourea 4.8414991843
MESH:D001932 Brain Neoplasms Ethylnitrosourea 4.2516436596 16651633 16357521 15144691 18412241
MESH:D001943 Breast Neoplasms decitabine 1.8718320071 19208741
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.8717474063
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8720435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.6418315731 17626835 15516495 19059883 18417511 16777450 14754758
MESH:D002100 Cachexia Ozone 4.7016183385
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 9.8016192424 15721981 16097048 3786805 18705752 15700767 10355542 15673190 16124888 16227642 16050911 16011737
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 9.8016050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7616835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.5715504454 17687452
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 14.0016705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 14.003084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 14.0017306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 14.0018788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 14.0017428255 19539802 18971187 3084413 20007298 18210153 18691550 19394651 20935162 16502159 16807293 18506893 10737359 19335982 20214788 16328049 21159647 19919837 20101231 19701751 17162532 20084675 11831363 17761372 16698587 18788625 20512989 3581430 18785209 19052882 19418558 20514400 19107877 19519916 18494052 16878318 18978308 17173139 20524982 16288022 16830150 17138121 19822196 19171122 19383236 20727157 18056438 17978847 19208518 18393292 20432363 17055752 16935385 10672840 16569478 16681979 16540662 16779866 18665156
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 14.0017173139 1701930 20935162 6705139 20007298
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 14.0015276417 17306315 16507464
MESH:D002294 Carcinoma, Squamous Cell Arsenic 7.5718922899 17687452 15504454
MESH:D002294 Carcinoma, Squamous Cell decitabine 7.5719215824
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 7.5718572023
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.0418640142
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3416120746 18850075 18670907
MESH:D002318 Cardiovascular Diseases Arsenic 3.4217938729 15738583 19152805
MESH:D002340 Carotid Artery Diseases Arsenic 4.2718022660 16973168
MESH:D002386 Cataract Acetaminophen 2.5510977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 15.8212371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 15.8217174075 21159647 7505956 2727394
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 15.8216003739
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 15.8220056578 19524636
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.214080065
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 5.9617160924
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.2019052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.2016835633
MESH:D002779 Cholestasis Cyclosporine 13.1519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.1516919318 11677210 17681005 15861022 16105132 17333356 17110522
MESH:D002779 Cholestasis pirinixic acid 13.1519176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0812621046 8697196 16354765 15668235 15340226
MESH:D003092 Colitis Selenium 3.7417936198
MESH:D003110 Colonic Neoplasms decitabine 2.3317616700
MESH:D015179 Colorectal Neoplasms decitabine 2.1018981723
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0217141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4715322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.4719769572
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.9718551238
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4018249437
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.1820387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.1817107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 18.5118551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 18.5110774834 17906064 15619225 12153990 2444490 19085960 19923254 16177239 16109766 18071297 17562736 12705907 16393943 15968718 19370779 16227642 11743745 12958197 11739529 19416960 19420014 17522070 12540782 11461765 14550746 11421492 16081117 11834606 16485898 19739265 11529661 16781746 12594235 14725611 12392966 14986274 19164858 10915739 10663392 11287661 18713872
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 18.514309450 11566570 16177239 3786805 17522070 3732212 9327722 6884620 21278145 10092053 2869522 7179309 10915739 15027814 19085960 19336974 7440962 7120509 15968718 6623471 16227642 15998439
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 18.5117851650
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 18.5119107877
MESH:D056486 Drug-Induced Liver Injury Selenium 18.5115131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 18.5120420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7311462148
MESH:D004421 Dystonia Phenobarbital 3.961851702
MESH:C538011 Eales disease Vitamin E 4.689068938
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 5.9618357618
MESH:D004487 Edema pirinixic acid 6.4012083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.4012711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8718230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.1512538720
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.0919294695
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.989294722 10568697
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.073659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.843922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.8720417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.506401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.217750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.983659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0916302075
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9811564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 24.2112631006 19224547 12795759 61145 15959796 16239168 17595544 16045604
MESH:D005234 Fatty Liver Cyclosporine 24.2119224547
MESH:D005234 Fatty Liver Diethylnitrosamine 24.2121071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 24.2115345470
MESH:D005234 Fatty Liver pirinixic acid 24.2120131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4211858732
MESH:D005355 Fibrosis Carbon Tetrachloride 14.4918705752
MESH:D005355 Fibrosis Cyclosporine 14.4912639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.4920067830
MESH:D005534 Foot Diseases Arsenic 5.536392382
MESH:D005756 Gastritis Acetaminophen 3.6516983495
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.6416452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.188708960
MESH:D005909 Glioblastoma Ethylnitrosourea 3.8016436596
MESH:D005910 Glioma Ethylnitrosourea 3.4716651633 16357521 18412241
MESH:D005911 Gliosis Paraquat 5.1411124998
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5710696789
MESH:D006258 Head and Neck Neoplasms decitabine 3.4619215824
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.4910048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 6.4916080930
MESH:D006333 Heart Failure pirinixic acid 6.8620558911
MESH:D006333 Heart Failure Selenium 6.8617162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2911000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.5519110552 19900420
MESH:D006529 Hepatomegaly Phenobarbital 14.1616109766
MESH:D006529 Hepatomegaly pirinixic acid 14.1619772884 19176532 18467677 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 14.1616120746 15340226 12621046
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6916863852 16490937
MESH:D006689 Hodgkin Disease sodium arsenite 3.1112676792
MESH:D019584 Hot Flashes Vitamin E 3.9414716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0218606429 8697196 16354765 15340226 16959395
MESH:D006930 Hyperalgesia Acetaminophen 2.6616870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.5016899240
MESH:D006943 Hyperglycemia pirinixic acid 3.1420558911
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.4217050553
MESH:D006973 Hypertension Arsenic 8.4916076760 11953799 9931084
MESH:D006973 Hypertension Cyclosporine 8.4910903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.4918670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.0515338365
MESH:D006987 Hypesthesia Arsenic 5.5316093927
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7716569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4212013081
MESH:D007248 Infertility, Male decitabine 15.8217581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 15.8217937319
MESH:D007248 Infertility, Male Paraquat 15.824850670
MESH:D007248 Infertility, Male sodium arsenite 15.8212646999 15346721
MESH:D007249 Inflammation Diethylnitrosamine 4.8218785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.8212878042 12200463
MESH:D007251 Influenza, Human Selenium 10.8616624496
MESH:D007251 Influenza, Human Vitamin E 10.8616624496
MESH:D007333 Insulin Resistance pirinixic acid 2.6016306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2916580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.4115604871
MESH:D007642 Keratosis Arsenic 4.9512749816 16930632
MESH:D007674 Kidney Diseases Acetaminophen 14.2212587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 14.2218776723 10903974 8314463
MESH:D007674 Kidney Diseases sodium arsenite 14.2220008137
MESH:D007674 Kidney Diseases Vitamin E 14.2212488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.8416518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 12.2816705839
MESH:D007680 Kidney Neoplasms Cyclosporine 12.2812371664
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 12.2817379185
MESH:D007938 Leukemia decitabine 3.0518980019 19235587
MESH:D007951 Leukemia, Myeloid decitabine 3.9619117987 17236224 18454857
MESH:D015470 Leukemia, Myeloid, Acute decitabine 2.3718206229 19010910 18704418 17679729 19387464 18460780
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.4318055864
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.5217339181
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.8811408273 17334410 16943688 17157831 16239168 16221502 21278145 17174718 11903743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.8820032147 19638242 18665156 18407596 18522880
MESH:D008103 Liver Cirrhosis Phenobarbital 10.8821047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.8818317297 18481824 17805973 15123356 14716496 17761835 14748882 16027843 14620537 17900296 16116963 12445421 12666154 18395095 15818738 15876570 16248980 16033810 17714472 16097048 16638106 18420326 17922224 12586293 18166357 16192424 16015684 12609069 17698563 18339082 12546737 17640975 18054572 12667390 12445418 15362042 15931870 11481614 15370692 17631135 15057751 17525996 17823541 14716833 18395914 17976157 18210741 12958196 18705752 18205269 18472094 16011737 14512876 20821823 18277467 15959796 17557913 18279442 12389079 12741479 18006644 15996030 17944888 15893842 17565644 17721639 15925388 18156304 12898905 17766677 18376398 15052691 12649538 18187930 17481882 18429990 18412020 18263696 18251166 13678700 17869086 17708605 18472332 18418968 16136751 14724832 12632514 10355542 15673190 15650968 15730626 12632512 15338365
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.8815474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.8812878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.8816169303
MESH:D008107 Liver Diseases Acetaminophen 12.4219460945 16611625 19784758 12587719 19014921 16610002 12969438 11587558
MESH:D008107 Liver Diseases Arsenic 12.4211134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 12.4216246199 15830285 16964402 15720792 17285989
MESH:D008107 Liver Diseases Diethylnitrosamine 12.4217034775
MESH:D008107 Liver Diseases Phenobarbital 12.4219363144
MESH:D017093 Liver Failure Carbon Tetrachloride 4.1215123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.2816871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.2816899240 14706259
MESH:D008113 Liver Neoplasms Arsenic 21.6716368122
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 21.6719294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 21.6719427195 20492335 19551842 12112319 15175105 20452335 19642983 19812893 20434301 18754104 16942905 10737359 18978307 20405173 20501860 19426721 19256749 21278145 18977376 19294768 18648771 19499222 19996281 19638242 15885732 12771043 21167192 20137499 19254457 19690152 9163691 18644402 21047994 20101389 2862719 2422723 19090486 19073162 19255062 19850985 20118626 20583210 19833225 21071580
MESH:D008113 Liver Neoplasms Phenobarbital 21.6719812893 21047994 8742319 15975961 19073162 19482888
MESH:D008113 Liver Neoplasms pirinixic acid 21.6720007298 15890375 16377806
MESH:D008113 Liver Neoplasms sodium arsenite 21.6716712894 15276417
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 21.6716984957
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 13.8812014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.8818308698 19009564 18253720 17942915 9362446 16267830 18093689 18544905 19519916 18775883 17174075 18079962 2563599 3124819 16842330 19539802 17854601 19126423 21159647 18164116 19004024 18282651
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 13.886150874 17172636 2563599 1399818 18308698
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.8812151625
MESH:D008171 Lung Diseases Ozone 12.2019066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 12.2019095001
MESH:D008171 Lung Diseases Vitamin E 12.2016863852
MESH:D055370 Lung Injury Ozone 3.8120417186
MESH:D008175 Lung Neoplasms Arsenic 10.6417976673 17306315 19168569
MESH:D008175 Lung Neoplasms Diethylnitrosamine 10.6421163286 6695378 20970405 20512841
MESH:D008175 Lung Neoplasms Ethylnitrosourea 10.6417703301 16019985 6695378 16271038
MESH:D008175 Lung Neoplasms Ozone 10.648597069 7614698
MESH:D008175 Lung Neoplasms sodium arsenite 10.6416712894 17077188 17306315 19931552 15276417
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 10.6411884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 10.6411062179
MESH:D008223 Lymphoma decitabine 7.8019470736
MESH:D008223 Lymphoma Ethylnitrosourea 7.8015790496
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 5.0115375218
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 6.2718041768 10767621 10838139
MESH:D008325 Mammary Neoplasms, Experimental Selenium 6.2715318939
MESH:D008545 Melanoma decitabine 3.4317785578 16505122
MESH:D008545 Melanoma sodium arsenite 3.4316487513 19082730
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5319513568
MESH:D008579 Meningioma Ethylnitrosourea 5.9617943659
MESH:D008654 Mesothelioma Selenium 2.7715107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7616801185
MESH:D008679 Metaplasia Ozone 5.0810496685
MESH:D009101 Multiple Myeloma decitabine 3.3118172295
MESH:D009135 Muscular Diseases pirinixic acid 3.4716239165
MESH:D009190 Myelodysplastic Syndromes decitabine 3.3619010910 16882708 18608210 19157545
MESH:D009203 Myocardial Infarction pirinixic acid 2.1219151258
MESH:D017202 Myocardial Ischemia Arsenic 8.8815371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.8812213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9116411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.4417484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.8218551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.559029167 3581430
MESH:D009369 Neoplasms decitabine 8.1519116145 19470736 17925555
MESH:D009369 Neoplasms pirinixic acid 8.1517405874
MESH:D009369 Neoplasms sodium arsenite 8.1511559025
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 9.2416707424
MESH:D009374 Neoplasms, Experimental sodium arsenite 9.2420056578
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.4117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2419348381 18481113
MESH:D009410 Nerve Degeneration Paraquat 3.6816893418
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.1714600291
MESH:D009436 Neural Tube Defects Arsenic 7.3616620997
MESH:D009436 Neural Tube Defects sodium arsenite 7.3612854658
MESH:D009442 Neurilemmoma Ethylnitrosourea 5.3816003739 17160924 16651423
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.0618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.0620387270
MESH:D020078 Neurogenic Inflammation Arsenic 4.3317056641
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0920387270
MESH:D009765 Obesity pirinixic acid 1.8020558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.3916049721 12819281
MESH:D009837 Oligodendroglioma Ethylnitrosourea 5.9617160924
MESH:D010018 Osteomalacia Phenobarbital 4.3317016548
MESH:D010051 Ovarian Neoplasms Arsenic 7.9117306315
MESH:D010051 Ovarian Neoplasms decitabine 7.9119259094 19331143
MESH:D010051 Ovarian Neoplasms sodium arsenite 7.9115276417 17306315
MESH:D010146 Pain Acetaminophen 2.3516870215
MESH:D010190 Pancreatic Neoplasms decitabine 8.5619294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.5616540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 8.5616965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6511578682
MESH:D010300 Parkinson Disease Paraquat 2.8012911755 15451049 11445065 11181820 15824117 11124998 16140633 16510128
MESH:D010302 Parkinson Disease, Secondary Paraquat 4.3916190885
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2212520081
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.1416093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.9516905509 6392382 15371236
MESH:D010538 Peritonitis Ozone 4.0916369182
MESH:D010954 Plasmacytoma Selenium 4.8615087411
MESH:D011014 Pneumonia Ozone 10.9518007984 18929643 18381685
MESH:D011014 Pneumonia Paraquat 10.9512504350
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5218163543
MESH:D011230 Precancerous Conditions Cyclosporine 15.0512371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 15.052563599
MESH:D011230 Precancerous Conditions Phenobarbital 15.052563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.1611896295 11222880 11399792 11118676
MESH:D055728 Primary Myelofibrosis decitabine 4.6917616702
MESH:D011471 Prostatic Neoplasms Arsenic 2.6516140617
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.6516039940
MESH:D011471 Prostatic Neoplasms Vitamin E 2.6515084515
MESH:D011507 Proteinuria Arsenic 3.9621343184
MESH:D011537 Pruritus Ethinyl Estradiol 3.2816919318 15861022
MESH:D019310 Pseudolymphoma Phenobarbital 4.4712752131
MESH:D011565 Psoriasis Cyclosporine 2.2116882103
MESH:D011658 Pulmonary Fibrosis Paraquat 2.9016324872 17997886
MESH:D015427 Reperfusion Injury pirinixic acid 2.3619058328
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 3.8611700416
MESH:D012135 Respiratory Sounds Paraquat 4.0211874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8018990726
MESH:D012162 Retinal Degeneration Paraquat 3.8316458197
MESH:D012208 Rhabdomyosarcoma decitabine 4.3619155313
MESH:D012640 Seizures 2,4-dinitrotoluene 5.8218551238
MESH:D012640 Seizures Phenobarbital 5.823137016 11442880 4039156 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.796407741
MESH:D012871 Skin Diseases Arsenic 5.0016353154 18709164 6392382 16759981 17050553 17548696 19834688 17453740 17938729 15952646 16702368
MESH:D012871 Skin Diseases Vitamin E 5.0018709164
MESH:D012878 Skin Neoplasms Arsenic 9.3717029826 15504454 17976673 16251483 17050553 19538983
MESH:D012878 Skin Neoplasms sodium arsenite 9.3719524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.3716192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.9116709447
MESH:D016135 Spinal Dysraphism sodium arsenite 3.7612854658
MESH:D013274 Stomach Neoplasms decitabine 2.5219037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.5218456281
MESH:D020521 Stroke Vitamin E 3.4816517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1115669648
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 5.1215790496
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8712697716
MESH:D013964 Thyroid Neoplasms decitabine 11.8217967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 11.827505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 11.821399818
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 11.8316049721
MESH:D001749 Urinary Bladder Neoplasms Arsenic 11.8317976673 11144890 18640142 15987713 19429237 17306315 19322015
MESH:D001749 Urinary Bladder Neoplasms decitabine 11.8317616700 19087683
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 11.8316452187 11723127 16712894 17306315
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.2810091137
MESH:D014581 Urticaria Acetaminophen 2.9410982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.7311813266
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2614692618
MESH:D014604 Uveal Neoplasms decitabine 4.8817785578
MESH:D014605 Uveitis Cyclosporine 3.961336536
MESH:D014652 Vascular Diseases Arsenic 11.7317056641
MESH:D014652 Vascular Diseases sodium arsenite 11.7317056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5015869587 14671159
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2215886252
MESH:D014985 Xerophthalmia Cyclosporine 4.4117120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved