AutismKB 2.0

Annotation Detail for MCM4


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Basic Information Top
Gene Symbol:MCM4 ( CDC21,CDC54,MGC33310,P1-CDC21,hCdc21 )
Gene Full Name: minichromosome maintenance complex component 4
Band: 8q11.21
Quick LinksEntrez ID:4173; OMIM: 602638; Uniprot ID:MCM4_HUMAN; ENSEMBL ID: ENSG00000104738; HGNC ID: 6947
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa03030DNA replication
hsa04110Cell cycle
Pathway IDPathway Name
Cell Cycle, Mitotic
DNA Replication
Cell Cycle Checkpoints
Pathway IDPathway Name
200130C-MYB transcription factor network
No data
Pathway IDPathway Name
500964Removal of licensing factors from origins
500932Switching of origins to a post-replicative state
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2257Hemolytic-Uremic syndrome
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C027576 4-hydroxy-2-nonenal 4-hydroxy-2-nonenal results in decreased expression of MCM4 mRNAdecreases expression 12419474
C006632 arsenic trioxide arsenic trioxide results in increased expression of MCM4 mRNAincreases expression 20458559
C006632 arsenic trioxide arsenic trioxide results in increased expression of MCM4 proteinincreases expression 19364129
D001205 Ascorbic Acid [Quercetin co-treated with Ascorbic Acid] results in increased expression of MCM4 mRNAaffects cotreatment|increases expression 17639512
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MCM4 mRNAdecreases expression 20382639
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of MCM4 mRNAdecreases expression 12419474
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of MCM4 mRNAaffects expression 17484886
D003345 Corticosterone Corticosterone results in decreased expression of MCM4 mRNAdecreases expression 15755911
C030123 coumarin coumarin results in increased expression of MCM4 mRNAincreases expression 18480146
D016572 Cyclosporine Cyclosporine results in decreased expression of MCM4 mRNAdecreases expression 20106945
C014347 decitabine decitabine affects the methylation of MCM4 geneaffects methylation 17630775
D004041 Dietary Fats Dietary Fats results in increased expression of MCM4 mRNAincreases expression 18042831
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of MCM4 mRNAincreases expression 17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MCM4 mRNA]decreases reaction|increases expression 17854601
D004317 Doxorubicin Doxorubicin affects the expression of MCM4 mRNAaffects expression 15205334
C007610 equol equol results in decreased expression of MCM4 mRNAdecreases expression 16865672
D004958 Estradiol Estradiol affects the expression of MCM4 mRNAaffects expression 15598610
D004958 Estradiol [Progesterone co-treated with Estradiol] results in decreased expression of MCM4 proteinaffects cotreatment|decreases expression 16966611
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of MCM4 mRNAdecreases expression 17555576
D005472 Fluorouracil Fluorouracil affects the expression of MCM4 mRNAaffects expression 15205334
D006851 Hydrochloric Acid Hydrochloric Acid results in increased expression of MCM4 mRNAincreases expression 15046208
D006861 Hydrogen Peroxide Hydrogen Peroxide results in decreased expression of MCM4 mRNAdecreases expression 12419474
C051890 irinotecan irinotecan metabolite results in decreased expression of MCM4 mRNAdecreases expression 15956246
C051890 irinotecan irinotecan results in decreased expression of MCM4 mRNAdecreases expression 15956246
D008345 Manganese Manganese results in decreased expression of MCM4 mRNAdecreases expression 17175027
C025340 manganese chloride manganese chloride results in decreased expression of MCM4 mRNAdecreases expression 17175027
D008713 Methimazole Methimazole results in decreased expression of MCM4 mRNAdecreases expression 17403546
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of MCM4 mRNAincreases expression 20713471
D008769 Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in decreased expression of MCM4 mRNAdecreases expression 12634122
D010100 Oxygen Oxygen deficiency results in decreased expression of MCM4 mRNAdecreases expression 17175027
C041786 palm oil palm oil results in increased expression of MCM4 mRNAincreases expression 18042831
C494474 perchlorate perchlorate results in decreased expression of MCM4 mRNAdecreases expression 17403546
D010634 Phenobarbital Phenobarbital results in increased expression of MCM4 mRNAincreases expression 19136022
19363144
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of MCM4 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of MCM4 mRNAincreases expression 19136022
18301758
17950772
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of MCM4 mRNA]increases expression|increases reaction 17950772
D011374 Progesterone [Progesterone co-treated with Estradiol] results in decreased expression of MCM4 proteinaffects cotreatment|decreases expression 16966611
D011374 Progesterone Progesterone results in decreased expression of MCM4 mRNAdecreases expression 16966611
D011441 Propylthiouracil Propylthiouracil results in decreased expression of MCM4 mRNAdecreases expression 17403546
D011794 Quercetin [Quercetin co-treated with Ascorbic Acid] results in increased expression of MCM4 mRNAaffects cotreatment|increases expression 17639512
C059514 resveratrol resveratrol results in decreased expression of MCM4 mRNAdecreases expression 15767336
D012402 Rotenone Rotenone results in increased expression of MCM4 mRNAincreases expression 19013527
C496197 trans-10,cis-12-conjugated linoleic acid trans-10,cis-12-conjugated linoleic acid results in decreased expression of MCM4 mRNAdecreases expression 17951470
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 3.086195326
MESH:D000138 Acidosis Hydrochloric Acid 4.8320872349 19262391 12771618 16144966 11574821 15920416
MESH:D000141 Acidosis, Renal Tubular Hydrochloric Acid 5.4117183249
MESH:D000142 Acidosis, Respiratory Hydrochloric Acid 5.4420597076
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5717505938
MESH:D058186 Acute Kidney Injury resveratrol 3.5316538975
MESH:D055371 Acute Lung Injury Hydrochloric Acid 13.5016759491 11850527 19060228 19760209 15970105 11953099 19094174
MESH:D055371 Acute Lung Injury Oxygen 13.5016759491
MESH:D055371 Acute Lung Injury pirinixic acid 13.5018653653
MESH:D000230 Adenocarcinoma arsenic trioxide 12.4319825857 11798837
MESH:D000230 Adenocarcinoma Doxorubicin 12.4317418594
MESH:D000230 Adenocarcinoma Estradiol 12.4311473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 12.4314692618
MESH:D000230 Adenocarcinoma Fluorouracil 12.4317638652
MESH:D000236 Adenoma Diethylnitrosamine 10.0610737359 6695378
MESH:D000236 Adenoma Methylcholanthrene 10.066695378 10545420
MESH:D000236 Adenoma resveratrol 10.0615688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 15.2219061943 17162532 17620307 16434500 19052882 18056438
MESH:D018248 Adenoma, Liver Cell Phenobarbital 15.2217620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 15.2216434500
MESH:D000419 Albuminuria Doxorubicin 4.1921441931
MESH:D000544 Alzheimer Disease resveratrol 2.4916162502 16183991
MESH:D000690 Amyotrophic Lateral Sclerosis 4-hydroxy-2-nonenal 3.8710965797
MESH:D000740 Anemia Fluorouracil 3.4015504547 17963324 16511603
MESH:D000743 Anemia, Hemolytic Quercetin 3.9117084956
MESH:D000756 Anemia, Sideroblastic Manganese 9.9416910769
MESH:D000756 Anemia, Sideroblastic manganese chloride 9.9416910769
MESH:D000860 Anoxia Hydrochloric Acid 10.4015090967
MESH:D000860 Anoxia Oxygen 10.4020872349
MESH:D001161 Arteriosclerosis Dietary Fats 8.7115238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.7111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.6015885639
MESH:D001169 Arthritis, Experimental resveratrol 6.6017115116
MESH:D001260 Ataxia Telangiectasia Quercetin 4.6115336622
MESH:D050197 Atherosclerosis Methylcholanthrene 9.9111922910
MESH:D050197 Atherosclerosis Oxygen 9.9116391483
MESH:D050197 Atherosclerosis resveratrol 9.9116873680 17967414
MESH:D001327 Autoimmune Diseases Quercetin 4.0519761891
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 19.3716206674
MESH:D001778 Blood Coagulation Disorders Hydrochloric Acid 19.3715920416
MESH:D001778 Blood Coagulation Disorders pirinixic acid 19.3719483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 19.3719483382
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.3214601052
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.9617868700
MESH:D001930 Brain Injuries Progesterone 3.9015665606 15845082 15380490
MESH:D002545 Brain Ischemia resveratrol 3.9217600658
MESH:D001932 Brain Neoplasms Doxorubicin 3.4917150277
MESH:D001943 Breast Neoplasms Ascorbic Acid 10.5516443354
MESH:D001943 Breast Neoplasms decitabine 10.5518320071 19208741
MESH:D001943 Breast Neoplasms Dietary Fats 10.5520435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 10.5517474063
MESH:D001943 Breast Neoplasms Doxorubicin 10.5516264153 15939500 15136595 17369602 19526202 11325840 18628466 16595493 17983394 18382427 18695136 15634643 16096432 15993339 15692762 15567936 16322301 16935488 17426702 16826403 15994142 15668708 18234424 16115903
MESH:D001943 Breast Neoplasms equol 10.5516898868
MESH:D001943 Breast Neoplasms Estradiol 10.5517289903 18497071 12948864 16675129 14630087 17018787 17261762 19861407
MESH:D001943 Breast Neoplasms Fluorouracil 10.5519217205 16595493 15136595 16110121 16557594 18357371 18608205
MESH:D001943 Breast Neoplasms Methylcholanthrene 10.5517474063
MESH:D001943 Breast Neoplasms Oxygen 10.5517263869
MESH:D001943 Breast Neoplasms Progesterone 10.5516175315 15562024 17614352
MESH:D001943 Breast Neoplasms Quercetin 10.5518628248
MESH:D001943 Breast Neoplasms resveratrol 10.5517534123 17651959 16393696
MESH:D016535 Bronchial Hyperreactivity Hydrochloric Acid 4.3012378975
MESH:D001986 Bronchial Spasm Hydrochloric Acid 5.0915578804
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.9911589617
MESH:D002105 Cadmium Poisoning Quercetin 5.1716962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0916111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.4210355542 15721981 16050911 16011737 16097048 16124888 16192424 16227642 18705752 15673190 3786805 15700767
MESH:D002276 Carcinoid Tumor Doxorubicin 11.1016051944
MESH:D002276 Carcinoid Tumor Fluorouracil 11.1016051944
MESH:D002277 Carcinoma Fluorouracil 7.6617121937
MESH:D002277 Carcinoma Methylcholanthrene 7.6610545420
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 18.5411135700 16217749 15553829 14691202 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 18.5418788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 18.5417978847 17162532 17173139 19418558 17138121 16779866 16288022 19383236 19171122 19335982 19208518 19822196 16328049 20512989 10672840 16540662 16878318 16681979 16569478 16807293 19919837 20084675 18788625 16698587 19701751 16830150 18210153 3581430 18506893 10737359 20727157 19519916 19539802 18665156 19052882 18978308 16502159 21159647 20214788 20007298 18393292 20432363 3084413 18971187 17055752 20524982 20514400 11831363 16935385 17761372 18785209 19107877 20101231 18494052 17428255 20935162 18056438 19394651 18691550
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 18.5418059187 16023760 16234567 17876044
MESH:D006528 Carcinoma, Hepatocellular Estradiol 18.5416924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 18.5417971768 16332177 18930000 17088986 16799960 17045692
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 18.5417173139 20007298 6705139 1701930 20935162
MESH:D006528 Carcinoma, Hepatocellular Quercetin 18.5419519916 12508355
MESH:D006528 Carcinoma, Hepatocellular resveratrol 18.5416227395 19321006
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.2216675471
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.6017234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.5019014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.0816201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 6.0818695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.8012490120
MESH:D002294 Carcinoma, Squamous Cell decitabine 9.8719215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 9.876189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 9.8716757204 17066447 16280240 18986760
MESH:D002294 Carcinoma, Squamous Cell resveratrol 9.8716227395
MESH:D006332 Cardiomegaly Quercetin 3.1119794523
MESH:D009202 Cardiomyopathies Doxorubicin 3.2916278810 17519947 17382496 16242529 17928571 16364871 16651473 16109756 16952015 17131338 17974986 15476868 16612575 18627295 15792986 17308081 17007740 15505089 17924179 17329180 15811867 17351982 16455267 16269455 16731534
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8117334414 16243910
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 6.7416936243
MESH:D002318 Cardiovascular Diseases resveratrol 6.7415458977
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 23.0720889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 23.0712371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 23.0717174075 7505956 21159647 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 23.0718566989
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 23.0716192471
MESH:D002471 Cell Transformation, Neoplastic Methylnitronitrosoguanidine 23.072727394
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.894080065
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.3819052882
MESH:D002779 Cholestasis Cyclosporine 11.7719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 11.7717681005 17333356 17110522 11677210 16919318 15861022 16105132
MESH:D002779 Cholestasis pirinixic acid 11.7719176532
MESH:D003092 Colitis resveratrol 3.7716474422
MESH:D003110 Colonic Neoplasms decitabine 10.2517616700
MESH:D003110 Colonic Neoplasms Fluorouracil 10.2516510598 17172411 18772588 17169374 17725105 17016597 15001691 16340194 17018589 17287894
MESH:D003110 Colonic Neoplasms irinotecan 10.2517725105 17287894
MESH:D003110 Colonic Neoplasms Quercetin 10.2511134977 15741050 16640504 19056647 19440933 17148506 17191121
MESH:D003110 Colonic Neoplasms resveratrol 10.2516338953
MESH:D015179 Colorectal Neoplasms arsenic trioxide 9.8520501625
MESH:D015179 Colorectal Neoplasms decitabine 9.8518981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 9.8518802399 18259882
MESH:D015179 Colorectal Neoplasms Fluorouracil 9.8516524972 16391804 17695437 18949393 16282729 17255274 16331619 15289873 20501625 18383874 15148649 17594712 18802399 14970324 17401013 17016601 18448328 17454858 16303861 17094418 18509181 18288408
MESH:D015179 Colorectal Neoplasms irinotecan 9.8516391804 17454858 17159606 16303861 15273666 18259882 18509181
MESH:D015179 Colorectal Neoplasms Quercetin 9.8518095365 18852136
MESH:D015179 Colorectal Neoplasms resveratrol 9.8516550006
MESH:D003139 Common Cold Ascorbic Acid 5.1017323712
MESH:D003327 Coronary Disease resveratrol 3.5116507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.8412609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8710525206
MESH:D003556 Cystitis Hydrochloric Acid 5.0912853844 20719367 12599022 19279288
MESH:D018856 Cystitis, Interstitial Hydrochloric Acid 5.4417714534
MESH:D007644 Darier Disease Fluorouracil 4.4216733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.7615213294
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2518249437
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 7.5719496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 7.5716873680
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 6.8016506275
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 6.8019647726
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.8020387270
MESH:D003928 Diabetic Nephropathies Estradiol 8.0019279558
MESH:D003928 Diabetic Nephropathies resveratrol 8.0016286809
MESH:D003929 Diabetic Neuropathies Progesterone 4.1317187935
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 5.627440962 6623471 4309450 6884620 15968718 7120509 2869522 9327722 10915739 3732212 16227642 3786805 16177239 15998439 21278145 19336974 19085960 11566570 17522070 7179309 15027814 10092053
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 5.6219107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 5.6217416283
MESH:D004362 Drug Toxicity Doxorubicin 3.4018602426
MESH:D050171 Dyslipidemias Dietary Fats 3.1918367378
MESH:D004417 Dyspnea Oxygen 4.4620016425
MESH:D004421 Dystonia Phenobarbital 3.671851702
MESH:C538011 Eales disease Ascorbic Acid 5.109068938
MESH:D004487 Edema pirinixic acid 5.8312083418
MESH:D004487 Edema resveratrol 5.838985016
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 13.3712538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 13.3717692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 13.3717872969
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.7419294695
MESH:D016889 Endometrial Neoplasms Doxorubicin 6.7417359293
MESH:D016889 Endometrial Neoplasms Estradiol 6.7419148513 11473722 18566989
MESH:D004715 Endometriosis Progesterone 3.4516134523
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.7818037988
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.4917923197
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.753659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.5011558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.7020417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.246401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.897750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.653659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.7416302075
MESH:D004935 Esophageal Diseases Hydrochloric Acid 5.4219566590
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.6520426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.6512903497
MESH:D004938 Esophageal Neoplasms Fluorouracil 6.6517638652 16785472 16481741 15173087 16337965
MESH:D004941 Esophagitis Hydrochloric Acid 5.6312928072
MESH:D004942 Esophagitis, Peptic Hydrochloric Acid 5.6420516732 11346197 14621274
MESH:D005234 Fatty Liver arsenic trioxide 31.9315073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 31.9315959796 61145 12795759 17595544 12631006 16239168 16045604 19224547
MESH:D005234 Fatty Liver Cyclosporine 31.9319224547
MESH:D005234 Fatty Liver Dietary Fats 31.9319004024 18296743 17967931 19551842
MESH:D005234 Fatty Liver Diethylnitrosamine 31.9321071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 31.9315345470
MESH:D005234 Fatty Liver pirinixic acid 31.9320131406 19236843
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.2219069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.5714633661 10962813
MESH:D005355 Fibrosis Carbon Tetrachloride 23.9518705752
MESH:D005355 Fibrosis Cyclosporine 23.9512639820 12168785
MESH:D005355 Fibrosis Dietary Fats 23.9518296743
MESH:D005355 Fibrosis Hydrochloric Acid 23.9518497604
MESH:D005355 Fibrosis Quercetin 23.9519474275
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.9116904648
MESH:D005739 Gas Poisoning Hydrochloric Acid 10.9512378975
MESH:D005739 Gas Poisoning Oxygen 10.9520016425
MESH:D005764 Gastroesophageal Reflux Hydrochloric Acid 4.9819957777 19951613 12212954 20516732 20616304 20545468
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.858708960
MESH:D005909 Glioblastoma Doxorubicin 10.6717150277
MESH:D005909 Glioblastoma Manganese 10.6717043766
MESH:D005909 Glioblastoma Quercetin 10.6719804834
MESH:D005910 Glioma Fluorouracil 5.6716145905
MESH:D005910 Glioma Quercetin 5.6717643826
MESH:D006042 Goiter perchlorate 4.9718801409
MESH:D006258 Head and Neck Neoplasms decitabine 11.5819215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 11.5815692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 11.5815162350 15102660 18337622
MESH:D006356 Heartburn Hydrochloric Acid 5.4219566590
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 3.5616080930
MESH:D006331 Heart Diseases Doxorubicin 3.2316495754 18674790 18006777 16707910 16144979 17875725 16879835 16330681 16244372 12587719 14766674 17888722 16244371
MESH:D006333 Heart Failure Doxorubicin 6.2917481944
MESH:D006333 Heart Failure pirinixic acid 6.2920558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.5715692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0515720958
MESH:D006505 Hepatitis Carbon Tetrachloride 3.2519110552 19900420
MESH:D006529 Hepatomegaly Phenobarbital 7.2916109766
MESH:D006529 Hepatomegaly pirinixic acid 7.2919772884 16221962 19176532 18467677
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 3.3416863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 4.6615709030
MESH:D006561 Herpes Simplex resveratrol 3.8116876885
MESH:D006689 Hodgkin Disease Doxorubicin 3.1118501091 15147373 17606976
MESH:D019584 Hot Flashes Estradiol 3.3817088409
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1616899240
MESH:D006937 Hypercholesterolemia Dietary Fats 8.1321332399
MESH:D006937 Hypercholesterolemia resveratrol 8.1317188708
MESH:D006940 Hyperemia Hydrochloric Acid 5.2812646421
MESH:D006943 Hyperglycemia pirinixic acid 8.1920558911
MESH:D006943 Hyperglycemia Quercetin 8.1918262572 11834736
MESH:D006949 Hyperlipidemias Dietary Fats 8.1721332399
MESH:D006949 Hyperlipidemias resveratrol 8.1716873680
MESH:D006973 Hypertension Cyclosporine 4.8010903974
MESH:D006973 Hypertension Quercetin 4.8018356687
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 10.2115338365
MESH:D006975 Hypertension, Portal Hydrochloric Acid 10.2116984587
MESH:D006976 Hypertension, Pulmonary Hydrochloric Acid 4.1919262391
MESH:D006980 Hyperthyroidism Methimazole 5.2714678291
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.9817488730
MESH:D007021 Hypospadias Ethinyl Estradiol 3.4516945680 16569931
MESH:D007022 Hypotension Hydrochloric Acid 4.4211574821
MESH:D007037 Hypothyroidism Methimazole 10.7518031379
MESH:D007037 Hypothyroidism Propylthiouracil 10.7518031379 8137927
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 10.2915869954
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 10.2917600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1212013081
MESH:D007248 Infertility, Male decitabine 5.9017581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 5.9017937319
MESH:D007249 Inflammation Dietary Fats 13.8020412841
MESH:D007249 Inflammation Diethylnitrosamine 13.8018785209
MESH:D007249 Inflammation Hydrochloric Acid 13.8011574821
MESH:D007249 Inflammation Progesterone 13.8015869954
MESH:D007249 Inflammation resveratrol 13.8016366677
MESH:D007251 Influenza, Human Quercetin 9.9516624496
MESH:D007251 Influenza, Human resveratrol 9.9516624496
MESH:D007333 Insulin Resistance Dietary Fats 10.8911836018 18457598
MESH:D007333 Insulin Resistance Estradiol 10.8916627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 10.8916306350
MESH:D007410 Intestinal Diseases Hydrochloric Acid 4.6111574821
MESH:D007627 Keloid Quercetin 4.6017086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0715604871
MESH:D007674 Kidney Diseases Cyclosporine 12.698314463 10903974 18776723
MESH:D007674 Kidney Diseases Doxorubicin 12.6915699352 15369732 16775033
MESH:D007674 Kidney Diseases Estradiol 12.6915618244
MESH:D007674 Kidney Diseases Quercetin 12.6916962696
MESH:D007676 Kidney Failure, Chronic Doxorubicin 9.0316707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 9.0316518626
MESH:D007680 Kidney Neoplasms Cyclosporine 10.7012371664
MESH:D007680 Kidney Neoplasms Estradiol 10.7015610895
MESH:D007680 Kidney Neoplasms Fluorouracil 10.7016985049
MESH:D007818 Laryngeal Diseases Hydrochloric Acid 5.9916498863
MESH:D007826 Laryngismus Hydrochloric Acid 5.9911510729
MESH:D007938 Leukemia arsenic trioxide 9.4615070760
MESH:D007938 Leukemia decitabine 9.4618980019 19235587
MESH:D007938 Leukemia Quercetin 9.4617468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.7816085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.4717077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.9416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 8.5019077051
MESH:D007951 Leukemia, Myeloid decitabine 8.5019117987 17236224 18454857
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.7419850784 16467208 20471514 16968895 17050201
MESH:D015470 Leukemia, Myeloid, Acute decitabine 3.7418460780 19387464 19010910 18704418 17679729 18206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.0918055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 6.9816112521 17869043 16891316 15622746 19035177 12018890 15213294 16966277 17107899 11161223 9834237 19225113 16330433 17649720 19642359 12679006 16823087 15748426 19075265 17217047 12712474 16331271 11468182 15336539 17712046
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 6.9816087638
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.0016882451
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 18.5517174718 16943688 17334410 17157831 16221502 11408273 11903743 16239168 21278145
MESH:D008103 Liver Cirrhosis Dietary Fats 18.5518296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 18.5518522880 18407596 19638242 20032147 18665156
MESH:D008103 Liver Cirrhosis Hydrochloric Acid 18.5516984587
MESH:D008103 Liver Cirrhosis Phenobarbital 18.5521047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 6.1817481882 18481824 17869086 12667390 18472094 11481614 16136751 17525996 12649538 17565644 16015684 15959796 15730626 15650968 18395914 12389079 12666154 14620537 17823541 12445418 18251166 12958196 18210741 12632512 14716496 18429990 18339082 18156304 15338365 20821823 16248980 17976157 15123356 17698563 18412020 16097048 17922224 16011737 17805973 15370692 16638106 14724832 14748882 12445421 15362042 16192424 18472332 12586293 12898905 15925388 12632514 15052691 17761835 17721639 17708605 17900296 18187930 10355542 17557913 15057751 18277467 18420326 15818738 12609069 15931870 13678700 18376398 18279442 17766677 15996030 15673190 18006644 12546737 16033810 17714472 18705752 14716833 17631135 18317297 16027843 16116963 18205269 15893842 15876570 17944888 18166357 18418968 18395095 18263696 12741479 14512876 18054572 17640975
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 6.1816439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.1814716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.1815474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 6.1812741479
MESH:D008107 Liver Diseases Carbon Tetrachloride 5.9216964402 16246199 15830285 17285989 15720792
MESH:D008107 Liver Diseases Diethylnitrosamine 5.9217034775
MESH:D008107 Liver Diseases Phenobarbital 5.9219363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8015123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.3716899240 14706259
MESH:D008113 Liver Neoplasms arsenic trioxide 23.3414682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 23.3419294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 23.3420501860 19254457 21047994 19426721 19255062 18648771 20118626 20101389 19850985 18977376 19996281 21167192 20434301 19499222 16942905 19294768 19256749 21278145 2422723 19690152 19833225 18754104 20405173 21071580 20452335 15175105 15885732 18644402 19090486 19642983 2862719 12771043 10737359 12112319 18978307 19638242 9163691 20137499 20583210 19551842 19073162 20492335 19427195 19812893
MESH:D008113 Liver Neoplasms Fluorouracil 23.3417045692 15113037 16603448 18383874
MESH:D008113 Liver Neoplasms Phenobarbital 23.3419812893 15975961 8742319 21047994 19482888 19073162
MESH:D008113 Liver Neoplasms pirinixic acid 23.3415890375 20007298 16377806
MESH:D008113 Liver Neoplasms Quercetin 23.3418980244
MESH:D008113 Liver Neoplasms resveratrol 23.3419321006 19812893 19073162 20405173
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 29.2320377131
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 29.2318544905
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 29.2315583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 29.2319539802 3124819 16267830 18544905 19009564 2563599 16842330 18079962 18308698 19004024 17174075 19126423 18775883 19519916 18253720 17942915 18093689 21159647 17854601 18282651 9362446 18164116
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 29.2317085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 29.23598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 29.231399818 18308698 17172636 2563599 6150874
MESH:D008114 Liver Neoplasms, Experimental Quercetin 29.2319519916
MESH:D008133 Long QT Syndrome arsenic trioxide 3.0715213294
MESH:D008171 Lung Diseases Ascorbic Acid 7.3116863852
MESH:D008171 Lung Diseases Hydrochloric Acid 7.3116784557
MESH:D055370 Lung Injury Hydrochloric Acid 8.5715044056 18497604 16129981 17627322 18573544 15090967 18339021 20597076 19644408 21311175 21114838 11395602 19262391 15607125
MESH:D055370 Lung Injury Oxygen 8.5718339021
MESH:D008175 Lung Neoplasms arsenic trioxide 9.8919825857 11798837
MESH:D008175 Lung Neoplasms Ascorbic Acid 9.8916401635
MESH:D008175 Lung Neoplasms Diethylnitrosamine 9.8920512841 20970405 6695378 21163286
MESH:D008175 Lung Neoplasms Doxorubicin 9.8917418594 6189445
MESH:D008175 Lung Neoplasms Fluorouracil 9.8915246190
MESH:D008175 Lung Neoplasms Methylcholanthrene 9.8916337739 17909032 20970405 11893704 7750092 6695378 9230183 20512841 16271038 21163286 15390079 10545420 1399818
MESH:D008175 Lung Neoplasms Quercetin 9.8916280456
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.4215086387
MESH:D008223 Lymphoma decitabine 6.8519470736
MESH:D008223 Lymphoma Doxorubicin 6.8516098063
MESH:D016393 Lymphoma, B-Cell resveratrol 3.9617088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 7.8917654614
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 7.8914749477
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.2115621674
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.8815688416
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 16.3212807724
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 16.3215458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 16.3211408345 17203775 11807958 16891317
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 16.3217203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 16.3211606380 8985016
MESH:D020149 Manganese Poisoning Estradiol 11.7619453300
MESH:D020149 Manganese Poisoning Manganese 11.7616551646 16568477 19453300
MESH:D008545 Melanoma decitabine 4.8016505122 17785578
MESH:D008545 Melanoma Doxorubicin 4.8016827129
MESH:D008545 Melanoma resveratrol 4.8017992120
MESH:D008654 Mesothelioma Doxorubicin 2.9117638057
MESH:D008659 Metabolic Diseases resveratrol 4.0517112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4116801185
MESH:D053842 Microsatellite Instability Methylnitronitrosoguanidine 5.5217671175
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.1715792986
MESH:D009062 Mouth Neoplasms Fluorouracil 3.3516757204 18986760
MESH:D009069 Movement Disorders Manganese 4.6716551646
MESH:D052016 Mucositis Doxorubicin 11.1917415656
MESH:D052016 Mucositis irinotecan 11.1917159606
MESH:D009101 Multiple Myeloma arsenic trioxide 10.6611468182 14977855 19549372 19417148 15949261
MESH:D009101 Multiple Myeloma decitabine 10.6618172295
MESH:D009101 Multiple Myeloma resveratrol 10.6617935668 16267019 14749477 16490592 17164350 17049120
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.5017962980
MESH:D009135 Muscular Diseases pirinixic acid 3.1516239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.3018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.7916882451 16105982
MESH:D009190 Myelodysplastic Syndromes decitabine 6.7919157545 18608210 19010910 16882708
MESH:D009203 Myocardial Infarction Doxorubicin 16.2019429709 15857846
MESH:D009203 Myocardial Infarction Hydrochloric Acid 16.2018534312
MESH:D009203 Myocardial Infarction pirinixic acid 16.2019151258
MESH:D009203 Myocardial Infarction Quercetin 16.2019595682
MESH:D009203 Myocardial Infarction resveratrol 16.2017015251 17188708 16456233 16525036 17125593 16317513
MESH:D017202 Myocardial Ischemia resveratrol 3.7217125593 17015251
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.5716810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.5716411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 12.5719207477
MESH:D009205 Myocarditis resveratrol 4.3917322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.1117484760
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.6116624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.703581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 8.7018259882
MESH:D009362 Neoplasm Metastasis irinotecan 8.7018259882
MESH:D009369 Neoplasms decitabine 10.3319470736 19116145 17925555
MESH:D009369 Neoplasms Fluorouracil 10.3318239605 18600527 16928823
MESH:D009369 Neoplasms pirinixic acid 10.3317405874
MESH:D009369 Neoplasms Quercetin 10.3315185748
MESH:D009374 Neoplasms, Experimental resveratrol 3.658985016
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3717289903
MESH:D009401 Nephrosis Doxorubicin 4.4116636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.2718481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.2716889571 15640375
MESH:D009410 Nerve Degeneration Manganese 7.9216551646
MESH:D009410 Nerve Degeneration Rotenone 7.9215790535 17356569 18619942
MESH:D009421 Nervous System Malformations Estradiol 3.3016427766 11399458
MESH:D009436 Neural Tube Defects arsenic trioxide 2.8810525206
MESH:D009447 Neuroblastoma Doxorubicin 6.5115555623
MESH:D009447 Neuroblastoma irinotecan 6.518761367
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.5420387270
MESH:D019636 Neurodegenerative Diseases resveratrol 7.5417652729
MESH:D017599 Neuroectodermal Tumors irinotecan 4.368761367
MESH:D020078 Neurogenic Inflammation Quercetin 9.5717929310
MESH:D020078 Neurogenic Inflammation resveratrol 9.5717929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.7420387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.1916436463
MESH:D009765 Obesity Ascorbic Acid 6.8917217161
MESH:D009765 Obesity Dietary Fats 6.8917217161 20132043 21332399 20518802 11836018 18457598 18674790 16723640 19632207
MESH:D009765 Obesity pirinixic acid 6.8920558911
MESH:D009784 Occupational Diseases Hydrochloric Acid 4.4512378975
MESH:D010018 Osteomalacia Phenobarbital 4.0017016548
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 9.0819495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 9.0817513867
MESH:D012516 Osteosarcoma Doxorubicin 3.8215930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 13.6419769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms decitabine 13.6419331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 13.6419401270
MESH:D010051 Ovarian Neoplasms Progesterone 13.6417393432 16525653
MESH:D010051 Ovarian Neoplasms Quercetin 13.6419005980
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 18.6615580305
MESH:D010190 Pancreatic Neoplasms decitabine 18.6619294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 18.6616540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 18.6615113037 16929163 19003803 16500647
MESH:D010190 Pancreatic Neoplasms Phenobarbital 18.6616965848
MESH:D010190 Pancreatic Neoplasms Quercetin 18.6616965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3511578682
MESH:D010212 Papilloma Hydrogen Peroxide 3.7312065085
MESH:D010235 Paraganglioma arsenic trioxide 3.8219927285
MESH:D010300 Parkinson Disease Manganese 5.3011181820
MESH:D010300 Parkinson Disease Rotenone 5.3019114014 16412576 15451049 16140633 11445065 18191903 19232380 18619942 11535288
MESH:D020734 Parkinsonian Disorders Manganese 8.4516140633
MESH:D020734 Parkinsonian Disorders Rotenone 8.4515574749 18197244 15927086 15795934
MESH:D010787 Photosensitivity Disorders 4-hydroxy-2-nonenal 5.1311550810
MESH:D003557 Phyllodes Tumor Doxorubicin 4.7817983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.7817638057
MESH:D011015 Pneumonia, Aspiration Hydrochloric Acid 5.0015607125 18573544 18497604 15970105
MESH:D011230 Precancerous Conditions Cyclosporine 19.3512371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 19.352563599
MESH:D011230 Precancerous Conditions Phenobarbital 19.352563599
MESH:D011230 Precancerous Conditions Quercetin 19.3519056647
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 3.8116679765
MESH:D055728 Primary Myelofibrosis decitabine 4.3717616702
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5620887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0419131511
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.0418437689 16868541 16729912 15749863 15897917 16888761
MESH:D011471 Prostatic Neoplasms equol 2.0416898868 16925846
MESH:D011471 Prostatic Neoplasms Estradiol 2.0416740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.0418626508 19082440
MESH:D011471 Prostatic Neoplasms Quercetin 2.0417292933 14715546
MESH:D011471 Prostatic Neoplasms resveratrol 2.0415767336 17675339 16731767 17804756 17718901 17636462
MESH:D011537 Pruritus Ethinyl Estradiol 2.9515861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 4.1212752131
MESH:D011565 Psoriasis Cyclosporine 2.1016882103
MESH:D001261 Pulmonary Atelectasis Hydrochloric Acid 5.6420597076
MESH:D011654 Pulmonary Edema Hydrochloric Acid 4.8415090967
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 4.9614606601
MESH:D012004 Rectal Neoplasms Fluorouracil 3.7015538739 18722050 16160472 18286688
MESH:D051437 Renal Insufficiency Doxorubicin 3.8617922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.2116325855
MESH:D015427 Reperfusion Injury pirinixic acid 5.9519058328
MESH:D015427 Reperfusion Injury resveratrol 5.9517058453 16314181 16317513 17520802 15827377
MESH:D012128 Respiratory Distress Syndrome, Adult Hydrochloric Acid 8.6316129981 16784557 18339021 17627322 18549715
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 8.6317627322 18339021
MESH:D012133 Respiratory Paralysis Hydrochloric Acid 5.9911510729
MESH:D012140 Respiratory Tract Diseases Hydrochloric Acid 4.7920516732
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 3.2016849425
MESH:D012208 Rhabdomyosarcoma decitabine 4.0619155313
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7218045962
MESH:D012509 Sarcoma Doxorubicin 3.6716767912 15675481 15625365 17710206 18313854 17203757
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 9.1216646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 9.1214601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.4217846226
MESH:D012554 Schistosomiasis japonica Quercetin 5.1716862918
MESH:D012640 Seizures Phenobarbital 2.453137016 4039156 11442880 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.456407741
MESH:D012871 Skin Diseases Ascorbic Acid 3.1118709164
MESH:D012878 Skin Neoplasms Doxorubicin 12.1615692506
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 12.1612065085
MESH:D012878 Skin Neoplasms resveratrol 12.168985016 15837718
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 12.168532709
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.2117203757 16767912 15625365
MESH:D013088 Spermatocele Ethinyl Estradiol 3.5716709447
MESH:D013119 Spinal Cord Injuries Progesterone 3.9116503802 15862959
MESH:D013274 Stomach Neoplasms arsenic trioxide 5.9517007042
MESH:D013274 Stomach Neoplasms decitabine 5.9519037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 5.9518456281
MESH:D013274 Stomach Neoplasms Fluorouracil 5.9517172411 16424979 18567086 18396642 19015929 17498489 17522103 16951190 15786421 19084572
MESH:D013274 Stomach Neoplasms irinotecan 5.9515723263
MESH:D013276 Stomach Ulcer Ascorbic Acid 6.8818726076
MESH:D013276 Stomach Ulcer Hydrochloric Acid 6.8817189318 15309881 16755016
MESH:D020521 Stroke Ascorbic Acid 4.0016403987 16517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.1616321402
MESH:D013398 Sudden Infant Death Oxygen 5.1812563064
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8515669648
MESH:D013964 Thyroid Neoplasms arsenic trioxide 24.4319014326
MESH:D013964 Thyroid Neoplasms decitabine 24.4317967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 24.437505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 24.4316010429 17909728
MESH:D013964 Thyroid Neoplasms Phenobarbital 24.431399818
MESH:D013964 Thyroid Neoplasms Propylthiouracil 24.4315710170
MESH:D013978 Tibial Fractures Estradiol 4.3119048282
MESH:D014062 Tongue Neoplasms Fluorouracil 8.9316280240
MESH:D014062 Tongue Neoplasms resveratrol 8.9316227395
MESH:D016171 Torsades de Pointes arsenic trioxide 3.5915213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 10.7211780464 20435036 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms decitabine 10.7219087683 17616700
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 10.7217653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 10.7216720314
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 8.5516803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 8.5517473185
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.3414692618
MESH:D014594 Uterine Neoplasms resveratrol 8.3417044934
MESH:D014604 Uveal Neoplasms decitabine 4.5417785578
MESH:D014605 Uveitis Cyclosporine 3.611336536
MESH:D014689 Venous Insufficiency coumarin 5.4012708602
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2115869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 9.1516364871 17334414 17638931 17678736
MESH:D018487 Ventricular Dysfunction, Left resveratrol 9.1517488730
MESH:D015430 Weight Gain Dietary Fats 3.4316723640
MESH:D014985 Xerophthalmia Cyclosporine 4.0717120751
Pathway ID Pathway Name
KEGG:04110 Cell cycle
REACT:1538 Cell Cycle Checkpoints
REACT:152 Cell Cycle, Mitotic
KEGG:03030 DNA replication
REACT:383 DNA Replication
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA30694
    • No data
    Releated disease ID Related disease Name
    PA445742Stomach Neoplasms
    Releated drug ID Related drug Name
    PA449957ibuprofen
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved