AutismKB 2.0

Annotation Detail for MCM7


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MCM7 ( CDC47,MCM2,P1.1-MCM3,P1CDC47,P85MCM,PNAS146 )
Gene Full Name: minichromosome maintenance complex component 7
Band: 7q22.1
Quick LinksEntrez ID:4176; OMIM: 600592; Uniprot ID:MCM7_HUMAN; ENSEMBL ID: ENSG00000166508; HGNC ID: 6950
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa03030DNA replication
hsa04110Cell cycle
Pathway IDPathway Name
Cell Cycle, Mitotic
DNA Replication
Cell Cycle Checkpoints
No data
No data
Pathway IDPathway Name
500964Removal of licensing factors from origins
500932Switching of origins to a post-replicative state
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of MCM7 mRNAaffects expression 21346803
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of MCM7 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of MCM7 mRNAaffects expression 17562736
C006632 arsenic trioxide arsenic trioxide results in increased expression of MCM7 proteinincreases expression 19364129
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of MCM7 mRNAdecreases expression 20064835
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of MCM7 proteinincreases expression 20097212
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MCM7 mRNAdecreases expression 20382639
C006780 bisphenol A bisphenol A results in increased expression of MCM7 mRNAincreases expression 16474171
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of MCM7 mRNAdecreases expression 15336504
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of MCM7 mRNAaffects expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of MCM7 mRNAincreases expression 19887370
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of MCM7 proteinincreases expression 19887370
D003345 Corticosterone Corticosterone results in decreased expression of MCM7 mRNAdecreases expression 15755911
C408982 CPG-oligonucleotide CPG-oligonucleotide results in increased expression of MCM7 proteinincreases expression 17727805
D003474 Curcumin Curcumin results in decreased expression of MCM7 mRNAdecreases expression 17198877
D016572 Cyclosporine Cyclosporine results in decreased expression of MCM7 mRNAdecreases expression 20106945
C014347 decitabine decitabine affects the methylation of MCM7 geneaffects methylation 17630775
D004052 Diethylnitrosamine AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of MCM7 mRNA]decreases expression|decreases reaction 19996281
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of MCM7 mRNAdecreases expression 19996281
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of MCM7 mRNAincreases expression 17854601
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of MCM7 proteinincreases expression 19887370
17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MCM7 mRNA]decreases reaction|increases expression 17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MCM7 protein]decreases reaction|increases expression 17854601
19887370
D004958 Estradiol Estradiol results in increased expression of MCM7 mRNAincreases expression 16474171
D004958 Estradiol Estradiol inhibits the reaction [Progesterone affects the localization of MCM7 protein]affects localization|decreases reaction 16966611
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of MCM7 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MCM7 mRNAaffects cotreatment|increases expression 17942748
D005472 Fluorouracil MCM7 protein affects the susceptibility to Fluorouracilaffects response to substance 15548681
D005472 Fluorouracil TP53 protein affects the reaction [Fluorouracil results in decreased expression of MCM7 mRNA]affects reaction|decreases expression 15016801
D019833 Genistein Genistein results in increased expression of MCM7 mRNAincreases expression 16474171
C008493 methylselenic acid methylselenic acid results in decreased expression of MCM7 mRNAdecreases expression 12517777
C093973 PD 98059 PD 98059 affects the expression of MCM7 mRNAaffects expression 14516785
C093973 PD 98059 PD 98059 affects the expression of MCM7 proteinaffects expression 14516785
C006253 pirinixic acid pirinixic acid results in increased expression of MCM7 mRNAincreases expression 17950772
18301758
17426115
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of MCM7 mRNA]increases expression|increases reaction 17950772
D011078 Polychlorinated Biphenyls Polychlorinated Biphenyls analog results in increased expression of MCM7 mRNAincreases expression 16474171
D011374 Progesterone Estradiol inhibits the reaction [Progesterone affects the localization of MCM7 protein]affects localization|decreases reaction 16966611
D011374 Progesterone Progesterone affects the localization of MCM7 proteinaffects localization 16966611
C487081 PXD101 PXD101 results in decreased expression of MCM7 mRNAdecreases expression 19606018
D012643 Selenium Selenium results in increased expression of MCM7 mRNAincreases expression 19244175
C017947 sodium arsenite sodium arsenite results in decreased expression of MCM7 mRNAdecreases expression 12760830
C017947 sodium arsenite sodium arsenite results in decreased expression of MCM7 mRNAdecreases expression 16014739
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MCM7 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of MCM7 mRNAdecreases expression 16611356
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of MCM7 mRNAincreases expression 15667827
C496197 trans-10,cis-12-conjugated linoleic acid trans-10,cis-12-conjugated linoleic acid results in decreased expression of MCM7 mRNAdecreases expression 17951470
D014212 Tretinoin Tretinoin results in decreased expression of MCM7 mRNAdecreases expression 16249480
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 7.557525203
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.5511752688 15322242 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6617505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.8618653653
MESH:D000230 Adenocarcinoma arsenic trioxide 16.1411798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 16.1420127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 16.1411473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 16.1414692618
MESH:D000230 Adenocarcinoma Fluorouracil 16.1417638652
MESH:D000230 Adenocarcinoma Genistein 16.1411473722
MESH:D000236 Adenoma Benzo(a)pyrene 6.096695378
MESH:D000236 Adenoma Diethylnitrosamine 6.096695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 15.6516434500 17620307 19052882 19061943 18056438 17162532
MESH:D018248 Adenoma, Liver Cell pirinixic acid 15.6516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 15.6516835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.4215276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.6217306315 16712894
MESH:D019973 Alcohol-Related Disorders Curcumin 4.8017887948
MESH:D000505 Alopecia Tretinoin 3.4015955085
MESH:D000544 Alzheimer Disease Curcumin 2.5615590663
MESH:D000740 Anemia Fluorouracil 7.8817963324 16511603 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.8811748828
MESH:D000799 Angioedema Acetaminophen 3.5610982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.8019183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1911256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.6415885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.6416412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 4.5016807698
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.5016292516
MESH:D001249 Asthma Tretinoin 2.2616456186
MESH:D050197 Atherosclerosis Curcumin 3.1618704882
MESH:D001321 Autistic Disorder Acetaminophen 1.4518445737
MESH:D001327 Autoimmune Diseases Curcumin 4.2219761891
MESH:D001471 Barrett Esophagus Tretinoin 4.1416935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 19.8916206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 19.8919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 19.8912125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 19.8916206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5915746008
MESH:D001862 Bone Resorption bisphenol A 3.6111985600
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.0517868700
MESH:D001930 Brain Injuries Progesterone 3.9815665606 15380490 15845082
MESH:D002545 Brain Ischemia Curcumin 4.0516770732
MESH:D001932 Brain Neoplasms Curcumin 3.7017596214
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 7.9620146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 7.9617123778
MESH:D001943 Breast Neoplasms Curcumin 7.9619250217 18593918 18462866 16243823
MESH:D001943 Breast Neoplasms decitabine 7.9618320071 19208741
MESH:D001943 Breast Neoplasms Diethylnitrosamine 7.9617474063
MESH:D001943 Breast Neoplasms Estradiol 7.9612948864 14630087 17289903 17018787 16675129 18497071 17261762 19861407
MESH:D001943 Breast Neoplasms Fluorouracil 7.9615136595 18608205 19217205 18357371 16110121 16557594 16595493
MESH:D001943 Breast Neoplasms Genistein 7.9616873071 16541309 17200150
MESH:D001943 Breast Neoplasms Progesterone 7.9617614352 15562024 16175315
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 7.9620435547
MESH:D001943 Breast Neoplasms Tretinoin 7.9616873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.3116813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.0711589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1816111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.5116124888 16227642 3786805 15700767 10355542 15673190 16011737 15721981 16050911 16192424 16097048 18705752
MESH:D002276 Carcinoid Tumor Fluorouracil 4.3816051944
MESH:D002277 Carcinoma Curcumin 12.7118593918
MESH:D002277 Carcinoma Fluorouracil 12.7117121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 12.7116835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.8716168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 21.9416705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 21.943084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 21.9415553829 14691202 11135700 16217749 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 21.9418788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 21.9419335982 18788625 3581430 19701751 16779866 16569478 18978308 20727157 11831363 20007298 16830150 20214788 20512989 17173139 16698587 16935385 19383236 16878318 18785209 19919837 16681979 17138121 20524982 19208518 18056438 17978847 16540662 18393292 17428255 19052882 17055752 18506893 10737359 16288022 19418558 18210153 20101231 3084413 16807293 17761372 20935162 20514400 18971187 16502159 17162532 19171122 19519916 10672840 19107877 19539802 18494052 21159647 20084675 16328049 18665156 19822196 19394651 18691550 20432363
MESH:D006528 Carcinoma, Hepatocellular Estradiol 21.9416924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 21.9417088986 16332177 16799960 17045692 18930000 17971768
MESH:D006528 Carcinoma, Hepatocellular Genistein 21.9416924424
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 21.9416507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 21.941917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.7117123778
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.8818414057
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.5919014326
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.8918695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.8812490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 16.9720419170
MESH:D002294 Carcinoma, Squamous Cell Curcumin 16.9718462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 16.9719215824
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 16.9716280240 16757204 17066447 18986760
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 16.9718572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 16.9716096774 16051514
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2118850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases Genistein 3.1116332659
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 11.4314694615
MESH:D002386 Cataract Acetaminophen 11.4310977129
MESH:D002386 Cataract Tretinoin 11.4317460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 19.0620889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 19.0612371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 19.0617174075 2727394 21159647 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 19.0618566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 19.0619524636 20056578
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.3116129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.5519052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.5516835633
MESH:D002779 Cholestasis Cyclosporine 12.1619486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.1616919318 11677210 16105132 17110522 17681005 17333356 15861022
MESH:D002779 Cholestasis pirinixic acid 12.1619176532
MESH:D002822 Choriocarcinoma Tretinoin 4.8716461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.3715668235 8697196 16354765 15340226 12621046
MESH:D002972 Cleft Palate Tretinoin 5.379407595
MESH:D003092 Colitis Curcumin 14.4616804969 16782535 18200517
MESH:D003092 Colitis Selenium 14.4617936198
MESH:D003092 Colitis Tretinoin 14.4617035595
MESH:D003103 Coloboma Curcumin 4.3018809619
MESH:D003110 Colonic Neoplasms Curcumin 7.8716340194 19359593
MESH:D003110 Colonic Neoplasms decitabine 7.8717616700
MESH:D003110 Colonic Neoplasms Fluorouracil 7.8716510598 17287894 15001691 18772588 17725105 17016597 17172411 16340194 17018589 17169374
MESH:D003110 Colonic Neoplasms Genistein 7.8717182828
MESH:D015179 Colorectal Neoplasms arsenic trioxide 4.6020501625
MESH:D015179 Colorectal Neoplasms decitabine 4.6018981723
MESH:D015179 Colorectal Neoplasms Fluorouracil 4.6018509181 17594712 16282729 18448328 16303861 17094418 17454858 15289873 18383874 18949393 15148649 17255274 18802399 18288408 17695437 17016601 14970324 16391804 16524972 20501625 17401013 16331619
MESH:D015179 Colorectal Neoplasms Polychlorinated Biphenyls 4.6015531428
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 8.4115095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.4114669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 4.6218497527
MESH:D023903 Coronary Restenosis arsenic trioxide 3.9212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.5710525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.5710048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.579664655 17551590 14991402 16925845 9211117 10589399 9125849 9142499 8800419 9224671
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.7418551238
MESH:D007644 Darier Disease Fluorouracil 4.5116733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.8415213294
MESH:D003704 Dementia Polychlorinated Biphenyls 4.4516140633
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3018249437
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 9.6518403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 9.6520387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 9.6516647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 9.6517107852
MESH:D003928 Diabetic Nephropathies Curcumin 8.2618204486
MESH:D003928 Diabetic Nephropathies Estradiol 8.2619279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.2217187935
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 17.3321346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 17.3321346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 17.3311834606 16177239 12392966 17522070 16393943 14725611 10663392 11421492 11529661 17906064 19164858 18071297 18713872 19085960 15619225 15968718 11743745 11461765 11739529 16781746 16485898 19416960 12594235 11287661 19420014 19739265 10774834 12705907 12958197 10915739 19923254 16081117 12540782 14986274 14550746 16109766 2444490 17562736 19370779 12153990 16227642
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 17.3316227642 3786805 16177239 15027814 15968718 6884620 21278145 10915739 11566570 7179309 19085960 6623471 17522070 7120509 4309450 3732212 7440962 15998439 19336974 10092053 2869522 9327722
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 17.3319107877
MESH:D056486 Drug-Induced Liver Injury Selenium 17.3315131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 17.3320420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.8119426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5611462148
MESH:D004381 Duodenal Ulcer Curcumin 3.7817351913
MESH:D004487 Edema pirinixic acid 5.7212083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.7211000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.0018230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 11.0018230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.1512538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 8.1517692515
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.8319294695
MESH:D004714 Endometrial Hyperplasia Genistein 4.3116402032
MESH:D016889 Endometrial Neoplasms Estradiol 11.4219148513 18566989 11473722
MESH:D016889 Endometrial Neoplasms Genistein 11.4211473722
MESH:D016889 Endometrial Neoplasms Tretinoin 11.4216569247
MESH:D004715 Endometriosis Progesterone 8.1316134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.1310568697 9294722
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.8316302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 9.7620426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 9.7612903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 9.7616530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 9.7616337965 17638652 15173087 16785472 16481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.1511564622
MESH:D005124 Eye Abnormalities Tretinoin 8.159664655 16938888
MESH:D005234 Fatty Liver arsenic trioxide 33.1315073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 33.1312631006 61145 12795759 16239168 15959796 17595544 16045604 19224547
MESH:D005234 Fatty Liver Curcumin 33.1319297423
MESH:D005234 Fatty Liver Cyclosporine 33.1319224547
MESH:D005234 Fatty Liver Diethylnitrosamine 33.1321071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 33.1315345470
MESH:D005234 Fatty Liver pirinixic acid 33.1319236843 20131406
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1811858732
MESH:D005355 Fibrosis Carbon Tetrachloride 24.8218705752
MESH:D005355 Fibrosis Curcumin 24.8218705752
MESH:D005355 Fibrosis Cyclosporine 24.8212168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 24.8220067830
MESH:D005355 Fibrosis Tretinoin 24.8217994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.0016904648
MESH:D005756 Gastritis Acetaminophen 3.3916983495
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.4218462866
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.4016452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.948708960
MESH:D005909 Glioblastoma Curcumin 10.9017596214
MESH:D005909 Glioblastoma Genistein 10.9016598420
MESH:D005909 Glioblastoma Tretinoin 10.9017312396
MESH:D005910 Glioma Fluorouracil 2.7616145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3110696789
MESH:D006258 Head and Neck Neoplasms Curcumin 16.9418829502 18462866
MESH:D006258 Head and Neck Neoplasms decitabine 16.9419215824
MESH:D006258 Head and Neck Neoplasms Fluorouracil 16.9415162350 15102660 18337622
MESH:D006258 Head and Neck Neoplasms Tretinoin 16.9416096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.8716084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.2320471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.2311294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 10.239664655 14991402
MESH:D006333 Heart Failure pirinixic acid 6.3820558911
MESH:D006333 Heart Failure Selenium 6.3817162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.1415720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0911000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.3319900420 19110552
MESH:D006529 Hepatomegaly pirinixic acid 7.3516221962 19176532 19772884 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.3515340226 16120746 12621046
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.7717701891
MESH:D006558 Herpes Genitalis Estradiol 4.7515709030
MESH:D006689 Hodgkin Disease sodium arsenite 2.9312676792
MESH:D019584 Hot Flashes Estradiol 3.4717088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.768697196 16959395 15340226 16354765 18606429
MESH:D006930 Hyperalgesia Acetaminophen 6.9016870215
MESH:D006930 Hyperalgesia Tretinoin 6.9016870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.2516899240
MESH:D006937 Hypercholesterolemia Curcumin 3.8018704882
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2916778211
MESH:D006943 Hyperglycemia pirinixic acid 2.9420558911
MESH:D006973 Hypertension Cyclosporine 4.5810903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.5818670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.8115338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.5416569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.1315869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2012013081
MESH:D007248 Infertility, Male decitabine 10.1617581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 10.1617937319
MESH:D007248 Infertility, Male sodium arsenite 10.1615346721 12646999
MESH:D007249 Inflammation Curcumin 10.7718403477 17151092 16956363
MESH:D007249 Inflammation Diethylnitrosamine 10.7718785209
MESH:D007249 Inflammation Progesterone 10.7715869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 10.7712200463 12878042
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.1018200517 18596194
MESH:D007251 Influenza, Human Selenium 3.9116624496
MESH:D007333 Insulin Resistance bisphenol A 11.2716393666
MESH:D007333 Insulin Resistance Estradiol 11.2716393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 11.2716306350
MESH:D007410 Intestinal Diseases Tretinoin 3.4917994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.9810783313
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.1016580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.1015992940 17551590
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.1615604871
MESH:D007674 Kidney Diseases Acetaminophen 13.0912587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 13.0918776723 10903974 8314463
MESH:D007674 Kidney Diseases Estradiol 13.0915618244
MESH:D007674 Kidney Diseases sodium arsenite 13.0920008137
MESH:D007676 Kidney Failure, Chronic Selenium 3.6416518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 15.9116705839
MESH:D007680 Kidney Neoplasms Cyclosporine 15.9112371664
MESH:D007680 Kidney Neoplasms Estradiol 15.9115610895
MESH:D007680 Kidney Neoplasms Fluorouracil 15.9116985049
MESH:D007889 Leiomyoma Curcumin 4.3118555241
MESH:D007938 Leukemia arsenic trioxide 18.2115070760
MESH:D007938 Leukemia Curcumin 18.2118462866
MESH:D007938 Leukemia decitabine 18.2118980019 19235587
MESH:D007938 Leukemia Genistein 18.2117468513 18980019
MESH:D007938 Leukemia Tretinoin 18.2117143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 8.9317077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 8.9316106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 10.7916972261
MESH:D007948 Leukemia, Monocytic, Acute PD 98059 10.7916972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.2214633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 14.5519077051
MESH:D007951 Leukemia, Myeloid decitabine 14.5517236224 19117987 18454857
MESH:D007951 Leukemia, Myeloid Tretinoin 14.5516932348 16482212 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.8216467208 20471514 17050201 16968895 19850784
MESH:D015470 Leukemia, Myeloid, Acute decitabine 5.8219010910 19387464 18460780 18704418 18206229 17679729
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 5.8217596541 16294345 19850784
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.1818055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.0316891316 19035177 15213294 16331271 19075265 15748426 12679006 11468182 16823087 11161223 12712474 16112521 17712046 19225113 19642359 15336539 17107899 17869043 17649720 17217047 9834237 15622746 12018890 16330433 16966277
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.0319035177 16766008 19075265 16331271 17712046 12679006 17361223 9834237 16935935 17301526 17649720 16140955 17107899 17506722 16823087 19029980 16788101 17217047 19225113 17368321 17339181 15748426 16891316 17294898 19642359
MESH:D015458 Leukemia, T-Cell arsenic trioxide 10.8316882451
MESH:D015458 Leukemia, T-Cell Curcumin 10.8316106398
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.119224671
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.1021278145 11903743 11408273 17334410 16943688 16221502 16239168 17174718 17157831
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.1018522880 18407596 18665156 19638242 20032147
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 10.3418472332 15650968 16136751 15876570 17761835 15893842 17900296 15996030 12666154 13678700 18395914 12958196 15370692 14724832 14512876 12667390 17823541 18156304 15338365 17721639 16033810 12445421 17708605 18263696 17714472 17640975 17869086 15959796 17481882 12586293 18210741 12546737 16248980 18429990 12445418 17557913 18412020 12898905 18006644 11481614 18376398 18279442 14748882 15052691 17805973 16011737 16638106 20821823 18277467 15123356 12609069 18317297 12389079 16027843 15730626 17766677 18420326 16116963 17922224 15362042 16097048 18187930 18251166 17565644 16015684 18339082 15818738 12632514 15931870 12741479 14620537 10355542 14716496 18418968 15673190 17631135 17698563 17525996 12649538 16192424 15925388 12632512 18472094 17976157 18054572 18205269 18395095 18705752 14716833 15057751 18481824 17944888 18166357
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 10.3418006644 18705752 17355460
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 10.3414659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 10.3417823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 10.3415474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 10.3412878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 10.3416248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 8.7519784758 16611625 19014921 11587558 19460945 12587719 16610002 12969438
MESH:D008107 Liver Diseases Carbon Tetrachloride 8.7517285989 16246199 15720792 15830285 16964402
MESH:D008107 Liver Diseases Curcumin 8.7516956363
MESH:D008107 Liver Diseases Diethylnitrosamine 8.7517034775
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8915123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.6116871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.6116899240 14706259
MESH:D008113 Liver Neoplasms arsenic trioxide 24.0514682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 24.0520195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 24.0519294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 24.0519833225 20101389 2862719 18977376 20583210 19812893 19850985 19638242 20118626 19427195 2422723 20137499 19255062 19690152 20501860 20452335 19256749 16942905 19090486 21278145 19642983 19254457 21071580 18644402 20405173 18648771 20492335 19426721 10737359 12771043 21167192 18754104 9163691 19294768 15885732 12112319 20434301 19499222 18978307 15175105 19996281 21047994 19551842 19073162
MESH:D008113 Liver Neoplasms Fluorouracil 24.0515113037 17045692 16603448 18383874
MESH:D008113 Liver Neoplasms pirinixic acid 24.0520007298 15890375 16377806
MESH:D008113 Liver Neoplasms sodium arsenite 24.0516712894 15276417
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 24.0516984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 16.8120377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 16.8115583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 16.8116267830 9362446 18544905 17174075 18775883 18093689 19539802 18282651 18079962 19004024 19126423 19519916 19009564 18164116 3124819 21159647 17854601 18308698 2563599 18253720 17942915 16842330
MESH:D008114 Liver Neoplasms, Experimental Polychlorinated Biphenyls 16.811423854
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 16.8112151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.1415213294
MESH:D008171 Lung Diseases sodium arsenite 2.9919095001
MESH:D008175 Lung Neoplasms arsenic trioxide 10.1319825857 11798837
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 10.1318520028 20464547 17053015 6695378 20064080 18569708 20869020 20135361 18816296
MESH:D008175 Lung Neoplasms Curcumin 10.1319359593 18462866 16243823
MESH:D008175 Lung Neoplasms Diethylnitrosamine 10.136695378 20970405 21163286 20512841
MESH:D008175 Lung Neoplasms Fluorouracil 10.1315246190
MESH:D008175 Lung Neoplasms sodium arsenite 10.1315276417 17077188 16712894 17306315 19931552
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 10.1319555203 11884234
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.5115086387
MESH:D008223 Lymphoma Curcumin 7.1218462866
MESH:D008223 Lymphoma decitabine 7.1219470736
MESH:D016399 Lymphoma, T-Cell Curcumin 4.4216173963
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 16.9512807724
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 16.9516891317 11807958 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Genistein 16.9514578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 16.9517203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Selenium 16.9515318939
MESH:D020149 Manganese Poisoning Estradiol 4.2019453300
MESH:D008527 Medulloblastoma Tretinoin 2.6717453147
MESH:D008545 Melanoma Curcumin 6.8818462866 17885582
MESH:D008545 Melanoma decitabine 6.8817785578 16505122
MESH:D008545 Melanoma sodium arsenite 6.8819082730 16487513
MESH:D008545 Melanoma Tretinoin 6.8816752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2919513568
MESH:D008569 Memory Disorders Curcumin 3.8917263510
MESH:D008591 Meningomyelocele Tretinoin 4.1516940565
MESH:D008654 Mesothelioma Selenium 2.6815107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5016801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 7.8316381670
MESH:D009062 Mouth Neoplasms Fluorouracil 7.8316757204 18986760
MESH:D009101 Multiple Myeloma arsenic trioxide 11.0519417148 19549372 14977855 15949261 11468182
MESH:D009101 Multiple Myeloma Curcumin 11.0519372569
MESH:D009101 Multiple Myeloma decitabine 11.0518172295
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.6417962980
MESH:D009135 Muscular Diseases pirinixic acid 3.2316239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.3918349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 11.4216105982 16882451
MESH:D009190 Myelodysplastic Syndromes decitabine 11.4219010910 16882708 19157545 18608210
MESH:D009190 Myelodysplastic Syndromes Tretinoin 11.4217596541
MESH:D009203 Myocardial Infarction Genistein 5.2817141266
MESH:D009203 Myocardial Infarction pirinixic acid 5.2819151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8012213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.9516810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 12.9517141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.9516411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.5818551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 9.4416624393
MESH:D009361 Neoplasm Invasiveness Curcumin 9.4418495463
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.469029167 3581430
MESH:D009369 Neoplasms Benzo(a)pyrene 17.9811141357
MESH:D009369 Neoplasms decitabine 17.9819470736 19116145 17925555
MESH:D009369 Neoplasms Fluorouracil 17.9818239605 18600527 16928823
MESH:D009369 Neoplasms pirinixic acid 17.9817405874
MESH:D009369 Neoplasms sodium arsenite 17.9811559025
MESH:D009369 Neoplasms Tretinoin 17.9816946489 16594593
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.3920056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 4.2512497104
MESH:D009389 Neovascularization, Pathologic Estradiol 3.4517289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.1617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.0519348381 18481113
MESH:D009421 Nervous System Malformations bisphenol A 27.9016427766 11399458
MESH:D009421 Nervous System Malformations Estradiol 27.9011399458 16427766
MESH:D009421 Nervous System Malformations Genistein 27.9016427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 27.9014600291
MESH:D009421 Nervous System Malformations Tretinoin 27.909125849
MESH:D009423 Nervous System Neoplasms Curcumin 5.3518462866
MESH:D009436 Neural Tube Defects arsenic trioxide 11.1110525206
MESH:D009436 Neural Tube Defects sodium arsenite 11.1112854658
MESH:D009436 Neural Tube Defects Tretinoin 11.119142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.4318514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.4320387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.8320387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.2516436463
MESH:D009765 Obesity Curcumin 4.3619297423
MESH:D009765 Obesity pirinixic acid 4.3620558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.3312819281 16049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 8.3314694615
MESH:D010024 Osteoporosis Curcumin 6.7918719352
MESH:D010024 Osteoporosis Genistein 6.7919401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.8316169203
MESH:D010049 Ovarian Diseases bisphenol A 4.7111985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 25.5519769630 12452020 16624393
MESH:D010051 Ovarian Neoplasms Curcumin 25.5519020741 18462866
MESH:D010051 Ovarian Neoplasms decitabine 25.5519331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 25.5519401270
MESH:D010051 Ovarian Neoplasms Genistein 25.5519005980
MESH:D010051 Ovarian Neoplasms Progesterone 25.5517393432 16525653
MESH:D010051 Ovarian Neoplasms sodium arsenite 25.5517306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 25.5516936753
MESH:D010146 Pain Acetaminophen 5.8516870215
MESH:D010146 Pain Tretinoin 5.8516870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 19.1615580305
MESH:D010190 Pancreatic Neoplasms Curcumin 19.1619401701 17440100 19196508
MESH:D010190 Pancreatic Neoplasms decitabine 19.1619294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 19.1616540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 19.1619003803 16929163 16500647 15113037
MESH:D010190 Pancreatic Neoplasms Tretinoin 19.1615976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4311578682
MESH:D010235 Paraganglioma arsenic trioxide 3.9019927285
MESH:D010300 Parkinson Disease Polychlorinated Biphenyls 3.2916702228
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9612520081
MESH:D010954 Plasmacytoma Selenium 4.6015087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2918163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.1712371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.172563599
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 8.5810548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.5811118676 11896295 11399792 11222880
MESH:D055728 Primary Myelofibrosis decitabine 4.4517616702
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.7220887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.7220887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.4319131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.4317292933
MESH:D011471 Prostatic Neoplasms bisphenol A 3.4316740699
MESH:D011471 Prostatic Neoplasms Curcumin 3.4318769126 12497104 11398177 15129424 18156803 10851300 18226269
MESH:D011471 Prostatic Neoplasms Estradiol 3.4316740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.4319082440 18626508
MESH:D011471 Prostatic Neoplasms Genistein 3.4315378649 15256057 16925846
MESH:D011471 Prostatic Neoplasms methylselenic acid 3.4316205645
MESH:D011471 Prostatic Neoplasms Polychlorinated Biphenyls 3.4315721890
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.4316039940
MESH:D011507 Proteinuria Tretinoin 3.3516636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.0315861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.1316882103
MESH:D011625 Pterygium Tretinoin 4.5116723453
MESH:D011629 Puberty, Precocious bisphenol A 4.5110548101
MESH:D011656 Pulmonary Emphysema Curcumin 4.2819168576
MESH:D012004 Rectal Neoplasms Fluorouracil 3.7818722050 18286688 15538739 16160472
MESH:D015427 Reperfusion Injury pirinixic acid 2.2519058328
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.7718379247 10666014
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5718990726
MESH:D012208 Rhabdomyosarcoma decitabine 10.0919155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 10.0916116481 16283617
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7618045962
MESH:D012509 Sarcoma Curcumin 3.8818462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.6916646077
MESH:D012640 Seizures 2,4-dinitrotoluene 2.3518551238
MESH:D018805 Sepsis Curcumin 3.8518389075
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 16.5010029692 19755658
MESH:D012878 Skin Neoplasms sodium arsenite 16.5019524636 18572023
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 16.508532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 16.5016192470
MESH:D012878 Skin Neoplasms Tretinoin 16.5016467112
MESH:D013088 Spermatocele Ethinyl Estradiol 3.6616709447
MESH:D013119 Spinal Cord Injuries Progesterone 4.0016503802 15862959
MESH:D016135 Spinal Dysraphism sodium arsenite 3.5812854658
MESH:D013274 Stomach Neoplasms arsenic trioxide 7.9017007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 7.902093021 20155912
MESH:D013274 Stomach Neoplasms decitabine 7.9019037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 7.9018456281
MESH:D013274 Stomach Neoplasms Fluorouracil 7.9015786421 16424979 16951190 18396642 17172411 17522103 18567086 17498489 19015929 19084572
MESH:D013274 Stomach Neoplasms Tretinoin 7.9017261132
MESH:D013276 Stomach Ulcer Curcumin 3.2616631530 19188055
MESH:D019966 Substance-Related Disorders bisphenol A 3.7116045194 16684133
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9215669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6212697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 15.3919014326
MESH:D013964 Thyroid Neoplasms decitabine 15.3917967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 15.397505956
MESH:D013964 Thyroid Neoplasms Tretinoin 15.3917045167 16026305
MESH:D013978 Tibial Fractures Estradiol 4.4019048282
MESH:D014062 Tongue Neoplasms Fluorouracil 9.0316280240
MESH:D014062 Tongue Neoplasms Tretinoin 9.0316051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.6815213294
MESH:D014376 Tuberculosis Tretinoin 3.0616040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 18.4316049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 18.4312973940 20435036 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 18.4317053015
MESH:D001749 Urinary Bladder Neoplasms Curcumin 18.4318593936
MESH:D001749 Urinary Bladder Neoplasms decitabine 18.4319087683 17616700
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 18.4316452187 16712894 11723127 17306315
MESH:D014565 Urogenital Neoplasms Curcumin 4.9818462866
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.0410091137
MESH:D014581 Urticaria Acetaminophen 2.7210982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 14.4616803524
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 14.4611813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 14.4616129372
MESH:D014591 Uterine Diseases bisphenol A 4.7214652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.0314692618
MESH:D014604 Uveal Neoplasms decitabine 11.8817785578
MESH:D014604 Uveal Neoplasms Tretinoin 11.8816752155
MESH:D014605 Uveitis Cyclosporine 3.701336536
MESH:D014652 Vascular Diseases sodium arsenite 4.1417056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3112125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2914671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.7916761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9615886252
MESH:D009396 Wilms Tumor Tretinoin 3.7316287080
MESH:D014985 Xerophthalmia Cyclosporine 4.1617120751
Pathway ID Pathway Name
KEGG:04110 Cell cycle
REACT:1538 Cell Cycle Checkpoints
REACT:152 Cell Cycle, Mitotic
REACT:383 DNA Replication
KEGG:03030 DNA replication
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA30697
  • No data
    Releated disease ID Related disease Name
    PA445742Stomach Neoplasms
    Releated drug ID Related drug Name
    PA449957ibuprofen
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018