AutismKB 2.0

Annotation Detail for MDM2


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Basic Information Top
Gene Symbol:MDM2 ( HDMX,MGC5370,MGC71221,hdm2 )
Gene Full Name: Mdm2 p53 binding protein homolog (mouse)
Band: 12q15
Quick LinksEntrez ID:4193; OMIM: 164785; Uniprot ID:MDM2_HUMAN; ENSEMBL ID: ENSG00000135679; HGNC ID: 6973
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04144Endocytosis
hsa05219Bladder cancer
hsa04120Ubiquitin mediated proteolysis
hsa04110Cell cycle
hsa04115p53 signaling pathway
hsa05220Chronic myeloid leukemia
hsa05218Melanoma
hsa05214Glioma
hsa05215Prostate cancer
hsa05200Pathways in cancer
Pathway IDPathway Name
Synaptic Transmission
Signalling by NGF
Cell Cycle Checkpoints
Pathway IDPathway Name
200009ErbB4 signaling events
200097Sumoylation by RanBP2 regulates transcriptional repression
200175p53 pathway
200077Glucocorticoid receptor regulatory network
200166Aurora A signaling
200101Direct p53 effectors
200102Regulation of Androgen receptor activity
200191Regulation of retinoblastoma protein
Pathway IDPathway Name
P00060Ubiquitin proteasome pathway
P04398p53 pathway feedback loops 2
P00033Insulin/IGF pathway-protein kinase B signaling cascade
P00059p53 pathway
P04392P53 pathway feedback loops 1
Pathway IDPathway Name
500171Trafficking of AMPA receptors
500640AKT phosphorylates targets in the cytosol
500316Stabilization of p53
Related Diseases/Disorders Top
Desease IDDesease Name
Cancers
H00037Alveolar rhabdomyosarcoma
H00036Osteosarcoma
Cancers of the urinary system and male genital organs
H00028Choriocarcinoma
H00025Penile cancer
H00042Glioma
Cancers of soft tissues and bone
Cancers of the breast and female genital organs
Cancers of the nervous system
Desease IDDesease Name
1751Schistosomiasis
1781Rheumatoid arthritis
1799Epilepsy
1850Herpes
1901Endometriosis
1934Cancer
1986Eating disorder
2100Hepatitis C
2118Adenovirus infection
2125Bladder cancer
2233Cirrhosis
Desease Name
DNA Damage
colorectal cancer
liver cancer
Osteosarcoma
CANCER
Helicobacter Infections
stomach cancer
Lung Neoplasms
endometrial cancer
nasopharyngeal cancer
bladder cancer
Endometrial Neoplasms
breast cancer
pregnancy loss
Stomach Neoplasms
Leukemia, Lymphocytic, Chronic, B-Cell
lung cancer
Breast Neoplasms
REPRODUCTION
No data
Desease Name
Accelerated tumor formation, susceptibility to
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C028098 10-hydroxycamptothecin MDM2 protein affects the susceptibility to 10-hydroxycamptothecinaffects response to substance 13130078
C112765 17-(allylamino)-17-demethoxygeldanamycin 17-(allylamino)-17-demethoxygeldanamycin results in increased degradation of MDM2 proteinincreases degradation 17157164
C095284 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one results in increased expression of MDM2 proteinincreases expression 16288207
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of MDM2 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of MDM2 mRNAaffects expression 21346803
C049584 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MDM2 proteinincreases expression 15635149
C019499 2-nitrofluorene 2-nitrofluorene results in increased expression of MDM2 mRNAincreases expression 15890375
14600272
C054649 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of MDM2 mRNAincreases expression 12734338
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of MDM2 mRNAincreases expression 16788091
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of MDM2 mRNAincreases expression 18648102
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MDM2 mRNAincreases expression 15890375
14600272
C471843 6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine 6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine results in decreased expression of MDM2 proteindecreases expression 15958644
D000082 Acetaminophen Acetaminophen affects the expression of MDM2 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen promotes the reaction [MDM2 protein binds to TP53 protein]affects binding|increases reaction 16330492
D000082 Acetaminophen Acetaminophen results in increased expression of MDM2 mRNAincreases expression 17202762
D000082 Acetaminophen Acetaminophen results in increased phosphorylation of MDM2 proteinincreases phosphorylation 16330492
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of MDM2 proteinaffects expression 20106945
D016604 Aflatoxin B1 Aflatoxin B1 results in increased expression of MDM2 mRNAincreases expression 15890375
14600272
C011512 alpha-naphthoflavone alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 mRNA]]decreases reaction|increases expression|increases reaction 19578757
C011512 alpha-naphthoflavone alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNA]decreases reaction|increases expression 19578757
C067527 aluminum maltolate aluminum maltolate results in increased expression of MDM2 mRNAincreases expression 15537749
D009762 o-Aminoazotoluene o-Aminoazotoluene results in increased expression of MDM2 mRNAincreases expression 15346788
D006710 Homocysteine Homocysteine results in decreased expression of MDM2 mRNAdecreases expression 17326132
D000643 Ammonium Chloride Ammonium Chloride results in increased expression of MDM2 mRNAincreases expression 12420312
D000643 Ammonium Chloride Ammonium Chloride results in increased expression of MDM2 proteinincreases expression 16483693
D000677 Amsacrine MDM2 promoter SNP results in decreased susceptibility to Amsacrinedecreases response to substance 17575151
C006632 arsenic trioxide arsenic trioxide results in decreased expression of MDM2 mRNAdecreases expression 20458559
C006632 arsenic trioxide arsenic trioxide results in increased expression of MDM2 mRNAincreases expression 17487067
C006632 arsenic trioxide pifithrin inhibits the reaction [arsenic trioxide results in increased expression of MDM2 mRNA]decreases reaction|increases expression 17487067
D001554 Benzene Benzene results in increased expression of MDM2 mRNAincreases expression 15935812
15342939
11896287
D001554 Benzene TRP53 protein affects the reaction [Benzene results in increased expression of MDM2 mRNA]affects reaction|increases expression 11896287
D001554 Benzene [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of MDM2 mRNAaffects cotreatment|increases expression 17905399
D001564 Benzo(a)pyrene Benzo(a)pyrene promotes the reaction [TP53 protein binds to MDM2 protein]affects binding|increases reaction 15625077
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of MDM2 mRNAincreases expression 18418871
20106945
D001564 Benzo(a)pyrene Simvastatin promotes the reaction [Benzo(a)pyrene promotes the reaction [TP53 protein binds to MDM2 protein]]affects binding|increases reaction 15625077
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of MDM2 mRNAincreases expression 19146932
18973830
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of MDM2 mRNAincreases expression 20382639
C072553 benzyloxycarbonylleucyl-leucyl-leucine aldehyde benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]]affects binding|increases reaction 17575151
D002101 Cacodylic Acid Cacodylic Acid results in increased expression of MDM2 mRNAincreases expression 17481689
D002166 Camptothecin Camptothecin results in increased expression of MDM2 proteinincreases expression 17555331
D002259 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MDM2 mRNAdecreases expression 16039398
D002699 Chlorambucil Chlorambucil results in increased expression of MDM2 mRNAincreases expression 17476690
D003474 Curcumin Curcumin results in decreased expression of MDM2 mRNAdecreases expression 17332326
D003474 Curcumin Curcumin results in decreased expression of MDM2 proteindecreases expression 17332326
D003474 Curcumin [Curcumin results in decreased expression of MDM2 protein] which results in decreased expression of CDKN1A mRNAdecreases expression 17332326
D016572 Cyclosporine Cyclosporine results in increased expression of MDM2 mRNAincreases expression 20106945
C014347 decitabine decitabine affects the expression of MDM2 mRNAaffects expression 17145863
D002945 Cisplatin Cisplatin results in increased expression of MDM2 proteinincreases expression 16797627
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of MDM2 mRNAincreases expression 17854601
19100860
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of MDM2 proteinincreases expression 18506893
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MDM2 mRNA]decreases reaction|increases expression 17854601
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of MDM2 proteinaffects cotreatment|affects expression|affects localization 11003613
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MDM2 mRNAaffects cotreatment|decreases expression 18544905
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of MDM2 mRNAincreases expression 15459018
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of MDM2 mRNAincreases expression 15545218
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of MDM2 mRNAincreases expression 15890375
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of MDM2 mRNAincreases expression 14600272
15890375
C067311 docetaxel docetaxel results in increased expression of MDM2 proteinincreases expression 16797627
16080190
D004317 Doxorubicin Doxorubicin inhibits the reaction [TP53 protein binds to MDM2 protein]affects binding|decreases reaction 19351845
D004317 Doxorubicin Doxorubicin results in increased expression of MDM2 proteinincreases expression 17959036
17653088
14665630
19074854
D004317 Doxorubicin Doxorubicin results in increased phosphorylation of MDM2 proteinincreases phosphorylation 17935137
D004317 Doxorubicin IFNA1 protein promotes the reaction [Doxorubicin results in increased expression of MDM2 protein]increases expression|increases reaction 17959036
D004317 Doxorubicin wortmannin promotes the reaction [Doxorubicin results in increased phosphorylation of MDM2 protein]increases phosphorylation|increases reaction 17935137
D004317 Doxorubicin Doxorubicin results in increased expression of MDM2 mRNAincreases expression 14766674
16949053
D004317 Doxorubicin pifithrin inhibits the reaction [Doxorubicin results in increased expression of MDM2 mRNA]decreases reaction|increases expression 14766674
C034192 ellipticine MDM2 promoter SNP results in decreased susceptibility to ellipticinedecreases response to substance 17575151
D004958 Estradiol Estradiol results in increased expression of MDM2 mRNA alternative formincreases expression 12168835
D004958 Estradiol Estradiol results in increased expression of MDM2 proteinincreases expression 12168835
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of MDM2 mRNAincreases expression 17606305
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of MDM2 mRNA alternative formincreases expression 12168835
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of MDM2 proteinincreases expression 12168835
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of MDM2 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of MDM2 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MDM2 mRNAaffects cotreatment|increases expression 17942748
D005038 Ethylnitrosourea Ethylnitrosourea results in increased expression of MDM2 mRNAincreases expression 19100860
D005038 Ethylnitrosourea Ethylnitrosourea results in increased expression of MDM2 mRNAincreases expression 15954086
D005047 Etoposide benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]]affects binding|increases reaction 17575151
D005047 Etoposide Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]affects binding|increases reaction 17575151
D005047 Etoposide Etoposide results in increased phosphorylation of MDM2 proteinincreases phosphorylation 17935137
D005047 Etoposide MDM2 promoter SNP results in decreased susceptibility to Etoposidedecreases response to substance 17575151
D005047 Etoposide wortmannin promotes the reaction [Etoposide results in increased phosphorylation of MDM2 protein]increases phosphorylation|increases reaction 17935137
D005047 Etoposide Etoposide results in increased expression of MDM2 proteinincreases expression 15459018
D005047 Etoposide Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of MDM2 protein]decreases reaction|increases expression 15459018
D015073 2-Acetylaminofluorene [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of MDM2 proteinaffects cotreatment|affects expression|affects localization 11003613
D005472 Fluorouracil Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of MDM2 protein]increases expression|increases reaction 15546879
D005472 Fluorouracil Fluorouracil results in increased expression of MDM2 mRNAincreases expression 14665630
16557594
17982676
D005472 Fluorouracil Fluorouracil results in increased expression of MDM2 proteinincreases expression 19098008
14665630
15546879
D005472 Fluorouracil TP53 protein promotes the reaction [Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of MDM2 protein]]increases expression|increases reaction 15546879
D005472 Fluorouracil TP53 protein promotes the reaction [Fluorouracil results in increased expression of MDM2 mRNA]increases expression|increases reaction 17982676
D005472 Fluorouracil TP53 protein promotes the reaction [Fluorouracil results in increased expression of MDM2 protein]increases expression|increases reaction 15546879
D005472 Fluorouracil Fluorouracil results in increased expression of MDM2 mRNAincreases expression 16949053
D005492 Folic Acid Folic Acid affects the expression of MDM2 mRNAaffects expression 16361273
D005620 Freund's Adjuvant [Urethane co-treated with Freund's Adjuvant] results in increased expression of MDM2 mRNAaffects cotreatment|increases expression 12400877
D005665 Furosemide Furosemide affects the expression of MDM2 mRNAaffects expression 17497460
C056507 gemcitabine gemcitabine results in increased expression of MDM2 mRNAincreases expression 17039268
C425931 GW 501516 MDM2 protein inhibits the reaction [GW 501516 results in increased activity of PPARB protein]decreases reaction|increases activity 19103650
D017313 Fenretinide Fenretinide results in decreased expression of MDM2 mRNAdecreases expression 16570282
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of and affects the localization of MDM2 proteinaffects localization|increases expression 14689451
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of MDM2 mRNAincreases expression 14689451
C411652 IC 261 IC 261 affects the expression of MDM2 proteinaffects expression 16027726
C051890 irinotecan irinotecan metabolite results in increased expression of MDM2 mRNAincreases expression 15956246
C051890 irinotecan irinotecan results in increased expression of MDM2 mRNAincreases expression 15956246
D007530 Isoflurane Isoflurane results in decreased expression of MDM2 mRNAdecreases expression 16978161
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MDM2 mRNAaffects cotreatment|decreases expression 18544905
C533894 LG 100815 LG 100815 results in increased expression of MDM2 mRNAincreases expression 16951191
D008701 Methapyrilene Methapyrilene results in increased expression of MDM2 mRNAincreases expression 18619722
15890375
D008727 Methotrexate Methotrexate results in increased expression of MDM2 proteinincreases expression 17637740
C030957 methylmercury II [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of MDM2 mRNAaffects cotreatment|increases expression 17905399
D008769 Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in increased expression of MDM2 mRNAincreases expression 12634122
C008480 methylparaoxon methylparaoxon results in increased expression of MDM2 mRNAincreases expression 18418871
D008743 Methyl Parathion Methyl Parathion results in increased expression of MDM2 mRNAincreases expression 18418871
D008942 Mitoxantrone MDM2 promoter SNP results in decreased susceptibility to Mitoxantronedecreases response to substance 17575151
C020300 monomethylarsonic acid monomethylarsonic acid results in increased expression of MDM2 mRNAincreases expression 17481689
D009151 Mustard Gas Mustard Gas results in increased expression of MDM2 mRNAincreases expression 15674843
18955075
D009151 Mustard Gas Mustard Gas affects the expression of MDM2 mRNAaffects expression 15651846
C059685 N(1),N(11)-diethylnorspermine Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of MDM2 protein]increases expression|increases reaction 15546879
C059685 N(1),N(11)-diethylnorspermine N(1),N(11)-diethylnorspermine results in increased expression of MDM2 proteinincreases expression 15546879
C059685 N(1),N(11)-diethylnorspermine TP53 protein promotes the reaction [Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of MDM2 protein]]increases expression|increases reaction 15546879
C059685 N(1),N(11)-diethylnorspermine TP53 protein promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of MDM2 protein]increases expression|increases reaction 15546879
C002741 N-nitrosomorpholine N-nitrosomorpholine results in increased expression of MDM2 proteinincreases expression 14587038
C482205 nutlin 3 nutlin 3 results in increased expression of MDM2 proteinincreases expression 16439685
19098008
16014563
C482205 nutlin 3 TP53 protein affects the reaction [nutlin 3 results in increased expression of MDM2 protein]affects reaction|increases expression 16439685
C482205 nutlin 3 nutlin 3 results in increased expression of MDM2 mRNAincreases expression 16949053
C482205 nutlin 3 nutlin 3 binds to and results in decreased activity of MDM2 proteinaffects binding|decreases activity 16014563
C482205 nutlin 3 nutlin 3 inhibits the reaction [MDM2 protein binds to TP53 protein]affects binding|decreases reaction 16014563
C062198 octa-2,4,6-trienoic acid octa-2,4,6-trienoic acid results in increased expression of MDM2 mRNAincreases expression 16951191
C475587 olomoucine II olomoucine II promotes the reaction [RPL11 protein binds to and results in decreased activity of MDM2 protein]affects binding|decreases activity|increases reaction 16003486
D009942 Organometallic Compounds Organometallic Compounds results in decreased expression of MDM2 proteindecreases expression 17210701
D010100 Oxygen alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 mRNA]]decreases reaction|increases expression|increases reaction 19578757
D010100 Oxygen Oxygen deficiency results in increased expression of MDM2 mRNAincreases expression 19578757
D010100 Oxygen Oxygen deficiency results in increased expression of MDM2 proteinincreases expression 19578757
D010100 Oxygen Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 mRNA]increases expression|increases reaction 19578757
D010100 Oxygen Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 protein]increases expression|increases reaction 19578757
D017239 Paclitaxel MDM2 protein results in decreased susceptibility to Paclitaxeldecreases response to substance 13130078
D010269 Paraquat GPX1 protein affects the reaction [Paraquat affects the expression of MDM2 mRNA]affects expression|affects reaction 12654481
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of MDM2 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital NR1I3 protein promotes the reaction [Phenobarbital results in increased expression of MDM2 mRNA]increases expression|increases reaction 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of MDM2 mRNAincreases expression 19482888
C121565 pifithrin pifithrin inhibits the reaction [Doxorubicin results in increased expression of MDM2 mRNA]decreases reaction|increases expression 14766674
C121565 pifithrin pifithrin inhibits the reaction [Vehicle Emissions results in decreased expression of MDM2 protein]decreases expression|decreases reaction 18940243
C121565 pifithrin pifithrin inhibits the reaction [arsenic trioxide results in increased expression of MDM2 mRNA]decreases reaction|increases expression 17487067
D010882 Piperonyl Butoxide Piperonyl Butoxide results in increased expression of MDM2 mRNAincreases expression 15890375
C006253 pirinixic acid MDM2 protein affects the reaction [pirinixic acid results in increased activity of PPARA protein]affects reaction|increases activity 19103650
C006253 pirinixic acid MDM2 protein promotes the reaction [[pirinixic acid results in increased activity of PPARA protein] which results in increased expression of ACOX1 mRNA]increases activity|increases expression|increases reaction 19103650
C006253 pirinixic acid MDM2 protein promotes the reaction [[pirinixic acid results in increased activity of PPARA protein] which results in increased expression of ANGPTL4 mRNA]increases activity|increases expression|increases reaction 19103650
C006253 pirinixic acid MDM2 protein promotes the reaction [[pirinixic acid results in increased activity of PPARA protein] which results in increased expression of CYP4A1 mRNA]increases activity|increases expression|increases reaction 19103650
C006253 pirinixic acid MDM2 protein promotes the reaction [[pirinixic acid results in increased activity of PPARA protein] which results in increased expression of EHHADH mRNA]increases activity|increases expression|increases reaction 19103650
C006253 pirinixic acid MDM2 protein promotes the reaction [[pirinixic acid results in increased activity of PPARA protein] which results in increased expression of FABP1 mRNA]increases activity|increases expression|increases reaction 19103650
C006253 pirinixic acid MDM2 protein promotes the reaction [pirinixic acid results in increased expression of PPARA protein]increases expression|increases reaction 19103650
C006253 pirinixic acid pirinixic acid promotes the reaction [MDM2 protein binds to PPARA protein]affects binding|increases reaction 19103650
C006253 pirinixic acid pirinixic acid promotes the reaction [[PPARA protein binds to MDM2 protein] which binds to ACOX1 promoter]affects binding|increases reaction 19103650
C006253 pirinixic acid pirinixic acid promotes the reaction [[PPARA protein binds to MDM2 protein] which binds to DBI promoter]affects binding|increases reaction 19103650
C006253 pirinixic acid pirinixic acid results in increased expression of MDM2 mRNAincreases expression 15890375
D010936 Plant Extracts Plant Extracts affects the expression of MDM2 mRNAaffects expression 12878215
D017035 Pravastatin Pravastatin results in increased phosphorylation of MDM2 proteinincreases phosphorylation 15625077
D017035 Pravastatin [Pravastatin results in increased phosphorylation of MDM2 protein] which results in increased degradation of TP53 proteinincreases degradation|increases phosphorylation 15625077
D017035 Pravastatin Sirolimus inhibits the reaction [Pravastatin results in increased phosphorylation of MDM2 protein]decreases reaction|increases phosphorylation 15625077
D017035 Pravastatin U 0126 inhibits the reaction [Pravastatin results in increased phosphorylation of MDM2 protein]decreases reaction|increases phosphorylation 15625077
D017035 Pravastatin Pravastatin results in increased expression of MDM2 proteinincreases expression 15625077
C035988 procymidone procymidone results in decreased expression of MDM2 mRNAdecreases expression 15686871
D011794 Quercetin Quercetin results in decreased phosphorylation of and results in decreased expression of MDM2 proteindecreases expression|decreases phosphorylation 17973296
C059514 resveratrol EGF protein inhibits the reaction [resveratrol inhibits the reaction [TP53 protein binds to MDM2 protein]]affects binding|decreases reaction 15542774
C059514 resveratrol resveratrol inhibits the reaction [TP53 protein binds to MDM2 protein]affects binding|decreases reaction 15542774
C059514 resveratrol resveratrol results in decreased expression of MDM2 mRNAdecreases expression 16998810
C059514 resveratrol resveratrol results in increased expression of MDM2 mRNAincreases expression 15767336
C059514 resveratrol Staurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol inhibits the reaction [TP53 protein binds to MDM2 protein]]]affects binding|decreases reaction 15542774
C059514 resveratrol resveratrol affects the expression of MDM2 proteinaffects expression 16369916
C059514 resveratrol resveratrol results in increased expression of MDM2 mRNAincreases expression 16369916
16081268
D012428 Ruthenium Ruthenium results in decreased expression of MDM2 proteindecreases expression 17210701
D017975 Ruthenium Compounds Ruthenium Compounds results in decreased expression of MDM2 proteindecreases expression 17210701
C064116 S-(1,1,2,2-tetrafluoroethyl)cysteine S-(1,1,2,2-tetrafluoroethyl)cysteine results in increased expression of MDM2 mRNAincreases expression 16678137
D019821 Simvastatin Simvastatin promotes the reaction [Benzo(a)pyrene promotes the reaction [TP53 protein binds to MDM2 protein]]affects binding|increases reaction 15625077
D019821 Simvastatin Simvastatin results in increased phosphorylation of MDM2 proteinincreases phosphorylation 15625077
D020123 Sirolimus Sirolimus inhibits the reaction [Pravastatin results in increased phosphorylation of MDM2 protein]decreases reaction|increases phosphorylation 15625077
C009277 sodium arsenate sodium arsenate results in increased expression of MDM2 mRNAincreases expression 11353140
C017947 sodium arsenite sodium arsenite results in increased expression of MDM2 mRNAincreases expression 12016162
C017947 sodium arsenite sodium arsenite results in increased expression of MDM2 proteinincreases expression 19010883
11813266
C017947 sodium arsenite sodium arsenite results in increased expression of MDM2 mRNAincreases expression 11353140
D019311 Staurosporine Staurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol inhibits the reaction [TP53 protein binds to MDM2 protein]]]affects binding|decreases reaction 15542774
D013629 Tamoxifen Tamoxifen affects the expression of MDM2 mRNAaffects expression 17555576
C508490 TDP 521252 TDP 521252 inhibits the reaction [MDM2 protein binds to TP53 protein]affects binding|decreases reaction 16432175
C508490 TDP 521252 TDP 521252 results in increased expression of MDM2 mRNAincreases expression 16432175
C508490 TDP 521252 TDP 521252 results in increased expression of MDM2 proteinincreases expression 16432175
C508491 TDP 665759 TDP 665759 inhibits the reaction [MDM2 protein binds to TP53 protein]affects binding|decreases reaction 16432175
D013749 Tetrachlorodibenzodioxin alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 mRNA]]decreases reaction|increases expression|increases reaction 19578757
D013749 Tetrachlorodibenzodioxin alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNA]decreases reaction|increases expression 19578757
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 mRNA]increases expression|increases reaction 19578757
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 protein]increases expression|increases reaction 19578757
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of MDM2 mRNAdecreases expression 16039398
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNAincreases expression 19578757
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MDM2 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNAincreases expression 12167310
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of MDM2 protein]decreases reaction|increases expression 15459018
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased degradation of MDM2 proteinincreases degradation 15459018
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of and results in increased phosphorylation of and results in increased activity of MDM2 proteinincreases activity|increases expression|increases phosphorylation 15459018
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased phosphorylation of MDM2 proteinincreases phosphorylation 15459018
D013853 Thioacetamide Thioacetamide results in increased expression of MDM2 mRNAincreases expression 18619722
D014241 Trichloroethylene [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of MDM2 mRNAaffects cotreatment|increases expression 17905399
C113580 U 0126 U 0126 inhibits the reaction [Pravastatin results in increased phosphorylation of MDM2 protein]decreases reaction|increases phosphorylation 15625077
D014520 Urethane [Urethane co-treated with Freund's Adjuvant] results in increased expression of MDM2 mRNAaffects cotreatment|increases expression 12400877
D001335 Vehicle Emissions pifithrin inhibits the reaction [Vehicle Emissions results in decreased expression of MDM2 protein]decreases expression|decreases reaction 18940243
D001335 Vehicle Emissions Vehicle Emissions results in decreased expression of MDM2 proteindecreases expression 18940243
D014750 Vincristine Vincristine results in decreased expression of MDM2 mRNAdecreases expression 16001973
D009536 Niacinamide Niacinamide results in increased expression of MDM2 mRNAincreases expression 16998810
C009687 wortmannin wortmannin promotes the reaction [Doxorubicin results in increased phosphorylation of MDM2 protein]increases phosphorylation|increases reaction 17935137
C009687 wortmannin wortmannin promotes the reaction [Etoposide results in increased phosphorylation of MDM2 protein]increases phosphorylation|increases reaction 17935137
D015215 Zidovudine Zidovudine results in increased expression of MDM2 proteinincreases expression 16797627
D015032 Zinc Zinc affects the expression of MDM2 proteinaffects expression 16636310
D015032 Zinc Zinc binds to and results in increased folding of MDM2 proteinaffects binding|increases folding 16965791
D015032 Zinc Zinc promotes the reaction [MDM2 protein binds to MDM2 protein]affects binding|increases reaction 16965791
D015032 Zinc Zinc promotes the reaction [MDM2 protein binds to MDM4 protein]affects binding|increases reaction 16965791
D015032 Zinc Zinc results in increased ubiquitination of MDM2 proteinincreases ubiquitination 16965791
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.6314745880
MESH:D000014 Abnormalities, Drug-Induced Methotrexate 9.2012039119
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 9.206195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 9.2011752688 14514962 15322242
MESH:D000138 Acidosis Ammonium Chloride 2.6718287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.0317505938
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 3.959612607
MESH:D000168 Acrocephalosyndactylia U 0126 4.6017694057
MESH:D000169 Acrodermatitis Zinc 4.5017202136 17190629 16889938
MESH:D058186 Acute Kidney Injury Cisplatin 13.9817670903 12690470 15814532
MESH:D058186 Acute Kidney Injury Folic Acid 13.9817003819 16595132 16316344
MESH:D058186 Acute Kidney Injury pifithrin 13.9817670903
MESH:D058186 Acute Kidney Injury resveratrol 13.9816538975
MESH:D055371 Acute Lung Injury Oxygen 6.4716759491
MESH:D055371 Acute Lung Injury pirinixic acid 6.4718653653
MESH:D000230 Adenocarcinoma arsenic trioxide 28.6219825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 28.6220127859 20464547
MESH:D000230 Adenocarcinoma Cisplatin 28.6217638652 11798837
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 28.6216033868
MESH:D000230 Adenocarcinoma Doxorubicin 28.6217418594
MESH:D000230 Adenocarcinoma Estradiol 28.6211473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 28.6214692618
MESH:D000230 Adenocarcinoma Fenretinide 28.6210697514
MESH:D000230 Adenocarcinoma Fluorouracil 28.6217638652
MESH:D000230 Adenocarcinoma Urethane 28.6218316556
MESH:D000230 Adenocarcinoma Vincristine 28.6219825857
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Urethane 4.8015814487
MESH:D000236 Adenoma 2-Acetylaminofluorene 35.4310737359
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 35.433712494
MESH:D000236 Adenoma 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 35.4316176798
MESH:D000236 Adenoma Benzo(a)pyrene 35.436695378
MESH:D000236 Adenoma Diethylnitrosamine 35.4310737359 6695378
MESH:D000236 Adenoma Dimethylnitrosamine 35.4319555203
MESH:D000236 Adenoma Ethylnitrosourea 35.436695378
MESH:D000236 Adenoma Folic Acid 35.4316963246
MESH:D000236 Adenoma resveratrol 35.4315688382
MESH:D000236 Adenoma Urethane 35.436695378 17195641 16926031 10530776 10822126 17093202 11497255
MESH:D002759 Adenoma, Bile Duct 2-Acetylaminofluorene 5.096705139
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 17.5916434500 19061943 18056438 17162532 17620307 19052882
MESH:D018248 Adenoma, Liver Cell Phenobarbital 17.5917620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 17.5916434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 17.5916835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.7915276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 3.9917306315 16712894
MESH:D000382 Agricultural Workers' Diseases Paraquat 2.9011874814
MESH:D000419 Albuminuria Doxorubicin 3.6821441931
MESH:D019973 Alcohol-Related Disorders Curcumin 4.1717887948
MESH:D000544 Alzheimer Disease Curcumin 9.1215590663
MESH:D000544 Alzheimer Disease Folic Acid 9.1217116317
MESH:D000544 Alzheimer Disease Plant Extracts 9.1216962711
MESH:D000544 Alzheimer Disease resveratrol 9.1216183991 16162502
MESH:D000544 Alzheimer Disease Zinc 9.1216325427 16580781 17119284 16410023
MESH:D000686 Amyloidosis Diethylstilbestrol 3.6215469931
MESH:D000740 Anemia Fluorouracil 6.0416511603 17963324 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.0411748828
MESH:D000741 Anemia, Aplastic Benzene 3.6417661222 11369114 14761424
MESH:D000743 Anemia, Hemolytic Quercetin 3.4217084956
MESH:D000755 Anemia, Sickle Cell Zinc 4.0416916123
MESH:D000799 Angioedema Acetaminophen 2.9310982225
MESH:D000860 Anoxia Oxygen 4.1620872349
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.2019183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 2.5911256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 8.7315885639
MESH:D001169 Arthritis, Experimental Plant Extracts 8.7314686799
MESH:D001169 Arthritis, Experimental resveratrol 8.7317115116
MESH:D001172 Arthritis, Rheumatoid Curcumin 3.9716807698
MESH:D001172 Arthritis, Rheumatoid Methotrexate 3.9717286800
MESH:D001249 Asthma Mustard Gas 3.9210378619
MESH:D001249 Asthma Zinc 3.9217085522
MESH:D001260 Ataxia Telangiectasia Quercetin 4.0815336622
MESH:D050197 Atherosclerosis Curcumin 7.6218704882
MESH:D050197 Atherosclerosis Oxygen 7.6216391483
MESH:D050197 Atherosclerosis resveratrol 7.6216873680 17967414
MESH:D001321 Autistic Disorder Acetaminophen 2.2818445737
MESH:D001321 Autistic Disorder Folic Acid 2.2821388746
MESH:D001321 Autistic Disorder Homocysteine 2.2820468076 16297937
MESH:D001321 Autistic Disorder Sirolimus 2.2821115397
MESH:D001327 Autoimmune Diseases Curcumin 7.9619761891
MESH:D001327 Autoimmune Diseases Quercetin 7.9619761891
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.101440618 11289319
MESH:D001768 Blister Mustard Gas 4.2619167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 15.3216206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.3219483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.3212125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 15.3219483382
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.8815340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.1215746008
MESH:D001855 Bone Marrow Diseases Benzene 4.3216183116
MESH:D019046 Bone Marrow Neoplasms Cisplatin 15.1314601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 15.1314601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 15.1314601052
MESH:D001859 Bone Neoplasms Paclitaxel 3.7315867366
MESH:D001862 Bone Resorption Freund's Adjuvant 4.3216769263
MESH:D001927 Brain Diseases Ethylnitrosourea 4.0814991843
MESH:D001930 Brain Injuries Zinc 3.8117109824
MESH:D002545 Brain Ischemia Curcumin 12.0116770732
MESH:D002545 Brain Ischemia Plant Extracts 12.0116041641
MESH:D002545 Brain Ischemia resveratrol 12.0117600658
MESH:D001932 Brain Neoplasms Curcumin 14.4117596214
MESH:D001932 Brain Neoplasms Doxorubicin 14.4117150277
MESH:D001932 Brain Neoplasms Ethylnitrosourea 14.4115144691 16651633 16357521 18412241 16436596
MESH:D001932 Brain Neoplasms Fenretinide 14.4116187019
MESH:D001943 Breast Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 27.8820146248
MESH:D001943 Breast Neoplasms Benzene 27.8817162533 11921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 27.8820146248 17474063
MESH:D001943 Breast Neoplasms Cacodylic Acid 27.8817474063
MESH:D001943 Breast Neoplasms Cisplatin 27.8819526202 18382427
MESH:D001943 Breast Neoplasms Curcumin 27.8816243823 18593918 18462866 19250217
MESH:D001943 Breast Neoplasms decitabine 27.8819208741 18320071
MESH:D001943 Breast Neoplasms Diethylnitrosamine 27.8817474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 27.8817129689 15324884
MESH:D001943 Breast Neoplasms docetaxel 27.8816264153 16495393 19526202 15567936 18628466 15692762 17369602
MESH:D001943 Breast Neoplasms Doxorubicin 27.8817369602 16264153 16115903 17426702 11325840 19526202 15634643 15567936 15993339 15136595 16826403 18695136 16322301 18628466 16096432 15939500 17983394 16935488 15668708 18382427 15994142 18234424 15692762 16595493
MESH:D001943 Breast Neoplasms Estradiol 27.8817289903 16675129 12948864 18497071 17261762 14630087 17018787 19861407
MESH:D001943 Breast Neoplasms Etoposide 27.8816322251
MESH:D001943 Breast Neoplasms Fenretinide 27.8816601279
MESH:D001943 Breast Neoplasms Fluorouracil 27.8819217205 18357371 15136595 18608205 16595493 16110121 16557594
MESH:D001943 Breast Neoplasms Folic Acid 27.8816777985
MESH:D001943 Breast Neoplasms gemcitabine 27.8817039268 18382427
MESH:D001943 Breast Neoplasms Methotrexate 27.8816978400
MESH:D001943 Breast Neoplasms Oxygen 27.8817263869
MESH:D001943 Breast Neoplasms Paclitaxel 27.8816244791 18234424 16273361 18223236 18323546 11325840 15136595 16115903
MESH:D001943 Breast Neoplasms Quercetin 27.8818628248
MESH:D001943 Breast Neoplasms resveratrol 27.8816393696 17534123 17651959
MESH:D001943 Breast Neoplasms Tamoxifen 27.8815565566 18997820 19142967 18821012 15668708 18425577 19155303 19288272 18629630 19410462 18855134 19289846 19189212 18351453 19189210 17242785 19011961 20065188 19084267 21138602 16202921 20390343 17893378 20005174 19221464 19059307 20859285 19487384 18815881 19244106 19115204 17440819 20544844 19066611 11161223 18984771 20135344 21152245 17261762 17049068 19200415 16818667 19103187 16273361 16873071
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 27.8820435547
MESH:D001943 Breast Neoplasms Trichloroethylene 27.8815986119
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.2615286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.0617687719 10378619
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.4911589617
MESH:D002057 Burns, Chemical Plant Extracts 4.429625245
MESH:D002105 Cadmium Poisoning Quercetin 4.6316962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.5716111702
MESH:D002276 Carcinoid Tumor Doxorubicin 9.3316051944
MESH:D002276 Carcinoid Tumor Fluorouracil 9.3316051944
MESH:D002277 Carcinoma Curcumin 13.8818593918
MESH:D002277 Carcinoma Dimethylnitrosamine 13.8819555203
MESH:D002277 Carcinoma Fluorouracil 13.8817121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 13.8816835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.6319066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 60.9416705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 60.9416705839
MESH:D006528 Carcinoma, Hepatocellular 2-Acetylaminofluorene 60.943084413 6705139 17761372 3581430 10737359
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 60.943581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 60.943084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 60.9421507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 60.9411135700 14691202 15553829 16217749 15073043
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 60.9417982673
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 60.9419171122 18785209 19208518 17162532 19335982 20101231 19539802 19418558 17055752 20935162 17173139 16935385 16288022 16830150 18210153 20512989 16569478 19822196 18393292 18665156 19052882 20214788 18506893 10737359 10672840 17428255 20727157 18971187 19919837 19519916 17138121 11831363 17761372 21159647 19701751 20524982 16328049 18056438 3084413 16807293 17978847 16681979 3581430 18691550 18788625 16779866 16502159 19394651 20514400 20432363 16878318 16540662 20007298 16698587 18494052 20084675 18978308 19383236 19107877
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 60.9415948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 60.9417876044 18059187 16234567 16023760
MESH:D006528 Carcinoma, Hepatocellular Estradiol 60.9416924424
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 60.9417159502 16270382
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 60.9418930000 16799960 17045692 17971768 16332177 17088986
MESH:D006528 Carcinoma, Hepatocellular N-nitrosomorpholine 60.9415010824 10629087 16935385 19383236 15543204 9311599 9466558 9029167 19335982 1967229 2885971 8364915 1917145 11509945 1701930
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 60.9416313753
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 60.946705139 17173139 1701930 20007298 20935162
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 60.9418834353
MESH:D006528 Carcinoma, Hepatocellular Quercetin 60.9412508355 19519916
MESH:D006528 Carcinoma, Hepatocellular resveratrol 60.9419321006 16227395
MESH:D006528 Carcinoma, Hepatocellular Sirolimus 60.9419335982
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 60.9415276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 60.9416924424
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 60.9417997003
MESH:D018827 Carcinoma, Lewis Lung resveratrol 3.7016675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 6.7116685392 12023789
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 6.7118414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung docetaxel 6.7111894018
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.0717234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 3.9619014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 14.687296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 14.6816201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 14.6818695887
MESH:D002292 Carcinoma, Renal Cell N-nitrosomorpholine 14.687921415 1429202
MESH:D002292 Carcinoma, Renal Cell Vincristine 14.6816201981
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.3112490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 37.0220419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 37.0217066447 6189445 18337622
MESH:D002294 Carcinoma, Squamous Cell Curcumin 37.0218462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 37.0219215824
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 37.0216033868
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 37.026189445
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 37.0216274795
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 37.0218986760 16280240 16757204 17066447
MESH:D002294 Carcinoma, Squamous Cell resveratrol 37.0216227395
MESH:D002294 Carcinoma, Squamous Cell Sirolimus 37.0219435901
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 37.0218572023
MESH:D002294 Carcinoma, Squamous Cell Vincristine 37.026189445
MESH:D002294 Carcinoma, Squamous Cell Zinc 37.0216543248
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 2.8217572228
MESH:D006332 Cardiomegaly Plant Extracts 8.1017645561
MESH:D006332 Cardiomegaly Quercetin 8.1019794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 8.1016120746 18850075 18670907
MESH:D009202 Cardiomyopathies Doxorubicin 2.8817308081 17924179 16952015 16455267 17351982 17007740 16109756 17519947 17131338 15811867 15505089 17382496 15476868 17974986 16364871 16242529 17329180 16278810 16651473 16612575 15792986 17928571 18627295 16269455 16731534
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.5516243910 17334414
MESH:D002318 Cardiovascular Diseases Folic Acid 11.8516755160
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 11.8516936243
MESH:D002318 Cardiovascular Diseases resveratrol 11.8515458977
MESH:D002318 Cardiovascular Diseases Zinc 11.8516936243
MESH:D002386 Cataract Acetaminophen 5.7610977129
MESH:D002386 Cataract Simvastatin 5.7612518039
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 29.736135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 29.737505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 29.7320889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 29.7312371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 29.7317174075 7505956 21159647 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 29.7318566989
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 29.7316003739
MESH:D002471 Cell Transformation, Neoplastic Methylnitronitrosoguanidine 29.732727394
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 29.7320056578 19524636
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.374080065
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 5.0717160924
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 4.5816154183
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 11.6119052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 11.6116835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 11.6118291259
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.399022650 19486331
MESH:D002779 Cholestasis Cyclosporine 13.3919486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.3916919318 17333356 17681005 17110522 16105132 15861022 11677210
MESH:D002779 Cholestasis pirinixic acid 13.3919176532
MESH:D002971 Cleft Lip Folic Acid 3.4221254359
MESH:D002972 Cleft Palate Folic Acid 7.218946559 21254359
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 7.2115668235 15340226 16354765 8697196 12621046
MESH:D002972 Cleft Palate Urethane 7.2112810352
MESH:D003092 Colitis Curcumin 6.9116782535 18200517 16804969
MESH:D003092 Colitis resveratrol 6.9116474422
MESH:D003103 Coloboma Curcumin 3.7318809619
MESH:D003110 Colonic Neoplasms 17-(allylamino)-17-demethoxygeldanamycin 15.5915993848
MESH:D003110 Colonic Neoplasms 6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine 15.5915958644
MESH:D003110 Colonic Neoplasms Curcumin 15.5919359593 16340194
MESH:D003110 Colonic Neoplasms decitabine 15.5917616700
MESH:D003110 Colonic Neoplasms Fluorouracil 15.5916510598 17725105 15001691 17172411 18772588 17169374 17016597 17287894 16340194 17018589
MESH:D003110 Colonic Neoplasms irinotecan 15.5917725105 17287894
MESH:D003110 Colonic Neoplasms Quercetin 15.5911134977 17148506 17191121 19440933 16640504 19056647 15741050
MESH:D003110 Colonic Neoplasms resveratrol 15.5916338953
MESH:D015179 Colorectal Neoplasms arsenic trioxide 16.0520501625
MESH:D015179 Colorectal Neoplasms Cisplatin 16.0515273666
MESH:D015179 Colorectal Neoplasms decitabine 16.0518981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 16.0518802399 18259882
MESH:D015179 Colorectal Neoplasms Fenretinide 16.0517273769
MESH:D015179 Colorectal Neoplasms Fluorouracil 16.0517454858 17594712 18802399 14970324 16303861 16391804 15289873 18448328 16331619 17094418 18383874 17695437 20501625 18288408 16282729 17016601 18509181 17255274 17401013 18949393 16524972 15148649
MESH:D015179 Colorectal Neoplasms Folic Acid 16.0516985020 17116713 16963246 17245555 17087956
MESH:D015179 Colorectal Neoplasms irinotecan 16.0515273666 17159606 17454858 16391804 18509181 18259882 16303861
MESH:D015179 Colorectal Neoplasms Paclitaxel 16.0518802399
MESH:D015179 Colorectal Neoplasms Quercetin 16.0518852136 18095365
MESH:D015179 Colorectal Neoplasms resveratrol 16.0516550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.2817141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.0218497527
MESH:D003324 Coronary Artery Disease Homocysteine 3.3416379339
MESH:D003327 Coronary Disease resveratrol 3.1116507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.3312609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 7.1310525206
MESH:D019465 Craniofacial Abnormalities Benzene 7.1315643154
MESH:D019465 Craniofacial Abnormalities Methotrexate 7.139562676 12039119
MESH:D019465 Craniofacial Abnormalities sodium arsenate 7.1310525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 7.1315322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Zinc 7.1319302082
MESH:D003456 Cryptorchidism Diethylstilbestrol 3.7012952375 16002989
MESH:D003490 Cyanosis 2,4-dinitrotoluene 7.9918551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 7.9918551238
MESH:D003550 Cystic Fibrosis Methotrexate 6.7019747007
MESH:D003550 Cystic Fibrosis Simvastatin 6.7019747007
MESH:D007644 Darier Disease Fluorouracil 3.8916733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.2615213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.4819031437
MESH:D003872 Dermatitis Benzene 3.8915902427
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.0111298694 18759878 14531868 8156756 8970840 12868966 11906362 2524372
MESH:D003876 Dermatitis, Atopic pirinixic acid 1.9218249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 2.663621924 2952479
MESH:D003882 Dermatomyositis Methotrexate 4.2620191521
MESH:D018500 Diabetes Insipidus, Nephrogenic 17-(allylamino)-17-demethoxygeldanamycin 5.3718854434
MESH:D003920 Diabetes Mellitus Zinc 3.4316479319
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 6.0419496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 6.0416873680
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 10.0318403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 10.0320387270
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 10.0316886840
MESH:D003924 Diabetes Mellitus, Type 2 Niacinamide 10.0319647726
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 10.0317107852
MESH:D003928 Diabetic Nephropathies Curcumin 19.9018204486
MESH:D003928 Diabetic Nephropathies Estradiol 19.9019279558
MESH:D003928 Diabetic Nephropathies Plant Extracts 19.9019706694
MESH:D003928 Diabetic Nephropathies resveratrol 19.9016286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 19.9019279558
MESH:D003967 Diarrhea 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol 4.0710611417
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 24.0518551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 24.0521346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 24.0518289764 18648102 11289319 7440962 6482804 8291058 18692083 9653073 9328219 1440618 6679447 16192314 9022650
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 24.0511743745 14725611 12594235 19416960 15619225 11461765 11529661 18071297 19370779 10915739 2444490 15968718 16393943 11421492 10774834 14986274 16081117 17522070 10663392 19739265 12392966 12705907 18713872 17906064 16109766 12540782 16485898 12153990 19420014 11287661 19085960 16227642 19923254 11834606 14550746 16781746 17562736 12958197 19164858 11739529 16177239
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 24.0519107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 24.058172417
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 24.0517416283
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 24.0518186108
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 24.0520420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 24.0512963478
MESH:D056486 Drug-Induced Liver Injury Trichloroethylene 24.057120509
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.1919426721
MESH:D004362 Drug Toxicity Cisplatin 13.8212231392 12649298 19839026 15033597
MESH:D004362 Drug Toxicity Doxorubicin 13.8218602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 13.8211462148
MESH:D004362 Drug Toxicity Zidovudine 13.8215040536
MESH:D004381 Duodenal Ulcer Curcumin 3.2117351913
MESH:D004417 Dyspnea Furosemide 7.8016935035
MESH:D004417 Dyspnea Oxygen 7.8020016425
MESH:D004421 Dystonia Phenobarbital 3.171851702
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 5.0718357618
MESH:D004487 Edema Furosemide 20.4211834646
MESH:D004487 Edema Mustard Gas 20.429260866 11428647 11402378 11428631
MESH:D004487 Edema pirinixic acid 20.4212083418
MESH:D004487 Edema Plant Extracts 20.4212787963
MESH:D004487 Edema resveratrol 20.428985016
MESH:D004487 Edema Staurosporine 20.428273558
MESH:D004487 Edema Tetrachlorodibenzodioxin 20.4212711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 2.9915322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 10.4412538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 10.4417872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 10.4419031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.2019294695
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 3.8016402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 16.4515700306 16804899
MESH:D016889 Endometrial Neoplasms Doxorubicin 16.4517359293
MESH:D016889 Endometrial Neoplasms Estradiol 16.4518566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Folic Acid 16.4517301261
MESH:D016889 Endometrial Neoplasms Tamoxifen 16.4520544844 17893378 19155303 16202921
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.2310568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 11.0318037988
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 11.0315268973
MESH:D020345 Enterocolitis, Necrotizing resveratrol 3.9717923197
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.233659116
MESH:D004828 Epilepsies, Partial Phenobarbital 2.973922381 11558140
MESH:D004827 Epilepsy Phenobarbital 5.1020417680
MESH:D004827 Epilepsy Plant Extracts 5.1019700373 19439326
MESH:D004832 Epilepsy, Absence Phenobarbital 2.776401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.377750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.133659116
MESH:D004890 Erythema Mustard Gas 4.269357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.2016302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 25.663581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 25.6620426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 25.6612903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 25.6616530937
MESH:D004938 Esophageal Neoplasms Cisplatin 25.6616481741 15173087 17638652 16785472 15464296
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 25.6617016578
MESH:D004938 Esophageal Neoplasms docetaxel 25.6616337965
MESH:D004938 Esophageal Neoplasms Fluorouracil 25.6615173087 16337965 17638652 16481741 16785472
MESH:D004938 Esophageal Neoplasms Paclitaxel 25.6616481741
MESH:D004938 Esophageal Neoplasms Zinc 25.6616543248
MESH:D017889 Exfoliation Syndrome Folic Acid 10.4216504073
MESH:D017889 Exfoliation Syndrome Homocysteine 10.4216504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.3011564622
MESH:D005218 Fat Necrosis Thioacetamide 4.8116456712
MESH:D005234 Fatty Liver arsenic trioxide 33.9015073043
MESH:D005234 Fatty Liver Curcumin 33.9019297423
MESH:D005234 Fatty Liver Cyclosporine 33.9019224547
MESH:D005234 Fatty Liver Diethylnitrosamine 33.9021071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 33.9015345470
MESH:D005234 Fatty Liver pirinixic acid 33.9020131406 19236843
MESH:D005234 Fatty Liver Plant Extracts 33.9015975614
MESH:D005234 Fatty Liver Tamoxifen 33.9014986274 19224547
MESH:D005234 Fatty Liver Zidovudine 33.9018299183
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 6.1216002989 16513791 15751030 16611131 16534752
MESH:D052776 Female Urogenital Diseases Tamoxifen 6.1216709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.5811858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.106705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.6314745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 8.4719069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 8.4719069698
MESH:D005355 Fibrosis Curcumin 14.0818705752
MESH:D005355 Fibrosis Cyclosporine 14.0812168785 12639820
MESH:D005355 Fibrosis Quercetin 14.0819474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.0820067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.4016904648
MESH:D005739 Gas Poisoning Oxygen 4.3120016425
MESH:D005756 Gastritis Acetaminophen 13.8816983495
MESH:D005756 Gastritis Folic Acid 13.8817171786
MESH:D005756 Gastritis Zinc 13.8817241300
MESH:D005770 Gastrointestinal Neoplasms Curcumin 3.8218462866
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 9.8416452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 9.8416452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.328708960
MESH:D005901 Glaucoma Folic Acid 9.0616504073
MESH:D005901 Glaucoma Homocysteine 9.0616504073
MESH:D005909 Glioblastoma Curcumin 15.4017596214
MESH:D005909 Glioblastoma Doxorubicin 15.4017150277
MESH:D005909 Glioblastoma Ethylnitrosourea 15.4016436596
MESH:D005909 Glioblastoma Fenretinide 15.4016187019
MESH:D005909 Glioblastoma Quercetin 15.4019804834
MESH:D005910 Glioma Ethylnitrosourea 7.3016651633 18412241 16357521
MESH:D005910 Glioma Fluorouracil 7.3016145905
MESH:D005910 Glioma Quercetin 7.3017643826
MESH:D005911 Gliosis Paraquat 4.2511124998
MESH:D018149 Glucose Intolerance sodium arsenate 4.2419446573
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.207505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.6810696789
MESH:D006086 Graft vs Host Disease Methotrexate 4.2716518429
MESH:D006130 Growth Disorders Zinc 3.3217217573
MESH:D006258 Head and Neck Neoplasms Cisplatin 21.5415102660 15464296
MESH:D006258 Head and Neck Neoplasms Curcumin 21.5418829502 18462866
MESH:D006258 Head and Neck Neoplasms decitabine 21.5419215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 21.5415692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 21.5415162350 15102660 18337622
MESH:D006258 Head and Neck Neoplasms Sirolimus 21.5419435901
MESH:D034381 Hearing Loss Cisplatin 7.6719898482
MESH:D034381 Hearing Loss Furosemide 7.6717868369
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.6515464296
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 11.3820471113
MESH:D006330 Heart Defects, Congenital Folic Acid 11.3817286298 16524890
MESH:D006330 Heart Defects, Congenital Homocysteine 11.3819638421
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.3811294989 10048152
MESH:D006331 Heart Diseases Doxorubicin 12.6616144979 18006777 12587719 16244372 17888722 14766674 18674790 16879835 16244371 17875725 16707910 16495754 16330681
MESH:D006331 Heart Diseases Mitoxantrone 12.6616019553
MESH:D006331 Heart Diseases pifithrin 12.6614766674
MESH:D006331 Heart Diseases Urethane 12.6616046796
MESH:D006333 Heart Failure Doxorubicin 15.5617481944
MESH:D006333 Heart Failure Furosemide 15.5616011733 12660669 16845234
MESH:D006333 Heart Failure pirinixic acid 15.5620558911
MESH:D006333 Heart Failure Plant Extracts 15.5618097624
MESH:D006333 Heart Failure Zinc 15.5617162251
MESH:D006335 Heart Injuries Zinc 4.8517074742
MESH:D016481 Helicobacter Infections Zinc 3.7017241300
MESH:D006390 Hemangioendothelioma 2-Acetylaminofluorene 4.406705139
MESH:D006394 Hemangiosarcoma 2-Acetylaminofluorene 6.716705139
MESH:D006394 Hemangiosarcoma Doxorubicin 6.7115692506
MESH:D006402 Hematologic Diseases Benzene 8.3016183116
MESH:D006402 Hematologic Diseases Zidovudine 8.3012579204
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.5215720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.5211000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 3.7517276928 18665440 15929193
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 6.636705139
MESH:D006505 Hepatitis Thioacetamide 6.6316456712
MESH:D006527 Hepatolenticular Degeneration Zinc 3.8117276780
MESH:D006529 Hepatomegaly Phenobarbital 9.3816109766
MESH:D006529 Hepatomegaly pirinixic acid 9.3819176532 16221962 19772884 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 9.3815340226 16120746 12621046
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.1617701891
MESH:D006558 Herpes Genitalis Estradiol 4.1215709030
MESH:D006561 Herpes Simplex Amsacrine 16.1910809021
MESH:D006561 Herpes Simplex Etoposide 16.1910809021
MESH:D006561 Herpes Simplex Plant Extracts 16.1910715843
MESH:D006561 Herpes Simplex resveratrol 16.1916876885
MESH:D015658 HIV Infections marker/mechanism 12878215
MESH:D015658 HIV Infections Plant Extracts 5.1612878215
MESH:D015658 HIV Infections Zidovudine 5.1611698656 11363243 20032539 17358032 11141242
MESH:D006679 HIV Seropositivity Folic Acid 4.5917209195
MESH:D006689 Hodgkin Disease Cisplatin 14.8616170182 16200630
MESH:D006689 Hodgkin Disease Doxorubicin 14.8615147373 17606976 18501091
MESH:D006689 Hodgkin Disease Etoposide 14.8616200630 15147373 18180244 17606976 16135485
MESH:D006689 Hodgkin Disease sodium arsenite 14.8612676792
MESH:D006689 Hodgkin Disease Vincristine 14.8615147373 16135485 16794504 17606976
MESH:D019584 Hot Flashes Estradiol 7.3317088409
MESH:D019584 Hot Flashes Plant Extracts 7.3317454163 16566672 14716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.138697196 15340226 16959395 18606429 16354765
MESH:D006930 Hyperalgesia Acetaminophen 5.7116870215
MESH:D006930 Hyperalgesia Freund's Adjuvant 5.7116769263
MESH:D006934 Hypercalcemia Furosemide 4.2517652376
MESH:D053565 Hypercalciuria Furosemide 4.7517652376
MESH:D006937 Hypercholesterolemia Curcumin 10.9118704882
MESH:D006937 Hypercholesterolemia Pravastatin 10.9117188708
MESH:D006937 Hypercholesterolemia resveratrol 10.9117188708
MESH:D006943 Hyperglycemia pirinixic acid 6.5920558911
MESH:D006943 Hyperglycemia Quercetin 6.5911834736 18262572
MESH:D020138 Hyperhomocysteinemia Folic Acid 11.2116395265 16865747 16433478 16397167 16755160
MESH:D020138 Hyperhomocysteinemia Homocysteine 11.2117292331 18234410 17369066
MESH:D020138 Hyperhomocysteinemia Plant Extracts 11.2116484555
MESH:D006949 Hyperlipidemias Plant Extracts 6.8415268973 15975614
MESH:D006949 Hyperlipidemias resveratrol 6.8416873680
MESH:D006938 Hyperlipoproteinemia Type II Simvastatin 4.4716238680
MESH:D006962 Hyperparathyroidism, Secondary Furosemide 4.9615086907
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 7.9315034207
MESH:D006965 Hyperplasia Diethylstilbestrol 7.9312960047 14722030
MESH:D006973 Hypertension Benzene 8.6317940673
MESH:D006973 Hypertension Cyclosporine 8.6310903974
MESH:D006973 Hypertension Quercetin 8.6318356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.6318850075 18670907
MESH:D046110 Hypertension, Pregnancy-Induced Furosemide 4.4116612254
MESH:D006984 Hypertrophy Sirolimus 4.4119211884
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.5017488730
MESH:C537153 Hypomagnesemia primary Furosemide 4.7511041285
MESH:D007019 Hypoproteinemia Furosemide 4.9616096441
MESH:D007021 Hypospadias Diethylstilbestrol 8.3316002989
MESH:D007021 Hypospadias Ethinyl Estradiol 8.3316945680 16569931
MESH:D007022 Hypotension Furosemide 7.1111041285
MESH:D007022 Hypotension Isoflurane 7.1112967683
MESH:D007024 Hypotension, Orthostatic Furosemide 4.5115811171
MESH:D020244 Infarction, Middle Cerebral Artery pifithrin 9.0419475672
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 9.0417600658
MESH:D007246 Infertility Diethylstilbestrol 3.5015036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.6312013081
MESH:D007248 Infertility, Male decitabine 10.6417581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 10.6417937319
MESH:D007248 Infertility, Male Paraquat 10.644850670
MESH:D007248 Infertility, Male sodium arsenite 10.6412646999 15346721
MESH:D007249 Inflammation Curcumin 18.7916956363 17151092 18403477
MESH:D007249 Inflammation Diethylnitrosamine 18.7918785209
MESH:D007249 Inflammation Freund's Adjuvant 18.7916793879
MESH:D007249 Inflammation Mustard Gas 18.7911428620 11428647 9260866 16001271 17524151 11402378 8975870 9357497 11428631
MESH:D007249 Inflammation Plant Extracts 18.7916366677 12787963 19332304 15997105
MESH:D007249 Inflammation resveratrol 18.7916366677
MESH:D007249 Inflammation Tamoxifen 18.7919457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 18.7912200463 12878042
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.7618596194 18200517
MESH:D007251 Influenza, Human Quercetin 8.1816624496
MESH:D007251 Influenza, Human resveratrol 8.1816624496
MESH:D007333 Insulin Resistance Estradiol 5.0216393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 5.0216306350
MESH:D007414 Intestinal Neoplasms Curcumin 7.4610783313
MESH:D007414 Intestinal Neoplasms Plant Extracts 7.4612628509 12584176 12351151
MESH:D007511 Ischemia Zinc 3.7616584753
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.108074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.5216580747
MESH:D007627 Keloid Quercetin 4.0717086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.5315604871
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.2315464296
MESH:D007674 Kidney Diseases Acetaminophen 27.3012587719 15629191
MESH:D007674 Kidney Diseases Cisplatin 27.3019839026 12649298 12231392 18289764 15190930
MESH:D007674 Kidney Diseases Cyclosporine 27.3018776723 10903974 8314463
MESH:D007674 Kidney Diseases Doxorubicin 27.3015369732 16775033 15699352
MESH:D007674 Kidney Diseases Estradiol 27.3015618244
MESH:D007674 Kidney Diseases Furosemide 27.3011041285
MESH:D007674 Kidney Diseases Quercetin 27.3016962696
MESH:D007674 Kidney Diseases sodium arsenite 27.3020008137
MESH:D007674 Kidney Diseases Zinc 27.3016960431
MESH:D007676 Kidney Failure, Chronic Doxorubicin 12.1016707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 12.1016518626
MESH:D007676 Kidney Failure, Chronic Zinc 12.1016518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 37.1116705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 37.1116705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 37.116582329
MESH:D007680 Kidney Neoplasms Cyclosporine 37.1112371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 37.1115003126 16762066 14681315
MESH:D007680 Kidney Neoplasms Estradiol 37.1115610895
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 37.1117379185
MESH:D007680 Kidney Neoplasms Fluorouracil 37.1116985049
MESH:D007680 Kidney Neoplasms Tamoxifen 37.1118625569
MESH:D007680 Kidney Neoplasms Zidovudine 37.1112579204
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 3.8911231351
MESH:D007805 Language Development Disorders Methotrexate 4.269562676
MESH:D007859 Learning Disorders Diethylstilbestrol 3.2017184923
MESH:D007889 Leiomyoma Curcumin 3.7318555241
MESH:D007938 Leukemia arsenic trioxide 13.9115070760
MESH:D007938 Leukemia Benzene 13.9118335105 17119257 14694614 15935818
MESH:D007938 Leukemia Curcumin 13.9118462866
MESH:D007938 Leukemia decitabine 13.9118980019 19235587
MESH:D007938 Leukemia Quercetin 13.9117468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.2416085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Mitoxantrone 3.3118172266
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 11.6117077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 11.6116106398
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 11.6120370541
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 8.7816972261
MESH:D007948 Leukemia, Monocytic, Acute U 0126 8.7816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 2.7214633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 11.3819077051
MESH:D007951 Leukemia, Myeloid Benzene 11.3817506065
MESH:D007951 Leukemia, Myeloid decitabine 11.3819117987 18454857 17236224
MESH:D015470 Leukemia, Myeloid, Acute Amsacrine 6.6015148258 18043129
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 6.6016467208 16968895 19850784 17050201 20471514
MESH:D015470 Leukemia, Myeloid, Acute Benzene 6.6019478238
MESH:D015470 Leukemia, Myeloid, Acute decitabine 6.6018206229 19387464 18704418 17679729 18460780 19010910
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.5518055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 5.6119642359 15622746 19075265 17217047 16891316 9834237 16966277 17869043 17712046 15336539 15213294 15748426 17649720 16330433 17107899 11161223 12712474 12018890 16823087 16331271 19225113 12679006 19035177 11468182 16112521
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 5.6116087638
MESH:D015458 Leukemia, T-Cell arsenic trioxide 8.8616882451
MESH:D015458 Leukemia, T-Cell Curcumin 8.8616106398
MESH:D007972 Leukoplakia, Oral Fenretinide 5.1316707609
MESH:D008064 Lipidoses Tamoxifen 2.4717567588 15342952
MESH:D008080 Liposarcoma Paclitaxel 3.9817353645
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 11.0320032147 18522880 18665156 18407596 19638242
MESH:D008103 Liver Cirrhosis Methotrexate 11.0314986274
MESH:D008103 Liver Cirrhosis Phenobarbital 11.0321047994
MESH:D008103 Liver Cirrhosis Plant Extracts 11.0317157831
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.569327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 15.9018006644 18705752 17355460
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 15.9015577212 12918455 14643895 15733078 17724770 15864749 17198567 17036385 18637143 16042886 15383259 14659978 14726149 15086199 17201889 17432682 15369754 15138612 16009107 15067225 15793283 17881167 15744066 17640959 17534399 18237412 16627068 16603200 15479170 17348192 18239293 15723089 14568256 15842777 15504291 16544323 15798949 15591649 16169303 18210741 18629640 17196135 18567088 15942678 17465448 17666798 15571005 18364076 15161499 15081153 16570917 15099470 14709902 15763062 15366600 15339415 15492853 17203207 18095165 18672772 16270385 18371158 12925901 17719030 15298665
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 15.9016595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 15.9014659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 15.9015474484
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 15.9015479170
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 15.9012741479
MESH:D008106 Liver Cirrhosis, Experimental Sirolimus 15.9017050028
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 15.9018564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 15.9012878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 15.9014739098 16248980 18395095 17292413 18606216 15288472 12891558 18031379 16098781 11172339 12557150 18380797 15465738 15095483 16511523 18295389 17127702 18032466 12085344 15078482 18615449 17629604 15362042 11682029 18263696 15158331 15288473 16126171 10677585 15075984 12679928 15474484 16097051 15316131 16489207 12531686 12175628 15716488 15334695 16343077 17050028 17355460 18416461 18458672 11481614
MESH:D008107 Liver Diseases Acetaminophen 13.9516611625 19014921 12587719 12969438 16610002 19460945 11587558 19784758
MESH:D008107 Liver Diseases Curcumin 13.9516956363
MESH:D008107 Liver Diseases Diethylnitrosamine 13.9517034775
MESH:D008107 Liver Diseases Folic Acid 13.9516877991
MESH:D008107 Liver Diseases Phenobarbital 13.9519363144
MESH:D008107 Liver Diseases Plant Extracts 13.9517034775
MESH:D008107 Liver Diseases Thioacetamide 13.9518374380 16337175 15158337
MESH:D017114 Liver Failure, Acute Acetaminophen 11.7416871587 17185352
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 11.7417457977
MESH:D017114 Liver Failure, Acute Thioacetamide 11.7417276928 12479984 15313186 15633222
MESH:D008113 Liver Neoplasms 10-hydroxycamptothecin 74.6316603448
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 74.637678174
MESH:D008113 Liver Neoplasms 2-Acetylaminofluorene 74.6318001218 14678523 16273603 11376686 10672840 10737359
MESH:D008113 Liver Neoplasms 2-nitrofluorene 74.6315890375
MESH:D008113 Liver Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 74.6315890375
MESH:D008113 Liver Neoplasms Aflatoxin B1 74.6315890375 9163691 18177683 2125692
MESH:D008113 Liver Neoplasms arsenic trioxide 74.6314682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 74.6320195826 21137059
MESH:D008113 Liver Neoplasms Diethylnitrosamine 74.6312112319 19256749 12771043 19551842 19499222 10737359 20137499 20492335 18977376 20434301 19638242 20405173 20452335 19642983 19833225 19850985 18644402 9163691 18754104 19090486 19690152 21167192 20101389 19294768 19812893 20583210 19426721 2422723 21047994 19996281 19254457 19073162 18648771 15885732 15175105 19255062 21278145 2862719 19427195 18978307 16942905 20118626 21071580 20501860
MESH:D008113 Liver Neoplasms Diethylstilbestrol 74.6315890375 16712894
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 74.6315890375 3113478
MESH:D008113 Liver Neoplasms Fluorouracil 74.6318383874 17045692 16603448 15113037
MESH:D008113 Liver Neoplasms Methapyrilene 74.6315890375
MESH:D008113 Liver Neoplasms Phenobarbital 74.6319812893 8742319 19073162 19482888 21047994 15975961
MESH:D008113 Liver Neoplasms Piperonyl Butoxide 74.6318648771 20101389 19690152 15890375
MESH:D008113 Liver Neoplasms pirinixic acid 74.6315890375 20007298 16377806
MESH:D008113 Liver Neoplasms Plant Extracts 74.6319168119
MESH:D008113 Liver Neoplasms Quercetin 74.6318980244
MESH:D008113 Liver Neoplasms resveratrol 74.6319321006 19812893 20405173 19073162
MESH:D008113 Liver Neoplasms sodium arsenite 74.6316712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 74.6316684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 74.6316984957
MESH:D008113 Liver Neoplasms Urethane 74.6317093202 17559639 16391232
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 50.592876786 2876784 6135515
MESH:D008114 Liver Neoplasms, Experimental 2-Acetylaminofluorene 50.596150874 1399818 534488
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 50.59598648 3712494 1399818 6587162
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 50.598603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 50.5920377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 50.5912562636
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 50.5918775883 18282651 18093689 2563599 16267830 17854601 3124819 18308698 18544905 9362446 19009564 18253720 19539802 17942915 18079962 18164116 19126423 19004024 19519916 21159647 17174075 16842330
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 50.5915603536 6150874 1848544
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 50.5916842330 17085340
MESH:D008114 Liver Neoplasms, Experimental kojic acid 50.5918544905
MESH:D008114 Liver Neoplasms, Experimental o-Aminoazotoluene 50.5911398193 16267830 10887293 15346788 12882633
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 50.591399818 18308698 17172636 6150874 2563599
MESH:D008114 Liver Neoplasms, Experimental Quercetin 50.5919519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 50.5912151625
MESH:D008114 Liver Neoplasms, Experimental Trichloroethylene 50.597955063
MESH:D008133 Long QT Syndrome arsenic trioxide 2.6315213294
MESH:D008171 Lung Diseases Mustard Gas 5.3318702808 18161513
MESH:D008171 Lung Diseases sodium arsenite 5.3319095001
MESH:D017563 Lung Diseases, Interstitial Benzene 8.6514698565
MESH:D017563 Lung Diseases, Interstitial Methotrexate 8.6518516814
MESH:D055370 Lung Injury Oxygen 3.6518339021
MESH:D008175 Lung Neoplasms 2-Acetylaminofluorene 47.3411376686
MESH:D008175 Lung Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 47.3418508827 14755239 15893417 18813816 19931552 16061637 12438228 16401635 15172992 17139156 9255578
MESH:D008175 Lung Neoplasms Aflatoxin B1 47.3414755239
MESH:D008175 Lung Neoplasms arsenic trioxide 47.3411798837 19825857
MESH:D008175 Lung Neoplasms Benzene 47.3412562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 47.3417053015 18816296 20064080 18569708 6695378 20869020 20135361 20464547 18520028
MESH:D008175 Lung Neoplasms Cisplatin 47.346189445 17225452 11798837
MESH:D008175 Lung Neoplasms Curcumin 47.3418462866 19359593 16243823
MESH:D008175 Lung Neoplasms Diethylnitrosamine 47.346695378 20970405 20512841 21163286
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 47.3411884234 16061637 19555203
MESH:D008175 Lung Neoplasms Doxorubicin 47.3417418594 6189445
MESH:D008175 Lung Neoplasms Ethylnitrosourea 47.346695378 16271038 17703301 16019985
MESH:D008175 Lung Neoplasms Fluorouracil 47.3415246190
MESH:D008175 Lung Neoplasms Mustard Gas 47.348781369 3148597
MESH:D008175 Lung Neoplasms Plant Extracts 47.3420869020
MESH:D008175 Lung Neoplasms Quercetin 47.3416280456
MESH:D008175 Lung Neoplasms sodium arsenite 47.3417306315 17077188 16712894 19931552 15276417
MESH:D008175 Lung Neoplasms Tamoxifen 47.3418625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 47.3411884234 19555203
MESH:D008175 Lung Neoplasms Urethane 47.3416926031 11544531 16289808 16337739 16204055 17093202 16007126 11497255 11323394 12957351 17255336 17195641 15902970 12117781 10822126 7750092 6695378 16788158 15136453 10530776 12765245 12466968 11893704 11246140 11074608 10779650 10997738 16391232 11992545 11062179 15166089 11552296 11807781 11307925 14587096
MESH:D008175 Lung Neoplasms Vehicle Emissions 47.349255578
MESH:D008175 Lung Neoplasms Vincristine 47.3419825857 6189445
MESH:D008175 Lung Neoplasms Zidovudine 47.3418800350
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 3.8915086387
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.0017718048
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.2515166399
MESH:D008223 Lymphoma Benzene 33.8617119257 17584886
MESH:D008223 Lymphoma Chlorambucil 33.8610745627
MESH:D008223 Lymphoma Curcumin 33.8618462866
MESH:D008223 Lymphoma decitabine 33.8619470736
MESH:D008223 Lymphoma Diethylstilbestrol 33.8615700306
MESH:D008223 Lymphoma Doxorubicin 33.8616098063
MESH:D008223 Lymphoma Ethylnitrosourea 33.8615790496
MESH:D008223 Lymphoma Etoposide 33.8612556972 12854902
MESH:D008223 Lymphoma Methotrexate 33.8617352296
MESH:D016393 Lymphoma, B-Cell resveratrol 3.4617088997
MESH:D017728 Lymphoma, Large-Cell, Anaplastic 17-(allylamino)-17-demethoxygeldanamycin 5.7217157164
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 10.2417654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 10.2414749477
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 10.2414749477
MESH:D016399 Lymphoma, T-Cell Curcumin 14.4316173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 14.4315621674
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 14.4315375218
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.6016002989
MESH:D015674 Mammary Neoplasms, Animal Benzene 11.6812562636
MESH:D015674 Mammary Neoplasms, Animal resveratrol 11.6815688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 11.6819428831
MESH:D008325 Mammary Neoplasms, Experimental Benzene 22.2811921183
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 22.2815458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 22.2811408345 11807958 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 22.2810767621 18041768 10838139
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 22.2810697514
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 22.2811606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 22.2816827153 14580682 19196722 11731420 19196723
MESH:D008325 Mammary Neoplasms, Experimental Zinc 22.2812773700
MESH:D020149 Manganese Poisoning Estradiol 9.6219453300
MESH:D020149 Manganese Poisoning Tamoxifen 9.6219453300
MESH:D019767 Maxillofacial Abnormalities Folic Acid 4.8016832597
MESH:D008545 Melanoma marker/mechanism 17210701
MESH:D008545 Melanoma Cisplatin 30.4617761969 16432458 11135225 18505091 18332650 16809738 12883367 18176117 12393984 15577323 12374674 17023156 16248763
MESH:D008545 Melanoma Curcumin 30.4618462866 17885582
MESH:D008545 Melanoma decitabine 30.4617785578 16505122
MESH:D008545 Melanoma docetaxel 30.4612417787
MESH:D008545 Melanoma Doxorubicin 30.4616827129
MESH:D008545 Melanoma Fenretinide 30.4616270382
MESH:D008545 Melanoma Organometallic Compounds 30.4617210701
MESH:D008545 Melanoma Paclitaxel 30.4612025231 16342250 12040289
MESH:D008545 Melanoma resveratrol 30.4617992120
MESH:D008545 Melanoma Ruthenium 30.4617210701
MESH:D008545 Melanoma Ruthenium Compounds 30.4617210701
MESH:D008545 Melanoma Sirolimus 30.4619282848
MESH:D008545 Melanoma sodium arsenite 30.4616487513 19082730
MESH:D008545 Melanoma Tamoxifen 30.4612393984 19393235
MESH:D018328 Melanoma, Amelanotic Cisplatin 14.5115990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 14.5115990972
MESH:D018328 Melanoma, Amelanotic Vincristine 14.5115990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.6919513568
MESH:D008569 Memory Disorders Curcumin 3.3117263510
MESH:D008579 Meningioma Ethylnitrosourea 5.0717943659
MESH:D008591 Meningomyelocele Homocysteine 4.6616602021
MESH:D008654 Mesothelioma Cisplatin 4.8917638057
MESH:D008654 Mesothelioma Doxorubicin 4.8917638057
MESH:D008659 Metabolic Diseases resveratrol 3.5617112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 3.8716801185
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 4.9217358032
MESH:D053842 Microsatellite Instability Methylnitronitrosoguanidine 4.9917671175
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.6815792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 14.6316381670
MESH:D009062 Mouth Neoplasms Fenretinide 14.6316274795
MESH:D009062 Mouth Neoplasms Fluorouracil 14.6316757204 18986760
MESH:D009062 Mouth Neoplasms Sirolimus 14.6319435901
MESH:D052016 Mucositis Doxorubicin 15.9717415656
MESH:D052016 Mucositis irinotecan 15.9717159606
MESH:D052016 Mucositis Methotrexate 15.9717488658
MESH:D009101 Multiple Myeloma arsenic trioxide 19.3619549372 19417148 15949261 11468182 14977855
MESH:D009101 Multiple Myeloma Benzene 19.3617119195
MESH:D009101 Multiple Myeloma Curcumin 19.3619372569
MESH:D009101 Multiple Myeloma decitabine 19.3618172295
MESH:D009101 Multiple Myeloma Paclitaxel 19.3614749477
MESH:D009101 Multiple Myeloma resveratrol 19.3617049120 16267019 16490592 17164350 17935668 14749477
MESH:D009128 Muscle Spasticity 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol 5.2017220914
MESH:D009134 Muscular Atrophy, Spinal Curcumin 9.4417962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 9.4417962980
MESH:D009135 Muscular Diseases GW 501516 8.1516239165
MESH:D009135 Muscular Diseases pirinixic acid 8.1516239165
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 4.0418186108
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.7618349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 5.5016882451 16105982
MESH:D009190 Myelodysplastic Syndromes decitabine 5.5019157545 16882708 19010910 18608210
MESH:D009203 Myocardial Infarction Doxorubicin 19.7215857846 19429709
MESH:D009203 Myocardial Infarction Homocysteine 19.7217412321
MESH:D009203 Myocardial Infarction pirinixic acid 19.7219151258
MESH:D009203 Myocardial Infarction Pravastatin 19.7217188708
MESH:D009203 Myocardial Infarction Quercetin 19.7219595682
MESH:D009203 Myocardial Infarction resveratrol 19.7217015251 16525036 16317513 17188708 16456233 17125593
MESH:D009203 Myocardial Infarction Vincristine 19.7217284715
MESH:D017202 Myocardial Ischemia resveratrol 6.5317125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 6.5312213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 9.9716810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 9.9716411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 9.9719207477
MESH:D009205 Myocarditis resveratrol 3.8617322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.5817484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 7.3918551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 7.3918551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 7.4916624393
MESH:D009361 Neoplasm Invasiveness Curcumin 7.4918495463
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 16.353581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 16.359029167 3581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 16.3518259882
MESH:D009362 Neoplasm Metastasis irinotecan 16.3518259882
MESH:D009362 Neoplasm Metastasis Paclitaxel 16.3515867366
MESH:D009362 Neoplasm Metastasis Tamoxifen 16.3519393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.1319410462
MESH:D009369 Neoplasms marker/mechanism
MESH:D009369 Neoplasms Benzo(a)pyrene 40.0711141357
MESH:D009369 Neoplasms Cisplatin 40.0716773208
MESH:D009369 Neoplasms decitabine 40.0719116145 19470736 17925555
MESH:D009369 Neoplasms Diethylstilbestrol 40.0715313581
MESH:D009369 Neoplasms Fenretinide 40.0715958647 17353921
MESH:D009369 Neoplasms Fluorouracil 40.0718239605 18600527 16928823
MESH:D009369 Neoplasms Mitoxantrone 40.0716640825
MESH:D009369 Neoplasms pirinixic acid 40.0717405874
MESH:D009369 Neoplasms Quercetin 40.0715185748
MESH:D009369 Neoplasms sodium arsenite 40.0711559025
MESH:D009369 Neoplasms TDP 521252 40.0716432175
MESH:D009369 Neoplasms TDP 665759 40.0716432175
MESH:D009369 Neoplasms Trichloroethylene 40.0711911487
MESH:D009369 Neoplasms Urethane 40.0715625555
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 14.7316707424
MESH:D009374 Neoplasms, Experimental resveratrol 14.738985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 14.7320056578
MESH:D009374 Neoplasms, Experimental Urethane 14.7315582191
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 7.8312497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 7.8319189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 2.8517289903
MESH:D009395 Nephritis, Interstitial Cisplatin 3.5915464296
MESH:D009397 Nephrocalcinosis Furosemide 4.9615086907
MESH:D009401 Nephrosis Doxorubicin 3.8916636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.5317954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 6.7018481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 6.7015640375 16889571
MESH:D009410 Nerve Degeneration Paraquat 3.0016893418
MESH:D009421 Nervous System Malformations Diethylstilbestrol 11.4511399458
MESH:D009421 Nervous System Malformations Estradiol 11.4516427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 11.4514600291
MESH:D009423 Nervous System Neoplasms Curcumin 4.7218462866
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 19.986679447
MESH:D009436 Neural Tube Defects arsenic trioxide 19.9810525206
MESH:D009436 Neural Tube Defects Benzene 19.9815643154
MESH:D009436 Neural Tube Defects Folic Acid 19.9817438019
MESH:D009436 Neural Tube Defects sodium arsenate 19.9819446573 11749123 18186108 10525206
MESH:D009436 Neural Tube Defects sodium arsenite 19.9812854658
MESH:D009442 Neurilemmoma Ethylnitrosourea 4.5216651423 17160924 16003739
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 4.3017168769
MESH:D009447 Neuroblastoma Cisplatin 8.278761367
MESH:D009447 Neuroblastoma Doxorubicin 8.2715555623
MESH:D009447 Neuroblastoma irinotecan 8.278761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 9.6718514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 9.6720387270
MESH:D019636 Neurodegenerative Diseases resveratrol 9.6717652729
MESH:D017599 Neuroectodermal Tumors Cisplatin 14.078761367
MESH:D017599 Neuroectodermal Tumors irinotecan 14.078761367
MESH:D017599 Neuroectodermal Tumors Vincristine 14.0712837982
MESH:D020078 Neurogenic Inflammation Quercetin 7.9117929310
MESH:D020078 Neurogenic Inflammation resveratrol 7.9117929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.2020387270
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 4.7816303764
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 6.3316436463
MESH:D020258 Neurotoxicity Syndromes Methyl Parathion 6.3319784758
MESH:D009503 Neutropenia Folic Acid 6.8316322990
MESH:D009503 Neutropenia Mustard Gas 6.837688884 16761898
MESH:D053206 Nocturnal Enuresis Furosemide 4.9617945291
MESH:D009765 Obesity Curcumin 5.5619297423
MESH:D009765 Obesity pirinixic acid 5.5620558911
MESH:D009765 Obesity Plant Extracts 5.5619056576 20132043
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 15.0916049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 15.0916049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 15.096482804 4026338
MESH:D009784 Occupational Diseases Benzene 15.0915935809 17119257 15612468 17178637 16737584 17479406 15913788 15576619 15727169
MESH:D009837 Oligodendroglioma Ethylnitrosourea 5.0717160924
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.103988306
MESH:D010014 Osteolysis Paclitaxel 4.0815867366
MESH:D010018 Osteomalacia Phenobarbital 3.4717016548
MESH:D010024 Osteoporosis Curcumin 2.8618719352
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 7.4319495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 7.4317513867
MESH:D012516 Osteosarcoma Doxorubicin 3.3615930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 34.4119769630 12452020 16624393
MESH:D010051 Ovarian Neoplasms Benzene 34.4112562636
MESH:D010051 Ovarian Neoplasms Cisplatin 34.4115464296 19769630 17225452 6897625
MESH:D010051 Ovarian Neoplasms Curcumin 34.4118462866 19020741
MESH:D010051 Ovarian Neoplasms decitabine 34.4119331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 34.4119401270
MESH:D010051 Ovarian Neoplasms Fenretinide 34.4116133793
MESH:D010051 Ovarian Neoplasms Paclitaxel 34.4111161223
MESH:D010051 Ovarian Neoplasms Quercetin 34.4119005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 34.4115276417 17306315
MESH:D010051 Ovarian Neoplasms U 0126 34.4116211241
MESH:D010051 Ovarian Neoplasms Urethane 34.4116391232
MESH:D010146 Pain Acetaminophen 1.6916870215
MESH:D010190 Pancreatic Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 36.8812384795
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 36.8815580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 36.8819003803
MESH:D010190 Pancreatic Neoplasms Curcumin 36.8817440100 19196508 19401701
MESH:D010190 Pancreatic Neoplasms decitabine 36.8819294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 36.8816540662
MESH:D010190 Pancreatic Neoplasms Etoposide 36.8819003803
MESH:D010190 Pancreatic Neoplasms Fenretinide 36.8815580305
MESH:D010190 Pancreatic Neoplasms Fluorouracil 36.8816500647 16929163 15113037 19003803
MESH:D010190 Pancreatic Neoplasms gemcitabine 36.8811504793 18383843 18992248 17440100 16929163
MESH:D010190 Pancreatic Neoplasms Phenobarbital 36.8816965848
MESH:D010190 Pancreatic Neoplasms Quercetin 36.8816965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.8511578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 10.647296757
MESH:D010212 Papilloma Hydrogen Peroxide 10.6412065085
MESH:D010212 Papilloma Plant Extracts 10.6416517061 15173996
MESH:D010235 Paraganglioma arsenic trioxide 3.3219927285
MESH:D010300 Parkinson Disease Homocysteine 6.3616275827
MESH:D010300 Parkinson Disease Paraquat 6.3612911755 16140633 11445065 15824117 15451049 11124998 11181820 16510128
MESH:D010300 Parkinson Disease Sirolimus 6.3619682553
MESH:D010302 Parkinson Disease, Secondary Paraquat 3.5616190885
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.3312520081
MESH:D010391 Pemphigoid, Bullous Niacinamide 5.5311026799
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.4615464296
MESH:D010538 Peritonitis Isoflurane 4.3517414419
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 3.566228378
MESH:D003557 Phyllodes Tumor Doxorubicin 4.2417983394
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.2614722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 9.2215687265 16977796
MESH:D010911 Pituitary Neoplasms Urethane 9.2216391232
MESH:D010997 Pleural Neoplasms Cisplatin 10.9117638057
MESH:D010997 Pleural Neoplasms Doxorubicin 10.9117638057
MESH:D011014 Pneumonia Paraquat 3.5612504350
MESH:D011041 Poisoning Methyl Parathion 6.5217603234
MESH:D011041 Poisoning Mustard Gas 6.5215727166
MESH:D011085 Polycystic Ovary Syndrome Simvastatin 4.5317105841
MESH:D011141 Polyuria Furosemide 4.7517945291
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.7018163543
MESH:D011230 Precancerous Conditions Cyclosporine 15.5212371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 15.522563599
MESH:D011230 Precancerous Conditions Phenobarbital 15.522563599
MESH:D011230 Precancerous Conditions Quercetin 15.5219056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Vincristine 4.0421297632
MESH:D011225 Pre-Eclampsia Zinc 3.4517114810
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 11.1817184923
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 11.1816679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 11.1811118676 11222880 11896295 11399792
MESH:D055728 Primary Myelofibrosis decitabine 3.8517616702
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.0620887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 8.0519131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 8.0517292933
MESH:D011471 Prostatic Neoplasms Curcumin 8.0518156803 18769126 12497104 10851300 15129424 11398177 18226269
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 8.0517136230 15846301 15046698
MESH:D011471 Prostatic Neoplasms docetaxel 8.0518824434 19103299 16644109 16520278
MESH:D011471 Prostatic Neoplasms Doxorubicin 8.0516888761 16729912 16868541 15749863 18437689 15897917
MESH:D011471 Prostatic Neoplasms Estradiol 8.0516740699
MESH:D011471 Prostatic Neoplasms Etoposide 8.0517172428
MESH:D011471 Prostatic Neoplasms Fenretinide 8.0517024972
MESH:D011471 Prostatic Neoplasms Fluorouracil 8.0518626508 19082440
MESH:D011471 Prostatic Neoplasms Paclitaxel 8.0517136230 16356831 16729912 17172428
MESH:D011471 Prostatic Neoplasms Plant Extracts 8.0517804756 14666653
MESH:D011471 Prostatic Neoplasms Quercetin 8.0514715546 17292933
MESH:D011471 Prostatic Neoplasms resveratrol 8.0517804756 16731767 17636462 17718901 17675339 15767336
MESH:D011471 Prostatic Neoplasms sodium arsenite 8.0516039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 8.0515067354
MESH:D011471 Prostatic Neoplasms Zinc 8.0516700911 16517595 16606632 12429649
MESH:D011537 Pruritus Ethinyl Estradiol 6.5816919318 15861022
MESH:D011537 Pruritus Mustard Gas 6.5818058305
MESH:D019310 Pseudolymphoma Phenobarbital 3.5812752131
MESH:D011565 Psoriasis Cyclosporine 4.4916882103
MESH:D011565 Psoriasis Methotrexate 4.4917410198
MESH:D011656 Pulmonary Emphysema Curcumin 3.7219168576
MESH:D011658 Pulmonary Fibrosis Mustard Gas 4.3617894541 17620002 10334151 17720292 17266442
MESH:D011658 Pulmonary Fibrosis Paraquat 4.3617997886 16324872
MESH:D012004 Rectal Neoplasms Fluorouracil 3.2318722050 18286688 15538739 16160472
MESH:D051437 Renal Insufficiency Cisplatin 17.3415464296
MESH:D051437 Renal Insufficiency Doxorubicin 17.3417922066
MESH:D051437 Renal Insufficiency Folic Acid 17.3415728788
MESH:D051437 Renal Insufficiency Methotrexate 17.3417352296
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.6716325855
MESH:D015427 Reperfusion Injury Furosemide 7.9116526316
MESH:D015427 Reperfusion Injury pirinixic acid 7.9119058328
MESH:D015427 Reperfusion Injury resveratrol 7.9116317513 16314181 15827377 17520802 17058453
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 14.8718379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Furosemide 14.8712394941 15912074 16096441
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 14.8717627322 18339021
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 14.8711700416
MESH:D012135 Respiratory Sounds Paraquat 7.2611874814
MESH:D012135 Respiratory Sounds Vehicle Emissions 7.2618950799
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 2.9818990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 15.473692021
MESH:D012162 Retinal Degeneration Fenretinide 15.4716303925
MESH:D012162 Retinal Degeneration Paraquat 15.4716458197
MESH:D012162 Retinal Degeneration Zinc 15.4716584753
MESH:D012208 Rhabdomyosarcoma decitabine 3.5619155313
MESH:D012509 Sarcoma Curcumin 6.9218462866
MESH:D012509 Sarcoma Doxorubicin 6.9216767912 18313854 15675481 17710206 17203757 15625365
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 17.6616646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 17.6614601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 17.6614601052 16326096
MESH:D012512 Sarcoma, Ewing's Etoposide 17.6614601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 3.8917846226
MESH:D012554 Schistosomiasis japonica Quercetin 4.6316862918
MESH:D012559 Schizophrenia Folic Acid 3.5516641680
MESH:D012559 Schizophrenia Homocysteine 3.5516641680
MESH:D012640 Seizures 2,4-dinitrotoluene 5.9918551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.9918551238
MESH:D012640 Seizures Phenobarbital 5.993137016 11442880 4039156 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 3.926407741
MESH:D018805 Sepsis Curcumin 7.2818389075
MESH:D018805 Sepsis Isoflurane 7.2817414419
MESH:D012871 Skin Diseases Folic Acid 6.2418709164
MESH:D012871 Skin Diseases monomethylarsonic acid 6.2421378128
MESH:D012871 Skin Diseases Mustard Gas 6.2416961503 15451306 12880345
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 26.6110029692 19755658
MESH:D012878 Skin Neoplasms Doxorubicin 26.6115692506
MESH:D012878 Skin Neoplasms Fenretinide 26.6116467112
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 26.6112065085
MESH:D012878 Skin Neoplasms Plant Extracts 26.6115173996 16517061
MESH:D012878 Skin Neoplasms resveratrol 26.618985016 15837718
MESH:D012878 Skin Neoplasms sodium arsenite 26.6119524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 26.6116192470
MESH:D012878 Skin Neoplasms Urethane 26.6111807781
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.4315464296
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.6917203757 16767912 15625365
MESH:D013088 Spermatocele Diethylstilbestrol 14.8916709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 14.8916709447
MESH:D013088 Spermatocele Tamoxifen 14.8916709447
MESH:D013118 Spinal Cord Diseases Folic Acid 4.5916361298
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.1519457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.0612854658
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.3612587719
MESH:D013274 Stomach Neoplasms arsenic trioxide 22.7417007042
MESH:D013274 Stomach Neoplasms Benzene 22.7412562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 22.742093021 20155912
MESH:D013274 Stomach Neoplasms Cisplatin 22.7415958060 18396642 17522103
MESH:D013274 Stomach Neoplasms decitabine 22.7419037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 22.7418456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 22.7416033868
MESH:D013274 Stomach Neoplasms docetaxel 22.7416557585
MESH:D013274 Stomach Neoplasms Fluorouracil 22.7418567086 17522103 19015929 18396642 17172411 16424979 15786421 19084572 17498489 16951190
MESH:D013274 Stomach Neoplasms Folic Acid 22.7417171786
MESH:D013274 Stomach Neoplasms Furosemide 22.7417052386
MESH:D013274 Stomach Neoplasms irinotecan 22.7415723263
MESH:D013274 Stomach Neoplasms Paclitaxel 22.7418506536 18396642
MESH:D013274 Stomach Neoplasms Zidovudine 22.7417696246
MESH:D013276 Stomach Ulcer Curcumin 5.0616631530 19188055
MESH:D013276 Stomach Ulcer Plant Extracts 5.0615255614 12787963 18237397 17135157 18193104
MESH:D020521 Stroke Folic Acid 3.5916517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.6816321402
MESH:D013345 Subarachnoid Hemorrhage pifithrin 5.1518364113
MESH:D013398 Sudden Infant Death Oxygen 4.6512563064
MESH:D015173 Supratentorial Neoplasms Vincristine 4.9812837982
MESH:D013576 Syndactyly Methotrexate 4.189562676
MESH:D024801 Tauopathies Camptothecin 8.8716930453
MESH:D024801 Tauopathies Paclitaxel 8.8716930453
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 4.5717997062
MESH:D013736 Testicular Neoplasms Cisplatin 3.7917225452 15464296
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.7811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.3815669648
MESH:D013953 Thymus Neoplasms Benzene 9.2310850423
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 9.2315790496
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 2.9912697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 18.761399818 3712494 6587162 6582329 7505956
MESH:D013964 Thyroid Neoplasms arsenic trioxide 18.7619014326
MESH:D013964 Thyroid Neoplasms decitabine 18.7617967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 18.767505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 18.7616010429 17909728
MESH:D013964 Thyroid Neoplasms Phenobarbital 18.761399818
MESH:D013978 Tibial Fractures Estradiol 3.7719048282
MESH:D014062 Tongue Neoplasms Fluorouracil 12.0516280240
MESH:D014062 Tongue Neoplasms resveratrol 12.0516227395
MESH:D014062 Tongue Neoplasms Zinc 12.0516543248
MESH:D016171 Torsades de Pointes arsenic trioxide 3.0715213294
MESH:D014402 Tuberous Sclerosis Sirolimus 4.7118495876 21115397
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 55.2616049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 55.2616049721
MESH:D001749 Urinary Bladder Neoplasms 2-Acetylaminofluorene 55.2615867355 1399818 15289314
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 55.268074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 55.2611780464 20435036 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 55.2617053015
MESH:D001749 Urinary Bladder Neoplasms Cacodylic Acid 55.2615537745
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 55.2612973940 15464296 17225452
MESH:D001749 Urinary Bladder Neoplasms Curcumin 55.2618593936
MESH:D001749 Urinary Bladder Neoplasms decitabine 55.2617616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 55.2616712894 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 55.2617653716
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 55.2616720286
MESH:D001749 Urinary Bladder Neoplasms Quercetin 55.2616720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 55.2611723127 16712894 17306315 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 55.2616712894 8653321 17572228
MESH:D001749 Urinary Bladder Neoplasms Vehicle Emissions 55.2611144890
MESH:D014565 Urogenital Neoplasms Curcumin 4.3718462866
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 9.0210091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 9.0210091137
MESH:D014581 Urticaria Acetaminophen 2.1610982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 26.6716803524
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 26.6716175088
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 26.6716154183
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 26.6716803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 26.6717473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 26.6711813266
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.2614652134
MESH:D014594 Uterine Neoplasms Benzene 15.9712562636
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 15.9715809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 15.9714692618
MESH:D014594 Uterine Neoplasms resveratrol 15.9717044934
MESH:D014604 Uveal Neoplasms decitabine 4.0017785578
MESH:D014605 Uveitis Cyclosporine 9.051336536
MESH:D014605 Uveitis Sirolimus 9.051336536
MESH:D014625 Vaginal Neoplasms Cisplatin 13.4715577323
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 13.4716002989 16513791
MESH:D014625 Vaginal Neoplasms Zidovudine 13.4712579204
MESH:D014652 Vascular Diseases sodium arsenite 3.5317056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.6812125929
MESH:D019043 Vascular Neoplasms Urethane 5.0010620525
MESH:D020301 Vasospasm, Intracranial pifithrin 4.7218364113
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.7214671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 12.2117334414 16364871 17678736 17638931
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 12.2118097624
MESH:D018487 Ventricular Dysfunction, Left resveratrol 12.2117488730
MESH:D020257 Ventricular Remodeling Plant Extracts 4.4218097624
MESH:D014839 Vomiting Cisplatin 3.8111897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.3315886252
MESH:D014947 Wounds and Injuries Plant Extracts 3.5020213670 19894650
MESH:D014985 Xerophthalmia Cyclosporine 3.5317120751
Pathway ID Pathway Name
KEGG:05219 Bladder cancer
KEGG:04110 Cell cycle
REACT:1538 Cell Cycle Checkpoints
KEGG:05220 Chronic myeloid leukemia
KEGG:04144 Endocytosis
KEGG:05214 Glioma
KEGG:05218 Melanoma
KEGG:04115 p53 signaling pathway
KEGG:05200 Pathways in cancer
KEGG:05215 Prostate cancer
REACT:11061 Signalling by NGF
REACT:13685 Synaptic Transmission
KEGG:04120 Ubiquitin mediated proteolysis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA30718
    • Releated gene ID Related gene Name
    PA36679TP53
    Releated disease ID Related disease Name
    PA443622Carcinoma, Non-Small-Cell Lung
    PA443560Breast Neoplasms
    PA444283Glioblastoma
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    PA445742Stomach Neoplasms
    Releated drug ID Related drug Name
    PA449014cisplatin
    PA164712331Alkylating Agents
    PA150481186topoisomerase I inhibitors
    PA164712535Beta Blocking Agents
    PA449957ibuprofen
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB02872 - Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone
    DB04144 - Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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