AutismKB 2.0

Annotation Detail for ME1


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Basic Information Top
Gene Symbol:ME1 ( HUMNDME,MES )
Gene Full Name: malic enzyme 1, NADP(+)-dependent, cytosolic
Band: 6q14.2
Quick LinksEntrez ID:4199; OMIM: 154250; Uniprot ID:MAOX_HUMAN; ENSEMBL ID: ENSG00000065833; HGNC ID: 6983
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
GLUCONEO-PWYgluconeogenesis I
Pathway IDPathway Name
hsa03320PPAR signaling pathway
hsa01100Metabolic pathways
hsa00620Pyruvate metabolism
Pathway IDPathway Name
Metabolism of lipids and lipoproteins
No data
Pathway IDPathway Name
P02772Pyruvate metabolism
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of ME1 mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane affects the expression of ME1 mRNAaffects expression 18648102
C016601 4-hydroxytamoxifen 4-hydroxytamoxifen results in increased expression of ME1 mRNAincreases expression 19901195
C029728 4-phenylenediamine 4-phenylenediamine results in increased expression of ME1 mRNAincreases expression 16314067
D000082 Acetaminophen Acetaminophen affects the expression of ME1 mRNAaffects expression 17562736
15606129
D000082 Acetaminophen Acetaminophen results in increased expression of ME1 proteinincreases expression 16538043
16687475
D013196 Dihydrotestosterone Dihydrotestosterone results in increased expression of ME1 mRNAincreases expression 16631469
C040534 alpha-hexachlorocyclohexane alpha-hexachlorocyclohexane results in increased expression of ME1 mRNAincreases expression 17785943
D000638 Amiodarone Amiodarone affects the expression of ME1 mRNAaffects expression 19483382
D000638 Amiodarone Amiodarone results in increased expression of ME1 proteinincreases expression 16538043
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ME1 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of ME1 mRNAincreases expression 20458559
19417148
15725085
D001553 Benzbromarone Benzbromarone affects the expression of ME1 mRNAaffects expression 19483382
D001554 Benzene Benzene affects the expression of ME1 mRNAaffects expression 15878777
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of ME1 mRNAincreases expression 20127859
C095105 bexarotene bexarotene results in increased expression of ME1 mRNAincreases expression 16648578
C002791 bismuth tripotassium dicitrate bismuth tripotassium dicitrate results in decreased expression of ME1 mRNAdecreases expression 15912405
C006780 bisphenol A bisphenol A affects the expression of ME1 mRNAaffects expression 20170705
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of ME1 mRNAincreases expression 12414654
15336504
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ME1 mRNAaffects cotreatment|decreases expression 20360939
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of ME1 proteinincreases expression 16538043
C503589 cis-9, trans-11-conjugated linoleic acid cis-9, trans-11-conjugated linoleic acid results in increased expression of ME1 mRNAincreases expression 17217560
D002994 Clofibrate PPARA protein affects the reaction [Clofibrate results in increased expression of ME1 mRNA]affects reaction|increases expression 17585979
D002994 Clofibrate Clofibrate affects the expression of ME1 mRNAaffects expression 19483382
D003345 Corticosterone Corticosterone results in decreased expression of ME1 mRNAdecreases expression 15755911
D018119 Stavudine [Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNAaffects cotreatment|increases expression 11741158
D018119 Stavudine [Stavudine co-treated with Lamivudine co-treated with Nelfinavir] results in decreased expression of ME1 mRNAaffects cotreatment|decreases expression 11741158
D018119 Stavudine [Stavudine co-treated with Lamivudine] results in increased expression of ME1 mRNAaffects cotreatment|increases expression 11741158
D018119 Stavudine Stavudine results in increased expression of ME1 mRNAincreases expression 11741158
C004742 daidzein daidzein results in increased expression of ME1 mRNAincreases expression 16865672
D019259 Lamivudine Lamivudine results in increased expression of ME1 mRNAincreases expression 11741158
D019259 Lamivudine [Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNAaffects cotreatment|increases expression 11741158
D019259 Lamivudine [Stavudine co-treated with Lamivudine co-treated with Nelfinavir] results in decreased expression of ME1 mRNAaffects cotreatment|decreases expression 11741158
D019259 Lamivudine [Stavudine co-treated with Lamivudine] results in increased expression of ME1 mRNAaffects cotreatment|increases expression 11741158
D019259 Lamivudine [Zidovudine co-treated with Lamivudine] affects the expression of ME1 mRNAaffects cotreatment|affects expression 11741158
D019259 Lamivudine [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNAaffects cotreatment|increases expression 11741158
D004041 Dietary Fats Dietary Fats results in increased expression of ME1 mRNAincreases expression 16357043
18457598
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ME1 mRNAaffects cotreatment|decreases expression 20360939
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNAaffects cotreatment|increases expression 20033131
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of ME1 mRNAincreases expression 19638242
D004052 Diethylnitrosamine isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA]affects cotreatment|decreases reaction|increases expression 20033131
D004052 Diethylnitrosamine Melatonin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA]affects cotreatment|decreases reaction|increases expression 20033131
D004052 Diethylnitrosamine [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of ME1 mRNAaffects cotreatment|increases expression 18754104
D004178 Diquat Diquat results in increased expression of ME1 mRNAincreases expression 16962985
C007610 equol equol results in increased expression of ME1 mRNAincreases expression 16865672
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of ME1 mRNAaffects cotreatment|increases expression 19619570
D004958 Estradiol Estradiol results in increased expression of ME1 mRNAincreases expression 19619570
D000431 Ethanol [Fish Oils co-treated with Ethanol] results in increased expression of ME1 mRNAaffects cotreatment|increases expression 17347304
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ME1 mRNAaffects expression 20170705
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ME1 mRNAaffects expression 20170705
D005001 Ethionine Ethionine affects the expression of ME1 mRNAaffects expression 19483382
D005395 Fish Oils [Fish Oils co-treated with Ethanol] results in increased expression of ME1 mRNAaffects cotreatment|increases expression 17347304
C106014 gedunin gedunin results in increased expression of ME1 mRNAincreases expression 17010675
D019833 Genistein Genistein results in increased expression of ME1 mRNAincreases expression 16865672
D005978 Glutathione Glutathione deficiency results in increased expression of ME1 mRNAincreases expression 15345336
C071834 glycidamide glycidamide results in increased expression of ME1 mRNAincreases expression 17822822
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of ME1 mRNAincreases expression 12414654
D019469 Indinavir [Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNAaffects cotreatment|increases expression 11741158
D019469 Indinavir [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNAaffects cotreatment|increases expression 11741158
D007213 Indomethacin Indomethacin results in increased expression of ME1 mRNAincreases expression 18299717
D007501 Iron Iron deficiency results in increased expression of ME1 mRNAincreases expression 20368581
D007529 Isoflavones Isoflavones results in increased expression of ME1 mRNAincreases expression 17374662
C016527 isoquercitrin isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA]affects cotreatment|decreases reaction|increases expression 20033131
C095104 LG 100268 LG 100268 results in increased expression of ME1 mRNAincreases expression 16489205
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of ME1 mRNAdecreases expression 12388159
C030298 malic acid ME1 protein results in decreased carboxylation of malic aciddecreases carboxylation 16865672
D008550 Melatonin Melatonin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA]affects cotreatment|decreases reaction|increases expression 20033131
D008770 Methylnitrosourea Methylnitrosourea results in increased expression of ME1 mRNAincreases expression 16525678
C008493 methylselenic acid methylselenic acid results in increased expression of ME1 mRNAincreases expression 18548127
D019888 Nelfinavir Nelfinavir results in decreased expression of ME1 mRNAdecreases expression 11741158
D019888 Nelfinavir [Stavudine co-treated with Lamivudine co-treated with Nelfinavir] results in decreased expression of ME1 mRNAaffects cotreatment|decreases expression 11741158
C029938 nickel sulfate nickel sulfate results in increased expression of ME1 mRNAincreases expression 16314067
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of ME1 mRNAincreases expression 17616710
C025589 ochratoxin A ochratoxin A results in decreased expression of ME1 mRNAdecreases expression 16251485
D009853 Omeprazole Omeprazole affects the expression of ME1 mRNAaffects expression 19483382
C011030 oxfendazole [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNAaffects cotreatment|increases expression 20033131
C011030 oxfendazole isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA]affects cotreatment|decreases reaction|increases expression 20033131
C011030 oxfendazole Melatonin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of ME1 mRNA]affects cotreatment|decreases reaction|increases expression 20033131
C011030 oxfendazole [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of ME1 mRNAaffects cotreatment|increases expression 18754104
D010126 Ozone Ozone results in decreased expression of ME1 mRNAdecreases expression 16183385
C023036 perfluorooctanoic acid perfluorooctanoic acid affects the expression of ME1 mRNAaffects expression 18281256
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of ME1 mRNAincreases expression 17681415
C023036 perfluorooctanoic acid perfluorooctanoic acid affects the expression of ME1 mRNAaffects expression 17383973
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased expression of ME1 mRNAincreases expression 16221955
D010795 Phthalic Acids Phthalic Acids results in decreased expression of ME1 mRNAdecreases expression 15728792
D010882 Piperonyl Butoxide Piperonyl Butoxide results in increased expression of ME1 mRNAincreases expression 18544911
D010882 Piperonyl Butoxide Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of ME1 mRNA]increases expression|increases reaction 18544911
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ME1 mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of ME1 mRNAincreases expression 17426115
15777286
20059764
16357043
16489205
C006253 pirinixic acid pirinixic acid results in increased expression of ME1 proteinincreases expression 15226431
C006253 pirinixic acid PPARA protein affects the reaction [pirinixic acid results in increased expression of ME1 mRNA]affects reaction|increases expression 16489205
15777286
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of ME1 mRNA]increases expression|increases reaction 20059764
C006253 pirinixic acid pirinixic acid affects the expression of ME1 mRNAaffects expression 19483382
C006253 pirinixic acid pirinixic acid results in increased expression of ME1 mRNAincreases expression 16489205
C025299 polyphenols polyphenols results in decreased expression of ME1 mRNAdecreases expression 16293270
C035988 procymidone procymidone results in decreased expression of ME1 mRNAdecreases expression 15686871
D011441 Propylthiouracil Propylthiouracil affects the expression of ME1 mRNAaffects expression 19483382
C052785 rebamipide rebamipide results in increased expression of ME1 mRNAincreases expression 18299717
C488333 Ro 65-7199 Ro 65-7199 results in increased expression of ME1 mRNAincreases expression 14610520
C488334 Ro 66-0074 Ro 66-0074 results in increased expression of ME1 mRNAincreases expression 14610520
D019258 Saquinavir Saquinavir results in decreased expression of ME1 mRNAdecreases expression 11741158
C515055 S-(dimethylarsino)-glutathione S-(dimethylarsino)-glutathione results in increased expression of ME1 mRNAincreases expression 19417148
D012643 Selenium Selenium results in decreased expression of ME1 mRNAdecreases expression 19244175
C446685 systhane systhane affects the expression of ME1 mRNAaffects expression 17383973
D014284 Triiodothyronine Triiodothyronine results in increased expression of ME1 mRNAincreases expression 15953391
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of ME1 mRNAaffects cotreatment|increases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of ME1 mRNAincreases expression 17555868
19619570
19901195
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of ME1 mRNAincreases expression 16054898
18465118
D013752 Tetracycline Tetracycline results in increased expression of ME1 proteinincreases expression 16538043
D013853 Thioacetamide Thioacetamide affects the expression of ME1 mRNAaffects expression 19483382
C052342 topiramate topiramate results in decreased expression of ME1 mRNAdecreases expression 16979414
C496197 trans-10,cis-12-conjugated linoleic acid trans-10,cis-12-conjugated linoleic acid results in increased expression of ME1 mRNAincreases expression 17217560
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of ME1 mRNAincreases expression 17982090
C050414 tripterine tripterine results in increased expression of ME1 mRNAincreases expression 17010675
D014315 Triterpenes Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of ME1 mRNA]increases expression|increases reaction 18544911
D014807 Vitamin D Vitamin D affects the expression of ME1 mRNAaffects expression 20368581
D024483 Vitamin K 3 Vitamin K 3 results in increased expression of ME1 mRNAincreases expression 12414654
D015215 Zidovudine [Zidovudine co-treated with Lamivudine] affects the expression of ME1 mRNAaffects cotreatment|affects expression 11741158
D015215 Zidovudine [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNAaffects cotreatment|increases expression 11741158
D015215 Zidovudine Zidovudine results in decreased expression of ME1 mRNAdecreases expression 11741158
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 5.9318926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 5.9311752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 7.9018287403
MESH:D000138 Acidosis Ethanol 7.9011192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.1517505938
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 4.079612607
MESH:D055371 Acute Lung Injury Lipopolysaccharides 11.1711850527 18653653
MESH:D055371 Acute Lung Injury nickel sulfate 11.1711954676 16100012 19131640 12718980
MESH:D055371 Acute Lung Injury pirinixic acid 11.1718653653
MESH:D000230 Adenocarcinoma arsenic trioxide 19.7619825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 19.7620127859 20464547
MESH:D000230 Adenocarcinoma daidzein 19.7611473722
MESH:D000230 Adenocarcinoma Estradiol 19.7611473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 19.7614692618
MESH:D000230 Adenocarcinoma Genistein 19.7611473722
MESH:D000230 Adenocarcinoma Indomethacin 19.7616537180
MESH:D000230 Adenocarcinoma Methylnitrosourea 19.7615688392 15113128
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 15.643712494
MESH:D000236 Adenoma Benzo(a)pyrene 15.646695378
MESH:D000236 Adenoma Diethylnitrosamine 15.646695378 10737359
MESH:D000236 Adenoma Indomethacin 15.6411497255
MESH:D000236 Adenoma Melatonin 15.6417195641
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 12.8219061943 17162532 19052882 16434500 17620307 18056438
MESH:D018248 Adenoma, Liver Cell pirinixic acid 12.8216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 12.8216835633
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.5315451039 15451040
MESH:D000437 Alcoholism topiramate 4.4018552399 17925516 19331489
MESH:D000505 Alopecia Isoflavones 4.0817569567
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 4.8716640825
MESH:D016301 Alveolar Bone Loss Indomethacin 4.5817225004
MESH:D000544 Alzheimer Disease Indomethacin 5.2817627676 15579461
MESH:D000544 Alzheimer Disease Iron 5.2816563566 16640825
MESH:D000544 Alzheimer Disease Ozone 5.2815513908
MESH:D000740 Anemia Iron 6.6516434484 16566752
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.6511748828
MESH:D000741 Anemia, Aplastic Benzene 3.7414761424 11369114 17661222
MESH:D018798 Anemia, Iron-Deficiency Iron 3.9617162259 17375513 16569441 17147795 17163184
MESH:D000756 Anemia, Sideroblastic Iron 4.1116910769
MESH:D000799 Angioedema Acetaminophen 3.0510982225
MESH:D000853 Anophthalmos Ethanol 4.0615513904
MESH:D001008 Anxiety Disorders Ethanol 3.3711141031
MESH:D001014 Aortic Aneurysm Indomethacin 4.1110231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 9.1919183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 9.1910388637
MESH:D001145 Arrhythmias, Cardiac Amiodarone 6.9718218290 20041841 18057881
MESH:D001145 Arrhythmias, Cardiac Iron 6.9716604332
MESH:D001161 Arteriosclerosis Dietary Fats 7.4015238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 7.4011256880
MESH:D018771 Arthralgia Indomethacin 4.382160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.1415885639
MESH:D001172 Arthritis, Rheumatoid Indomethacin 4.0011248219
MESH:D001172 Arthritis, Rheumatoid Ozone 4.0015570426
MESH:D001249 Asthma Ozone 2.3517854713 16373670
MESH:D001260 Ataxia Telangiectasia Iron 4.6715336622
MESH:D050197 Atherosclerosis Iron 3.2116640825 16632123
MESH:D001281 Atrial Fibrillation Amiodarone 3.2918651412 19698954
MESH:D001289 Attention Deficit Disorder with Hyperactivity Phthalic Acids 3.8020106747
MESH:D001321 Autistic Disorder Acetaminophen 2.3918445737
MESH:D001321 Autistic Disorder Glutathione 2.3919056591 16917939 19267885 18929414
MESH:D001321 Autistic Disorder Iron 2.3917352947
MESH:D001321 Autistic Disorder Melatonin 2.3916897403 16919138
MESH:D001424 Bacterial Infections Iron 4.4216640825
MESH:D001477 Bartter Syndrome Indomethacin 4.2210684365
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.2311289319 1440618
MESH:D001778 Blood Coagulation Disorders Amiodarone 50.6919483382
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 50.6916206674
MESH:D001778 Blood Coagulation Disorders Benzbromarone 50.6919483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 50.6919483382
MESH:D001778 Blood Coagulation Disorders Ethionine 50.6919483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 50.6919483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 50.6919483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 50.6919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 50.6912125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 50.6919483382
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.0015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.2215746008
MESH:D001855 Bone Marrow Diseases Benzene 4.4416183116
MESH:D001862 Bone Resorption bisphenol A 3.1611985600
MESH:D001929 Brain Edema Indomethacin 4.2311481608
MESH:D002545 Brain Ischemia Indomethacin 3.6512524144
MESH:D001943 Breast Neoplasms Benzene 10.4311921183 17162533
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 10.4317474063 20146248
MESH:D001943 Breast Neoplasms bexarotene 10.4316344269 16818667
MESH:D001943 Breast Neoplasms bisphenol A 10.4317123778
MESH:D001943 Breast Neoplasms Dietary Fats 10.4320435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 10.4317474063
MESH:D001943 Breast Neoplasms equol 10.4316898868
MESH:D001943 Breast Neoplasms Estradiol 10.4312948864 19861407 17289903 18497071 17261762 14630087 17018787 16675129
MESH:D001943 Breast Neoplasms Genistein 10.4316873071 17200150 16541309
MESH:D001943 Breast Neoplasms Indomethacin 10.4317401462
MESH:D001943 Breast Neoplasms LG 100268 10.4316818667
MESH:D001943 Breast Neoplasms Methylnitrosourea 10.4314633655 16253758 11306469
MESH:D001943 Breast Neoplasms ochratoxin A 10.4311921183
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 10.4320435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.0517626835 16777450 18315731 14754758 18417511 19059883 15516495
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.6011589617
MESH:D002056 Burns Ethanol 8.8616374292
MESH:D002056 Burns Indomethacin 8.8610459503
MESH:D002100 Cachexia Indomethacin 9.8216537180 11239499 15625704 15141370
MESH:D002100 Cachexia Ozone 9.8216183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.6916111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 7.933786805 16227642 10355542 15721981 16050911 15700767 16097048 15673190 16124888 16011737 18705752 16192424
MESH:D002252 Carbon Tetrachloride Poisoning Melatonin 7.9315700767
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.1716835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 24.0916705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 24.093581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 24.093084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 24.0915073043 14691202 15553829 16217749 11135700
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 24.091701930
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 24.0918788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 24.0920101231 19919837 19383236 20727157 20524982 18788625 11831363 18056438 10737359 16328049 20084675 16681979 16830150 16502159 16288022 18691550 17428255 18494052 19822196 17162532 18978308 19208518 18506893 17055752 19519916 17761372 19171122 19701751 19107877 19539802 19335982 20514400 21159647 16878318 19394651 3084413 17138121 20432363 17978847 18210153 20935162 20214788 20007298 16935385 16540662 19052882 18971187 10672840 16807293 18393292 3581430 16569478 16779866 19418558 17173139 20512989 16698587 18785209 18665156
MESH:D006528 Carcinoma, Hepatocellular Estradiol 24.0916924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 24.0918788625 15763234 15289165
MESH:D006528 Carcinoma, Hepatocellular Genistein 24.0916924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 24.0916391822
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 24.0917997003
MESH:D002278 Carcinoma in Situ bisphenol A 4.2117123778
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 3.9511053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.5718791128 14736730 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 2.9016247446
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.0819014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 5.177296757
MESH:D002292 Carcinoma, Renal Cell Indomethacin 5.1717341418
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.4312490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 5.9120419170
MESH:D002294 Carcinoma, Squamous Cell Glutathione 5.9117015178
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 5.9112636206 15482327
MESH:D006332 Cardiomegaly Ethanol 5.2019332462
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.2018850075 18670907 16120746
MESH:D009202 Cardiomyopathies Iron 3.4916640825
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 5.0115710769 19225199
MESH:D002311 Cardiomyopathy, Dilated Iron 5.0116604332
MESH:D002318 Cardiovascular Diseases daidzein 12.7116332659
MESH:D002318 Cardiovascular Diseases Genistein 12.7116332659
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 12.7116936243
MESH:D002318 Cardiovascular Diseases Isoflavones 12.7117689850
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.3118974383
MESH:D002386 Cataract Acetaminophen 5.8410977129
MESH:D002386 Cataract Methylnitrosourea 5.8412484553
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 15.057505956
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 15.051399818
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 15.0521159647 17174075 7505956 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 15.0518566989
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 15.052727394 7505956
MESH:D002637 Chest Pain Omeprazole 4.3215447763
MESH:D002659 Child Development Disorders, Pervasive topiramate 3.7515650499
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 12.2519052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 12.2516835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 12.2518291259
MESH:D002764 Cholecystitis Indomethacin 4.3811181007
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 9.8619486331 9022650
MESH:D002779 Cholestasis Ethinyl Estradiol 9.8611677210 17681005 17333356 16105132 15861022 16919318 17110522
MESH:D002779 Cholestasis pirinixic acid 9.8619176532
MESH:D002971 Cleft Lip Ethanol 3.1215513904
MESH:D002972 Cleft Palate Ethanol 4.6115513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 4.6116354765 8697196 12621046 15668235 15340226
MESH:D003092 Colitis Selenium 7.3017936198
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 7.3018023891 16804969 16867261 11698051 17936198 16782535 17991707 16474422 18200517
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 3.1117276891
MESH:D003110 Colonic Neoplasms Genistein 6.5317182828
MESH:D003110 Colonic Neoplasms Indomethacin 6.5315936596 15625704 11260862 15786552 15963497 15637740
MESH:D003110 Colonic Neoplasms Iron 6.5316640825
MESH:D003110 Colonic Neoplasms polyphenols 6.5316293270
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.0220501625
MESH:D015179 Colorectal Neoplasms Indomethacin 3.0217054584 12606626 11197048 18059344
MESH:D015179 Colorectal Neoplasms Isoflavones 3.0217116718
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.3914669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.4412609071
MESH:D018352 Coronavirus Infections Indomethacin 4.9217302372
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 5.8710525206
MESH:D019465 Craniofacial Abnormalities Benzene 5.8715643154
MESH:D019465 Craniofacial Abnormalities Ethanol 5.8715513904 19302082 15451040 15451039 11873399 10194807 11198716
MESH:D019465 Craniofacial Abnormalities ochratoxin A 5.8720036863
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 5.8710048152 15322242 20055451
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.2618551238
MESH:D003550 Cystic Fibrosis Glutathione 3.8119747007
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.3715213294
MESH:D003872 Dermatitis Benzene 4.0115902427
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 7.5812868966 11298694 8156756 14531868 2524372 8970840 18759878 11906362
MESH:D017449 Dermatitis, Allergic Contact 4-phenylenediamine 7.5811906362 16533241 16823706 11298694 18759875 19470301
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 7.5816780908 11298694 16823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.0018249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 7.413621924 2952479
MESH:D003877 Dermatitis, Contact 4-phenylenediamine 7.4111531941
MESH:D003920 Diabetes Mellitus Iron 3.7916604332 16640825
MESH:D003922 Diabetes Mellitus, Type 1 Iron 3.0616506275
MESH:D003924 Diabetes Mellitus, Type 2 daidzein 13.6216647724
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 13.6220387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 13.6216647724
MESH:D003924 Diabetes Mellitus, Type 2 Iron 13.6216506275
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 13.6217107852
MESH:D003924 Diabetes Mellitus, Type 2 topiramate 13.6216979414
MESH:D003928 Diabetic Nephropathies Estradiol 2.7519279558
MESH:D003967 Diarrhea Indomethacin 3.087237001 7907874
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 32.4618551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 32.4618289764 16192314 1440618 9653073 18648102 7440962 6679447 18692083 9328219 6482804 11289319 9022650 8291058
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 32.4614550746 14986274 12392966 11461765 17562736 12958197 11739529 16177239 10663392 10915739 19370779 16109766 16393943 11834606 19164858 16227642 12594235 17522070 11743745 15968718 2444490 19420014 12705907 11421492 19923254 16081117 11529661 19085960 12540782 14725611 12153990 17906064 18713872 19416960 16781746 19739265 16485898 18071297 15619225 11287661 10774834
MESH:D056486 Drug-Induced Liver Injury Amiodarone 32.4615265979 18218290
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 32.469327722 11566570 21278145 16177239 4309450 7120509 15027814 3732212 17522070 6884620 10092053 7179309 2869522 15998439 10915739 3786805 15968718 19336974 7440962 6623471 19085960 16227642
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 32.4619107877
MESH:D056486 Drug-Induced Liver Injury Diquat 32.4618164269 18445702
MESH:D056486 Drug-Induced Liver Injury Ethanol 32.4611566570
MESH:D056486 Drug-Induced Liver Injury polyphenols 32.4619370779
MESH:D056486 Drug-Induced Liver Injury Selenium 32.4615131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 32.4620420201
MESH:D056486 Drug-Induced Liver Injury Tetracycline 32.4617522070
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 32.4612963478
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.3119426721
MESH:D004362 Drug Toxicity Lamivudine 14.7615040536
MESH:D004362 Drug Toxicity Stavudine 14.7615040536
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 14.7611462148
MESH:D004362 Drug Toxicity Zidovudine 14.7615040536
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.3716326151 18446180 12774134 18043480 16133044 17190690
MESH:D004381 Duodenal Ulcer Indomethacin 7.0811535926 11595415 17151854 10671773 17329845 17045617 17351913 11595431 16699067 17202747 11991626
MESH:D004381 Duodenal Ulcer Omeprazole 7.0817151854 16613094 15991576 21218061
MESH:D050171 Dyslipidemias Clofibrate 6.8416707586
MESH:D050171 Dyslipidemias Dietary Fats 6.8418367378
MESH:D004487 Edema Indomethacin 10.817907874 10653021 16100529 19703484 8273558 8985016 7990266
MESH:D004487 Edema perfluorooctanoic acid 10.8117259670 12083418
MESH:D004487 Edema pirinixic acid 10.8112083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.8112711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.1115322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 2.4612538720
MESH:D004714 Endometrial Hyperplasia Genistein 3.8116402032
MESH:D016889 Endometrial Neoplasms 4-hydroxytamoxifen 13.3419148513
MESH:D016889 Endometrial Neoplasms daidzein 13.3411473722
MESH:D016889 Endometrial Neoplasms Estradiol 13.3418566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Genistein 13.3411473722
MESH:D004715 Endometriosis Indomethacin 6.7915652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 6.7910568697 9294722
MESH:D019446 Endotoxemia Indomethacin 8.0818509659
MESH:D019446 Endotoxemia Lipopolysaccharides 8.0815821434 15328337 17637181
MESH:D004751 Enteritis Indomethacin 3.9616328016 10567023 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.2217980183
MESH:D004802 Eosinophilia Indomethacin 3.3111298111
MESH:D004827 Epilepsy topiramate 3.8719148780
MESH:D004833 Epilepsy, Temporal Lobe topiramate 5.4816499746
MESH:D007172 Erectile Dysfunction daidzein 4.2814972507
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.3216302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 13.733581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 13.7312903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 13.7316530937
MESH:D004938 Esophageal Neoplasms Ethanol 13.7316704527
MESH:D004938 Esophageal Neoplasms Indomethacin 13.7311005569
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 13.7315623463 15264214 16805852 15547733 16704527 15878914 15150132 16510608 15547721
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.4011564622
MESH:D005218 Fat Necrosis Thioacetamide 4.9316456712
MESH:D005234 Fatty Liver Amiodarone 62.8714986274
MESH:D005234 Fatty Liver arsenic trioxide 62.8715073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 62.8712795759 16239168 12631006 16045604 19224547 17595544 61145 15959796
MESH:D005234 Fatty Liver Clofibrate 62.8719224547
MESH:D005234 Fatty Liver Dietary Fats 62.8719004024 18296743 19551842 17967931
MESH:D005234 Fatty Liver Diethylnitrosamine 62.8721071580 20387270
MESH:D005234 Fatty Liver Ethanol 62.8718620774 19236843 16409862
MESH:D005234 Fatty Liver Ethinyl Estradiol 62.8715345470
MESH:D005234 Fatty Liver Fish Oils 62.8718620774
MESH:D005234 Fatty Liver Iron 62.8716640825
MESH:D005234 Fatty Liver pirinixic acid 62.8720131406 19236843
MESH:D005234 Fatty Liver Stavudine 62.8718299183
MESH:D005234 Fatty Liver Tetracycline 62.8716917069 19224547
MESH:D005234 Fatty Liver Zidovudine 62.8718299183
MESH:D005235 Fatty Liver, Alcoholic Ethanol 4.8717920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.5215451040 16946407 10194807 15513904
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.7011858732
MESH:D005334 Fever Indomethacin 7.0811852909 10431976 17627676
MESH:D005334 Fever Lipopolysaccharides 7.0811852909 9205823
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.236705139
MESH:D005354 Fibrosarcoma Indomethacin 9.6310962813
MESH:D005354 Fibrosarcoma Methylnitrosourea 9.6311555667
MESH:D005355 Fibrosis Carbon Tetrachloride 19.8218705752
MESH:D005355 Fibrosis Dietary Fats 19.8218296743
MESH:D005355 Fibrosis Indomethacin 19.8217994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 19.8220067830
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 19.8217994277
MESH:D005499 Folliculitis Indomethacin 4.3811298111
MESH:D005621 Friedreich Ataxia Iron 4.6716640825 16604332
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.5216904648
MESH:D005756 Gastritis Acetaminophen 20.9216983495
MESH:D005756 Gastritis Diquat 20.9215046732
MESH:D005756 Gastritis Ethanol 20.9215046732
MESH:D005756 Gastritis Indomethacin 20.9215046732
MESH:D005909 Glioblastoma Genistein 5.5816598420
MESH:D005909 Glioblastoma Indomethacin 5.5812870263
MESH:D005910 Glioma Indomethacin 5.2216487511 18371953
MESH:D005910 Glioma Methylnitrosourea 5.229825942
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.6411849393
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.317505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.8010696789
MESH:D006073 Gout Indomethacin 4.5711248219
MESH:D006258 Head and Neck Neoplasms Indomethacin 3.1815482327
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 4.8620471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 4.8611294989 10048152
MESH:D006333 Heart Failure pirinixic acid 5.1820558911
MESH:D006333 Heart Failure Selenium 5.1817162251
MESH:D006402 Hematologic Diseases Benzene 8.6816183116
MESH:D006402 Hematologic Diseases Zidovudine 8.6812579204
MESH:D006432 Hemochromatosis Iron 3.8916574947 17236123 16640825 16604332 17053826 17255318
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.6916366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.6311000095
MESH:D006486 Hemosiderosis Iron 4.4216604332
MESH:D006501 Hepatic Encephalopathy Indomethacin 8.5915633222
MESH:D006501 Hepatic Encephalopathy Thioacetamide 8.5918665440 15929193 17276928
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 11.476705139
MESH:D006505 Hepatitis Carbon Tetrachloride 11.4719110552 19900420
MESH:D006505 Hepatitis Thioacetamide 11.4716456712
MESH:D006509 Hepatitis B Lamivudine 4.3917703166
MESH:D019694 Hepatitis B, Chronic Lamivudine 4.3915309715 15631357 15274664 16476009 12044531
MESH:D019698 Hepatitis C, Chronic Indomethacin 3.9415135802
MESH:D006525 Hepatitis, Viral, Human Iron 4.6816640825
MESH:D006527 Hepatolenticular Degeneration Iron 4.1817182432
MESH:D006529 Hepatomegaly Amiodarone 24.0815265979
MESH:D006529 Hepatomegaly Iron 24.0816890145
MESH:D006529 Hepatomegaly perfluorooctanoic acid 24.083609246
MESH:D006529 Hepatomegaly pirinixic acid 24.0819176532 16221962 19772884 18467677
MESH:D006529 Hepatomegaly systhane 24.0817178688 17178689
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 24.0812621046 15340226 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.2415709030
MESH:D015658 HIV Infections Indinavir 23.1915388451 11141242 11363243
MESH:D015658 HIV Infections Iron 23.1916597321
MESH:D015658 HIV Infections Lamivudine 23.1917530837 9296927 11141242 20032539
MESH:D015658 HIV Infections Nelfinavir 23.1915388451 11362904
MESH:D015658 HIV Infections Saquinavir 23.1915388451 11141242
MESH:D015658 HIV Infections Stavudine 23.1911141242
MESH:D015658 HIV Infections Zidovudine 23.1911141242 11698656 17358032 20032539 11363243
MESH:D019584 Hot Flashes Estradiol 7.8117088409
MESH:D019584 Hot Flashes Isoflavones 7.8114716179 17290160
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.2518606429 8697196 16959395 15340226 16354765
MESH:D006930 Hyperalgesia Acetaminophen 13.5316870215
MESH:D006930 Hyperalgesia Ethanol 13.5318783367
MESH:D006930 Hyperalgesia Indomethacin 13.5312727271
MESH:D006930 Hyperalgesia perfluorooctanoic acid 13.5312083418
MESH:D034321 Hyperamylasemia Indomethacin 4.9217883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.7516899240
MESH:D006937 Hypercholesterolemia Amiodarone 6.848137927 9751232
MESH:D006937 Hypercholesterolemia Dietary Fats 6.8421332399
MESH:D006940 Hyperemia Indomethacin 4.2312524144
MESH:D006943 Hyperglycemia pirinixic acid 2.5020558911
MESH:D006949 Hyperlipidemias Dietary Fats 11.4621332399
MESH:D006949 Hyperlipidemias Fish Oils 11.4615752949
MESH:D006949 Hyperlipidemias Indomethacin 11.4617546600
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.1815034207
MESH:D006968 Hypersensitivity, Delayed Fish Oils 4.7211484837
MESH:D006973 Hypertension Benzene 6.6317940673
MESH:D006973 Hypertension daidzein 6.6317169123
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 6.6318850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.3315338365
MESH:D007006 Hypogonadism Iron 3.8216640825
MESH:D007021 Hypospadias Ethinyl Estradiol 3.0516945680 16569931
MESH:D007037 Hypothyroidism Amiodarone 15.1318020914 17991464
MESH:D007037 Hypothyroidism Iron 15.1316640825
MESH:D007037 Hypothyroidism Propylthiouracil 15.138137927 18031379
MESH:D007077 Ileal Diseases Indomethacin 4.2318306037 10574470
MESH:D007079 Ileitis Indomethacin 4.5716133968 10651667 10647630
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.5816133044
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.7412013081
MESH:D007248 Infertility, Male Diquat 8.234850670
MESH:D007248 Infertility, Male Ethinyl Estradiol 8.2317937319
MESH:D007248 Infertility, Male Methylnitrosourea 8.237193160
MESH:D007249 Inflammation Dietary Fats 17.0320412841
MESH:D007249 Inflammation Diethylnitrosamine 17.0318785209
MESH:D007249 Inflammation Indomethacin 17.0312568917 3291741 7812673
MESH:D007249 Inflammation Lipopolysaccharides 17.0317237260 17963957 12878042 9205823 17255318
MESH:D007249 Inflammation perfluorooctanoic acid 17.0312083418
MESH:D007249 Inflammation polyphenols 17.0316366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 17.0312200463 12878042
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 3.2018200517
MESH:D007251 Influenza, Human Selenium 3.4116624496
MESH:D007333 Insulin Resistance bisphenol A 13.0916393666
MESH:D007333 Insulin Resistance Dietary Fats 13.0918457598 11836018
MESH:D007333 Insulin Resistance Estradiol 13.0916393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 13.0916306350
MESH:D007410 Intestinal Diseases Indomethacin 12.3715610444 17329856 11686837 15831440 10210152 11855677 18236018 17994277 11713966
MESH:D007410 Intestinal Diseases rebamipide 12.3711686837
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 12.3717994277
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 3.9010783313
MESH:D019586 Intracranial Hypertension Indomethacin 4.5815241188
MESH:D019189 Iron Metabolism Disorders Iron 9.1917163184
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 9.1917255318
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.239022650 8074119
MESH:D007569 Jaw Abnormalities Ethanol 7.7815513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.7816580747
MESH:D007579 Jejunal Diseases Indomethacin 4.2310574470 16133968 18306037
MESH:D007674 Kidney Diseases Acetaminophen 13.7415629191 12587719
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 13.7415369732
MESH:D007674 Kidney Diseases Estradiol 13.7415618244
MESH:D007674 Kidney Diseases Indomethacin 13.7417190690
MESH:D007674 Kidney Diseases ochratoxin A 13.7411409539
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 7.6916518626
MESH:D007676 Kidney Failure, Chronic Selenium 7.6916518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 16.5516705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 16.556582329
MESH:D007680 Kidney Neoplasms Estradiol 16.5515610895
MESH:D007680 Kidney Neoplasms ochratoxin A 16.5516251485
MESH:D007680 Kidney Neoplasms Zidovudine 16.5512579204
MESH:D007859 Learning Disorders Ethanol 3.4615451040
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 6.5811703811 10320625 12228301
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 6.5819248655
MESH:D007938 Leukemia arsenic trioxide 7.9215070760
MESH:D007938 Leukemia Benzene 7.9214694614 18335105 15935818 17119257
MESH:D007938 Leukemia Genistein 7.9217468513 18980019
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 7.5012560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 7.5020370541
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.5316972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 6.5414633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 6.5416572323 10785260 15631656
MESH:D007951 Leukemia, Myeloid arsenic trioxide 7.3719077051
MESH:D007951 Leukemia, Myeloid Benzene 7.3717506065
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 7.0616467208 19850784 16968895 20471514 17050201
MESH:D015470 Leukemia, Myeloid, Acute Benzene 7.0619478238
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 7.0618360721
MESH:D015470 Leukemia, Myeloid, Acute Vitamin D 7.0620368581
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 6.0911468182 12679006 19075265 15622746 17712046 12018890 16112521 11161223 16823087 16330433 17649720 16966277 19642359 16331271 19035177 17217047 12712474 19225113 9834237 15748426 16891316 15336539 17107899 17869043 15213294
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 6.0916766008
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.6116882451
MESH:D007964 Leukocytosis Indomethacin 4.5816537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 4.9217980183
MESH:D007970 Leukopenia Lipopolysaccharides 3.9215821434
MESH:D020961 Lewy Body Disease Iron 4.6716563566
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 4.458812269
MESH:D017880 Limb Deformities, Congenital Ethanol 6.6717676605
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 6.6715526292
MESH:D008064 Lipidoses Amiodarone 2.9217567588 15342952
MESH:D008101 Liver Abscess, Amebic Indomethacin 4.9211479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 15.5417334410 11408273 11903743 16943688 16239168 17157831 21278145 16221502 17174718
MESH:D008103 Liver Cirrhosis Dietary Fats 15.5418296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 15.5418665156 19638242 18522880 18407596 20032147
MESH:D008103 Liver Cirrhosis Ethanol 15.5415289165
MESH:D008103 Liver Cirrhosis Iron 15.5416640825
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.3218295389
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.669327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 16.9712389079 18166357 17761835 12649538 15338365 15876570 15818738 15650968 18006644 17900296 14620537 17525996 10355542 12667390 15925388 16011737 17721639 18481824 17805973 17944888 18395914 18339082 13678700 16097048 15673190 17869086 12898905 12445421 14716496 15931870 15730626 17565644 17823541 14724832 12666154 14716833 16015684 18420326 17557913 15959796 15370692 15362042 14512876 12609069 18210741 16136751 18376398 12586293 18472332 18705752 16248980 18395095 18251166 17481882 18412020 18472094 12546737 15123356 18279442 18187930 18277467 15052691 17708605 20821823 18205269 16116963 17714472 15057751 12632514 12958196 14748882 16033810 18054572 11481614 16638106 17766677 17698563 18263696 17922224 12632512 12445418 17631135 18317297 15996030 16027843 18429990 18418968 15893842 17976157 18156304 16192424 17640975 12741479
MESH:D008106 Liver Cirrhosis, Experimental cis-9, trans-11-conjugated linoleic acid 16.9717869086
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 16.9714716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 16.9718166357
MESH:D008106 Liver Cirrhosis, Experimental Genistein 16.9717823541
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 16.9718194892
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 16.9712878042
MESH:D008106 Liver Cirrhosis, Experimental Melatonin 16.9715925388 16703270 15298665
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 16.9715474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 16.9712878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 16.9715716488 14739098 17355460 17050028 16343077 16511523 15095483 12557150 16248980 15075984 15158331 18606216 15288472 17127702 18458672 15465738 18032466 12175628 15078482 18263696 10677585 18395095 15316131 18615449 17292413 16097051 17629604 15334695 11172339 15362042 18380797 12531686 15474484 12085344 18295389 18416461 18031379 16489207 16126171 15288473 12679928 16098781 11682029 11481614 12891558
MESH:D008107 Liver Diseases Acetaminophen 9.4716611625 12969438 12587719 19014921 16610002 19784758 19460945 11587558
MESH:D008107 Liver Diseases Carbon Tetrachloride 9.4716964402 16246199 15830285 15720792 17285989
MESH:D008107 Liver Diseases Diethylnitrosamine 9.4717034775
MESH:D008107 Liver Diseases polyphenols 9.4716698588
MESH:D008107 Liver Diseases Thioacetamide 9.4718374380 16337175 15158337
MESH:D008108 Liver Diseases, Alcoholic Ethanol 8.9717207112 17347304
MESH:D008108 Liver Diseases, Alcoholic Iron 8.9717207112 16737972
MESH:D017093 Liver Failure Carbon Tetrachloride 9.3215123358
MESH:D017093 Liver Failure Stavudine 9.3218299183
MESH:D017114 Liver Failure, Acute Acetaminophen 12.2917185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 12.2914706259 16899240
MESH:D017114 Liver Failure, Acute Thioacetamide 12.2912479984 15633222 17276928 15313186
MESH:D008113 Liver Neoplasms arsenic trioxide 26.0514682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 26.0521137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 26.0519294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 26.0510737359 18648771 19499222 20101389 21047994 19426721 2422723 19254457 16942905 15885732 19073162 20501860 12112319 15175105 20434301 18644402 19551842 19690152 19256749 19812893 20118626 19294768 12771043 18754104 20492335 18977376 21071580 21278145 19255062 20452335 20405173 19427195 19996281 20137499 19833225 19850985 21167192 18978307 2862719 19642983 20583210 9163691 19090486 19638242
MESH:D008113 Liver Neoplasms Iron 26.0516640825 20302851
MESH:D008113 Liver Neoplasms oxfendazole 26.0518754104
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 26.0514757943 18709148
MESH:D008113 Liver Neoplasms Piperonyl Butoxide 26.0515890375 19690152 18648771 20101389
MESH:D008113 Liver Neoplasms pirinixic acid 26.0515890375 20007298 16377806
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 26.0516984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 20.10598648 6587162 3712494 1399818
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 20.1020377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 20.1012562636
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 20.1015583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 20.1018775883 18253720 19009564 3124819 18544905 18093689 19004024 17174075 16267830 16842330 19539802 17854601 18079962 17942915 2563599 9362446 21159647 18164116 18308698 18282651 19126423 19519916
MESH:D008114 Liver Neoplasms, Experimental systhane 20.1017178689
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 20.1012151625
MESH:D008133 Long QT Syndrome Amiodarone 6.1417391786 15350150 11989578
MESH:D008133 Long QT Syndrome arsenic trioxide 6.1415213294
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 4.7016080182
MESH:D008171 Lung Diseases Amiodarone 5.7112587719
MESH:D008171 Lung Diseases Ozone 5.718266340 19066396
MESH:D017563 Lung Diseases, Interstitial Amiodarone 8.8518516814
MESH:D017563 Lung Diseases, Interstitial Benzene 8.8514698565
MESH:D055370 Lung Injury Lipopolysaccharides 6.7421114838
MESH:D055370 Lung Injury Ozone 6.7420417186
MESH:D008175 Lung Neoplasms arsenic trioxide 19.0011798837 19825857
MESH:D008175 Lung Neoplasms Benzene 19.0012562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 19.0020064080 18816296 18520028 18569708 6695378 20464547 20135361 20869020 17053015
MESH:D008175 Lung Neoplasms bexarotene 19.0017849452
MESH:D008175 Lung Neoplasms Diethylnitrosamine 19.0021163286 20970405 6695378 20512841
MESH:D008175 Lung Neoplasms Indomethacin 19.0011053908 11497255 16537180
MESH:D008175 Lung Neoplasms Iron 19.0016640825
MESH:D008175 Lung Neoplasms Melatonin 19.0017195641
MESH:D008175 Lung Neoplasms Methylnitrosourea 19.0018062963
MESH:D008175 Lung Neoplasms Ozone 19.008597069 7614698
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 19.0019555203 11884234
MESH:D008175 Lung Neoplasms Zidovudine 19.0018800350
MESH:D008180 Lupus Erythematosus, Systemic Melatonin 3.6316373423
MESH:D008223 Lymphoma Benzene 6.0917584886 17119257
MESH:D008223 Lymphoma Methylnitrosourea 6.0916257854 11418001
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 4.0514633661
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.3911161223
MESH:D008268 Macular Degeneration Iron 3.4916640825
MESH:D015674 Mammary Neoplasms, Animal Benzene 3.6812562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 27.9211921183
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 27.9219196722 19196723 15591091
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 27.9212807724
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 27.9211807958 17203775 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental Genistein 27.9214578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental LG 100268 27.9212374698
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 27.9210767621 15313902 10838139 11751437 14633655 11807958 16051031 15113128 17131329 19196723 12931682 15688392 17020996 14999141 16619500 16944150 16827153
MESH:D008325 Mammary Neoplasms, Experimental ochratoxin A 27.9211921183
MESH:D008325 Mammary Neoplasms, Experimental Selenium 27.9215318939
MESH:D020149 Manganese Poisoning Estradiol 3.6919453300
MESH:D008545 Melanoma Vitamin K 3 3.0619082730
MESH:D008546 Melanoma, Experimental Acetaminophen 2.8119513568
MESH:D008569 Memory Disorders Ethanol 3.4618411066 15451040
MESH:D008654 Mesothelioma Selenium 2.4215107826
MESH:D008679 Metaplasia Ozone 4.3110496685
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 5.0517358032
MESH:D008850 Microphthalmos ochratoxin A 5.0520036863
MESH:D008881 Migraine Disorders Indomethacin 6.2711903285
MESH:D008881 Migraine Disorders topiramate 6.2716942474 18765137 18759728 18803445
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 6.5916381670
MESH:D009062 Mouth Neoplasms Indomethacin 6.5912636206
MESH:D009101 Multiple Myeloma arsenic trioxide 9.0219417148 15949261 11468182 14977855 19549372
MESH:D009101 Multiple Myeloma Benzene 9.0217119195
MESH:D009101 Multiple Myeloma S-(dimethylarsino)-glutathione 9.0219417148
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 4.8817086897
MESH:D009135 Muscular Diseases pirinixic acid 2.7516239165
MESH:D009164 Mycobacterium Infections Indinavir 4.6321442799
MESH:D009181 Mycoses Amiodarone 10.5217974566 12754197
MESH:D009181 Mycoses Iron 10.5216640825
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.8818349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 2.6416882451 16105982
MESH:D009203 Myocardial Infarction Genistein 4.3517141266
MESH:D009203 Myocardial Infarction pirinixic acid 4.3519151258
MESH:D017202 Myocardial Ischemia Iron 7.0516604332
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.0512213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 15.2216810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 15.2217141266
MESH:D015428 Myocardial Reperfusion Injury Iron 15.2216604332
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 15.2216411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 8.3718551238
MESH:D009336 Necrosis Melatonin 8.3712195237
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.2216624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 7.263581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 7.263581430 9029167
MESH:D009362 Neoplasm Metastasis Indomethacin 7.2611053908 11239499 16537180
MESH:D009369 Neoplasms Benzo(a)pyrene 5.7111141357
MESH:D009369 Neoplasms Methylnitrosourea 5.7115533788
MESH:D009369 Neoplasms pirinixic acid 5.7117405874
MESH:D009374 Neoplasms, Experimental Indomethacin 7.0810663608 15625704
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 7.0812696579
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 4.0019196722
MESH:D009389 Neovascularization, Pathologic Estradiol 2.9617289903
MESH:D009395 Nephritis, Interstitial Tetracycline 4.009884423
MESH:D009404 Nephrotic Syndrome Iron 3.8517178036
MESH:D009421 Nervous System Malformations bisphenol A 17.4211399458 16427766
MESH:D009421 Nervous System Malformations Estradiol 17.4216427766 11399458
MESH:D009421 Nervous System Malformations Genistein 17.4216427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 17.4214600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 12.876679447
MESH:D009436 Neural Tube Defects arsenic trioxide 12.8710525206
MESH:D009436 Neural Tube Defects Benzene 12.8715643154
MESH:D009436 Neural Tube Defects ochratoxin A 12.8720036863
MESH:D009442 Neurilemmoma Methylnitrosourea 4.7111555667
MESH:D019636 Neurodegenerative Diseases Acetaminophen 14.8018514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 14.8020387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 14.8012349958
MESH:D019636 Neurodegenerative Diseases Iron 14.8017296847 16604332
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.3220387270
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 9.549802331
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 9.549802331
MESH:D009765 Obesity marker/mechanism 19270708
MESH:D009765 Obesity Dietary Fats 3.5311836018 21332399 16723640 17217161 18457598 19632207 20132043 18674790 20518802
MESH:D009765 Obesity pirinixic acid 3.5320558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.386374098
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 11.2112819281 16049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 11.216482804 4026338
MESH:D009784 Occupational Diseases Benzene 11.2116737584 17178637 15913788 17119257 15612468 17479406 15727169 15576619 15935809
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.233988306
MESH:D010003 Osteoarthritis Indomethacin 6.237009135
MESH:D010003 Osteoarthritis Iron 6.2316640825
MESH:D010024 Osteoporosis Genistein 12.6919401787
MESH:D010024 Osteoporosis Iron 12.6916640825 16648989
MESH:D010024 Osteoporosis Isoflavones 12.6916562857
MESH:D010024 Osteoporosis Vitamin D 12.6917882678
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.3716169203
MESH:D010049 Ovarian Diseases bisphenol A 4.2111985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 8.6019769630 12452020 16624393
MESH:D010051 Ovarian Neoplasms Benzene 8.6012562636
MESH:D010051 Ovarian Neoplasms Estradiol 8.6019401270
MESH:D010051 Ovarian Neoplasms Genistein 8.6019005980
MESH:D010146 Pain Acetaminophen 4.6916870215
MESH:D010146 Pain Indomethacin 4.6913679232 3291741 17627676 17440234
MESH:D010149 Pain, Postoperative Indomethacin 3.8912538197 18702446
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 9.4015580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 9.4016540662
MESH:D010190 Pancreatic Neoplasms Ethanol 9.4012384795
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 9.4016965848
MESH:D010195 Pancreatitis Indomethacin 6.4615028970 17883296
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 6.4617698068
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.9611578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 11.307296757
MESH:D010212 Papilloma Hydrogen Peroxide 11.3012065085
MESH:D010212 Papilloma Iron 11.3012065085
MESH:D010235 Paraganglioma arsenic trioxide 3.4419927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 4.9216537180
MESH:D020447 Parasomnias Iron 5.2317352947
MESH:D010300 Parkinson Disease Iron 2.9816563566 16640825
MESH:D020734 Parkinsonian Disorders Indomethacin 7.4612349958
MESH:D020734 Parkinsonian Disorders Melatonin 7.4615574749
MESH:D051302 Paroxysmal Hemicrania Indomethacin 4.9211903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.4612520081
MESH:D010391 Pemphigoid, Bullous Tetracycline 4.6411026799
MESH:D010437 Peptic Ulcer Indomethacin 4.3711148446
MESH:D010518 Periodontitis Indomethacin 4.1217225004
MESH:D010538 Peritonitis Melatonin 8.0615707874
MESH:D010538 Peritonitis Ozone 8.0616369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 3.686228378
MESH:D010900 Pituitary Diseases Iron 4.8816604332
MESH:D010954 Plasmacytoma Selenium 4.1015087411
MESH:D011014 Pneumonia Lipopolysaccharides 8.5311605937 12224865
MESH:D011014 Pneumonia Ozone 8.5318929643 18007984 18381685
MESH:D011041 Poisoning Iron 3.5816604332
MESH:D017119 Porphyria Cutanea Tarda Iron 8.5616640825
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 8.5618163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 2.892563599
MESH:D011225 Pre-Eclampsia Iron 3.8016640825
MESH:D047928 Premature Birth Indomethacin 4.3717000239
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 11.8710548101
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 11.8717132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 11.8711222880 11399792 11118676 11896295
MESH:D017096 Prion Diseases Tetracycline 4.6410903871
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 8.2120887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 8.2120887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.5019131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.5017292933
MESH:D011471 Prostatic Neoplasms bisphenol A 2.5016740699
MESH:D011471 Prostatic Neoplasms equol 2.5016898868 16925846
MESH:D011471 Prostatic Neoplasms Estradiol 2.5016740699
MESH:D011471 Prostatic Neoplasms Genistein 2.5015378649 16925846 15256057
MESH:D011471 Prostatic Neoplasms Isoflavones 2.5017374662 16365062 17219775 17571952
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 2.5012376480 15682402
MESH:D011471 Prostatic Neoplasms methylselenic acid 2.5016205645
MESH:D011507 Proteinuria Indomethacin 3.4511849393
MESH:D011528 Protozoan Infections Iron 5.2316640825
MESH:D011537 Pruritus Ethinyl Estradiol 2.5515861022 16919318
MESH:D011629 Puberty, Precocious bisphenol A 4.0110548101
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.5012490602 11597910 12832656
MESH:D015427 Reperfusion Injury pirinixic acid 1.9519058328
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.1810835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.0918990726
MESH:D012148 Restless Legs Syndrome Iron 3.9316930377
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 7.083692021
MESH:D012162 Retinal Degeneration Methylnitrosourea 7.0818172121 18155124
MESH:D012175 Retinoblastoma Methylnitrosourea 4.7111555667
MESH:D012206 Rhabdomyolysis Lamivudine 4.769296927
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.2216646077
MESH:D012640 Seizures 2,4-dinitrotoluene 6.8318551238
MESH:D012640 Seizures Ethanol 6.839754883
MESH:D012640 Seizures topiramate 6.8316499746
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.3118724381
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 13.2710029692 19755658
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 13.2712065085
MESH:D012878 Skin Neoplasms Iron 13.2712065085
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 13.278532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 13.2716192470
MESH:D012893 Sleep Disorders Melatonin 4.6918182647 16897403 16919138
MESH:D020178 Sleep Disorders, Circadian Rhythm Melatonin 5.8418078449 19452292
MESH:D007319 Sleep Initiation and Maintenance Disorders Melatonin 4.4718078449
MESH:D013088 Spermatocele Ethinyl Estradiol 3.1516709447
MESH:D013272 Stomach Diseases Indomethacin 12.8216280098 10486359 17638125 15472012 10192188 17207306 16184426 17160473 18209964 16113693 18545984 10215738 15038085
MESH:D013272 Stomach Diseases Omeprazole 12.8218545984
MESH:D013272 Stomach Diseases rebamipide 12.8216184426
MESH:D013274 Stomach Neoplasms arsenic trioxide 14.4217007042
MESH:D013274 Stomach Neoplasms Benzene 14.4212562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 14.422093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 14.4218456281
MESH:D013274 Stomach Neoplasms Ethanol 14.4218456281
MESH:D013274 Stomach Neoplasms Indomethacin 14.4215609394
MESH:D013274 Stomach Neoplasms Methylnitrosourea 14.4216257854 18593901 15930296
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 14.4217575124 12958204
MESH:D013274 Stomach Neoplasms rebamipide 14.4215993841
MESH:D013274 Stomach Neoplasms Zidovudine 14.4217696246
MESH:D013276 Stomach Ulcer Amiodarone 15.2718087811
MESH:D013276 Stomach Ulcer Ethanol 15.2716755016 9211565 11906479 9562338 17918041 17189318
MESH:D013276 Stomach Ulcer Indomethacin 15.2714567935 16755016 11729361 12077510 12500499 1323529 17657623 17977527 12467913 10878458 15255614 16631530 11595415 18431645 18181030 17627676 17654042 10423059 11145282 11906479 11523592 15104355 12787963 15138204 18193104 16397915 10750652 16150113 11595431 18209962 18237397 17918041 12498302 17895592 16252198 18299717 17135157 18087811 18543354 16169175 18726076 16934674
MESH:D013276 Stomach Ulcer Melatonin 15.2711523592 12500499 16150113
MESH:D013276 Stomach Ulcer Omeprazole 15.2718237397 17977527 11906479 15991576 10750652 16755016
MESH:D019966 Substance-Related Disorders bisphenol A 3.2216045194 16684133
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.579754883
MESH:D013398 Sudden Infant Death Iron 4.6716640825
MESH:D013610 Tachycardia Amiodarone 3.5511238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 3.4519225199
MESH:D013705 Temporomandibular Joint Disorders polyphenols 4.4617997062
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.4815821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.9011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.4915669648
MESH:D013953 Thymus Neoplasms Benzene 9.6510850423
MESH:D013953 Thymus Neoplasms Methylnitrosourea 9.6511418001
MESH:D013959 Thyroid Diseases Amiodarone 9.4319731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 9.4312697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 20.106582329 7505956 1399818 3712494 6587162
MESH:D013964 Thyroid Neoplasms arsenic trioxide 20.1019014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 20.107505956
MESH:D013964 Thyroid Neoplasms Indomethacin 20.1014736730 18791128 11352223
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 20.107505956 3078959
MESH:D013964 Thyroid Neoplasms Propylthiouracil 20.1015710170
MESH:D013971 Thyrotoxicosis Amiodarone 4.1018020914 19584973
MESH:D013978 Tibial Fractures Estradiol 3.8919048282
MESH:D016171 Torsades de Pointes Amiodarone 7.7011989578 17467628
MESH:D016171 Torsades de Pointes arsenic trioxide 7.7015213294
MESH:D014376 Tuberculosis Iron 3.5516597321
MESH:D014456 Ulcer Indomethacin 4.1210574470 17380554
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 8.7316049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 8.738074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.7312845720 20435036 12973940 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.7317053015
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.5410091137
MESH:D014581 Urticaria Acetaminophen 2.2710982225
MESH:D014591 Uterine Diseases bisphenol A 4.2214652134
MESH:D014594 Uterine Neoplasms Benzene 7.1212562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 7.1214692618
MESH:D014625 Vaginal Neoplasms Zidovudine 4.0012579204
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.8012125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.8314671159 15869587
MESH:D014839 Vomiting Indomethacin 3.9611897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.4615886252
MESH:D015430 Weight Gain Dietary Fats 3.0716723640
Pathway ID Pathway Name
KEGG:01100 Metabolic pathways
REACT:22258 Metabolism of lipids and lipoproteins
KEGG:03320 PPAR signaling pathway
KEGG:00620 Pyruvate metabolism
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB00157 - NADH Dietary supplement;Micronutrient
DB02737 - Oxalate Ion Reducing Agents
DB03461 - 2'-Monophosphoadenosine 5'-Diphosphoribose
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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