AutismKB 2.0

Annotation Detail for ARVCF


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Basic Information Top
Gene Symbol:ARVCF ( FLJ35345 )
Gene Full Name: armadillo repeat gene deleted in velocardiofacial syndrome
Band: 22q11.21
Quick LinksEntrez ID:421; OMIM: 602269; Uniprot ID:ARVC_HUMAN; ENSEMBL ID: ENSG00000099889; HGNC ID: 728
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Desease IDDesease Name
Immune system diseases
Primary immunodeficiency
H00102Classic complement pathway component defects
Desease IDDesease Name
1850Herpes
2006Anorexia nervosa
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of ARVCF mRNAaffects expression 17562736
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ARVCF mRNAaffects cotreatment|increases expression 17942748
D011794 Quercetin Quercetin results in decreased expression of ARVCF mRNAdecreases expression 15309432
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ARVCF mRNAaffects cotreatment|increases expression 17942748
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.4714514962 11752688 15322242
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.6617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8814692618
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 4.0116835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.3411748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.6717084956
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.0211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8915885639
MESH:D001260 Ataxia Telangiectasia Quercetin 5.6115336622
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001327 Autoimmune Diseases Quercetin 4.9719761891
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.4712125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.5115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 3.0015746008
MESH:D001943 Breast Neoplasms Quercetin 2.0918628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.0920435547
MESH:D002105 Cadmium Poisoning Quercetin 6.2716962696
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.1216835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 3.153084413
MESH:D006528 Carcinoma, Hepatocellular Quercetin 3.1512508355 19519916
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 5.5217234771
MESH:D006332 Cardiomegaly Quercetin 7.4519794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 7.4516120746 18850075 18670907
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.5316835633
MESH:D002779 Cholestasis Ethinyl Estradiol 3.1717110522 16919318 11677210 15861022 17333356 16105132 17681005
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.2416354765 15340226 12621046 15668235 8697196
MESH:D003110 Colonic Neoplasms Quercetin 2.4715741050 19056647 16640504 11134977 17148506 17191121 19440933
MESH:D015179 Colorectal Neoplasms Quercetin 2.1918852136 18095365
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.4314669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2720055451 15322242 10048152
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 4.0819496084
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7417107852
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.8614725611 18713872 12540782 17562736 19416960 19370779 18071297 16485898 11461765 12392966 14550746 11529661 17906064 12153990 11743745 16393943 16781746 10663392 12705907 10774834 11739529 11421492 12958197 15968718 19085960 11834606 14986274 19923254 19420014 19739265 15619225 11287661 16081117 16227642 19164858 2444490 12594235 16109766 17522070 10915739 16177239
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.8620420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 3.0511462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.8012711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.6215322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.6912538720
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.429294722 10568697
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.3111564622
MESH:D005234 Fatty Liver Ethinyl Estradiol 3.2415345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 4.0211858732
MESH:D005355 Fibrosis Quercetin 10.7019474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 10.7020067830
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D005909 Glioblastoma Quercetin 3.6319804834
MESH:D005910 Glioma Quercetin 3.1817643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.3210696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.5110048152 11294989
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.7611000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.4516120746 15340226 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.7716354765 18606429 15340226 16959395 8697196
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D006943 Hyperglycemia Quercetin 4.4311834736 18262572
MESH:D006973 Hypertension Quercetin 5.6318356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.6318850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 4.3716569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7317937319
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 2.0312878042 12200463
MESH:D007251 Influenza, Human Quercetin 5.2316624496
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.7616580747
MESH:D007627 Keloid Quercetin 5.5217086741
MESH:D007674 Kidney Diseases Acetaminophen 6.7615629191 12587719
MESH:D007674 Kidney Diseases Quercetin 6.7616962696
MESH:D007938 Leukemia Quercetin 3.3217468513
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 2.5412741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.5412878042
MESH:D008107 Liver Diseases Acetaminophen 1.7019460945 12969438 19784758 16611625 19014921 11587558 12587719 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6317185352 16871587
MESH:D008113 Liver Neoplasms Quercetin 4.9618980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.9616984957
MESH:D008114 Liver Neoplasms, Experimental Quercetin 6.6919519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 6.6912151625
MESH:D008175 Lung Neoplasms Quercetin 2.5016280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.5011884234 19555203
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D009203 Myocardial Infarction Quercetin 3.1219595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.3412213967
MESH:D015428 Myocardial Reperfusion Injury Quercetin 4.1019207477
MESH:D009369 Neoplasms Quercetin 2.9615185748
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.7214600291
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D020078 Neurogenic Inflammation Quercetin 4.8217929310
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.6819495926
MESH:D010051 Ovarian Neoplasms Quercetin 2.8219005980
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D010190 Pancreatic Neoplasms Quercetin 2.9616965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.1511578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.9712520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 4.0718163543
MESH:D011230 Precancerous Conditions Quercetin 4.3519056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.8211118676 11399792 11896295 11222880
MESH:D011471 Prostatic Neoplasms Quercetin 3.5417292933 14715546
MESH:D011537 Pruritus Ethinyl Estradiol 3.9416919318 15861022
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.3518990726
MESH:D012554 Schistosomiasis japonica Quercetin 6.2716862918
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.2016192470
MESH:D013088 Spermatocele Ethinyl Estradiol 4.6616709447
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5215669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.6212697716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 2.9216720314
MESH:D014581 Urticaria Acetaminophen 3.4410982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8014692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.3212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9714671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.9715886252
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA25018
    • No data
    Releated disease ID Related disease Name
    PA445876Tobacco Use Disorder
    PA447216Schizophrenia
    PA443937Drug Toxicity
    PA162263534Ototoxicity
    Releated drug ID Related drug Name
    PA448687bupropion
    PA451257risperidone
    PA449014cisplatin
    Drug Bank Top

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      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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