AutismKB 2.0

Annotation Detail for MEST


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MEST ( DKFZp686L18234,MGC111102,MGC8703,PEG1 )
Gene Full Name: mesoderm specific transcript homolog (mouse)
Band: 7q32.2
Quick LinksEntrez ID:4232; OMIM: 601029; Uniprot ID:MEST_HUMAN; ENSEMBL ID: ENSG00000106484; HGNC ID: 7028
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1788Infiltrating cancer
1944Breast cancer
2124Autistic disorder
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of MEST mRNAaffects expression 17562736
C015001 arsenite arsenite results in decreased expression of MEST mRNAdecreases expression 18929588
C015001 arsenite TRP53 protein affects the reaction [arsenite results in decreased expression of MEST mRNA]affects reaction|decreases expression 18929588
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MEST mRNAaffects cotreatment|increases expression 18164116
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of MEST mRNAincreases expression 20382639
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of MEST mRNAdecreases expression 15336504
D016572 Cyclosporine Cyclosporine results in decreased expression of MEST mRNAdecreases expression 20106945
D002945 Cisplatin MEST protein affects the susceptibility to Cisplatinaffects response to substance 16217747
D004041 Dietary Fats Dietary Fats results in increased expression of MEST mRNAincreases expression 18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MEST mRNAaffects cotreatment|increases expression 18164116
D004317 Doxorubicin MEST protein affects the susceptibility to Doxorubicinaffects response to substance 16217747
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MEST mRNAaffects cotreatment|increases expression 17942748
D008942 Mitoxantrone MEST protein affects the susceptibility to Mitoxantroneaffects response to substance 16217747
C041786 palm oil palm oil results in increased expression of MEST mRNAincreases expression 18042831
D011374 Progesterone Progesterone results in increased expression of MESTincreases expression 17510236
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of MEST mRNAincreases expression 12377990
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MEST mRNAaffects cotreatment|increases expression 17942748
D019772 Topotecan MEST protein affects the susceptibility to Topotecanaffects response to substance 16217747
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.8714514962 15322242 11752688
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9717505938
MESH:D058186 Acute Kidney Injury Cisplatin 3.9615814532 12690470 17670903
MESH:D000230 Adenocarcinoma Cisplatin 7.1811798837 17638652
MESH:D000230 Adenocarcinoma Doxorubicin 7.1817418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 7.1814692618
MESH:D000236 Adenoma beta-Naphthoflavone 6.8919389873
MESH:D000236 Adenoma Diethylnitrosamine 6.8910737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 10.1216434500 19052882 18056438 17620307 17162532 19061943
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.1216835633
MESH:D000419 Albuminuria Doxorubicin 4.5521441931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9511748828
MESH:D000799 Angioedema Acetaminophen 3.8710982225
MESH:D001161 Arteriosclerosis Dietary Fats 9.9515238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.9511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6615885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.0512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7615746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 12.1614601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 12.1614601052
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.3717868700
MESH:D001930 Brain Injuries Progesterone 4.2715665606 15380490 15845082
MESH:D001932 Brain Neoplasms Doxorubicin 3.8117150277
MESH:D001943 Breast Neoplasms Cisplatin 2.9619526202 18382427
MESH:D001943 Breast Neoplasms Dietary Fats 2.9620435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.9617474063
MESH:D001943 Breast Neoplasms Doxorubicin 2.9615136595 19526202 18382427 15567936 16264153 17983394 15939500 11325840 18628466 15668708 18695136 16115903 16096432 15994142 16935488 16322301 15993339 17426702 15634643 18234424 17369602 16826403 16595493 15692762
MESH:D001943 Breast Neoplasms Progesterone 2.9616175315 15562024 17614352
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.9620435547
MESH:D002276 Carcinoid Tumor Doxorubicin 4.8416051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8016835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 6.613084413
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 6.6117982673
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 6.6116779866 20432363 20214788 20935162 20007298 10672840 18506893 20101231 21159647 16830150 16935385 18665156 19701751 16540662 19539802 10737359 17138121 17428255 19919837 16698587 16288022 18971187 17761372 19383236 19208518 18691550 20727157 18056438 19171122 20084675 18393292 20512989 19052882 19107877 18788625 19519916 18210153 16681979 16878318 11831363 16328049 18978308 17978847 17162532 17173139 16807293 16569478 20514400 16502159 18785209 3084413 19394651 17055752 18494052 19822196 20524982 3581430 19418558 19335982
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 6.6116023760 16234567 17876044 18059187
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 3.0412023789 16685392
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 3.1616201981 1485588
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 4.986189445 18337622 17066447
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 4.986189445
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3718850075 18670907 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.5316278810 17519947 17007740 16731534 17131338 17351982 16364871 16269455 17382496 17329180 16455267 15476868 15792986 15505089 15811867 17308081 16612575 18627295 16952015 16109756 17974986 16651473 16242529 17924179 17928571
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.9416243910 17334414
MESH:D002386 Cataract Acetaminophen 2.5810977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.1620889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 11.1612371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 11.1617174075 2727394 21159647 7505956
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.3319052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.3316835633
MESH:D002779 Cholestasis Cyclosporine 7.7819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.7816105132 15861022 17681005 11677210 16919318 17110522 17333356
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1015340226 15668235 8697196 12621046 16354765
MESH:D003110 Colonic Neoplasms arsenite 2.5915037631
MESH:D015179 Colorectal Neoplasms Cisplatin 2.7715273666
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.7718259882 18802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0614669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2510048152 20055451 15322242
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.2220387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2217107852
MESH:D003929 Diabetic Neuropathies Progesterone 4.5117187935
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 8.9811743745 19370779 12705907 12958197 16177239 16393943 16781746 19923254 17906064 10663392 11739529 14550746 15968718 19164858 19085960 16485898 17522070 11529661 14725611 15619225 11421492 12540782 19416960 12392966 18071297 17562736 10915739 16227642 19739265 12153990 11287661 11834606 11461765 2444490 18713872 14986274 16109766 10774834 16081117 12594235 19420014
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 8.9819107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 8.9817416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 8.9820420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1319426721
MESH:D004362 Drug Toxicity Cisplatin 13.7912231392 15033597 19839026 12649298
MESH:D004362 Drug Toxicity Doxorubicin 13.7918602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 13.7911462148
MESH:D050171 Dyslipidemias Dietary Fats 3.4518367378
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.3811000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9316714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.0712538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 9.0717692515
MESH:D016889 Endometrial Neoplasms Doxorubicin 3.4517359293
MESH:D004715 Endometriosis Progesterone 8.9416134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.9410568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.1918037988
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.1516302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.6320426865
MESH:D004938 Esophageal Neoplasms Cisplatin 4.6317638652 16785472 15464296 16481741 15173087
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0111564622
MESH:D005234 Fatty Liver arsenite 24.7318296743
MESH:D005234 Fatty Liver Cyclosporine 24.7319224547
MESH:D005234 Fatty Liver Dietary Fats 24.7317967931 19551842 18296743 19004024
MESH:D005234 Fatty Liver Diethylnitrosamine 24.7321071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 24.7315345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4711858732
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.6119069698
MESH:D005355 Fibrosis arsenite 21.3018296743
MESH:D005355 Fibrosis Cyclosporine 21.3012639820 12168785
MESH:D005355 Fibrosis Dietary Fats 21.3018296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 21.3020067830
MESH:D005756 Gastritis Acetaminophen 3.7116983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.248708960
MESH:D005909 Glioblastoma Doxorubicin 3.3517150277
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6210696789
MESH:D006258 Head and Neck Neoplasms Cisplatin 8.0515102660 15464296
MESH:D006258 Head and Neck Neoplasms Doxorubicin 8.0515692506
MESH:D034381 Hearing Loss Cisplatin 4.3019898482
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.4215464296
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3310048152 11294989
MESH:D006331 Heart Diseases Doxorubicin 8.0718674790 17875725 14766674 18006777 17888722 16244372 16330681 16495754 12587719 16879835 16707910 16144979 16244371
MESH:D006331 Heart Diseases Mitoxantrone 8.0716019553
MESH:D006333 Heart Failure Doxorubicin 3.3417481944
MESH:D006394 Hemangiosarcoma Doxorubicin 3.9015692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.4415720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3411000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.9115340226 16120746 12621046
MESH:D006689 Hodgkin Disease Cisplatin 7.6516200630 16170182
MESH:D006689 Hodgkin Disease Doxorubicin 7.6518501091 17606976 15147373
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0818606429 15340226 16354765 8697196 16959395
MESH:D006930 Hyperalgesia Acetaminophen 2.7016870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.6021332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.6221332399
MESH:D006973 Hypertension Cyclosporine 4.9510903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.9518670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8216945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.4115869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4917937319
MESH:D007249 Inflammation Dietary Fats 11.9720412841
MESH:D007249 Inflammation Diethylnitrosamine 11.9718785209
MESH:D007249 Inflammation Progesterone 11.9715869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.9712200463 12878042
MESH:D007333 Insulin Resistance Dietary Fats 3.1111836018 18457598
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3416580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.4715604871
MESH:D007673 Kidney Cortex Necrosis Cisplatin 5.1715464296
MESH:D007674 Kidney Diseases Acetaminophen 14.4812587719 15629191
MESH:D007674 Kidney Diseases Cisplatin 14.4812649298 15190930 19839026 12231392 18289764
MESH:D007674 Kidney Diseases Cyclosporine 14.4818776723 10903974 8314463
MESH:D007674 Kidney Diseases Doxorubicin 14.4815369732 16775033 15699352
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.1616707910
MESH:D007680 Kidney Neoplasms Cyclosporine 2.7412371664
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.8211231351
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.1916085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Mitoxantrone 3.7918172266
MESH:D008103 Liver Cirrhosis arsenite 11.1118296743
MESH:D008103 Liver Cirrhosis Dietary Fats 11.1118296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 11.1119638242 18665156 18407596 18522880 20032147
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 2.4316439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.4312878042
MESH:D008107 Liver Diseases Acetaminophen 3.9119460945 16611625 16610002 12587719 19784758 11587558 19014921 12969438
MESH:D008107 Liver Diseases Diethylnitrosamine 3.9117034775
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2416871587 17185352
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 7.4619389873 21295105
MESH:D008113 Liver Neoplasms Diethylnitrosamine 7.4619812893 20501860 18754104 20118626 19254457 19642983 15175105 19255062 18644402 20583210 19426721 19090486 20101389 19996281 19690152 19833225 12771043 2422723 16942905 18978307 18977376 9163691 19073162 20434301 20137499 20492335 19427195 10737359 18648771 19551842 21278145 20405173 12112319 2862719 19499222 15885732 20452335 19850985 19638242 19256749 19294768 21071580 21047994 21167192
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 7.4616984957
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 14.1718164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 14.1718308698 16267830 19004024 19126423 18093689 18079962 18164116 19009564 19519916 18775883 18253720 19539802 17942915 18544905 21159647 3124819 17174075 2563599 18282651 9362446 16842330 17854601
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 14.1717085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 14.1712151625
MESH:D008175 Lung Neoplasms arsenite 6.6116809336
MESH:D008175 Lung Neoplasms Cisplatin 6.6117225452 11798837 6189445
MESH:D008175 Lung Neoplasms Diethylnitrosamine 6.6120512841 20970405 21163286 6695378
MESH:D008175 Lung Neoplasms Doxorubicin 6.6117418594 6189445
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.6111884234 19555203
MESH:D008223 Lymphoma Doxorubicin 3.4616098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.7917654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.5815621674
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 6.2415458769
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 6.2411408345 17203775
MESH:D008545 Melanoma Cisplatin 3.6316432458 16248763 17023156 18176117 18505091 12374674 15577323 12883367 16809738 11135225 17761969 18332650 12393984
MESH:D008545 Melanoma Doxorubicin 3.6316827129
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.7915990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5819513568
MESH:D008654 Mesothelioma Cisplatin 6.4617638057
MESH:D008654 Mesothelioma Doxorubicin 6.4617638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.8216801185
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.5015792986
MESH:D052016 Mucositis Doxorubicin 4.8117415656
MESH:D009203 Myocardial Infarction Doxorubicin 2.9519429709 15857846
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0212213967
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.883581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 5.8818259882
MESH:D009369 Neoplasms Cisplatin 5.6516773208
MESH:D009369 Neoplasms Mitoxantrone 5.6516640825
MESH:D009389 Neovascularization, Pathologic arsenite 4.4315738583
MESH:D009395 Nephritis, Interstitial Cisplatin 4.5215464296
MESH:D009401 Nephrosis Doxorubicin 4.7816899518 16636307
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.4717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 9.3119348381 18481113
MESH:D009404 Nephrotic Syndrome Doxorubicin 9.3116889571 15640375
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.2214600291
MESH:D009447 Neuroblastoma Cisplatin 11.598761367
MESH:D009447 Neuroblastoma Doxorubicin 11.5915555623
MESH:D009447 Neuroblastoma Topotecan 11.5915176712
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.1918514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.1920387270
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.728761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.1520387270
MESH:D009765 Obesity Dietary Fats 2.2920132043 17217161 18674790 21332399 11836018 16723640 19632207 20518802 18457598
MESH:D012516 Osteosarcoma Doxorubicin 4.1115930896
MESH:D010051 Ovarian Neoplasms Cisplatin 5.1117225452 19769630 15464296 6897625
MESH:D010051 Ovarian Neoplasms Progesterone 5.1117393432 16525653
MESH:D010146 Pain Acetaminophen 2.3916870215
MESH:D010190 Pancreatic Neoplasms Cisplatin 5.4519003803
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.4516540662
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6911578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2812520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 4.3215464296
MESH:D003557 Phyllodes Tumor Doxorubicin 5.1917983394
MESH:D010997 Pleural Neoplasms Cisplatin 14.0417638057
MESH:D010997 Pleural Neoplasms Doxorubicin 14.0417638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5718163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.9512371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.952563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2111118676 11399792 11222880 11896295
MESH:D011471 Prostatic Neoplasms Doxorubicin 3.5615749863 16729912 16868541 15897917 16888761 18437689
MESH:D011537 Pruritus Ethinyl Estradiol 3.3316919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.2316882103
MESH:D051437 Renal Insufficiency Cisplatin 10.4215464296
MESH:D051437 Renal Insufficiency Doxorubicin 10.4217922066
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8518990726
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.8618045962
MESH:D012509 Sarcoma Doxorubicin 3.9916767912 15675481 15625365 17203757 18313854 17710206
MESH:D012512 Sarcoma, Ewing's Cisplatin 10.4814601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 10.4814601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.8117846226
MESH:D012878 Skin Neoplasms Doxorubicin 9.4815692506
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 9.488532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.4816192470
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 5.3715464296
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.5815625365 16767912 17203757
MESH:D013088 Spermatocele Ethinyl Estradiol 3.9716709447
MESH:D013119 Spinal Cord Injuries Progesterone 4.3016503802 15862959
MESH:D013274 Stomach Neoplasms Cisplatin 2.6115958060 18396642 17522103
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.6118456281
MESH:D013736 Testicular Neoplasms Cisplatin 4.6417225452 15464296
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6311994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1515669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9312697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 7.307505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 7.3016010429 17909728
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 5.4315464296 12973940 17225452
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 5.4317653716
MESH:D014581 Urticaria Acetaminophen 2.9810982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 4.2116803524
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3114692618
MESH:D014605 Uveitis Cyclosporine 4.011336536
MESH:D014625 Vaginal Neoplasms Cisplatin 4.6215577323
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5414671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.2317678736 16364871 17334414 17638931
MESH:D014839 Vomiting Cisplatin 4.7511897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2815886252
MESH:D015430 Weight Gain Dietary Fats 3.7416723640
MESH:D014985 Xerophthalmia Cyclosporine 4.4717120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved