Annotation Detail for MET
Basic Information Top
Gene Symbol: | MET ( AUTS9,HGFR,RCCP2,c-Met ) |
---|---|
Gene Full Name: | met proto-oncogene (hepatocyte growth factor receptor) |
Band: | 7q31 |
Quick Links | Entrez ID:4233; OMIM: 164860; Uniprot ID:MET_HUMAN; ENSEMBL ID: ENSG00000105976; HGNC ID: 7029 |
Relate to Another Database: | SFARIGene; denovo-db |
Pathway ID | Pathway Name |
---|---|
hsa04360 | Axon guidance |
hsa04144 | Endocytosis |
hsa05144 | Malaria |
hsa05120 | Epithelial cell signaling in Helicobacter pylori infection |
hsa05211 | Renal cell carcinoma |
hsa05100 | Bacterial invasion of epithelial cells |
hsa04520 | Adherens junction |
hsa05218 | Melanoma |
hsa04510 | Focal adhesion |
hsa04060 | Cytokine-cytokine receptor interaction |
hsa05200 | Pathways in cancer |
Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
---|---|---|---|---|
C548651 | 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester | 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of MET mRNA | decreases expression | 19933214 |
C478479 | ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide) | ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide) affects the activity of MET protein mutant form | affects activity | 18632630 |
C478479 | ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide) | ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide) inhibits the reaction [HGF protein results in increased phosphorylation of MET protein] | decreases reaction|increases phosphorylation | 18632630 |
C478479 | ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide) | ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide) results in decreased phosphorylation of and results in decreased activity of MET protein | decreases activity|decreases phosphorylation | 18632630 |
C478479 | ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide) | 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide inhibits the reaction [MET protein mutant form results in decreased susceptibility to ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide)] | decreases reaction|decreases response to substance | 18632630 |
C478479 | ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide) | MET protein mutant form results in decreased susceptibility to ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide) | decreases response to substance | 18632630 |
C016601 | 4-hydroxytamoxifen | 4-hydroxytamoxifen results in decreased expression of MET mRNA | decreases expression | 17640349 |
C498826 | 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide | 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide inhibits the reaction [MET protein mutant form results in decreased susceptibility to ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide)] | decreases reaction|decreases response to substance | 18632630 |
D000082 | Acetaminophen | Acetaminophen affects the expression of MET mRNA | affects expression | 17562736 |
C430898 | AGN 194204 | AGN 194204 results in decreased expression of MET protein | decreases expression | 15318936 |
C103303 | alitretinoin | alitretinoin results in increased phosphorylation of MET protein | increases phosphorylation | 16192631 |
D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of MET mRNA | affects expression | 16483693 |
C006632 | arsenic trioxide | arsenic trioxide results in decreased expression of MET mRNA | decreases expression | 19769630 20458559 |
D017638 | Asbestos, Crocidolite | Asbestos, Crocidolite results in increased expression of MET mRNA | increases expression | 12839939 |
D017638 | Asbestos, Crocidolite | FOSL1 protein promotes the reaction [Asbestos, Crocidolite results in increased expression of MET mRNA] | increases expression|increases reaction | 12839939 |
D017638 | Asbestos, Crocidolite | Asbestos, Crocidolite results in increased expression of MET mRNA | increases expression | 12839939 |
D017638 | Asbestos, Crocidolite | FOSL1 protein promotes the reaction [Asbestos, Crocidolite results in increased expression of MET mRNA] | increases expression|increases reaction | 12839939 |
D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of MET mRNA | decreases expression | 20889680 |
D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of MET mRNA | decreases expression | 20889680 |
D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of MET protein | decreases expression | 20889680 |
D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MET mRNA | decreases expression | 19150397 |
C053541 | bicalutamide | bicalutamide inhibits the reaction [Testosterone results in increased expression of MET mRNA] | decreases reaction|increases expression | 17371283 11139396 |
C002791 | bismuth tripotassium dicitrate | bismuth tripotassium dicitrate results in increased expression of MET mRNA | increases expression | 15912405 |
C006780 | bisphenol A | bisphenol A results in increased expression of MET mRNA | increases expression | 19371625 |
D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide results in decreased expression of MET mRNA | decreases expression | 15336504 |
D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased phosphorylation of and results in decreased activity of MET protein | decreases activity|decreases phosphorylation | 17976157 |
D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of MET mRNA | increases expression | 17484886 |
D002251 | Carbon Tetrachloride | MET protein affects the reaction [Carbon Tetrachloride results in increased expression of SPP1 protein] | affects reaction|increases expression | 15070743 |
D002251 | Carbon Tetrachloride | [Carbon Tetrachloride co-treated with TM4SF4 protein] results in decreased expression of MET mRNA | affects cotreatment|decreases expression | 17069928 |
D002251 | Carbon Tetrachloride | [Carbon Tetrachloride co-treated with TM4SF4 protein] results in decreased expression of MET protein | affects cotreatment|decreases expression | 17069928 |
D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased expression of MET mRNA | decreases expression | 12832660 |
D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of MET mRNA | increases expression | 17009398 |
C031662 | CB 3717 | CB 3717 inhibits the reaction [Testosterone results in increased expression of MET mRNA] | decreases reaction|increases expression | 11139396 |
C031662 | CB 3717 | CB 3717 results in increased expression of MET mRNA | increases expression | 11139396 17371283 |
C031662 | CB 3717 | Testosterone inhibits the reaction [CB 3717 results in increased expression of MET mRNA] | decreases reaction|increases expression | 11139396 |
D002509 | Cephaloridine | Cephaloridine results in increased expression of MET mRNA | increases expression | 18172885 |
D003042 | Cocaine | Cocaine affects the expression of MET mRNA | affects expression | 15681117 |
C014347 | decitabine | decitabine results in decreased expression of MET mRNA | decreases expression | 19363521 |
C014347 | decitabine | TP53 protein affects the reaction [decitabine results in decreased expression of MET mRNA] | affects reaction|decreases expression | 19363521 |
D004052 | Diethylnitrosamine | CTNNB1 protein promotes the reaction [Diethylnitrosamine results in decreased expression of MET protein] | decreases expression|increases reaction | 20583210 |
D004052 | Diethylnitrosamine | Diethylnitrosamine results in decreased expression of MET protein | decreases expression | 20583210 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of ATP13A4 mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of ATP2A1 mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of CTSC mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of DBP mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of GADD45B mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of GKN3 mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of H2-D1 mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of IFITM5 mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of ITPKB mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of KRT13 mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of LANCL1 mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of MS4A1 mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of OLFR771 mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of PLA2G2C mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of SLC22A4 mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of TSGA10 mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of ZFP3 mRNA] | decreases expression|decreases reaction | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ABCA3 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ABTB2 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ACO2 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of AFM mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of AGXT mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of AHSA1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of AP2B1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARG1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARHGAP19 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARHGAP5 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARHGEF19 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARL5A mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARRB1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ASB14 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ASNS mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ATP11C mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ATP8B4 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of B2M mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of B3GAT1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of BCKDHB mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of BST2 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of C1QC mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CAPZA2 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDK2AP2 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CIB3 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CLOCK mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CML5 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of COL6A1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CPEB2 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CTSS mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYB5 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYP2D13 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYP2D22 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYP3A13 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYP3A44 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYP4F16 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of DCT mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of DGUOK mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of DUSP1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of DYNLT1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of EPOR mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of EVI2B mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of EXOC8 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of FAM20B mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of G6PC mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of GADD45G mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of GBP9 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of GFER mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of GIMAP7 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of GLO1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of GSTM2 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of H19 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of H2-BL mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of HIRA mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of HNRPC mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of HSD17B11 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of HSPA1B mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of HSPD1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of HTR2A mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ID3 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of IGF1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of IGFBP1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of KCNAB1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of KCNJ14 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of KLF10 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of KLF12 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of LRP1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of LRRC68 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of MALAT1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of MEGF9 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of MKI67 protein] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of MUG1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of MUG2 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NAT8 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NDRG1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NDUFA12 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NDUFA7 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NKX6-2 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NLRP3 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NPR2 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NRN1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of OAT mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of OLFM1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of OLFR203 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of OLFR677 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of P2RX4 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of P2RX7 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PALMD mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PARD6A mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PEBP1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PIGR mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PLA1A mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PLA2G16 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PLA2G2C mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PNRC1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PPM1K mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RAB6B mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RABGAP1L mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RBBP4 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RBP1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RHOH mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RPL17 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RPL27A mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RPL32 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RPL35 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RPL41 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RPL9 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SBP mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SCD2 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SCGB1C1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SCN8A mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SCTR mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SERF2 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SH2D6 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SLC16A10 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SLC19A2 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SLC25A48 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SLC47A1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SMOX mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SOD1 protein] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ST7 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SYT5 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of TCEB2 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of TLN1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of TMEM98 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of TMPRSS3 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of TMSB4X mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of TRAPPC5 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of TRPM1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of UBC mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of UGT2B1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of UTRN mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of VEPH1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of VIM mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of VSIG10 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of VSIG4 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of WWOX mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ZCCHC18 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ZFP300 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ZFP36L1 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ZZZ3 mRNA] | decreases reaction|increases expression | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of EGFR protein] | decreases reaction|increases activity|increases phosphorylation | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of MAPK1 protein] | decreases reaction|increases activity|increases phosphorylation | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of MAPK3 protein] | decreases reaction|increases activity|increases phosphorylation | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of PRKCA protein] | decreases reaction|increases activity|increases phosphorylation | 17942915 |
D004052 | Diethylnitrosamine | MET protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of PRKCB protein] | decreases reaction|increases activity|increases phosphorylation | 17942915 |
D004052 | Diethylnitrosamine | MET protein results in increased susceptibility to Diethylnitrosamine | increases response to substance | 17942915 |
D004054 | Diethylstilbestrol | Diethylstilbestrol results in increased expression of MET mRNA | increases expression | 19371625 |
D004128 | Dimethylnitrosamine | Dimethylnitrosamine affects the expression of MET mRNA | affects expression | 16596271 |
D004317 | Doxorubicin | Doxorubicin results in decreased expression of MET protein | decreases expression | 16109756 18083897 |
D004317 | Doxorubicin | HGF protein inhibits the reaction [Doxorubicin results in decreased expression of MET protein] | decreases expression|decreases reaction | 16109756 18083897 |
C045651 | epigallocatechin gallate | epigallocatechin gallate inhibits the reaction [HGF protein results in increased phosphorylation of MET protein] | decreases reaction|increases phosphorylation | 19244381 |
C010452 | estradiol-17 beta-benzoate | estradiol-17 beta-benzoate affects the expression of MET mRNA | affects expression | 15059950 |
D004958 | Estradiol | Estradiol results in increased expression of MET mRNA | increases expression | 17640349 |
C015854 | estradiol valerate | estradiol valerate results in decreased expression of MET mRNA | decreases expression | 15972882 |
D000431 | Ethanol | Ethanol results in increased expression of MET mRNA | increases expression | 15353170 16946407 |
D015025 | Zearalenone | Zearalenone results in increased expression of MET mRNA | increases expression | 19371625 |
D005492 | Folic Acid | Folic Acid inhibits the reaction [Testosterone results in increased expression of MET mRNA] | decreases reaction|increases expression | 11139396 |
D005492 | Folic Acid | Folic Acid results in increased expression of MET mRNA | increases expression | 11139396 |
D005492 | Folic Acid | Testosterone inhibits the reaction [Folic Acid results in increased expression of MET mRNA] | decreases reaction|increases expression | 11139396 |
D019833 | Genistein | Genistein results in increased expression of MET mRNA | increases expression | 19371625 |
C006552 | kaempferol | kaempferol inhibits the reaction [HGF protein results in increased phosphorylation of MET protein] | decreases reaction|increases phosphorylation | 19244381 |
D007854 | Lead | Lead results in decreased expression of MET protein | decreases expression | 17298174 |
C008261 | lead acetate | lead acetate results in decreased expression of MET protein | decreases expression | 17298174 |
D008767 | Methylmercury Compounds | Methylmercury Compounds results in decreased expression of MET protein | decreases expression | 17298174 |
D008769 | Methylnitronitrosoguanidine | Methylnitronitrosoguanidine results in increased expression of MET mRNA | increases expression | 12634122 |
C040015 | myricetin | myricetin inhibits the reaction [HGF protein results in increased phosphorylation of MET protein] | decreases reaction|increases phosphorylation | 19244381 |
C484027 | oligofectamine | oligofectamine results in increased expression of MET mRNA | increases expression | 14668052 |
C016340 | o,p'-DDT | o,p'-DDT results in increased expression of MET mRNA | increases expression | 19371625 |
D010269 | Paraquat | Paraquat results in decreased expression of MET protein | decreases expression | 17298174 |
D010634 | Phenobarbital | Phenobarbital results in increased expression of MET mRNA | increases expression | 19270015 19363144 |
C006253 | pirinixic acid | pirinixic acid results in increased expression of MET mRNA | increases expression | 18301758 |
D010972 | Platelet Activating Factor | Platelet Activating Factor results in decreased expression of MET mRNA | decreases expression | 15307983 |
C443641 | poly(propyleneimine) | poly(propyleneimine) analog affects the expression of MET mRNA | affects expression | 16308212 |
D011794 | Quercetin | Quercetin inhibits the reaction [HGF protein results in increased phosphorylation of MET protein] | decreases reaction|increases phosphorylation | 19244381 |
C037219 | quinoline | quinoline analog results in decreased activity of MET protein | decreases activity | 17964000 |
C059514 | resveratrol | resveratrol results in increased expression of MET mRNA | increases expression | 19371625 |
C009166 | retinol acetate | retinol acetate results in increased expression of MET mRNA | increases expression | 16772331 |
C009277 | sodium arsenate | sodium arsenate results in decreased expression of MET mRNA | decreases expression | 16882884 |
C017947 | sodium arsenite | sodium arsenite affects the expression of MET mRNA | affects expression | 16507464 |
C017947 | sodium arsenite | sodium arsenite results in increased expression of MET mRNA | increases expression | 16876216 11241755 |
C025462 | sulindac sulfide | sulindac sulfide inhibits the reaction [CTNNB1 protein results in increased expression of MET protein] | decreases reaction|increases expression | 14710233 |
D013739 | Testosterone | bicalutamide inhibits the reaction [Testosterone results in increased expression of MET mRNA] | decreases reaction|increases expression | 11139396 17371283 |
D013739 | Testosterone | CB 3717 inhibits the reaction [Testosterone results in increased expression of MET mRNA] | decreases reaction|increases expression | 11139396 |
D013739 | Testosterone | Folic Acid inhibits the reaction [Testosterone results in increased expression of MET mRNA] | decreases reaction|increases expression | 11139396 |
D013739 | Testosterone | Testosterone inhibits the reaction [CB 3717 results in increased expression of MET mRNA] | decreases reaction|increases expression | 11139396 |
D013739 | Testosterone | Testosterone inhibits the reaction [Folic Acid results in increased expression of MET mRNA] | decreases reaction|increases expression | 11139396 |
D013739 | Testosterone | Testosterone results in increased expression of MET mRNA | increases expression | 11139396 17371283 |
D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of MET mRNA | increases expression | 20067830 |
D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of MET mRNA | decreases expression | 19933214 |
D014212 | Tretinoin | Tretinoin results in increased expression of MET mRNA | increases expression | 16051641 |
C025643 | vinclozolin | vinclozolin affects the expression of MET mRNA | affects expression | 19015723 |
C025643 | vinclozolin | vinclozolin results in decreased expression of MET mRNA | decreases expression | 18220299 |
Drugbank ID | Action | Drug Name | Description |
---|---|---|---|
DB02152 | - | K-252a | Enzyme Inhibitors |
DB06896 | - | 1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide | |
DB06995 | - | N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide | |
DB06997 | - | 2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide | |
DB07369 | - | N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide | |
DB07969 | - | 3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol | |
DB08584 | - | 6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline | |
DB08700 | - | 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine | |
DB08791 | - | 1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE |