AutismKB 2.0

Annotation Detail for MFI2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MFI2 ( CD228,FLJ38863,MAP97,MGC4856,MTF1 )
Gene Full Name: antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
Band: 3q28-q29
Quick LinksEntrez ID:4241; OMIM: 155750; Uniprot ID:TRFM_HUMAN; ENSEMBL ID: ENSG00000163975; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1740Alzheimer's disease
1770Melanoma
1886Angiomyolipoma
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D003474 Curcumin Curcumin results in decreased expression of MFI2 mRNAdecreases expression 17198877
D002117 Calcitriol Calcitriol results in increased expression of MFI2 mRNAincreases expression 16002434
C084656 paricalcitol [Phosphorus co-treated with paricalcitol] results in increased expression of MFI2 mRNAaffects cotreatment|increases expression 17715259
D010758 Phosphorus [Phosphorus co-treated with paricalcitol] results in increased expression of MFI2 mRNAaffects cotreatment|increases expression 17715259
D014635 Valproic Acid Valproic Acid results in increased expression of MFI2 mRNAincreases expression 19101580
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 4.028875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.3019490988
MESH:D019973 Alcohol-Related Disorders Curcumin 5.6917887948
MESH:D000544 Alzheimer Disease Curcumin 2.6715590663
MESH:D000550 Amblyopia Valproic Acid 5.8517688650
MESH:D001008 Anxiety Disorders Valproic Acid 3.8617497229
MESH:D001172 Arthritis, Rheumatoid Curcumin 2.8016807698
MESH:D050197 Atherosclerosis Curcumin 3.5118704882
MESH:D001321 Autistic Disorder Valproic Acid 1.9817688650 19232924 15238991 18396377 17507914 17157402 18316065 18940202 18558336 16609825 18985861 18775368 20603192 18177632 19460635
MESH:D001327 Autoimmune Diseases Curcumin 4.9819761891
MESH:D001714 Bipolar Disorder Valproic Acid 3.2317594078 20046352
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.618888407
MESH:D002545 Brain Ischemia Curcumin 4.8716770732
MESH:D001932 Brain Neoplasms Curcumin 4.2817596214
MESH:D001943 Breast Neoplasms Calcitriol 2.4511237771
MESH:D001943 Breast Neoplasms Curcumin 2.4518462866 18593918 16243823 19250217
MESH:D002277 Carcinoma Curcumin 4.1218593918
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 3.0718414057
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 5.2311237771
MESH:D002294 Carcinoma, Squamous Cell Curcumin 5.2318462866
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8120734317
MESH:D003092 Colitis Curcumin 4.6616782535 16804969 18200517
MESH:D003103 Coloboma Curcumin 4.9218809619
MESH:D003110 Colonic Neoplasms Curcumin 2.5519359593 16340194
MESH:D016510 Corneal Neovascularization Curcumin 5.3818497527
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.9017688650 8888407 16575769
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 2.7718403477
MESH:D003928 Diabetic Nephropathies Curcumin 4.3318204486
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 2.2519641884 1733752
MESH:D004381 Duodenal Ulcer Curcumin 4.4917351913
MESH:D004421 Dystonia Valproic Acid 4.451851702
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 4.3715138306
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.643659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 4.533922381 16628512
MESH:D004827 Epilepsy Valproic Acid 3.0920417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.916254150 6426943 7562514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.787750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.603659116
MESH:D005234 Fatty Liver Curcumin 9.3319297423
MESH:D005234 Fatty Liver Valproic Acid 9.3319224547 14986274
MESH:D005315 Fetal Diseases Valproic Acid 5.5016575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.578888407 18558336
MESH:D005355 Fibrosis Curcumin 4.4718705752
MESH:D005770 Gastrointestinal Neoplasms Curcumin 5.1818462866
MESH:D005909 Glioblastoma Curcumin 3.6917596214
MESH:D006258 Head and Neck Neoplasms Curcumin 3.8818829502 18462866
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 5.5217701891
MESH:D006849 Hydrocephalus Valproic Acid 5.4117688650
MESH:D006937 Hypercholesterolemia Curcumin 4.4318704882
MESH:D007249 Inflammation Curcumin 3.0517151092 16956363 18403477
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.3218200517 18596194
MESH:D007414 Intestinal Neoplasms Curcumin 4.5710783313
MESH:D007889 Leiomyoma Curcumin 4.9818555241
MESH:D007938 Leukemia Curcumin 3.3918462866
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 4.5816106398
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1916294345 17596541
MESH:D015458 Leukemia, T-Cell Curcumin 5.2016106398
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 2.2817355460 18705752 18006644
MESH:D008107 Liver Diseases Curcumin 2.6816956363
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.8717228818
MESH:D008175 Lung Neoplasms Curcumin 2.2816243823 19359593 18462866
MESH:D008223 Lymphoma Curcumin 3.8318462866
MESH:D016399 Lymphoma, T-Cell Curcumin 5.1816173963
MESH:D008545 Melanoma marker/mechanism 16704991
MESH:D008545 Melanoma Curcumin 2.4517885582 18462866
MESH:D008569 Memory Disorders Curcumin 4.5917263510
MESH:D008881 Migraine Disorders Valproic Acid 3.4418765137 18803445
MESH:D009101 Multiple Myeloma Curcumin 3.7619372569
MESH:D009134 Muscular Atrophy, Spinal Curcumin 5.4617962980
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.408888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3317596541
MESH:D009361 Neoplasm Invasiveness Curcumin 4.8118495463
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 5.1412497104
MESH:D009423 Nervous System Neoplasms Curcumin 6.2418462866
MESH:D009436 Neural Tube Defects Valproic Acid 3.3416359493 8888407
MESH:D009765 Obesity Curcumin 2.8119297423
MESH:D010024 Osteoporosis Curcumin 3.6718719352
MESH:D010051 Ovarian Neoplasms Curcumin 2.9018462866 19020741
MESH:D010190 Pancreatic Neoplasms Curcumin 3.0319196508 17440100 19401701
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.3720603192
MESH:D011470 Prostatic Hyperplasia Calcitriol 5.3215572423
MESH:D011471 Prostatic Neoplasms Calcitriol 3.4616644109 12479363 16289102 15754350 18247401
MESH:D011471 Prostatic Neoplasms Curcumin 3.4611398177 18156803 10851300 12497104 18226269 18769126 15129424
MESH:D019310 Pseudolymphoma Valproic Acid 5.1511422049 12752131
MESH:D011656 Pulmonary Emphysema Curcumin 4.8819168576
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 4.4318379247 10666014
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.5819155313
MESH:D012509 Sarcoma Curcumin 4.4618462866
MESH:D012559 Schizophrenia Valproic Acid 2.1015737665 19110320
MESH:D012640 Seizures Valproic Acid 2.9611738929 16876388 3137016 17978042 14763951 15475178 11044598 1511512
MESH:D018805 Sepsis Curcumin 4.3818389075
MESH:D016135 Spinal Dysraphism Valproic Acid 4.0619490988
MESH:D013226 Status Epilepticus Valproic Acid 5.1512833885
MESH:D013276 Stomach Ulcer Curcumin 3.8616631530 19188055
MESH:D014178 Translocation, Genetic Valproic Acid 5.8517262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.063119515
MESH:D001749 Urinary Bladder Neoplasms Curcumin 3.0018593936
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.138888407
MESH:D014565 Urogenital Neoplasms Curcumin 5.8018462866
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved