AutismKB 2.0

Annotation Detail for MGAT3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MGAT3 ( FLJ43371,GNT-III,GNT3,MGC141943,MGC142278 )
Gene Full Name: mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
Band: 22q13.1
Quick LinksEntrez ID:4248; OMIM: 604621; Uniprot ID:MGAT3_HUMAN; ENSEMBL ID: ENSG00000128268; HGNC ID: 7046
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00510N-Glycan biosynthesis
hsa01100Metabolic pathways
No data
Pathway IDPathway Name
200155Stabilization and expansion of the E-cadherin adherens junction
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of MGAT3 mRNAdecreases expression 18648102
D024502 alpha-Tocopherol alpha-Tocopherol results in increased expression of MGAT3 mRNAincreases expression 16908007
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MGAT3 mRNAaffects expression 16483693
C034786 bis(4-hydroxycinnamoyl)methane bis(4-hydroxycinnamoyl)methane results in increased expression of MGAT3 mRNAincreases expression 19090986
D002330 Carmustine Carmustine results in decreased expression of MGAT3 mRNAdecreases expression 15980968
D009151 Mustard Gas Mustard Gas results in increased expression of MGAT3 mRNAincreases expression 15674844
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.0218287403
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.923712494
MESH:D000544 Alzheimer Disease bis(4-hydroxycinnamoyl)methane 4.0619090986
MESH:D001249 Asthma Mustard Gas 2.7810378619
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.5411289319 1440618
MESH:D001768 Blister Mustard Gas 5.6219167455
MESH:D001932 Brain Neoplasms Carmustine 4.6916187019
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 5.6215286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 5.5017687719 10378619
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 1.777296757 3581430
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.807296757
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 2.967505956
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.3819486331 9022650
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.2112868966 2524372 8970840 11906362 18759878 14531868 11298694 8156756
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.842952479 3621924
MESH:D003924 Diabetes Mellitus, Type 2 alpha-Tocopherol 3.8116506275
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 2.039022650 18692083 11289319 18289764 18648102 8291058 16192314 9653073 6482804 9328219 1440618 7440962 6679447
MESH:D004487 Edema bis(4-hydroxycinnamoyl)methane 8.8318449507
MESH:D004487 Edema Mustard Gas 8.8311428647 9260866 11428631 11402378
MESH:D004890 Erythema Mustard Gas 5.629357497
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.173581430
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.546705139
MESH:D005909 Glioblastoma Carmustine 4.1216187019
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.397505956
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.896705139
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.3615034207
MESH:D007249 Inflammation Mustard Gas 2.929357497 9260866 11428631 11402378 11428620 11428647 8975870 16001271 17524151
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.549022650 8074119
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.236582329
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.3815034207 9327722
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.71598648 6587162 1399818 3712494
MESH:D008171 Lung Diseases Mustard Gas 3.6518702808 18161513
MESH:D008175 Lung Neoplasms alpha-Tocopherol 3.2516401635
MESH:D008175 Lung Neoplasms Mustard Gas 3.253148597 8781369
MESH:D008545 Melanoma Carmustine 2.9012393984
MESH:D009203 Myocardial Infarction alpha-Tocopherol 4.2319595682
MESH:D009361 Neoplasm Invasiveness bis(4-hydroxycinnamoyl)methane 6.1518495463
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.573581430
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.106679447
MESH:D009503 Neutropenia Mustard Gas 4.327688884 16761898
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.726482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.543988306
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.907296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.996228378
MESH:D011041 Poisoning Mustard Gas 4.1515727166
MESH:D011537 Pruritus Mustard Gas 4.5518058305
MESH:D011657 Pulmonary Eosinophilia alpha-Tocopherol 6.5114606601
MESH:D011658 Pulmonary Fibrosis Mustard Gas 3.0217720292 17266442 17620002 17894541 10334151
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.613692021
MESH:D012174 Retinitis Pigmentosa alpha-Tocopherol 4.0416849425
MESH:D012871 Skin Diseases Mustard Gas 2.7812880345 15451306 16961503
MESH:D013276 Stomach Ulcer bis(4-hydroxycinnamoyl)methane 5.2119188055
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.126587162 3712494 6582329 7505956 1399818
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.378074119
Pathway ID Pathway Name
KEGG:01100 Metabolic pathways
REACT:17015 Metabolism of proteins
KEGG:00510 N-Glycan biosynthesis
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved