AutismKB 2.0

Annotation Detail for CTAGE5


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Basic Information Top
Gene Symbol:CTAGE5 ( MEA6,MGEA,MGEA11,MGEA6 )
Gene Full Name: CTAGE family, member 5
Band: 14q21.1
Quick LinksEntrez ID:4253; OMIM: 602132; Uniprot ID:CTGE5_HUMAN; ENSEMBL ID: ENSG00000150527; HGNC ID: 7057
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D006710 Homocysteine Homocysteine results in decreased expression of CTAGE5 mRNAdecreases expression 17326132
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of CTAGE5 mRNAincreases expression 12414654
D003010 Clorgyline Clorgyline results in increased expression of CTAGE5 mRNAincreases expression 19691856
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CTAGE5 mRNAaffects cotreatment|increases expression 17942748
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of CTAGE5 mRNAincreases expression 12414654
D012402 Rotenone Rotenone results in increased expression of CTAGE5 mRNAincreases expression 19013527
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CTAGE5 mRNAaffects cotreatment|increases expression 17942748
C025643 vinclozolin vinclozolin affects the expression of CTAGE5 mRNAaffects expression 19015723
D024483 Vitamin K 3 Vitamin K 3 results in increased expression of CTAGE5 mRNAincreases expression 12414654
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.1315322242 11752688 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.2617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8514692618
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.6616835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.1411748828
MESH:D001008 Anxiety Disorders vinclozolin 3.8019015723
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.7211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.7815885639
MESH:D001321 Autistic Disorder Homocysteine 3.0316297937 20468076
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.2512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.1115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8915746008
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.6920435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.9616835633
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4716120746 18670907 18850075
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 3.6516936243
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.3416835633
MESH:D002779 Cholestasis Ethinyl Estradiol 3.0211677210 16919318 17110522 17681005 15861022 16105132 17333356
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1816354765 12621046 8697196 15668235 15340226
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.2417141729 14669216
MESH:D003324 Coronary Artery Disease Homocysteine 3.8216379339
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2610048152 15322242 20055451
MESH:D003456 Cryptorchidism vinclozolin 4.5814966744
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7117107852
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 1.5820420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9111462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.5812711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.2215322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.4212538720
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.2110568697 9294722
MESH:D017889 Exfoliation Syndrome Homocysteine 5.9916504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.1611564622
MESH:D005234 Fatty Liver Ethinyl Estradiol 3.0215345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.7111858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.2120067830
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.2216973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.6216417039
MESH:D005901 Glaucoma Homocysteine 5.5116504073
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.9110696789
MESH:D006330 Heart Defects, Congenital Homocysteine 7.2719638421
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 7.2710048152 11294989
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.5411000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.1515340226 12621046 16120746
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.3615340226 16959395 8697196 16354765 18606429
MESH:D020138 Hyperhomocysteinemia Homocysteine 4.8918234410 17292331 17369066
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9718670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 4.0716945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.6812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 7.1017937319
MESH:D007248 Infertility, Male vinclozolin 7.1016467254
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.9512200463 12878042
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.5416580747
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 4.4816518626
MESH:D007984 Leydig Cell Tumor vinclozolin 5.0216417039
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2412878042
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 1.7816984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.2212151625
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 1.2419555203 11884234
MESH:D008545 Melanoma Vitamin K 3 3.2019082730
MESH:D008591 Meningomyelocele Homocysteine 5.7916602021
MESH:D009203 Myocardial Infarction Homocysteine 3.7917412321
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.1812213967
MESH:D009410 Nerve Degeneration Rotenone 4.0417356569 15790535 18619942
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.4514600291
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.9111578682
MESH:D010212 Papilloma Hydrogen Peroxide 4.3412065085
MESH:D010300 Parkinson Disease Homocysteine 6.0816275827
MESH:D010300 Parkinson Disease Rotenone 6.0816412576 16140633 15451049 19114014 11445065 18191903 11535288 18619942 19232380
MESH:D020734 Parkinsonian Disorders Rotenone 4.2715927086 15574749 15795934 18197244
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.5712520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.8018163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 10.4611222880 11118676 11399792 11896295
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 10.4618042343 18220299 19015723
MESH:D011469 Prostatic Diseases vinclozolin 5.2218220299
MESH:D011471 Prostatic Neoplasms Clorgyline 4.2519691856
MESH:D011472 Prostatitis vinclozolin 5.2218629315
MESH:D011537 Pruritus Ethinyl Estradiol 3.6016919318 15861022
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.0818990726
MESH:D012559 Schizophrenia Homocysteine 3.1316641680
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 10.0012065085
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 10.008532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 10.0016192470
MESH:D013088 Spermatocele Ethinyl Estradiol 4.2616709447
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.8411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.3315669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.2212697716
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.5414692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.9112125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.7514671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.5715886252
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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