AutismKB 2.0

Annotation Detail for MGMT


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Basic Information Top
Gene Symbol:MGMT ( - )
Gene Full Name: O-6-methylguanine-DNA methyltransferase
Band: 10q26.3
Quick LinksEntrez ID:4255; OMIM: 156569; Uniprot ID:B4DEE8_HUMAN; ENSEMBL ID: ENSG00000170430; HGNC ID: 7059
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1739Oral cancer
1832Congenital abnormality
1904Diabetes mellitus
1934Cancer
2098Esophageal disease
Desease Name
brain tumor
colorectal cancer
CANCER
protein loss
breast cancer
Neoplasms
lung cancer
upper aerodigestive tract cancer
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C012277 1,2-diamino-4-nitrobenzene 1,2-diamino-4-nitrobenzene results in increased expression of MGMT mRNAincreases expression 17070881
C035314 1-nitropropane 1-nitropropane results in increased expression of MGMT mRNAincreases expression 17070881
C044565 2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide MGMT protein mutant form results in decreased susceptibility to [2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide co-treated with O(6)-benzylguanine]affects cotreatment|decreases response to substance 12850483
C010914 2,4-diaminotoluene 2,4-diaminotoluene results in increased expression of MGMT mRNAincreases expression 17070881
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of MGMT mRNAaffects expression 21346803
C025235 2,6-diaminotoluene 2,6-diaminotoluene results in increased expression of MGMT mRNAincreases expression 17070881
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of MGMT mRNAaffects expression 21346803
C014706 2-nitro-4-phenylenediamine 2-nitro-4-phenylenediamine results in decreased expression of MGMT mRNAdecreases expression 17070881
C019499 2-nitrofluorene 2-nitrofluorene results in increased expression of MGMT mRNAincreases expression 15890375
14600272
C016617 2-nitropropane 2-nitropropane results in increased expression of MGMT mRNAincreases expression 17070881
C029536 2-oxothiazolidine-4-carboxylic acid 2-oxothiazolidine-4-carboxylic acid results in decreased activity of MGMT proteindecreases activity 16950796
C029536 2-oxothiazolidine-4-carboxylic acid 2-oxothiazolidine-4-carboxylic acid results in increased expression of and results in increased activity of MGMT proteinincreases activity|increases expression 16950796
C029536 2-oxothiazolidine-4-carboxylic acid 2-oxothiazolidine-4-carboxylic acid results in increased expression of MGMT mRNAincreases expression 16950796
C007542 4,4'-dipyridyl disulfide 4,4'-dipyridyl disulfide binds to MGMT proteinaffects binding 12974631
C028676 4-acetylaminofluorene 4-acetylaminofluorene results in increased expression of MGMT mRNAincreases expression 17070881
C008651 4-nitrosodimethylaniline 4-nitrosodimethylaniline results in decreased expression of MGMT proteindecreases expression 15542103
C008651 4-nitrosodimethylaniline 4-nitrosodimethylaniline results in decreased expression of MGMT proteindecreases expression 15542103
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MGMT mRNAincreases expression 14600272
15890375
C105260 4-tert-octylphenol 4-tert-octylphenol results in decreased expression of MGMT mRNAdecreases expression 20965277
D000082 Acetaminophen Acetaminophen results in decreased expression of MGMT mRNAdecreases expression 12883083
D000082 Acetaminophen Acetaminophen results in increased expression of MGMT mRNAincreases expression 16751229
D000111 Acetylcysteine Acetylcysteine results in decreased activity of MGMT proteindecreases activity 16950796
D000111 Acetylcysteine Acetylcysteine results in increased expression of and results in increased activity of MGMT proteinincreases activity|increases expression 16950796
D000111 Acetylcysteine Acetylcysteine results in increased expression of MGMT mRNAincreases expression 16950796
D000171 Acrolein MGMT protein results in decreased susceptibility to Acroleindecreases response to substance 17485251
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of MGMT proteinaffects expression 20106945
D016604 Aflatoxin B1 Aflatoxin B1 results in increased expression of MGMT mRNAincreases expression 15890375
14600272
D000477 Alkylating Agents MGMT protein results in decreased susceptibility to Alkylating Agentsdecreases response to substance 15943786
16078859
C041635 alpha-carotene MGMT gene SNP affects the susceptibility to alpha-caroteneaffects response to substance 16014702
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MGMT mRNAaffects expression 16483693
D018906 Antineoplastic Agents, Alkylating MGMT protein affects the susceptibility to Antineoplastic Agents, Alkylatingaffects response to substance 15870861
16033832
C015001 arsenite arsenite results in decreased expression of MGMT mRNAdecreases expression 18929588
C015001 arsenite TRP53 protein affects the reaction [arsenite results in decreased expression of MGMT mRNA]affects reaction|decreases expression 18929588
D001205 Ascorbic Acid Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNA]affects cotreatment|decreases reaction|increases expression 18544905
D001374 Azacitidine Azacitidine results in increased expression of MGMT mRNAincreases expression 12807730
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of MGMT mRNAdecreases expression 20064835
D019207 beta Carotene MGMT gene SNP affects the susceptibility to beta Caroteneaffects response to substance 16014702
D001629 Bezafibrate Bezafibrate results in increased expression of MGMT mRNAincreases expression 15447978
C006780 bisphenol A bisphenol A results in decreased expression of MGMT mRNAdecreases expression 20965277
D019328 Buthionine Sulfoximine Buthionine Sulfoximine inhibits the reaction [MGMT protein results in increased susceptibility to Mitomycin]decreases reaction|increases response to substance 16039682
D019328 Buthionine Sulfoximine Buthionine Sulfoximine results in decreased activity of MGMT proteindecreases activity 16950796
D002087 Butyrates Butyrates results in increased expression of MGMT mRNAincreases expression 14674679
C053400 cafestol [cafestol co-treated with kahweol] results in increased activity of MGMT proteinaffects cotreatment|increases activity 12517412
C053400 cafestol cafestol results in increased activity of MGMT proteinincreases activity 12517412
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of MGMT mRNAaffects expression 17484886
D002330 Carmustine MGMT protein affects the susceptibility to Carmustineaffects response to substance 16033832
D002330 Carmustine MGMT protein mutant form results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine]affects cotreatment|decreases response to substance 15319033
D002330 Carmustine MGMT protein results in decreased susceptibility to Carmustinedecreases response to substance 15814657
15833865
16899598
16039682
D002330 Carmustine MGMT protein results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine]affects cotreatment|decreases response to substance 15319033
D002330 Carmustine MGMT protein results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine]affects cotreatment|decreases response to substance 15494421
D002713 Chlorine [Ozone co-treated with Chlorine] results in decreased expression of MGMT mRNAaffects cotreatment|decreases expression 18636392
C004656 chloroacetaldehyde MGMT protein results in decreased susceptibility to chloroacetaldehydedecreases response to substance 17485251
D002992 Clofenapate Clofenapate results in increased expression of MGMT mRNAincreases expression 12971794
D002995 Clofibric Acid Clofibric Acid results in decreased expression of MGMT mRNAdecreases expression 17602206
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of MGMT mRNAaffects cotreatment|affects expression 17602206
D003474 Curcumin Curcumin results in decreased activity of MGMT proteindecreases activity 16950796
D003474 Curcumin Curcumin results in decreased expression of MGMT mRNAdecreases expression 17596214
D003474 Curcumin Curcumin results in increased expression of and results in increased activity of MGMT proteinincreases activity|increases expression 16950796
D003474 Curcumin Curcumin results in increased expression of MGMT mRNAincreases expression 16950796
D003520 Cyclophosphamide Cyclophosphamide results in decreased expression of MGMT mRNAdecreases expression 17403535
D003520 Cyclophosphamide MGMT protein results in decreased susceptibility to Cyclophosphamidedecreases response to substance 15741301
D016572 Cyclosporine Cyclosporine results in decreased expression of MGMT mRNAdecreases expression 20106945
D003606 Dacarbazine MGMT protein affects the susceptibility to Dacarbazineaffects response to substance 14562026
D003606 Dacarbazine MGMT protein results in decreased susceptibility to Dacarbazinedecreases response to substance 15870882
10751609
12170182
D003606 Dacarbazine MGMT gene mutant form results in increased susceptibility to Dacarbazineincreases response to substance 11023546
15010317
C014347 decitabine [decitabine co-treated with trichostatin A] results in increased expression of MGMT mRNAaffects cotreatment|increases expression 15657354
C014347 decitabine decitabine promotes the reaction [HIST3H3 protein binds to MGMT promoter]affects binding|increases reaction 15657354
C014347 decitabine decitabine promotes the reaction [HIST4H4 protein binds to MGMT promoter]affects binding|increases reaction 15657354
C014347 decitabine decitabine results in decreased expression of MGMT proteindecreases expression 18021753
C014347 decitabine decitabine results in decreased methylation of MGMT promoterdecreases methylation 15703815
C014347 decitabine decitabine results in increased expression of MGMT mRNAincreases expression 15703815
15657354
19215824
D003907 Dexamethasone Dexamethasone promotes the reaction [MGMT protein results in decreased susceptibility to Nimustine]decreases response to substance|increases reaction 15481722
D003907 Dexamethasone Dexamethasone results in increased expression of MGMT mRNAincreases expression 15481722
D003907 Dexamethasone [Nimustine co-treated with Dexamethasone] results in increased expression of MGMT mRNAaffects cotreatment|increases expression 15481722
D016190 Carboplatin Carboplatin results in decreased expression of MGMT mRNAdecreases expression 18172885
D015946 Ethylene Dibromide Ethylene Dibromide binds to and results in decreased activity of MGMT proteinaffects binding|decreases activity 12151404
D015946 Ethylene Dibromide Ethylene Dibromide binds to MGMT proteinaffects binding 17226938
D015946 Ethylene Dibromide MGMT protein affects the metabolism of and results in increased activity of Ethylene Dibromideaffects metabolic processing|increases activity 14645247
D015946 Ethylene Dibromide MGMT protein results in increased activity of and results in increased susceptibility to Ethylene Dibromideincreases activity|increases response to substance 12151404
10894884
D015946 Ethylene Dibromide MGMT protein results in increased susceptibility to Ethylene Dibromideincreases response to substance 17226938
D002945 Cisplatin Cisplatin results in decreased activity of MGMT proteindecreases activity 15015788
2766459
7562019
D002945 Cisplatin Cisplatin results in decreased expression of MGMT mRNAdecreases expression 15809756
16043385
D002945 Cisplatin Cisplatin results in decreased expression of MGMT proteindecreases expression 16043385
D002945 Cisplatin MGMT protein results in decreased susceptibility to Cisplatindecreases response to substance 16043385
D002945 Cisplatin Cisplatin results in decreased activity of MGMT proteindecreases activity 15865103
C014476 diethyl maleate diethyl maleate results in decreased activity of MGMT proteindecreases activity 16950796
D004052 Diethylnitrosamine Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNA]affects cotreatment|decreases reaction|increases expression 18544905
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of MGMT mRNAaffects cotreatment|affects expression 17602206
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of MGMT mRNAincreases expression 17602206
D004052 Diethylnitrosamine [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNAaffects cotreatment|increases expression 18253720
D004052 Diethylnitrosamine [kojic acid co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNAaffects cotreatment|increases expression 18544905
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of MGMT mRNAincreases expression 15890375
D015127 9,10-Dimethyl-1,2-benzanthracene MGMT protein results in decreased susceptibility to [Methylnitrosourea co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]affects cotreatment|decreases response to substance 12663516
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of MGMT mRNAincreases expression 14600272
15890375
D004137 Dinitrochlorobenzene Dinitrochlorobenzene binds to MGMT proteinaffects binding 12974631
D004317 Doxorubicin MGMT promoter modified form results in decreased susceptibility to Doxorubicindecreases response to substance 16356834
D004391 Dust Dust results in decreased expression of MGMT mRNAdecreases expression 17805423
C045651 epigallocatechin gallate epigallocatechin gallate results in decreased methylation of MGMT promoterdecreases methylation 14633667
C045651 epigallocatechin gallate epigallocatechin gallate results in increased expression of MGMT mRNAincreases expression 15703815
14633667
D004958 Estradiol Estradiol results in decreased expression of MGMT mRNAdecreases expression 20965277
D005038 Ethylnitrosourea Ethylnitrosourea results in increased expression of MGMT mRNAincreases expression 15954086
D011345 Fenofibrate [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNAaffects cotreatment|increases expression 18253720
D015073 2-Acetylaminofluorene 2-Acetylaminofluorene results in increased expression of MGMT mRNAincreases expression 17070881
D005472 Fluorouracil Fluorouracil results in decreased expression of MGMT mRNAdecreases expression 17487405
D005472 Fluorouracil Fluorouracil results in decreased expression of MGMT proteindecreases expression 17487405
D005472 Fluorouracil MGMT protein results in decreased susceptibility to Fluorouracildecreases response to substance 17487405
D005472 Fluorouracil O(6)-benzylguanine inhibits the reaction [MGMT protein results in decreased susceptibility to Fluorouracil]decreases reaction|decreases response to substance 17487405
D005492 Folic Acid [Folic Acid co-treated with MTHFR gene SNP] affects the methylation of MGMT promoteraffects cotreatment|affects methylation 17301267
C054368 fotemustine MGMT protein results in decreased susceptibility to fotemustinedecreases response to substance 16039682
12970393
C001277 geldanamycin geldanamycin results in increased expression of and results in increased activity of MGMT proteinincreases activity|increases expression 16950796
C056507 gemcitabine gemcitabine results in decreased expression of MGMT mRNAdecreases expression 17039268
D019833 Genistein Genistein results in increased expression of MGMT mRNAincreases expression 15703815
D005978 Glutathione Glutathione affects the reaction [MGMT protein results in increased susceptibility to Mitomycin]affects reaction|increases response to substance 16039682
D017313 Fenretinide Fenretinide results in increased expression of and results in increased activity of MGMT proteinincreases activity|increases expression 16950796
D017313 Fenretinide Fenretinide results in increased expression of MGMT mRNAincreases expression 16950796
D017313 Fenretinide Fenretinide results in increased expression of MGMT proteinincreases expression 15059897
D006830 Hydralazine Hydralazine results in decreased methylation of MGMT promoterdecreases methylation 15862127
D006830 Hydralazine Hydralazine results in increased expression of MGMT mRNAincreases expression 15862127
D006918 Hydroxyurea Hydroxyurea results in increased expression of MGMT mRNAincreases expression 12929121
C051890 irinotecan MGMT mRNA results in increased susceptibility to irinotecanincreases response to substance 15239142
C053401 kahweol [cafestol co-treated with kahweol] results in increased activity of MGMT proteinaffects cotreatment|increases activity 12517412
C011890 kojic acid Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNA]affects cotreatment|decreases reaction|increases expression 18544905
C011890 kojic acid [kojic acid co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNAaffects cotreatment|increases expression 18544905
C483604 laromustine laromustine analog results in decreased activity of MGMT proteindecreases activity 14704831
C483604 laromustine MGMT protein results in decreased susceptibility to laromustine analogdecreases response to substance 14685775
C521206 lomeguatrib lomeguatrib results in decreased activity of MGMT proteindecreases activity 16278661
D008130 Lomustine MGMT mRNA results in decreased susceptibility to Lomustinedecreases response to substance 15448748
D008130 Lomustine MGMT protein affects the susceptibility to [Procarbazine co-treated with Lomustine co-treated with Vincristine]affects cotreatment|affects response to substance 16033832
D008701 Methapyrilene Methapyrilene results in increased expression of MGMT mRNAincreases expression 15890375
C008461 methyl isocyanate methyl isocyanate results in decreased activity of MGMT proteindecreases activity 14685775
D008741 Methyl Methanesulfonate MGMT protein results in decreased susceptibility to Methyl Methanesulfonatedecreases response to substance 15833865
D008769 Methylnitronitrosoguanidine MGMT protein results in decreased susceptibility to Methylnitronitrosoguanidinedecreases response to substance 16043385
D008769 Methylnitronitrosoguanidine MGMT protein results in decreased susceptibility to Methylnitronitrosoguanidinedecreases response to substance 15010311
D008770 Methylnitrosourea MGMT protein results in decreased susceptibility to Methylnitrosoureadecreases response to substance 15870882
17507295
D008770 Methylnitrosourea MGMT protein results in decreased susceptibility to [Methylnitrosourea co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]affects cotreatment|decreases response to substance 12663516
D008770 Methylnitrosourea Methylnitrosourea results in increased expression of MGMT mRNAincreases expression 20965277
D008770 Methylnitrosourea MGMT protein affects the reaction [Methylnitrosourea results in increased activity of CASP3 protein]affects reaction|increases activity 13679151
D008770 Methylnitrosourea MGMT protein inhibits the reaction [TRP53 gene mutant form results in increased susceptibility to Methylnitrosourea]decreases reaction|increases response to substance 11536039
D008770 Methylnitrosourea MGMT protein results in decreased susceptibility to Methylnitrosoureadecreases response to substance 13679151
11536039
11276365
D008770 Methylnitrosourea MLH1 affects the reaction [MGMT protein affects the reaction [Methylnitrosourea results in increased activity of CASP3 protein]]affects reaction|increases activity 13679151
D008770 Methylnitrosourea MLH1 protein promotes the reaction [MGMT protein results in decreased susceptibility to Methylnitrosourea]decreases response to substance|increases reaction 13679151
D016685 Mitomycin Buthionine Sulfoximine inhibits the reaction [MGMT protein results in increased susceptibility to Mitomycin]decreases reaction|increases response to substance 16039682
D016685 Mitomycin Glutathione affects the reaction [MGMT protein results in increased susceptibility to Mitomycin]affects reaction|increases response to substance 16039682
D016685 Mitomycin MGMT protein results in increased susceptibility to Mitomycinincreases response to substance 16039682
C040369 mitozolomide MGMT protein affects the susceptibility to mitozolomideaffects response to substance 10880022
C040369 mitozolomide MGMT protein results in decreased susceptibility to mitozolomidedecreases response to substance 10355819
10022554
D015376 Nimustine Dexamethasone promotes the reaction [MGMT protein results in decreased susceptibility to Nimustine]decreases response to substance|increases reaction 15481722
D015376 Nimustine MGMT protein results in decreased susceptibility to Nimustinedecreases response to substance 15809756
D015376 Nimustine [Nimustine co-treated with Dexamethasone] results in increased expression of MGMT mRNAaffects cotreatment|increases expression 15481722
D015376 Nimustine Nimustine results in increased expression of MGMT mRNAincreases expression 15481722
D015376 Nimustine MGMT gene mutant form results in increased susceptibility to Nimustineincreases response to substance 11023546
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of MGMT mRNAincreases expression 17616710
C403290 O(6)-(4-bromothenyl)guanine MGMT protein mutant form results in decreased susceptibility to [O(6)-(4-bromothenyl)guanine co-treated with temozolomide]affects cotreatment|decreases response to substance 16075413
C403290 O(6)-(4-bromothenyl)guanine O(6)-(4-bromothenyl)guanine inhibits the reaction [MGMT protein results in decreased susceptibility to temozolomide]decreases reaction|decreases response to substance 15486188
C403290 O(6)-(4-bromothenyl)guanine O(6)-(4-bromothenyl)guanine results in decreased activity of MGMT proteindecreases activity 15486188
16075413
15831531
C064976 O(6)-benzylguanine MGMT protein mutant form results in decreased susceptibility to [2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide co-treated with O(6)-benzylguanine]affects cotreatment|decreases response to substance 12850483
C064976 O(6)-benzylguanine MGMT protein mutant form results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine]affects cotreatment|decreases response to substance 15319033
C064976 O(6)-benzylguanine MGMT protein mutant form results in decreased susceptibility to [O(6)-benzylguanine co-treated with temozolomide]affects cotreatment|decreases response to substance 15319033
C064976 O(6)-benzylguanine MGMT protein results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine]affects cotreatment|decreases response to substance 15319033
C064976 O(6)-benzylguanine MGMT protein results in decreased susceptibility to [O(6)-benzylguanine co-treated with temozolomide]affects cotreatment|decreases response to substance 15319033
C064976 O(6)-benzylguanine O(6)-benzylguanine analog results in decreased activity of MGMT proteindecreases activity 15993610
C064976 O(6)-benzylguanine O(6)-benzylguanine inhibits the reaction [MGMT protein results in decreased susceptibility to Fluorouracil]decreases reaction|decreases response to substance 17487405
C064976 O(6)-benzylguanine O(6)-benzylguanine results in decreased activity of MGMT proteindecreases activity 15615536
15814657
16075413
15735757
15634019
15993610
16043385
C064976 O(6)-benzylguanine O(6)-benzylguanine results in decreased activity of MGMT proteindecreases activity 15010311
C064976 O(6)-benzylguanine MGMT protein results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine]affects cotreatment|decreases response to substance 15494421
C064976 O(6)-benzylguanine MGMT protein results in decreased susceptibility to [O(6)-benzylguanine co-treated with temozolomide]affects cotreatment|decreases response to substance 15494421
C064976 O(6)-benzylguanine O(6)-benzylguanine results in decreased activity of MGMT proteindecreases activity 11751525
C026209 oltipraz oltipraz results in increased expression of and results in increased activity of MGMT proteinincreases activity|increases expression 16950796
C026209 oltipraz oltipraz results in increased expression of MGMT mRNAincreases expression 16950796
D010126 Ozone [Ozone co-treated with Chlorine] results in decreased expression of MGMT mRNAaffects cotreatment|decreases expression 18636392
D017239 Paclitaxel Paclitaxel results in increased expression of MGMT mRNAincreases expression 12929121
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of MGMT mRNA]affects reaction|decreases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of MGMT mRNAdecreases expression 19482888
D010672 Phenytoin Phenytoin results in increased methylation of MGMT promoterincreases methylation 15949900
D010882 Piperonyl Butoxide Piperonyl Butoxide results in increased expression of MGMT mRNAincreases expression 15890375
C006253 pirinixic acid pirinixic acid results in increased expression of MGMT mRNAincreases expression 15890375
D011344 Procarbazine MGMT protein affects the susceptibility to [Procarbazine co-treated with Lomustine co-treated with Vincristine]affects cotreatment|affects response to substance 16033832
D011886 Radon Radon results in increased methylation of MGMT promoterincreases methylation 16902270
C059514 resveratrol resveratrol results in increased expression of and results in increased activity of MGMT proteinincreases activity|increases expression 16950796
C440975 silybin silybin results in increased expression of and results in increased activity of MGMT proteinincreases activity|increases expression 16950796
D012838 Silymarin Silymarin results in decreased activity of MGMT proteindecreases activity 16950796
D012838 Silymarin Silymarin results in increased expression of and results in increased activity of MGMT proteinincreases activity|increases expression 16950796
D012838 Silymarin Silymarin results in increased expression of MGMT mRNAincreases expression 16950796
C017947 sodium arsenite sodium arsenite results in decreased expression of MGMT mRNAdecreases expression 12760830
C017947 sodium arsenite sodium arsenite results in increased expression of MGMT mRNAincreases expression 11241755
D013311 Streptozocin MGMT protein results in decreased susceptibility to Streptozocindecreases response to substance 16039682
C016766 sulforafan sulforafan results in increased expression of and results in increased activity of MGMT proteinincreases activity|increases expression 16950796
D013629 Tamoxifen Tamoxifen results in decreased expression of MGMT mRNAdecreases expression 20965277
C047246 temozolomide MGMT protein affects the susceptibility to temozolomideaffects response to substance 15865885
C047246 temozolomide MGMT protein mutant form results in decreased susceptibility to [O(6)-(4-bromothenyl)guanine co-treated with temozolomide]affects cotreatment|decreases response to substance 16075413
C047246 temozolomide MGMT protein mutant form results in decreased susceptibility to [O(6)-benzylguanine co-treated with temozolomide]affects cotreatment|decreases response to substance 15319033
C047246 temozolomide MGMT protein results in decreased susceptibility to [O(6)-benzylguanine co-treated with temozolomide]affects cotreatment|decreases response to substance 15319033
C047246 temozolomide MGMT protein results in decreased susceptibility to temozolomidedecreases response to substance 15833865
15758010
16039682
15814657
C047246 temozolomide O(6)-(4-bromothenyl)guanine inhibits the reaction [MGMT protein results in decreased susceptibility to temozolomide]decreases reaction|decreases response to substance 15486188
C047246 temozolomide MGMT protein inhibits the reaction [temozolomide results in increased mutagenesis of HPRT1 gene]decreases reaction|increases mutagenesis 17116724
C047246 temozolomide MGMT protein results in decreased susceptibility to [O(6)-benzylguanine co-treated with temozolomide]affects cotreatment|decreases response to substance 15494421
D013755 Tetradecanoylphorbol Acetate MGMT protein results in decreased susceptibility to [Methylnitrosourea co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]affects cotreatment|decreases response to substance 12663516
D014226 Triazenes Triazenes analog results in decreased activity of MGMT proteindecreases activity 15615536
C012589 trichostatin A [decitabine co-treated with trichostatin A] results in increased expression of MGMT mRNAaffects cotreatment|increases expression 15657354
D014750 Vincristine MGMT protein affects the susceptibility to [Procarbazine co-treated with Lomustine co-treated with Vincristine]affects cotreatment|affects response to substance 16033832
D014752 Vinyl Chloride Vinyl Chloride results in decreased expression of MGMT proteindecreases expression 15256147
D015032 Zinc Zinc binds to and results in increased activity of and results in increased stability of MGMT proteinaffects binding|increases activity|increases stability 12549918
D015032 Zinc Zinc binds to and results in increased activity of MGMT proteinaffects binding|increases activity 12974631
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.6114745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 5.896195326
MESH:D000014 Abnormalities, Drug-Induced Phenytoin 5.896195326 9677735 9118846 8986270 10563481 3425630
MESH:D000138 Acidosis Ammonium Chloride 2.6418287403
MESH:D000140 Acidosis, Lactic methyl isocyanate 5.808440870
MESH:D000169 Acrodermatitis Zinc 4.4816889938 17190629 17202136
MESH:D058186 Acute Kidney Injury Cisplatin 9.7515814532 17670903 12690470
MESH:D058186 Acute Kidney Injury Folic Acid 9.7516316344 17003819 16595132
MESH:D058186 Acute Kidney Injury resveratrol 9.7516538975
MESH:D055371 Acute Lung Injury Acrolein 10.4721297076 20525806
MESH:D055371 Acute Lung Injury Chlorine 10.4720601635
MESH:D055371 Acute Lung Injury pirinixic acid 10.4718653653
MESH:D000230 Adenocarcinoma 9,10-Dimethyl-1,2-benzanthracene 28.2310697514 12844480
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 28.2320127859 20464547
MESH:D000230 Adenocarcinoma Cisplatin 28.2317638652 11798837
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 28.2316033868
MESH:D000230 Adenocarcinoma Doxorubicin 28.2317418594
MESH:D000230 Adenocarcinoma Estradiol 28.2311473722
MESH:D000230 Adenocarcinoma Fenretinide 28.2310697514
MESH:D000230 Adenocarcinoma Fluorouracil 28.2317638652
MESH:D000230 Adenocarcinoma Genistein 28.2311473722
MESH:D000230 Adenocarcinoma Methylnitrosourea 28.2315688392 15113128
MESH:D000230 Adenocarcinoma Vincristine 28.2319825857
MESH:D000236 Adenoma 2-Acetylaminofluorene 30.5410737359
MESH:D000236 Adenoma 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 30.5416176798
MESH:D000236 Adenoma 9,10-Dimethyl-1,2-benzanthracene 30.5411376689
MESH:D000236 Adenoma Benzo(a)pyrene 30.546695378
MESH:D000236 Adenoma Diethylnitrosamine 30.546695378 10737359
MESH:D000236 Adenoma Dimethylnitrosamine 30.5419555203
MESH:D000236 Adenoma Ethylnitrosourea 30.546695378
MESH:D000236 Adenoma Folic Acid 30.5416963246
MESH:D000236 Adenoma resveratrol 30.5415688382
MESH:D002759 Adenoma, Bile Duct 2-Acetylaminofluorene 5.076705139
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 12.0617620307 18056438 19061943 17162532 19052882 16434500
MESH:D018248 Adenoma, Liver Cell Phenobarbital 12.0617620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 12.0616434500
MESH:D011125 Adenomatous Polyposis Coli sulforafan 4.4517942926
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.7615276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 3.9617306315 16712894
MESH:D000419 Albuminuria Doxorubicin 3.6621441931
MESH:D019973 Alcohol-Related Disorders Curcumin 4.1417887948
MESH:D000544 Alzheimer Disease Acrolein 11.4617570602 14715435 15207723
MESH:D000544 Alzheimer Disease Curcumin 11.4615590663
MESH:D000544 Alzheimer Disease Folic Acid 11.4617116317
MESH:D000544 Alzheimer Disease Ozone 11.4615513908
MESH:D000544 Alzheimer Disease resveratrol 11.4616162502 16183991
MESH:D000544 Alzheimer Disease Zinc 11.4616410023 17119284 16325427 16580781
MESH:D000686 Amyloidosis Diethylstilbestrol 3.6015469931
MESH:D000740 Anemia Fluorouracil 2.9016511603 17963324 15504547
MESH:D000755 Anemia, Sickle Cell Zinc 4.0116916123
MESH:D000799 Angioedema Acetaminophen 2.9110982225
MESH:D001005 Anus Neoplasms Dacarbazine 5.3512170190
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.1719183758
MESH:D001161 Arteriosclerosis Acrolein 7.7515014928
MESH:D001161 Arteriosclerosis Cyclophosphamide 7.7515014928
MESH:D001169 Arthritis, Experimental Dexamethasone 5.5117659584
MESH:D001169 Arthritis, Experimental resveratrol 5.5117115116
MESH:D001172 Arthritis, Rheumatoid Curcumin 3.7216807698
MESH:D001172 Arthritis, Rheumatoid Ozone 3.7215570426
MESH:D001249 Asthma epigallocatechin gallate 5.7416516891
MESH:D001249 Asthma Ozone 5.7416373670 17854713
MESH:D001249 Asthma Zinc 5.7417085522
MESH:D001254 Astrocytoma temozolomide 5.5615865885
MESH:D050197 Atherosclerosis Acrolein 10.5517363696 16126721 16037261
MESH:D050197 Atherosclerosis Curcumin 10.5518704882
MESH:D050197 Atherosclerosis Phenytoin 10.5515136057
MESH:D050197 Atherosclerosis resveratrol 10.5516873680 17967414
MESH:D001321 Autistic Disorder Acetaminophen 2.1318445737
MESH:D001321 Autistic Disorder Folic Acid 2.1321388746
MESH:D001321 Autistic Disorder Glutathione 2.1316917939 19267885 18929414 19056591
MESH:D001327 Autoimmune Diseases Curcumin 13.1419761891
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 13.1419761891
MESH:D001327 Autoimmune Diseases sulforafan 13.1419761891
MESH:D001661 Biliary Tract Neoplasms Vinyl Chloride 5.9211024202
MESH:D001778 Blood Coagulation Disorders pirinixic acid 2.3119483382
MESH:D019046 Bone Marrow Neoplasms Cisplatin 8.9414601052
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 8.9414601052
MESH:D001859 Bone Neoplasms Paclitaxel 3.7115867366
MESH:D001862 Bone Resorption bisphenol A 3.0311985600
MESH:D001927 Brain Diseases Ethylnitrosourea 4.0514991843
MESH:D001930 Brain Injuries Zinc 3.7917109824
MESH:D002545 Brain Ischemia alpha-carotene 16.9416157235
MESH:D002545 Brain Ischemia beta Carotene 16.9416157235
MESH:D002545 Brain Ischemia Curcumin 16.9416770732
MESH:D002545 Brain Ischemia resveratrol 16.9417600658
MESH:D001932 Brain Neoplasms Carmustine 23.4016187019
MESH:D001932 Brain Neoplasms Curcumin 23.4017596214
MESH:D001932 Brain Neoplasms Doxorubicin 23.4017150277
MESH:D001932 Brain Neoplasms Ethylnitrosourea 23.4016651633 15144691 16357521 16436596 18412241
MESH:D001932 Brain Neoplasms Fenretinide 23.4016187019
MESH:D001932 Brain Neoplasms Vinyl Chloride 23.4012562636
MESH:D001943 Breast Neoplasms 2,4-diaminotoluene 29.4511921183
MESH:D001943 Breast Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 29.4520146248
MESH:D001943 Breast Neoplasms 9,10-Dimethyl-1,2-benzanthracene 29.4517127718 18840765 15565634 20435547 16153821
MESH:D001943 Breast Neoplasms Ascorbic Acid 29.4516443354
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 29.4520146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 29.4517123778
MESH:D001943 Breast Neoplasms Cisplatin 29.4518382427 19526202
MESH:D001943 Breast Neoplasms Curcumin 29.4518593918 18462866 16243823 19250217
MESH:D001943 Breast Neoplasms Cyclophosphamide 29.4518234424 12006526 17388661 17020986 11325840 16978400 18323546 15136595 15093573
MESH:D001943 Breast Neoplasms Dacarbazine 29.4517983394
MESH:D001943 Breast Neoplasms decitabine 29.4519208741 18320071
MESH:D001943 Breast Neoplasms Diethylnitrosamine 29.4517474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 29.4517129689 15324884
MESH:D001943 Breast Neoplasms Doxorubicin 29.4516264153 18382427 15939500 17369602 16096432 16322301 18628466 16595493 19526202 16935488 18695136 15692762 16115903 16826403 11325840 15668708 15634643 15993339 18234424 15994142 15567936 17983394 17426702 15136595
MESH:D001943 Breast Neoplasms Estradiol 29.4518497071 17261762 17018787 16675129 12948864 14630087 17289903 19861407
MESH:D001943 Breast Neoplasms Ethylene Dibromide 29.4511921183
MESH:D001943 Breast Neoplasms Fenretinide 29.4516601279
MESH:D001943 Breast Neoplasms Fluorouracil 29.4515136595 16557594 18357371 18608205 19217205 16595493 16110121
MESH:D001943 Breast Neoplasms Folic Acid 29.4516777985
MESH:D001943 Breast Neoplasms gemcitabine 29.4518382427 17039268
MESH:D001943 Breast Neoplasms Genistein 29.4516873071 17200150 16541309
MESH:D001943 Breast Neoplasms Methylnitrosourea 29.4516253758 14633655 11306469
MESH:D001943 Breast Neoplasms Paclitaxel 29.4515136595 16115903 18323546 11325840 16244791 18223236 16273361 18234424
MESH:D001943 Breast Neoplasms Procarbazine 29.4511921183
MESH:D001943 Breast Neoplasms resveratrol 29.4517534123 17651959 16393696
MESH:D001943 Breast Neoplasms Tamoxifen 29.4519155303 18425577 20135344 21152245 15565566 18984771 16202921 19200415 17242785 17261762 11161223 17440819 19221464 20065188 19189212 16873071 16273361 17049068 18815881 18821012 17893378 19244106 18629630 19289846 18855134 20390343 19115204 19288272 18351453 20859285 19189210 19059307 19142967 16818667 20544844 21138602 19084267 19103187 19011961 20005174 15668708 18997820 19066611 19487384 19410462
MESH:D016535 Bronchial Hyperreactivity Ozone 2.9219059883 18315731 17626835 15516495 14754758 18417511 16777450
MESH:D002100 Cachexia Ozone 3.8216183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.5416111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 2.8810355542 15721981 16192424 15700767 16050911 18705752 16097048 16227642 16011737 15673190 16124888 3786805
MESH:D002276 Carcinoid Tumor Dacarbazine 23.2616051944
MESH:D002276 Carcinoid Tumor Doxorubicin 23.2616051944
MESH:D002276 Carcinoid Tumor Fluorouracil 23.2616051944
MESH:D002276 Carcinoid Tumor Streptozocin 23.2616051944
MESH:D002277 Carcinoma Curcumin 9.7018593918
MESH:D002277 Carcinoma Dimethylnitrosamine 9.7019555203
MESH:D002277 Carcinoma Fluorouracil 9.7017121937
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.6019066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 49.8916705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 49.8916705839
MESH:D006528 Carcinoma, Hepatocellular 2-Acetylaminofluorene 49.893084413 3581430 6705139 10737359 17761372
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 49.893084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 49.8921507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 49.8918788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 49.8917982673
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 49.8919701751
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 49.8916328049 18494052 19919837 19519916 17138121 16807293 19208518 3581430 18665156 18978308 10737359 19394651 17978847 19335982 10672840 16540662 18056438 18506893 19052882 20512989 18393292 20084675 17173139 18785209 19539802 21159647 20214788 19701751 20727157 17162532 16935385 20524982 16288022 16830150 19171122 20101231 18210153 19822196 20514400 17428255 18788625 20007298 20432363 16698587 16502159 20935162 16878318 19383236 18971187 19107877 16569478 16779866 17761372 11831363 19418558 16681979 17055752 18691550 3084413
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 49.8916924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 49.8916023760 18059187 16234567 17876044
MESH:D006528 Carcinoma, Hepatocellular Estradiol 49.8916924424
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 49.8917159502 16270382
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 49.8917045692 17088986 17971768 16332177 18930000 16799960
MESH:D006528 Carcinoma, Hepatocellular Genistein 49.8916924424
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 49.8916313753
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 49.8920007298 1701930 6705139 17173139 20935162
MESH:D006528 Carcinoma, Hepatocellular resveratrol 49.8919321006 16227395
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 49.8915276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 49.8916924424
MESH:D006528 Carcinoma, Hepatocellular Vinyl Chloride 49.8910699891 12958735 15289165 12828392
MESH:D002278 Carcinoma in Situ bisphenol A 4.0617123778
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 8.4316152834
MESH:D018827 Carcinoma, Lewis Lung resveratrol 8.4316675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung Carboplatin 6.5916685392
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 6.5912023789 16685392
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 6.5918414057
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 14.4716201981
MESH:D002292 Carcinoma, Renal Cell Dacarbazine 14.4716201981
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 14.4716201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 14.4718695887
MESH:D002292 Carcinoma, Renal Cell Vincristine 14.4716201981
MESH:D002294 Carcinoma, Squamous Cell 9,10-Dimethyl-1,2-benzanthracene 48.2311376689
MESH:D002294 Carcinoma, Squamous Cell Acetylcysteine 48.2317015178
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 48.2320419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 48.2317066447 6189445 18337622
MESH:D002294 Carcinoma, Squamous Cell Curcumin 48.2318462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 48.2319215824
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 48.2316033868
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 48.236189445
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 48.2316274795
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 48.2316757204 18986760 17066447 16280240
MESH:D002294 Carcinoma, Squamous Cell Glutathione 48.2317015178
MESH:D002294 Carcinoma, Squamous Cell resveratrol 48.2316227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 48.2318572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 48.2318922899
MESH:D002294 Carcinoma, Squamous Cell Vincristine 48.236189445
MESH:D002294 Carcinoma, Squamous Cell Zinc 48.2316543248
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 2.7917572228
MESH:D009202 Cardiomyopathies Doxorubicin 2.8617007740 18627295 17928571 15476868 17974986 17519947 16278810 17131338 15811867 17308081 15505089 16364871 15792986 16612575 17382496 16651473 16242529 17351982 17924179 17329180 16952015 16731534 16455267 16269455 16109756
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.5316243910 17334414
MESH:D002318 Cardiovascular Diseases Folic Acid 11.6516755160
MESH:D002318 Cardiovascular Diseases Genistein 11.6516332659
MESH:D002318 Cardiovascular Diseases resveratrol 11.6515458977
MESH:D002318 Cardiovascular Diseases Zinc 11.6516936243
MESH:D002386 Cataract Acetaminophen 5.4510977129
MESH:D002386 Cataract Methylnitrosourea 5.4512484553
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 29.286135515
MESH:D002471 Cell Transformation, Neoplastic Acetylcysteine 29.2818226522
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 29.2812371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 29.2817174075 21159647 2727394 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 29.2818566989
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 29.2816003739
MESH:D002471 Cell Transformation, Neoplastic Methylnitronitrosoguanidine 29.282727394
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 29.282727394 7505956
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 29.2820056578 19524636
MESH:D002493 Central Nervous System Diseases Phenobarbital 8.674080065
MESH:D002493 Central Nervous System Diseases Phenytoin 8.674080065
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 5.0417160924
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 4.5516154183
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 2.8819052882
MESH:D002779 Cholestasis Cyclosporine 5.3219486331
MESH:D002779 Cholestasis pirinixic acid 5.3219176532
OMIM:601042 CHOREOATHETOSIS/SPASTICITY, EPISODIC Phenytoin 4.9411748493
MESH:D002971 Cleft Lip Folic Acid 6.1321254359
MESH:D002971 Cleft Lip Phenytoin 6.132227380
MESH:D002972 Cleft Palate Folic Acid 5.038946559 21254359
MESH:D002972 Cleft Palate Phenytoin 5.033877104 2227380 6862529 10789828 1687470 6856622
MESH:D003092 Colitis Curcumin 6.8216782535 16804969 18200517
MESH:D003092 Colitis resveratrol 6.8216474422
MESH:D003093 Colitis, Ulcerative Dinitrochlorobenzene 3.4419159591 17373747
MESH:D003103 Coloboma Curcumin 8.5218809619
MESH:D003103 Coloboma Phenytoin 8.529212184
MESH:D003110 Colonic Neoplasms arsenite 18.1115037631
MESH:D003110 Colonic Neoplasms Butyrates 18.1115936596
MESH:D003110 Colonic Neoplasms Curcumin 18.1116340194 19359593
MESH:D003110 Colonic Neoplasms decitabine 18.1117616700
MESH:D003110 Colonic Neoplasms Dexamethasone 18.1115824018
MESH:D003110 Colonic Neoplasms Fluorouracil 18.1118772588 17725105 17169374 16510598 17018589 15001691 17287894 17016597 17172411 16340194
MESH:D003110 Colonic Neoplasms Genistein 18.1117182828
MESH:D003110 Colonic Neoplasms irinotecan 18.1117287894 17725105
MESH:D003110 Colonic Neoplasms resveratrol 18.1116338953
MESH:D015179 Colorectal Neoplasms Acrolein 18.0917597105
MESH:D015179 Colorectal Neoplasms Azacitidine 18.0919934284
MESH:D015179 Colorectal Neoplasms Cisplatin 18.0915273666
MESH:D015179 Colorectal Neoplasms Dacarbazine 18.0915273666
MESH:D015179 Colorectal Neoplasms decitabine 18.0918981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 18.0918259882 18802399
MESH:D015179 Colorectal Neoplasms Fenretinide 18.0917273769
MESH:D015179 Colorectal Neoplasms Fluorouracil 18.0916303861 17255274 17401013 18448328 16282729 16391804 16331619 17094418 18802399 18949393 18383874 18288408 18509181 14970324 17695437 17594712 16524972 15148649 20501625 17016601 17454858 15289873
MESH:D015179 Colorectal Neoplasms Folic Acid 18.0917087956 17116713 16963246 16985020 17245555
MESH:D015179 Colorectal Neoplasms irinotecan 18.0917454858 16391804 15273666 17159606 16303861 18259882 18509181
MESH:D015179 Colorectal Neoplasms Paclitaxel 18.0918802399
MESH:D015179 Colorectal Neoplasms resveratrol 18.0916550006
MESH:D003139 Common Cold Ascorbic Acid 4.5417323712
MESH:D000013 Congenital Abnormalities Phenytoin 3.9010627286
MESH:D016510 Corneal Neovascularization Curcumin 3.9918497527
MESH:D003327 Coronary Disease resveratrol 3.0816507316
MESH:D019465 Craniofacial Abnormalities Dexamethasone 3.1717728286
MESH:D019465 Craniofacial Abnormalities Phenytoin 3.178986270 19952982 9212184
MESH:D019465 Craniofacial Abnormalities Zinc 3.1719302082
MESH:D003456 Cryptorchidism Diethylstilbestrol 3.6716002989 12952375
MESH:D003490 Cyanosis 2,4-dinitrotoluene 7.9018551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 7.9018551238
MESH:D003550 Cystic Fibrosis Acetylcysteine 6.5019747007
MESH:D003550 Cystic Fibrosis Glutathione 6.5019747007
MESH:D003556 Cystitis Acrolein 8.9812161096
MESH:D003556 Cystitis Cyclophosphamide 8.9816413132 18483878 15276878 16989017 15643279 18372110 18093676 17010015 12913760 18710439 18433785 18295254 16614059 12388444 10498854 17979934 12161096 16651033 10700343 11948286
MESH:D007644 Darier Disease Fluorouracil 3.8716733453
MESH:D003711 Demyelinating Diseases Tamoxifen 3.4619031437
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 4.7112438553
MESH:D017449 Dermatitis, Allergic Contact Dinitrochlorobenzene 4.7115491423
MESH:D003876 Dermatitis, Atopic pirinixic acid 1.9018249437
MESH:D009783 Dermatitis, Occupational Vinyl Chloride 4.7810870345
MESH:D003920 Diabetes Mellitus Streptozocin 7.0716285004
MESH:D003920 Diabetes Mellitus Zinc 7.0716479319
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 9.6315331540 11751995 10990075
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 9.6316873680
MESH:D003921 Diabetes Mellitus, Experimental Streptozocin 9.6319960420 19586609 19496084 12446591 7637645 19298542 16286809 6379147 16684804 11055810 8740154 2177838 18603373 17874149 15862027 15831366 18715473 12644472 15298345 11260395 12093613 12083368 17442507 1374869
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 4.7218772604
MESH:D003922 Diabetes Mellitus, Type 1 Streptozocin 4.7218603373
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 15.5016506275
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 15.5018403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 15.5020387270
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 15.5016988119
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 15.5016886840
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 15.5016647724
MESH:D003924 Diabetes Mellitus, Type 2 Streptozocin 15.5019586609 19647726
MESH:D058065 Diabetic Cardiomyopathies Streptozocin 4.8016025228
MESH:D003928 Diabetic Nephropathies Curcumin 19.6418204486
MESH:D003928 Diabetic Nephropathies Estradiol 19.6419279558
MESH:D003928 Diabetic Nephropathies resveratrol 19.6416286809
MESH:D003928 Diabetic Nephropathies Streptozocin 19.6419682444 19960420
MESH:D003928 Diabetic Nephropathies Tamoxifen 19.6419279558
MESH:D003930 Diabetic Retinopathy Streptozocin 4.5417662242
MESH:D003967 Diarrhea Dexamethasone 2.867237001
OMIM:607208 DRAVET SYNDROME Phenytoin 4.4811748493
MESH:D003875 Drug Eruptions Phenytoin 4.5915024534
MESH:D004342 Drug Hypersensitivity Dacarbazine 4.3216508601
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 23.6421346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 23.6418551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2-nitropropane 23.6416445897 15804453 20517888
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 23.6414986274 11739529 16081117 12392966 16227642 19164858 10915739 2444490 19923254 16485898 18071297 14550746 16109766 10774834 17906064 19420014 11834606 12540782 15619225 11743745 11421492 10663392 16177239 14725611 12958197 17562736 17522070 11461765 12705907 16781746 15968718 19416960 19085960 19370779 19739265 12153990 11287661 16393943 11529661 12594235 18713872
MESH:D056486 Drug-Induced Liver Injury Acetylcysteine 23.6411287661
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 23.643786805 21278145 19336974 7440962 15998439 16227642 11566570 2869522 6623471 10915739 3732212 16177239 7179309 9327722 10092053 6884620 15968718 19085960 15027814 4309450 7120509 17522070
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 23.6419107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 23.648172417
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 23.6417416283
MESH:D056486 Drug-Induced Liver Injury Ethylene Dibromide 23.642862719
MESH:D056486 Drug-Induced Liver Injury Silymarin 23.6414998559
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.1619426721
MESH:D004362 Drug Toxicity Cisplatin 6.0712231392 15033597 19839026 12649298
MESH:D004362 Drug Toxicity Doxorubicin 6.0718602426
MESH:D004381 Duodenal Ulcer Curcumin 3.1817351913
MESH:D050171 Dyslipidemias Fenofibrate 3.7016707586
MESH:D004417 Dyspnea Chlorine 3.7020016425
MESH:D004421 Dystonia Phenobarbital 3.141851702
MESH:C538011 Eales disease Ascorbic Acid 4.549068938
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 5.0418357618
MESH:D004485 Eczema Dexamethasone 3.5812438553
MESH:D004487 Edema Dexamethasone 9.7819703484
MESH:D004487 Edema pirinixic acid 9.7812083418
MESH:D004487 Edema resveratrol 9.788985016
MESH:D004487 Edema Tetradecanoylphorbol Acetate 9.7811698051 8113982 7812673 8273558 16716910 9599246 15177302
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Phenytoin 10.4917654737
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 10.4917872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 10.4919031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 10.9119294695
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 10.9119294695
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 8.8316402032
MESH:D004714 Endometrial Hyperplasia Genistein 8.8316402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 24.7715700306 16804899
MESH:D016889 Endometrial Neoplasms Doxorubicin 24.7717359293
MESH:D016889 Endometrial Neoplasms Estradiol 24.7718566989 19148513 11473722
MESH:D016889 Endometrial Neoplasms Fenofibrate 24.7716569247
MESH:D016889 Endometrial Neoplasms Folic Acid 24.7717301261
MESH:D016889 Endometrial Neoplasms Genistein 24.7711473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 24.7717893378 20544844 16202921 19155303
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.2218037988
MESH:D020345 Enterocolitis, Necrotizing resveratrol 3.9417923197
MESH:D004802 Eosinophilia Cyclophosphamide 3.3411006010
MESH:D004816 Epidermal Necrolysis, Toxic Phenytoin 4.3120235791
MESH:D004820 Epidermolysis Bullosa Phenytoin 5.296251365 1399206
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.213659116
MESH:D004828 Epilepsies, Partial Phenobarbital 7.253922381 11558140
MESH:D004828 Epilepsies, Partial Phenytoin 7.2517116037 11558140
MESH:D004827 Epilepsy Phenobarbital 5.1120417680
MESH:D004827 Epilepsy Phenytoin 5.11821787 11434505 20417680
MESH:D004832 Epilepsy, Absence Phenobarbital 2.756401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 8.677750514
MESH:D017029 Epilepsy, Complex Partial Phenytoin 8.677750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 7.803659116
MESH:D004830 Epilepsy, Tonic-Clonic Phenytoin 7.803659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.1716302075
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 15.6116530937
MESH:D004938 Esophageal Neoplasms Cisplatin 15.6117638652 15173087 16785472 15464296 16481741
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 15.6117016578
MESH:D004938 Esophageal Neoplasms Fluorouracil 15.6116337965 16785472 15173087 17638652 16481741
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 15.6115547721 16704527 15150132 15878914 16805852 15264214 15623463 16510608 15547733
MESH:D004938 Esophageal Neoplasms Paclitaxel 15.6116481741
MESH:D004938 Esophageal Neoplasms Zinc 15.6116543248
MESH:D017889 Exfoliation Syndrome Folic Acid 4.5716504073
MESH:D005234 Fatty Liver arsenite 28.7818296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 28.7812795759 15959796 12631006 16239168 19224547 16045604 17595544 61145
MESH:D005234 Fatty Liver Curcumin 28.7819297423
MESH:D005234 Fatty Liver Cyclosporine 28.7819224547
MESH:D005234 Fatty Liver Diethylnitrosamine 28.7820387270 21071580
MESH:D005234 Fatty Liver pirinixic acid 28.7819236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 28.7819224547 14986274
MESH:D005234 Fatty Liver Vinyl Chloride 28.7812197357
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 6.0516513791 16002989 16534752 15751030 16611131
MESH:D052776 Female Urogenital Diseases Tamoxifen 6.0516709447
MESH:D005313 Fetal Death Phenytoin 4.2010627286
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.6014745880
MESH:D018222 Fibromatosis, Aggressive Dacarbazine 14.3519069698
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 14.3519069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 14.3519069698
MESH:D005354 Fibrosarcoma Methylnitrosourea 4.3111555667
MESH:D005355 Fibrosis arsenite 13.9118296743
MESH:D005355 Fibrosis Carbon Tetrachloride 13.9118705752
MESH:D005355 Fibrosis Curcumin 13.9118705752
MESH:D005355 Fibrosis Cyclosporine 13.9112168785 12639820
MESH:D005739 Gas Poisoning Chlorine 4.0720016425
MESH:D005756 Gastritis Acetaminophen 13.7216983495
MESH:D005756 Gastritis Folic Acid 13.7217171786
MESH:D005756 Gastritis Zinc 13.7217241300
MESH:D005770 Gastrointestinal Neoplasms Curcumin 3.7918462866
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 9.7516452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 9.7516452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 9.858708960
MESH:D005885 Gingival Hyperplasia Phenytoin 9.859029455
MESH:D019214 Gingival Overgrowth Phenytoin 5.2916390469 14659971
MESH:D005901 Glaucoma Folic Acid 4.2116504073
MESH:D005909 Glioblastoma Carmustine 36.5116187019
MESH:D005909 Glioblastoma Curcumin 36.5117596214
MESH:D005909 Glioblastoma Dacarbazine 36.5112592361 12853885
MESH:D005909 Glioblastoma Doxorubicin 36.5117150277
MESH:D005909 Glioblastoma Ethylnitrosourea 36.5116436596
MESH:D005909 Glioblastoma Fenretinide 36.5116187019
MESH:D005909 Glioblastoma fotemustine 36.5112853885 12592361
MESH:D005909 Glioblastoma Genistein 36.5116598420
MESH:D005909 Glioblastoma temozolomide 36.5115865885
MESH:D005909 Glioblastoma trichostatin A 36.5118801729
MESH:D005910 Glioma marker/mechanism 16899598 16033832
MESH:D005910 Glioma Ethylnitrosourea 10.2418412241 16651633 16357521
MESH:D005910 Glioma Fluorouracil 10.2416145905
MESH:D005910 Glioma Methylnitrosourea 10.249825942
MESH:D005910 Glioma temozolomide 10.2410871815 16327979
MESH:D018316 Gliosarcoma Cyclophosphamide 4.5911389073
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.1316376943 15172196 11014644
MESH:D006130 Growth Disorders Zinc 3.2917217573
MESH:D006258 Head and Neck Neoplasms Cisplatin 16.9115464296 15102660
MESH:D006258 Head and Neck Neoplasms Curcumin 16.9118462866 18829502
MESH:D006258 Head and Neck Neoplasms decitabine 16.9119215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 16.9115692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 16.9115162350 18337622 15102660
MESH:D034381 Hearing Loss Cisplatin 3.4919898482
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.6315464296
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 7.9816080930
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 7.9820471113
MESH:D006330 Heart Defects, Congenital Folic Acid 7.9816524890 17286298
MESH:D006331 Heart Diseases Doxorubicin 5.7816879835 18674790 14766674 16330681 17875725 16707910 16244372 12587719 16495754 17888722 16244371 16144979 18006777
MESH:D006331 Heart Diseases Streptozocin 5.7812093613
MESH:D006333 Heart Failure Doxorubicin 8.1017481944
MESH:D006333 Heart Failure pirinixic acid 8.1020558911
MESH:D006333 Heart Failure Zinc 8.1017162251
MESH:D006335 Heart Injuries Zinc 4.8317074742
MESH:D016481 Helicobacter Infections Zinc 3.6717241300
MESH:D006390 Hemangioendothelioma 2-Acetylaminofluorene 9.986705139
MESH:D006390 Hemangioendothelioma Vinyl Chloride 9.9815380572
MESH:D006393 Hemangiopericytoma Vinyl Chloride 5.9210964802
MESH:D006394 Hemangiosarcoma 2-Acetylaminofluorene 14.966705139
MESH:D006394 Hemangiosarcoma chloroacetaldehyde 14.9610626228
MESH:D006394 Hemangiosarcoma Doxorubicin 14.9615692506
MESH:D006394 Hemangiosarcoma Vinyl Chloride 14.9612958735 12762079 11217710 12828392 15999577 12211074 15989139
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.5015720958
MESH:D006467 Hemophilia A Cyclophosphamide 4.3811918545
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 4.5914986274
MESH:D006505 Hepatitis Carbon Tetrachloride 2.7219900420 19110552
MESH:D006527 Hepatolenticular Degeneration Zinc 3.7917276780
MESH:D006529 Hepatomegaly Phenobarbital 5.5316109766
MESH:D006529 Hepatomegaly pirinixic acid 5.5316221962 19176532 18467677 19772884
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.1317701891
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 4.7716863852 16490937
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 4.777520565
MESH:D006558 Herpes Genitalis Estradiol 4.0915709030
MESH:D006561 Herpes Simplex resveratrol 3.2716876885
MESH:D015658 HIV Infections beta Carotene 3.4816960176
MESH:D006679 HIV Seropositivity Folic Acid 4.5717209195
MESH:D006689 Hodgkin Disease Cisplatin 26.5216170182 16200630
MESH:D006689 Hodgkin Disease Cyclophosphamide 26.5216135485 17606976
MESH:D006689 Hodgkin Disease Dacarbazine 26.5216170182 18501091
MESH:D006689 Hodgkin Disease Doxorubicin 26.5218501091 15147373 17606976
MESH:D006689 Hodgkin Disease Lomustine 26.5216135485
MESH:D006689 Hodgkin Disease Procarbazine 26.5217606976 16135485
MESH:D006689 Hodgkin Disease sodium arsenite 26.5212676792
MESH:D006689 Hodgkin Disease Vincristine 26.5216135485 17606976 15147373 16794504
MESH:D019584 Hot Flashes Estradiol 2.8217088409
MESH:D006930 Hyperalgesia Acetaminophen 1.9516870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.6116899240
MESH:D006937 Hypercholesterolemia Curcumin 6.6018704882
MESH:D006937 Hypercholesterolemia resveratrol 6.6017188708
MESH:D006943 Hyperglycemia methyl isocyanate 7.158440870
MESH:D006943 Hyperglycemia pirinixic acid 7.1520558911
MESH:D020138 Hyperhomocysteinemia Folic Acid 7.1516755160 16433478 16397167 16865747 16395265
MESH:D020138 Hyperhomocysteinemia Phenytoin 7.1510459572
MESH:D006949 Hyperlipidemias resveratrol 3.1816873680
MESH:D006965 Hyperplasia Diethylstilbestrol 3.5314722030 12960047
MESH:D006973 Hypertension Cyclosporine 3.7810903974
MESH:D006973 Hypertension Dexamethasone 3.7817042910
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.1815338365
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 3.7216612254
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.4817488730
MESH:D007021 Hypospadias Diethylstilbestrol 3.6816002989
MESH:D007154 Immune System Diseases Cyclophosphamide 4.3916076520
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 3.7417600658
MESH:D007246 Infertility Diethylstilbestrol 3.4715036965
MESH:D007248 Infertility, Male Cyclophosphamide 10.547193160 16517039
MESH:D007248 Infertility, Male decitabine 10.5417581917
MESH:D007248 Infertility, Male Methylnitrosourea 10.547193160
MESH:D007248 Infertility, Male sodium arsenite 10.5412646999 15346721
MESH:D007249 Inflammation Curcumin 15.3717151092 18403477 16956363
MESH:D007249 Inflammation Dexamethasone 15.378960868 11099482
MESH:D007249 Inflammation Diethylnitrosamine 15.3718785209
MESH:D007249 Inflammation resveratrol 15.3716366677
MESH:D007249 Inflammation Silymarin 15.3717213517
MESH:D007249 Inflammation Tamoxifen 15.3719457130
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 15.377812673 11698051 8273558 15177302 7562506
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.7418200517 18596194
MESH:D007251 Influenza, Human resveratrol 3.6116624496
MESH:D007333 Insulin Resistance bisphenol A 8.3916393666
MESH:D007333 Insulin Resistance Estradiol 8.3916393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 8.3916306350
MESH:D007414 Intestinal Neoplasms Curcumin 3.4010783313
MESH:D007511 Ischemia Zinc 3.7316584753
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.5015604871
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.2015464296
MESH:D007674 Kidney Diseases Acetaminophen 34.9215629191 12587719
MESH:D007674 Kidney Diseases Acrolein 34.9212488133
MESH:D007674 Kidney Diseases chloroacetaldehyde 34.9216221203
MESH:D007674 Kidney Diseases Cisplatin 34.9212649298 18289764 12231392 19839026 15190930
MESH:D007674 Kidney Diseases Cyclosporine 34.928314463 10903974 18776723
MESH:D007674 Kidney Diseases Doxorubicin 34.9215369732 15699352 16775033
MESH:D007674 Kidney Diseases Estradiol 34.9215618244
MESH:D007674 Kidney Diseases Ethylene Dibromide 34.9212628311
MESH:D007674 Kidney Diseases sodium arsenite 34.9220008137
MESH:D007674 Kidney Diseases Streptozocin 34.9212093613
MESH:D007674 Kidney Diseases Zinc 34.9216960431
MESH:D007676 Kidney Failure, Chronic Doxorubicin 7.3816707910
MESH:D007676 Kidney Failure, Chronic Zinc 7.3816518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 31.9916705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 31.9916705839
MESH:D007680 Kidney Neoplasms Cyclosporine 31.9912371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 31.9915003126 14681315 16762066
MESH:D007680 Kidney Neoplasms Estradiol 31.9915610895
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 31.9917379185
MESH:D007680 Kidney Neoplasms Fluorouracil 31.9916985049
MESH:D007680 Kidney Neoplasms Tamoxifen 31.9918625569
MESH:D007680 Kidney Neoplasms Vinyl Chloride 31.9912562636
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 3.8611231351
MESH:D007859 Learning Disorders Diethylstilbestrol 3.1717184923
MESH:D007889 Leiomyoma Curcumin 3.7118555241
MESH:D007938 Leukemia marker/mechanism 16412662
MESH:D007938 Leukemia Azacitidine 21.1019148494
MESH:D007938 Leukemia Curcumin 21.1018462866
MESH:D007938 Leukemia Cyclophosphamide 21.1010602166
MESH:D007938 Leukemia decitabine 21.1019235587 18980019
MESH:D007938 Leukemia Genistein 21.1017468513 18980019
MESH:D007938 Leukemia lomeguatrib 21.1017500047
MESH:D007938 Leukemia temozolomide 21.1017500047
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.2216085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.0118587576 18172266 17296974 17802794 17658394 17008537
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 3.3716106398
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 3.3610373061
MESH:D007951 Leukemia, Myeloid Azacitidine 11.4419077051
MESH:D007951 Leukemia, Myeloid decitabine 11.4419117987 17236224 18454857
MESH:D007951 Leukemia, Myeloid Hydroxyurea 11.4416532439
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 4.7317596541 18720364
MESH:D015470 Leukemia, Myeloid, Acute decitabine 4.7319010910 19387464 17679729 18206229 18460780 18704418
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 4.7318206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.5218055864
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 4.3219299654
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 2.9116087638
MESH:D007953 Leukemia, Radiation-Induced Radon 6.862021549
MESH:D015458 Leukemia, T-Cell Curcumin 3.8816106398
MESH:D007970 Leukopenia Cyclophosphamide 4.0410052129 11830472
MESH:D007972 Leukoplakia, Oral Fenretinide 5.1016707609
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 3.4915526292
MESH:D008064 Lipidoses Tamoxifen 2.4515342952 17567588
MESH:D008080 Liposarcoma Paclitaxel 3.9517353645
MESH:D008103 Liver Cirrhosis arsenite 18.1018296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 18.1017334410 11408273 11903743 16943688 21278145 16239168 17174718 17157831 16221502
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 18.1018522880 19638242 18665156 18407596 20032147
MESH:D008103 Liver Cirrhosis Phenobarbital 18.1021047994
MESH:D008103 Liver Cirrhosis Silymarin 18.1017213517
MESH:D008103 Liver Cirrhosis Vinyl Chloride 18.1015354062 11679801 12499459 12958735 15289165
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 22.6216248980 14724832 12632514 17922224 15925388 16116963 15730626 15057751 15370692 18705752 17557913 17976157 15818738 17944888 12666154 18317297 18277467 18395095 16136751 10355542 15876570 18205269 18006644 16033810 18418968 17721639 17869086 16097048 18472332 17565644 18412020 18279442 18251166 18263696 15338365 15052691 13678700 12609069 17698563 17900296 12445418 18481824 12389079 18166357 12898905 16638106 17525996 16027843 14716496 15123356 14620537 12586293 14512876 15362042 15673190 18339082 12649538 18187930 18472094 12741479 16015684 17766677 17714472 15996030 18210741 20821823 18054572 15959796 14748882 14716833 18395914 11481614 17761835 15650968 12445421 16011737 17640975 18429990 18376398 18420326 18156304 15893842 12546737 12632512 12667390 16192424 17481882 17631135 17708605 12958196 17823541 17805973 15931870
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 22.6218705752 17355460 18006644
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 22.6216718785
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 22.6216627068 15793283 15479170 15723089 16544323 15744066 15492853 16603200 15081153 15591649 15086199 17534399 17348192 14643895 15138612 15369754 17465448 16009107 18210741 16169303 16042886 17724770 17719030 12918455 18364076 15842777 15099470 17201889 15864749 15577212 16270385 17198567 15942678 15383259 12925901 16570917 18237412 18637143 18672772 18567088 17432682 15571005 14659978 15161499 15298665 15798949 15339415 15733078 17036385 14726149 15067225 18629640 17196135 15504291 17640959 17203207 18095165 18239293 15763062 14568256 17666798 14709902 15366600 17881167 18371158
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 22.6216595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 22.6217481882
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 22.6214716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Fenofibrate 22.6215474484
MESH:D008106 Liver Cirrhosis, Experimental Genistein 22.6217823541
MESH:D008106 Liver Cirrhosis, Experimental oltipraz 22.6216544323
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 22.6215474484
MESH:D008106 Liver Cirrhosis, Experimental silybin 22.6216169303
MESH:D008106 Liver Cirrhosis, Experimental Silymarin 22.6218277467 17198567 15754394 15864749
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 22.6218564211
MESH:D008107 Liver Diseases Acetaminophen 19.4319014921 12969438 16610002 19784758 11587558 16611625 12587719 19460945
MESH:D008107 Liver Diseases Carbon Tetrachloride 19.4316964402 16246199 15830285 15720792 17285989
MESH:D008107 Liver Diseases Curcumin 19.4316956363
MESH:D008107 Liver Diseases Diethylnitrosamine 19.4317034775
MESH:D008107 Liver Diseases Folic Acid 19.4316877991
MESH:D008107 Liver Diseases Phenobarbital 19.4319363144
MESH:D008107 Liver Diseases Phenytoin 19.4314986274
MESH:D008107 Liver Diseases Silymarin 19.4317213517
MESH:D008107 Liver Diseases Vinyl Chloride 19.4316270392 15211785
MESH:D008108 Liver Diseases, Alcoholic Silymarin 5.0217213517
MESH:D017093 Liver Failure Carbon Tetrachloride 3.2615123358
MESH:D017114 Liver Failure, Acute Acetaminophen 11.5116871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 11.5116899240 14706259
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 11.5117457977
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 77.937678174
MESH:D008113 Liver Neoplasms 2-Acetylaminofluorene 77.9316273603 11376686 18001218 14678523 10672840 10737359
MESH:D008113 Liver Neoplasms 2-nitrofluorene 77.9315890375
MESH:D008113 Liver Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 77.9315890375
MESH:D008113 Liver Neoplasms 9,10-Dimethyl-1,2-benzanthracene 77.939643874
MESH:D008113 Liver Neoplasms Aflatoxin B1 77.932125692 9163691 18177683 15890375
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 77.9320195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 77.9319294768
MESH:D008113 Liver Neoplasms Clofibric Acid 77.9317602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 77.9318977376 10737359 20452335 20492335 19551842 21278145 2422723 2862719 18978307 20405173 19090486 15885732 19638242 19427195 20501860 19499222 19254457 19073162 19690152 21071580 12112319 21047994 20118626 21167192 19294768 19255062 12771043 19996281 20137499 19833225 18644402 16942905 15175105 19642983 18648771 20434301 19812893 9163691 20101389 19256749 18754104 20583210 19850985 19426721
MESH:D008113 Liver Neoplasms Diethylstilbestrol 77.9315890375 16712894
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 77.933113478 15890375
MESH:D008113 Liver Neoplasms Fenofibrate 77.9318978307
MESH:D008113 Liver Neoplasms Fluorouracil 77.9316603448 18383874 15113037 17045692
MESH:D008113 Liver Neoplasms Methapyrilene 77.9315890375
MESH:D008113 Liver Neoplasms Mitomycin 77.9315113037
MESH:D008113 Liver Neoplasms Phenobarbital 77.938742319 19482888 19812893 15975961 19073162 21047994
MESH:D008113 Liver Neoplasms Piperonyl Butoxide 77.9319690152 15890375 20101389 18648771
MESH:D008113 Liver Neoplasms pirinixic acid 77.9315890375 20007298 16377806
MESH:D008113 Liver Neoplasms resveratrol 77.9319812893 19321006 19073162 20405173
MESH:D008113 Liver Neoplasms Silymarin 77.9319168119
MESH:D008113 Liver Neoplasms sodium arsenite 77.9315276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 77.9316684651
MESH:D008113 Liver Neoplasms Vinyl Chloride 77.9311679801 10629081 15999577 10964802 11024202 12762079 12211074
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 49.842876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental 2-Acetylaminofluorene 49.846150874 534488 1399818
MESH:D008114 Liver Neoplasms, Experimental 9,10-Dimethyl-1,2-benzanthracene 49.841399818
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 49.848603461
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 49.8418544905
MESH:D008114 Liver Neoplasms, Experimental beta Carotene 49.8417113696
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 49.8415583823 12014681
MESH:D008114 Liver Neoplasms, Experimental chloroacetaldehyde 49.8410626228
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 49.8418093689 18775883 9362446 18079962 17942915 2563599 16842330 19009564 3124819 16267830 19126423 17174075 18164116 18544905 18253720 19539802 18308698 19004024 18282651 19519916 17854601 21159647
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 49.841848544 15603536 6150874
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 49.8416842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Fenofibrate 49.8418253720 18775883
MESH:D008114 Liver Neoplasms, Experimental kojic acid 49.8418544905
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 49.841399818 2563599 17172636 18308698 6150874
MESH:D008114 Liver Neoplasms, Experimental Vinyl Chloride 49.8412562636
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 4.5616080182
MESH:D008171 Lung Diseases Acetylcysteine 19.9312815614
MESH:D008171 Lung Diseases Acrolein 19.9311504702
MESH:D008171 Lung Diseases Ascorbic Acid 19.9316863852
MESH:D008171 Lung Diseases methyl isocyanate 19.931396463
MESH:D008171 Lung Diseases Ozone 19.938266340 19066396
MESH:D008171 Lung Diseases sodium arsenite 19.9319095001
MESH:D055370 Lung Injury Ozone 2.9720417186
MESH:D008175 Lung Neoplasms 2-Acetylaminofluorene 55.9411376686
MESH:D008175 Lung Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 55.9415893417 16401635 19931552 18813816 14755239 16061637 18508827 17139156 12438228 9255578 15172992
MESH:D008175 Lung Neoplasms 9,10-Dimethyl-1,2-benzanthracene 55.9411376689
MESH:D008175 Lung Neoplasms Aflatoxin B1 55.9414755239
MESH:D008175 Lung Neoplasms arsenite 55.9416809336
MESH:D008175 Lung Neoplasms Ascorbic Acid 55.9416401635
MESH:D008175 Lung Neoplasms Azacitidine 55.9421224363
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 55.9420464547 17053015 18569708 18816296 20869020 6695378 20064080 20135361 18520028
MESH:D008175 Lung Neoplasms beta Carotene 55.9416401635
MESH:D008175 Lung Neoplasms Cisplatin 55.9411798837 17225452 6189445
MESH:D008175 Lung Neoplasms Curcumin 55.9416243823 19359593 18462866
MESH:D008175 Lung Neoplasms Dexamethasone 55.9415824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 55.9421163286 20970405 6695378 20512841
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 55.9416061637 11884234 19555203
MESH:D008175 Lung Neoplasms Doxorubicin 55.9417418594 6189445
MESH:D008175 Lung Neoplasms Ethylnitrosourea 55.9417703301 16271038 6695378 16019985
MESH:D008175 Lung Neoplasms Fluorouracil 55.9415246190
MESH:D008175 Lung Neoplasms Methylnitrosourea 55.9418062963
MESH:D008175 Lung Neoplasms Ozone 55.948597069 7614698
MESH:D008175 Lung Neoplasms Radon 55.943440675
MESH:D008175 Lung Neoplasms silybin 55.9416788158
MESH:D008175 Lung Neoplasms sodium arsenite 55.9416712894 17077188 17306315 15276417 19931552
MESH:D008175 Lung Neoplasms Tamoxifen 55.9418625569
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 55.9411807781
MESH:D008175 Lung Neoplasms Vincristine 55.9419825857 6189445
MESH:D008175 Lung Neoplasms Vinyl Chloride 55.9412958735 12562636
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 3.8715086387
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 2.9917718048
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.2215166399
MESH:D008223 Lymphoma 9,10-Dimethyl-1,2-benzanthracene 28.7711376689
MESH:D008223 Lymphoma Curcumin 28.7718462866
MESH:D008223 Lymphoma Cyclophosphamide 28.7712854902
MESH:D008223 Lymphoma decitabine 28.7719470736
MESH:D008223 Lymphoma Diethylstilbestrol 28.7715700306
MESH:D008223 Lymphoma Doxorubicin 28.7716098063
MESH:D008223 Lymphoma Ethylnitrosourea 28.7715790496
MESH:D008223 Lymphoma Methylnitrosourea 28.7711418001 16257854
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 12.3316675587
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 12.3314633661
MESH:D016393 Lymphoma, B-Cell resveratrol 12.3317088997
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 14.3111911406
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 14.3117654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 14.3114749477
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 14.3114749477
MESH:D016399 Lymphoma, T-Cell Curcumin 14.2816173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 14.2815621674
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 14.2815375218
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.5716002989
MESH:D015674 Mammary Neoplasms, Animal resveratrol 11.6815688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 11.6819428831
MESH:D015674 Mammary Neoplasms, Animal Vinyl Chloride 11.6812562636
MESH:D008325 Mammary Neoplasms, Experimental 2,4-diaminotoluene 45.6411921183
MESH:D008325 Mammary Neoplasms, Experimental 9,10-Dimethyl-1,2-benzanthracene 45.6418840765 12844480 1500032 16153821 10697514 8985016 11807958 16082771
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 45.6415458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 45.6417203775 11807958 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental Ethylene Dibromide 45.6411921183
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 45.6418041768 10838139 10767621
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 45.6410697514
MESH:D008325 Mammary Neoplasms, Experimental Genistein 45.6412929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 45.6415688392 10767621 16051031 11807958 17131329 16944150 17020996 15313902 12931682 16619500 14633655 15113128 16827153 11751437 19196723 14999141 10838139
MESH:D008325 Mammary Neoplasms, Experimental Procarbazine 45.6411921183
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 45.648985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 45.6416827153 19196722 19196723 11731420 14580682
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 45.648985016
MESH:D008325 Mammary Neoplasms, Experimental Zinc 45.6412773700
MESH:D020149 Manganese Poisoning Estradiol 9.5319453300
MESH:D020149 Manganese Poisoning Tamoxifen 9.5319453300
MESH:D019767 Maxillofacial Abnormalities Folic Acid 4.7716832597
MESH:D008545 Melanoma Carboplatin 42.8316225601 16342250 11712820 12040289
MESH:D008545 Melanoma Carmustine 42.8312393984
MESH:D008545 Melanoma Cisplatin 42.8316248763 11135225 17761969 18176117 18505091 12883367 15577323 12393984 17023156 12374674 16809738 18332650 16432458
MESH:D008545 Melanoma Curcumin 42.8318462866 17885582
MESH:D008545 Melanoma Dacarbazine 42.8310623706 17508024 12417787 16098027 17973783 18332650 15917704 11712820 16809738 15577320 15577323 16273263 15522559 12535206 11254118 16508601 15176220 18445842 18089842 16928243 16939954 17709802 12025231 17562445 16248763 17239242 18505091 17761969 17623835 11135225 17023156 18281670 17576460 16966688 12556972 12883367 17119449 12202904 15020614 12640292 16034308 11746506 17334785 12393984 18176117 16760174 12439608 16225601
MESH:D008545 Melanoma decitabine 42.8317785578 16505122
MESH:D008545 Melanoma Dinitrochlorobenzene 42.8317334785 12202904
MESH:D008545 Melanoma Doxorubicin 42.8316827129
MESH:D008545 Melanoma epigallocatechin gallate 42.8317992120 11746506
MESH:D008545 Melanoma Fenretinide 42.8316270382
MESH:D008545 Melanoma fotemustine 42.8315020614 17239242 15522559 16273263 11135225 16225601
MESH:D008545 Melanoma Lomustine 42.8315577320
MESH:D008545 Melanoma Paclitaxel 42.8312040289 12025231 16342250
MESH:D008545 Melanoma resveratrol 42.8317992120
MESH:D008545 Melanoma sodium arsenite 42.8319082730 16487513
MESH:D008545 Melanoma Tamoxifen 42.8312393984 19393235
MESH:D008545 Melanoma temozolomide 42.8310623706 17623835 17576461 16432458 18281670 12829675 12374674 16260697 16225601 16248763 16260693 15577323
MESH:D008545 Melanoma trichostatin A 42.8316505122
MESH:D018328 Melanoma, Amelanotic Cisplatin 27.4515990972
MESH:D018328 Melanoma, Amelanotic Dacarbazine 27.4515990972
MESH:D018328 Melanoma, Amelanotic Nimustine 27.4515990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 27.4515990972
MESH:D018328 Melanoma, Amelanotic Vincristine 27.4515990972
MESH:D008546 Melanoma, Experimental 2-oxothiazolidine-4-carboxylic acid 19.1110803710
MESH:D008546 Melanoma, Experimental Acetaminophen 19.1119513568
MESH:D008546 Melanoma, Experimental Acrolein 19.1110803710
MESH:D008546 Melanoma, Experimental Cyclophosphamide 19.1116388313
MESH:D008569 Memory Disorders Curcumin 3.2817263510
MESH:D008579 Meningioma Ethylnitrosourea 5.0417943659
MESH:D008607 Mental Retardation Phenytoin 3.269212184
MESH:D008654 Mesothelioma Cisplatin 4.8317638057
MESH:D008654 Mesothelioma Doxorubicin 4.8317638057
MESH:D008659 Metabolic Diseases resveratrol 3.5317112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 3.8416801185
MESH:D008679 Metaplasia Ozone 4.1610496685
MESH:D053842 Microsatellite Instability Methylnitronitrosoguanidine 4.9617671175
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.6515792986
MESH:D009006 Monosomy Azacitidine 5.1419299654
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 10.1116381670
MESH:D009062 Mouth Neoplasms Fenretinide 10.1116274795
MESH:D009062 Mouth Neoplasms Fluorouracil 10.1118986760 16757204
MESH:D052016 Mucositis Doxorubicin 9.3617415656
MESH:D052016 Mucositis irinotecan 9.3617159606
MESH:D009101 Multiple Myeloma Azacitidine 23.1819549372 18443271
MESH:D009101 Multiple Myeloma Curcumin 23.1819372569
MESH:D009101 Multiple Myeloma decitabine 23.1818172295
MESH:D009101 Multiple Myeloma Dexamethasone 23.1815867202 16118317 15744524
MESH:D009101 Multiple Myeloma Paclitaxel 23.1814749477
MESH:D009101 Multiple Myeloma resveratrol 23.1817164350 17049120 16490592 17935668 16267019 14749477
MESH:D009101 Multiple Myeloma trichostatin A 23.1818172295
MESH:D009134 Muscular Atrophy, Spinal Curcumin 15.8417962980
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 15.8417962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 15.8417962980
MESH:D009135 Muscular Diseases Bezafibrate 7.7416239165
MESH:D009135 Muscular Diseases pirinixic acid 7.7416239165
MESH:D009145 Mushroom Poisoning Silymarin 6.0017213517
MESH:D009190 Myelodysplastic Syndromes Azacitidine 8.9017611569 19805378 18720364 17596541
MESH:D009190 Myelodysplastic Syndromes decitabine 8.9016882708 18608210 19157545 19010910
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 8.909809623
MESH:D009203 Myocardial Infarction Doxorubicin 12.5619429709 15857846
MESH:D009203 Myocardial Infarction Genistein 12.5617141266
MESH:D009203 Myocardial Infarction pirinixic acid 12.5619151258
MESH:D009203 Myocardial Infarction resveratrol 12.5616525036 16456233 17188708 17125593 16317513 17015251
MESH:D009203 Myocardial Infarction Vincristine 12.5617284715
MESH:D017202 Myocardial Ischemia resveratrol 3.2417125593 17015251
MESH:D015428 Myocardial Reperfusion Injury Estradiol 9.8216810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 9.8217141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 9.8216411023
MESH:D009205 Myocarditis resveratrol 3.8417322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 9.4317484760
MESH:D020191 Myoclonic Epilepsies, Progressive Phenytoin 9.4317484760
MESH:D009224 Myotonia Congenita Phenytoin 4.491896199
MESH:D009336 Necrosis 2,4-dinitrotoluene 12.6018551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 12.6018551238 7678174
MESH:D009336 Necrosis 2-nitropropane 12.6012195237
MESH:D009361 Neoplasm Invasiveness Curcumin 3.4918495463
MESH:D009362 Neoplasm Metastasis Acetylcysteine 16.1114720322
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 16.119029167 3581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 16.1118259882
MESH:D009362 Neoplasm Metastasis irinotecan 16.1118259882
MESH:D009362 Neoplasm Metastasis Paclitaxel 16.1115867366
MESH:D009362 Neoplasm Metastasis Tamoxifen 16.1119393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.1219410462
MESH:D009369 Neoplasms 9,10-Dimethyl-1,2-benzanthracene 43.2411544531
MESH:D009369 Neoplasms Acrolein 43.2417329238
MESH:D009369 Neoplasms Benzo(a)pyrene 43.2411141357
MESH:D009369 Neoplasms beta Carotene 43.2417051425
MESH:D009369 Neoplasms Carboplatin 43.2417925555 18854779
MESH:D009369 Neoplasms Cisplatin 43.2416773208
MESH:D009369 Neoplasms Cyclophosphamide 43.2418854779
MESH:D009369 Neoplasms decitabine 43.2419470736 19116145 17925555
MESH:D009369 Neoplasms Diethylstilbestrol 43.2415313581
MESH:D009369 Neoplasms Fenretinide 43.2415958647 17353921
MESH:D009369 Neoplasms Fluorouracil 43.2416928823 18600527 18239605
MESH:D009369 Neoplasms Methylnitrosourea 43.2415533788
MESH:D009369 Neoplasms pirinixic acid 43.2417405874
MESH:D009369 Neoplasms sodium arsenite 43.2411559025
MESH:D009369 Neoplasms Vinyl Chloride 43.2411911487
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 14.5116707424
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 14.5112696579
MESH:D009374 Neoplasms, Experimental resveratrol 14.518985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 14.5120056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 7.7412497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 7.7419189210 19196722 19200415
MESH:D009381 Neoplasms, Radiation-Induced Radon 6.862021549
MESH:D009389 Neovascularization, Pathologic arsenite 7.1115738583
MESH:D009389 Neovascularization, Pathologic Estradiol 7.1117289903
MESH:D009393 Nephritis Acrolein 5.3412653641
MESH:D009395 Nephritis, Interstitial Cisplatin 3.5615464296
MESH:D009401 Nephrosis Doxorubicin 3.8616636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.5017954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 6.6218481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 6.6216889571 15640375
MESH:D009421 Nervous System Malformations bisphenol A 16.3216427766 11399458
MESH:D009421 Nervous System Malformations Diethylstilbestrol 16.3211399458
MESH:D009421 Nervous System Malformations Estradiol 16.3211399458 16427766
MESH:D009421 Nervous System Malformations Genistein 16.3216427766
MESH:D009423 Nervous System Neoplasms Curcumin 4.6918462866
MESH:D009436 Neural Tube Defects Acetylcysteine 11.9319446573
MESH:D009436 Neural Tube Defects Folic Acid 11.9317438019
MESH:D009436 Neural Tube Defects Phenytoin 11.939118846
MESH:D009436 Neural Tube Defects sodium arsenite 11.9312854658
MESH:D009442 Neurilemmoma Ethylnitrosourea 10.2216003739 16651423 17160924
MESH:D009442 Neurilemmoma Methylnitrosourea 10.2211555667
MESH:D009447 Neuroblastoma Cisplatin 15.228761367
MESH:D009447 Neuroblastoma Cyclophosphamide 15.2216115947 15176712 8761367
MESH:D009447 Neuroblastoma Doxorubicin 15.2215555623
MESH:D009447 Neuroblastoma irinotecan 15.228761367
MESH:D009447 Neuroblastoma temozolomide 15.2215176712
MESH:D019636 Neurodegenerative Diseases Acetaminophen 13.7318514411
MESH:D019636 Neurodegenerative Diseases Acrolein 13.7311342003
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 13.7320387270
MESH:D019636 Neurodegenerative Diseases resveratrol 13.7317652729
MESH:D017599 Neuroectodermal Tumors Carboplatin 26.1812837982
MESH:D017599 Neuroectodermal Tumors Cisplatin 26.188761367
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 26.188761367 12837982
MESH:D017599 Neuroectodermal Tumors irinotecan 26.188761367
MESH:D017599 Neuroectodermal Tumors Vincristine 26.1812837982
MESH:D020078 Neurogenic Inflammation resveratrol 3.5417929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.1720387270
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 4.7516303764
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 2.7516436463
MESH:D009503 Neutropenia Cyclophosphamide 6.888291058
MESH:D009503 Neutropenia Folic Acid 6.8816322990
MESH:D009669 Nose Neoplasms Ethylene Dibromide 7.649385384
MESH:D009669 Nose Neoplasms Procarbazine 7.649385384
MESH:D009765 Obesity Ascorbic Acid 5.4817217161
MESH:D009765 Obesity Curcumin 5.4819297423
MESH:D009765 Obesity pirinixic acid 5.4820558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 10.5716049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 10.5716049721
MESH:D009784 Occupational Diseases Vinyl Chloride 10.5712061072
MESH:D009837 Oligodendroglioma Ethylnitrosourea 5.0417160924
MESH:D009845 Oligospermia Cyclophosphamide 3.7916517039
MESH:D010014 Osteolysis Paclitaxel 4.0615867366
MESH:D010018 Osteomalacia Phenobarbital 9.0117016548
MESH:D010018 Osteomalacia Phenytoin 9.0117016548
MESH:D010024 Osteoporosis Curcumin 5.2018719352
MESH:D010024 Osteoporosis Genistein 5.2019401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 7.2916169203
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 7.2917513867
MESH:D012516 Osteosarcoma Doxorubicin 3.3415930896
MESH:D010049 Ovarian Diseases bisphenol A 4.0611985600
MESH:D010051 Ovarian Neoplasms 9,10-Dimethyl-1,2-benzanthracene 26.6016891317
MESH:D010051 Ovarian Neoplasms Cisplatin 26.6017225452 15464296 6897625 19769630
MESH:D010051 Ovarian Neoplasms Curcumin 26.6018462866 19020741
MESH:D010051 Ovarian Neoplasms decitabine 26.6019331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 26.6019401270
MESH:D010051 Ovarian Neoplasms Fenretinide 26.6016133793
MESH:D010051 Ovarian Neoplasms Genistein 26.6019005980
MESH:D010051 Ovarian Neoplasms Paclitaxel 26.6011161223
MESH:D010051 Ovarian Neoplasms sodium arsenite 26.6015276417 17306315
MESH:D010051 Ovarian Neoplasms trichostatin A 26.6019331143
MESH:D010146 Pain Acetaminophen 7.0016870215
MESH:D010146 Pain Cyclophosphamide 7.0012161096 18093676
MESH:D010146 Pain Phenytoin 7.0015215642
MESH:D010190 Pancreatic Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 48.8312384795
MESH:D010190 Pancreatic Neoplasms Cisplatin 48.8319003803
MESH:D010190 Pancreatic Neoplasms Curcumin 48.8319196508 19401701 17440100
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 48.8311332152
MESH:D010190 Pancreatic Neoplasms Dacarbazine 48.8311583197
MESH:D010190 Pancreatic Neoplasms decitabine 48.8319294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 48.8316540662
MESH:D010190 Pancreatic Neoplasms Fenretinide 48.8315580305
MESH:D010190 Pancreatic Neoplasms Fluorouracil 48.8315113037 16929163 19003803 16500647
MESH:D010190 Pancreatic Neoplasms gemcitabine 48.8311504793 16929163 17440100 18383843 18992248
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 48.8316965848
MESH:D010190 Pancreatic Neoplasms Mitomycin 48.8315113037
MESH:D010190 Pancreatic Neoplasms Phenobarbital 48.8316965848
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 48.8315976015
MESH:D010190 Pancreatic Neoplasms trichostatin A 48.8319294695
MESH:D010212 Papilloma 9,10-Dimethyl-1,2-benzanthracene 7.0917234724 15173996 16517061
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 7.0912065085 18922899 8330346 18404319
MESH:D010300 Parkinson Disease Acrolein 3.1717690948
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.4315464296
MESH:D010538 Peritonitis Ozone 3.2416369182
MESH:D010787 Photosensitivity Disorders Acrolein 4.8011550810
MESH:D003557 Phyllodes Tumor Dacarbazine 11.2417983394
MESH:D003557 Phyllodes Tumor Doxorubicin 11.2417983394
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.2314722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 3.7715687265 16977796
MESH:D010997 Pleural Neoplasms Cisplatin 10.8217638057
MESH:D010997 Pleural Neoplasms Doxorubicin 10.8217638057
MESH:D011014 Pneumonia Ozone 3.4818381685 18929643 18007984
MESH:D017689 Polydactyly Phenytoin 4.239212184
MESH:D017285 Polymyositis Vinyl Chloride 5.9211642524
MESH:D011230 Precancerous Conditions Cyclosporine 10.6312371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 10.632563599
MESH:D011230 Precancerous Conditions Phenobarbital 10.632563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 9.1121297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 9.1121297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Vincristine 9.1121297632
MESH:D011225 Pre-Eclampsia Zinc 3.4217114810
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 11.1310548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 11.1317184923
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 11.1316679765
MESH:D055728 Primary Myelofibrosis decitabine 9.4217616702
MESH:D055728 Primary Myelofibrosis trichostatin A 9.4217616702
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 7.7420887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 7.7420887781
MESH:D011471 Prostatic Neoplasms Azacitidine 8.9418324645
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 8.9417292933
MESH:D011471 Prostatic Neoplasms bisphenol A 8.9416740699
MESH:D011471 Prostatic Neoplasms Curcumin 8.9411398177 18769126 12497104 18226269 10851300 18156803 15129424
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 8.9417136230
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 8.9417136230 15846301 15046698
MESH:D011471 Prostatic Neoplasms Doxorubicin 8.9415749863 15897917 16868541 18437689 16729912 16888761
MESH:D011471 Prostatic Neoplasms Estradiol 8.9416740699
MESH:D011471 Prostatic Neoplasms Fenretinide 8.9417024972
MESH:D011471 Prostatic Neoplasms Fluorouracil 8.9419082440 18626508
MESH:D011471 Prostatic Neoplasms Genistein 8.9416925846 15256057 15378649
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 8.9412376480 15682402
MESH:D011471 Prostatic Neoplasms Paclitaxel 8.9417172428 16356831 16729912 17136230
MESH:D011471 Prostatic Neoplasms resveratrol 8.9416731767 17675339 15767336 17636462 17718901 17804756
MESH:D011471 Prostatic Neoplasms sodium arsenite 8.9416039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 8.9415067354
MESH:D011471 Prostatic Neoplasms trichostatin A 8.9419789329 18798265
MESH:D011471 Prostatic Neoplasms Zinc 8.9416517595 16700911 12429649 16606632
MESH:D019310 Pseudolymphoma Phenobarbital 9.4412752131
MESH:D019310 Pseudolymphoma Phenytoin 9.4412752131 8603615 1419762
MESH:D011565 Psoriasis Cyclosporine 1.8116882103
MESH:D011629 Puberty, Precocious bisphenol A 3.8610548101
MESH:D011656 Pulmonary Emphysema Curcumin 3.7019168576
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 4.3914606601
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 5.0816636934
MESH:D011658 Pulmonary Fibrosis methyl isocyanate 5.087708994
MESH:D011928 Raynaud Disease Vinyl Chloride 5.2216977343
MESH:D012004 Rectal Neoplasms Fluorouracil 3.2018286688 16160472 15538739 18722050
MESH:D051437 Renal Insufficiency Acrolein 17.1412732208
MESH:D051437 Renal Insufficiency Cisplatin 17.1415464296
MESH:D051437 Renal Insufficiency Doxorubicin 17.1417922066
MESH:D051437 Renal Insufficiency Folic Acid 17.1415728788
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.6416325855
MESH:D015427 Reperfusion Injury pirinixic acid 4.7019058328
MESH:D015427 Reperfusion Injury resveratrol 4.7017058453 16314181 16317513 17520802 15827377
MESH:D012120 Respiration Disorders Chlorine 4.2718579056
MESH:D012128 Respiratory Distress Syndrome, Adult Acetylcysteine 10.3912210543
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 10.3918379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 10.3918379247 11700416
MESH:D012162 Retinal Degeneration Fenretinide 10.9116303925
MESH:D012162 Retinal Degeneration Methylnitrosourea 10.9118155124 18172121
MESH:D012162 Retinal Degeneration Zinc 10.9116584753
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 2.9616849425
MESH:D012175 Retinoblastoma Methylnitrosourea 4.5611555667
MESH:D012208 Rhabdomyosarcoma decitabine 3.5419155313
MESH:D012509 Sarcoma Curcumin 15.8218462866
MESH:D012509 Sarcoma Dacarbazine 15.8217898927 18313854
MESH:D012509 Sarcoma Doxorubicin 15.8216767912 17203757 17710206 15675481 15625365 18313854
MESH:D012509 Sarcoma Vinyl Chloride 15.8212828392
MESH:D012512 Sarcoma, Ewing's Cisplatin 7.5214601052
MESH:D012512 Sarcoma, Ewing's Doxorubicin 7.5214601052 16326096
MESH:D012513 Sarcoma, Experimental Lomustine 6.427150475
MESH:D012514 Sarcoma, Kaposi Doxorubicin 3.8717846226
MESH:D012559 Schizophrenia Folic Acid 2.7416641680
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 8.8616636934
MESH:D012595 Scleroderma, Systemic Vinyl Chloride 8.8614979077
MESH:D012640 Seizures 2,4-dinitrotoluene 8.5018551238
MESH:D012640 Seizures 2,6-dinitrotoluene 8.5018551238
MESH:D012640 Seizures Phenobarbital 8.503137016 4039156 16876388 11442880
MESH:D012640 Seizures Phenytoin 8.503691417 15946322 16876388 10029267 9844417 11044598 19919933 3137016
MESH:D003294 Seizures, Febrile Phenobarbital 3.906407741
MESH:D018805 Sepsis Curcumin 3.2918389075
MESH:D012871 Skin Diseases Ascorbic Acid 4.3118709164
MESH:D012871 Skin Diseases Folic Acid 4.3118709164
MESH:D012878 Skin Neoplasms 9,10-Dimethyl-1,2-benzanthracene 18.8611376689 8985016 15173996 16517061
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 18.8610029692 19755658
MESH:D012878 Skin Neoplasms Doxorubicin 18.8615692506
MESH:D012878 Skin Neoplasms Fenretinide 18.8616467112
MESH:D012878 Skin Neoplasms resveratrol 18.868985016 15837718
MESH:D012878 Skin Neoplasms sodium arsenite 18.8619524636 18572023
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 18.868330346 11807781 18404319 12065085 8985016
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.4015464296
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.6617203757 15625365 16767912
MESH:D013088 Spermatocele Diethylstilbestrol 8.7316709447 16002989
MESH:D013088 Spermatocele Tamoxifen 8.7316709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 4.5916517039
MESH:D013118 Spinal Cord Diseases Folic Acid 4.5716361298
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.1219457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.0412854658
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.3312587719
MESH:D013262 Stevens-Johnson Syndrome Phenytoin 4.2520235791
MESH:D013272 Stomach Diseases beta Carotene 7.5717638125
MESH:D013272 Stomach Diseases Dexamethasone 7.5715472012
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 20.042093021 20155912
MESH:D013274 Stomach Neoplasms Cisplatin 20.0417522103 18396642 15958060
MESH:D013274 Stomach Neoplasms decitabine 20.0419037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 20.0418456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 20.0416033868
MESH:D013274 Stomach Neoplasms Ethylene Dibromide 20.043768853
MESH:D013274 Stomach Neoplasms Fluorouracil 20.0417522103 17498489 18567086 16424979 18396642 16951190 17172411 15786421 19084572 19015929
MESH:D013274 Stomach Neoplasms Folic Acid 20.0417171786
MESH:D013274 Stomach Neoplasms irinotecan 20.0415723263
MESH:D013274 Stomach Neoplasms Methylnitrosourea 20.0416257854 18593901 15930296
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 20.0412958204 17575124
MESH:D013274 Stomach Neoplasms Paclitaxel 20.0418396642 18506536
MESH:D013274 Stomach Neoplasms Vinyl Chloride 20.0412562636
MESH:D013276 Stomach Ulcer Acetylcysteine 13.8717918041
MESH:D013276 Stomach Ulcer Ascorbic Acid 13.8718726076
MESH:D013276 Stomach Ulcer beta Carotene 13.8712500499
MESH:D013276 Stomach Ulcer Curcumin 13.8719188055 16631530
MESH:D013276 Stomach Ulcer Dexamethasone 13.8715138204
MESH:D020521 Stroke Acrolein 10.2816269634
MESH:D020521 Stroke Ascorbic Acid 10.2816517955 16403987
MESH:D020521 Stroke Folic Acid 10.2816517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.6516321402
MESH:D019966 Substance-Related Disorders bisphenol A 3.0716684133 16045194
MESH:D015173 Supratentorial Neoplasms Carboplatin 15.2312837982
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 15.2312837982
MESH:D015173 Supratentorial Neoplasms Vincristine 15.2312837982
MESH:D024801 Tauopathies Paclitaxel 3.8916930453
MESH:D013736 Testicular Neoplasms Cisplatin 3.7717225452 15464296
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 9.2415790496
MESH:D013953 Thymus Neoplasms Methylnitrosourea 9.2411418001
MESH:D013964 Thyroid Neoplasms Butyrates 22.4817967635
MESH:D013964 Thyroid Neoplasms Dacarbazine 22.4811815960 15634649
MESH:D013964 Thyroid Neoplasms decitabine 22.4817967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 22.487505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 22.4816010429 17909728
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 22.483078959 7505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 22.481399818
MESH:D013978 Tibial Fractures Estradiol 3.7419048282
MESH:D014062 Tongue Neoplasms Fluorouracil 11.9116280240
MESH:D014062 Tongue Neoplasms resveratrol 11.9116227395
MESH:D014062 Tongue Neoplasms Zinc 11.9116543248
MESH:D014511 Uremia methyl isocyanate 6.008440870
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 38.1916049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 38.1916049721
MESH:D001749 Urinary Bladder Neoplasms 2-Acetylaminofluorene 38.191399818 15867355 15289314
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 38.1917053015
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 38.1915464296 17225452 12973940
MESH:D001749 Urinary Bladder Neoplasms Curcumin 38.1918593936
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 38.1914692829
MESH:D001749 Urinary Bladder Neoplasms decitabine 38.1919087683 17616700
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 38.1916712894 17306315 16452187
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 38.1917653716
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 38.1916720286
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 38.1917306315 11723127 16712894 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 38.198653321 17572228 16712894
MESH:D014565 Urogenital Neoplasms Curcumin 4.3418462866
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 8.9310091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 8.9310091137
MESH:D014581 Urticaria Acetaminophen 2.1310982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 26.3616803524
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 26.3616175088
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 26.3616154183
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 26.3616803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 26.3617473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 26.3611813266
MESH:D014591 Uterine Diseases bisphenol A 10.7014652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 10.7014652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 6.8715809267 16690809
MESH:D014594 Uterine Neoplasms resveratrol 6.8717044934
MESH:D014604 Uveal Neoplasms decitabine 3.9717785578
MESH:D014605 Uveitis Cyclosporine 8.661336536
MESH:D014605 Uveitis Dexamethasone 8.661336536
MESH:D014625 Vaginal Neoplasms Cisplatin 19.1215577323
MESH:D014625 Vaginal Neoplasms Dacarbazine 19.1215577323
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 19.1216513791 16002989
MESH:D014625 Vaginal Neoplasms temozolomide 19.1215577323
MESH:D014652 Vascular Diseases sodium arsenite 3.5017056641
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 7.3517678736 17638931 16364871 17334414
MESH:D018487 Ventricular Dysfunction, Left resveratrol 7.3517488730
MESH:D014839 Vomiting Cisplatin 3.7811897121
MESH:D014985 Xerophthalmia Cyclosporine 3.5017120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA239
  • No data
    Releated disease ID Related disease Name
    PA443622Carcinoma, Non-Small-Cell Lung
    PA446171Leukemia, Myelogenous, Chronic, BCR-ABL Positive
    PA444818Lung Neoplasms
    PA445062Neoplasms
    PA443560Breast Neoplasms
    PA444283Glioblastoma
    PA446108Colorectal Neoplasms
    PA444284Glioma
    Releated drug ID Related drug Name
    PA449014cisplatin
    PA449748gemcitabine
    PA448601beta carotene
    PA137867605O6-(4-Bromothenyl)guanine
    PA451609temozolomide
    PA450947phenytoin
    PA448810carmustine
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018