AutismKB 2.0

Annotation Detail for MGP


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Basic Information Top
Gene Symbol:MGP ( MGLAP,NTI )
Gene Full Name: matrix Gla protein
Band: 12p12.3
Quick LinksEntrez ID:4256; OMIM: 154870; Uniprot ID:MGP_HUMAN; ENSEMBL ID: ENSG00000111341; HGNC ID: 7060
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
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Pathway IDPathway Name
200044Validated transcriptional targets of AP1 family members Fra1 and Fra2
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1918Atherosclerosis
1995Varicosity
2196Periodontal disease
2236Cardiovascular disease
Desease Name
tooth loss
lead toxicity
RENAL
kidney stone disease
METABOLIC
No data
Desease Name
Keutel syndrome
Natural teeth remaining intact
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of MGP mRNAaffects expression 20406850
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of MGP mRNAdecreases expression 18289764
C016601 4-hydroxytamoxifen 4-hydroxytamoxifen results in decreased expression of MGP mRNAdecreases expression 16514628
C014949 acetylhydrazine acetylhydrazine results in decreased expression of MGP mRNAdecreases expression 15282401
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MGP mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of MGP mRNAincreases expression 20458559
D001414 Bacitracin Bacitracin results in increased expression of MGP mRNAincreases expression 18289764
C447119 bazedoxifene acetate bazedoxifene acetate results in decreased expression of MGP mRNAdecreases expression 19914376
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MGP mRNAaffects cotreatment|increases expression 18164116
C031463 beta-glycerophosphoric acid beta-glycerophosphoric acid results in decreased expression of MGP mRNAdecreases expression 17171500
C031463 beta-glycerophosphoric acid Calcitriol promotes the reaction [beta-glycerophosphoric acid results in decreased expression of MGP mRNA]decreases expression|increases reaction 17171500
C031463 beta-glycerophosphoric acid paricalcitol promotes the reaction [beta-glycerophosphoric acid results in decreased expression of MGP mRNA]decreases expression|increases reaction 17171500
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of MGP mRNAdecreases expression 15336504
12766906
D002104 Cadmium Cadmium results in increased expression of MGP mRNAincreases expression 17327699
D019256 Cadmium Chloride Cadmium Chloride results in increased expression of MGP mRNAincreases expression 17327699
D002118 Calcium Calcium binds to MGP proteinaffects binding 18369157
D002118 Calcium [Calcium binds to MGP protein] which binds to and results in decreased activity of BMP4 proteinaffects binding|decreases activity 18369157
D002118 Calcium Edetic Acid inhibits the reaction [Calcium binds to MGP protein]affects binding|decreases reaction 18369157
D002118 Calcium [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein]affects binding|decreases reaction 18369157
D002118 Calcium Calcium affects the expression of MGP mRNAaffects expression 15913539
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of MGP mRNAaffects expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of MGP mRNAincreases expression 16239168
D002794 Choline Choline affects the expression of MGP mRNAaffects expression 17616785
C030123 coumarin coumarin results in decreased expression of MGP mRNAdecreases expression 19350115
C030123 coumarin coumarin results in decreased expression of MGP mRNAdecreases expression 19350115
D016572 Cyclosporine Cyclosporine results in decreased expression of MGP mRNAdecreases expression 20106945
D003993 Dibutyl Phthalate Dibutyl Phthalate results in increased expression of MGP mRNAincreases expression 15829613
D002945 Cisplatin Cisplatin results in increased expression of MGP mRNAincreases expression 18289764
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MGP mRNAaffects cotreatment|increases expression 18164116
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of MGP mRNAincreases expression 19638242
D002117 Calcitriol Calcitriol promotes the reaction [beta-glycerophosphoric acid results in decreased expression of MGP mRNA]decreases expression|increases reaction 17171500
D004492 Edetic Acid Edetic Acid inhibits the reaction [Calcium binds to MGP protein]affects binding|decreases reaction 18369157
D004492 Edetic Acid [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein]affects binding|decreases reaction 18369157
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of MGP mRNAaffects cotreatment|decreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of MGP mRNAincreases expression 16202921
16514628
19619570
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of MGP mRNAdecreases expression 19400957
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of MGP mRNAdecreases expression 12655037
17557909
19400957
D012968 Etidronic Acid Etidronic Acid results in increased expression of MGP mRNAincreases expression 17270170
C070081 fulvestrant fulvestrant results in decreased expression of MGP mRNAdecreases expression 16514628
D005839 Gentamicins Gentamicins results in increased expression of MGP mRNAincreases expression 18289764
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of MGP mRNAaffects cotreatment|increases expression 17183730
D007654 Ketoconazole Ketoconazole affects the expression of MGP mRNAaffects expression 18289764
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in increased expression of MGP mRNAincreases expression 18289764
C084656 paricalcitol paricalcitol promotes the reaction [beta-glycerophosphoric acid results in decreased expression of MGP mRNA]decreases expression|increases reaction 17171500
C084656 paricalcitol [Phosphorus co-treated with paricalcitol] results in increased expression of MGP mRNAaffects cotreatment|increases expression 17715259
C076994 perfluorooctane sulfonic acid perfluorooctane sulfonic acid results in increased expression of MGP mRNAincreases expression 17560707
D010758 Phosphorus [Phosphorus co-treated with paricalcitol] results in increased expression of MGP mRNAaffects cotreatment|increases expression 17715259
C035988 procymidone procymidone results in increased expression of MGP mRNAincreases expression 15686871
D011374 Progesterone Progesterone results in decreased expression of MGP mRNAdecreases expression 18070364
D020849 Raloxifene Raloxifene results in decreased expression of MGP mRNAdecreases expression 16514628
D012643 Selenium Selenium results in increased expression of MGP mRNAincreases expression 18583539
D013629 Tamoxifen Tamoxifen results in decreased expression of MGP mRNAdecreases expression 19400957
D013629 Tamoxifen Tamoxifen results in decreased expression of MGP mRNAdecreases expression 19400957
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of MGP mRNAaffects cotreatment|decreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of MGP mRNAdecreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of MGP mRNAdecreases expression 11752688
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of MGP mRNAincreases expression 17982090
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of MGP mRNAaffects cotreatment|increases expression 17183730
D014640 Vancomycin Vancomycin results in increased expression of MGP mRNAincreases expression 18289764
C025643 vinclozolin vinclozolin affects the expression of MGP mRNAaffects expression 19015723
D014810 Vitamin E Vitamin E results in increased expression of MGP mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.0614745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.7415322242 14514962 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 6.748875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.5019490988
MESH:D000138 Acidosis Ammonium Chloride 3.0818287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.4617505938
MESH:D058186 Acute Kidney Injury Cisplatin 7.7317670903 15814532 12690470
MESH:D058186 Acute Kidney Injury Gentamicins 7.7311274264
MESH:D000230 Adenocarcinoma arsenic trioxide 8.9911798837 19825857
MESH:D000230 Adenocarcinoma Cisplatin 8.9917638652 11798837
MESH:D000230 Adenocarcinoma Estradiol 8.9911473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 8.9914692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 9.543712494
MESH:D000236 Adenoma beta-Naphthoflavone 9.5419389873
MESH:D000236 Adenoma Diethylnitrosamine 9.546695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 8.4717162532 19052882 16434500 19061943 18056438 17620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.4716835633
MESH:D000419 Albuminuria Raloxifene 4.1417308373 17451421
MESH:D000544 Alzheimer Disease Raloxifene 2.4315800139
MESH:D000550 Amblyopia Valproic Acid 4.7517688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.5411748828
MESH:D001008 Anxiety Disorders Valproic Acid 7.6017497229
MESH:D001008 Anxiety Disorders vinclozolin 7.6019015723
OMIM:109730 AORTIC VALVE DISEASE marker/mechanism 19350115
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.0011256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.3615885639
MESH:D050197 Atherosclerosis Cadmium 3.3515687053
MESH:D001284 Atrophy fulvestrant 4.4011514358
MESH:D001321 Autistic Disorder Choline 2.5716818868
MESH:D001321 Autistic Disorder Valproic Acid 2.5718940202 17507914 18177632 18316065 17157402 20603192 18396377 15238991 19232924 19460635 18558336 18985861 18775368 16609825 17688650
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.5311289319 1440618
MESH:D001714 Bipolar Disorder Valproic Acid 2.8217594078 20046352
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 7.5516206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 7.5512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 6.9715746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 6.978888407
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.4014601052
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.8517868700
MESH:D001930 Brain Injuries Progesterone 9.4215665606 15845082 15380490
MESH:D001930 Brain Injuries Raloxifene 9.4216580743
MESH:D001943 Breast Neoplasms Calcitriol 5.2411237771
MESH:D001943 Breast Neoplasms Cisplatin 5.2419526202 18382427
MESH:D001943 Breast Neoplasms Diethylnitrosamine 5.2417474063
MESH:D001943 Breast Neoplasms Estradiol 5.2412948864 14630087 17289903 17261762 19861407 16675129 18497071 17018787
MESH:D001943 Breast Neoplasms fulvestrant 5.2418984771
MESH:D001943 Breast Neoplasms Progesterone 5.2415562024 16175315 17614352
MESH:D001943 Breast Neoplasms Raloxifene 5.2415775269 17440819 17242785 15758505 17049068 15572757 16837676 17893378 17595753 17952589 16912660 17261762
MESH:D001943 Breast Neoplasms Tamoxifen 5.2420390343 19115204 19244106 19189212 18821012 19142967 19487384 11161223 20005174 19189210 18425577 18629630 20859285 17242785 19410462 20135344 19288272 19084267 21138602 17893378 19066611 18815881 16873071 20544844 18997820 15565566 17261762 19221464 17049068 19059307 15668708 19155303 21152245 16202921 16818667 18351453 19289846 18855134 20065188 19011961 17440819 16273361 18984771 19103187 19200415
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.2420435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.8911589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.9916111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 8.393786805 15700767 18705752 15721981 16192424 16227642 16011737 15673190 10355542 16124888 16097048 16050911
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 8.3916050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.4216835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.0419066611
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 15.2116705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 15.217296757 3581430
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 15.2114691202 15073043 16217749 11135700 15553829
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 15.2118788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 15.2117982673
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 15.2117761372 17428255 16502159 19701751 18788625 21159647 16681979 16807293 18971187 18978308 17173139 20101231 19919837 18785209 19171122 19335982 16328049 17162532 17978847 20084675 16935385 3581430 19208518 19394651 20432363 19519916 16878318 16779866 16288022 20512989 18665156 16698587 18210153 20524982 10672840 20007298 19052882 16830150 18056438 19822196 16569478 18494052 17138121 16540662 20727157 11831363 10737359 20935162 20214788 19107877 18691550 19383236 18506893 20514400 18393292 19539802 19418558 3084413 17055752
MESH:D006528 Carcinoma, Hepatocellular Estradiol 15.2116924424
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 15.2116924424
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.8612023789 16685392
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.3919014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.447296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.7012490120
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 4.4411237771
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 4.4417066447 6189445 18337622
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 8.1317572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 8.1317572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.0916120746 18670907 18850075
MESH:D002318 Cardiovascular Diseases Raloxifene 3.1115775269
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 22.026135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 22.027505956
MESH:D002471 Cell Transformation, Neoplastic Cadmium 22.0217332340
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 22.0212371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 22.0217174075 21159647 7505956 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 22.0218566989
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.5220734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.9919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.9916835633
MESH:D002761 Cholangitis 1-Naphthylisothiocyanate 5.7112912871
MESH:D002779 Cholestasis 1-Naphthylisothiocyanate 16.3612927374 15500046 7624871 15913567 16629650 19486331 18590720 18164287
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 16.3619486331 9022650
MESH:D002779 Cholestasis Cyclosporine 16.3619486331
MESH:D002779 Cholestasis Ethinyl Estradiol 16.3615861022 11677210 16919318 17333356 16105132 17681005 17110522
MESH:D002780 Cholestasis, Intrahepatic 1-Naphthylisothiocyanate 5.3719407337 10220858
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.8916354765 8697196 12621046 15340226 15668235
MESH:D003072 Cognition Disorders Raloxifene 4.1515800139
MESH:D003092 Colitis Selenium 8.2717936198
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 8.2718200517 17991707 16782535 16867261 11698051 17936198 16474422 18023891 16804969
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 3.2717276891
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.5320501625
MESH:D015179 Colorectal Neoplasms Cisplatin 2.5315273666
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.6614669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.7312609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 4.8610525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.8610048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Valproic Acid 4.8617688650 8888407 16575769
MESH:D019465 Craniofacial Abnormalities Vitamin E 4.8619769572
MESH:D003456 Cryptorchidism Dibutyl Phthalate 10.1916037377
MESH:D003456 Cryptorchidism vinclozolin 10.1914966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.5518551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.6615213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.9019031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.7617474826
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.3712868966 11906362 18759878 14531868 8156756 2524372 8970840 11298694
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.052952479 3621924
MESH:D002658 Developmental Disabilities Choline 4.3516818868
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 6.3719647726
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.3720387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.3717107852
MESH:D003928 Diabetic Nephropathies Estradiol 12.7019279558
MESH:D003928 Diabetic Nephropathies Raloxifene 12.7017308373 17451421 15920148
MESH:D003928 Diabetic Nephropathies Tamoxifen 12.7019279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.0317187935
MESH:D056486 Drug-Induced Liver Injury 1-Naphthylisothiocyanate 22.6217522070 7624871 18289764 20133375
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 22.6221346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 22.626482804 6679447 18648102 18289764 11289319 18692083 8291058 16192314 1440618 7440962 9022650 9653073 9328219
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 22.623786805 19085960 15968718 7440962 7120509 2869522 15998439 16177239 15027814 10092053 11566570 6884620 7179309 21278145 6623471 16227642 3732212 10915739 19336974 17522070 9327722 4309450
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 22.6219107877
MESH:D056486 Drug-Induced Liver Injury Ketoconazole 22.6218289764
MESH:D056486 Drug-Induced Liver Injury Selenium 22.6215131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 22.6220420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 22.621733752 19641884
MESH:D004362 Drug Toxicity Cisplatin 11.8112649298 12231392 19839026 15033597
MESH:D004362 Drug Toxicity Gentamicins 11.8115033597 11033412
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 11.8111462148
MESH:D004421 Dystonia Valproic Acid 3.611851702
MESH:C538011 Eales disease Vitamin E 4.229068938
MESH:D004487 Edema Raloxifene 5.4715860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.4712711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.4215322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 23.9415138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 23.9412538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 23.9417692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 23.9415845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 23.9419031437
MESH:D016889 Endometrial Neoplasms 4-hydroxytamoxifen 10.7019148513
MESH:D016889 Endometrial Neoplasms Estradiol 10.7011473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 10.7019155303 20544844 17893378 16202921
MESH:D004715 Endometriosis Progesterone 7.5616134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.569294722 10568697
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 3.693659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 3.4316628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.6818234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.197562514 6254150 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 3.837750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.593659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6316302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 6.463581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.4612903497
MESH:D004938 Esophageal Neoplasms Cisplatin 6.4615464296 17638652 15173087 16481741 16785472
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.6511564622
MESH:D005234 Fatty Liver arsenic trioxide 35.8715073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 35.8761145 19224547 12795759 15959796 12631006 16045604 17595544 16239168
MESH:D005234 Fatty Liver Cyclosporine 35.8719224547
MESH:D005234 Fatty Liver Diethylnitrosamine 35.8721071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 35.8715345470
MESH:D005234 Fatty Liver Raloxifene 35.8717473493
MESH:D005234 Fatty Liver Tamoxifen 35.8714986274 19224547
MESH:D005234 Fatty Liver Valproic Acid 35.8719224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.9416709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.9911858732
MESH:D005315 Fetal Diseases Valproic Acid 4.4016575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.688888407 18558336
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.536705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.0514745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.7119069698
MESH:D005355 Fibrosis Carbon Tetrachloride 17.3618705752
MESH:D005355 Fibrosis Cyclosporine 17.3612639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 17.3620067830
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 17.3617994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.8116904648
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.4616973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.8116417039
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.748708960
MESH:D005909 Glioblastoma perfluorooctane sulfonic acid 3.9517162496
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.607505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1110696789
MESH:D006258 Head and Neck Neoplasms Cisplatin 3.3915102660 15464296
MESH:D034381 Hearing Loss Cisplatin 8.9519898482
MESH:D034381 Hearing Loss Gentamicins 8.9518024279 19130971 15968427 17868369
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.0315464296
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.6810048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 5.6816080930
MESH:D006331 Heart Diseases Raloxifene 3.2011110106
MESH:D006333 Heart Failure Selenium 2.7717162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9415720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9111000095
MESH:D006505 Hepatitis 1-Naphthylisothiocyanate 13.1818590720
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 13.186705139
MESH:D006505 Hepatitis Carbon Tetrachloride 13.1819110552 19900420
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.4412621046 15340226 16120746
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.5216490937 16863852
MESH:D006558 Herpes Genitalis Estradiol 4.5515709030
MESH:D006689 Hodgkin Disease Cisplatin 3.2116170182 16200630
MESH:D019584 Hot Flashes Estradiol 8.4417088409
MESH:D019584 Hot Flashes Vitamin E 8.4414716179
MESH:D006849 Hydrocephalus Valproic Acid 4.3917688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.5615340226 16959395 8697196 16354765 18606429
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.0516899240
MESH:D053565 Hypercalciuria Gentamicins 5.2317652376
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.4715034207
MESH:D006973 Hypertension Cyclosporine 7.4010903974
MESH:D006973 Hypertension Raloxifene 7.4017577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.4018850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.6215338365
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.1616612254
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3416569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.9415869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 9.4217937319
MESH:D007248 Infertility, Male fulvestrant 9.4211514358
MESH:D007248 Infertility, Male vinclozolin 9.4216467254
MESH:D007249 Inflammation Diethylnitrosamine 9.7718785209
MESH:D007249 Inflammation Progesterone 9.7715869954
MESH:D007249 Inflammation Tamoxifen 9.7719457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 9.7712878042 12200463
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 3.3718200517
MESH:D007251 Influenza, Human Selenium 9.3416624496
MESH:D007251 Influenza, Human Vitamin E 9.3416624496
MESH:D007333 Insulin Resistance Estradiol 2.6516627594 16393666
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 4.1417994277
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.538074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.9116580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.9515604871
MESH:C536167 Keutel syndrome marker/mechanism
MESH:D007673 Kidney Cortex Necrosis Cisplatin 11.7015464296
MESH:D007673 Kidney Cortex Necrosis Gentamicins 11.7018842672
MESH:D007674 Kidney Diseases Bacitracin 33.5318289764
MESH:D007674 Kidney Diseases Cadmium 33.5316226777 16962696 16322080
MESH:D007674 Kidney Diseases Cadmium Chloride 33.5316962696
MESH:D007674 Kidney Diseases Cisplatin 33.5319839026 18289764 12231392 12649298 15190930
MESH:D007674 Kidney Diseases Cyclosporine 33.538314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 33.5315618244
MESH:D007674 Kidney Diseases Gentamicins 33.5317934191 18289764 19349640
MESH:D007674 Kidney Diseases Vancomycin 33.5318289764
MESH:D007674 Kidney Diseases Vitamin E 33.5312488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.4616518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 19.2216705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 19.226582329
MESH:D007680 Kidney Neoplasms Cyclosporine 19.2212371664
MESH:D007680 Kidney Neoplasms Estradiol 19.2215610895
MESH:D007680 Kidney Neoplasms Tamoxifen 19.2218625569
MESH:D007683 Kidney Tubular Necrosis, Acute Calcium 17.0216316344
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 17.0211231351
MESH:D007683 Kidney Tubular Necrosis, Acute Gentamicins 17.0211231351
MESH:D007889 Leiomyoma Raloxifene 4.0616973256
MESH:D016773 Leishmaniasis, Cutaneous Gentamicins 7.8810219319
MESH:D016773 Leishmaniasis, Cutaneous Ketoconazole 7.881311351 8889330 19744259 2166429
MESH:D007898 Leishmaniasis, Visceral Ketoconazole 4.1811332679
MESH:D007938 Leukemia arsenic trioxide 2.5815070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.3712560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.8316972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.0714633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.3419077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.5616467208 17050201 19850784 20471514 16968895
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 3.5617596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 2.9019225113 17107899 17217047 12712474 17869043 12018890 11161223 11468182 15748426 16891316 19075265 16112521 15336539 19642359 16331271 9834237 15622746 17712046 12679006 19035177 16330433 16823087 16966277 17649720 15213294
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.9016882451
MESH:D007984 Leydig Cell Tumor vinclozolin 4.2516417039
MESH:D008064 Lipidoses Ketoconazole 7.1517567588
MESH:D008064 Lipidoses Tamoxifen 7.1515342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 5.6916221502 16943688 16239168 11408273 17157831 17174718 17334410 11903743 21278145
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 5.6918407596 19638242 18665156 20032147 18522880
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.8915034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 5.9418006644 18339082 12649538 18420326 16136751 18187930 14512876 15931870 15925388 12609069 18412020 15123356 14716496 14716833 17869086 18481824 14620537 15052691 15818738 17900296 18277467 18166357 12632514 16097048 18472332 16027843 12667390 17766677 15370692 18205269 12898905 16011737 17481882 17565644 17557913 18317297 18472094 17944888 15673190 18395095 16248980 16116963 18395914 15057751 12389079 18705752 18054572 18279442 14748882 15996030 17922224 18263696 15338365 12632512 17525996 16192424 18418968 16033810 12445418 10355542 18376398 17631135 15876570 14724832 17761835 17721639 17805973 12741479 16015684 15959796 17714472 18429990 18156304 12586293 17640975 15650968 15730626 15893842 17823541 16638106 12445421 11481614 17708605 17976157 12666154 20821823 12546737 15362042 13678700 12958196 18251166 18210741 17698563
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 5.9414659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 5.9418564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 5.9412878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 5.9416169303
MESH:D008107 Liver Diseases 1-Naphthylisothiocyanate 5.8317184895
MESH:D008107 Liver Diseases Carbon Tetrachloride 5.8316964402 16246199 15720792 17285989 15830285
MESH:D008107 Liver Diseases Diethylnitrosamine 5.8317034775
MESH:D017093 Liver Failure Carbon Tetrachloride 3.7015123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.2816899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 18.787678174
MESH:D008113 Liver Neoplasms arsenic trioxide 18.7814682389
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 18.7819389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 18.7819294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 18.7821278145 20452335 9163691 20101389 19833225 2422723 19850985 20137499 19499222 18754104 19642983 19254457 21047994 12771043 21071580 19690152 19638242 19812893 20405173 12112319 21167192 15175105 19427195 19090486 20492335 18978307 10737359 18648771 16942905 19551842 2862719 20501860 20434301 19294768 19426721 18977376 15885732 18644402 20583210 20118626 19996281 19255062 19256749 19073162
MESH:D008113 Liver Neoplasms Tamoxifen 18.7816684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 18.7816984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 23.542876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 23.543712494 6587162 598648 1399818
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 23.5420377131
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 23.5418164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 23.5412014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 23.5421159647 19004024 18308698 16267830 19126423 2563599 3124819 18544905 16842330 18775883 18253720 19539802 17942915 19009564 17854601 17174075 18282651 18079962 18093689 19519916 9362446 18164116
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 23.5412151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.9915213294
MESH:D008171 Lung Diseases Vitamin E 2.8516863852
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 3.7817228818
MESH:D008175 Lung Neoplasms arsenic trioxide 7.5911798837 19825857
MESH:D008175 Lung Neoplasms Cisplatin 7.5911798837 17225452 6189445
MESH:D008175 Lung Neoplasms Diethylnitrosamine 7.5920970405 6695378 20512841 21163286
MESH:D008175 Lung Neoplasms Tamoxifen 7.5918625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 7.5919555203 11884234
MESH:D008175 Lung Neoplasms Vitamin E 7.5911062179
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.2919428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 11.6816891317 17203775 11807958 11408345
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 11.6817203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Selenium 11.6815318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 11.6814580682 16827153 11731420 19196723 19196722
MESH:D020149 Manganese Poisoning Estradiol 11.0319453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.0319453300
MESH:D008545 Melanoma Cisplatin 3.1618176117 18505091 12883367 17761969 11135225 16809738 12393984 15577323 18332650 17023156 12374674 16248763 16432458
MESH:D008545 Melanoma Tamoxifen 3.1612393984 19393235
MESH:D018328 Melanoma, Amelanotic Cisplatin 9.9215990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 9.9215990972
MESH:D008654 Mesothelioma Cisplatin 5.6617638057
MESH:D008654 Mesothelioma Selenium 5.6615107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.3016801185
MESH:D008881 Migraine Disorders Valproic Acid 2.8518765137 18803445
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.0715863610
MESH:D009101 Multiple Myeloma arsenic trioxide 6.2715949261 19417148 14977855 19549372 11468182
MESH:D009101 Multiple Myeloma Raloxifene 6.2716497877
MESH:D009137 Muscular Dystrophy, Animal Gentamicins 5.7918694830
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.608888407
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.1918349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.4716882451 16105982
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 6.4717596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6412213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 2.9116810080
MESH:D009232 Myxoma Raloxifene 5.0716343187
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.397678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.5116624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 8.233581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.233581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 8.2319393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3519410462
MESH:D009369 Neoplasms Cisplatin 2.7116773208
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.5219196722 19189210 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.2617289903
MESH:D009395 Nephritis, Interstitial Cisplatin 4.0115464296
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.9517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.8818481113 19348381
MESH:D009421 Nervous System Malformations Estradiol 7.9616427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 7.9614600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 10.286679447
MESH:D009436 Neural Tube Defects arsenic trioxide 10.2810525206
MESH:D009436 Neural Tube Defects Valproic Acid 10.2816359493 8888407
MESH:D009447 Neuroblastoma Cisplatin 3.198761367
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 2.9620387270
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.228761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6320387270
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 7.5116049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 7.516482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.533988306
MESH:D010024 Osteoporosis Calcium 10.6317882678
MESH:D010024 Osteoporosis Etidronic Acid 10.6317042918
MESH:D010024 Osteoporosis Raloxifene 10.6317882678 15775268 19059307
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 3.7915579764 17823083 15758505 17893378
MESH:D010051 Ovarian Neoplasms arsenic trioxide 9.8912452020 16624393 19769630
MESH:D010051 Ovarian Neoplasms Cisplatin 9.8917225452 15464296 6897625 19769630
MESH:D010051 Ovarian Neoplasms Estradiol 9.8919401270
MESH:D010051 Ovarian Neoplasms Progesterone 9.8917393432 16525653
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 7.5615580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 7.5619003803
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 7.5616540662
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 3.7717698068
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2511578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.027296757
MESH:D010235 Paraganglioma arsenic trioxide 3.7219927285
MESH:D010382 Peliosis Hepatis 1-Naphthylisothiocyanate 12.1720133375
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 12.1712520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.8615464296
MESH:D016491 Peripheral Vascular Diseases Cadmium 4.9115687053
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 3.986228378
MESH:D010954 Plasmacytoma Selenium 4.4015087411
MESH:D010997 Pleural Neoplasms Cisplatin 4.8617638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1118163543
MESH:D011230 Precancerous Conditions Cyclosporine 7.6112371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 7.612563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 13.4811896295 11118676 11399792 11222880
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 13.4820603192
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 13.4818220299 18042343 19015723
MESH:D011469 Prostatic Diseases vinclozolin 4.4618220299
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.3015572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.4620887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.3119131511
MESH:D011471 Prostatic Neoplasms Cadmium 2.3117075824
MESH:D011471 Prostatic Neoplasms Calcitriol 2.3112479363 16289102 18247401 16644109 15754350
MESH:D011471 Prostatic Neoplasms Estradiol 2.3116740699
MESH:D011471 Prostatic Neoplasms Ketoconazole 2.3117404083
MESH:D011471 Prostatic Neoplasms Raloxifene 2.3116220300 16536755 15731164
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.3115067354
MESH:D011471 Prostatic Neoplasms Vitamin E 2.3115084515
MESH:D011472 Prostatitis vinclozolin 4.4618629315
MESH:D011507 Proteinuria Gentamicins 4.2915033597
MESH:D011537 Pruritus Ethinyl Estradiol 2.8415861022 16919318
MESH:D019310 Pseudolymphoma Valproic Acid 4.0612752131 11422049
MESH:D011565 Psoriasis Cyclosporine 2.0516882103
MESH:D011693 Purpura Raloxifene 5.0715770314
MESH:D051437 Renal Insufficiency Cisplatin 9.1215464296
MESH:D051437 Renal Insufficiency Gentamicins 9.1215728788 17132701
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.3818990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.023692021
MESH:D012173 Retinitis Gentamicins 5.7918644591
MESH:D012208 Rhabdomyosarcoma Valproic Acid 3.7319155313
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.6718045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 8.8416646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 8.8414601052
MESH:D012559 Schizophrenia Valproic Acid 2.0019110320 15737665
MESH:D012640 Seizures 2,6-dinitrotoluene 4.8618551238
MESH:D012640 Seizures Valproic Acid 4.861511512 11738929 15475178 16876388 3137016 17978042 14763951 11044598
MESH:D012871 Skin Diseases Vitamin E 2.3118709164
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 4.798532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 4.7916192470
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.8615464296
MESH:D013088 Spermatocele Ethinyl Estradiol 9.9416709447
MESH:D013088 Spermatocele Tamoxifen 9.9416709447
MESH:D013119 Spinal Cord Injuries Progesterone 9.2915862959 16503802
MESH:D013119 Spinal Cord Injuries Tamoxifen 9.2919457130
MESH:D016135 Spinal Dysraphism Valproic Acid 3.4119490988
MESH:D013226 Status Epilepticus Valproic Acid 4.0612833885
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.1317007042
MESH:D013274 Stomach Neoplasms Cisplatin 3.1315958060 17522103 18396642
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.1318456281
MESH:D020521 Stroke Raloxifene 7.4516837676
MESH:D020521 Stroke Vitamin E 7.4516517955
MESH:D013736 Testicular Neoplasms Cisplatin 4.1917225452 15464296
MESH:D013921 Thrombocytopenia 1-Naphthylisothiocyanate 4.3420133375
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.1811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7515669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4212697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 9.857505956 1399818 6587162 6582329 3712494
MESH:D013964 Thyroid Neoplasms arsenic trioxide 9.8519014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 9.857505956
MESH:D013978 Tibial Fractures Estradiol 12.0919048282
MESH:D013978 Tibial Fractures Raloxifene 12.0919048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.4915213294
MESH:D014178 Translocation, Genetic Valproic Acid 4.7517262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.043119515
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 17.1716049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 17.178074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 17.1712973940 20435036 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 17.1715464296 17225452 12973940
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 17.1717572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 17.1716712894 17572228 8653321
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.188888407
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 3.8410091137
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 3.8016803524
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.8514692618
MESH:D014605 Uveitis Cyclosporine 3.501336536
MESH:D014625 Vaginal Neoplasms Cisplatin 4.1515577323
MESH:D014648 Varicose Veins marker/mechanism 17643059
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1112125929
MESH:D014689 Venous Insufficiency coumarin 5.2912708602
MESH:D054556 Venous Thromboembolism Raloxifene 4.7216837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1114671159 15869587
MESH:D015837 Vestibular Diseases Gentamicins 5.0718776599
MESH:D014839 Vomiting Cisplatin 4.2311897121
MESH:D014846 Vulvar Neoplasms Raloxifene 5.0716343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.7615886252
MESH:D014985 Xerophthalmia Cyclosporine 3.9517120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA30790
    • Releated gene ID Related gene Name
    PA30790MGP
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    PA447054Stroke
    Releated drug ID Related drug Name
    PA451906warfarin
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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