AutismKB 2.0

Annotation Detail for MGST1


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Basic Information Top
Gene Symbol:MGST1 ( GST12,MGC14525,MGST,MGST-I )
Gene Full Name: microsomal glutathione S-transferase 1
Band: 12p12.3
Quick LinksEntrez ID:4257; OMIM: 138330; Uniprot ID:MGST1_HUMAN; ENSEMBL ID: ENSG00000008394; HGNC ID: 7061
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-4061glutathione-mediated detoxification
Pathway IDPathway Name
hsa00480Glutathione metabolism
hsa00980Metabolism of xenobiotics by cytochrome P450
hsa00982Drug metabolism - cytochrome P450
Pathway IDPathway Name
Biological oxidations
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1903Larynx cancer
Desease Name
colorectal cancer
CANCER
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C404910 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of MGST1 mRNAincreases expression 11509743
C404910 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane [Estradiol co-treated with 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane] results in increased expression of MGST1 mRNAaffects cotreatment|increases expression 11509743
C079315 2-(4-(quinolin-2-yl-methoxy)phenyl)-2-cyclopentylacetic acid 2-(4-(quinolin-2-yl-methoxy)phenyl)-2-cyclopentylacetic acid results in decreased activity of MGST1 proteindecreases activity 9890956
C096092 2-(acetoxyamino)-1-methyl-6-phenylimidazo(4,5-b)pyridine MGST1 protein affects the metabolism of and results in decreased activity of 2-(acetoxyamino)-1-methyl-6-phenylimidazo(4,5-b)pyridineaffects metabolic processing|decreases activity 8069858
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of MGST1 mRNAdecreases expression 12958071
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of MGST1 mRNAdecreases expression 18648102
C122155 6-bromoacetyl-2-dimethylaminonaphthalene MGST1 protein affects the metabolism of [6-bromoacetyl-2-dimethylaminonaphthalene co-treated with Glutathione]affects cotreatment|affects metabolic processing 12470677
C478192 6-chloroacetyl-2-dimethylaminonaphthalene MGST1 protein affects the metabolism of 6-chloroacetyl-2-dimethylaminonaphthaleneaffects metabolic processing 12470677
D000082 Acetaminophen Acetaminophen results in decreased expression of MGST1 mRNAdecreases expression 11793227
D000082 Acetaminophen Acetaminophen affects the expression of MGST1 mRNAaffects expression 17562736
C038518 acrylodan MGST1 protein affects the metabolism of [acrylodan co-treated with Glutathione]affects cotreatment|affects metabolic processing 12470677
D000638 Amiodarone Amiodarone results in increased expression of MGST1 mRNAincreases expression 19774075
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MGST1 mRNAaffects expression 16483693
D003913 Dextroamphetamine Dextroamphetamine results in increased expression of MGST1 mRNAincreases expression 16715494
D001151 Arsenic Arsenic results in increased expression of MGST1 mRNAincreases expression 19945496
C071435 BAY u9773 BAY u9773 results in decreased activity of MGST1 proteindecreases activity 9890956
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of MGST1 mRNAincreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of MGST1 mRNAincreases expression 17944540
C006780 bisphenol A bisphenol A results in decreased expression of MGST1 mRNAdecreases expression 12075121
D002087 Butyrates Butyrates results in increased expression of MGST1 mRNAincreases expression 14674679
D002110 Caffeine Caffeine results in decreased expression of MGST1 mRNAdecreases expression 11793227
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of MGST1 mRNAdecreases expression 15056808
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of MGST1 mRNAaffects expression 17805973
12734012
C099555 CD 437 CD 437 results in decreased expression of MGST1 mRNAdecreases expression 12958071
D002713 Chlorine Chlorine results in decreased expression of MGST1 mRNAdecreases expression 18636392
D002713 Chlorine [Ozone co-treated with Chlorine] affects the expression of MGST1 mRNAaffects cotreatment|affects expression 18636392
D003474 Curcumin Curcumin results in increased expression of MGST1 mRNAincreases expression 18299980
D003520 Cyclophosphamide Cyclophosphamide results in decreased expression of MGST1 mRNAdecreases expression 11906922
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of MGST1 mRNAaffects cotreatment|increases expression 16054899
D003907 Dexamethasone EGF protein inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of MGST1 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D003907 Dexamethasone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of MGST1 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D003976 Diazinon Diazinon results in increased expression of MGST1 mRNAincreases expression 19440498
C121718 dicyclanil dicyclanil results in increased expression of MGST1 mRNAincreases expression 15664270
D004041 Dietary Fats Dietary Fats results in decreased expression of MGST1 mRNAdecreases expression 18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MGST1 mRNAaffects cotreatment|decreases expression 18544905
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid] results in increased expression of MGST1 mRNAaffects cotreatment|increases expression 18544905
D004052 Diethylnitrosamine [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of MGST1 proteinaffects cotreatment|increases expression 20935162
D004958 Estradiol [Estradiol co-treated with 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane] results in increased expression of MGST1 mRNAaffects cotreatment|increases expression 11509743
D004958 Estradiol [Estradiol co-treated with Methoxychlor metabolite] results in increased expression of MGST1 mRNAaffects cotreatment|increases expression 11509743
D004958 Estradiol Estradiol results in increased expression of MGST1 mRNAincreases expression 11509743
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of MGST1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of MGST1 mRNAdecreases expression 17942748
16174780
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of MGST1 mRNAaffects cotreatment|decreases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of MGST1 mRNAdecreases expression 12075121
16174780
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of MGST1 mRNAincreases expression 17108234
D005485 Flutamide Flutamide results in decreased expression of MGST1 mRNAdecreases expression 11509743
D019833 Genistein Genistein results in decreased expression of MGST1 mRNAdecreases expression 12075121
D005978 Glutathione Glutathione binds to and results in increased activity of MGST1 proteinaffects binding|increases activity 9890956
D005978 Glutathione Leukotriene C4 inhibits the reaction [Glutathione binds to and results in increased activity of MGST1 protein]affects binding|decreases reaction|increases activity 9890956
D005978 Glutathione MGST1 protein affects the metabolism of [6-bromoacetyl-2-dimethylaminonaphthalene co-treated with Glutathione]affects cotreatment|affects metabolic processing 12470677
D005978 Glutathione MGST1 protein affects the metabolism of [acrylodan co-treated with Glutathione]affects cotreatment|affects metabolic processing 12470677
C071834 glycidamide glycidamide results in increased expression of MGST1 mRNAincreases expression 17822822
D007975 Leukotriene B4 Leukotriene B4 results in decreased activity of MGST1 proteindecreases activity 9890956
C031927 hydroquinone hydroquinone results in increased expression of MGST1 mRNAincreases expression 15452088
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of MGST1 mRNAaffects cotreatment|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine EGF protein inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of MGST1 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D015056 1-Methyl-3-isobutylxanthine Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of MGST1 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MGST1 mRNAaffects cotreatment|decreases expression 18544905
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid] results in increased expression of MGST1 mRNAaffects cotreatment|increases expression 18544905
D017999 Leukotriene E4 Leukotriene E4 results in decreased activity of MGST1 proteindecreases activity 9890956
D017572 Leukotriene A4 Leukotriene A4 results in decreased activity of MGST1 proteindecreases activity 9890956
D017997 Leukotriene C4 Leukotriene C4 binds to and results in decreased activity of MGST1 proteinaffects binding|decreases activity 9890956
D017997 Leukotriene C4 Leukotriene C4 inhibits the reaction [Glutathione binds to and results in increased activity of MGST1 protein]affects binding|decreases reaction|increases activity 9890956
D017998 Leukotriene D4 Leukotriene D4 results in decreased activity of MGST1 proteindecreases activity 9890956
D008731 Methoxychlor [Estradiol co-treated with Methoxychlor metabolite] results in increased expression of MGST1 mRNAaffects cotreatment|increases expression 11509743
D008731 Methoxychlor Methoxychlor metabolite results in increased expression of MGST1 mRNAincreases expression 11509743
C406082 monomethylarsonous acid monomethylarsonous acid results in increased expression of MGST1 mRNAincreases expression 19945496
D009151 Mustard Gas Mustard Gas results in increased expression of MGST1 mRNAincreases expression 18955075
15674843
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in decreased expression of MGST1 mRNAdecreases expression 17616710
D026422 S-Nitrosoglutathione S-Nitrosoglutathione affects the metabolism of MGST1 proteinaffects metabolic processing 16899233
D010126 Ozone [Ozone co-treated with Chlorine] affects the expression of MGST1 mRNAaffects cotreatment|affects expression 18636392
C041786 palm oil palm oil results in decreased expression of MGST1 mRNAdecreases expression 18042831
D010269 Paraquat Paraquat results in increased expression of MGST1 mRNAincreases expression 17935786
D010634 Phenobarbital [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of MGST1 proteinaffects cotreatment|increases expression 20935162
D010795 Phthalic Acids Phthalic Acids results in decreased expression of MGST1 mRNAdecreases expression 15728792
C006253 pirinixic acid pirinixic acid results in increased expression of MGST1 mRNAincreases expression 17426115
C052393 pobilukast pobilukast results in decreased activity of MGST1 proteindecreases activity 9890956
C047681 pranlukast pranlukast results in decreased activity of MGST1 proteindecreases activity 9890956
D011794 Quercetin Quercetin affects the expression of MGST1 mRNAaffects expression 18178720
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of MGST1 mRNAaffects cotreatment|increases expression 16054899
C089730 rosiglitazone EGF protein inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of MGST1 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
C089730 rosiglitazone Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of MGST1 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
C017947 sodium arsenite sodium arsenite results in increased expression of MGST1 mRNAincreases expression 20308225
D018038 Sodium Selenite Sodium Selenite results in decreased expression of MGST1 mRNAdecreases expression 16705456
D018038 Sodium Selenite Sodium Selenite results in increased expression of MGST1 mRNAincreases expression 18175754
D013629 Tamoxifen Tamoxifen affects the expression of MGST1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of MGST1 mRNAdecreases expression 17101203
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of MGST1 mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin NFE2L2 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of MGST1 mRNA]affects reaction|increases expression 19474220
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of MGST1 mRNAaffects cotreatment|decreases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of MGST1 mRNA]affects cotreatment|decreases reaction|increases expression 16054899
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of MGST1 mRNAincreases expression 19474220
D013853 Thioacetamide Thioacetamide results in decreased expression of MGST1 mRNAdecreases expression 11793227
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in increased expression of MGST1 mRNAincreases expression 15289447
C066340 tolcapone tolcapone binds to MGST1 proteinaffects binding 19783845
D014415 Tunicamycin Tunicamycin results in decreased expression of MGST1 mRNAdecreases expression 17127020
C025643 vinclozolin vinclozolin affects the expression of MGST1 mRNAaffects expression 19015723
C063449 zileuton zileuton results in decreased activity of MGST1 proteindecreases activity 9890956
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 3.8614745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 6.076195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.0711752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 2.8818287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 9.8117505938
MESH:D000152 Acne Vulgaris zileuton 9.8120436887
MESH:D055371 Acute Lung Injury Chlorine 11.8420601635
MESH:D055371 Acute Lung Injury pirinixic acid 11.8418653653
MESH:D055371 Acute Lung Injury zileuton 11.8417118201
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 8.2320127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 8.2311473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 8.2314692618
MESH:D000230 Adenocarcinoma Genistein 8.2311473722
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 4.8415814487
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 8.603712494
MESH:D000236 Adenoma Benzo(a)pyrene 8.606695378
MESH:D000236 Adenoma Diethylnitrosamine 8.6010737359 6695378
MESH:D018248 Adenoma, Liver Cell dicyclanil 25.5417162532
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 25.5417162532 18056438 17620307 16434500 19061943 19052882
MESH:D018248 Adenoma, Liver Cell Phenobarbital 25.5417620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 25.5416434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 25.5416835633
MESH:D011125 Adenomatous Polyposis Coli Leukotriene B4 4.8517942926
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.0115276417
MESH:D018246 Adrenocortical Adenoma Arsenic 11.4917306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 11.4916712894 17306315
MESH:D000382 Agricultural Workers' Diseases Diazinon 6.7416487989
MESH:D000382 Agricultural Workers' Diseases Paraquat 6.7411874814
MESH:D017109 Akathisia, Drug-Induced tolcapone 5.6011080934
MESH:D019973 Alcohol-Related Disorders Curcumin 4.3917887948
MESH:D000544 Alzheimer Disease Curcumin 7.7515590663
MESH:D000544 Alzheimer Disease Ozone 7.7515513908
MESH:D000544 Alzheimer Disease rosiglitazone 7.7519621015
MESH:D000544 Alzheimer Disease tolcapone 7.7520150427
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.3611748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.6317084956
MESH:D000799 Angioedema Acetaminophen 3.1510982225
MESH:D001008 Anxiety Disorders vinclozolin 3.0919015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.4119183758
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.2118218290 18057881 20041841
MESH:D020261 Arsenic Poisoning Arsenic 2.6312569548 16835338 18414634 16251483
MESH:D001161 Arteriosclerosis Cyclophosphamide 13.2515014928
MESH:D001161 Arteriosclerosis Dietary Fats 13.2515238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 13.2511256880
MESH:D001168 Arthritis Leukotriene B4 5.4911006272
MESH:D001169 Arthritis, Experimental Dexamethasone 5.8617659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 5.8615885639
MESH:D001172 Arthritis, Rheumatoid Curcumin 6.2916807698
MESH:D001172 Arthritis, Rheumatoid Ozone 6.2915570426
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 6.2919898480
MESH:D001249 Asthma Leukotriene B4 15.3611006272 19667530
MESH:D001249 Asthma Leukotriene D4 15.368222486 9690572
MESH:D001249 Asthma Mustard Gas 15.3610378619
MESH:D001249 Asthma Ozone 15.3616373670 17854713
MESH:D001249 Asthma pranlukast 15.3620332717
MESH:D001249 Asthma zileuton 15.368598621 19214143 10764316 17944539 9620945 10181070 20332717
MESH:D055963 Asthma, Aspirin-Induced pranlukast 5.3419667532
MESH:D001250 Asthma, Exercise-Induced Leukotriene B4 15.7419667531
MESH:D001250 Asthma, Exercise-Induced Leukotriene E4 15.7411953129
MESH:D001250 Asthma, Exercise-Induced zileuton 15.7410984370
MESH:D001260 Ataxia Telangiectasia Quercetin 4.3015336622
MESH:D050197 Atherosclerosis Arsenic 5.4412928151 19371607
MESH:D050197 Atherosclerosis Curcumin 5.4418704882
MESH:D001281 Atrial Fibrillation Amiodarone 3.3818651412 19698954
MESH:D001289 Attention Deficit Disorder with Hyperactivity Phthalic Acids 3.8820106747
MESH:D001321 Autistic Disorder Acetaminophen 2.2418445737
MESH:D001321 Autistic Disorder Glutathione 2.2419056591 16917939 18929414 19267885
MESH:D001327 Autoimmune Diseases Curcumin 8.6719761891
MESH:D001327 Autoimmune Diseases Quercetin 8.6719761891
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.3311289319 1440618
MESH:D001768 Blister Mustard Gas 4.4819167455
MESH:D001778 Blood Coagulation Disorders Amiodarone 16.9819483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 16.9819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 16.9812125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 16.9819483382
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.1015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.2915746008
MESH:D001862 Bone Resorption bisphenol A 3.2511985600
MESH:D001929 Brain Edema zileuton 5.1919309543
MESH:D002545 Brain Ischemia Curcumin 3.6616770732
MESH:D001932 Brain Neoplasms Curcumin 3.3517596214
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 6.9820146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 6.9817123778
MESH:D001943 Breast Neoplasms Curcumin 6.9819250217 18462866 18593918 16243823
MESH:D001943 Breast Neoplasms Cyclophosphamide 6.9817020986 18323546 17388661 15136595 18234424 16978400 11325840 12006526 15093573
MESH:D001943 Breast Neoplasms Dietary Fats 6.9820435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 6.9817474063
MESH:D001943 Breast Neoplasms Estradiol 6.9812948864 17261762 18497071 16675129 19861407 17018787 17289903 14630087
MESH:D001943 Breast Neoplasms Genistein 6.9816873071 17200150 16541309
MESH:D001943 Breast Neoplasms Quercetin 6.9818628248
MESH:D001943 Breast Neoplasms Tamoxifen 6.9819011961 16202921 15668708 16873071 19115204 18984771 19189212 17242785 17893378 19059307 19288272 21138602 17261762 16273361 15565566 19410462 19084267 19200415 18351453 19142967 18855134 19103187 19221464 21152245 20135344 20065188 19155303 20859285 18815881 17440819 20544844 20005174 19189210 18997820 20390343 18821012 11161223 19289846 18629630 16818667 17049068 19244106 19487384 18425577 19066611
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 6.9820435547
MESH:D016535 Bronchial Hyperreactivity Leukotriene B4 25.7512794006 12654629
MESH:D016535 Bronchial Hyperreactivity Leukotriene C4 25.7512654629
MESH:D016535 Bronchial Hyperreactivity Leukotriene D4 25.7512654629 12794006
MESH:D016535 Bronchial Hyperreactivity Leukotriene E4 25.7512654629
MESH:D016535 Bronchial Hyperreactivity Ozone 25.7517626835 18417511 19059883 15516495 16777450 18315731 14754758
MESH:D016535 Bronchial Hyperreactivity zileuton 25.7512654629 12794006 12388339
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.4815286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.2810378619 17687719
MESH:D002100 Cachexia Ozone 4.0616183385
MESH:D002105 Cadmium Poisoning Quercetin 4.8516962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.7816111702
MESH:D002252 Carbon Tetrachloride Poisoning 2-(4-(quinolin-2-yl-methoxy)phenyl)-2-cyclopentylacetic acid 8.5916033810
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 8.5916097048 15673190 16124888 15721981 18705752 15700767 16192424 10355542 16011737 16227642 3786805 16050911
MESH:D002277 Carcinoma Curcumin 6.4618593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.4616835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.1715504454 17687452
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.8419066611
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 31.223581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 31.223084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 31.2217306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 31.2218788625
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 31.2219701751
MESH:D006528 Carcinoma, Hepatocellular dicyclanil 31.2217162532
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 31.2216830150 17173139 20524982 16288022 20935162 16807293 18978308 18788625 18056438 18393292 20101231 19701751 20084675 20214788 18494052 19919837 16328049 18506893 16540662 19208518 11831363 19335982 16681979 18785209 19822196 17761372 20727157 17055752 19519916 16935385 19383236 18210153 19418558 16569478 19107877 17978847 16698587 19539802 17162532 10672840 18691550 17138121 20432363 19171122 18665156 19052882 20007298 3084413 18971187 19394651 17428255 16878318 21159647 3581430 16502159 20514400 16779866 20512989 10737359
MESH:D006528 Carcinoma, Hepatocellular Estradiol 31.2216924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 31.2216924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 31.2217173139 6705139 20007298 20935162 1701930
MESH:D006528 Carcinoma, Hepatocellular Quercetin 31.2219519916 12508355
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 31.2215276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 31.2216924424
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 31.2217997003
MESH:D002278 Carcinoma in Situ bisphenol A 4.3117123778
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 4.2116152834
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 4.9518414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 4.9511212258
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.2917234771
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 5.457296757
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 5.4516201981
MESH:D002294 Carcinoma, Squamous Cell Arsenic 14.7115504454 17687452 18922899
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 14.7120419170
MESH:D002294 Carcinoma, Squamous Cell Curcumin 14.7118462866
MESH:D002294 Carcinoma, Squamous Cell Glutathione 14.7117015178
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 14.7118572023
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 14.7111212258
MESH:D002295 Carcinoma, Transitional Cell Arsenic 7.5218640142
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 7.5217572228
MESH:D006332 Cardiomegaly Quercetin 5.4019794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.4018670907 16120746 18850075
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.6115710769 19225199
MESH:D002318 Cardiovascular Diseases Arsenic 5.8615738583 17938729 19152805
MESH:D002318 Cardiovascular Diseases Genistein 5.8616332659
MESH:D002340 Carotid Artery Diseases Arsenic 3.7318022660 16973168
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.4018974383
MESH:D002386 Cataract Acetaminophen 2.1510977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 19.987505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 19.9820889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 19.9817174075 7505956 21159647 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 19.9818566989
MESH:D002471 Cell Transformation, Neoplastic monomethylarsonous acid 19.9819716837
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 19.9819524636 20056578
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.594080065
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 12.7619052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 12.7616835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 12.7618291259
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 10.3419486331 9022650
MESH:D002779 Cholestasis Ethinyl Estradiol 10.3417110522 17681005 17333356 16105132 15861022 16919318 11677210
MESH:D002779 Cholestasis pirinixic acid 10.3419176532
MESH:D019457 Chromosome Breakage Sodium Selenite 4.0915894690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.7815340226 15668235 8697196 12621046 16354765
MESH:D003092 Colitis Curcumin 3.5216804969 16782535 18200517
MESH:D003103 Coloboma Curcumin 3.9318809619
MESH:D003110 Colonic Neoplasms Butyrates 11.6915936596
MESH:D003110 Colonic Neoplasms Curcumin 11.6919359593 16340194
MESH:D003110 Colonic Neoplasms Dexamethasone 11.6915824018
MESH:D003110 Colonic Neoplasms Genistein 11.6917182828
MESH:D003110 Colonic Neoplasms Quercetin 11.6917191121 17148506 19056647 19440933 15741050 11134977 16640504
MESH:D003110 Colonic Neoplasms zileuton 11.6918927292
MESH:D015179 Colorectal Neoplasms Quercetin 2.1818852136 18095365
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.4817141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.2318497527
MESH:D019465 Craniofacial Abnormalities Dexamethasone 2.3417728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.3415322242 20055451 10048152
MESH:D003456 Cryptorchidism vinclozolin 3.6914966744
MESH:D003550 Cystic Fibrosis Glutathione 3.9019747007
MESH:D003556 Cystitis Cyclophosphamide 4.3017010015 10498854 12161096 15643279 10700343 18433785 18483878 18372110 18295254 16413132 17979934 12388444 11948286 18093676 16651033 12913760 18710439 16614059 16989017 15276878
MESH:D003665 Decompression Sickness zileuton 5.5318309904
MESH:D003711 Demyelinating Diseases Tamoxifen 3.7019031437
MESH:D003866 Depressive Disorder tolcapone 3.807768276 11224284
MESH:D003865 Depressive Disorder, Major tolcapone 4.3210440460
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 4.922524372 18759878 11298694 8156756 8970840 12868966 14531868 11906362
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 4.9212438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.0718249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 2.872952479 3621924
MESH:D003920 Diabetes Mellitus rosiglitazone 7.4917446233
MESH:D003920 Diabetes Mellitus Sodium Selenite 7.4916285004
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 6.8011751995 10990075 15331540
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 6.8019496084
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 2.9718772604
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 11.2018403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 11.2020387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 11.2016647724
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 11.2012642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 11.2017107852
MESH:D003928 Diabetic Nephropathies Curcumin 11.6818204486
MESH:D003928 Diabetic Nephropathies Estradiol 11.6819279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 11.6819279558
MESH:D003967 Diarrhea Dexamethasone 3.077237001
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 23.839022650 11289319 16192314 6482804 9653073 18648102 6679447 18289764 9328219 18692083 7440962 1440618 8291058
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 23.8319420014 16081117 19370779 11529661 17562736 16781746 10774834 14725611 16393943 11834606 16485898 12705907 2444490 11461765 19923254 14550746 15619225 18071297 10663392 14986274 19164858 16227642 16109766 11287661 18713872 10915739 12594235 17522070 12153990 19085960 12392966 12540782 11739529 16177239 11743745 15968718 11421492 19416960 19739265 12958197 17906064
MESH:D056486 Drug-Induced Liver Injury Amiodarone 23.8315265979 18218290
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 23.8315027814 21278145 6623471 3732212 10092053 9327722 6884620 15968718 15998439 7440962 11566570 17522070 2869522 10915739 7179309 7120509 19336974 3786805 16177239 4309450 19085960 16227642
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 23.8319107877
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 23.8315131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 23.8320420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 23.8312963478
MESH:D056486 Drug-Induced Liver Injury tolcapone 23.8319783845 16604736
MESH:D056486 Drug-Induced Liver Injury zileuton 23.8317944539
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.4119426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.2411462148
MESH:D004381 Duodenal Ulcer Curcumin 3.4117351913
MESH:D004409 Dyskinesia, Drug-Induced tolcapone 4.7111455177
MESH:D050171 Dyslipidemias Dietary Fats 2.9418367378
MESH:D004417 Dyspnea Chlorine 8.3920016425
MESH:D004417 Dyspnea Diazinon 8.3916487989
MESH:D004421 Dystonia Phenobarbital 3.371851702
MESH:D004485 Eczema Dexamethasone 3.8112438553
MESH:D004487 Edema Dexamethasone 19.2519703484
MESH:D004487 Edema Mustard Gas 19.259260866 11428647 11402378 11428631
MESH:D004487 Edema pirinixic acid 19.2512083418
MESH:D004487 Edema rosiglitazone 19.2512083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 19.2512711302 11000095
MESH:D004487 Edema zileuton 19.2511698051 8273558 9831321 7990266 19703484 17118201 7812673
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.2115322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 6.8112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 6.8119031437
MESH:D004714 Endometrial Hyperplasia Genistein 3.9116402032
MESH:D016889 Endometrial Neoplasms Estradiol 9.7019148513 18566989 11473722
MESH:D016889 Endometrial Neoplasms Genistein 9.7011473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 9.7020544844 17893378 16202921 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.4310568697 9294722
MESH:D019446 Endotoxemia zileuton 4.6815328337
MESH:D004802 Eosinophilia Cyclophosphamide 15.9611006010
MESH:D004802 Eosinophilia Leukotriene E4 15.9615696079
MESH:D004802 Eosinophilia pranlukast 15.9611514498
MESH:D004802 Eosinophilia zileuton 15.9610764316 8621850
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.453659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.193922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.5020417680
MESH:D004832 Epilepsy, Absence Phenobarbital 2.976401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.597750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.343659116
MESH:D004890 Erythema Mustard Gas 4.489357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.4216302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 8.443581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 8.4420426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 8.4416530937
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 8.4415150132 15264214 16704527 15547733 15623463 15878914 16510608 15547721 16805852
MESH:D054908 Extensively Drug-Resistant Tuberculosis tolcapone 5.2519578428
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.4911564622
MESH:D005218 Fat Necrosis Thioacetamide 5.0316456712
MESH:D005234 Fatty Liver Amiodarone 37.8214986274
MESH:D005234 Fatty Liver Carbon Tetrachloride 37.8216239168 15959796 61145 12631006 16045604 17595544 19224547 12795759
MESH:D005234 Fatty Liver Curcumin 37.8219297423
MESH:D005234 Fatty Liver Dietary Fats 37.8217967931 19551842 19004024 18296743
MESH:D005234 Fatty Liver Diethylnitrosamine 37.8220387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 37.8215345470
MESH:D005234 Fatty Liver pirinixic acid 37.8220131406 19236843
MESH:D005234 Fatty Liver rosiglitazone 37.8219196556
MESH:D005234 Fatty Liver Tamoxifen 37.8214986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.7916709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.8011858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.336705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 3.8514745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.5019069698
MESH:D005355 Fibrosis Carbon Tetrachloride 20.7918705752
MESH:D005355 Fibrosis Curcumin 20.7918705752
MESH:D005355 Fibrosis Dietary Fats 20.7918296743
MESH:D005355 Fibrosis Quercetin 20.7919474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 20.7920067830
MESH:D005534 Foot Diseases Arsenic 4.876392382
MESH:D005596 Fractures, Closed zileuton 5.1719544365
MESH:D005739 Gas Poisoning Chlorine 4.3220016425
MESH:D005756 Gastritis Acetaminophen 2.9916983495
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.0318462866
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.2516973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.6116417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.0016452187
MESH:D005909 Glioblastoma Curcumin 9.2517596214
MESH:D005909 Glioblastoma Genistein 9.2516598420
MESH:D005909 Glioblastoma Quercetin 9.2519804834
MESH:D005910 Glioma Quercetin 2.7417643826
MESH:D018316 Gliosarcoma Cyclophosphamide 4.8311389073
MESH:D005911 Gliosis Paraquat 4.4711124998
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.417505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.9010696789
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.3716376943 15172196 11014644
MESH:D006258 Head and Neck Neoplasms Curcumin 3.1718462866 18829502
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 5.1020471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.1011294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.0920558911
MESH:D006467 Hemophilia A Cyclophosphamide 4.6211918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.7211000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 3.9618665440 17276928 15929193
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 4.8414986274
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 22.566705139
MESH:D006505 Hepatitis Caffeine 22.5611394713
MESH:D006505 Hepatitis Carbon Tetrachloride 22.5619110552 19900420
MESH:D006505 Hepatitis Diazinon 22.5616487989
MESH:D006505 Hepatitis Thioacetamide 22.5616456712
MESH:D006529 Hepatomegaly Amiodarone 20.2015265979
MESH:D006529 Hepatomegaly Phenobarbital 20.2016109766
MESH:D006529 Hepatomegaly pirinixic acid 20.2018467677 19772884 19176532 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 20.2012621046 16120746 15340226
MESH:D006529 Hepatomegaly zileuton 20.208661344
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.3817701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.797520565
MESH:D006558 Herpes Genitalis Estradiol 4.3415709030
MESH:D006689 Hodgkin Disease Cyclophosphamide 5.7217606976 16135485
MESH:D006689 Hodgkin Disease sodium arsenite 5.7212676792
MESH:D019584 Hot Flashes Estradiol 3.0717088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.358697196 16354765 15340226 16959395 18606429
MESH:D006930 Hyperalgesia Acetaminophen 6.0716870215
MESH:D006930 Hyperalgesia rosiglitazone 6.0712083418
MESH:D017588 Hyperandrogenism Flutamide 4.7715356085
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.8516899240
MESH:D006937 Hypercholesterolemia Amiodarone 11.828137927 9751232
MESH:D006937 Hypercholesterolemia Curcumin 11.8218704882
MESH:D006937 Hypercholesterolemia Dietary Fats 11.8221332399
MESH:D006943 Hyperglycemia pirinixic acid 7.2620558911
MESH:D006943 Hyperglycemia Quercetin 7.2611834736 18262572
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 3.8617050553
MESH:D006949 Hyperlipidemias Dietary Fats 2.9921332399
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.2815034207
MESH:D006973 Hypertension Arsenic 9.8116076760 11953799 9931084
MESH:D006973 Hypertension Dexamethasone 9.8117042910
MESH:D006973 Hypertension Quercetin 9.8118356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 9.8118850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.4315338365
MESH:D006976 Hypertension, Pulmonary zileuton 4.1614726295
MESH:D006987 Hypesthesia Arsenic 4.8716093927
MESH:D007021 Hypospadias Ethinyl Estradiol 3.1516569931 16945680
MESH:D007037 Hypothyroidism Amiodarone 3.8517991464 18020914
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 4.7518306037
MESH:D007154 Immune System Diseases Cyclophosphamide 4.6416076520
MESH:D020244 Infarction, Middle Cerebral Artery zileuton 4.9719309543
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.8312013081
MESH:D007248 Infertility, Male Cyclophosphamide 24.447193160 16517039
MESH:D007248 Infertility, Male Diazinon 24.4416466525 12948887
MESH:D007248 Infertility, Male Ethinyl Estradiol 24.4417937319
MESH:D007248 Infertility, Male Methoxychlor 24.4411955947 16467254
MESH:D007248 Infertility, Male Paraquat 24.444850670
MESH:D007248 Infertility, Male sodium arsenite 24.4412646999 15346721
MESH:D007248 Infertility, Male vinclozolin 24.4416467254
MESH:D007249 Inflammation Curcumin 32.8417151092 16956363 18403477
MESH:D007249 Inflammation Dexamethasone 32.8411099482 8960868
MESH:D007249 Inflammation Dietary Fats 32.8420412841
MESH:D007249 Inflammation Diethylnitrosamine 32.8418785209
MESH:D007249 Inflammation Mustard Gas 32.8411428620 16001271 9260866 11428647 17524151 11402378 8975870 9357497 11428631
MESH:D007249 Inflammation pranlukast 32.8419129732
MESH:D007249 Inflammation rosiglitazone 32.8412083418
MESH:D007249 Inflammation Tamoxifen 32.8419457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 32.8412878042 12200463
MESH:D007249 Inflammation Tobacco Smoke Pollution 32.8418590791
MESH:D007249 Inflammation zileuton 32.8418295198 18309904 7812673 18059327 17118201 8960868 8621850 9831321
MESH:D015212 Inflammatory Bowel Diseases Curcumin 8.8418200517 18596194
MESH:D015212 Inflammatory Bowel Diseases Leukotriene B4 8.8411006272
MESH:D015212 Inflammatory Bowel Diseases zileuton 8.8415339030
MESH:D007251 Influenza, Human Quercetin 3.8216624496
MESH:D007333 Insulin Resistance bisphenol A 22.7716393666
MESH:D007333 Insulin Resistance Dietary Fats 22.7711836018 18457598
MESH:D007333 Insulin Resistance Estradiol 22.7716393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 22.7716306350
MESH:D007333 Insulin Resistance rosiglitazone 22.7716306350
MESH:D007333 Insulin Resistance Sodium Selenite 22.7714714311
MESH:D007410 Intestinal Diseases pranlukast 5.2718236018
MESH:D007414 Intestinal Neoplasms Curcumin 3.6210783313
MESH:D007511 Ischemia pranlukast 5.5219129732
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.339022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.7216580747
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 4.7518306037
MESH:D007627 Keloid Quercetin 4.2917086741
MESH:D007642 Keratosis Arsenic 4.3116930632 12749816
MESH:D007674 Kidney Diseases Acetaminophen 10.9012587719 15629191
MESH:D007674 Kidney Diseases Estradiol 10.9015618244
MESH:D007674 Kidney Diseases Quercetin 10.9016962696
MESH:D007674 Kidney Diseases sodium arsenite 10.9020008137
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 9.176582329
MESH:D007680 Kidney Neoplasms Estradiol 9.1715610895
MESH:D007680 Kidney Neoplasms Tamoxifen 9.1718625569
MESH:D007889 Leiomyoma Curcumin 3.9418555241
MESH:D007938 Leukemia Curcumin 11.8418462866
MESH:D007938 Leukemia Cyclophosphamide 11.8410602166
MESH:D007938 Leukemia Genistein 11.8418980019 17468513
MESH:D007938 Leukemia Quercetin 11.8417468513
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.1617802794 17296974 18172266 17658394 18587576 17008537
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 3.5916106398
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 7.3710373061
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive zileuton 7.3719503090 19823023
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.0817339181
MESH:D015458 Leukemia, T-Cell Curcumin 4.1116106398
MESH:D007970 Leukopenia Cyclophosphamide 4.2911830472 10052129
MESH:D007984 Leydig Cell Tumor vinclozolin 4.0516417039
MESH:D008064 Lipidoses Amiodarone 6.2215342952 17567588
MESH:D008064 Lipidoses Tamoxifen 6.2215342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 12.3111408273 16239168 16943688 17174718 16221502 17334410 21278145 17157831 11903743
MESH:D008103 Liver Cirrhosis Dietary Fats 12.3118296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 12.3118665156 18407596 20032147 19638242 18522880
MESH:D008103 Liver Cirrhosis Phenobarbital 12.3121047994
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.749327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental 2-(4-(quinolin-2-yl-methoxy)phenyl)-2-cyclopentylacetic acid 20.2112958196 16033810
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 20.2118277467 18205269 18395914 12741479 18006644 16097048 18472094 14716833 14512876 18251166 15931870 15876570 16248980 16033810 18210741 18420326 17922224 15818738 17698563 12609069 16638106 18317297 15370692 18395095 16015684 15362042 12445418 17640975 12632514 12667390 18054572 13678700 17805973 16192424 15338365 17900296 18412020 15123356 14748882 18187930 15673190 18418968 16136751 18279442 17761835 15057751 12666154 17525996 14716496 16027843 17869086 17944888 18472332 17721639 15730626 12445421 17481882 16011737 15925388 12586293 18481824 18156304 14620537 18705752 17565644 12632512 12649538 17631135 12389079 15052691 17823541 14724832 18166357 11481614 17708605 17714472 12546737 16116963 17557913 15959796 12898905 18339082 18376398 17766677 20821823 18429990 15996030 17976157 15893842 15650968 10355542 18263696 12958196
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 20.2118006644 17355460 18705752
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 20.2116718785
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 20.2114716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 20.2117823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 20.2115474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 20.2112741479
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 20.2117347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 20.2118564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 20.2112878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 20.2112175628 17292413 18263696 18458672 15288473 18380797 16489207 17629604 16097051 11172339 12891558 16126171 12557150 18295389 18615449 14739098 18395095 12679928 17127702 15316131 15465738 18031379 17355460 15474484 15075984 11682029 16511523 15716488 17050028 18032466 18606216 15078482 16098781 15095483 12085344 16248980 16343077 15158331 15362042 11481614 15334695 10677585 18416461 12531686 15288472
MESH:D008107 Liver Diseases Acetaminophen 15.7316611625 19784758 11587558 19014921 16610002 19460945 12587719 12969438
MESH:D008107 Liver Diseases Arsenic 15.7311134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 15.7316246199 16964402 17285989 15720792 15830285
MESH:D008107 Liver Diseases Curcumin 15.7316956363
MESH:D008107 Liver Diseases Diethylnitrosamine 15.7317034775
MESH:D008107 Liver Diseases Phenobarbital 15.7319363144
MESH:D008107 Liver Diseases Thioacetamide 15.7318374380 15158337 16337175
MESH:D017093 Liver Failure Carbon Tetrachloride 3.5015123358
MESH:D017114 Liver Failure, Acute Acetaminophen 12.8116871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 12.8116899240 14706259
MESH:D017114 Liver Failure, Acute Thioacetamide 12.8115633222 17276928 12479984 15313186
MESH:D008113 Liver Neoplasms Arsenic 31.1116368122
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 31.1121137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 31.1119294768
MESH:D008113 Liver Neoplasms dicyclanil 31.1120118626
MESH:D008113 Liver Neoplasms Diethylnitrosamine 31.1120137499 21071580 20452335 9163691 15175105 19090486 19638242 16942905 19254457 19256749 18977376 2862719 19499222 20492335 21047994 20583210 19426721 20118626 21278145 19073162 20101389 10737359 18644402 19833225 12112319 2422723 18648771 19551842 19690152 19996281 19812893 19850985 18754104 20405173 12771043 19255062 21167192 20501860 15885732 19642983 20434301 19427195 19294768 18978307
MESH:D008113 Liver Neoplasms Phenobarbital 31.1119812893 15975961 8742319 21047994 19482888 19073162
MESH:D008113 Liver Neoplasms pirinixic acid 31.1120007298 15890375 16377806
MESH:D008113 Liver Neoplasms Quercetin 31.1118980244
MESH:D008113 Liver Neoplasms sodium arsenite 31.1115276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 31.1116684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 31.1116984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 21.25598648 3712494 1399818 6587162
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 21.2512014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 21.2521159647 16267830 18164116 18775883 18282651 19009564 19519916 18079962 19004024 17942915 18093689 3124819 17854601 18544905 19126423 19539802 18308698 9362446 18253720 17174075 16842330 2563599
MESH:D008114 Liver Neoplasms, Experimental kojic acid 21.2518544905
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 21.251399818 6150874 17172636 18308698 2563599
MESH:D008114 Liver Neoplasms, Experimental Quercetin 21.2519519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 21.2512151625
MESH:D008133 Long QT Syndrome Amiodarone 3.0517391786 15350150 11989578
MESH:D008171 Lung Diseases Amiodarone 13.6312587719
MESH:D008171 Lung Diseases Mustard Gas 13.6318161513 18702808
MESH:D008171 Lung Diseases Ozone 13.6319066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 13.6319095001
MESH:D017563 Lung Diseases, Interstitial Amiodarone 3.7918516814
MESH:D055370 Lung Injury Ozone 3.2020417186
MESH:D008175 Lung Neoplasms Arsenic 19.8519168569 17306315 17976673
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 19.8518816296 17053015 20464547 20869020 18569708 20135361 6695378 18520028 20064080
MESH:D008175 Lung Neoplasms Curcumin 19.8516243823 19359593 18462866
MESH:D008175 Lung Neoplasms Dexamethasone 19.8515824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 19.8520512841 20970405 21163286 6695378
MESH:D008175 Lung Neoplasms Mustard Gas 19.853148597 8781369
MESH:D008175 Lung Neoplasms Ozone 19.857614698 8597069
MESH:D008175 Lung Neoplasms Quercetin 19.8516280456
MESH:D008175 Lung Neoplasms sodium arsenite 19.8516712894 15276417 17306315 19931552 17077188
MESH:D008175 Lung Neoplasms Tamoxifen 19.8518625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 19.8519555203 11884234
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 19.8511091918 12111688 16288123 3440675
MESH:D008223 Lymphoma Curcumin 6.2418462866
MESH:D008223 Lymphoma Cyclophosphamide 6.2412854902
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 8.3016675587
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 8.3014737004
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 3.6111911406
MESH:D016399 Lymphoma, T-Cell Curcumin 4.0316173963
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.0919428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 10.4617203775 11807958 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental Genistein 10.4614578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 10.4616827153
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 10.4614580682 16827153 11731420 19196723 19196722
MESH:D020149 Manganese Poisoning Estradiol 10.3519453300
MESH:D020149 Manganese Poisoning Tamoxifen 10.3519453300
MESH:D008545 Melanoma Curcumin 4.1917885582 18462866
MESH:D008545 Melanoma sodium arsenite 4.1916487513 19082730
MESH:D008545 Melanoma Tamoxifen 4.1919393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.5015990972
MESH:D008546 Melanoma, Experimental Acetaminophen 8.6319513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 8.6316388313
MESH:D008569 Memory Disorders Curcumin 3.5117263510
MESH:D024821 Metabolic Syndrome X rosiglitazone 3.8117261469
MESH:D008679 Metaplasia Ozone 4.4110496685
MESH:D009041 Motion Sickness Dextroamphetamine 4.831613127
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 7.0116381670
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 7.0115006635
MESH:D009101 Multiple Myeloma Curcumin 5.9019372569
MESH:D009101 Multiple Myeloma Dexamethasone 5.9015744524 15867202 16118317
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.2417962980
MESH:D009135 Muscular Diseases pirinixic acid 2.8516239165
MESH:D009181 Mycoses Amiodarone 4.2117974566 12754197
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 3.129809623
MESH:D009203 Myocardial Infarction Genistein 7.5217141266
MESH:D009203 Myocardial Infarction pirinixic acid 7.5219151258
MESH:D009203 Myocardial Infarction Quercetin 7.5219595682
MESH:D017202 Myocardial Ischemia Arsenic 7.1615371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.1612213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 15.8916810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 15.8917141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 15.8916411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 15.8919207477
MESH:D009205 Myocarditis pranlukast 5.8211514498
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.8017484760
MESH:D009298 Nasal Polyps zileuton 5.5310665187
MESH:D009361 Neoplasm Invasiveness Curcumin 3.7318495463
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 7.543581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 7.543581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 7.5419393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.2519410462
MESH:D009369 Neoplasms Benzo(a)pyrene 11.6411141357
MESH:D009369 Neoplasms Cyclophosphamide 11.6418854779
MESH:D009369 Neoplasms pirinixic acid 11.6417405874
MESH:D009369 Neoplasms Quercetin 11.6415185748
MESH:D009369 Neoplasms sodium arsenite 11.6411559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.0120056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 8.5512497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 8.5519189210 19200415 19196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.0617289903
MESH:D009410 Nerve Degeneration Paraquat 3.1816893418
MESH:D009421 Nervous System Malformations bisphenol A 18.1716427766 11399458
MESH:D009421 Nervous System Malformations Estradiol 18.1716427766 11399458
MESH:D009421 Nervous System Malformations Genistein 18.1716427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 18.1714600291
MESH:D009423 Nervous System Neoplasms Curcumin 4.9418462866
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 9.426679447
MESH:D009436 Neural Tube Defects Arsenic 9.4216620997
MESH:D009436 Neural Tube Defects sodium arsenite 9.4212854658
MESH:D009447 Neuroblastoma Cyclophosphamide 3.2516115947 8761367 15176712
MESH:D019636 Neurodegenerative Diseases Acetaminophen 6.3118514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 6.3120387270
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 4.2112837982 8761367
MESH:D020078 Neurogenic Inflammation Arsenic 8.6017056641
MESH:D020078 Neurogenic Inflammation Quercetin 8.6017929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.4220387270
MESH:D009503 Neutropenia Cyclophosphamide 12.148291058
MESH:D009503 Neutropenia Leukotriene B4 12.148305713
MESH:D009503 Neutropenia Mustard Gas 12.1416761898 7688884
MESH:D009765 Obesity Curcumin 6.1019297423
MESH:D009765 Obesity Dietary Fats 6.1017217161 18457598 21332399 20132043 18674790 16723640 20518802 19632207 11836018
MESH:D009765 Obesity pirinixic acid 6.1020558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 2.834026338 6482804
MESH:D009845 Oligospermia Cyclophosphamide 4.0416517039
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.333988306
MESH:D010018 Osteomalacia Phenobarbital 3.6917016548
MESH:D010024 Osteoporosis Curcumin 5.8518719352
MESH:D010024 Osteoporosis Genistein 5.8519401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 8.0516169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 8.0519495926
MESH:D010049 Ovarian Diseases bisphenol A 4.3111985600
MESH:D010051 Ovarian Neoplasms Arsenic 18.7217306315
MESH:D010051 Ovarian Neoplasms CD 437 18.7217474084
MESH:D010051 Ovarian Neoplasms Curcumin 18.7219020741 18462866
MESH:D010051 Ovarian Neoplasms Estradiol 18.7219401270
MESH:D010051 Ovarian Neoplasms Genistein 18.7219005980
MESH:D010051 Ovarian Neoplasms Quercetin 18.7219005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 18.7215276417 17306315
MESH:D010146 Pain Acetaminophen 8.2716870215
MESH:D010146 Pain Cyclophosphamide 8.2712161096 18093676
MESH:D010146 Pain zileuton 8.2715935457
MESH:D010190 Pancreatic Neoplasms Curcumin 13.1019401701 19196508 17440100
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 13.1011332152
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 13.1016540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 13.1016965848
MESH:D010190 Pancreatic Neoplasms Quercetin 13.1016965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.0611578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 2.837296757
MESH:D010300 Parkinson Disease Paraquat 4.7815451049 11124998 12911755 11181820 11445065 15824117 16510128 16140633
MESH:D010300 Parkinson Disease tolcapone 4.789333106 20216409 11432539 9708959 17089403 9305320 11793426 8635184 19783845 20334432 8739811 16758261 7566641 18328768 9754991 1977408 11746615 9591521 11586115 19578428 10651109
MESH:D010302 Parkinson Disease, Secondary Paraquat 3.7716190885
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.5612520081
MESH:D010523 Peripheral Nervous System Diseases Arsenic 3.5416093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.3116905509 6392382 15371236
MESH:D010538 Peritonitis Ozone 8.3616369182
MESH:D010538 Peritonitis zileuton 8.3617371808
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 3.786228378
MESH:D011014 Pneumonia Ozone 8.8218007984 18381685 18929643
MESH:D011014 Pneumonia Paraquat 8.8212504350
MESH:D011041 Poisoning Diazinon 6.9517603234
MESH:D011041 Poisoning Mustard Gas 6.9515727166
MESH:D011085 Polycystic Ovary Syndrome Flutamide 4.3915356085
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.9118163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 12.022563599
MESH:D011230 Precancerous Conditions Phenobarbital 12.022563599
MESH:D011230 Precancerous Conditions Quercetin 12.0219056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 6.4021297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 6.4021297632
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 12.3510548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 12.3511896295 11399792 11118676 11222880
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 12.3518042343 18220299 19015723
MESH:D011469 Prostatic Diseases vinclozolin 4.2518220299
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 8.5120887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 8.5120887781
MESH:D011471 Prostatic Neoplasms Arsenic 4.3416140617
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 4.3417292933
MESH:D011471 Prostatic Neoplasms bisphenol A 4.3416740699
MESH:D011471 Prostatic Neoplasms Curcumin 4.3411398177 12497104 15129424 18226269 18156803 10851300 18769126
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 4.3417136230
MESH:D011471 Prostatic Neoplasms Estradiol 4.3416740699
MESH:D011471 Prostatic Neoplasms Flutamide 4.343169114
MESH:D011471 Prostatic Neoplasms Genistein 4.3416925846 15256057 15378649
MESH:D011471 Prostatic Neoplasms Quercetin 4.3417292933 14715546
MESH:D011471 Prostatic Neoplasms sodium arsenite 4.3416039940
MESH:D011471 Prostatic Neoplasms Sodium Selenite 4.3418760546
MESH:D011471 Prostatic Neoplasms Tamoxifen 4.3415067354
MESH:D011472 Prostatitis vinclozolin 4.2518629315
MESH:D011507 Proteinuria 2-(4-(quinolin-2-yl-methoxy)phenyl)-2-cyclopentylacetic acid 8.0912649539
MESH:D011507 Proteinuria Arsenic 8.0921343184
MESH:D011537 Pruritus Ethinyl Estradiol 12.3915861022 16919318
MESH:D011537 Pruritus Mustard Gas 12.3918058305
MESH:D011537 Pruritus zileuton 12.3919657356 17827870
MESH:D019310 Pseudolymphoma Phenobarbital 3.8012752131
MESH:D011565 Psoriasis Leukotriene B4 4.0511006272
MESH:D011629 Puberty, Precocious bisphenol A 4.1110548101
MESH:D011654 Pulmonary Edema zileuton 4.7418309904
MESH:D011656 Pulmonary Emphysema Curcumin 3.9319168576
MESH:D011658 Pulmonary Fibrosis Amiodarone 10.6211597910 12490602 12832656
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 10.6216636934
MESH:D011658 Pulmonary Fibrosis Mustard Gas 10.6217266442 17720292 17894541 17620002 10334151
MESH:D011658 Pulmonary Fibrosis Paraquat 10.6216324872 17997886
MESH:D015427 Reperfusion Injury Leukotriene C4 9.0712967936
MESH:D015427 Reperfusion Injury pirinixic acid 9.0719058328
MESH:D015427 Reperfusion Injury zileuton 9.079865762 15266012
MESH:D012120 Respiration Disorders Chlorine 4.5218579056
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 11.6418379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 11.6418379247 11700416
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 11.6411700416
MESH:D012135 Respiratory Sounds Paraquat 7.7511874814
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 7.7518410779
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.1918990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 7.163692021
MESH:D012162 Retinal Degeneration Paraquat 7.1616458197
MESH:D012220 Rhinitis pranlukast 7.8720332717
MESH:D012220 Rhinitis zileuton 7.8720332717
MESH:D012509 Sarcoma Curcumin 3.5218462866
MESH:D012554 Schistosomiasis japonica Quercetin 4.8516862918
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 4.1916636934
MESH:D012640 Seizures Phenobarbital 2.244039156 3137016 11442880 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.146407741
MESH:D018805 Sepsis Curcumin 3.5118389075
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.4018724381
MESH:D012852 Sinusitis zileuton 4.8410665187
MESH:D012871 Skin Diseases Arsenic 6.7517938729 16759981 19834688 16702368 6392382 16353154 15952646 17548696 17050553 18709164 17453740
MESH:D012871 Skin Diseases monomethylarsonous acid 6.7517431481
MESH:D012871 Skin Diseases Mustard Gas 6.7512880345 16961503 15451306
MESH:D012878 Skin Neoplasms Arsenic 13.9817050553 17976673 17029826 16251483 19538983 15504454
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 13.9819755658 10029692
MESH:D012878 Skin Neoplasms sodium arsenite 13.9818572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 13.9816192470
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 13.9818590791
MESH:D020181 Sleep Apnea, Obstructive BAY u9773 11.2419118273
MESH:D020181 Sleep Apnea, Obstructive zileuton 11.2419118273
MESH:D012893 Sleep Disorders Caffeine 4.6419395429
MESH:D007319 Sleep Initiation and Maintenance Disorders Caffeine 4.4217225163
MESH:D013088 Spermatocele Ethinyl Estradiol 9.2616709447
MESH:D013088 Spermatocele Tamoxifen 9.2616709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 4.8316517039
MESH:D013119 Spinal Cord Injuries Tamoxifen 9.0819457130
MESH:D013119 Spinal Cord Injuries zileuton 9.0818059327
MESH:D016135 Spinal Dysraphism sodium arsenite 3.2612854658
MESH:D013272 Stomach Diseases Dexamethasone 3.6515472012
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.882093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.8818456281
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 2.8812958204 17575124
MESH:D013276 Stomach Ulcer Amiodarone 12.3518087811
MESH:D013276 Stomach Ulcer Curcumin 12.3516631530 19188055
MESH:D013276 Stomach Ulcer Dexamethasone 12.3515138204
MESH:D013276 Stomach Ulcer Leukotriene D4 12.351323529
MESH:D019966 Substance-Related Disorders bisphenol A 3.3116684133 16045194
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 4.3812837982
MESH:D013610 Tachycardia Amiodarone 3.6411238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 3.5519225199
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.9911994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.5715669648
MESH:D013959 Thyroid Diseases Amiodarone 9.7519731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 9.7512697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 12.781399818 3712494 7505956 6582329 6587162
MESH:D013964 Thyroid Neoplasms Butyrates 12.7817967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 12.787505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 12.781399818
MESH:D013971 Thyrotoxicosis Amiodarone 4.2018020914 19584973
MESH:D013978 Tibial Fractures Estradiol 3.9919048282
MESH:D016171 Torsades de Pointes Amiodarone 3.5211989578 17467628
MESH:D018088 Tuberculosis, Multidrug-Resistant tolcapone 5.2519578428
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 34.578074119
MESH:D001749 Urinary Bladder Neoplasms Arsenic 34.5717976673 17306315 11144890 18640142 19322015 15987713 19429237
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 34.5717053015
MESH:D001749 Urinary Bladder Neoplasms CD 437 34.5716720286
MESH:D001749 Urinary Bladder Neoplasms Curcumin 34.5718593936
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 34.5714692829
MESH:D001749 Urinary Bladder Neoplasms monomethylarsonous acid 34.5720375083
MESH:D001749 Urinary Bladder Neoplasms Quercetin 34.5716720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 34.5716452187 17306315 11723127 16712894
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 34.578653321 16712894 17572228
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 34.5712846360
MESH:D014565 Urogenital Neoplasms Curcumin 4.5818462866
MESH:D014570 Urologic Diseases Diazinon 4.5916487989
MESH:D014581 Urticaria Acetaminophen 2.3610982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.1711813266
MESH:D014591 Uterine Diseases bisphenol A 4.3214652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.6614692618
MESH:D014605 Uveitis Dexamethasone 4.131336536
MESH:D014652 Vascular Diseases Arsenic 9.6017056641
MESH:D014652 Vascular Diseases sodium arsenite 9.6017056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.9012125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.9314671159 15869587
MESH:D014820 Vitiligo tolcapone 4.5510573327
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.5615886252
MESH:D015430 Weight Gain Dietary Fats 3.1616723640
Pathway ID Pathway Name
REACT:13433 Biological oxidations
KEGG:00982 Drug metabolism - cytochrome P450
KEGG:00480 Glutathione metabolism
KEGG:00980 Metabolism of xenobiotics by cytochrome P450
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB00143 - BSS Plus Dietary supplement;Micronutrient
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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