AutismKB 2.0

Annotation Detail for MIF


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Basic Information Top
Gene Symbol:MIF ( GIF,GLIF,MMIF )
Gene Full Name: macrophage migration inhibitory factor (glycosylation-inhibiting factor)
Band: 22q11.23
Quick LinksEntrez ID:4282; OMIM: 153620; Uniprot ID:MIF_HUMAN; ENSEMBL ID: ENSG00000133460; HGNC ID: 7097
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00360Phenylalanine metabolism
hsa00350Tyrosine metabolism
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1774Necrotizing enterocolitis
1800Lupus vulgaris
1807Autoimmune disease
1818Systemic scleroderma
1831Prostate cancer
1856Obesity
1859Ovarian cancer
1860Brain tumor
1901Endometriosis
1916Pervasive development disorder
1932Pancreatitis
1944Breast cancer
1962Respiratory distress syndrome
1841Stomach cancer
2029Tuberculosis
2038Gastritis
2044Pre-Eclampsia
2053Colon cancer
1925Pemphigoid, Bullous
2066Lung cancer
2068Skin disease
1823Infertility, Male
2083IGA glomerulonephritis
2094Ulcerative colitis
2099Hepatitis B
2111Systemic infection
2146Lupus erythematosus
2154Adenoma
2157Scleroderma
2171Celiac disease
2231Arthritis
2241Infertility
1882Malaria
2256Aortic aneurysm
Desease Name
rheumatoid arthritis
juvenile arthritis
juvenile idiopathic arthritis
polyarthritis
CARDIOVASCULAR
biliary atresia
heart disease, ischemic
pancreatitis, acute
ulcerative colitis
PHARMACOGENOMIC
Asthma
inflammatory response in coronary bypass
allogeneic stem cell transplantation
malaria
alopecia areata
IMMUNE
cystic fibrosis Peudomonas aeruginosa
sepsis
atopy
METABOLIC
lupus erythematosus
obesity
psoriasis
Crohn's disease
arthritis, juvenile
Crohn's disease ulcerative colitis
INFECTION
sarcoidosis
No data
Desease Name
Rheumatoid arthritis, systemic juvenile, susceptibility to
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of MIF mRNAdecreases expression 18648102
C412373 AG 1879 AG 1879 inhibits the reaction [MIF protein results in increased expression of MMP2 protein]decreases reaction|increases expression 16872482
C412373 AG 1879 AG 1879 inhibits the reaction [MIF protein results in increased phosphorylation of JUN protein]decreases reaction|increases phosphorylation 16872482
C412373 AG 1879 AG 1879 inhibits the reaction [MIF protein results in increased phosphorylation of MAPK8 protein]decreases reaction|increases phosphorylation 16872482
C412373 AG 1879 AG 1879 inhibits the reaction [MIF protein results in increased phosphorylation of PRKCD protein]decreases reaction|increases phosphorylation 16872482
D013196 Dihydrotestosterone Dihydrotestosterone results in increased expression of MIF proteinincreases expression 16751997
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MIF mRNAaffects expression 16483693
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [MIF protein results in increased phosphorylation of JUN protein]decreases reaction|increases phosphorylation 16872482
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [MIF protein results in increased phosphorylation of PRKCD protein]decreases reaction|increases phosphorylation 16872482
C006632 arsenic trioxide arsenic trioxide results in decreased expression of MIF proteindecreases expression 19364129
C002791 bismuth tripotassium dicitrate bismuth tripotassium dicitrate results in increased expression of MIF mRNAincreases expression 15912405
C032036 bromobenzene bromobenzene metabolite binds to MIF proteinaffects binding 17305373
D002392 Catechin Catechin results in decreased expression of MIF mRNAdecreases expression 15465739
C012843 cinnamic aldehyde cinnamic aldehyde results in increased expression of MIF mRNAincreases expression 11244134
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of MIF mRNAaffects cotreatment|affects expression 17602206
D003474 Curcumin Curcumin results in decreased expression of MIFdecreases expression 18462866
D004041 Dietary Fats Dietary Fats results in increased expression of MIF mRNAincreases expression 18457598
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of MIF mRNAaffects cotreatment|affects expression 17602206
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MIF mRNAaffects cotreatment|decreases expression 18544905
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid] results in increased expression of MIF mRNAaffects cotreatment|increases expression 18544905
D004139 Dinitrofluorobenzene Dinitrofluorobenzene results in increased expression of MIF mRNAincreases expression 11244134
D004281 Docosahexaenoic Acids Docosahexaenoic Acids results in decreased expression of MIF mRNAdecreases expression 16623957
C031818 enterotoxin B, staphylococcal MIF protein affects the susceptibility to enterotoxin B, staphylococcalaffects response to substance 9892616
D004958 Estradiol Estradiol results in increased expression of MIF mRNAincreases expression 11861973
D004958 Estradiol Tetrachlorodibenzodioxin promotes the reaction [Estradiol results in increased expression of MIF mRNA]increases expression|increases reaction 11861973
D000431 Ethanol Ethanol results in increased expression of MIF mRNAincreases expression 15353170
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of MIF mRNAaffects expression 17555576
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MIF mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of MIF mRNAincreases expression 15576828
16174780
D005419 Flavonoids Flavonoids results in increased expression of MIF mRNAincreases expression 15465739
D005492 Folic Acid Folic Acid affects the expression of MIF mRNAaffects expression 17320366
C043055 gallium arsenide gallium arsenide results in increased expression of MIF mRNAincreases expression 14560044
D006851 Hydrochloric Acid Hydrochloric Acid results in increased expression of MIF mRNAincreases expression 12853844
D006851 Hydrochloric Acid Hydrochloric Acid results in increased expression of MIF proteinincreases expression 12853844
D007657 Ketone Bodies Ketone Bodies results in decreased expression of MIF mRNAdecreases expression 15469884
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MIF mRNAaffects cotreatment|decreases expression 18544905
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid] results in increased expression of MIF mRNAaffects cotreatment|increases expression 18544905
D008070 Lipopolysaccharides methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MIF mRNA]decreases reaction|increases expression 15933225
D008070 Lipopolysaccharides MIF protein affects the susceptibility to Lipopolysaccharidesaffects response to substance 9892616
D008694 Methamphetamine Methamphetamine results in decreased expression of MIF mRNAdecreases expression 19149911
D008715 Methionine Methionine deficiency results in increased expression of MIF mRNAincreases expression 15924568
C008435 methyldithiocarbamate methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of MIF mRNA]decreases reaction|increases expression 15933225
D009151 Mustard Gas Mustard Gas results in decreased expression of MIF mRNAdecreases expression 12884408
D009151 Mustard Gas Mustard Gas results in increased expression of MIF mRNAincreases expression 18955075
D010936 Plant Extracts Plant Extracts results in increased expression of MIF mRNAincreases expression 15465739
C025299 polyphenols polyphenols results in increased expression of MIF mRNAincreases expression 15465739
D011794 Quercetin Quercetin results in increased expression of MIF mRNAincreases expression 19729006
C071924 Ro 31-8425 Ro 31-8425 inhibits the reaction [MIF protein results in increased expression of MMP2 protein]decreases reaction|increases expression 16872482
C085746 rottlerin rottlerin inhibits the reaction [MIF protein results in increased expression of MMP2 protein]decreases reaction|increases expression 16872482
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MIF mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin promotes the reaction [Estradiol results in increased expression of MIF mRNA]increases expression|increases reaction 11861973
D014212 Tretinoin Tretinoin results in increased expression of MIF mRNAincreases expression 17218384
D014303 Trinitrotoluene Trinitrotoluene affects the expression of MIF mRNAaffects expression 21346803
C025643 vinclozolin vinclozolin results in increased expression of MIF mRNAincreases expression 18629315
D015054 Zymosan MIF gene mutant form inhibits the reaction [Zymosan results in increased expression of MMP2 protein]decreases reaction|increases expression 16872482
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 11.8718926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 11.8715322242 11752688 14514962
MESH:D000014 Abnormalities, Drug-Induced Trinitrotoluene 11.877525203
MESH:D000138 Acidosis Ammonium Chloride 15.3918287403
MESH:D000138 Acidosis Ethanol 15.3911192467
MESH:D000138 Acidosis Hydrochloric Acid 15.3915920416 20872349 19262391 12771618 11574821 16144966
MESH:D000141 Acidosis, Renal Tubular Hydrochloric Acid 5.3517183249
MESH:D000142 Acidosis, Respiratory Hydrochloric Acid 5.3720597076
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5017505938
MESH:D058186 Acute Kidney Injury Folic Acid 3.9517003819 16316344 16595132
MESH:D055371 Acute Lung Injury Hydrochloric Acid 8.3419060228 15970105 19094174 19760209 16759491 11953099 11850527
MESH:D055371 Acute Lung Injury Lipopolysaccharides 8.3411850527 18653653
MESH:D000230 Adenocarcinoma arsenic trioxide 6.3011798837 19825857
MESH:D000230 Adenocarcinoma Estradiol 6.3011473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.3014692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 9.783712494
MESH:D000236 Adenoma Diethylnitrosamine 9.786695378 10737359
MESH:D000236 Adenoma Folic Acid 9.7816963246
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 8.6217620307 16434500 19052882 17162532 19061943 18056438
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.6216835633
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.8815451039 15451040
MESH:D019973 Alcohol-Related Disorders Curcumin 4.6417887948
MESH:D000505 Alopecia Tretinoin 3.2715955085
MESH:D000544 Alzheimer Disease Curcumin 6.1915590663
MESH:D000544 Alzheimer Disease Folic Acid 6.1917116317
MESH:D000544 Alzheimer Disease Plant Extracts 6.1916962711
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.7511748828
MESH:D000740 Anemia Zymosan 7.7518664788
MESH:D000743 Anemia, Hemolytic Quercetin 3.8517084956
MESH:D000853 Anophthalmos Ethanol 4.4015513904
MESH:D000860 Anoxia Hydrochloric Acid 4.8715090967
MESH:D001008 Anxiety Disorders Ethanol 7.8811141031
MESH:D001008 Anxiety Disorders vinclozolin 7.8819015723
MESH:D001161 Arteriosclerosis Dietary Fats 8.5115238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.5111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 15.3515885639
MESH:D001169 Arthritis, Experimental Plant Extracts 15.3514686799
MESH:D001169 Arthritis, Experimental Tretinoin 15.3516412693
MESH:D001169 Arthritis, Experimental Zymosan 15.3515142272 17659584 15944321 15188379 16872482
MESH:D001171 Arthritis, Juvenile Rheumatoid marker/mechanism
MESH:D001172 Arthritis, Rheumatoid marker/mechanism 16872482
MESH:D001172 Arthritis, Rheumatoid Curcumin 4.3416807698
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.3416292516
MESH:D001249 Asthma Mustard Gas 4.4810378619
MESH:D001249 Asthma Tretinoin 4.4816456186
MESH:D001260 Ataxia Telangiectasia Quercetin 4.5515336622
MESH:D050197 Atherosclerosis Curcumin 3.0618704882
MESH:D001321 Autistic Disorder marker/mechanism 18676531
MESH:D001321 Autistic Disorder Docosahexaenoic Acids 2.5918582451
MESH:D001321 Autistic Disorder Folic Acid 2.5921388746
MESH:D001321 Autistic Disorder Methionine 2.5919056591 16917939 19267885
MESH:D001327 Autoimmune Diseases Curcumin 9.4719761891
MESH:D001327 Autoimmune Diseases Quercetin 9.4719761891
MESH:D001471 Barrett Esophagus Tretinoin 3.9916935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.5811289319 1440618
MESH:D001768 Blister Mustard Gas 4.7319167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 18.8716206674
MESH:D001778 Blood Coagulation Disorders Hydrochloric Acid 18.8715920416
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 18.8712125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 18.8716206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4815746008
MESH:D002545 Brain Ischemia Curcumin 9.0616770732
MESH:D002545 Brain Ischemia Plant Extracts 9.0616041641
MESH:D001932 Brain Neoplasms Curcumin 3.5717596214
MESH:D001943 Breast Neoplasms Curcumin 4.3119250217 16243823 18593918 18462866
MESH:D001943 Breast Neoplasms Dietary Fats 4.3120435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 4.3117474063
MESH:D001943 Breast Neoplasms Estradiol 4.3117018787 19861407 18497071 14630087 17289903 17261762 12948864 16675129
MESH:D001943 Breast Neoplasms Folic Acid 4.3116777985
MESH:D001943 Breast Neoplasms Quercetin 4.3118628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 4.3120435547
MESH:D001943 Breast Neoplasms Tretinoin 4.3116873071 16443354 16166294
MESH:D016535 Bronchial Hyperreactivity Hydrochloric Acid 4.2512378975
MESH:D001986 Bronchial Spasm Hydrochloric Acid 5.0315578804
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.7315286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.5417687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.1616813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.9311589617
MESH:D002056 Burns Ethanol 4.2316374292
MESH:D002057 Burns, Chemical Plant Extracts 4.909625245
MESH:D002105 Cadmium Poisoning Quercetin 5.1116962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0316111702
MESH:D002277 Carcinoma Curcumin 7.1618593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.1616835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.7216168501
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 18.217296757 3581430
MESH:D006528 Carcinoma, Hepatocellular anthra(1,9-cd)pyrazol-6(2H)-one 18.2119418558
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 18.2116217749 14691202 11135700 15553829 15073043
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 18.2117055752 16698587 17173139 19335982 16935385 20084675 16288022 20007298 17138121 20524982 16502159 19383236 19052882 19107877 19701751 20432363 3084413 16830150 16328049 18393292 17978847 18785209 19919837 18494052 10672840 18056438 16569478 16681979 20514400 18691550 20214788 17428255 18788625 16540662 16878318 21159647 19539802 18978308 18210153 17761372 20727157 20935162 19208518 16779866 18506893 11831363 19171122 20512989 18665156 19394651 10737359 3581430 18971187 19519916 19418558 19822196 17162532 16807293 20101231
MESH:D006528 Carcinoma, Hepatocellular Estradiol 18.2116924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 18.2115289165 15763234 18788625
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 18.2118834353
MESH:D006528 Carcinoma, Hepatocellular Quercetin 18.2112508355 19519916
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 18.211917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.8218414057
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.5317234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.4319014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.467296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.7412490120
MESH:D002294 Carcinoma, Squamous Cell Curcumin 4.3618462866
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.3616051514 16096774
MESH:D006332 Cardiomegaly Ethanol 14.3219332462
MESH:D006332 Cardiomegaly Plant Extracts 14.3217645561
MESH:D006332 Cardiomegaly Quercetin 14.3219794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 14.3218670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Folic Acid 3.6516755160
MESH:D002386 Cataract Tretinoin 6.8317460283
MESH:D002386 Cataract Trinitrotoluene 6.8314694615 15817613
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 13.647505956
MESH:D002471 Cell Transformation, Neoplastic cinnamic aldehyde 13.648243401
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 13.6417174075 7505956 21159647 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 13.6418566989
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.1616129372
MESH:D002659 Child Development Disorders, Pervasive Methionine 4.1519267885
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.1219052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.1216835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 6.8019486331 9022650
MESH:D002779 Cholestasis Ethinyl Estradiol 6.8015861022 16919318 17110522 17333356 16105132 17681005 11677210
MESH:D002822 Choriocarcinoma Tretinoin 4.7216461808
MESH:D002971 Cleft Lip Ethanol 7.1015513904
MESH:D002971 Cleft Lip Folic Acid 7.1021254359
MESH:D002972 Cleft Palate Ethanol 12.5215513904
MESH:D002972 Cleft Palate Folic Acid 12.528946559 21254359
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 12.5215668235 15340226 8697196 16354765 12621046
MESH:D002972 Cleft Palate Tretinoin 12.529407595
MESH:D003092 Colitis Curcumin 8.2518200517 16804969 16782535
MESH:D003092 Colitis Tretinoin 8.2517035595
MESH:D003103 Coloboma Curcumin 4.1618809619
MESH:D003110 Colonic Neoplasms cinnamic aldehyde 7.6217510524 16343908
MESH:D003110 Colonic Neoplasms Curcumin 7.6216340194 19359593
MESH:D003110 Colonic Neoplasms polyphenols 7.6216293270
MESH:D003110 Colonic Neoplasms Quercetin 7.6219440933 16640504 19056647 17148506 11134977 17191121 15741050
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.3120501625
MESH:D015179 Colorectal Neoplasms Folic Acid 3.3117087956 17116713 17245555 16985020 16963246
MESH:D015179 Colorectal Neoplasms Quercetin 3.3118852136 18095365
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.0714669216 17141729
MESH:D000013 Congenital Abnormalities Trinitrotoluene 8.0715095906
MESH:D016510 Corneal Neovascularization Curcumin 4.4718497527
MESH:D023903 Coronary Restenosis arsenic trioxide 3.7812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 4.9410525206
MESH:D019465 Craniofacial Abnormalities Ethanol 4.9411198716 11873399 10194807 15451039 15513904 15451040 19302082
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.9410048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 4.949142499 17551590 9224671 10589399 9664655 8800419 14991402 16925845 9211117 9125849
MESH:D003456 Cryptorchidism vinclozolin 3.9314966744
MESH:D003490 Cyanosis Trinitrotoluene 4.5018551238
MESH:D003550 Cystic Fibrosis Docosahexaenoic Acids 4.3019747007
MESH:D003556 Cystitis Hydrochloric Acid 5.0320719367 12853844 19279288 12599022
MESH:D018856 Cystitis, Interstitial Hydrochloric Acid 5.3717714534
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.7015213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 6.1111298694 8156756 2524372 11906362 8970840 12868966 14531868 18759878
MESH:D017449 Dermatitis, Allergic Contact cinnamic aldehyde 6.1111042091
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.103621924 2952479
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.3819496084
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 9.2518403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 9.2520387270
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 9.2516886840
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 9.2517107852
MESH:D003928 Diabetic Nephropathies Curcumin 13.0718204486
MESH:D003928 Diabetic Nephropathies Estradiol 13.0719279558
MESH:D003928 Diabetic Nephropathies Plant Extracts 13.0719706694
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 16.4318648102 18289764 16192314 6679447 9328219 18692083 6482804 7440962 9653073 1440618 8291058 11289319 9022650
MESH:D056486 Drug-Induced Liver Injury bromobenzene 16.4310092053 12628495
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 16.4319107877
MESH:D056486 Drug-Induced Liver Injury Ethanol 16.4311566570
MESH:D056486 Drug-Induced Liver Injury polyphenols 16.4319370779
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 16.4320420201
MESH:D056486 Drug-Induced Liver Injury Trinitrotoluene 16.4318551238 21346803
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.4411462148
MESH:D004381 Duodenal Ulcer Curcumin 3.6417351913
MESH:D050171 Dyslipidemias Dietary Fats 3.1418367378
MESH:D004487 Edema Mustard Gas 13.4111428647 9260866 11402378 11428631
MESH:D004487 Edema Plant Extracts 13.4112787963
MESH:D004487 Edema Tetrachlorodibenzodioxin 13.4111000095 12711302
MESH:D004487 Edema Zymosan 13.417907874
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.4815322242 16714409 18230668
MESH:D004489 Edema, Cardiac Tretinoin 10.4818230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 2.7812538720
MESH:D016889 Endometrial Neoplasms Estradiol 10.8911473722 19148513 18566989
MESH:D016889 Endometrial Neoplasms Folic Acid 10.8917301261
MESH:D016889 Endometrial Neoplasms Tretinoin 10.8916569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.659294722 10568697
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 5.2415268973
MESH:D019446 Endotoxemia Lipopolysaccharides 3.9715821434 15328337 17637181
MESH:D004816 Epidermal Necrolysis, Toxic marker/mechanism 9372356
MESH:D004827 Epilepsy Plant Extracts 3.5019700373 19439326
MESH:D004890 Erythema Mustard Gas 4.739357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6816302075
MESH:D004935 Esophageal Diseases Hydrochloric Acid 5.3619566590
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 6.563581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.5612903497
MESH:D004938 Esophageal Neoplasms Ethanol 6.5616704527
MESH:D004941 Esophagitis Hydrochloric Acid 5.5612928072
MESH:D004942 Esophagitis, Peptic Hydrochloric Acid 5.5820516732 11346197 14621274
MESH:D017889 Exfoliation Syndrome Folic Acid 5.0616504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.7611564622
MESH:D005124 Eye Abnormalities Tretinoin 7.7616938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 31.0715073043
MESH:D005234 Fatty Liver Curcumin 31.0719297423
MESH:D005234 Fatty Liver Dietary Fats 31.0717967931 19551842 19004024 18296743
MESH:D005234 Fatty Liver Diethylnitrosamine 31.0720387270 21071580
MESH:D005234 Fatty Liver Ethanol 31.0719236843 16409862 18620774
MESH:D005234 Fatty Liver Ethinyl Estradiol 31.0715345470
MESH:D005234 Fatty Liver Plant Extracts 31.0715975614
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.2217920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.8716946407 15513904 10194807 15451040
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0411858732
MESH:D005334 Fever Lipopolysaccharides 3.649205823 11852909
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.586705139
MESH:D005355 Fibrosis Curcumin 29.0618705752
MESH:D005355 Fibrosis Dietary Fats 29.0618296743
MESH:D005355 Fibrosis Hydrochloric Acid 29.0618497604
MESH:D005355 Fibrosis Quercetin 29.0619474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 29.0620067830
MESH:D005355 Fibrosis Tretinoin 29.0617994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.8516904648
MESH:D005739 Gas Poisoning Hydrochloric Acid 5.0312378975
MESH:D005756 Gastritis Ethanol 10.1915046732
MESH:D005756 Gastritis Folic Acid 10.1917171786
MESH:D005764 Gastroesophageal Reflux Hydrochloric Acid 4.9219957777 20516732 20616304 12212954 19951613 20545468
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.2718462866
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.5016973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.8616417039
MESH:D005901 Glaucoma Folic Acid 4.6816504073
MESH:D005909 Glioblastoma Curcumin 10.3117596214
MESH:D005909 Glioblastoma Quercetin 10.3119804834
MESH:D005909 Glioblastoma Tretinoin 10.3117312396
MESH:D005910 Glioma Quercetin 2.8717643826
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.647505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1510696789
MESH:D006258 Head and Neck Neoplasms Curcumin 6.9118829502 18462866
MESH:D006258 Head and Neck Neoplasms Tretinoin 6.9116096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.7216084493
MESH:D006356 Heartburn Hydrochloric Acid 5.3619566590
MESH:D006330 Heart Defects, Congenital Folic Acid 9.8617286298 16524890
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.8610048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 9.869664655 14991402
MESH:D006333 Heart Failure Plant Extracts 3.6018097624
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.0116366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9511000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.276705139
MESH:D006505 Hepatitis Zymosan 8.2719110552
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.3315340226 12621046 16120746
MESH:D006529 Hepatomegaly Trinitrotoluene 7.3315817613
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.6217701891
MESH:D006558 Herpes Genitalis Estradiol 4.5915709030
MESH:D006561 Herpes Simplex Plant Extracts 4.2010715843
MESH:D015658 HIV Infections Plant Extracts 3.4512878215
MESH:D006679 HIV Seropositivity Folic Acid 5.0617209195
MESH:D019584 Hot Flashes Estradiol 8.8717088409
MESH:D019584 Hot Flashes Plant Extracts 8.8717454163 16566672 14716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.6115340226 18606429 8697196 16354765 16959395
MESH:D006930 Hyperalgesia Ethanol 6.8718783367
MESH:D006930 Hyperalgesia Tretinoin 6.8716870215
MESH:D006937 Hypercholesterolemia Curcumin 7.9618704882
MESH:D006937 Hypercholesterolemia Dietary Fats 7.9621332399
MESH:D006940 Hyperemia Hydrochloric Acid 5.2212646421
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.1516778211
MESH:D006943 Hyperglycemia Quercetin 3.6618262572 11834736
MESH:D020138 Hyperhomocysteinemia Catechin 13.6617292331
MESH:D020138 Hyperhomocysteinemia Folic Acid 13.6616397167 16395265 16755160 16433478 16865747
MESH:D020138 Hyperhomocysteinemia Plant Extracts 13.6616484555
MESH:D006948 Hyperkinesis Methamphetamine 5.0817658665
MESH:D006949 Hyperlipidemias Dietary Fats 8.1421332399
MESH:D006949 Hyperlipidemias Plant Extracts 8.1415268973 15975614
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.5215034207
MESH:D006973 Hypertension Quercetin 4.6318356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.6318850075 18670907
MESH:D006975 Hypertension, Portal Hydrochloric Acid 4.9316984587
MESH:D006976 Hypertension, Pulmonary Hydrochloric Acid 4.1519262391
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3916945680 16569931
MESH:D007022 Hypotension Hydrochloric Acid 4.3611574821
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 9.6117937319
MESH:D007248 Infertility, Male Trinitrotoluene 9.6112150543
MESH:D007248 Infertility, Male vinclozolin 9.6116467254
MESH:D007249 Inflammation Curcumin 36.9818403477 16956363 17151092
MESH:D007249 Inflammation Dietary Fats 36.9820412841
MESH:D007249 Inflammation Diethylnitrosamine 36.9818785209
MESH:D007249 Inflammation Flavonoids 36.9817296493
MESH:D007249 Inflammation Hydrochloric Acid 36.9811574821
MESH:D007249 Inflammation Lipopolysaccharides 36.9817963957 12878042 17255318 17237260 9205823
MESH:D007249 Inflammation Mustard Gas 36.9811402378 17524151 11428631 9260866 9357497 11428620 16001271 8975870 11428647
MESH:D007249 Inflammation Plant Extracts 36.9816366677 19332304 15997105 12787963
MESH:D007249 Inflammation polyphenols 36.9816366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 36.9812878042 12200463
MESH:D007249 Inflammation Zymosan 36.988014878 11289658
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.0318596194 18200517
MESH:D007251 Influenza, Human Quercetin 4.0716624496
MESH:D007333 Insulin Resistance Dietary Fats 6.4211836018 18457598
MESH:D007333 Insulin Resistance Estradiol 6.4216393666 16627594
MESH:D007410 Intestinal Diseases Hydrochloric Acid 8.7311574821
MESH:D007410 Intestinal Diseases Tretinoin 8.7317994277
MESH:D007414 Intestinal Neoplasms Curcumin 8.8710783313
MESH:D007414 Intestinal Neoplasms Plant Extracts 8.8712628509 12584176 12351151
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.2317255318
MESH:D043183 Irritable Bowel Syndrome Zymosan 5.4117553498
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.589022650 8074119
MESH:D007569 Jaw Abnormalities Ethanol 14.9515513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 14.9516580747
MESH:D007569 Jaw Abnormalities Tretinoin 14.9517551590 15992940
MESH:D007627 Keloid Quercetin 4.5317086741
MESH:D007674 Kidney Diseases Estradiol 5.3715618244
MESH:D007674 Kidney Diseases Quercetin 5.3716962696
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 6.216582329
MESH:D007680 Kidney Neoplasms Estradiol 6.2115610895
MESH:D007818 Laryngeal Diseases Hydrochloric Acid 5.9216498863
MESH:D007826 Laryngismus Hydrochloric Acid 5.9211510729
MESH:D007859 Learning Disorders Ethanol 3.7915451040
MESH:D007889 Leiomyoma Curcumin 4.1718555241
MESH:D007938 Leukemia arsenic trioxide 13.1215070760
MESH:D007938 Leukemia Curcumin 13.1218462866
MESH:D007938 Leukemia Quercetin 13.1217468513
MESH:D007938 Leukemia Tretinoin 13.1217143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 14.1717077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 14.1716106398
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Docosahexaenoic Acids 14.1717077332
MESH:D007948 Leukemia, Monocytic, Acute anthra(1,9-cd)pyrazol-6(2H)-one 10.3416972261
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 10.3416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1114633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 8.2019077051
MESH:D007951 Leukemia, Myeloid Tretinoin 8.2016932348 16482212 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.5716968895 16467208 20471514 17050201 19850784
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.5719850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 6.6815748426 19035177 17869043 16823087 15622746 19075265 16966277 19642359 15213294 16112521 16891316 9834237 17217047 16330433 12679006 17649720 16331271 11468182 19225113 12712474 11161223 17107899 12018890 17712046 15336539
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 6.6815748426 19035177 16331271 16891316 19225113 9834237 17368321 17339181 17301526 17712046 12679006 17649720 16766008 16823087 19075265 17294898 17217047 19642359 17506722 17107899 19029980 16788101 16140955 17361223 16935935
MESH:D015458 Leukemia, T-Cell arsenic trioxide 10.3516882451
MESH:D015458 Leukemia, T-Cell Curcumin 10.3516106398
MESH:D007970 Leukopenia Lipopolysaccharides 4.2715821434
MESH:D007984 Leydig Cell Tumor vinclozolin 4.3016417039
MESH:D017880 Limb Deformities, Congenital Ethanol 7.2817676605
MESH:D017880 Limb Deformities, Congenital Tretinoin 7.289224671
MESH:D008103 Liver Cirrhosis Dietary Fats 18.1518296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 18.1518522880 18407596 18665156 20032147 19638242
MESH:D008103 Liver Cirrhosis Ethanol 18.1515289165
MESH:D008103 Liver Cirrhosis Hydrochloric Acid 18.1516984587
MESH:D008103 Liver Cirrhosis Plant Extracts 18.1517157831
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.6618295389
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.929327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 14.3817355460 18705752 18006644
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 14.3814659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 14.3818166357
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 14.3812878042
MESH:D008106 Liver Cirrhosis, Experimental Methionine 14.3815158331
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 14.3815479170
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 14.3812741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 14.3812878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 14.3818397230 16248980
MESH:D008107 Liver Diseases Curcumin 14.2016956363
MESH:D008107 Liver Diseases Diethylnitrosamine 14.2017034775
MESH:D008107 Liver Diseases Docosahexaenoic Acids 14.2017056761
MESH:D008107 Liver Diseases Folic Acid 14.2016877991
MESH:D008107 Liver Diseases Plant Extracts 14.2017034775
MESH:D008107 Liver Diseases polyphenols 14.2016698588
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.2317207112 17347304
MESH:D008113 Liver Neoplasms arsenic trioxide 15.6514682389
MESH:D008113 Liver Neoplasms Clofibric Acid 15.6517602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 15.6521071580 19255062 18977376 21047994 12112319 18978307 15175105 20492335 19642983 16942905 19638242 19996281 18644402 20118626 20137499 10737359 19499222 20405173 19294768 19256749 21278145 19833225 19426721 19427195 2862719 15885732 18648771 20434301 20101389 19850985 12771043 19812893 19254457 9163691 18754104 19073162 19690152 20583210 19090486 20452335 19551842 20501860 2422723 21167192
MESH:D008113 Liver Neoplasms Plant Extracts 15.6519168119
MESH:D008113 Liver Neoplasms Quercetin 15.6518980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 15.6516984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 19.796587162 1399818 598648 3712494
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 19.7920377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 19.7918308698 18775883 17942915 16267830 21159647 19009564 19126423 18079962 17174075 9362446 18253720 19519916 18164116 19539802 19004024 2563599 17854601 18282651 3124819 18544905 18093689 16842330
MESH:D008114 Liver Neoplasms, Experimental kojic acid 19.7918544905
MESH:D008114 Liver Neoplasms, Experimental Quercetin 19.7919519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 19.7912151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.0215213294
MESH:D008171 Lung Diseases Hydrochloric Acid 6.9716784557
MESH:D008171 Lung Diseases Mustard Gas 6.9718702808 18161513
MESH:D055370 Lung Injury Hydrochloric Acid 8.1819262391 17627322 21311175 18497604 15044056 21114838 18339021 15607125 18573544 11395602 16129981 15090967 19644408 20597076
MESH:D055370 Lung Injury Lipopolysaccharides 8.1821114838
MESH:D008175 Lung Neoplasms arsenic trioxide 9.7019825857 11798837
MESH:D008175 Lung Neoplasms Curcumin 9.7018462866 19359593 16243823
MESH:D008175 Lung Neoplasms Diethylnitrosamine 9.706695378 20970405 20512841 21163286
MESH:D008175 Lung Neoplasms Mustard Gas 9.703148597 8781369
MESH:D008175 Lung Neoplasms Plant Extracts 9.7020869020
MESH:D008175 Lung Neoplasms Quercetin 9.7016280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 9.7011884234 19555203
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.2117718048
MESH:D008223 Lymphoma Curcumin 3.2818462866
MESH:D016399 Lymphoma, T-Cell Curcumin 4.2716173963
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.2917203775 11408345 16891317 11807958
MESH:D020149 Manganese Poisoning Estradiol 4.0419453300
MESH:D019767 Maxillofacial Abnormalities Folic Acid 5.2616832597
MESH:D008527 Medulloblastoma Tretinoin 2.6017453147
MESH:D008545 Melanoma Curcumin 3.2017885582 18462866
MESH:D008545 Melanoma Tretinoin 3.2016752155
MESH:D008569 Memory Disorders Curcumin 8.4017263510
MESH:D008569 Memory Disorders Ethanol 8.4018411066 15451040
MESH:D008591 Meningomyelocele Tretinoin 4.0016940565
MESH:D009101 Multiple Myeloma arsenic trioxide 6.4119417148 15949261 14977855 11468182 19549372
MESH:D009101 Multiple Myeloma Curcumin 6.4119372569
MESH:D009102 Multiple Organ Failure Zymosan 4.8118160304 12879239 15259001 12130978 10890648 10479408 17724436 15241586 15213630 15834315
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.4917962980
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.2318349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.5416105982 16882451
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.5417596541
MESH:D009203 Myocardial Infarction Hydrochloric Acid 5.6918534312
MESH:D009203 Myocardial Infarction Quercetin 5.6919595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.4616810080
MESH:D015428 Myocardial Reperfusion Injury Quercetin 7.4619207477
MESH:D009336 Necrosis Trinitrotoluene 4.3418551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 8.9716624393
MESH:D009361 Neoplasm Invasiveness Curcumin 8.9718495463
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.083581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.083581430 9029167
MESH:D009369 Neoplasms Quercetin 4.4815185748
MESH:D009369 Neoplasms Tretinoin 4.4816946489 16594593
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 4.1012497104
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3017289903
MESH:D009421 Nervous System Malformations Estradiol 13.9611399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 13.9614600291
MESH:D009421 Nervous System Malformations Tretinoin 13.969125849
MESH:D009423 Nervous System Neoplasms Curcumin 5.1918462866
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 15.016679447
MESH:D009436 Neural Tube Defects arsenic trioxide 15.0110525206
MESH:D009436 Neural Tube Defects Folic Acid 15.0117438019
MESH:D009436 Neural Tube Defects Tretinoin 15.019142499
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 4.7617168769
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 2.9920387270
MESH:D020078 Neurogenic Inflammation Quercetin 3.9617929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6820387270
MESH:D009503 Neutropenia Folic Acid 8.2816322990
MESH:D009503 Neutropenia Mustard Gas 8.287688884 16761898
MESH:D009765 Obesity Curcumin 6.8819297423
MESH:D009765 Obesity Dietary Fats 6.8816723640 20132043 18457598 21332399 17217161 18674790 11836018 20518802 19632207
MESH:D009765 Obesity Plant Extracts 6.8820132043 19056576
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 13.216482804 4026338
MESH:D009784 Occupational Diseases Hydrochloric Acid 13.2112378975
MESH:D009784 Occupational Diseases Trinitrotoluene 13.2114694615 12819281 17852074
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.583988306
MESH:D010024 Osteoporosis Curcumin 3.2018719352
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 3.8219495926
MESH:D010051 Ovarian Neoplasms arsenic trioxide 13.3512452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Curcumin 13.3519020741 18462866
MESH:D010051 Ovarian Neoplasms Estradiol 13.3519401270
MESH:D010051 Ovarian Neoplasms Quercetin 13.3519005980
MESH:D010051 Ovarian Neoplasms Tretinoin 13.3516936753
MESH:D010146 Pain Tretinoin 2.5716870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 18.2815580305
MESH:D010190 Pancreatic Neoplasms Curcumin 18.2819196508 19401701 17440100
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 18.2816540662
MESH:D010190 Pancreatic Neoplasms Ethanol 18.2812384795
MESH:D010190 Pancreatic Neoplasms Quercetin 18.2816965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 18.2815976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2911578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 8.077296757
MESH:D010212 Papilloma Plant Extracts 8.0716517061 15173996
MESH:D010235 Paraganglioma arsenic trioxide 3.7619927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8112520081
MESH:D010538 Peritonitis Zymosan 4.4614761945 17826846 15979727 18557954 17371808 19641140 11985352 19088179 15259001 18760300 18977430
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.036228378
MESH:D011014 Pneumonia Lipopolysaccharides 4.1212224865 11605937
MESH:D011015 Pneumonia, Aspiration Hydrochloric Acid 4.9418497604 15970105 15607125 18573544
MESH:D011041 Poisoning Mustard Gas 3.4115727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1518163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.022563599
MESH:D011230 Precancerous Conditions Quercetin 8.0219056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.0611896295 11118676 11222880 11399792
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 8.0619015723 18220299 18042343
MESH:D011469 Prostatic Diseases vinclozolin 4.5018220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5020887781
MESH:D011471 Prostatic Neoplasms marker/mechanism 17728788
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.9319131511
MESH:D011471 Prostatic Neoplasms Curcumin 1.9318769126 11398177 18226269 15129424 12497104 10851300 18156803
MESH:D011471 Prostatic Neoplasms Estradiol 1.9316740699
MESH:D011471 Prostatic Neoplasms Plant Extracts 1.9317804756 14666653
MESH:D011471 Prostatic Neoplasms Quercetin 1.9314715546 17292933
MESH:D011472 Prostatitis vinclozolin 4.5018629315
MESH:D011507 Proteinuria Tretinoin 3.2116636307
MESH:D011537 Pruritus Ethinyl Estradiol 8.1015861022 16919318
MESH:D011537 Pruritus Mustard Gas 8.1018058305
MESH:D011625 Pterygium Tretinoin 4.3616723453
MESH:D001261 Pulmonary Atelectasis Hydrochloric Acid 5.5820597076
MESH:D011654 Pulmonary Edema Hydrochloric Acid 4.7815090967
MESH:D011656 Pulmonary Emphysema Curcumin 4.1519168576
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.7517894541 10334151 17266442 17620002 17720292
MESH:D051437 Renal Insufficiency Folic Acid 4.3615728788
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 8.2610666014 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Hydrochloric Acid 8.2617627322 18339021 16784557 18549715 16129981
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.4410835634
MESH:D012133 Respiratory Paralysis Hydrochloric Acid 5.9211510729
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4318990726
MESH:D012140 Respiratory Tract Diseases Hydrochloric Acid 4.7320516732
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.053692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.7016283617 16116481
MESH:D012509 Sarcoma Curcumin 3.7418462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.5516646077
MESH:D012554 Schistosomiasis japonica Quercetin 5.1116862918
MESH:D012559 Schizophrenia Folic Acid 4.2216641680
MESH:D012559 Schizophrenia Methionine 4.2215737665
MESH:D012640 Seizures Ethanol 5.469754883
MESH:D012640 Seizures Trinitrotoluene 5.4618551238
MESH:D018805 Sepsis therapeutic 9892616
MESH:D018805 Sepsis Curcumin 8.5218389075
MESH:D018805 Sepsis Zymosan 8.5211441115
MESH:D012871 Skin Diseases Folic Acid 4.9018709164
MESH:D012871 Skin Diseases Mustard Gas 4.9012880345 15451306 16961503
MESH:D012878 Skin Neoplasms Plant Extracts 8.2815173996 16517061
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.2816192470
MESH:D012878 Skin Neoplasms Tretinoin 8.2816467112
MESH:D013088 Spermatocele Ethinyl Estradiol 3.5016709447
MESH:D013118 Spinal Cord Diseases Folic Acid 5.0616361298
MESH:D013163 Splenomegaly Trinitrotoluene 4.7815817613
MESH:D013274 Stomach Neoplasms arsenic trioxide 7.6117007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 7.6118456281
MESH:D013274 Stomach Neoplasms Docosahexaenoic Acids 7.6119015929
MESH:D013274 Stomach Neoplasms Ethanol 7.6118456281
MESH:D013274 Stomach Neoplasms Folic Acid 7.6117171786
MESH:D013274 Stomach Neoplasms Tretinoin 7.6117261132
MESH:D013276 Stomach Ulcer Curcumin 14.1516631530 19188055
MESH:D013276 Stomach Ulcer Ethanol 14.1517918041 17189318 16755016 9211565 11906479 9562338
MESH:D013276 Stomach Ulcer Hydrochloric Acid 14.1515309881 16755016 17189318
MESH:D013276 Stomach Ulcer Plant Extracts 14.1517135157 15255614 18193104 12787963 18237397
MESH:D020521 Stroke Folic Acid 3.9916517955
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.889754883
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 11.8117997062
MESH:D013705 Temporomandibular Joint Disorders polyphenols 11.8117997062
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.7915821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7915669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4612697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 14.406587162 6582329 7505956 1399818 3712494
MESH:D013964 Thyroid Neoplasms arsenic trioxide 14.4019014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 14.407505956
MESH:D013964 Thyroid Neoplasms Tretinoin 14.4016026305 17045167
MESH:D013978 Tibial Fractures Estradiol 4.2519048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.4116051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.5315213294
MESH:D014376 Tuberculosis Tretinoin 2.9516040207
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 10.448074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 10.4412973940 11780464 20435036 12845720
MESH:D001749 Urinary Bladder Neoplasms Curcumin 10.4418593936
MESH:D001749 Urinary Bladder Neoplasms Quercetin 10.4416720314
MESH:D014565 Urogenital Neoplasms Curcumin 4.8318462866
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.3016129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.8914692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.1716752155
MESH:D014605 Uveitis Zymosan 4.9611006244
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1512125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1514671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 4.3318097624
MESH:D020257 Ventricular Remodeling Plant Extracts 4.8818097624
MESH:D014820 Vitiligo Tretinoin 3.6516761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8115886252
MESH:D015430 Weight Gain Dietary Fats 3.3816723640
MESH:D009396 Wilms Tumor Tretinoin 3.6016287080
MESH:D014947 Wounds and Injuries Plant Extracts 3.9020213670 19894650
Pathway ID Pathway Name
KEGG:00360 Phenylalanine metabolism
KEGG:00350 Tyrosine metabolism
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB01880 - 3,4-Dihydroxycinnamic Acid Antioxidants
DB02728 - 7-Hydroxy-2-Oxo-Chromene-3-Carboxylic Acid Ethyl Ester
DB04272 - Citric Acid Anticoagulants;Chelating Agents
DB07718 - 3-(4-HYDROXY-PHENYL)PYRUVIC ACID
DB07888 - 3-(4-HYDROXYPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE-ACETIC ACID METHYL ESTER
DB08333 - 4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME
DB08334 - 3-FLUORO-4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME
DB08335 - 4-HYDROXYBENZALDEHYDE O-(3,3-DIMETHYLBUTANOYL)OXIME
DB08765 - 6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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