Annotation Detail for ACHE
Basic Information Top
| Gene Symbol: | ACHE ( ARACHE,N-ACHE,YT ) |
|---|---|
| Gene Full Name: | acetylcholinesterase |
| Band: | 7q22.1 |
| Quick Links | Entrez ID:43; OMIM: 100740; Uniprot ID:ACES_HUMAN; ENSEMBL ID: ENSG00000087085; HGNC ID: 108 |
| Relate to Another Database: | SFARIGene; denovo-db |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| hsa00564 | Glycerophospholipid metabolism |
| Pathway ID | Pathway Name |
|---|---|
| Synaptic Transmission |
| Pathway ID | Pathway Name |
|---|---|
| 200116 | ATF-2 transcription factor network |
| Pathway ID | Pathway Name |
|---|---|
| P00042 | Muscarinic acetylcholine receptor 1 and 3 signaling pathway |
| P00044 | Nicotinic acetylcholine receptor signaling pathway |
| P00043 | Muscarinic acetylcholine receptor 2 and 4 signaling pathway |
| Pathway ID | Pathway Name |
|---|---|
| 500154 | Neurotransmitter Clearance In The Synaptic Cleft |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C403065 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide results in decreased activity of ACHE protein | decreases activity | 15525694 |
| C416723 | 2-((((4,6-dimethoxy-(2-pyrimidinyl)amino)carbonyl)amino)sulfonyl)-N,N-dimethyl-3-pyridinecarboxamide | 2-((((4,6-dimethoxy-(2-pyrimidinyl)amino)carbonyl)amino)sulfonyl)-N,N-dimethyl-3-pyridinecarboxamide results in decreased activity of ACHE protein | decreases activity | 11023689 |
| C106572 | 3-iodo-2-propynylbutylcarbamate | 3-iodo-2-propynylbutylcarbamate results in increased activity of ACHE protein | increases activity | 15261450 |
| C024836 | 4-nitrophenol | 4-nitrophenol results in increased activity of ACHE protein | increases activity | 9352214 |
| C024836 | 4-nitrophenol | 4-nitrophenol results in increased activity of ACHE protein | increases activity | 9352214 |
| C024836 | 4-nitrophenol | 4-nitrophenol results in increased activity of ACHE protein | increases activity | 9352214 |
| C024836 | 4-nitrophenol | 4-nitrophenol results in increased activity of ACHE protein | increases activity | 9352214 |
| C001969 | acephate | acephate binds to and results in increased phosphorylation of and results in decreased activity of ACHE protein | affects binding|decreases activity|increases phosphorylation | 2097819 |
| C001969 | acephate | acephate results in decreased activity of ACHE protein | decreases activity | 18569613 |
| C001969 | acephate | acephate results in decreased activity of ACHE protein | decreases activity | 2284053 10681099 |
| C001969 | acephate | HI 6 inhibits the reaction [acephate results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 10681099 |
| C001969 | acephate | pralidoxime inhibits the reaction [acephate results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 10681099 |
| C001969 | acephate | Trimedoxime inhibits the reaction [acephate results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 10681099 |
| C001969 | acephate | methamidophos inhibits the reaction [acephate results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 9074804 |
| C001969 | acephate | acephate results in decreased activity of ACHE protein | decreases activity | 11048668 12039681 |
| C001969 | acephate | acephate binds to ACHE protein | affects binding | 3798464 |
| C001969 | acephate | acephate inhibits the reaction [methamidophos binds to and results in decreased activity of ACHE protein] | affects binding|decreases activity|decreases reaction | 3798464 |
| D000079 | Acetaldehyde | Acetaldehyde results in decreased activity of ACHE protein | decreases activity | 17888594 |
| D000079 | Acetaldehyde | Acetaldehyde results in decreased activity of ACHE protein | decreases activity | 8292740 |
| D000109 | Acetylcholine | ACHE protein results in increased hydrolysis of Acetylcholine | increases hydrolysis | 1909249 |
| D000109 | Acetylcholine | ACHE protein results in increased hydrolysis of Acetylcholine | increases hydrolysis | 15811534 |
| D000109 | Acetylcholine | ACHE protein results in increased hydrolysis of Acetylcholine | increases hydrolysis | 15811534 |
| D000109 | Acetylcholine | ACHE protein results in increased hydrolysis of Acetylcholine | increases hydrolysis | 15811534 |
| D000122 | Acetylthiocholine | ACHE protein results in increased metabolism of Acetylthiocholine | increases metabolic processing | 18433895 |
| D000122 | Acetylthiocholine | Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide inhibits the reaction [ACHE protein results in increased metabolism of Acetylthiocholine] | decreases reaction|increases metabolic processing | 18433895 |
| D000122 | Acetylthiocholine | Dichlorvos inhibits the reaction [ACHE protein results in increased metabolism of Acetylthiocholine] | decreases reaction|increases metabolic processing | 18433895 |
| D000122 | Acetylthiocholine | Physostigmine analog inhibits the reaction [ACHE protein results in increased metabolism of Acetylthiocholine] | decreases reaction|increases metabolic processing | 18433895 |
| D000122 | Acetylthiocholine | ACHE protein results in increased metabolism of Acetylthiocholine | increases metabolic processing | 16966160 |
| D000122 | Acetylthiocholine | ACHE protein results in increased metabolism of Acetylthiocholine | increases metabolic processing | 12389909 |
| C065959 | AFDX 384 | AFDX 384 affects the reaction [donepezil affects the activity of ACHE protein] | affects activity|affects reaction | 12111444 |
| C065959 | AFDX 384 | AFDX 384 affects the reaction [rivastigmine affects the activity of ACHE protein] | affects activity|affects reaction | 12111444 |
| C065959 | AFDX 384 | AFDX 384 results in increased activity of ACHE protein | increases activity | 12111444 |
| C000188 | alachlor | alachlor results in increased activity of ACHE protein | increases activity | 16998629 |
| C000188 | alachlor | alachlor results in increased expression of ACHE mRNA | increases expression | 12419858 |
| D000420 | Albuterol | Albuterol promotes the reaction [Physostigmine results in increased secretion of ACHE protein] | increases reaction|increases secretion | 17158603 |
| D000448 | Aldicarb | Aldicarb results in decreased activity of ACHE protein | decreases activity | 16256972 8134223 |
| D000448 | Aldicarb | Aldicarb results in decreased activity of ACHE protein | decreases activity | 14644616 |
| D000448 | Aldicarb | Aldicarb results in decreased activity of ACHE protein | decreases activity | 10871426 |
| D000535 | Aluminum | Aluminum promotes the reaction [Lead results in decreased activity of ACHE protein] | decreases activity|increases reaction | 15266904 |
| D006710 | Homocysteine | Homocysteine results in increased activity of ACHE protein | increases activity | 16375580 |
| C006632 | arsenic trioxide | arsenic trioxide results in decreased activity of ACHE protein | decreases activity | 16916622 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased activity of ACHE protein | increases activity | 16916622 |
| C006632 | arsenic trioxide | Selenium inhibits the reaction [arsenic trioxide results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16916622 |
| D001205 | Ascorbic Acid | Ascorbic Acid results in decreased activity of ACHE protein | decreases activity | 16822217 |
| D001205 | Ascorbic Acid | Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16248992 |
| D001218 | Aspartame | Aspartame metabolite results in decreased activity of ACHE protein | decreases activity | 17580119 17673349 |
| D001218 | Aspartame | Aspartame metabolite results in decreased activity of ACHE protein | decreases activity | 16129618 |
| D001218 | Aspartame | Aspartame metabolite results in decreased activity of ACHE protein | decreases activity | 17673349 17580119 |
| D001280 | Atrazine | Atrazine promotes the reaction [Chlorpyrifos results in decreased activity of ACHE protein] | decreases activity|increases reaction | 11534899 |
| D001280 | Atrazine | [Chlorpyrifos co-treated with cyanazine co-treated with Atrazine] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 11878473 |
| D001280 | Atrazine | [Atrazine co-treated with Chlorpyrifos] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 12109753 |
| D001280 | Atrazine | [Atrazine co-treated with Diazinon] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 12109753 |
| D001280 | Atrazine | [Atrazine co-treated with Methyl Parathion] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 12109753 |
| D001285 | Atropine | Atropine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 2241428 |
| D001285 | Atropine | [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of ACHE protein | affects cotreatment|decreases expression | 17963125 |
| D001285 | Atropine | Atropine inhibits the reaction [Organophosphorus Compounds results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16293236 |
| C072763 | azamethiphos | azamethiphos results in decreased activity of ACHE protein | decreases activity | 17615116 |
| D001387 | Azinphosmethyl | Azinphosmethyl results in decreased activity of ACHE protein | decreases activity | 15041264 |
| D001387 | Azinphosmethyl | Azinphosmethyl results in decreased activity of ACHE protein | decreases activity | 8658539 |
| C007725 | bendiocarb | bendiocarb results in decreased activity of ACHE protein | decreases activity | 1909249 |
| C007725 | bendiocarb | bendiocarb results in decreased activity of ACHE protein | decreases activity | 14644616 |
| D002093 | Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide | Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide inhibits the reaction [ACHE protein results in increased metabolism of Acetylthiocholine] | decreases reaction|increases metabolic processing | 18433895 |
| D002093 | Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide | Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide results in decreased activity of ACHE protein | decreases activity | 18433895 |
| D002093 | Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide | Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide inhibits the reaction [tert-Butylhydroperoxide results in increased secretion of ACHE protein] | decreases reaction|increases secretion | 16903848 |
| D002093 | Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide | Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide results in decreased activity of ACHE protein | decreases activity | 18761328 |
| D002093 | Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide | Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide results in decreased activity of ACHE protein | decreases activity | 15811534 |
| D002093 | Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide | Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide results in decreased activity of ACHE protein | decreases activity | 15811534 |
| D002093 | Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide | Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide results in decreased activity of ACHE protein | decreases activity | 15811534 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of ACHE mRNA | decreases expression | 20106945 |
| C095105 | bexarotene | bexarotene results in decreased expression of ACHE mRNA | decreases expression | 16648578 |
| D020122 | tert-Butylhydroperoxide | Benzenaminium, 4,4'-(3-oxo-1,5-pentanediyl)bis(N,N-dimethyl-N-2-propenyl-), Dibromide inhibits the reaction [tert-Butylhydroperoxide results in increased secretion of ACHE protein] | decreases reaction|increases secretion | 16903848 |
| D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide results in increased expression of ACHE mRNA alternative form | increases expression | 16903848 |
| D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide results in increased secretion of ACHE protein | increases secretion | 16903848 |
| D002104 | Cadmium | Cadmium results in decreased activity of ACHE protein | decreases activity | 16828738 |
| D002104 | Cadmium | Cadmium results in decreased activity of ACHE protein | decreases activity | 16828738 |
| D002104 | Cadmium | Cadmium promotes the reaction [Carbofuran results in decreased activity of ACHE protein] | decreases activity|increases reaction | 16257038 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in decreased activity of ACHE protein | decreases activity | 11281253 |
| D012721 | Carbaryl | Carbaryl results in decreased activity of ACHE protein | decreases activity | 15041264 |
| D012721 | Carbaryl | Carbaryl results in decreased activity of ACHE protein | decreases activity | 1586462 2511899 |
| D012721 | Carbaryl | Carbaryl results in decreased activity of ACHE protein | decreases activity | 8561923 |
| D012721 | Carbaryl | ACHE protein affects the susceptibility to Carbaryl | affects response to substance | 8016090 |
| D012721 | Carbaryl | ACHE protein mutant form results in decreased susceptibility to Carbaryl | decreases response to substance | 8016090 |
| D012721 | Carbaryl | Carbaryl results in decreased activity of ACHE protein | decreases activity | 17590326 |
| D012721 | Carbaryl | Carbaryl results in decreased activity of ACHE protein | decreases activity | 16256972 |
| D012721 | Carbaryl | Carbaryl results in decreased activity of ACHE protein | decreases activity | 1833318 |
| D012721 | Carbaryl | Carbaryl results in decreased activity of ACHE protein | decreases activity | 17294923 |
| D012721 | Carbaryl | Carbaryl results in decreased activity of ACHE protein | decreases activity | 11841371 |
| D012721 | Carbaryl | Carbaryl results in decreased activity of ACHE protein | decreases activity | 11841371 |
| D012721 | Carbaryl | Carbaryl results in decreased activity of ACHE protein | decreases activity | 14644616 |
| D002235 | Carbofuran | ACHE protein mutant form results in decreased susceptibility to Carbofuran | decreases response to substance | 9371089 |
| D002235 | Carbofuran | Carbofuran results in decreased activity of ACHE protein | decreases activity | 17364237 |
| D002235 | Carbofuran | Carbofuran results in decreased activity of ACHE protein | decreases activity | 11023689 16461013 |
| D002235 | Carbofuran | Cadmium promotes the reaction [Carbofuran results in decreased activity of ACHE protein] | decreases activity|increases reaction | 16257038 |
| D002235 | Carbofuran | Carbofuran results in decreased activity of ACHE protein | decreases activity | 16257038 |
| D002235 | Carbofuran | Carbofuran results in decreased activity of ACHE protein | decreases activity | 15261450 |
| D002235 | Carbofuran | Carbofuran results in decreased activity of ACHE protein | decreases activity | 7966439 10918524 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in decreased activity of ACHE protein | decreases activity | 16496349 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of ACHE mRNA | increases expression | 12832660 |
| C035038 | carbosulfan | carbosulfan results in decreased activity of ACHE protein | decreases activity | 16461013 |
| C035038 | carbosulfan | carbosulfan results in decreased activity of ACHE protein | decreases activity | 16402316 16753212 |
| C035038 | carbosulfan | carbosulfan results in decreased activity of ACHE protein | decreases activity | 3710030 |
| C103481 | chebulinic acid | chebulinic acid results in decreased expression of ACHE protein | decreases expression | 14769215 |
| D002709 | Chlorfenvinphos | Chlorfenvinphos results in decreased activity of ACHE protein | decreases activity | 17615116 |
| D002709 | Chlorfenvinphos | Chlorfenvinphos results in decreased activity of ACHE protein | decreases activity | 8783813 |
| D002709 | Chlorfenvinphos | HI 6 inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D002709 | Chlorfenvinphos | HLo 7 inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D002709 | Chlorfenvinphos | Obidoxime Chloride inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D002709 | Chlorfenvinphos | pralidoxime inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C072795 | chlorodifluoroacetaldehyde | chlorodifluoroacetaldehyde results in decreased activity of ACHE protein | decreases activity | 8292740 |
| D020111 | Chlorodiphenyl (54% Chlorine) | Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16248992 |
| D020111 | Chlorodiphenyl (54% Chlorine) | Chlorodiphenyl (54% Chlorine) results in decreased activity of ACHE protein | decreases activity | 16248992 |
| D004390 | Chlorpyrifos | Atrazine promotes the reaction [Chlorpyrifos results in decreased activity of ACHE protein] | decreases activity|increases reaction | 11534899 |
| D004390 | Chlorpyrifos | [Chlorpyrifos co-treated with cyanazine co-treated with Atrazine] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 11878473 |
| D004390 | Chlorpyrifos | Chlorpyrifos results in decreased activity of ACHE protein | decreases activity | 11534899 16865602 |
| D004390 | Chlorpyrifos | [Chlorpyrifos co-treated with terbutylazine] results in decreased expression of ACHE protein | affects cotreatment|decreases expression | 16085276 |
| D004390 | Chlorpyrifos | Chlorpyrifos results in decreased expression of ACHE protein | decreases expression | 16085276 |
| D004390 | Chlorpyrifos | Chlorpyrifos results in decreased activity of ACHE protein | decreases activity | 10681099 |
| D004390 | Chlorpyrifos | [Atrazine co-treated with Chlorpyrifos] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 12109753 |
| D004390 | Chlorpyrifos | Chlorpyrifos results in decreased activity of ACHE protein | decreases activity | 16783542 |
| D004390 | Chlorpyrifos | Chlorpyrifos results in decreased activity of ACHE protein | decreases activity | 15178118 16011852 |
| D004390 | Chlorpyrifos | Chlorpyrifos results in decreased activity of ACHE protein | decreases activity | 16753212 16402316 |
| D004390 | Chlorpyrifos | Chlorpyrifos results in decreased activity of ACHE protein | decreases activity | 11405414 15342957 15207377 17110060 |
| D004390 | Chlorpyrifos | Chlorpyrifos results in increased expression of ACHE mRNA | increases expression | 18812211 |
| D004390 | Chlorpyrifos | Chlorpyrifos results in increased expression of ACHE mRNA alternative form | increases expression | 17366821 |
| D004390 | Chlorpyrifos | [Methyl Parathion co-treated with Chlorpyrifos] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 11405414 |
| C074702 | chromium hexavalent ion | chromium hexavalent ion results in decreased activity of ACHE protein | decreases activity | 16785179 |
| D009249 | NADP | [Methyl Parathion co-treated with NADP] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 11684353 |
| D003300 | Copper | Copper results in decreased activity of ACHE protein | decreases activity | 16828738 |
| D003300 | Copper | Copper results in decreased activity of ACHE protein | decreases activity | 16828738 |
| D003300 | Copper | Copper results in decreased activity of ACHE protein | decreases activity | 16257038 |
| D019327 | Copper Sulfate | Copper Sulfate results in decreased activity of ACHE protein | decreases activity | 16828738 |
| D019327 | Copper Sulfate | Copper Sulfate results in decreased activity of ACHE protein | decreases activity | 16023296 |
| D003372 | Coumaphos | Coumaphos results in decreased activity of ACHE protein | decreases activity | 10509429 |
| C073267 | crufomate | crufomate results in decreased activity of ACHE protein | decreases activity | 7059283 |
| C007168 | cyanazine | [Chlorpyrifos co-treated with cyanazine co-treated with Atrazine] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 11878473 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of ACHE mRNA | increases expression | 20106945 |
| C017160 | cypermethrin | cypermethrin results in decreased activity of ACHE protein | decreases activity | 2365420 |
| C017160 | cypermethrin | cypermethrin results in decreased activity of ACHE protein | decreases activity | 12524023 |
| C017160 | cypermethrin | cypermethrin affects the activity of ACHE protein | affects activity | 10355540 |
| C017160 | cypermethrin | [cypermethrin co-treated with fenvalerate] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 10355540 |
| C017160 | cypermethrin | cypermethrin results in decreased activity of ACHE protein | decreases activity | 8385837 |
| C017160 | cypermethrin | cypermethrin results in increased activity of ACHE protein | increases activity | 7595515 |
| C017160 | cypermethrin | cypermethrin results in decreased activity of ACHE protein | decreases activity | 2365420 |
| C017180 | decamethrin | [methamidophos co-treated with decamethrin] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 12191869 |
| C017180 | decamethrin | [Methyl Parathion co-treated with decamethrin] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 12191869 |
| D003671 | DEET | [DEET co-treated with Permethrin] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 11248143 14713564 |
| D003671 | DEET | [DEET co-treated with Permethrin] results in increased activity of ACHE protein | affects cotreatment|increases activity | 14713564 |
| D003671 | DEET | DEET results in increased activity of ACHE protein | increases activity | 14713564 |
| D003671 | DEET | [Pyridostigmine Bromide co-treated with DEET] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 11248143 |
| D003671 | DEET | [Pyridostigmine Bromide co-treated with DEET] results in increased activity of ACHE protein | affects cotreatment|increases activity | 14751452 |
| D003671 | DEET | [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 11248143 14751452 |
| D003671 | DEET | [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in increased activity of ACHE protein | affects cotreatment|increases activity | 14751452 |
| C030064 | demeton-S-methyl | demeton-S-methyl results in decreased activity of ACHE protein | decreases activity | 16766477 |
| C521776 | Desmodium gangeticum extract | Desmodium gangeticum extract results in decreased activity of ACHE protein | decreases activity | 16946593 |
| D003976 | Diazinon | Diazinon results in decreased activity of ACHE protein | decreases activity | 17615116 |
| D003976 | Diazinon | Diazinon results in decreased activity of ACHE protein | decreases activity | 15683842 |
| D003976 | Diazinon | Diazinon affects the expression of ACHE mRNA | affects expression | 16207942 |
| D003976 | Diazinon | Diazinon results in decreased activity of ACHE protein | decreases activity | 10509429 16207942 |
| D003976 | Diazinon | Diazinon results in decreased activity of ACHE protein | decreases activity | 8658539 |
| D003976 | Diazinon | [Atrazine co-treated with Diazinon] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 12109753 |
| D003976 | Diazinon | Diazinon results in decreased activity of ACHE protein | decreases activity | 17239417 |
| D003976 | Diazinon | Diazinon results in decreased activity of ACHE protein | decreases activity | 17442507 |
| D003976 | Diazinon | Diazinon results in increased expression of ACHE mRNA alternative form | increases expression | 17366821 |
| C000912 | diazoxon | diazoxon results in decreased activity of ACHE protein | decreases activity | 10871426 |
| C012279 | dibutylnitrosamine | dibutylnitrosamine results in increased activity of ACHE protein | increases activity | 15881669 |
| D004006 | Dichlorvos | Dichlorvos inhibits the reaction [ACHE protein results in increased metabolism of Acetylthiocholine] | decreases reaction|increases metabolic processing | 18433895 |
| D004006 | Dichlorvos | Dichlorvos results in decreased activity of ACHE protein | decreases activity | 18433895 |
| D004006 | Dichlorvos | Dichlorvos results in decreased activity of ACHE protein | decreases activity | 18569613 |
| D004006 | Dichlorvos | Dichlorvos results in decreased activity of ACHE protein | decreases activity | 17665685 |
| D004006 | Dichlorvos | Dichlorvos results in decreased activity of ACHE protein | decreases activity | 17533655 |
| D004006 | Dichlorvos | Dichlorvos results in decreased activity of ACHE protein | decreases activity | 17533655 |
| D004006 | Dichlorvos | Dichlorvos results in decreased activity of ACHE protein | decreases activity | 16023296 |
| D004006 | Dichlorvos | Dichlorvos results in decreased activity of ACHE protein | decreases activity | 10509429 |
| D004006 | Dichlorvos | Dichlorvos results in decreased activity of ACHE protein | decreases activity | 16036766 10975133 8783813 19631781 |
| D004006 | Dichlorvos | HI 6 inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D004006 | Dichlorvos | HLo 7 inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D004006 | Dichlorvos | Obidoxime Chloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D004006 | Dichlorvos | pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D004006 | Dichlorvos | Tiapride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16036766 16193528 |
| D004006 | Dichlorvos | Dichlorvos binds to and results in decreased activity of ACHE protein | affects binding|decreases activity | 16598855 |
| D004006 | Dichlorvos | Dichlorvos results in decreased activity of ACHE protein modified form | decreases activity | 10473783 |
| D004006 | Dichlorvos | pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein modified form] | decreases activity|decreases reaction | 10473783 |
| D004006 | Dichlorvos | Dichlorvos results in decreased activity of ACHE protein | decreases activity | 15033007 17188317 17722737 |
| D004006 | Dichlorvos | Dichlorvos results in decreased activity of ACHE protein | decreases activity | 15811534 |
| D004006 | Dichlorvos | Dichlorvos results in decreased activity of ACHE protein | decreases activity | 15811534 |
| D004006 | Dichlorvos | Dichlorvos results in decreased activity of ACHE protein | decreases activity | 15811534 |
| C000944 | dicrotophos | dicrotophos results in decreased activity of ACHE protein | decreases activity | 18569613 |
| C000944 | dicrotophos | dicrotophos results in decreased activity of ACHE protein | decreases activity | 8783813 |
| C000944 | dicrotophos | HI 6 inhibits the reaction [dicrotophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C000944 | dicrotophos | HLo 7 inhibits the reaction [dicrotophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C000944 | dicrotophos | Obidoxime Chloride inhibits the reaction [dicrotophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C000944 | dicrotophos | pralidoxime inhibits the reaction [dicrotophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D004117 | Dimethoate | Dimethoate results in decreased activity of ACHE protein | decreases activity | 18569613 |
| D004117 | Dimethoate | Dimethoate results in decreased activity of ACHE protein | decreases activity | 16257584 |
| D004117 | Dimethoate | Dimethoate results in decreased activity of ACHE protein | decreases activity | 17590326 |
| D004117 | Dimethoate | Dimethoate results in decreased activity of ACHE protein | decreases activity | 16701032 16112538 |
| D004117 | Dimethoate | pralidoxime inhibits the reaction [Dimethoate results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16112538 |
| D004117 | Dimethoate | Dimethoate results in decreased activity of ACHE protein | decreases activity | 16833148 |
| D004117 | Dimethoate | Dimethoate results in decreased activity of ACHE protein | decreases activity | 15779760 |
| D004117 | Dimethoate | Dimethoate results in decreased activity of ACHE protein | decreases activity | 16112789 17997881 15033006 |
| C002302 | dimethoxon | ACHE protein mutant form results in decreased susceptibility to dimethoxon | decreases response to substance | 12144698 |
| C002302 | dimethoxon | dimethoxon results in decreased activity of ACHE protein | decreases activity | 12144698 |
| C002302 | dimethoxon | dimethoxon results in decreased activity of ACHE protein | decreases activity | 18569613 |
| C002302 | dimethoxon | dimethoxon results in decreased activity of ACHE protein | decreases activity | 8783813 |
| C002302 | dimethoxon | HI 6 inhibits the reaction [dimethoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C002302 | dimethoxon | HLo 7 inhibits the reaction [dimethoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C002302 | dimethoxon | Obidoxime Chloride inhibits the reaction [dimethoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C002302 | dimethoxon | pralidoxime inhibits the reaction [dimethoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C002302 | dimethoxon | dimethoxon results in decreased activity of ACHE protein | decreases activity | 11985885 |
| D008559 | Memantine | Memantine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 2241428 |
| D004221 | Disulfiram | Disulfiram results in decreased expression of ACHE protein | decreases expression | 3868355 |
| D004237 | Diuron | Diuron results in decreased activity of ACHE protein | decreases activity | 11023689 |
| C076946 | donepezil | donepezil results in decreased activity of ACHE protein | decreases activity | 14535624 |
| C076946 | donepezil | AFDX 384 affects the reaction [donepezil affects the activity of ACHE protein] | affects activity|affects reaction | 12111444 |
| C076946 | donepezil | donepezil affects the activity of ACHE protein | affects activity | 12111444 |
| D004456 | Echothiophate Iodide | Echothiophate Iodide results in decreased activity of ACHE protein | decreases activity | 1909249 |
| D004491 | Edrophonium | Edrophonium results in decreased activity of ACHE protein | decreases activity | 1909249 |
| D004726 | Endosulfan | Endosulfan results in decreased activity of ACHE protein | decreases activity | 12648478 |
| D004726 | Endosulfan | [Endosulfan co-treated with Malathion] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 2380476 |
| D004726 | Endosulfan | Endosulfan results in decreased activity of ACHE protein | decreases activity | 7900959 |
| C036251 | EPTC | EPTC results in decreased activity of ACHE protein | decreases activity | 14644616 |
| D004958 | Estradiol | Estradiol results in increased expression of ACHE mRNA | increases expression | 20106945 |
| D000431 | Ethanol | Ethanol results in increased activity of ACHE protein | increases activity | 17888594 |
| D005031 | Ethylenethiourea | Ethylenethiourea results in decreased expression of ACHE protein | decreases expression | 3868355 |
| C121104 | ethylparaoxon | ethylparaoxon results in decreased activity of ACHE protein | decreases activity | 18804659 |
| C121104 | ethylparaoxon | Obidoxime Chloride inhibits the reaction [ethylparaoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 18804659 |
| C002698 | fenamiphos | fenamiphos results in decreased activity of ACHE protein | decreases activity | 17382909 |
| C002698 | fenamiphos | fenamiphos binds to and results in increased phosphorylation of and results in decreased activity of ACHE protein | affects binding|decreases activity|increases phosphorylation | 17402711 |
| C007711 | fenitrooxone | fenitrooxone results in decreased activity of ACHE protein | decreases activity | 17294923 |
| C052034 | fenoxycarb | fenoxycarb results in decreased activity of ACHE protein | decreases activity | 14644616 |
| D005284 | Fenthion | Fenthion results in decreased activity of ACHE protein | decreases activity | 14976351 |
| D005284 | Fenthion | Fenthion metabolite results in decreased activity of ACHE protein | decreases activity | 17110060 |
| C017690 | fenvalerate | fenvalerate results in decreased activity of ACHE protein | decreases activity | 2365420 |
| C017690 | fenvalerate | fenvalerate results in decreased activity of ACHE protein | decreases activity | 8739525 |
| C017690 | fenvalerate | fenvalerate results in increased activity of ACHE protein | increases activity | 8739525 |
| C017690 | fenvalerate | [cypermethrin co-treated with fenvalerate] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 10355540 |
| C017690 | fenvalerate | fenvalerate affects the activity of ACHE protein | affects activity | 10355540 |
| C017690 | fenvalerate | fenvalerate results in decreased activity of ACHE protein | decreases activity | 15186033 8385837 |
| C017690 | fenvalerate | fenvalerate results in increased activity of ACHE protein | increases activity | 8385837 |
| C017690 | fenvalerate | fenvalerate results in decreased activity of ACHE protein | decreases activity | 2365420 |
| D005492 | Folic Acid | Folic Acid inhibits the reaction [MTHFR gene polymorphism results in increased activity of ACHE protein] | decreases reaction|increases activity | 16375580 |
| D005702 | Galantamine | Galantamine results in decreased activity of ACHE protein | decreases activity | 16914529 |
| D005702 | Galantamine | [Galantamine results in decreased activity of ACHE protein] which results in decreased susceptibility to Paraoxon | decreases activity|decreases response to substance | 16914529 |
| D005702 | Galantamine | [Galantamine results in decreased activity of ACHE protein] which results in decreased susceptibility to Sarin | decreases activity|decreases response to substance | 16914529 |
| D005702 | Galantamine | [Galantamine results in decreased activity of ACHE protein] which results in decreased susceptibility to Soman | decreases activity|decreases response to substance | 16914529 |
| D005702 | Galantamine | Galantamine results in decreased activity of ACHE protein | decreases activity | 14535624 |
| D005702 | Galantamine | Galantamine binds to and results in decreased activity of ACHE protein | affects binding|decreases activity | 19596285 |
| C014022 | heptenophos | heptenophos results in decreased activity of ACHE protein | decreases activity | 8783813 |
| C014022 | heptenophos | HI 6 inhibits the reaction [heptenophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C014022 | heptenophos | HLo 7 inhibits the reaction [heptenophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C014022 | heptenophos | Obidoxime Chloride inhibits the reaction [heptenophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C014022 | heptenophos | pralidoxime inhibits the reaction [heptenophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C022870 | HI 6 | HI 6 inhibits the reaction [methamidophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 3240095 |
| C022870 | HI 6 | HI 6 inhibits the reaction [acephate results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 10681099 |
| C022870 | HI 6 | HI 6 inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 10681099 |
| C022870 | HI 6 | HI 6 inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C022870 | HI 6 | HI 6 inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C022870 | HI 6 | HI 6 inhibits the reaction [dicrotophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C022870 | HI 6 | HI 6 inhibits the reaction [dimethoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C022870 | HI 6 | HI 6 inhibits the reaction [heptenophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C022870 | HI 6 | HI 6 inhibits the reaction [malaoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C022870 | HI 6 | HI 6 inhibits the reaction [methamidophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 18804659 8783813 |
| C022870 | HI 6 | HI 6 inhibits the reaction [methyl demeton results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C022870 | HI 6 | HI 6 inhibits the reaction [Mevinphos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C022870 | HI 6 | HI 6 inhibits the reaction [Monocrotophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C022870 | HI 6 | HI 6 inhibits the reaction [Paraoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C022870 | HI 6 | HI 6 inhibits the reaction [Phosphamidon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C022870 | HI 6 | HI 6 inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C022870 | HI 6 | HI 6 binds to and results in decreased activity of ACHE protein | affects binding|decreases activity | 16598855 |
| C058577 | HLo 7 | HLo 7 inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C058577 | HLo 7 | HLo 7 inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C058577 | HLo 7 | HLo 7 inhibits the reaction [dicrotophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C058577 | HLo 7 | HLo 7 inhibits the reaction [dimethoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C058577 | HLo 7 | HLo 7 inhibits the reaction [heptenophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C058577 | HLo 7 | HLo 7 inhibits the reaction [malaoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C058577 | HLo 7 | HLo 7 inhibits the reaction [methamidophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C058577 | HLo 7 | HLo 7 inhibits the reaction [methyl demeton results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C058577 | HLo 7 | HLo 7 inhibits the reaction [Mevinphos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C058577 | HLo 7 | HLo 7 inhibits the reaction [Monocrotophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C058577 | HLo 7 | HLo 7 inhibits the reaction [Paraoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C058577 | HLo 7 | HLo 7 inhibits the reaction [Phosphamidon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C058577 | HLo 7 | HLo 7 inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C050426 | huperzine A | huperzine A results in decreased activity of ACHE protein | decreases activity | 15652380 |
| C050426 | huperzine A | huperzine A results in decreased activity of ACHE protein | decreases activity | 16914529 15956816 |
| D006997 | Hypochlorous Acid | [Hypochlorous Acid co-treated with Sodium Nitrite] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 12414318 |
| D006997 | Hypochlorous Acid | Hypochlorous Acid results in decreased activity of ACHE protein | decreases activity | 12414318 |
| D007306 | Insecticides | ACHE protein results in decreased susceptibility to Insecticides | decreases response to substance | 7514668 |
| D007531 | Isoflurophate | Isoflurophate results in decreased activity of ACHE protein | decreases activity | 17615116 |
| D007531 | Isoflurophate | Isoflurophate results in decreased activity of ACHE protein | decreases activity | 1909249 |
| D007531 | Isoflurophate | Isoflurophate binds to and results in increased phosphorylation of and results in decreased activity of ACHE protein | affects binding|decreases activity|increases phosphorylation | 17402711 |
| D007531 | Isoflurophate | Isoflurophate results in decreased activity of ACHE protein modified form | decreases activity | 10473783 |
| D007531 | Isoflurophate | pralidoxime inhibits the reaction [Isoflurophate results in decreased activity of ACHE protein modified form] | decreases activity|decreases reaction | 10473783 |
| C018326 | isomalathion | isomalathion results in decreased activity of ACHE protein | decreases activity | 8448346 |
| D007854 | Lead | Aluminum promotes the reaction [Lead results in decreased activity of ACHE protein] | decreases activity|increases reaction | 15266904 |
| D007854 | Lead | Lead results in decreased activity of ACHE protein | decreases activity | 15266904 |
| D001556 | Lindane | Lindane results in decreased activity of ACHE protein | decreases activity | 16257038 |
| C039294 | linoleylanilide | linoleylanilide results in increased activity of ACHE protein | increases activity | 2238437 |
| C419729 | macluraxanthone C | macluraxanthone C binds to and results in decreased activity of ACHE protein | affects binding|decreases activity | 19596285 |
| C005095 | malachite green | malachite green results in decreased activity of ACHE protein | decreases activity | 18571634 |
| C100082 | malaoxon | malaoxon results in decreased activity of ACHE protein | decreases activity | 17615116 |
| C100082 | malaoxon | malaoxon results in decreased activity of ACHE protein | decreases activity | 18625398 |
| C100082 | malaoxon | ACHE protein affects the susceptibility to malaoxon | affects response to substance | 8016090 |
| C100082 | malaoxon | ACHE protein mutant form results in decreased susceptibility to malaoxon | decreases response to substance | 8016090 |
| C100082 | malaoxon | HI 6 inhibits the reaction [malaoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C100082 | malaoxon | HLo 7 inhibits the reaction [malaoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C100082 | malaoxon | malaoxon results in decreased activity of ACHE protein | decreases activity | 8783813 |
| C100082 | malaoxon | Obidoxime Chloride inhibits the reaction [malaoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C100082 | malaoxon | pralidoxime inhibits the reaction [malaoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D008294 | Malathion | Malathion results in decreased activity of ACHE protein | decreases activity | 17364237 |
| D008294 | Malathion | ACHE gene results in decreased susceptibility to Malathion | decreases response to substance | 18625398 |
| D008294 | Malathion | Malathion results in decreased activity of ACHE protein | decreases activity | 11534899 |
| D008294 | Malathion | Malathion results in decreased activity of ACHE protein | decreases activity | 15683842 |
| D008294 | Malathion | Malathion results in decreased activity of ACHE protein | decreases activity | 17590326 |
| D008294 | Malathion | [Endosulfan co-treated with Malathion] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 2380476 |
| D008294 | Malathion | [Malathion co-treated with Permethrin] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 14713564 |
| D008294 | Malathion | [Malathion co-treated with Permethrin] results in increased activity of ACHE protein | affects cotreatment|increases activity | 14713564 |
| D008294 | Malathion | Malathion results in decreased activity of ACHE protein | decreases activity | 19784758 |
| C013099 | mancozeb | mancozeb results in increased activity of ACHE protein | increases activity | 15261450 |
| C013099 | mancozeb | [propamocarb co-treated with mancozeb] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 18585479 |
| C013099 | mancozeb | mancozeb affects the activity of ACHE protein | affects activity | 10641187 |
| D008344 | Maneb | Maneb results in decreased expression of ACHE protein | decreases expression | 3868355 |
| C013592 | mangiferin | mangiferin results in decreased activity of ACHE protein | decreases activity | 19182383 |
| C014655 | methamidophos | methamidophos results in decreased activity of ACHE protein | decreases activity | 12210959 |
| C014655 | methamidophos | methamidophos binds to and results in increased phosphorylation of and results in decreased activity of ACHE protein | affects binding|decreases activity|increases phosphorylation | 2097819 |
| C014655 | methamidophos | methamidophos analog results in decreased activity of ACHE protein | decreases activity | 17032020 |
| C014655 | methamidophos | methamidophos results in decreased activity of ACHE protein | decreases activity | 15522598 |
| C014655 | methamidophos | methamidophos results in decreased activity of ACHE protein | decreases activity | 18569613 |
| C014655 | methamidophos | methamidophos results in decreased activity of ACHE protein | decreases activity | 17533655 |
| C014655 | methamidophos | methamidophos results in decreased activity of ACHE protein | decreases activity | 17533655 |
| C014655 | methamidophos | methamidophos results in decreased activity of ACHE protein | decreases activity | 15522598 |
| C014655 | methamidophos | methamidophos results in decreased activity of ACHE protein mutant form | decreases activity | 15522598 |
| C014655 | methamidophos | HI 6 inhibits the reaction [methamidophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 3240095 |
| C014655 | methamidophos | methamidophos analog results in decreased activity of ACHE protein | decreases activity | 17032020 |
| C014655 | methamidophos | methamidophos results in decreased activity of ACHE protein | decreases activity | 3240095 15522598 7059283 |
| C014655 | methamidophos | Obidoxime Chloride inhibits the reaction [methamidophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 3240095 7059283 |
| C014655 | methamidophos | trimethylene-bis(4-hydroxyiminomethylpyridinium) inhibits the reaction [methamidophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 7059283 |
| C014655 | methamidophos | methamidophos analog results in decreased activity of ACHE protein | decreases activity | 7654138 |
| C014655 | methamidophos | methamidophos results in decreased activity of ACHE protein | decreases activity | 1781739 2238437 |
| C014655 | methamidophos | HI 6 inhibits the reaction [methamidophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 18804659 |
| C014655 | methamidophos | HLo 7 inhibits the reaction [methamidophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C014655 | methamidophos | methamidophos binds to and results in increased phosphorylation of ACHE protein | affects binding|increases phosphorylation | 11453739 |
| C014655 | methamidophos | [methamidophos co-treated with decamethrin] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 12191869 |
| C014655 | methamidophos | methamidophos results in decreased activity of ACHE protein | decreases activity | 18804659 12191869 8783813 15522598 17382909 1781739 |
| C014655 | methamidophos | Obidoxime Chloride inhibits the reaction [methamidophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C014655 | methamidophos | pralidoxime inhibits the reaction [methamidophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 18804659 8783813 |
| C014655 | methamidophos | methamidophos results in decreased activity of ACHE protein | decreases activity | 16249032 |
| C014655 | methamidophos | methamidophos binds to and results in increased phosphorylation of and results in decreased activity of ACHE protein | affects binding|decreases activity|increases phosphorylation | 17402711 |
| C014655 | methamidophos | methamidophos inhibits the reaction [acephate results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 9074804 |
| C014655 | methamidophos | methamidophos binds to and results in increased phosphorylation of and results in decreased activity of ACHE protein | affects binding|decreases activity|increases phosphorylation | 2097819 |
| C014655 | methamidophos | methamidophos results in decreased activity of ACHE protein | decreases activity | 16119251 11048668 12039681 |
| C014655 | methamidophos | methamidophos binds to and results in increased phosphorylation of ACHE protein | affects binding|increases phosphorylation | 11453739 |
| C014655 | methamidophos | acephate inhibits the reaction [methamidophos binds to and results in decreased activity of ACHE protein] | affects binding|decreases activity|decreases reaction | 3798464 |
| C014655 | methamidophos | methamidophos binds to and results in decreased activity of ACHE protein | affects binding|decreases activity | 3798464 |
| C014655 | methamidophos | methamidophos binds to and results in increased phosphorylation of and results in decreased activity of ACHE protein | affects binding|decreases activity|increases phosphorylation | 4060156 9568380 |
| C014655 | methamidophos | methamidophos results in decreased activity of ACHE protein | decreases activity | 18290547 |
| D000432 | Methanol | Methanol results in decreased activity of ACHE protein | decreases activity | 17673349 17580119 |
| D000432 | Methanol | Methanol results in decreased activity of ACHE protein | decreases activity | 16129618 |
| D000432 | Methanol | Methanol results in decreased activity of ACHE protein | decreases activity | 17673349 17580119 |
| D008724 | Methomyl | Methomyl results in decreased activity of ACHE protein | decreases activity | 9890446 9442915 |
| D008724 | Methomyl | Methomyl results in decreased activity of ACHE protein | decreases activity | 16461013 |
| D008724 | Methomyl | Methomyl results in decreased activity of ACHE protein | decreases activity | 1909249 |
| D008724 | Methomyl | Methomyl results in decreased activity of ACHE protein | decreases activity | 8134223 |
| D008724 | Methomyl | ACHE protein polymorphism results in decreased susceptibility to Methomyl | decreases response to substance | 2904862 |
| D008724 | Methomyl | ACHE protein polymorphism results in decreased susceptibility to Methomyl | decreases response to substance | 11332849 |
| D008724 | Methomyl | ACHE protein affects the susceptibility to Methomyl | affects response to substance | 11886776 |
| C026086 | methyl demeton | HI 6 inhibits the reaction [methyl demeton results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C026086 | methyl demeton | HLo 7 inhibits the reaction [methyl demeton results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C026086 | methyl demeton | methyl demeton results in decreased activity of ACHE protein | decreases activity | 8783813 |
| C026086 | methyl demeton | Obidoxime Chloride inhibits the reaction [methyl demeton results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C026086 | methyl demeton | pralidoxime inhibits the reaction [methyl demeton results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D008739 | Methyl Green | Methyl Green results in decreased activity of ACHE protein | decreases activity | 18571634 |
| C008480 | methylparaoxon | methylparaoxon results in decreased activity of ACHE protein | decreases activity | 18804659 |
| C008480 | methylparaoxon | methylparaoxon results in decreased activity of ACHE protein | decreases activity | 18761328 12478623 |
| C008480 | methylparaoxon | methylparaoxon results in decreased activity of ACHE protein | decreases activity | 10871426 |
| D008743 | Methyl Parathion | Methyl Parathion results in decreased activity of ACHE protein | decreases activity | 15147928 |
| D008743 | Methyl Parathion | Methyl Parathion results in decreased activity of ACHE protein | decreases activity | 2511899 1586462 |
| D008743 | Methyl Parathion | Methyl Parathion results in decreased activity of ACHE protein | decreases activity | 11534899 |
| D008743 | Methyl Parathion | Methyl Parathion results in decreased activity of ACHE protein | decreases activity | 8561923 |
| D008743 | Methyl Parathion | Methyl Parathion results in decreased activity of ACHE protein | decreases activity | 15889724 |
| D008743 | Methyl Parathion | Methyl Parathion results in decreased activity of ACHE protein | decreases activity | 3868356 |
| D008743 | Methyl Parathion | [Methyl Parathion co-treated with decamethrin] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 12191869 |
| D008743 | Methyl Parathion | [Methyl Parathion co-treated with Parathion] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 1512808 |
| D008743 | Methyl Parathion | Methyl Parathion results in decreased activity of ACHE protein | decreases activity | 16766477 12191869 |
| D008743 | Methyl Parathion | [Atrazine co-treated with Methyl Parathion] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 12109753 |
| D008743 | Methyl Parathion | Methyl Parathion results in decreased activity of ACHE protein | decreases activity | 15978292 |
| D008743 | Methyl Parathion | Methyl Parathion results in decreased activity of ACHE protein | decreases activity | 8854969 |
| D008743 | Methyl Parathion | Methyl Parathion results in decreased activity of ACHE protein | decreases activity | 1801511 |
| D008743 | Methyl Parathion | Methyl Parathion results in decreased activity of ACHE protein | decreases activity | 9588345 |
| D008743 | Methyl Parathion | Methyl Parathion results in decreased activity of ACHE protein | decreases activity | 6485009 |
| D008743 | Methyl Parathion | Methyl Parathion results in decreased activity of ACHE protein | decreases activity | 10473783 |
| D008743 | Methyl Parathion | pralidoxime inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 10473783 |
| D008743 | Methyl Parathion | Atropine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 2241428 |
| D008743 | Methyl Parathion | CYP2B1 protein affects the reaction [Methyl Parathion results in decreased activity of ACHE protein] | affects reaction|decreases activity | 11684353 |
| D008743 | Methyl Parathion | CYP2B2 protein affects the reaction [Methyl Parathion results in decreased activity of ACHE protein] | affects reaction|decreases activity | 11684353 |
| D008743 | Methyl Parathion | Memantine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 2241428 |
| D008743 | Methyl Parathion | [Methyl Parathion co-treated with Chlorpyrifos] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 11405414 |
| D008743 | Methyl Parathion | [Methyl Parathion co-treated with NADP] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 11684353 |
| D008743 | Methyl Parathion | [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of ACHE protein | affects cotreatment|decreases expression | 17963125 |
| D008743 | Methyl Parathion | [Methyl Parathion co-treated with pralidoxime] results in decreased expression of ACHE protein | affects cotreatment|decreases expression | 17963125 |
| D008743 | Methyl Parathion | Methyl Parathion results in decreased activity of ACHE protein | decreases activity | 15591769 14746346 7322183 11481665 7966439 19784758 1455421 2241428 14514956 11405414 3975908 6483827 12478623 11495289 15342957 10918524 16645783 |
| D008743 | Methyl Parathion | Phenobarbital inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 11684353 |
| D008743 | Methyl Parathion | ACHE protein affects the susceptibility to Methyl Parathion | affects response to substance | 11886776 |
| D008787 | Metoclopramide | Metoclopramide inhibits the reaction [mipafox results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16193528 |
| D008787 | Metoclopramide | Metoclopramide inhibits the reaction [Paraoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16193528 |
| D008799 | Mevinphos | Mevinphos results in decreased activity of ACHE protein | decreases activity | 18569613 |
| D008799 | Mevinphos | HI 6 inhibits the reaction [Mevinphos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D008799 | Mevinphos | HLo 7 inhibits the reaction [Mevinphos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D008799 | Mevinphos | Mevinphos results in decreased activity of ACHE protein | decreases activity | 8783813 |
| D008799 | Mevinphos | Obidoxime Chloride inhibits the reaction [Mevinphos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D008799 | Mevinphos | pralidoxime inhibits the reaction [Mevinphos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C005238 | mipafox | Metoclopramide inhibits the reaction [mipafox results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16193528 |
| C005238 | mipafox | mipafox results in decreased activity of ACHE protein | decreases activity | 16766477 |
| D008999 | Monocrotophos | Monocrotophos results in decreased activity of ACHE protein | decreases activity | 18569613 |
| D008999 | Monocrotophos | Monocrotophos results in decreased activity of ACHE protein | decreases activity | 17590326 |
| D008999 | Monocrotophos | HI 6 inhibits the reaction [Monocrotophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D008999 | Monocrotophos | HLo 7 inhibits the reaction [Monocrotophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D008999 | Monocrotophos | Monocrotophos results in decreased activity of ACHE protein | decreases activity | 8783813 |
| D008999 | Monocrotophos | Obidoxime Chloride inhibits the reaction [Monocrotophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D008999 | Monocrotophos | pralidoxime inhibits the reaction [Monocrotophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D009151 | Mustard Gas | Mustard Gas results in increased activity of ACHE protein | increases activity | 17229443 |
| D009151 | Mustard Gas | Mustard Gas results in increased expression of ACHE protein | increases expression | 17229443 |
| C048599 | N(6)-cyclopentyladenosine | N(6)-cyclopentyladenosine inhibits the reaction [Sarin results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 12415428 |
| D009388 | Neostigmine | Neostigmine results in decreased activity of ACHE protein | decreases activity | 15683842 |
| D009388 | Neostigmine | Neostigmine results in decreased activity of ACHE protein | decreases activity | 1909249 |
| D009532 | Nickel | Nickel results in decreased expression of ACHE mRNA | decreases expression | 18812211 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride inhibits the reaction [methamidophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 7059283 3240095 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride inhibits the reaction [dicrotophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride inhibits the reaction [dimethoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride inhibits the reaction [ethylparaoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 18804659 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride inhibits the reaction [heptenophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride inhibits the reaction [malaoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride inhibits the reaction [methamidophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride inhibits the reaction [methyl demeton results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride inhibits the reaction [Mevinphos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride inhibits the reaction [Monocrotophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride inhibits the reaction [Paraoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 8134223 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride inhibits the reaction [Phosphamidon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride inhibits the reaction [tabun analog results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 17382909 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D009768 | Obidoxime Chloride | Obidoxime Chloride metabolite results in decreased activity of ACHE protein | decreases activity | 15876422 |
| C038731 | oleoylanilide | oleoylanilide results in increased activity of ACHE protein | increases activity | 2238437 |
| C009618 | O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate | O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in decreased activity of ACHE protein | decreases activity | 17615116 |
| C009618 | O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate | O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in decreased expression of ACHE protein | decreases expression | 16085276 |
| C009618 | O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate | pralidoxime inhibits the reaction [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in decreased expression of ACHE protein] | decreases expression|decreases reaction | 16085276 |
| C009618 | O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate | O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in increased expression of ACHE mRNA alternative form | increases expression | 17366821 |
| D009943 | Organophosphorus Compounds | Organophosphorus Compounds results in decreased activity of ACHE protein | decreases activity | 17098105 |
| D009943 | Organophosphorus Compounds | Atropine inhibits the reaction [Organophosphorus Compounds results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16293236 |
| D009943 | Organophosphorus Compounds | Pyridostigmine Bromide inhibits the reaction [Organophosphorus Compounds results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16293236 |
| C011960 | oxamyl | oxamyl results in decreased activity of ACHE protein | decreases activity | 10871426 |
| D010261 | Paraoxon | ACHE protein mutant form results in decreased susceptibility to Paraoxon | decreases response to substance | 9371089 |
| D010261 | Paraoxon | [Galantamine results in decreased activity of ACHE protein] which results in decreased susceptibility to Paraoxon | decreases activity|decreases response to substance | 16914529 |
| D010261 | Paraoxon | Paraoxon results in decreased activity of ACHE protein | decreases activity | 17158603 |
| D010261 | Paraoxon | Paraoxon results in decreased activity of ACHE protein | decreases activity | 15683842 |
| D010261 | Paraoxon | ACHE protein affects the susceptibility to Paraoxon | affects response to substance | 8016090 |
| D010261 | Paraoxon | ACHE protein mutant form results in decreased susceptibility to Paraoxon | decreases response to substance | 8016090 |
| D010261 | Paraoxon | Paraoxon results in decreased activity of ACHE protein | decreases activity | 1909249 |
| D010261 | Paraoxon | HI 6 inhibits the reaction [Paraoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D010261 | Paraoxon | HLo 7 inhibits the reaction [Paraoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D010261 | Paraoxon | Metoclopramide inhibits the reaction [Paraoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16193528 |
| D010261 | Paraoxon | Obidoxime Chloride inhibits the reaction [Paraoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 8134223 |
| D010261 | Paraoxon | Paraoxon results in decreased activity of ACHE protein | decreases activity | 16766477 15876422 8783813 8134223 |
| D010261 | Paraoxon | pralidoxime inhibits the reaction [Paraoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8134223 8783813 |
| D010261 | Paraoxon | Ranitidine inhibits the reaction [Paraoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16193528 |
| D010261 | Paraoxon | Tiapride inhibits the reaction [Paraoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16193528 |
| D010261 | Paraoxon | Paraoxon results in increased phosphorylation of and results in decreased activity of ACHE protein | decreases activity|increases phosphorylation | 12974645 |
| D010261 | Paraoxon | Paraoxon results in decreased activity of ACHE protein modified form | decreases activity | 10473783 |
| D010261 | Paraoxon | pralidoxime inhibits the reaction [Paraoxon results in decreased activity of ACHE protein modified form] | decreases activity|decreases reaction | 10473783 |
| D010261 | Paraoxon | Paraoxon results in decreased activity of ACHE protein | decreases activity | 12629810 |
| D010261 | Paraoxon | Paraoxon binds to ACHE protein | affects binding | 11453739 |
| D010269 | Paraquat | Paraquat results in decreased activity of ACHE protein | decreases activity | 17364237 |
| D010269 | Paraquat | Paraquat results in decreased activity of ACHE protein | decreases activity | 11281253 |
| C005409 | pararosaniline | pararosaniline results in decreased activity of ACHE protein | decreases activity | 18571634 |
| D010278 | Parathion | Parathion results in decreased activity of ACHE protein | decreases activity | 15041264 |
| D010278 | Parathion | Parathion results in decreased activity of ACHE protein | decreases activity | 17158603 |
| D010278 | Parathion | Parathion results in decreased activity of ACHE protein | decreases activity | 15683842 |
| D010278 | Parathion | Parathion results in decreased activity of ACHE protein | decreases activity | 12878415 |
| D010278 | Parathion | Parathion results in decreased activity of ACHE protein | decreases activity | 12959529 |
| D010278 | Parathion | Parathion results in decreased activity of ACHE protein | decreases activity | 15889724 |
| D010278 | Parathion | Parathion results in decreased activity of ACHE protein | decreases activity | 10681099 |
| D010278 | Parathion | [Methyl Parathion co-treated with Parathion] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 1512808 |
| D010278 | Parathion | Parathion results in decreased activity of ACHE protein | decreases activity | 10473783 |
| D010278 | Parathion | pralidoxime inhibits the reaction [Parathion results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 10473783 |
| D010278 | Parathion | Parathion results in decreased activity of ACHE protein | decreases activity | 10581123 |
| D010278 | Parathion | Parathion results in decreased activity of ACHE protein | decreases activity | 15342957 19784758 |
| D026023 | Permethrin | Permethrin results in decreased activity of ACHE protein | decreases activity | 1459649 |
| D026023 | Permethrin | [DEET co-treated with Permethrin] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 11248143 14713564 |
| D026023 | Permethrin | [DEET co-treated with Permethrin] results in increased activity of ACHE protein | affects cotreatment|increases activity | 14713564 |
| D026023 | Permethrin | [Malathion co-treated with Permethrin] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 14713564 |
| D026023 | Permethrin | [Malathion co-treated with Permethrin] results in increased activity of ACHE protein | affects cotreatment|increases activity | 14713564 |
| D026023 | Permethrin | Permethrin results in decreased activity of ACHE protein | decreases activity | 7595515 |
| D026023 | Permethrin | Permethrin results in increased activity of ACHE protein | increases activity | 11248143 14713564 |
| D026023 | Permethrin | [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 14751452 11248143 |
| D026023 | Permethrin | [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in increased activity of ACHE protein | affects cotreatment|increases activity | 14751452 |
| D026023 | Permethrin | [Pyridostigmine Bromide co-treated with Permethrin] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 11248143 |
| D026023 | Permethrin | [Pyridostigmine Bromide co-treated with Permethrin] results in increased activity of ACHE protein | affects cotreatment|increases activity | 14751452 |
| D010575 | Pesticides | Pesticides results in decreased activity of ACHE protein | decreases activity | 15922524 |
| D010634 | Phenobarbital | Phenobarbital affects the activity of ACHE protein | affects activity | 12959529 |
| D010634 | Phenobarbital | Phenobarbital inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 11684353 |
| C008838 | phenthoate | phenthoate results in decreased activity of ACHE protein | decreases activity | 15683842 |
| D010672 | Phenytoin | Phenytoin results in increased activity of ACHE protein | increases activity | 16946593 |
| D010706 | Phosmet | Phosmet results in decreased activity of ACHE protein | decreases activity | 10509429 |
| D010707 | Phosphamidon | Phosphamidon results in decreased activity of ACHE protein | decreases activity | 18569613 |
| D010707 | Phosphamidon | Phosphamidon results in decreased activity of ACHE protein | decreases activity | 10509429 |
| D010707 | Phosphamidon | HI 6 inhibits the reaction [Phosphamidon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D010707 | Phosphamidon | HLo 7 inhibits the reaction [Phosphamidon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D010707 | Phosphamidon | Obidoxime Chloride inhibits the reaction [Phosphamidon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D010707 | Phosphamidon | Phosphamidon results in decreased activity of ACHE protein | decreases activity | 8783813 |
| D010707 | Phosphamidon | pralidoxime inhibits the reaction [Phosphamidon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D010707 | Phosphamidon | Phosphamidon results in decreased activity of ACHE protein | decreases activity | 1833318 |
| D010755 | Phosphoric Acid Esters | Phosphoric Acid Esters results in decreased activity of ACHE protein | decreases activity | 16872049 |
| D010830 | Physostigmine | Physostigmine analog inhibits the reaction [ACHE protein results in increased metabolism of Acetylthiocholine] | decreases reaction|increases metabolic processing | 18433895 |
| D010830 | Physostigmine | Physostigmine analog results in decreased activity of ACHE protein | decreases activity | 18433895 |
| D010830 | Physostigmine | Albuterol promotes the reaction [Physostigmine results in increased secretion of ACHE protein] | increases reaction|increases secretion | 17158603 |
| D010830 | Physostigmine | Physostigmine results in decreased activity of ACHE protein | decreases activity | 17158603 |
| D010830 | Physostigmine | Physostigmine results in increased secretion of ACHE protein | increases secretion | 17158603 |
| D010830 | Physostigmine | Physostigmine results in decreased activity of ACHE protein | decreases activity | 15683842 |
| D010830 | Physostigmine | Physostigmine results in decreased activity of ACHE protein | decreases activity | 14644616 |
| D010830 | Physostigmine | Physostigmine results in decreased activity of ACHE protein | decreases activity | 15811534 |
| D010830 | Physostigmine | Physostigmine results in decreased activity of ACHE protein | decreases activity | 15811534 |
| D010830 | Physostigmine | Physostigmine results in decreased activity of ACHE protein | decreases activity | 15811534 |
| C032727 | piperidine | piperidine analog inhibits the reaction [ACHE protein promotes the reaction [APP protein binds to APP protein]] | affects binding|decreases reaction|increases reaction | 17681794 |
| C032727 | piperidine | piperidine analog results in decreased activity of ACHE protein | decreases activity | 17681794 |
| D010889 | Piracetam | Piracetam results in decreased activity of ACHE protein | decreases activity | 16946593 |
| C011994 | pirimicarb | ACHE protein affects the susceptibility to pirimicarb | affects response to substance | 10333576 |
| C011994 | pirimicarb | pirimicarb results in decreased activity of ACHE protein | decreases activity | 12210959 |
| C014153 | pirimiphos methyl | ACHE protein affects the susceptibility to pirimiphos methyl | affects response to substance | 17710279 |
| C014153 | pirimiphos methyl | pirimiphos methyl results in decreased activity of ACHE protein | decreases activity | 8658539 |
| C014153 | pirimiphos methyl | pirimiphos methyl results in decreased activity of ACHE protein mutant form | decreases activity | 16159111 |
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ACHE mRNA | affects binding|decreases expression|increases activity | 19710929 |
| D010936 | Plant Extracts | Plant Extracts results in decreased activity of ACHE protein | decreases activity | 16822217 |
| D010936 | Plant Extracts | Plant Extracts results in decreased activity of ACHE protein | decreases activity | 17168769 |
| D011078 | Polychlorinated Biphenyls | Polychlorinated Biphenyls results in decreased activity of ACHE protein | decreases activity | 17097718 |
| D011078 | Polychlorinated Biphenyls | Polychlorinated Biphenyls results in decreased activity of ACHE protein | decreases activity | 17289233 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in decreased expression of ACHE protein] | decreases expression|decreases reaction | 16085276 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [acephate results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 10681099 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 10681099 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [dicrotophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [Dimethoate results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16112538 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [dimethoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [heptenophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [malaoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [methamidophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 18804659 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [methyl demeton results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [Mevinphos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [Monocrotophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [Paraoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8134223 8783813 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [Phosphamidon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| C028797 | pralidoxime | pralidoxime binds to and results in decreased activity of ACHE protein | affects binding|decreases activity | 16598855 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein modified form] | decreases activity|decreases reaction | 10473783 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [Isoflurophate results in decreased activity of ACHE protein modified form] | decreases activity|decreases reaction | 10473783 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 10473783 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [Paraoxon results in decreased activity of ACHE protein modified form] | decreases activity|decreases reaction | 10473783 |
| C028797 | pralidoxime | pralidoxime inhibits the reaction [Parathion results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 10473783 |
| C028797 | pralidoxime | [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of ACHE protein | affects cotreatment|decreases expression | 17963125 |
| C028797 | pralidoxime | [Methyl Parathion co-treated with pralidoxime] results in decreased expression of ACHE protein | affects cotreatment|decreases expression | 17963125 |
| C033205 | propamocarb | [propamocarb co-treated with mancozeb] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 18585479 |
| D001074 | Propoxur | ACHE protein mutant form results in decreased susceptibility to Propoxur | decreases response to substance | 9371089 |
| D001074 | Propoxur | ACHE protein affects the susceptibility to Propoxur | affects response to substance | 10333576 |
| D001074 | Propoxur | Propoxur results in decreased activity of ACHE protein | decreases activity | 11129708 |
| D001074 | Propoxur | ACHE protein affects the susceptibility to Propoxur | affects response to substance | 8016090 |
| D001074 | Propoxur | ACHE protein mutant form results in decreased susceptibility to Propoxur | decreases response to substance | 8016090 |
| D001074 | Propoxur | Propoxur results in decreased activity of ACHE protein | decreases activity | 14644616 |
| D011729 | Pyridostigmine Bromide | Pyridostigmine Bromide results in decreased activity of ACHE protein | decreases activity | 15683842 |
| D011729 | Pyridostigmine Bromide | [Pyridostigmine Bromide co-treated with DEET] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 11248143 |
| D011729 | Pyridostigmine Bromide | [Pyridostigmine Bromide co-treated with DEET] results in increased activity of ACHE protein | affects cotreatment|increases activity | 14751452 |
| D011729 | Pyridostigmine Bromide | [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 14751452 11248143 |
| D011729 | Pyridostigmine Bromide | [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in increased activity of ACHE protein | affects cotreatment|increases activity | 14751452 |
| D011729 | Pyridostigmine Bromide | [Pyridostigmine Bromide co-treated with Permethrin] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 11248143 |
| D011729 | Pyridostigmine Bromide | [Pyridostigmine Bromide co-treated with Permethrin] results in increased activity of ACHE protein | affects cotreatment|increases activity | 14751452 |
| D011729 | Pyridostigmine Bromide | Pyridostigmine Bromide results in decreased activity of ACHE protein | decreases activity | 11248143 |
| D011729 | Pyridostigmine Bromide | Pyridostigmine Bromide inhibits the reaction [Organophosphorus Compounds results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16293236 |
| D011729 | Pyridostigmine Bromide | Pyridostigmine Bromide results in decreased activity of ACHE protein | decreases activity | 16914529 |
| D011794 | Quercetin | Quercetin binds to and results in decreased activity of ACHE protein | affects binding|decreases activity | 19596285 |
| D011899 | Ranitidine | Ranitidine inhibits the reaction [Paraoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16193528 |
| C072506 | rivastigmine | AFDX 384 affects the reaction [rivastigmine affects the activity of ACHE protein] | affects activity|affects reaction | 12111444 |
| C072506 | rivastigmine | rivastigmine affects the activity of ACHE protein | affects activity | 12111444 |
| C072506 | rivastigmine | rivastigmine results in increased carbamoylation of and results in decreased activity of ACHE protein | decreases activity|increases carbamoylation | 20557099 |
| D012524 | Sarin | [Galantamine results in decreased activity of ACHE protein] which results in decreased susceptibility to Sarin | decreases activity|decreases response to substance | 16914529 |
| D012524 | Sarin | Sarin results in decreased activity of ACHE protein | decreases activity | 15888665 |
| D012524 | Sarin | Sarin binds to and results in increased phosphorylation of and results in decreased activity of ACHE protein | affects binding|decreases activity|increases phosphorylation | 17402711 |
| D012524 | Sarin | N(6)-cyclopentyladenosine inhibits the reaction [Sarin results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 12415428 |
| D012524 | Sarin | Sarin results in decreased activity of ACHE protein | decreases activity | 12415428 |
| D012524 | Sarin | Sarin results in decreased activity of ACHE protein | decreases activity | 16914529 |
| D012643 | Selenium | Selenium inhibits the reaction [arsenic trioxide results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16916622 |
| C017947 | sodium arsenite | sodium arsenite results in increased activity of ACHE protein | increases activity | 20376865 |
| D012977 | Sodium Nitrite | [Hypochlorous Acid co-treated with Sodium Nitrite] results in decreased activity of ACHE protein | affects cotreatment|decreases activity | 12414318 |
| D018038 | Sodium Selenite | Sodium Selenite results in increased expression of ACHE mRNA | increases expression | 16542727 |
| D012999 | Soman | [Galantamine results in decreased activity of ACHE protein] which results in decreased susceptibility to Soman | decreases activity|decreases response to substance | 16914529 |
| D012999 | Soman | Soman results in decreased activity of ACHE protein | decreases activity | 16914529 |
| C009374 | tabun | tabun results in decreased activity of ACHE protein | decreases activity | 7059283 |
| C009374 | tabun | Obidoxime Chloride inhibits the reaction [tabun analog results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 17382909 |
| C009374 | tabun | tabun analog results in decreased activity of ACHE protein | decreases activity | 17382909 |
| C009374 | tabun | tabun binds to and results in increased phosphorylation of ACHE protein | affects binding|increases phosphorylation | 11453739 |
| C009374 | tabun | tabun results in decreased activity of ACHE protein | decreases activity | 17382909 |
| C009374 | tabun | tabun binds to and results in increased phosphorylation of ACHE protein | affects binding|increases phosphorylation | 11453739 |
| C009374 | tabun | tabun results in decreased activity of ACHE protein | decreases activity | 16914529 |
| C099872 | TAK 147 | TAK 147 results in decreased activity of ACHE protein | decreases activity | 14535624 |
| C087926 | tellimagrandin I | tellimagrandin I results in decreased activity of ACHE protein | decreases activity | 14757314 |
| C037565 | terbutylazine | [Chlorpyrifos co-treated with terbutylazine] results in decreased expression of ACHE protein | affects cotreatment|decreases expression | 16085276 |
| C027971 | thiodicarb | thiodicarb results in decreased activity of ACHE protein | decreases activity | 16461013 |
| D013976 | Tiapride | Tiapride binds to ACHE protein | affects binding | 16193528 |
| D013976 | Tiapride | Tiapride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16036766 16193528 |
| D013976 | Tiapride | Tiapride inhibits the reaction [Paraoxon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 16193528 |
| C543146 | timosaponin AIII | timosaponin AIII results in decreased activity of ACHE protein | decreases activity | 19426756 |
| D014112 | Toxaphene | Toxaphene results in decreased activity of ACHE protein | decreases activity | 8262581 |
| D014212 | Tretinoin | Tretinoin results in increased secretion of ACHE protein | increases secretion | 16188934 |
| D014236 | Trichlorfon | Trichlorfon results in decreased activity of ACHE protein | decreases activity | 18569613 |
| D014236 | Trichlorfon | HI 6 inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 10681099 |
| D014236 | Trichlorfon | pralidoxime inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 10681099 |
| D014236 | Trichlorfon | Trichlorfon results in decreased activity of ACHE protein | decreases activity | 10681099 10509429 |
| D014236 | Trichlorfon | Trimedoxime inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 10681099 |
| D014236 | Trichlorfon | HI 6 inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D014236 | Trichlorfon | HLo 7 inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D014236 | Trichlorfon | Obidoxime Chloride inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D014236 | Trichlorfon | pralidoxime inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 8783813 |
| D014236 | Trichlorfon | Trichlorfon results in decreased activity of ACHE protein | decreases activity | 18804659 19631781 10718203 15386949 11526466 15569517 10791297 8783813 |
| D014236 | Trichlorfon | ACHE protein mutant form results in decreased susceptibility to Trichlorfon | decreases response to substance | 12803484 |
| D014236 | Trichlorfon | Trichlorfon results in decreased activity of ACHE protein | decreases activity | 12803484 |
| D014236 | Trichlorfon | Trichlorfon results in decreased activity of ACHE protein | decreases activity | 12794734 16822217 |
| D014236 | Trichlorfon | [Trichlorfon results in decreased activity of ACHE protein] which affects the localization of CHRM2 protein | affects localization|decreases activity | 12794734 |
| D014236 | Trichlorfon | Trichlorfon results in decreased activity of ACHE protein | decreases activity | 17055053 |
| D014236 | Trichlorfon | Trichlorfon affects the activity of ACHE protein | affects activity | 12111444 |
| D014236 | Trichlorfon | Trichlorfon results in decreased activity of ACHE protein | decreases activity | 11311445 11822883 |
| D014236 | Trichlorfon | Trichlorfon results in decreased activity of ACHE protein | decreases activity | 15957009 |
| C021100 | trichloroacetaldehyde | trichloroacetaldehyde results in decreased activity of ACHE protein | decreases activity | 8292740 |
| D014289 | Trimedoxime | Trimedoxime inhibits the reaction [acephate results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 10681099 |
| D014289 | Trimedoxime | Trimedoxime inhibits the reaction [Trichlorfon results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 10681099 |
| C106320 | trimethylene-bis(4-hydroxyiminomethylpyridinium) | trimethylene-bis(4-hydroxyiminomethylpyridinium) inhibits the reaction [methamidophos results in decreased activity of ACHE protein] | decreases activity|decreases reaction | 7059283 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of ACHE mRNA | increases expression | 19101580 |
| C009680 | VX | VX binds to and results in increased phosphorylation of and results in decreased activity of ACHE protein | affects binding|decreases activity|increases phosphorylation | 17402711 |
| C009680 | VX | VX results in decreased activity of ACHE protein | decreases activity | 12415428 |
| C009680 | VX | VX results in decreased activity of ACHE protein | decreases activity | 16914529 |
| D015038 | Zineb | Zineb results in decreased expression of ACHE protein | decreases expression | 3868355 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000014 | Abnormalities, Drug-Induced | Disulfiram | 23.44 | 17676605 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Ethanol | 23.44 | 17676605 18926900 | |
| MESH:D000014 | Abnormalities, Drug-Induced | mancozeb | 23.44 | 982313 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Maneb | 23.44 | 982313 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Phenobarbital | 23.44 | 6195326 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Phenytoin | 23.44 | 3425630 9118846 6195326 8986270 10563481 9677735 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Valproic Acid | 23.44 | 8875741 | |
| MESH:D000015 | Abnormalities, Multiple | Valproic Acid | 2.91 | 19490988 | |
| MESH:D000138 | Acidosis | Ethanol | 3.40 | 11192467 | |
| MESH:D000142 | Acidosis, Respiratory | Copper Sulfate | 5.30 | 7265320 | |
| MESH:D000163 | Acquired Immunodeficiency Syndrome | Disulfiram | 4.47 | 9207937 | |
| MESH:D058186 | Acute Kidney Injury | Folic Acid | 3.34 | 17003819 16316344 16595132 | |
| MESH:D055371 | Acute Lung Injury | Nickel | 5.82 | 16166738 | |
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 5.82 | 18653653 | |
| MESH:D000230 | Adenocarcinoma | arsenic trioxide | 8.56 | 11798837 19825857 | |
| MESH:D000230 | Adenocarcinoma | Benzo(a)pyrene | 8.56 | 20127859 20464547 | |
| MESH:D000230 | Adenocarcinoma | Estradiol | 8.56 | 11473722 | |
| MESH:D000230 | Adenocarcinoma | Ethylenethiourea | 8.56 | 7955072 | |
| MESH:D000230 | Adenocarcinoma | Sodium Nitrite | 8.56 | 7955072 | |
| MESH:D000236 | Adenoma | Benzo(a)pyrene | 4.41 | 6695378 | |
| MESH:D000236 | Adenoma | Folic Acid | 4.41 | 16963246 | |
| MESH:D018248 | Adenoma, Liver Cell | Phenobarbital | 6.47 | 17620307 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 6.47 | 16434500 | |
| MESH:D000310 | Adrenal Gland Neoplasms | sodium arsenite | 3.57 | 15276417 | |
| MESH:D018246 | Adrenocortical Adenoma | sodium arsenite | 3.77 | 16712894 17306315 | |
| MESH:D000382 | Agricultural Workers' Diseases | alachlor | 73.59 | 14769641 11874814 | |
| MESH:D000382 | Agricultural Workers' Diseases | Atrazine | 73.59 | 11874814 | |
| MESH:D000382 | Agricultural Workers' Diseases | Chlorpyrifos | 73.59 | 11874814 16611668 17119214 | |
| MESH:D000382 | Agricultural Workers' Diseases | cypermethrin | 73.59 | 16487989 | |
| MESH:D000382 | Agricultural Workers' Diseases | Diazinon | 73.59 | 16487989 | |
| MESH:D000382 | Agricultural Workers' Diseases | Dichlorvos | 73.59 | 16611668 17119214 12661182 | |
| MESH:D000382 | Agricultural Workers' Diseases | EPTC | 73.59 | 11874814 | |
| MESH:D000382 | Agricultural Workers' Diseases | Lindane | 73.59 | 12661182 | |
| MESH:D000382 | Agricultural Workers' Diseases | Malathion | 73.59 | 11874814 17119214 | |
| MESH:D000382 | Agricultural Workers' Diseases | mancozeb | 73.59 | 8807224 15864902 16132792 | |
| MESH:D000382 | Agricultural Workers' Diseases | Maneb | 73.59 | 8807224 | |
| MESH:D000382 | Agricultural Workers' Diseases | Monocrotophos | 73.59 | 16487989 | |
| MESH:D000382 | Agricultural Workers' Diseases | Paraquat | 73.59 | 11874814 | |
| MESH:D000382 | Agricultural Workers' Diseases | Parathion | 73.59 | 17119214 11874814 | |
| MESH:D000382 | Agricultural Workers' Diseases | Pesticides | 73.59 | 17119214 | |
| MESH:D000382 | Agricultural Workers' Diseases | Toxaphene | 73.59 | 16132792 | |
| MESH:D000382 | Agricultural Workers' Diseases | Zineb | 73.59 | 8807224 | |
| MESH:D020268 | Alcohol-Induced Disorders, Nervous System | Ethanol | 4.19 | 15451040 15451039 | |
| MESH:D000437 | Alcoholism | Disulfiram | 4.05 | 18968458 10841824 17079463 | |
| MESH:D000505 | Alopecia | Tretinoin | 2.68 | 15955085 | |
| MESH:D000544 | Alzheimer Disease | Aluminum | 17.84 | 17662457 10721010 | |
| MESH:D000544 | Alzheimer Disease | Copper | 17.84 | 16886094 16325427 17119284 16962711 16410023 16866297 | |
| MESH:D000544 | Alzheimer Disease | donepezil | 17.84 | 14744806 | |
| MESH:D000544 | Alzheimer Disease | Folic Acid | 17.84 | 17116317 | |
| MESH:D000544 | Alzheimer Disease | Galantamine | 17.84 | 16914529 17414243 | |
| MESH:D000544 | Alzheimer Disease | huperzine A | 17.84 | 12586202 | |
| MESH:D000544 | Alzheimer Disease | Plant Extracts | 17.84 | 16962711 | |
| MESH:D000544 | Alzheimer Disease | rivastigmine | 17.84 | 17542500 | |
| MESH:D000544 | Alzheimer Disease | Trichlorfon | 17.84 | 11419566 | |
| MESH:D000550 | Amblyopia | Valproic Acid | 4.10 | 17688650 | |
| MESH:D000647 | Amnesia | Desmodium gangeticum extract | 5.81 | 16946593 | |
| MESH:D000690 | Amyotrophic Lateral Sclerosis | Copper | 3.50 | 10694572 | |
| MESH:D000707 | Anaphylaxis | mangiferin | 4.39 | 16536907 14669257 | |
| MESH:D000743 | Anemia, Hemolytic | Quercetin | 3.22 | 17084956 | |
| MESH:D018798 | Anemia, Iron-Deficiency | Copper | 3.88 | 16614410 | |
| MESH:D000755 | Anemia, Sickle Cell | Aspartame | 4.99 | 11372003 | |
| MESH:D000853 | Anophthalmos | Ethanol | 3.73 | 15513904 | |
| MESH:D000860 | Anoxia | Copper Sulfate | 4.82 | 7265320 | |
| MESH:D001004 | Anus Diseases | 3-iodo-2-propynylbutylcarbamate | 6.24 | 14513245 | |
| MESH:D001008 | Anxiety Disorders | Ethanol | 5.87 | 11141031 | |
| MESH:D001008 | Anxiety Disorders | Valproic Acid | 5.87 | 17497229 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Benzo(a)pyrene | 2.99 | 19183758 | |
| MESH:D001169 | Arthritis, Experimental | Plant Extracts | 4.99 | 14686799 | |
| MESH:D001169 | Arthritis, Experimental | Tretinoin | 4.99 | 16412693 | |
| MESH:D001172 | Arthritis, Rheumatoid | Aspartame | 3.76 | 10777254 | |
| MESH:D001172 | Arthritis, Rheumatoid | Tretinoin | 3.76 | 16292516 | |
| MESH:D001249 | Asthma | Acetaldehyde | 7.05 | 9600491 | |
| MESH:D001249 | Asthma | Albuterol | 7.05 | 9949315 11991558 | |
| MESH:D001249 | Asthma | Mustard Gas | 7.05 | 10378619 | |
| MESH:D001249 | Asthma | Tretinoin | 7.05 | 16456186 | |
| MESH:D001260 | Ataxia Telangiectasia | Quercetin | 3.87 | 15336622 | |
| MESH:D050197 | Atherosclerosis | Cadmium | 9.41 | 15687053 | |
| MESH:D050197 | Atherosclerosis | mangiferin | 9.41 | 18450471 | |
| MESH:D050197 | Atherosclerosis | Paraoxon | 9.41 | 16391483 | |
| MESH:D050197 | Atherosclerosis | Phenytoin | 9.41 | 15136057 | |
| MESH:D001289 | Attention Deficit Disorder with Hyperactivity | Pesticides | 4.63 | 20478945 | |
| MESH:D001321 | Autistic Disorder | Folic Acid | 3.81 | 21388746 | |
| MESH:D001321 | Autistic Disorder | Galantamine | 3.81 | 17069550 | |
| MESH:D001321 | Autistic Disorder | Homocysteine | 3.81 | 16297937 20468076 | |
| MESH:D001321 | Autistic Disorder | Memantine | 3.81 | 17690064 | |
| MESH:D001321 | Autistic Disorder | Pesticides | 3.81 | 17938740 | |
| MESH:D001321 | Autistic Disorder | Piracetam | 3.81 | 17929164 | |
| MESH:D001321 | Autistic Disorder | Valproic Acid | 3.81 | 18985861 19460635 17507914 17157402 18558336 17688650 15238991 18177632 18316065 18396377 16609825 18940202 20603192 18775368 19232924 | |
| MESH:D001327 | Autoimmune Diseases | Quercetin | 3.33 | 19761891 | |
| MESH:D001342 | Autonomic Nervous System Diseases | methamidophos | 5.66 | 11527224 | |
| MESH:D001471 | Barrett Esophagus | Tretinoin | 3.33 | 16935849 | |
| MESH:D001480 | Basal Ganglia Diseases | Dichlorvos | 9.77 | 15303389 | |
| MESH:D001480 | Basal Ganglia Diseases | Organophosphorus Compounds | 9.77 | 16804273 | |
| MESH:D001714 | Bipolar Disorder | Valproic Acid | 2.37 | 17594078 20046352 | |
| MESH:D001768 | Blister | Mustard Gas | 4.05 | 19167455 | |
| MESH:D001778 | Blood Coagulation Disorders | arsenic trioxide | 9.50 | 16206674 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 9.50 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | Tretinoin | 9.50 | 16206674 16197459 | |
| MESH:D001848 | Bone Diseases, Developmental | Valproic Acid | 2.58 | 8888407 | |
| MESH:D001862 | Bone Resorption | mangiferin | 3.91 | 9881647 | |
| MESH:D002545 | Brain Ischemia | Plant Extracts | 3.64 | 16041641 | |
| MESH:D001932 | Brain Neoplasms | Copper | 3.58 | 17079463 | |
| MESH:D001943 | Breast Neoplasms | Ascorbic Acid | 9.48 | 16443354 | |
| MESH:D001943 | Breast Neoplasms | Atropine | 9.48 | 12762645 | |
| MESH:D001943 | Breast Neoplasms | Benzo(a)pyrene | 9.48 | 17474063 20146248 | |
| MESH:D001943 | Breast Neoplasms | bexarotene | 9.48 | 16344269 16818667 | |
| MESH:D001943 | Breast Neoplasms | Copper | 9.48 | 17079463 15986119 | |
| MESH:D001943 | Breast Neoplasms | Disulfiram | 9.48 | 17026967 | |
| MESH:D001943 | Breast Neoplasms | Estradiol | 9.48 | 17018787 12948864 16675129 17261762 19861407 17289903 18497071 14630087 | |
| MESH:D001943 | Breast Neoplasms | Folic Acid | 9.48 | 16777985 | |
| MESH:D001943 | Breast Neoplasms | Lindane | 9.48 | 14688026 | |
| MESH:D001943 | Breast Neoplasms | Malathion | 9.48 | 12762645 | |
| MESH:D001943 | Breast Neoplasms | Nickel | 9.48 | 15986119 | |
| MESH:D001943 | Breast Neoplasms | pararosaniline | 9.48 | 11921183 | |
| MESH:D001943 | Breast Neoplasms | Parathion | 9.48 | 12762645 | |
| MESH:D001943 | Breast Neoplasms | Quercetin | 9.48 | 18628248 | |
| MESH:D001943 | Breast Neoplasms | Tretinoin | 9.48 | 16166294 16443354 16873071 | |
| MESH:D001989 | Bronchiolitis Obliterans | Mustard Gas | 4.05 | 15286001 | |
| MESH:D029481 | Bronchitis, Chronic | Mustard Gas | 3.85 | 10378619 17687719 | |
| MESH:D001997 | Bronchopulmonary Dysplasia | Tretinoin | 3.48 | 16813970 | |
| MESH:D002051 | Burkitt Lymphoma | arsenic trioxide | 3.28 | 11589617 | |
| MESH:D002056 | Burns | Ethanol | 3.57 | 16374292 | |
| MESH:D002057 | Burns, Chemical | Plant Extracts | 4.21 | 9625245 | |
| MESH:D002105 | Cadmium Poisoning | Quercetin | 4.42 | 16962696 | |
| MESH:D002177 | Candidiasis | Disulfiram | 4.75 | 15325261 | |
| MESH:D002181 | Candidiasis, Vulvovaginal | Estradiol | 3.35 | 16111702 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Carbon Tetrachloride | 2.71 | 15700767 18705752 15673190 16097048 16227642 16124888 15721981 16011737 16050911 3786805 10355542 16192424 | |
| MESH:D002277 | Carcinoma | Disulfiram | 3.85 | 17026967 | |
| MESH:D018236 | Carcinoma, Embryonal | Tretinoin | 4.03 | 16168501 | |
| MESH:D006528 | Carcinoma, Hepatocellular | arsenic trioxide | 15.11 | 16217749 14691202 15553829 15073043 11135700 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Carbon Tetrachloride | 15.11 | 18788625 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Estradiol | 15.11 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Ethanol | 15.11 | 15289165 15763234 18788625 | |
| MESH:D006528 | Carcinoma, Hepatocellular | malachite green | 15.11 | 12616621 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Phenobarbital | 15.11 | 20007298 17173139 1701930 20935162 6705139 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Plant Extracts | 15.11 | 18834353 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Quercetin | 15.11 | 12508355 19519916 | |
| MESH:D006528 | Carcinoma, Hepatocellular | sodium arsenite | 15.11 | 17306315 16507464 15276417 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Tretinoin | 15.11 | 1917145 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | bexarotene | 4.33 | 16247446 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | Disulfiram | 4.33 | 17026967 | |
| MESH:D021441 | Carcinoma, Pancreatic Ductal | Quercetin | 3.86 | 17234771 | |
| MESH:D002291 | Carcinoma, Papillary | arsenic trioxide | 3.75 | 19014326 | |
| MESH:D018288 | Carcinoma, Small Cell | arsenic trioxide | 3.11 | 12490120 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Benzo(a)pyrene | 4.56 | 20419170 | |
| MESH:D002294 | Carcinoma, Squamous Cell | sodium arsenite | 4.56 | 18572023 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Tretinoin | 4.56 | 16051514 16096774 | |
| MESH:D006332 | Cardiomegaly | Copper | 10.21 | 17327471 | |
| MESH:D006332 | Cardiomegaly | Ethanol | 10.21 | 19332462 | |
| MESH:D006332 | Cardiomegaly | Plant Extracts | 10.21 | 17645561 | |
| MESH:D006332 | Cardiomegaly | Quercetin | 10.21 | 19794523 | |
| MESH:D002310 | Cardiomyopathy, Alcoholic | Acetaldehyde | 5.35 | 10525098 | |
| MESH:D002318 | Cardiovascular Diseases | Folic Acid | 3.13 | 16755160 | |
| MESH:D002386 | Cataract | Disulfiram | 5.32 | 15003327 17936468 | |
| MESH:D002386 | Cataract | Tretinoin | 5.32 | 17460283 | |
| MESH:D002418 | Cattle Diseases | Dichlorvos | 8.49 | 14651886 | |
| MESH:D002418 | Cattle Diseases | Trichlorfon | 8.49 | 14651886 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Cadmium | 9.07 | 17332340 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Cyclosporine | 9.07 | 12371664 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Estradiol | 9.07 | 18566989 | |
| MESH:D002471 | Cell Transformation, Neoplastic | sodium arsenite | 9.07 | 20056578 19524636 | |
| MESH:D002493 | Central Nervous System Diseases | Dichlorvos | 13.37 | 12670839 | |
| MESH:D002493 | Central Nervous System Diseases | Phenobarbital | 13.37 | 4080065 | |
| MESH:D002493 | Central Nervous System Diseases | Phenytoin | 13.37 | 4080065 | |
| MESH:D018290 | Cervical Intraepithelial Neoplasia | Tretinoin | 3.48 | 16129372 | |
| MESH:D002659 | Child Development Disorders, Pervasive | Valproic Acid | 2.16 | 20734317 | |
| MESH:D002779 | Cholestasis | Cyclosporine | 4.78 | 19486331 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 4.78 | 19176532 | |
| OMIM:601042 | CHOREOATHETOSIS/SPASTICITY, EPISODIC | Phenytoin | 4.76 | 11748493 | |
| MESH:D002822 | Choriocarcinoma | Tretinoin | 4.03 | 16461808 | |
| MESH:D019457 | Chromosome Breakage | Sodium Selenite | 3.66 | 15894690 | |
| MESH:D016770 | Ciliophora Infections | malachite green | 4.69 | 16175963 15900690 | |
| MESH:D002971 | Cleft Lip | Ethanol | 8.35 | 15513904 | |
| MESH:D002971 | Cleft Lip | Folic Acid | 8.35 | 21254359 | |
| MESH:D002971 | Cleft Lip | Phenytoin | 8.35 | 2227380 | |
| MESH:D002972 | Cleft Palate | Ethanol | 11.84 | 15513904 | |
| MESH:D002972 | Cleft Palate | Folic Acid | 11.84 | 21254359 8946559 | |
| MESH:D002972 | Cleft Palate | Methanol | 11.84 | 8946559 | |
| MESH:D002972 | Cleft Palate | Phenytoin | 11.84 | 10789828 3877104 1687470 6862529 2227380 6856622 | |
| MESH:D002972 | Cleft Palate | Tretinoin | 11.84 | 9407595 | |
| MESH:D019970 | Cocaine-Related Disorders | Disulfiram | 4.64 | 19462300 | |
| MESH:D003072 | Cognition Disorders | donepezil | 5.78 | 19527754 | |
| MESH:D003092 | Colitis | Selenium | 5.93 | 17936198 | |
| MESH:D003092 | Colitis | Tretinoin | 5.93 | 17035595 | |
| MESH:D003103 | Coloboma | Phenytoin | 4.13 | 9212184 | |
| MESH:D003110 | Colonic Neoplasms | Quercetin | 2.19 | 19056647 19440933 17191121 16640504 11134977 17148506 15741050 | |
| MESH:D015179 | Colorectal Neoplasms | arsenic trioxide | 3.17 | 20501625 | |
| MESH:D015179 | Colorectal Neoplasms | Folic Acid | 3.17 | 17087956 17245555 16963246 16985020 17116713 | |
| MESH:D015179 | Colorectal Neoplasms | Polychlorinated Biphenyls | 3.17 | 15531428 | |
| MESH:D015179 | Colorectal Neoplasms | Quercetin | 3.17 | 18852136 18095365 | |
| MESH:D003128 | Coma | Dichlorvos | 9.78 | 15303389 | |
| MESH:D003128 | Coma | Organophosphorus Compounds | 9.78 | 17098105 | |
| MESH:D003139 | Common Cold | Ascorbic Acid | 4.35 | 17323712 | |
| MESH:D000013 | Congenital Abnormalities | Phenytoin | 3.73 | 10627286 | |
| MESH:D003324 | Coronary Artery Disease | Homocysteine | 3.21 | 16379339 | |
| MESH:D023903 | Coronary Restenosis | arsenic trioxide | 3.12 | 12609071 | |
| MESH:D019465 | Craniofacial Abnormalities | arsenic trioxide | 11.46 | 10525206 | |
| MESH:D019465 | Craniofacial Abnormalities | decamethrin | 11.46 | 19861644 | |
| MESH:D019465 | Craniofacial Abnormalities | Ethanol | 11.46 | 15513904 15451039 11873399 19302082 15451040 11198716 10194807 | |
| MESH:D019465 | Craniofacial Abnormalities | Lead | 11.46 | 19769572 | |
| MESH:D019465 | Craniofacial Abnormalities | Methanol | 11.46 | 15108243 | |
| MESH:D019465 | Craniofacial Abnormalities | Permethrin | 11.46 | 19861644 | |
| MESH:D019465 | Craniofacial Abnormalities | Phenytoin | 11.46 | 8986270 9212184 19952982 | |
| MESH:D019465 | Craniofacial Abnormalities | Tretinoin | 11.46 | 10589399 9224671 17551590 9211117 9664655 16925845 8800419 9142499 9125849 14991402 | |
| MESH:D019465 | Craniofacial Abnormalities | Valproic Acid | 11.46 | 8888407 16575769 17688650 | |
| MESH:D003457 | Cryptosporidiosis | mangiferin | 4.73 | 16547730 | |
| MESH:D003490 | Cyanosis | Endosulfan | 4.46 | 7900959 | |
| MESH:D016757 | Death, Sudden, Cardiac | arsenic trioxide | 3.05 | 15213294 | |
| MESH:D003704 | Dementia | Lead | 7.20 | 16140633 | |
| MESH:D003704 | Dementia | Polychlorinated Biphenyls | 7.20 | 16140633 | |
| MESH:D003731 | Dental Caries | Aspartame | 5.79 | 8955999 | |
| MESH:D017449 | Dermatitis, Allergic Contact | 3-iodo-2-propynylbutylcarbamate | 16.77 | 12755730 14513245 11011936 11298692 17244082 10554066 12022126 9145267 18416770 12000324 | |
| MESH:D017449 | Dermatitis, Allergic Contact | alachlor | 16.77 | 8428444 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Aspartame | 16.77 | 14996049 | |
| MESH:D017449 | Dermatitis, Allergic Contact | mancozeb | 16.77 | 8807224 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Maneb | 16.77 | 8807224 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Nickel | 16.77 | 17244072 17100760 19470301 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Zineb | 16.77 | 8807224 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 1.77 | 18249437 | |
| MESH:D003877 | Dermatitis, Contact | Nickel | 6.66 | 2952479 | |
| MESH:D003877 | Dermatitis, Contact | Permethrin | 6.66 | 14617103 | |
| MESH:D009783 | Dermatitis, Occupational | 3-iodo-2-propynylbutylcarbamate | 16.86 | 17244082 11011936 | |
| MESH:D009783 | Dermatitis, Occupational | mancozeb | 16.86 | 8807224 | |
| MESH:D009783 | Dermatitis, Occupational | Maneb | 16.86 | 8807224 | |
| MESH:D009783 | Dermatitis, Occupational | Zineb | 16.86 | 8807224 | |
| MESH:D002658 | Developmental Disabilities | Memantine | 4.97 | 17016714 | |
| MESH:D003920 | Diabetes Mellitus | Sodium Selenite | 2.81 | 16285004 | |
| MESH:D003921 | Diabetes Mellitus, Experimental | Desmodium gangeticum extract | 8.87 | 17431824 | |
| MESH:D003921 | Diabetes Mellitus, Experimental | mangiferin | 8.87 | 19028559 12093613 | |
| MESH:D003921 | Diabetes Mellitus, Experimental | Quercetin | 8.87 | 19496084 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Ascorbic Acid | 4.89 | 16506275 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Folic Acid | 4.89 | 16886840 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | mangiferin | 4.89 | 9881663 11315760 | |
| MESH:D003928 | Diabetic Nephropathies | Estradiol | 9.64 | 19279558 | |
| MESH:D003928 | Diabetic Nephropathies | mangiferin | 9.64 | 19960420 19706694 | |
| MESH:D003928 | Diabetic Nephropathies | Plant Extracts | 9.64 | 19706694 | |
| MESH:D003967 | Diarrhea | Atropine | 3.96 | 10867622 | |
| OMIM:607208 | DRAVET SYNDROME | Phenytoin | 4.30 | 11748493 | |
| MESH:D003875 | Drug Eruptions | Phenytoin | 4.41 | 15024534 | |
| MESH:D056486 | Drug-Induced Liver Injury | Carbon Tetrachloride | 8.57 | 6884620 21278145 19336974 10915739 10092053 7440962 7179309 15968718 2869522 4309450 15027814 9327722 19085960 17522070 11566570 15998439 3732212 7120509 16227642 6623471 3786805 16177239 | |
| MESH:D056486 | Drug-Induced Liver Injury | Chlorodiphenyl (54% Chlorine) | 8.57 | 17851650 | |
| MESH:D056486 | Drug-Induced Liver Injury | Ethanol | 8.57 | 11566570 | |
| MESH:D056486 | Drug-Induced Liver Injury | Selenium | 8.57 | 15131321 | |
| MESH:D056486 | Drug-Induced Liver Injury | Sodium Selenite | 8.57 | 15131321 | |
| MESH:D056486 | Drug-Induced Liver Injury | Valproic Acid | 8.57 | 19641884 1733752 | |
| MESH:D004381 | Duodenal Ulcer | Atropine | 6.97 | 11595415 | |
| MESH:D004381 | Duodenal Ulcer | Desmodium gangeticum extract | 6.97 | 15991576 | |
| MESH:D004415 | Dyspepsia | Metoclopramide | 6.59 | 8218764 | |
| MESH:D004417 | Dyspnea | Albuterol | 20.35 | 20016425 | |
| MESH:D004417 | Dyspnea | cypermethrin | 20.35 | 16487989 | |
| MESH:D004417 | Dyspnea | Diazinon | 20.35 | 16487989 | |
| MESH:D004417 | Dyspnea | Endosulfan | 20.35 | 3388749 7900959 | |
| MESH:D004417 | Dyspnea | Monocrotophos | 20.35 | 16487989 | |
| MESH:D004421 | Dystonia | Phenobarbital | 12.02 | 1851702 | |
| MESH:D004421 | Dystonia | rivastigmine | 12.02 | 18029952 | |
| MESH:D004421 | Dystonia | Valproic Acid | 12.02 | 1851702 | |
| MESH:C538011 | Eales disease | Ascorbic Acid | 4.35 | 9068938 | |
| MESH:D004487 | Edema | Mustard Gas | 5.95 | 9260866 11428631 11428647 11402378 | |
| MESH:D004487 | Edema | pirinixic acid | 5.95 | 12083418 | |
| MESH:D004487 | Edema | Plant Extracts | 5.95 | 12787963 | |
| MESH:D004489 | Edema, Cardiac | Tretinoin | 3.34 | 18230668 | |
| MESH:D004646 | Emphysema | Endosulfan | 5.42 | 7900959 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Phenytoin | 3.64 | 17654737 | |
| MESH:D016889 | Endometrial Neoplasms | Estradiol | 14.62 | 19148513 11473722 18566989 | |
| MESH:D016889 | Endometrial Neoplasms | Ethylenethiourea | 14.62 | 7955072 | |
| MESH:D016889 | Endometrial Neoplasms | Folic Acid | 14.62 | 17301261 | |
| MESH:D016889 | Endometrial Neoplasms | Sodium Nitrite | 14.62 | 7955072 | |
| MESH:D016889 | Endometrial Neoplasms | Tretinoin | 14.62 | 16569247 | |
| MESH:D004719 | Endomyocardial Fibrosis | Plant Extracts | 4.55 | 15268973 | |
| MESH:D004816 | Epidermal Necrolysis, Toxic | Phenytoin | 4.13 | 20235791 | |
| MESH:D004820 | Epidermolysis Bullosa | Phenytoin | 5.10 | 1399206 6251365 | |
| MESH:D004831 | Epilepsies, Myoclonic | Phenobarbital | 7.20 | 3659116 | |
| MESH:D004831 | Epilepsies, Myoclonic | Valproic Acid | 7.20 | 17275665 3659116 | |
| MESH:D004828 | Epilepsies, Partial | Phenobarbital | 10.54 | 3922381 11558140 | |
| MESH:D004828 | Epilepsies, Partial | Phenytoin | 10.54 | 11558140 17116037 | |
| MESH:D004828 | Epilepsies, Partial | Valproic Acid | 10.54 | 16628512 3922381 | |
| MESH:D004827 | Epilepsy | Phenobarbital | 9.84 | 20417680 | |
| MESH:D004827 | Epilepsy | Phenytoin | 9.84 | 821787 11434505 20417680 | |
| MESH:D004827 | Epilepsy | Plant Extracts | 9.84 | 19439326 19700373 | |
| MESH:D004827 | Epilepsy | Valproic Acid | 9.84 | 18234410 20417680 | |
| MESH:D004832 | Epilepsy, Absence | Phenobarbital | 5.63 | 6401628 | |
| MESH:D004832 | Epilepsy, Absence | Valproic Acid | 5.63 | 6254150 6426943 7562514 | |
| MESH:D017029 | Epilepsy, Complex Partial | Phenobarbital | 13.18 | 7750514 | |
| MESH:D017029 | Epilepsy, Complex Partial | Phenytoin | 13.18 | 7750514 | |
| MESH:D017029 | Epilepsy, Complex Partial | Valproic Acid | 13.18 | 7750514 | |
| MESH:D004830 | Epilepsy, Tonic-Clonic | Phenobarbital | 11.54 | 3659116 | |
| MESH:D004830 | Epilepsy, Tonic-Clonic | Phenytoin | 11.54 | 3659116 | |
| MESH:D004830 | Epilepsy, Tonic-Clonic | Valproic Acid | 11.54 | 3659116 | |
| MESH:D004890 | Erythema | Mustard Gas | 4.05 | 9357497 | |
| MESH:D004893 | Erythema Nodosum | Aspartame | 5.79 | 9324739 | |
| MESH:D004938 | Esophageal Neoplasms | arsenic trioxide | 6.58 | 12903497 | |
| MESH:D004938 | Esophageal Neoplasms | Benzo(a)pyrene | 6.58 | 16530937 | |
| MESH:D004938 | Esophageal Neoplasms | dibutylnitrosamine | 6.58 | 12706858 | |
| MESH:D004938 | Esophageal Neoplasms | Ethanol | 6.58 | 16704527 | |
| MESH:D020329 | Essential Tremor | Lead | 4.82 | 14594619 18007985 | |
| MESH:D017889 | Exfoliation Syndrome | Folic Acid | 9.72 | 16504073 | |
| MESH:D017889 | Exfoliation Syndrome | Homocysteine | 9.72 | 16504073 | |
| MESH:D005124 | Eye Abnormalities | Tretinoin | 2.67 | 16938888 9664655 | |
| MESH:D005141 | Eyelid Diseases | Aspartame | 5.25 | 14996049 | |
| MESH:D005148 | Facial Dermatoses | 3-iodo-2-propynylbutylcarbamate | 6.04 | 11011936 18416770 | |
| MESH:D005234 | Fatty Liver | arsenic trioxide | 25.85 | 15073043 | |
| MESH:D005234 | Fatty Liver | Carbon Tetrachloride | 25.85 | 12795759 16239168 15959796 17595544 19224547 16045604 12631006 61145 | |
| MESH:D005234 | Fatty Liver | Cyclosporine | 25.85 | 19224547 | |
| MESH:D005234 | Fatty Liver | Ethanol | 25.85 | 18620774 19236843 16409862 | |
| MESH:D005234 | Fatty Liver | mangiferin | 25.85 | 15975614 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 25.85 | 19236843 20131406 | |
| MESH:D005234 | Fatty Liver | Plant Extracts | 25.85 | 15975614 | |
| MESH:D005234 | Fatty Liver | Valproic Acid | 25.85 | 19224547 14986274 | |
| MESH:D005235 | Fatty Liver, Alcoholic | Ethanol | 4.53 | 17920746 | |
| MESH:D005310 | Fetal Alcohol Syndrome | Ethanol | 4.19 | 16946407 15451040 10194807 15513904 | |
| MESH:D005313 | Fetal Death | Phenytoin | 4.02 | 10627286 | |
| MESH:D005315 | Fetal Diseases | Valproic Acid | 3.76 | 16575769 | |
| MESH:D005317 | Fetal Growth Retardation | Lead | 7.72 | 19769572 | |
| MESH:D005317 | Fetal Growth Retardation | Valproic Acid | 7.72 | 18558336 8888407 | |
| MESH:D005334 | Fever | Aspartame | 4.34 | 9630831 | |
| MESH:D005355 | Fibrosis | Albuterol | 16.54 | 15467267 | |
| MESH:D005355 | Fibrosis | Carbon Tetrachloride | 16.54 | 18705752 | |
| MESH:D005355 | Fibrosis | Cyclosporine | 16.54 | 12168785 12639820 | |
| MESH:D005355 | Fibrosis | Quercetin | 16.54 | 19474275 | |
| MESH:D005355 | Fibrosis | Tretinoin | 16.54 | 17994277 | |
| MESH:D005393 | Fish Diseases | malachite green | 4.66 | 16175963 15900690 | |
| MESH:D005517 | Foodborne Diseases | methamidophos | 6.01 | 11527224 | |
| MESH:D005706 | Gallbladder Neoplasms | arsenic trioxide | 3.20 | 16904648 | |
| MESH:D005739 | Gas Poisoning | Albuterol | 5.08 | 20016425 | |
| MESH:D005756 | Gastritis | Ethanol | 7.93 | 15046732 | |
| MESH:D005756 | Gastritis | Folic Acid | 7.93 | 17171786 | |
| MESH:D005833 | Genital Neoplasms, Female | sodium arsenite | 3.57 | 16452187 | |
| MESH:D005885 | Gingival Hyperplasia | Cyclosporine | 9.24 | 8708960 | |
| MESH:D005885 | Gingival Hyperplasia | Phenytoin | 9.24 | 9029455 | |
| MESH:D019214 | Gingival Overgrowth | Phenytoin | 5.10 | 16390469 14659971 | |
| MESH:D005901 | Glaucoma | Folic Acid | 8.39 | 16504073 | |
| MESH:D005901 | Glaucoma | Homocysteine | 8.39 | 16504073 | |
| MESH:D005909 | Glioblastoma | Quercetin | 4.51 | 19804834 | |
| MESH:D005909 | Glioblastoma | Tretinoin | 4.51 | 17312396 | |
| MESH:D005910 | Glioma | Quercetin | 2.48 | 17643826 | |
| MESH:D005911 | Gliosis | Maneb | 10.70 | 11124998 | |
| MESH:D005911 | Gliosis | Paraquat | 10.70 | 11124998 | |
| MESH:D006229 | Hand Dermatoses | 3-iodo-2-propynylbutylcarbamate | 6.04 | 17244082 11011936 14513245 | |
| MESH:D006258 | Head and Neck Neoplasms | Tretinoin | 2.35 | 16096774 | |
| MESH:D006317 | Hearing Loss, Noise-Induced | Tretinoin | 4.03 | 16084493 | |
| MESH:D006330 | Heart Defects, Congenital | Ascorbic Acid | 13.29 | 16080930 | |
| MESH:D006330 | Heart Defects, Congenital | Benzo(a)pyrene | 13.29 | 20471113 | |
| MESH:D006330 | Heart Defects, Congenital | Folic Acid | 13.29 | 16524890 17286298 | |
| MESH:D006330 | Heart Defects, Congenital | Homocysteine | 13.29 | 19638421 | |
| MESH:D006330 | Heart Defects, Congenital | Tretinoin | 13.29 | 14991402 9664655 | |
| MESH:D006331 | Heart Diseases | mangiferin | 3.55 | 12093613 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 7.20 | 20558911 | |
| MESH:D006333 | Heart Failure | Plant Extracts | 7.20 | 18097624 | |
| MESH:D006333 | Heart Failure | Selenium | 7.20 | 17162251 | |
| MESH:D006457 | Hemoglobinuria, Paroxysmal | Cyclosporine | 3.31 | 15720958 | |
| MESH:D006470 | Hemorrhage | Endosulfan | 4.28 | 7900959 | |
| MESH:D006505 | Hepatitis | Carbon Tetrachloride | 14.02 | 19900420 19110552 | |
| MESH:D006505 | Hepatitis | cypermethrin | 14.02 | 16487989 | |
| MESH:D006505 | Hepatitis | Diazinon | 14.02 | 16487989 | |
| MESH:D006505 | Hepatitis | Monocrotophos | 14.02 | 16487989 | |
| MESH:D006521 | Hepatitis, Chronic | Copper | 4.16 | 17338147 | |
| MESH:D006527 | Hepatolenticular Degeneration | Copper | 4.09 | 17109627 19888908 17276780 16607473 17182432 | |
| MESH:D006529 | Hepatomegaly | fenvalerate | 8.50 | 15602828 | |
| MESH:D006529 | Hepatomegaly | Phenobarbital | 8.50 | 16109766 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 8.50 | 18467677 19176532 19772884 16221962 | |
| MESH:D006548 | Hernia, Diaphragmatic | Ascorbic Acid | 2.94 | 16863852 16490937 | |
| MESH:D006558 | Herpes Genitalis | Estradiol | 3.90 | 15709030 | |
| MESH:D006561 | Herpes Simplex | mangiferin | 6.79 | 10715843 | |
| MESH:D006561 | Herpes Simplex | Plant Extracts | 6.79 | 10715843 | |
| MESH:D015658 | HIV Infections | Nickel | 4.74 | 17263646 | |
| MESH:D015658 | HIV Infections | Plant Extracts | 4.74 | 12878215 | |
| MESH:D006679 | HIV Seropositivity | Folic Acid | 4.38 | 17209195 | |
| MESH:D006689 | Hodgkin Disease | sodium arsenite | 2.25 | 12676792 | |
| MESH:D006734 | Horse Diseases | Dichlorvos | 4.87 | 16402567 | |
| MESH:D019584 | Hot Flashes | Estradiol | 6.64 | 17088409 | |
| MESH:D019584 | Hot Flashes | Plant Extracts | 6.64 | 14716179 16566672 17454163 | |
| MESH:D006849 | Hydrocephalus | Valproic Acid | 3.76 | 17688650 | |
| MESH:D006930 | Hyperalgesia | Ethanol | 4.93 | 18783367 | |
| MESH:D006930 | Hyperalgesia | Tretinoin | 4.93 | 16870215 | |
| MESH:D006932 | Hyperbilirubinemia | Carbon Tetrachloride | 3.42 | 16899240 | |
| MESH:D017681 | Hypereosinophilic Syndrome | Tretinoin | 3.48 | 16778211 | |
| MESH:D006941 | Hyperesthesia | Dichlorvos | 5.56 | 12563396 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 5.94 | 20558911 | |
| MESH:D006943 | Hyperglycemia | Quercetin | 5.94 | 18262572 11834736 | |
| MESH:D020138 | Hyperhomocysteinemia | Folic Acid | 14.12 | 16865747 16397167 16433478 16755160 16395265 | |
| MESH:D020138 | Hyperhomocysteinemia | Homocysteine | 14.12 | 18234410 17292331 17369066 | |
| MESH:D020138 | Hyperhomocysteinemia | Phenytoin | 14.12 | 10459572 | |
| MESH:D020138 | Hyperhomocysteinemia | Plant Extracts | 14.12 | 16484555 | |
| MESH:D006946 | Hyperinsulinism | mangiferin | 4.03 | 9881663 11315760 | |
| MESH:D006949 | Hyperlipidemias | mangiferin | 6.48 | 15975614 | |
| MESH:D006949 | Hyperlipidemias | Plant Extracts | 6.48 | 15268973 15975614 | |
| MESH:D006967 | Hypersensitivity | mangiferin | 3.72 | 16536907 | |
| MESH:D006973 | Hypertension | Aspartame | 5.41 | 18708962 | |
| MESH:D006973 | Hypertension | Cyclosporine | 5.41 | 10903974 | |
| MESH:D006973 | Hypertension | Quercetin | 5.41 | 18356687 | |
| MESH:D006975 | Hypertension, Portal | Carbon Tetrachloride | 3.00 | 15338365 | |
| MESH:D006976 | Hypertension, Pulmonary | Copper Sulfate | 4.21 | 7265320 | |
| MESH:D007022 | Hypotension | Organophosphorus Compounds | 4.70 | 17098105 | |
| MESH:D007154 | Immune System Diseases | mangiferin | 4.73 | 16076520 | |
| MESH:D007248 | Infertility, Male | alachlor | 30.40 | 16466525 12948887 17049205 | |
| MESH:D007248 | Infertility, Male | Atrazine | 30.40 | 12948887 | |
| MESH:D007248 | Infertility, Male | Diazinon | 30.40 | 16466525 12948887 | |
| MESH:D007248 | Infertility, Male | Endosulfan | 30.40 | 8588293 9432128 | |
| MESH:D007248 | Infertility, Male | Lead | 30.40 | 16780224 | |
| MESH:D007248 | Infertility, Male | methamidophos | 30.40 | 10828210 | |
| MESH:D007248 | Infertility, Male | Paraquat | 30.40 | 4850670 | |
| MESH:D007248 | Infertility, Male | Parathion | 30.40 | 16029889 | |
| MESH:D007248 | Infertility, Male | pirimiphos methyl | 30.40 | 17604518 | |
| MESH:D007248 | Infertility, Male | sodium arsenite | 30.40 | 12646999 15346721 | |
| MESH:D007249 | Inflammation | Aluminum | 10.70 | 16052892 | |
| MESH:D007249 | Inflammation | Desmodium gangeticum extract | 10.70 | 17604372 15507346 | |
| MESH:D007249 | Inflammation | mangiferin | 10.70 | 15222974 | |
| MESH:D007249 | Inflammation | Mustard Gas | 10.70 | 9260866 16001271 17524151 11428647 11428620 9357497 8975870 11428631 11402378 | |
| MESH:D007249 | Inflammation | Nickel | 10.70 | 16166738 | |
| MESH:D007249 | Inflammation | Plant Extracts | 10.70 | 15997105 16366677 12787963 19332304 | |
| MESH:D007251 | Influenza, Human | Quercetin | 7.35 | 16624496 | |
| MESH:D007251 | Influenza, Human | Selenium | 7.35 | 16624496 | |
| MESH:D007299 | Insect Bites and Stings | cypermethrin | 15.11 | 15189238 | |
| MESH:D007299 | Insect Bites and Stings | decamethrin | 15.11 | 15189238 | |
| MESH:D007299 | Insect Bites and Stings | Permethrin | 15.11 | 15189238 12971516 12749493 | |
| MESH:D007333 | Insulin Resistance | Estradiol | 10.85 | 16627594 16393666 | |
| MESH:D007333 | Insulin Resistance | mangiferin | 10.85 | 11315760 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 10.85 | 16306350 | |
| MESH:D007333 | Insulin Resistance | Sodium Selenite | 10.85 | 14714311 | |
| MESH:D007410 | Intestinal Diseases | Tretinoin | 2.70 | 17994277 | |
| MESH:D007414 | Intestinal Neoplasms | Plant Extracts | 3.62 | 12628509 12584176 12351151 | |
| MESH:D007511 | Ischemia | mangiferin | 4.19 | 16806951 | |
| MESH:D007569 | Jaw Abnormalities | Ethanol | 6.94 | 15513904 | |
| MESH:D007569 | Jaw Abnormalities | Tretinoin | 6.94 | 17551590 15992940 | |
| MESH:D007627 | Keloid | Quercetin | 3.86 | 17086741 | |
| MESH:D007638 | Keratoconjunctivitis Sicca | Cyclosporine | 3.31 | 15604871 | |
| MESH:D007674 | Kidney Diseases | Aspartame | 23.92 | 11409539 | |
| MESH:D007674 | Kidney Diseases | Cadmium | 23.92 | 16962696 16226777 16322080 | |
| MESH:D007674 | Kidney Diseases | Cadmium Chloride | 23.92 | 16962696 | |
| MESH:D007674 | Kidney Diseases | Cyclosporine | 23.92 | 18776723 10903974 8314463 | |
| MESH:D007674 | Kidney Diseases | Dichlorvos | 23.92 | 16798900 | |
| MESH:D007674 | Kidney Diseases | Estradiol | 23.92 | 15618244 | |
| MESH:D007674 | Kidney Diseases | mangiferin | 23.92 | 12093613 | |
| MESH:D007674 | Kidney Diseases | Quercetin | 23.92 | 16962696 | |
| MESH:D007674 | Kidney Diseases | sodium arsenite | 23.92 | 20008137 | |
| MESH:D007676 | Kidney Failure, Chronic | Copper | 6.88 | 16518626 | |
| MESH:D007676 | Kidney Failure, Chronic | Selenium | 6.88 | 16518626 | |
| MESH:D007680 | Kidney Neoplasms | Cyclosporine | 4.18 | 12371664 | |
| MESH:D007680 | Kidney Neoplasms | Estradiol | 4.18 | 15610895 | |
| MESH:D007855 | Lead Poisoning | Lead | 4.82 | 16700817 | |
| MESH:D007859 | Learning Disorders | Copper | 23.47 | 17134702 | |
| MESH:D007859 | Learning Disorders | Endosulfan | 23.47 | 8157075 | |
| MESH:D007859 | Learning Disorders | Ethanol | 23.47 | 15451040 | |
| MESH:D007859 | Learning Disorders | Lead | 23.47 | 16384672 | |
| MESH:D007859 | Learning Disorders | mangiferin | 23.47 | 19182383 | |
| MESH:D007859 | Learning Disorders | timosaponin AIII | 23.47 | 19426756 | |
| MESH:D007898 | Leishmaniasis, Visceral | Desmodium gangeticum extract | 4.44 | 1470668 16099649 15763367 | |
| MESH:D007938 | Leukemia | alachlor | 12.19 | 14769641 | |
| MESH:D007938 | Leukemia | arsenic trioxide | 12.19 | 15070760 | |
| MESH:D007938 | Leukemia | Permethrin | 12.19 | 12937054 | |
| MESH:D007938 | Leukemia | Quercetin | 12.19 | 17468513 | |
| MESH:D007938 | Leukemia | Tretinoin | 12.19 | 17143497 | |
| MESH:D015451 | Leukemia, Lymphocytic, Chronic, B-Cell | Disulfiram | 3.57 | 17026967 | |
| MESH:D007945 | Leukemia, Lymphoid | mancozeb | 9.78 | 16132792 | |
| MESH:D007945 | Leukemia, Lymphoid | Toxaphene | 9.78 | 16132792 | |
| MESH:D015459 | Leukemia-Lymphoma, Adult T-Cell | arsenic trioxide | 2.78 | 12560223 17077332 | |
| MESH:D007948 | Leukemia, Monocytic, Acute | arsenic trioxide | 3.20 | 16972261 | |
| MESH:D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | arsenic trioxide | 5.82 | 14633726 | |
| MESH:D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive | mangiferin | 5.82 | 15498116 | |
| MESH:D007951 | Leukemia, Myeloid | arsenic trioxide | 6.10 | 19077051 | |
| MESH:D007951 | Leukemia, Myeloid | Tretinoin | 6.10 | 16932348 16482212 19285840 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | arsenic trioxide | 3.95 | 20471514 19850784 16467208 16968895 17050201 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Tretinoin | 3.95 | 19850784 16294345 17596541 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Valproic Acid | 3.95 | 17596541 16294345 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | arsenic trioxide | 4.86 | 19642359 12018890 19035177 16330433 15213294 15748426 16891316 17712046 19075265 12712474 11468182 9834237 16112521 12679006 17107899 15336539 17649720 17217047 17869043 16331271 11161223 16966277 19225113 16823087 15622746 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | Tretinoin | 4.86 | 16331271 17506722 16935935 12679006 17217047 19225113 17107899 17649720 19035177 16788101 15748426 17294898 17339181 17361223 19642359 16891316 16140955 19075265 17301526 17712046 19029980 9834237 16766008 16823087 17368321 | |
| MESH:D015458 | Leukemia, T-Cell | arsenic trioxide | 3.29 | 16882451 | |
| MESH:D017880 | Limb Deformities, Congenital | Disulfiram | 8.77 | 17676605 | |
| MESH:D017880 | Limb Deformities, Congenital | Ethanol | 8.77 | 17676605 | |
| MESH:D017880 | Limb Deformities, Congenital | Tretinoin | 8.77 | 9224671 | |
| MESH:D008103 | Liver Cirrhosis | Carbon Tetrachloride | 9.61 | 16943688 17157831 16221502 11903743 17174718 21278145 11408273 17334410 16239168 | |
| MESH:D008103 | Liver Cirrhosis | Ethanol | 9.61 | 15289165 | |
| MESH:D008103 | Liver Cirrhosis | Phenobarbital | 9.61 | 21047994 | |
| MESH:D008103 | Liver Cirrhosis | Plant Extracts | 9.61 | 17157831 | |
| MESH:D008104 | Liver Cirrhosis, Alcoholic | Ethanol | 3.99 | 18295389 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | marker/mechanism | 16496349 | ||
| MESH:D008106 | Liver Cirrhosis, Experimental | Carbon Tetrachloride | 6.63 | 18339082 18156304 15818738 18429990 15996030 14716833 18210741 18263696 12741479 15959796 18395914 17631135 17557913 12958196 15362042 16192424 16248980 12632512 10355542 17766677 12586293 16027843 17761835 18420326 18251166 15876570 17708605 18395095 18412020 12609069 18205269 12445421 17721639 17640975 17714472 17976157 18279442 16011737 18376398 12667390 15123356 17525996 15338365 18418968 17805973 13678700 12389079 16033810 12632514 16097048 15057751 17900296 18006644 18187930 17481882 15052691 14748882 20821823 18277467 12445418 16015684 12546737 15893842 11481614 18705752 16638106 15650968 12649538 15370692 12898905 18054572 17869086 16136751 17698563 17922224 17823541 16116963 17944888 15931870 12666154 14620537 18472332 14724832 18166357 17565644 18481824 18472094 14512876 15673190 15925388 14716496 15730626 18317297 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Estradiol | 6.63 | 14716833 14659978 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Ethanol | 6.63 | 18166357 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 6.63 | 15474484 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Plant Extracts | 6.63 | 15479170 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Quercetin | 6.63 | 12741479 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tretinoin | 6.63 | 16248980 18397230 | |
| MESH:D008107 | Liver Diseases | Carbon Tetrachloride | 14.51 | 16246199 16964402 15830285 15720792 17285989 | |
| MESH:D008107 | Liver Diseases | Chlorpyrifos | 14.51 | 15991261 | |
| MESH:D008107 | Liver Diseases | cypermethrin | 14.51 | 15991261 | |
| MESH:D008107 | Liver Diseases | Folic Acid | 14.51 | 16877991 | |
| MESH:D008107 | Liver Diseases | Lindane | 14.51 | 1715830 | |
| MESH:D008107 | Liver Diseases | Phenobarbital | 14.51 | 19363144 | |
| MESH:D008107 | Liver Diseases | Phenytoin | 14.51 | 14986274 | |
| MESH:D008107 | Liver Diseases | Plant Extracts | 14.51 | 17034775 | |
| MESH:D008108 | Liver Diseases, Alcoholic | Ethanol | 3.57 | 17207112 17347304 | |
| MESH:D017093 | Liver Failure | Carbon Tetrachloride | 3.08 | 15123358 | |
| MESH:D017114 | Liver Failure, Acute | Carbon Tetrachloride | 2.70 | 16899240 14706259 | |
| MESH:D008113 | Liver Neoplasms | arsenic trioxide | 23.98 | 14682389 | |
| MESH:D008113 | Liver Neoplasms | Benzo(a)pyrene | 23.98 | 21137059 20195826 | |
| MESH:D008113 | Liver Neoplasms | Carbon Tetrachloride | 23.98 | 19294768 | |
| MESH:D008113 | Liver Neoplasms | Copper | 23.98 | 20302851 | |
| MESH:D008113 | Liver Neoplasms | dibutylnitrosamine | 23.98 | 15881669 | |
| MESH:D008113 | Liver Neoplasms | Ethylenethiourea | 23.98 | 11940454 | |
| MESH:D008113 | Liver Neoplasms | Phenobarbital | 23.98 | 8742319 19073162 21047994 15975961 19482888 19812893 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 23.98 | 15890375 16377806 20007298 | |
| MESH:D008113 | Liver Neoplasms | Plant Extracts | 23.98 | 19168119 | |
| MESH:D008113 | Liver Neoplasms | Quercetin | 23.98 | 18980244 | |
| MESH:D008113 | Liver Neoplasms | sodium arsenite | 23.98 | 15276417 16712894 | |
| MESH:D008114 | Liver Neoplasms, Experimental | arsenic trioxide | 13.02 | 20377131 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Ascorbic Acid | 13.02 | 18544905 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Carbon Tetrachloride | 13.02 | 12014681 15583823 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Phenobarbital | 13.02 | 1399818 2563599 18308698 6150874 17172636 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Polychlorinated Biphenyls | 13.02 | 1423854 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Quercetin | 13.02 | 19519916 | |
| MESH:D008133 | Long QT Syndrome | arsenic trioxide | 2.45 | 15213294 | |
| MESH:D008171 | Lung Diseases | Aluminum | 14.21 | 16052892 | |
| MESH:D008171 | Lung Diseases | Ascorbic Acid | 14.21 | 16863852 | |
| MESH:D008171 | Lung Diseases | chromium hexavalent ion | 14.21 | 16775837 | |
| MESH:D008171 | Lung Diseases | Mustard Gas | 14.21 | 18702808 18161513 | |
| MESH:D008171 | Lung Diseases | sodium arsenite | 14.21 | 19095001 | |
| MESH:D017563 | Lung Diseases, Interstitial | Valproic Acid | 3.14 | 17228818 | |
| MESH:D008175 | Lung Neoplasms | Acetaldehyde | 13.44 | 17372256 | |
| MESH:D008175 | Lung Neoplasms | arsenic trioxide | 13.44 | 19825857 11798837 | |
| MESH:D008175 | Lung Neoplasms | Ascorbic Acid | 13.44 | 16401635 | |
| MESH:D008175 | Lung Neoplasms | Benzo(a)pyrene | 13.44 | 6695378 18816296 20064080 18569708 20869020 17053015 20135361 18520028 20464547 | |
| MESH:D008175 | Lung Neoplasms | bexarotene | 13.44 | 17849452 | |
| MESH:D008175 | Lung Neoplasms | chromium hexavalent ion | 13.44 | 16570259 16876463 | |
| MESH:D008175 | Lung Neoplasms | mangiferin | 13.44 | 18569708 18520028 18816296 | |
| MESH:D008175 | Lung Neoplasms | Mustard Gas | 13.44 | 8781369 3148597 | |
| MESH:D008175 | Lung Neoplasms | Plant Extracts | 13.44 | 20869020 | |
| MESH:D008175 | Lung Neoplasms | Quercetin | 13.44 | 16280456 | |
| MESH:D008175 | Lung Neoplasms | sodium arsenite | 13.44 | 16712894 17077188 15276417 19931552 17306315 | |
| MESH:D008180 | Lupus Erythematosus, Systemic | Folic Acid | 2.89 | 17718048 | |
| MESH:D016393 | Lymphoma, B-Cell | Sodium Selenite | 3.02 | 14737004 | |
| MESH:D016410 | Lymphoma, T-Cell, Cutaneous | bexarotene | 4.06 | 11161223 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | bexarotene | 7.76 | 15591091 19196723 19196722 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Estradiol | 7.76 | 11807958 17203775 16891317 11408345 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | pararosaniline | 7.76 | 11921183 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Selenium | 7.76 | 15318939 | |
| MESH:D020149 | Manganese Poisoning | Estradiol | 3.36 | 19453300 | |
| MESH:D019767 | Maxillofacial Abnormalities | Folic Acid | 4.58 | 16832597 | |
| MESH:D008527 | Medulloblastoma | Tretinoin | 2.19 | 17453147 | |
| MESH:D008545 | Melanoma | Disulfiram | 3.32 | 15367699 | |
| MESH:D008545 | Melanoma | sodium arsenite | 3.32 | 16487513 19082730 | |
| MESH:D008545 | Melanoma | Tretinoin | 3.32 | 16752155 | |
| MESH:D008569 | Memory Disorders | donepezil | 23.45 | 19527754 | |
| MESH:D008569 | Memory Disorders | Ethanol | 23.45 | 15451040 18411066 | |
| MESH:D008569 | Memory Disorders | Lead | 23.45 | 16384672 17263510 | |
| MESH:D008569 | Memory Disorders | mangiferin | 23.45 | 19182383 | |
| MESH:D008569 | Memory Disorders | timosaponin AIII | 23.45 | 19426756 | |
| MESH:D008569 | Memory Disorders | Trichlorfon | 23.45 | 15957009 | |
| MESH:D008591 | Meningomyelocele | Homocysteine | 8.81 | 16602021 | |
| MESH:D008591 | Meningomyelocele | Tretinoin | 8.81 | 16940565 | |
| MESH:D007706 | Menkes Kinky Hair Syndrome | Copper | 4.77 | 17109627 17268249 | |
| MESH:D008607 | Mental Retardation | Phenytoin | 3.15 | 9212184 | |
| MESH:D008654 | Mesothelioma | Atrazine | 4.40 | 1916698 | |
| MESH:D008654 | Mesothelioma | Selenium | 4.40 | 15107826 | |
| MESH:D008664 | Metal Metabolism, Inborn Errors | Cyclosporine | 3.66 | 16801185 | |
| MESH:D008708 | Methemoglobinemia | malachite green | 4.46 | 18363129 | |
| MESH:D008881 | Migraine Disorders | Aspartame | 5.26 | 18627677 10792367 | |
| MESH:D008881 | Migraine Disorders | Valproic Acid | 5.26 | 18765137 18803445 | |
| MESH:D016472 | Motor Neuron Disease | Dichlorvos | 5.21 | 11282359 | |
| MESH:D009062 | Mouth Neoplasms | Benzo(a)pyrene | 2.28 | 16381670 | |
| MESH:D009101 | Multiple Myeloma | alachlor | 4.84 | 14769641 | |
| MESH:D009101 | Multiple Myeloma | arsenic trioxide | 4.84 | 11468182 14977855 19549372 19417148 15949261 | |
| MESH:D020528 | Multiple Sclerosis, Chronic Progressive | Aluminum | 5.25 | 17086897 | |
| MESH:D020529 | Multiple Sclerosis, Relapsing-Remitting | Aluminum | 5.25 | 17086897 | |
| MESH:D018908 | Muscle Weakness | methamidophos | 5.66 | 17849254 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 2.43 | 16239165 | |
| MESH:D009139 | Musculoskeletal Abnormalities | Valproic Acid | 3.01 | 8888407 | |
| MESH:D009182 | Mycosis Fungoides | arsenic trioxide | 3.55 | 18349030 | |
| MESH:D009190 | Myelodysplastic Syndromes | arsenic trioxide | 7.81 | 16882451 16105982 | |
| MESH:D009190 | Myelodysplastic Syndromes | Tretinoin | 7.81 | 17596541 | |
| MESH:D009190 | Myelodysplastic Syndromes | Valproic Acid | 7.81 | 17596541 | |
| MESH:D009203 | Myocardial Infarction | Desmodium gangeticum extract | 11.16 | 15740881 | |
| MESH:D009203 | Myocardial Infarction | Homocysteine | 11.16 | 17412321 | |
| MESH:D009203 | Myocardial Infarction | mangiferin | 11.16 | 16584858 17052832 19172585 16697266 16538859 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 11.16 | 19151258 | |
| MESH:D009203 | Myocardial Infarction | Quercetin | 11.16 | 19595682 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Estradiol | 8.87 | 16810080 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 8.87 | 16411023 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Quercetin | 8.87 | 19207477 | |
| MESH:D020191 | Myoclonic Epilepsies, Progressive | Phenobarbital | 8.82 | 17484760 | |
| MESH:D020191 | Myoclonic Epilepsies, Progressive | Phenytoin | 8.82 | 17484760 | |
| MESH:D009216 | Myopia | Atropine | 4.20 | 12601066 | |
| MESH:D009224 | Myotonia Congenita | Phenytoin | 4.30 | 1896199 | |
| MESH:D009349 | Nematode Infections | Dichlorvos | 5.02 | 16402567 | |
| MESH:D009361 | Neoplasm Invasiveness | arsenic trioxide | 7.15 | 16624393 | |
| MESH:D009361 | Neoplasm Invasiveness | Disulfiram | 7.15 | 18047805 | |
| MESH:D009362 | Neoplasm Metastasis | Disulfiram | 3.45 | 15367699 | |
| MESH:D009369 | Neoplasms | Aspartame | 21.91 | 16507461 | |
| MESH:D009369 | Neoplasms | Benzo(a)pyrene | 21.91 | 11141357 | |
| MESH:D009369 | Neoplasms | Disulfiram | 21.91 | 17079463 | |
| MESH:D009369 | Neoplasms | fenvalerate | 21.91 | 2895627 | |
| MESH:D009369 | Neoplasms | Lindane | 21.91 | 16818664 12807735 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 21.91 | 17405874 | |
| MESH:D009369 | Neoplasms | Quercetin | 21.91 | 15185748 | |
| MESH:D009369 | Neoplasms | sodium arsenite | 21.91 | 11559025 | |
| MESH:D009369 | Neoplasms | Toxaphene | 21.91 | 8820588 | |
| MESH:D009369 | Neoplasms | Tretinoin | 21.91 | 16594593 16946489 | |
| MESH:D009374 | Neoplasms, Experimental | sodium arsenite | 2.61 | 20056578 | |
| MESH:D009376 | Neoplasms, Hormone-Dependent | bexarotene | 3.67 | 19196722 | |
| MESH:D009389 | Neovascularization, Pathologic | Copper | 10.90 | 17308104 | |
| MESH:D009389 | Neovascularization, Pathologic | Disulfiram | 10.90 | 15367699 | |
| MESH:D009389 | Neovascularization, Pathologic | Estradiol | 10.90 | 17289903 | |
| MESH:D009402 | Nephrosis, Lipoid | Cyclosporine | 3.31 | 17954296 | |
| MESH:D009404 | Nephrotic Syndrome | Cyclosporine | 2.31 | 18481113 19348381 | |
| MESH:D009410 | Nerve Degeneration | Dichlorvos | 16.61 | 11282359 17850875 | |
| MESH:D009410 | Nerve Degeneration | mancozeb | 16.61 | 15350641 | |
| MESH:D009410 | Nerve Degeneration | Maneb | 16.61 | 15350641 16893418 | |
| MESH:D009410 | Nerve Degeneration | mangiferin | 16.61 | 17433543 | |
| MESH:D009410 | Nerve Degeneration | Paraquat | 16.61 | 16893418 | |
| MESH:D009422 | Nervous System Diseases | methamidophos | 4.66 | 2238440 15938848 | |
| MESH:D009421 | Nervous System Malformations | Estradiol | 6.16 | 16427766 11399458 | |
| MESH:D009421 | Nervous System Malformations | Tretinoin | 6.16 | 9125849 | |
| MESH:D009436 | Neural Tube Defects | arsenic trioxide | 21.56 | 10525206 | |
| MESH:D009436 | Neural Tube Defects | Folic Acid | 21.56 | 17438019 | |
| MESH:D009436 | Neural Tube Defects | mancozeb | 21.56 | 15864902 | |
| MESH:D009436 | Neural Tube Defects | Phenytoin | 21.56 | 9118846 | |
| MESH:D009436 | Neural Tube Defects | sodium arsenite | 21.56 | 12854658 | |
| MESH:D009436 | Neural Tube Defects | Tretinoin | 21.56 | 9142499 | |
| MESH:D009436 | Neural Tube Defects | Valproic Acid | 21.56 | 8888407 16359493 | |
| OMIM:601634 | NEURAL TUBE DEFECTS, FOLATE-SENSITIVE | Methanol | 5.45 | 8946559 | |
| MESH:D019954 | Neurobehavioral Manifestations | Plant Extracts | 4.10 | 17168769 | |
| MESH:D019636 | Neurodegenerative Diseases | Dichlorvos | 3.98 | 16635102 | |
| MESH:D020078 | Neurogenic Inflammation | Quercetin | 3.32 | 17929310 | |
| MESH:D020258 | Neurotoxicity Syndromes | Aldicarb | 24.22 | 15081274 | |
| MESH:D020258 | Neurotoxicity Syndromes | Chlorpyrifos | 24.22 | 15081274 | |
| MESH:D020258 | Neurotoxicity Syndromes | Dichlorvos | 24.22 | 12186780 | |
| MESH:D020258 | Neurotoxicity Syndromes | Disulfiram | 24.22 | 11005259 | |
| MESH:D020258 | Neurotoxicity Syndromes | Insecticides | 24.22 | 19861644 | |
| MESH:D020258 | Neurotoxicity Syndromes | Malathion | 24.22 | 15081274 | |
| MESH:D020258 | Neurotoxicity Syndromes | Methyl Parathion | 24.22 | 19784758 | |
| MESH:D009503 | Neutropenia | Folic Acid | 6.17 | 16322990 | |
| MESH:D009503 | Neutropenia | Mustard Gas | 6.17 | 16761898 7688884 | |
| MESH:D009669 | Nose Neoplasms | alachlor | 6.45 | 11127290 14563481 16698726 15580706 16178123 | |
| MESH:D009669 | Nose Neoplasms | chromium hexavalent ion | 6.45 | 16876463 | |
| MESH:D009765 | Obesity | Ascorbic Acid | 4.90 | 17217161 | |
| MESH:D009765 | Obesity | pirinixic acid | 4.90 | 20558911 | |
| MESH:D009765 | Obesity | Plant Extracts | 4.90 | 20132043 19056576 | |
| MESH:D010003 | Osteoarthritis | Aspartame | 4.10 | 9630831 | |
| MESH:D010018 | Osteomalacia | Phenobarbital | 8.41 | 17016548 | |
| MESH:D010018 | Osteomalacia | Phenytoin | 8.41 | 17016548 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | Quercetin | 3.18 | 19495926 | |
| MESH:D012516 | Osteosarcoma | Disulfiram | 4.23 | 18047805 | |
| MESH:D010051 | Ovarian Neoplasms | arsenic trioxide | 11.83 | 19769630 16624393 12452020 | |
| MESH:D010051 | Ovarian Neoplasms | Disulfiram | 11.83 | 17026967 | |
| MESH:D010051 | Ovarian Neoplasms | Estradiol | 11.83 | 19401270 | |
| MESH:D010051 | Ovarian Neoplasms | Quercetin | 11.83 | 19005980 | |
| MESH:D010051 | Ovarian Neoplasms | sodium arsenite | 11.83 | 15276417 17306315 | |
| MESH:D010051 | Ovarian Neoplasms | Tretinoin | 11.83 | 16936753 | |
| MESH:D010146 | Pain | Aspartame | 8.73 | 9630831 | |
| MESH:D010146 | Pain | Desmodium gangeticum extract | 8.73 | 15507346 | |
| MESH:D010146 | Pain | Phenytoin | 8.73 | 15215642 | |
| MESH:D010146 | Pain | Tretinoin | 8.73 | 16870215 | |
| MESH:D010190 | Pancreatic Neoplasms | arsenic trioxide | 15.88 | 15580305 | |
| MESH:D010190 | Pancreatic Neoplasms | EPTC | 15.88 | 19142867 | |
| MESH:D010190 | Pancreatic Neoplasms | Ethanol | 15.88 | 12384795 | |
| MESH:D010190 | Pancreatic Neoplasms | mancozeb | 15.88 | 8603375 16965848 | |
| MESH:D010190 | Pancreatic Neoplasms | Phenobarbital | 15.88 | 16965848 | |
| MESH:D010190 | Pancreatic Neoplasms | Quercetin | 15.88 | 16965848 | |
| MESH:D010190 | Pancreatic Neoplasms | Tretinoin | 15.88 | 15976015 | |
| MESH:D010195 | Pancreatitis | Dichlorvos | 8.83 | 16258382 | |
| MESH:D010195 | Pancreatitis | Insecticides | 8.83 | 16258382 3421227 | |
| MESH:D010195 | Pancreatitis | Methomyl | 8.83 | 15767733 16258382 | |
| MESH:D010212 | Papilloma | Plant Extracts | 3.43 | 16517061 15173996 | |
| MESH:D010235 | Paraganglioma | arsenic trioxide | 3.12 | 19927285 | |
| MESH:D010243 | Paralysis | fenvalerate | 4.89 | 8952708 | |
| MESH:D010300 | Parkinson Disease | Atrazine | 12.75 | 17218051 | |
| MESH:D010300 | Parkinson Disease | Homocysteine | 12.75 | 16275827 | |
| MESH:D010300 | Parkinson Disease | Maneb | 12.75 | 12911755 16140633 15824117 11124998 16510128 | |
| MESH:D010300 | Parkinson Disease | mangiferin | 12.75 | 17433543 | |
| MESH:D010300 | Parkinson Disease | Paraquat | 12.75 | 15824117 11445065 11124998 12911755 11181820 16510128 16140633 15451049 | |
| MESH:D010300 | Parkinson Disease | Polychlorinated Biphenyls | 12.75 | 16702228 | |
| MESH:D010302 | Parkinson Disease, Secondary | Dichlorvos | 7.85 | 12645970 | |
| MESH:D010302 | Parkinson Disease, Secondary | Paraquat | 7.85 | 16190885 | |
| MESH:D010518 | Periodontitis | mangiferin | 4.48 | 19026997 | |
| MESH:D010523 | Peripheral Nervous System Diseases | methamidophos | 4.71 | 2170085 7654138 10447555 | |
| MESH:D016491 | Peripheral Vascular Diseases | Cadmium | 4.27 | 15687053 | |
| MESH:D010954 | Plasmacytoma | Selenium | 3.76 | 15087411 | |
| MESH:D011014 | Pneumonia | Paraquat | 3.35 | 12504350 | |
| MESH:D011017 | Pneumonia, Lipid | Phosphoric Acid Esters | 6.58 | 12803600 | |
| MESH:D011041 | Poisoning | marker/mechanism | 17098105 | ||
| MESH:D011041 | Poisoning | Atropine | 77.45 | 18072136 17849254 | |
| MESH:D011041 | Poisoning | Diazinon | 77.45 | 17603234 | |
| MESH:D011041 | Poisoning | Dichlorvos | 77.45 | 12460839 18072136 16036766 17157343 17603234 15303389 | |
| MESH:D011041 | Poisoning | Galantamine | 77.45 | 16914529 | |
| MESH:D011041 | Poisoning | Memantine | 77.45 | 15824473 | |
| MESH:D011041 | Poisoning | methamidophos | 77.45 | 16119251 17849254 | |
| MESH:D011041 | Poisoning | Methomyl | 77.45 | 11800311 | |
| MESH:D011041 | Poisoning | Methyl Parathion | 77.45 | 17603234 | |
| MESH:D011041 | Poisoning | Mustard Gas | 77.45 | 15727166 | |
| MESH:D011041 | Poisoning | N(6)-cyclopentyladenosine | 77.45 | 16105447 | |
| MESH:D011041 | Poisoning | Obidoxime Chloride | 77.45 | 8134223 | |
| MESH:D011041 | Poisoning | Organophosphorus Compounds | 77.45 | 17098105 | |
| MESH:D011041 | Poisoning | Physostigmine | 77.45 | 17157343 | |
| MESH:D011041 | Poisoning | pralidoxime | 77.45 | 16105446 17849254 8134223 | |
| MESH:D011041 | Poisoning | Sarin | 77.45 | 16914529 | |
| MESH:D011041 | Poisoning | Soman | 77.45 | 16914529 | |
| MESH:D011041 | Poisoning | Tiapride | 77.45 | 16036766 | |
| MESH:D017689 | Polydactyly | Phenytoin | 4.06 | 9212184 | |
| MESH:D011115 | Polyneuropathies | Dichlorvos | 12.85 | 12563396 | |
| MESH:D011115 | Polyneuropathies | methamidophos | 12.85 | 7654138 | |
| MESH:D011115 | Polyneuropathies | Organophosphorus Compounds | 12.85 | 16042503 | |
| MESH:D011230 | Precancerous Conditions | Cyclosporine | 9.70 | 12371664 | |
| MESH:D011230 | Precancerous Conditions | Phenobarbital | 9.70 | 2563599 | |
| MESH:D011230 | Precancerous Conditions | Quercetin | 9.70 | 19056647 | |
| MESH:D011248 | Pregnancy Complications | Toxaphene | 4.78 | 2087686 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Lead | 10.48 | 16384672 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Pesticides | 10.48 | 17938740 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Valproic Acid | 10.48 | 20603192 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | Estradiol | 2.86 | 20887781 | |
| MESH:D011471 | Prostatic Neoplasms | arsenic trioxide | 3.92 | 19131511 | |
| MESH:D011471 | Prostatic Neoplasms | Benzo(a)pyrene | 3.92 | 17292933 | |
| MESH:D011471 | Prostatic Neoplasms | Cadmium | 3.92 | 17075824 | |
| MESH:D011471 | Prostatic Neoplasms | Copper | 3.92 | 17308104 17079463 | |
| MESH:D011471 | Prostatic Neoplasms | Dichlorvos | 3.92 | 12661182 | |
| MESH:D011471 | Prostatic Neoplasms | Disulfiram | 3.92 | 19789329 | |
| MESH:D011471 | Prostatic Neoplasms | Estradiol | 3.92 | 16740699 | |
| MESH:D011471 | Prostatic Neoplasms | Lindane | 3.92 | 14688026 12661182 | |
| MESH:D011471 | Prostatic Neoplasms | Plant Extracts | 3.92 | 14666653 17804756 | |
| MESH:D011471 | Prostatic Neoplasms | Polychlorinated Biphenyls | 3.92 | 15721890 | |
| MESH:D011471 | Prostatic Neoplasms | Quercetin | 3.92 | 17292933 14715546 | |
| MESH:D011471 | Prostatic Neoplasms | sodium arsenite | 3.92 | 16039940 | |
| MESH:D011471 | Prostatic Neoplasms | Sodium Selenite | 3.92 | 18760546 | |
| MESH:D011507 | Proteinuria | Tretinoin | 2.58 | 16636307 | |
| MESH:D011537 | Pruritus | Mustard Gas | 3.01 | 18058305 | |
| MESH:D019310 | Pseudolymphoma | Phenobarbital | 14.70 | 12752131 | |
| MESH:D019310 | Pseudolymphoma | Phenytoin | 14.70 | 1419762 12752131 8603615 | |
| MESH:D019310 | Pseudolymphoma | Valproic Acid | 14.70 | 11422049 12752131 | |
| MESH:D011565 | Psoriasis | Cyclosporine | 1.70 | 16882103 | |
| MESH:D011625 | Pterygium | Tretinoin | 3.68 | 16723453 | |
| MESH:D011657 | Pulmonary Eosinophilia | Ascorbic Acid | 4.21 | 14606601 | |
| MESH:D011658 | Pulmonary Fibrosis | Mustard Gas | 3.88 | 17620002 17266442 17720292 10334151 17894541 | |
| MESH:D011658 | Pulmonary Fibrosis | Paraquat | 3.88 | 17997886 16324872 | |
| MESH:D011833 | Radiation Injuries, Experimental | mangiferin | 5.28 | 15830843 | |
| MESH:D051437 | Renal Insufficiency | Folic Acid | 3.70 | 15728788 | |
| MESH:D015427 | Reperfusion Injury | Desmodium gangeticum extract | 4.86 | 18380926 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 4.86 | 19058328 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Paraquat | 2.89 | 11700416 | |
| MESH:D012130 | Respiratory Hypersensitivity | Acetylcholine | 3.41 | 9413022 | |
| MESH:D012131 | Respiratory Insufficiency | Dichlorvos | 8.73 | 15303389 17350689 | |
| MESH:D012131 | Respiratory Insufficiency | Organophosphorus Compounds | 8.73 | 16449848 17098105 | |
| MESH:D012135 | Respiratory Sounds | alachlor | 39.25 | 11874814 | |
| MESH:D012135 | Respiratory Sounds | Atrazine | 39.25 | 11874814 | |
| MESH:D012135 | Respiratory Sounds | Chlorpyrifos | 39.25 | 16611668 17119214 11874814 | |
| MESH:D012135 | Respiratory Sounds | Dichlorvos | 39.25 | 17119214 16611668 | |
| MESH:D012135 | Respiratory Sounds | EPTC | 39.25 | 11874814 | |
| MESH:D012135 | Respiratory Sounds | Malathion | 39.25 | 11874814 17119214 | |
| MESH:D012135 | Respiratory Sounds | Paraquat | 39.25 | 11874814 | |
| MESH:D012135 | Respiratory Sounds | Parathion | 39.25 | 17119214 11874814 | |
| MESH:D012135 | Respiratory Sounds | Pesticides | 39.25 | 17119214 | |
| MESH:D012140 | Respiratory Tract Diseases | Chlorpyrifos | 21.35 | 16611668 17119214 | |
| MESH:D012140 | Respiratory Tract Diseases | Dichlorvos | 21.35 | 17119214 16611668 | |
| MESH:D012140 | Respiratory Tract Diseases | Malathion | 21.35 | 17119214 | |
| MESH:D012140 | Respiratory Tract Diseases | Parathion | 21.35 | 17119214 | |
| MESH:D012140 | Respiratory Tract Diseases | Pesticides | 21.35 | 17119214 | |
| MESH:D012162 | Retinal Degeneration | Paraquat | 2.97 | 16458197 | |
| MESH:D012174 | Retinitis Pigmentosa | Ascorbic Acid | 2.87 | 16849425 | |
| MESH:D012208 | Rhabdomyosarcoma | Tretinoin | 7.40 | 16283617 16116481 | |
| MESH:D012208 | Rhabdomyosarcoma | Valproic Acid | 7.40 | 19155313 | |
| MESH:D012220 | Rhinitis | Acetaldehyde | 3.77 | 17050345 | |
| MESH:D012512 | Sarcoma, Ewing's | arsenic trioxide | 2.90 | 16646077 | |
| MESH:D012554 | Schistosomiasis japonica | Quercetin | 4.42 | 16862918 | |
| MESH:D012559 | Schizophrenia | Copper | 5.26 | 16842975 | |
| MESH:D012559 | Schizophrenia | Folic Acid | 5.26 | 16641680 | |
| MESH:D012559 | Schizophrenia | Homocysteine | 5.26 | 16641680 | |
| MESH:D012559 | Schizophrenia | Valproic Acid | 5.26 | 15737665 19110320 | |
| MESH:D012640 | Seizures | Atropine | 31.88 | 17157343 12660363 11218047 | |
| MESH:D012640 | Seizures | Chlorfenvinphos | 31.88 | 11218047 | |
| MESH:D012640 | Seizures | Dichlorvos | 31.88 | 12660363 17157343 | |
| MESH:D012640 | Seizures | Endosulfan | 31.88 | 7539098 10698677 | |
| MESH:D012640 | Seizures | Ethanol | 31.88 | 9754883 | |
| MESH:D012640 | Seizures | Lindane | 31.88 | 7539098 12842176 15475178 | |
| MESH:D012640 | Seizures | Methomyl | 31.88 | 11218047 12660363 | |
| MESH:D012640 | Seizures | Phenobarbital | 31.88 | 16876388 11442880 3137016 4039156 | |
| MESH:D012640 | Seizures | Phenytoin | 31.88 | 19919933 10029267 9844417 11044598 3691417 3137016 16876388 15946322 | |
| MESH:D012640 | Seizures | Physostigmine | 31.88 | 17157343 | |
| MESH:D012640 | Seizures | Soman | 31.88 | 10087439 | |
| MESH:D012640 | Seizures | Valproic Acid | 31.88 | 16876388 15475178 14763951 17978042 11044598 11738929 1511512 3137016 | |
| MESH:D003294 | Seizures, Febrile | Phenobarbital | 3.71 | 6407741 | |
| MESH:D012729 | Sex Chromosome Aberrations | Chlorpyrifos | 4.96 | 6418539 | |
| MESH:D012772 | Shock, Septic | mangiferin | 4.14 | 15177305 | |
| MESH:D012859 | Sjogren's Syndrome | Aspartame | 5.45 | 16800424 | |
| MESH:D012871 | Skin Diseases | Ascorbic Acid | 5.39 | 18709164 | |
| MESH:D012871 | Skin Diseases | Folic Acid | 5.39 | 18709164 | |
| MESH:D012871 | Skin Diseases | Mustard Gas | 5.39 | 15451306 16961503 12880345 | |
| MESH:D012878 | Skin Neoplasms | Benzo(a)pyrene | 13.60 | 19755658 10029692 | |
| MESH:D012878 | Skin Neoplasms | mancozeb | 13.60 | 1733566 | |
| MESH:D012878 | Skin Neoplasms | Plant Extracts | 13.60 | 15173996 16517061 | |
| MESH:D012878 | Skin Neoplasms | sodium arsenite | 13.60 | 19524636 18572023 | |
| MESH:D012878 | Skin Neoplasms | tert-Butylhydroperoxide | 13.60 | 8532709 | |
| MESH:D012878 | Skin Neoplasms | Tretinoin | 13.60 | 16467112 | |
| MESH:D013118 | Spinal Cord Diseases | Folic Acid | 4.38 | 16361298 | |
| MESH:D016135 | Spinal Dysraphism | sodium arsenite | 6.46 | 12854658 | |
| MESH:D016135 | Spinal Dysraphism | Valproic Acid | 6.46 | 19490988 | |
| MESH:D013226 | Status Epilepticus | Valproic Acid | 3.42 | 12833885 | |
| MESH:D013262 | Stevens-Johnson Syndrome | Phenytoin | 4.07 | 20235791 | |
| MESH:D013274 | Stomach Neoplasms | arsenic trioxide | 5.23 | 17007042 | |
| MESH:D013274 | Stomach Neoplasms | Benzo(a)pyrene | 5.23 | 20155912 2093021 | |
| MESH:D013274 | Stomach Neoplasms | Dichlorvos | 5.23 | 11397402 | |
| MESH:D013274 | Stomach Neoplasms | Ethanol | 5.23 | 18456281 | |
| MESH:D013274 | Stomach Neoplasms | Folic Acid | 5.23 | 17171786 | |
| MESH:D013274 | Stomach Neoplasms | Tretinoin | 5.23 | 17261132 | |
| MESH:D013276 | Stomach Ulcer | Ascorbic Acid | 18.78 | 18726076 | |
| MESH:D013276 | Stomach Ulcer | Atropine | 18.78 | 11595415 | |
| MESH:D013276 | Stomach Ulcer | Desmodium gangeticum extract | 18.78 | 15991576 | |
| MESH:D013276 | Stomach Ulcer | Ethanol | 18.78 | 11906479 9562338 17918041 17189318 16755016 9211565 | |
| MESH:D013276 | Stomach Ulcer | mangiferin | 18.78 | 17918041 | |
| MESH:D013276 | Stomach Ulcer | Plant Extracts | 18.78 | 18237397 12787963 17135157 15255614 18193104 | |
| MESH:D013276 | Stomach Ulcer | Ranitidine | 18.78 | 18726076 17895592 18087811 17135157 16397915 | |
| MESH:D020521 | Stroke | Ascorbic Acid | 6.07 | 16517955 16403987 | |
| MESH:D020521 | Stroke | Folic Acid | 6.07 | 16517955 | |
| MESH:D013322 | Strongyloidiasis | Dichlorvos | 10.30 | 14651886 | |
| MESH:D013322 | Strongyloidiasis | Trichlorfon | 10.30 | 14651886 | |
| MESH:D013375 | Substance Withdrawal Syndrome | Ethanol | 3.26 | 9754883 | |
| MESH:D013705 | Temporomandibular Joint Disorders | Plant Extracts | 4.35 | 17997062 | |
| MESH:D013921 | Thrombocytopenia | Aspartame | 4.49 | 17534100 | |
| MESH:D013964 | Thyroid Neoplasms | alachlor | 12.98 | 8812207 | |
| MESH:D013964 | Thyroid Neoplasms | arsenic trioxide | 12.98 | 19014326 | |
| MESH:D013964 | Thyroid Neoplasms | Ethylenethiourea | 12.98 | 11940454 | |
| MESH:D013964 | Thyroid Neoplasms | Phenobarbital | 12.98 | 1399818 | |
| MESH:D013964 | Thyroid Neoplasms | Tretinoin | 12.98 | 16026305 17045167 | |
| MESH:D013978 | Tibial Fractures | Estradiol | 3.56 | 19048282 | |
| MESH:D014062 | Tongue Neoplasms | Tretinoin | 2.79 | 16051514 | |
| MESH:D016171 | Torsades de Pointes | arsenic trioxide | 2.87 | 15213294 | |
| MESH:D014178 | Translocation, Genetic | Valproic Acid | 4.10 | 17262798 | |
| MESH:D014202 | Tremor | Atropine | 12.04 | 17594079 | |
| MESH:D014202 | Tremor | fenvalerate | 12.04 | 8952708 | |
| MESH:D014202 | Tremor | Lead | 12.04 | 21145352 | |
| MESH:D014235 | Trichinellosis | mangiferin | 4.93 | 14669257 | |
| MESH:D014376 | Tuberculosis | Tretinoin | 2.43 | 16040207 | |
| MESH:D020194 | Unverricht-Lundborg Syndrome | Valproic Acid | 3.41 | 3119515 | |
| MESH:D001749 | Urinary Bladder Neoplasms | arsenic trioxide | 9.32 | 11780464 12845720 20435036 12973940 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Benzo(a)pyrene | 9.32 | 17053015 | |
| MESH:D001749 | Urinary Bladder Neoplasms | dibutylnitrosamine | 9.32 | 12706858 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Quercetin | 9.32 | 16720314 | |
| MESH:D001749 | Urinary Bladder Neoplasms | sodium arsenite | 9.32 | 16712894 16452187 11723127 17306315 | |
| MESH:D014564 | Urogenital Abnormalities | Valproic Acid | 3.55 | 8888407 | |
| MESH:D014570 | Urologic Diseases | cypermethrin | 14.37 | 16487989 | |
| MESH:D014570 | Urologic Diseases | Diazinon | 14.37 | 16487989 | |
| MESH:D014570 | Urologic Diseases | Monocrotophos | 14.37 | 16487989 | |
| MESH:D002583 | Uterine Cervical Neoplasms | sodium arsenite | 6.10 | 11813266 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Tretinoin | 6.10 | 16129372 | |
| MESH:D014604 | Uveal Neoplasms | Tretinoin | 3.48 | 16752155 | |
| MESH:D014605 | Uveitis | Cyclosporine | 2.86 | 1336536 | |
| MESH:D014652 | Vascular Diseases | sodium arsenite | 3.32 | 17056641 | |
| MESH:D018487 | Ventricular Dysfunction, Left | Plant Extracts | 3.67 | 18097624 | |
| MESH:D020257 | Ventricular Remodeling | Plant Extracts | 4.21 | 18097624 | |
| MESH:D014820 | Vitiligo | Tretinoin | 2.99 | 16761959 | |
| MESH:D009396 | Wilms Tumor | Tretinoin | 2.98 | 16287080 | |
| MESH:D014947 | Wounds and Injuries | Plant Extracts | 3.32 | 19894650 20213670 | |
| MESH:D014985 | Xerophthalmia | Cyclosporine | 3.31 | 17120751 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:00564 | Glycerophospholipid metabolism |
| REACT:13685 | Synaptic Transmission |
| Drugbank ID | Action | Drug Name | Description |
|---|---|---|---|
| DB00122 | - | Choline | Dietary supplement;Micronutrient;Nootropic Agents;Lipotropic Agents |
| DB00382 | inhibitor | Tacrine | Parasympathomimetics;Cholinesterase Inhibitors;Nootropic Agents |
| DB00483 | antagonist | Gallamine Triethiodide | Skeletal Muscle Relaxants;Neuromuscular Nondepolarizing Agents;Nicotinic Antagonists |
| DB00545 | inhibitor | Pyridostigmine | Parasympathomimetics;Cholinesterase Inhibitors;Antimyasthenics |
| DB00674 | inhibitor | Galantamine | Parasympathomimetics;Cholinesterase Inhibitors;Nootropic Agents |
| DB00677 | antagonist | Isoflurophate | Protease Inhibitors;Cholinesterase Inhibitors;Miotics;Antiglaucomic Agents;Ophthalmics |
| DB00733 | activator | Pralidoxime | Antidotes;Cholinesterase Reactivators |
| DB00805 | antagonist | Minaprine | Central Nervous System Agents;Antiparkinson Agents;Antidepressive Agents |
| DB00843 | inhibitor | Donepezil | Parasympathomimetics;Cholinesterase Inhibitors;Nootropic Agents |
| DB00944 | antagonist | Demecarium | Miotics;Cholinergic Agents |
| DB00981 | antagonist | Physostigmine | Cholinesterase Inhibitors;Miotics |
| DB00989 | inhibitor | Rivastigmine | Parasympathomimetics;Neuroprotective Agents;Cholinesterase Inhibitors;Nootropic Agents;Cholinergic Agents |
| DB01010 | antagonist | Edrophonium | Cholinesterase Inhibitors;Antidotes |
| DB01122 | inhibitor | Ambenonium | Antiarrhythmic Agents;Antimyasthenics |
| DB01199 | allosteric modulator | Tubocurarine | Skeletal Muscle Relaxants;Neuromuscular Nondepolarizing Agents;Nicotinic Antagonists |
| DB01245 | antagonist | Decamethonium | Neuromuscular Depolarizing Agents |
| DB01364 | - | Ephedrine | Vasoconstrictor Agents;Adrenergic Agents;Central Nervous System Stimulants;Sympathomimetics |
| DB01400 | inhibitor | Neostigmine | Parasympathomimetics;Cholinesterase Inhibitors |
| DB01805 | - | Monoisopropylphosphorylserine | |
| DB01928 | - | Huperaine A | Acetylcholinesterase inhibitor |
| DB02166 | - | Propidium | Indicators and Reagents;Acetylcholinesterase inhibitor;Intercalating Agents;Coloring Agents |
| DB02226 | - | 3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-4-Yl]Hexyl]-Phenanthridinium | Acetylcholinesterase inhibitor |
| DB02343 | - | 3,6,9,12,15-Pentaoxaheptadecane | |
| DB02404 | - | 1-Deoxy-1-Thio-Heptaethylene Glycol | Acetylcholinesterase inhibitor |
| DB02575 | - | Tetraethylene Glycol | |
| DB02673 | - | (4ar,6s,8ar)-11-[8-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Octyl]-6-Hydroxy-3-Methoxy-5,6,9,10-Tetrahydro-4ah-[1]Benzofuro[3a,3,2-Ef][2]Benzazepin-11-Ium | Acetylcholinesterase inhibitor |
| DB02825 | - | Methylphosphonic Acid Ester Group | Acetylcholinesterase inhibitor |
| DB03005 | - | 3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-5-Yl]Hexyl]-Phenanthridinium | Acetylcholinesterase inhibitor |
| DB03128 | - | Acetylcholine | Vasodilator Agents;Cholinergic Agents;Acetylcholinesterase inhibitor |
| DB03283 | - | beta-L-fucose | |
| DB03359 | - | M-(N,N,N-Trimethylammonio)-2,2,2-Trifluoro-1,1-Dihydroxyethylbenzene | Acetylcholinesterase inhibitor |
| DB03740 | - | 2-(Acetylamino)-2-Deoxy-a-D-Glucopyranose | |
| DB03814 | - | 2-(N-Morpholino)-Ethanesulfonic Acid | |
| DB03965 | - | Fucose | |
| DB04021 | - | MF268 | Acetylcholinesterase inhibitor |
| DB04114 | - | 3-Chloro-9-Ethyl-6,7,8,9,10,11-Hexahydro-7,11-Methanocycloocta[B]Quinolin-12-Amine | Acetylcholinesterase inhibitor |
| DB04390 | - | Methyl Phosphinic Acid | Acetylcholinesterase inhibitor |
| DB04556 | - | 3-[(1s)-1-(Dimethylamino)Ethyl]Phenol | Acetylcholinesterase inhibitor |
| DB04614 | - | (R)-tacrine(10)-hupyridone | |
| DB04615 | - | (S)-tacrine(10)-hupyridone | |
| DB04616 | - | TACRINE(8)-4-AMINOQUINOLINE | |
| DB04617 | - | (9S)-9-[(8-AMMONIOOCTYL)AMINO]-1,2,3,4,9,10-HEXAHYDROACRIDINIUM | |
| DB07555 | - | 1-(2-nitrophenyl)-2,2,2-trifluoroethyl]-arsenocholine | |
| DB07701 | - | 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE | |
| DB07756 | - | 1-[3-({[(4-AMINO-5-FLUORO-2-METHYLQUINOLIN-3-YL)METHYL]THIO}METHYL)PHENYL]-2,2,2-TRIFLUOROETHANE-1,1-DIOL | |
| DB07822 | - | (1R)-1,2,2-TRIMETHYLPROPYL (S)-METHYLPHOSPHINATE | |
| DB07846 | - | 1S,3AS,8AS-TRIMETHYL-1-OXIDO-1,2,3,3A,8,8A-HEXAHYDROPYRROLO[2,3-B]INDOL-5-YL 2-ETHYLPHENYLCARBAMATE | |
| DB08167 | - | 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM | |
| DB08357 | - | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE | |
| DB08615 | - | 2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM |
| No data |
| No data |
| No data |