AutismKB 2.0

Annotation Detail for MMP11


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Basic Information Top
Gene Symbol:MMP11 ( SL-3,ST3,STMY3 )
Gene Full Name: matrix metallopeptidase 11 (stromelysin 3)
Band: 22q11.23
Quick LinksEntrez ID:4320; OMIM: 185261; Uniprot ID:MMP11_HUMAN; ENSEMBL ID: ENSG00000099953; HGNC ID: 7157
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1893Esotropia
1934Cancer
1954Stroke
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000079 Acetaldehyde Acetaldehyde results in increased expression of MMP11 mRNAincreases expression 11978551
D000079 Acetaldehyde JUN protein promotes the reaction [Acetaldehyde results in increased expression of MMP11 mRNA]increases expression|increases reaction 11978551
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MMP11 mRNAaffects expression 16483693
D001151 Arsenic Arsenic affects the expression of MMP11 mRNAaffects expression 18315880
C006780 bisphenol A bisphenol A inhibits the reaction [Triiodothyronine results in increased expression of MMP11 mRNA]decreases reaction|increases expression 19228888
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of MMP11 mRNAdecreases expression 12419474
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of MMP11 mRNAincreases expression 15056808
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of MMP11 mRNAincreases expression 15766595
D004958 Estradiol [Progesterone co-treated with Estradiol] results in decreased expression of MMP11 mRNAaffects cotreatment|decreases expression 17404688
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of MMP11 mRNAaffects expression 17351261
D005419 Flavonoids Flavonoids results in increased expression of MMP11 mRNAincreases expression 18035473
D006861 Hydrogen Peroxide Hydrogen Peroxide results in decreased expression of MMP11 mRNAdecreases expression 12419474
D007213 Indomethacin Indomethacin results in increased expression of MMP11 mRNAincreases expression 16771604
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of MMP11 mRNAdecreases expression 12057914
D010126 Ozone Ozone results in decreased expression of MMP11 mRNAdecreases expression 16330353
16716893
D011374 Progesterone [Progesterone co-treated with Estradiol] results in decreased expression of MMP11 mRNAaffects cotreatment|decreases expression 17404688
D011374 Progesterone Progesterone results in decreased expression of MMP11 mRNAdecreases expression 17404688
D011374 Progesterone Progesterone affects the expression of MMP11 mRNAaffects expression 17251523
D011374 Progesterone Progesterone results in increased expression of MMP11increases expression 17510236
C017947 sodium arsenite sodium arsenite results in decreased expression of MMP11 mRNAdecreases expression 16014739
D014284 Triiodothyronine bisphenol A inhibits the reaction [Triiodothyronine results in increased expression of MMP11 mRNA]decreases reaction|increases expression 19228888
D014284 Triiodothyronine Triiodothyronine results in increased expression of MMP11 mRNAincreases expression 19228888
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.5518287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9417505938
MESH:D055371 Acute Lung Injury Lipopolysaccharides 4.0118653653 11850527
MESH:D000230 Adenocarcinoma Estradiol 7.0811473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 7.0814692618
MESH:D000230 Adenocarcinoma Indomethacin 7.0816537180
MESH:D000236 Adenoma Indomethacin 3.4411497255
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.7015276417
MESH:D018246 Adrenocortical Adenoma Arsenic 13.7917306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 13.7916712894 17306315
MESH:D016301 Alveolar Bone Loss Indomethacin 5.3717225004
MESH:D000544 Alzheimer Disease Indomethacin 4.4217627676 15579461
MESH:D000544 Alzheimer Disease Ozone 4.4215513908
MESH:D000686 Amyloidosis Diethylstilbestrol 4.4615469931
MESH:D001014 Aortic Aneurysm Indomethacin 4.8310231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.8610388637
MESH:D020261 Arsenic Poisoning Arsenic 2.8612569548 16835338 16251483 18414634
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4511256880
MESH:D018771 Arthralgia Indomethacin 5.172160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6515885639
MESH:D001172 Arthritis, Rheumatoid Indomethacin 4.8611248219
MESH:D001172 Arthritis, Rheumatoid Ozone 4.8615570426
MESH:D001249 Asthma Acetaldehyde 5.429600491
MESH:D001249 Asthma Ozone 5.4216373670 17854713
MESH:D050197 Atherosclerosis Arsenic 3.2419371607 12928151
MESH:D001477 Bartter Syndrome Indomethacin 4.9710684365
MESH:D001862 Bone Resorption bisphenol A 3.8411985600
MESH:D001929 Brain Edema Indomethacin 5.0211481608
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.3417868700
MESH:D001930 Brain Injuries Progesterone 4.2415845082 15380490 15665606
MESH:D002545 Brain Ischemia Indomethacin 4.4112524144
MESH:D001943 Breast Neoplasms bisphenol A 2.3517123778
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.3515324884 17129689
MESH:D001943 Breast Neoplasms Estradiol 2.3518497071 17289903 19861407 12948864 17261762 16675129 14630087 17018787
MESH:D001943 Breast Neoplasms Indomethacin 2.3517401462
MESH:D001943 Breast Neoplasms Progesterone 2.3515562024 17614352 16175315
MESH:D016535 Bronchial Hyperreactivity Ozone 3.6614754758 18417511 17626835 15516495 16777450 18315731 19059883
MESH:D002056 Burns Indomethacin 4.6910459503
MESH:D002100 Cachexia Indomethacin 12.3715141370 16537180 15625704 11239499
MESH:D002100 Cachexia Ozone 12.3716183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4516111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.773786805 15700767 18705752 16050911 16011737 15721981 16097048 15673190 16124888 16227642 16192424 10355542
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.5815504454 17687452
MESH:D006528 Carcinoma, Hepatocellular Arsenic 11.3717306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 11.3718788625
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 11.3715948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.3716924424
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 11.3716391822
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 11.3716507464 17306315 15276417
MESH:D002278 Carcinoma in Situ bisphenol A 4.9817123778
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.7211053908
MESH:D018276 Carcinoma, Medullary Indomethacin 5.3411352223 14736730 18791128
MESH:D002289 Carcinoma, Non-Small-Cell Lung marker/mechanism 10741738
MESH:D002292 Carcinoma, Renal Cell Indomethacin 3.3617341418
MESH:D002294 Carcinoma, Squamous Cell Arsenic 7.6418922899 15504454 17687452
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 7.6412636206 15482327
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 7.6418572023
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.0618640142
MESH:D002310 Cardiomyopathy, Alcoholic Acetaldehyde 6.4810525098
MESH:D002318 Cardiovascular Diseases Arsenic 7.5315738583 19152805 17938729
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 7.5316936243
MESH:D002340 Carotid Artery Diseases Arsenic 4.2916973168 18022660
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.6918566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 6.6919524636 20056578
MESH:D002764 Cholecystitis Indomethacin 5.1711181007
MESH:D002779 Cholestasis Ethinyl Estradiol 2.8617681005 15861022 16919318 17110522 16105132 17333356 11677210
MESH:D003110 Colonic Neoplasms Indomethacin 2.5915963497 11260862 15786552 15637740 15625704 15936596
MESH:D015179 Colorectal Neoplasms Indomethacin 2.3512606626 18059344 17054584 11197048
MESH:D018352 Coronavirus Infections Indomethacin 5.7217302372
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.5416002989 12952375
MESH:D003928 Diabetic Nephropathies Estradiol 3.3919279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.4817187935
MESH:D003967 Diarrhea Indomethacin 3.787907874 7237001
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 2.0419085960 6884620 9327722 7120509 2869522 10092053 15968718 21278145 7440962 3786805 16177239 15998439 16227642 11566570 17522070 15027814 10915739 7179309 4309450 19336974 6623471 3732212
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 5.1417190690 18043480 12774134 18446180 16133044 16326151
MESH:D004381 Duodenal Ulcer Indomethacin 4.1210671773 11991626 17329845 16699067 17045617 17351913 11535926 11595415 17151854 17202747 11595431
MESH:D004487 Edema Indomethacin 3.4816100529 10653021 7907874 19703484 7990266 8985016 8273558
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.9812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 8.9817692515
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.6816402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 7.5016804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 7.5019148513 11473722 18566989
MESH:D004715 Endometriosis Indomethacin 9.2815652904
MESH:D004715 Endometriosis Progesterone 9.2816134523
MESH:D019446 Endotoxemia Indomethacin 10.6218509659
MESH:D019446 Endotoxemia Lipopolysaccharides 10.6217637181 15328337 15821434
MESH:D004751 Enteritis Indomethacin 4.7517763956 10567023 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.9717980183
MESH:D004802 Eosinophilia Indomethacin 4.0411298111
MESH:D004938 Esophageal Neoplasms Indomethacin 2.8011005569
MESH:D005234 Fatty Liver Carbon Tetrachloride 7.6316239168 19224547 15959796 17595544 12631006 61145 16045604 12795759
MESH:D005234 Fatty Liver Ethinyl Estradiol 7.6315345470
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.6415751030 16513791 16002989 16611131 16534752
MESH:D005334 Fever Indomethacin 9.2910431976 11852909 17627676
MESH:D005334 Fever Lipopolysaccharides 9.299205823 11852909
MESH:D005354 Fibrosarcoma Indomethacin 4.8810962813
MESH:D005355 Fibrosis Carbon Tetrachloride 8.9718705752
MESH:D005355 Fibrosis Indomethacin 8.9717994277
MESH:D005499 Folliculitis Indomethacin 5.1711298111
MESH:D005534 Foot Diseases Arsenic 5.566392382
MESH:D005756 Gastritis Indomethacin 4.7515046732
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 12.7916452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 12.7916452187
MESH:D005909 Glioblastoma Indomethacin 3.5512870263
MESH:D005910 Glioma Indomethacin 3.2216487511 18371953
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.2711849393
MESH:D006073 Gout Indomethacin 5.3411248219
MESH:D006258 Head and Neck Neoplasms Indomethacin 3.7315482327
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.3616366002
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.5515633222
MESH:D006505 Hepatitis Carbon Tetrachloride 3.5819110552 19900420
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.6615135802
MESH:D006558 Herpes Genitalis Estradiol 5.0315709030
MESH:D006689 Hodgkin Disease sodium arsenite 3.1312676792
MESH:D019584 Hot Flashes Estradiol 3.7517088409
MESH:D006930 Hyperalgesia Indomethacin 3.7512727271
MESH:D034321 Hyperamylasemia Indomethacin 5.7217883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.5216899240
MESH:D006940 Hyperemia Indomethacin 5.0012524144
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.4417050553
MESH:D006949 Hyperlipidemias Indomethacin 4.1417546600
MESH:D006965 Hyperplasia Diethylstilbestrol 4.4212960047 14722030
MESH:D006973 Hypertension Arsenic 2.8616076760 9931084 11953799
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.0715338365
MESH:D006987 Hypesthesia Arsenic 5.5616093927
MESH:D007021 Hypospadias Diethylstilbestrol 11.2016002989
MESH:D007021 Hypospadias Ethinyl Estradiol 11.2016569931 16945680
MESH:D007077 Ileal Diseases Indomethacin 5.0218306037 10574470
MESH:D007079 Ileitis Indomethacin 5.3410651667 16133968 10647630
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.3716133044
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.3915869954
MESH:D007246 Infertility Diethylstilbestrol 4.3415036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.5917937319
MESH:D007248 Infertility, Male sodium arsenite 6.5912646999 15346721
MESH:D007249 Inflammation Flavonoids 11.9617296493
MESH:D007249 Inflammation Indomethacin 11.967812673 3291741 12568917
MESH:D007249 Inflammation Lipopolysaccharides 11.9617237260 9205823 12878042 17963957 17255318
MESH:D007249 Inflammation Progesterone 11.9615869954
MESH:D007333 Insulin Resistance bisphenol A 7.3916393666
MESH:D007333 Insulin Resistance Estradiol 7.3916393666 16627594
MESH:D007410 Intestinal Diseases Indomethacin 4.3117994277 11855677 11713966 11686837 17329856 15831440 18236018 15610444 10210152
MESH:D019586 Intracranial Hypertension Indomethacin 5.3715241188
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.6117255318
MESH:D007579 Jejunal Diseases Indomethacin 5.0216133968 10574470 18306037
MESH:D007642 Keratosis Arsenic 4.9816930632 12749816
MESH:D007674 Kidney Diseases Estradiol 10.1115618244
MESH:D007674 Kidney Diseases Indomethacin 10.1117190690
MESH:D007674 Kidney Diseases sodium arsenite 10.1120008137
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 4.2516518626
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 7.4816762066 14681315 15003126
MESH:D007680 Kidney Neoplasms Estradiol 7.4815610895
MESH:D007859 Learning Disorders Diethylstilbestrol 4.0517184923
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.8810320625 12228301 11703811
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.9110785260 16572323 15631656
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 2.6318360721
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.5417339181
MESH:D007964 Leukocytosis Indomethacin 5.3716537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.7217980183
MESH:D007970 Leukopenia Lipopolysaccharides 4.6915821434
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.7211479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.8017157831 17334410 21278145 16943688 16221502 11408273 11903743 17174718 16239168
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 5.0017721639 15959796 12667390 14620537 16033810 18277467 17631135 17823541 18166357 18376398 16027843 16015684 10355542 14748882 18339082 15925388 16097048 18472332 18187930 17869086 15362042 17761835 18420326 15931870 18481824 17714472 15123356 18251166 17766677 16011737 16248980 17922224 18279442 14512876 17565644 17481882 12609069 18006644 17900296 15052691 13678700 14716496 18395095 17557913 12445421 16136751 18210741 12649538 12632512 17805973 16192424 12632514 14724832 16638106 17944888 15673190 14716833 12445418 18317297 12898905 16116963 12666154 18705752 15338365 15057751 15730626 18429990 18054572 18205269 17976157 17640975 17708605 11481614 12389079 15876570 18412020 20821823 12546737 12958196 18472094 15996030 17698563 17525996 15370692 18395914 15818738 18156304 18263696 18418968 15650968 12741479 15893842 12586293
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 5.0014659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 5.0018194892
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 5.0012878042
MESH:D008107 Liver Diseases Arsenic 4.2211134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.2215720792 16246199 15830285 17285989 16964402
MESH:D017093 Liver Failure Carbon Tetrachloride 4.1515123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.6714706259 16899240
MESH:D008113 Liver Neoplasms Arsenic 10.7016368122
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 10.7019294768
MESH:D008113 Liver Neoplasms Diethylstilbestrol 10.7016712894 15890375
MESH:D008113 Liver Neoplasms sodium arsenite 10.7016712894 15276417
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.6012014681 15583823
MESH:D008171 Lung Diseases Ozone 7.4719066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 7.4719095001
MESH:D055370 Lung Injury Lipopolysaccharides 9.1921114838
MESH:D055370 Lung Injury Ozone 9.1920417186
MESH:D008175 Lung Neoplasms Acetaldehyde 6.6217372256
MESH:D008175 Lung Neoplasms Arsenic 6.6219168569 17306315 17976673
MESH:D008175 Lung Neoplasms Indomethacin 6.6216537180 11497255 11053908
MESH:D008175 Lung Neoplasms Ozone 6.628597069 7614698
MESH:D008175 Lung Neoplasms sodium arsenite 6.6216712894 17077188 17306315 19931552 15276417
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.1415166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.4615700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.5216002989
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 6.0111408345 11807958 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 6.0111408345 17203775
MESH:D020149 Manganese Poisoning Estradiol 4.4819453300
MESH:D008545 Melanoma sodium arsenite 2.0319082730 16487513
MESH:D008679 Metaplasia Ozone 5.1110496685
MESH:D008881 Migraine Disorders Indomethacin 3.6611903285
MESH:D009062 Mouth Neoplasms Indomethacin 3.9712636206
MESH:D017202 Myocardial Ischemia Arsenic 3.9615371236
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.2616810080
MESH:D009362 Neoplasm Metastasis Indomethacin 3.1611053908 11239499 16537180
MESH:D009369 Neoplasms Diethylstilbestrol 5.2115313581
MESH:D009369 Neoplasms sodium arsenite 5.2111559025
MESH:D009374 Neoplasms, Experimental Indomethacin 9.2315625704 10663608
MESH:D009374 Neoplasms, Experimental sodium arsenite 9.2320056578
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7217289903
MESH:D009421 Nervous System Malformations bisphenol A 16.3911399458 16427766
MESH:D009421 Nervous System Malformations Diethylstilbestrol 16.3911399458
MESH:D009421 Nervous System Malformations Estradiol 16.3911399458 16427766
MESH:D009436 Neural Tube Defects Arsenic 7.4116620997
MESH:D009436 Neural Tube Defects sodium arsenite 7.4112854658
MESH:D019636 Neurodegenerative Diseases Indomethacin 3.9212349958
MESH:D020078 Neurogenic Inflammation Arsenic 4.3617056641
MESH:D007752 Obstetric Labor, Premature Indomethacin 5.176374098
MESH:D010003 Osteoarthritis Indomethacin 3.657009135
MESH:D010049 Ovarian Diseases bisphenol A 4.9811985600
MESH:D010051 Ovarian Neoplasms Arsenic 11.2717306315
MESH:D010051 Ovarian Neoplasms Estradiol 11.2719401270
MESH:D010051 Ovarian Neoplasms Progesterone 11.2716525653 17393432
MESH:D010051 Ovarian Neoplasms sodium arsenite 11.2717306315 15276417
MESH:D010146 Pain Indomethacin 3.4417627676 13679232 17440234 3291741
MESH:D010149 Pain, Postoperative Indomethacin 4.6818702446 12538197
MESH:D010195 Pancreatitis Indomethacin 3.9015028970 17883296
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6711578682
MESH:D010212 Papilloma Hydrogen Peroxide 4.0712065085
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.7216537180
MESH:D020734 Parkinsonian Disorders Indomethacin 4.1012349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.7211903285
MESH:D010437 Peptic Ulcer Indomethacin 5.1411148446
MESH:D010518 Periodontitis Indomethacin 4.9117225004
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.1616093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.9815371236 6392382 16905509
MESH:D010538 Peritonitis Ozone 4.1216369182
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.1714722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.6615687265 16977796
MESH:D011014 Pneumonia Lipopolysaccharides 11.0812224865 11605937
MESH:D011014 Pneumonia Ozone 11.0818007984 18929643 18381685
MESH:D047928 Premature Birth Indomethacin 5.1117000239
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 9.8210548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 9.8217184923
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 10.4920887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 10.4920887781
MESH:D011471 Prostatic Neoplasms Arsenic 1.8716140617
MESH:D011471 Prostatic Neoplasms bisphenol A 1.8716740699
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 1.8715046698 15846301 17136230
MESH:D011471 Prostatic Neoplasms Estradiol 1.8716740699
MESH:D011471 Prostatic Neoplasms sodium arsenite 1.8716039940
MESH:D011507 Proteinuria Arsenic 9.4221343184
MESH:D011507 Proteinuria Indomethacin 9.4211849393
MESH:D011537 Pruritus Ethinyl Estradiol 3.3016919318 15861022
MESH:D011629 Puberty, Precocious bisphenol A 4.7810548101
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.7210835634
MESH:D012220 Rhinitis Acetaldehyde 4.7317050345
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.8518045962
MESH:D012871 Skin Diseases Arsenic 2.7419834688 16702368 17548696 17938729 17050553 16353154 17453740 18709164 15952646 6392382 16759981
MESH:D012878 Skin Neoplasms Arsenic 13.5617976673 15504454 17029826 19538983 16251483 17050553
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 13.5612065085
MESH:D012878 Skin Neoplasms sodium arsenite 13.5619524636 18572023
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 13.568532709
MESH:D013088 Spermatocele Diethylstilbestrol 11.7216002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 11.7216709447
MESH:D013119 Spinal Cord Injuries Progesterone 4.2715862959 16503802
MESH:D016135 Spinal Dysraphism sodium arsenite 3.7812854658
MESH:D013272 Stomach Diseases Indomethacin 4.4118545984 17160473 17207306 10486359 16184426 10215738 18209964 15038085 16280098 10192188 15472012 17638125 16113693
MESH:D013274 Stomach Neoplasms Indomethacin 2.3515609394
MESH:D013276 Stomach Ulcer Indomethacin 3.5716150113 15255614 16755016 12498302 18543354 14567935 17977527 18237397 16397915 17657623 10423059 18193104 12077510 18087811 17918041 11595431 1323529 12467913 17895592 12787963 10750652 11145282 11595415 18209962 15104355 18181030 17135157 16169175 18431645 16934674 11906479 11523592 17627676 18299717 10878458 11729361 15138204 18726076 16631530 17654042 16252198 12500499
MESH:D019966 Substance-Related Disorders bisphenol A 3.9716045194 16684133
MESH:D013921 Thrombocytopenia Lipopolysaccharides 4.1515821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1315669648
MESH:D013964 Thyroid Neoplasms Indomethacin 3.5711352223 14736730 18791128
MESH:D013978 Tibial Fractures Estradiol 4.6919048282
MESH:D014456 Ulcer Indomethacin 4.8817380554 10574470
MESH:D001749 Urinary Bladder Neoplasms Arsenic 8.4018640142 15987713 19429237 11144890 17306315 17976673 19322015
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 8.4016452187 16712894 17306315
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.4016712894 16452187 17306315 11723127
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 9.4816175088
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 9.4811813266
MESH:D014591 Uterine Diseases bisphenol A 13.8214652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 13.8214652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 9.4216690809 15809267
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.4214692618
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.4216002989 16513791
MESH:D014652 Vascular Diseases Arsenic 11.8217056641
MESH:D014652 Vascular Diseases sodium arsenite 11.8217056641
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5215869587 14671159
MESH:D014839 Vomiting Indomethacin 4.7511897121
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB00786 antagonist Marimastat Antineoplastic Agents;Enzyme Inhibitors
DB04318 - 1-Benzyloxycarbonylamino-2-Phenyl-Ethyl)-{2-[1-Carbamoyl-2-(1h-Indol-3-Yl)-Ethylcarbamoyl]-5-Phenyl-Pentyl}-Phosphinic Acid
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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