AutismKB 2.0

Annotation Detail for MOV10


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Basic Information Top
Gene Symbol:MOV10 ( DKFZp667O1423,FLJ32791,KIAA1631,fSAP113,gb110 )
Gene Full Name: Mov10, Moloney leukemia virus 10, homolog (mouse)
Band: 1p13.2
Quick LinksEntrez ID:4343; OMIM: 610742; Uniprot ID:MOV10_HUMAN; ENSEMBL ID: ENSG00000155363; HGNC ID: 7200
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C026137 3-hydroxyacetanilide 3-hydroxyacetanilide results in decreased expression of MOV10 mRNAdecreases expression 18544908
D000082 Acetaminophen Acetaminophen results in decreased expression of MOV10 mRNAdecreases expression 18544908
C053342 brevetoxin brevetoxin analog results in increased expression of MOV10 mRNAincreases expression 14529743
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of MOV10 mRNAincreases expression 14729362
15003993
D016572 Cyclosporine Cyclosporine results in decreased expression of MOV10 mRNAdecreases expression 20106945
C044361 M-VAC protocol MOV10 protein results in decreased susceptibility to M-VAC protocoldecreases response to substance 15814643
D015215 Zidovudine [Zidovudine co-treated with IFNA1 protein] results in increased expression of MOV10 mRNAaffects cotreatment|increases expression 20370541
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 5.189612607
MESH:D000799 Angioedema Acetaminophen 4.2910982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.403084413
MESH:D002386 Cataract Acetaminophen 2.7310977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.7112371664
MESH:D002779 Cholestasis Cyclosporine 3.1219486331
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6517562736 19085960 12594235 11834606 11739529 16177239 12153990 11421492 10774834 16081117 14550746 12705907 16393943 11287661 12540782 14725611 11743745 19739265 19420014 17522070 2444490 16781746 12392966 16227642 19923254 10915739 19370779 19416960 16485898 11461765 15619225 18071297 15968718 10663392 19164858 11529661 18713872 14986274 16109766 17906064 12958197
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.5419426721
MESH:D004362 Drug Toxicity Zidovudine 4.2115040536
MESH:D005234 Fatty Liver Cyclosporine 8.9319224547
MESH:D005234 Fatty Liver Zidovudine 8.9318299183
MESH:D005355 Fibrosis Cyclosporine 3.5012168785 12639820
MESH:D005756 Gastritis Acetaminophen 4.1216983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.628708960
MESH:D006402 Hematologic Diseases Zidovudine 5.0212579204
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.8215720958
MESH:D015658 HIV Infections Zidovudine 3.6211363243 17358032 20032539 11698656 11141242
MESH:D006930 Hyperalgesia Acetaminophen 2.9216870215
MESH:D006973 Hypertension Cyclosporine 2.1810903974
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.8815604871
MESH:D007674 Kidney Diseases Acetaminophen 6.2815629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 6.2818776723 8314463 10903974
MESH:D007680 Kidney Neoplasms Cyclosporine 8.3612371664
MESH:D007680 Kidney Neoplasms Zidovudine 8.3612579204
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 4.6920370541
MESH:D008107 Liver Diseases Acetaminophen 1.6812587719 19784758 16611625 19460945 11587558 19014921 16610002 12969438
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5016871587 17185352
MESH:D008175 Lung Neoplasms Zidovudine 2.4818800350
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9319513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.2316801185
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 6.2817358032
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.8817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5319348381 18481113
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1018514411
MESH:D010146 Pain Acetaminophen 2.6216870215
MESH:D011230 Precancerous Conditions Cyclosporine 3.4712371664
MESH:D011565 Psoriasis Cyclosporine 2.3016882103
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 2.808532709
MESH:D013274 Stomach Neoplasms Zidovudine 2.4817696246
MESH:D014571 Urologic Neoplasms M-VAC protocol 6.4817933135
MESH:D014581 Urticaria Acetaminophen 3.2810982225
MESH:D014605 Uveitis Cyclosporine 4.431336536
MESH:D014625 Vaginal Neoplasms Zidovudine 5.1212579204
MESH:D014985 Xerophthalmia Cyclosporine 4.8817120751
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018