AutismKB 2.0

Annotation Detail for ASMT


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Basic Information Top
Gene Symbol:ASMT ( ASMTY,HIOMT,HIOMTY )
Gene Full Name: acetylserotonin O-methyltransferase
Band: Xp22.3 and Yp11.3
Quick LinksEntrez ID:438; OMIM: 300015,402500; Uniprot ID:HIOM_HUMAN; ENSEMBL ID: ENSG00000196433; HGNC ID: 750
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-6030serotonin and melatonin biosynthesis
Pathway IDPathway Name
hsa00380Tryptophan metabolism
hsa01100Metabolic pathways
Pathway IDPathway Name
Hormone biosynthesis
Metabolism of amino acids and derivatives
No data
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Related Diseases/Disorders Top
No data
Desease IDDesease Name
1916Pervasive development disorder
1975Congenital heart disease
2124Autistic disorder
No data
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No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ASMT mRNAaffects expression 16483693
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.6518287403
MESH:D001321 Autistic Disorder marker/mechanism 17505466
Pathway ID Pathway Name
REACT:15314 Hormone biosynthesis
KEGG:01100 Metabolic pathways
REACT:13 Metabolism of amino acids and derivatives
KEGG:00380 Tryptophan metabolism
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB01065 - Plenovit Melatonina Antioxidants;Free Radical Scavengers;Anticonvulsants;Adjuvants, Immunologic;Central Nervous System Depressants
Drugbank ID Action Drug Name Description
DB01065 substrate Plenovit Melatonina Antioxidants;Free Radical Scavengers;Anticonvulsants;Adjuvants, Immunologic;Central Nervous System Depressants
No data
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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