AutismKB 2.0

Annotation Detail for ODF3B


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Basic Information Top
Gene Symbol:ODF3B ( ODF3L3 )
Gene Full Name: outer dense fiber of sperm tails 3B
Band: 22q13.33
Quick LinksEntrez ID:440836; OMIM: NA; Uniprot ID:ODF3B_HUMAN; ENSEMBL ID: ENSG00000177989; HGNC ID: 34388
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of ODF3B mRNA]affects reaction|decreases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of ODF3B mRNAdecreases expression 19482888
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of ODF3B mRNAdecreases expression 17884332
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 11.476195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 11.4715322242 11752688 14514962
MESH:D018248 Adenoma, Liver Cell Phenobarbital 13.2617620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 13.2616835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.4511748828
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.5912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.8615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 3.0515746008
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.6620435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.2116835633
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 1.956705139 1701930 17173139 20007298 20935162
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.6016120746 18670907 18850075
MESH:D002493 Central Nervous System Diseases Phenobarbital 5.024080065
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.6316835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.2615668235 8697196 12621046 15340226 16354765
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.5317141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2715322242 10048152 20055451
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7517107852
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 1.6320420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 3.1211462148
MESH:D004421 Dystonia Phenobarbital 4.611851702
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.9211000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.9718230668 16714409 15322242
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.5310568697 9294722
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.873659116
MESH:D004828 Epilepsies, Partial Phenobarbital 4.943922381 11558140
MESH:D004827 Epilepsy Phenobarbital 3.1020417680
MESH:D004832 Epilepsy, Absence Phenobarbital 4.016401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 5.027750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.903659116
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.3811564622
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 4.2211858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.7120067830
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.6610696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.5510048152 11294989
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.8911000095
MESH:D006529 Hepatomegaly Phenobarbital 11.1216109766
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 11.1216120746 15340226 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 5.128697196 16959395 15340226 18606429 16354765
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 2.0418850075 18670907
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 2.0612878042 12200463
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.8916580747
MESH:D008103 Liver Cirrhosis Phenobarbital 3.1221047994
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2512878042
MESH:D008107 Liver Diseases Phenobarbital 2.2519363144
MESH:D008113 Liver Neoplasms Phenobarbital 4.9119482888 8742319 19812893 19073162 15975961 21047994
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.9116984957
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 6.731399818 6150874 18308698 17172636 2563599
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 6.7312151625
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 1.2411884234 19555203
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.4312213967
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 5.3617484760
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.8914600291
MESH:D010018 Osteomalacia Phenobarbital 5.2517016548
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.6216965848
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 5.3212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 4.2318163543
MESH:D011230 Precancerous Conditions Phenobarbital 4.092563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 4.0811399792 11896295 11222880 11118676
MESH:D019310 Pseudolymphoma Phenobarbital 5.5612752131
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.5118990726
MESH:D012640 Seizures Phenobarbital 3.014039156 16876388 11442880 3137016
MESH:D003294 Seizures, Febrile Phenobarbital 5.716407741
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.2316192470
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.9712697716
MESH:D013964 Thyroid Neoplasms Phenobarbital 3.431399818
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.6612125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 5.3215886252
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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