AutismKB 2.0

Annotation Detail for NRARP


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Basic Information Top
Gene Symbol:NRARP ( MGC61598 )
Gene Full Name: NOTCH-regulated ankyrin repeat protein
Band: 9q34.3
Quick LinksEntrez ID:441478; OMIM: NA; Uniprot ID:NRARP_HUMAN; ENSEMBL ID: ENSG00000198435; HGNC ID: 33843
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of NRARP mRNAincreases expression 18648102
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of NRARP mRNAincreases expression 19150397
D004041 Dietary Fats Dietary Fats results in increased expression of NRARP mRNAincreases expression 18042831
D002117 Calcitriol Calcitriol results in decreased expression of NRARP mRNAdecreases expression 16002434
C041786 palm oil palm oil results in increased expression of NRARP mRNAincreases expression 18042831
C006253 pirinixic acid pirinixic acid results in decreased expression of NRARP mRNAdecreases expression 17426115
C017947 sodium arsenite sodium arsenite affects the expression of NRARP mRNAaffects expression 19590694
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.4218653653
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.903712494
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.8816434500
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 5.1415276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.3516712894 17306315
MESH:D001161 Arteriosclerosis Dietary Fats 4.2515238619
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.461440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.4319483382
MESH:D001943 Breast Neoplasms Calcitriol 2.2911237771
MESH:D001943 Breast Neoplasms Dietary Fats 2.2920435547
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 3.143581430 7296757
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 3.1417306315 15276417 16507464
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.787296757
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 5.0311237771
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 5.0318572023
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 12.287505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 12.2820889678
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 12.2820056578 19524636
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 8.529022650 19486331
MESH:D002779 Cholestasis pirinixic acid 8.5219176532
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.1511298694 8156756 11906362 14531868 8970840 2524372 18759878 12868966
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5318249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.792952479 3621924
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 2.0218289764 8291058 9328219 6679447 1440618 9653073 16192314 9022650 6482804 11289319 18648102 7440962 18692083
MESH:D050171 Dyslipidemias Dietary Fats 3.6518367378
MESH:D004487 Edema pirinixic acid 2.7612083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 4.2615138306
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.583581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.5820426865
MESH:D005234 Fatty Liver Dietary Fats 8.6519551842 17967931 19004024 18296743
MESH:D005234 Fatty Liver pirinixic acid 8.6519236843 20131406
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.466705139
MESH:D005355 Fibrosis Dietary Fats 3.8818296743
MESH:D005833 Genital Neoplasms, Female sodium arsenite 5.0816452187
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.347505956
MESH:D006333 Heart Failure pirinixic acid 2.6920558911
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.846705139
MESH:D006529 Hepatomegaly pirinixic acid 3.3518467677 19772884 16221962 19176532
MESH:D006689 Hodgkin Disease sodium arsenite 3.4012676792
MESH:D006937 Hypercholesterolemia Dietary Fats 3.8721332399
MESH:D006943 Hyperglycemia pirinixic acid 3.4520558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.9221332399
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.3015034207
MESH:D007248 Infertility, Male sodium arsenite 3.1615346721 12646999
MESH:D007249 Inflammation Dietary Fats 2.5520412841
MESH:D007333 Insulin Resistance Dietary Fats 7.8218457598 11836018
MESH:D007333 Insulin Resistance pirinixic acid 7.8216306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.468074119 9022650
MESH:D007674 Kidney Diseases sodium arsenite 2.9420008137
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.206582329
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0118296743
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.3515034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms pirinixic acid 4.7820007298 16377806 15890375
MESH:D008113 Liver Neoplasms sodium arsenite 4.7816712894 15276417
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.691399818 598648 3712494 6587162
MESH:D008171 Lung Diseases sodium arsenite 3.3519095001
MESH:D008175 Lung Neoplasms sodium arsenite 1.8916712894 19931552 17077188 15276417 17306315
MESH:D008545 Melanoma sodium arsenite 2.0619082730 16487513
MESH:D009135 Muscular Diseases pirinixic acid 3.8616239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2419151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1616411023
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.563581430
MESH:D009369 Neoplasms pirinixic acid 5.3517405874
MESH:D009369 Neoplasms sodium arsenite 5.3511559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 4.0220056578
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.836679447
MESH:D009436 Neural Tube Defects sodium arsenite 7.8312854658
MESH:D009765 Obesity Dietary Fats 4.6220518802 16723640 11836018 18457598 17217161 19632207 21332399 18674790 20132043
MESH:D009765 Obesity pirinixic acid 4.6220558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.686482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.463988306
MESH:D010051 Ovarian Neoplasms sodium arsenite 2.5015276417 17306315
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.847296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.916228378
MESH:D011470 Prostatic Hyperplasia Calcitriol 5.1815572423
MESH:D011471 Prostatic Neoplasms Calcitriol 3.3418247401 16289102 15754350 12479363 16644109
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.3416039940
MESH:D015427 Reperfusion Injury pirinixic acid 2.5019058328
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.583692021
MESH:D012878 Skin Neoplasms sodium arsenite 2.8119524636 18572023
MESH:D016135 Spinal Dysraphism sodium arsenite 4.0112854658
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.091399818 6587162 6582329 7505956 3712494
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 5.398074119
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 5.3916712894 17306315 16452187 11723127
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 4.0311813266
MESH:D014652 Vascular Diseases sodium arsenite 4.8217056641
MESH:D015430 Weight Gain Dietary Fats 3.9916723640
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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