AutismKB 2.0

Annotation Detail for MYO1B


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Basic Information Top
Gene Symbol:MYO1B ( myr1 )
Gene Full Name: myosin IB
Band: 2q32.3
Quick LinksEntrez ID:4430; OMIM: 606537; Uniprot ID:MYO1B_HUMAN; ENSEMBL ID: ENSG00000128641; HGNC ID: 7596
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
P00044Nicotinic acetylcholine receptor signaling pathway
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of MYO1B mRNAincreases expression 19933214
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of MYO1B mRNAincreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of MYO1B mRNAaffects expression 17562736
D006710 Homocysteine Homocysteine results in decreased expression of MYO1B mRNAdecreases expression 17326132
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MYO1B mRNAaffects expression 16483693
D001151 Arsenic Arsenic results in decreased expression of MYO1B mRNAdecreases expression 19654921
C006632 arsenic trioxide arsenic trioxide results in decreased expression of MYO1B mRNAdecreases expression 15070760
15761015
D002713 Chlorine Chlorine results in increased expression of MYO1B mRNAincreases expression 18636392
D002713 Chlorine [Ozone co-treated with Chlorine] affects the expression of MYO1B mRNAaffects cotreatment|affects expression 18636392
D002995 Clofibric Acid Clofibric Acid affects the expression of MYO1B mRNAaffects expression 17602206
D016572 Cyclosporine Cyclosporine results in decreased expression of MYO1B mRNAdecreases expression 20106945
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of MYO1B mRNAaffects cotreatment|increases expression 19619570
D004958 Estradiol Estradiol results in increased expression of MYO1B mRNAincreases expression 19619570
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of MYO1B mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MYO1B mRNAaffects cotreatment|increases expression 17942748
D008628 Mercury Mercury results in increased expression of MYO1B mRNAincreases expression 16823088
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of MYO1B mRNAincreases expression 17616710
D010126 Ozone [Ozone co-treated with Chlorine] affects the expression of MYO1B mRNAaffects cotreatment|affects expression 18636392
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of MYO1B mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in decreased expression of MYO1B mRNAdecreases expression 20059764
16221962
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in decreased expression of MYO1B mRNA]decreases expression|increases reaction 20059764
C009166 retinol acetate retinol acetate results in increased expression of MYO1B mRNAincreases expression 16772331
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of MYO1B mRNAaffects cotreatment|increases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of MYO1B mRNAincreases expression 19619570
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of MYO1B mRNAaffects binding|increases expression 16214954
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MYO1B mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of MYO1B mRNAincreases expression 18796159
19933214
D014520 Urethane Urethane results in decreased expression of MYO1B mRNAdecreases expression 16289808
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7914514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.5018287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8917505938
MESH:D055371 Acute Lung Injury Chlorine 8.9420601635
MESH:D055371 Acute Lung Injury pirinixic acid 8.9418653653
MESH:D000230 Adenocarcinoma arsenic trioxide 10.0811798837 19825857
MESH:D000230 Adenocarcinoma Estradiol 10.0811473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 10.0814692618
MESH:D000230 Adenocarcinoma Urethane 10.0818316556
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Urethane 5.6515814487
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.963712494
MESH:D000236 Adenoma Urethane 6.966695378 10530776 10822126 17195641 16926031 11497255 17093202
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.7016434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.7016835633
MESH:D018246 Adrenocortical Adenoma Arsenic 5.1617306315
MESH:D000544 Alzheimer Disease Ozone 2.4215513908
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8911748828
MESH:D000799 Angioedema Acetaminophen 3.7910982225
MESH:D020261 Arsenic Poisoning Arsenic 2.8512569548 18414634 16251483 16835338
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4011256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6215885639
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5415570426
MESH:D001249 Asthma Ozone 2.6217854713 16373670
MESH:D050197 Atherosclerosis Arsenic 3.2112928151 19371607
MESH:D001321 Autistic Disorder Acetaminophen 2.3418445737
MESH:D001321 Autistic Disorder Homocysteine 2.3416297937 20468076
MESH:D001321 Autistic Disorder Mercury 2.3417497416
MESH:D001327 Autoimmune Diseases Mercury 4.8116634805
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.961440618 11289319
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 14.9216206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 14.9219483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 14.9212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7215746008
MESH:D001943 Breast Neoplasms Estradiol 1.9512948864 17018787 17289903 17261762 14630087 16675129 19861407 18497071
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9520435547
MESH:D016535 Bronchial Hyperreactivity Ozone 3.6218315731 14754758 15516495 19059883 17626835 16777450 18417511
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.2711589617
MESH:D002100 Cachexia Ozone 4.6816183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4016111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7416835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.5517687452 15504454
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 8.763581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.763084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 8.7617306315 16507464
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 8.7615553829 14691202 15073043 16217749 11135700
MESH:D006528 Carcinoma, Hepatocellular Estradiol 8.7616924424
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.8219014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.647296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.0612490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 2.6717687452 18922899 15504454
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.0218640142
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3318670907 16120746 18850075
MESH:D002311 Cardiomyopathy, Dilated Mercury 3.4310334427
MESH:D002318 Cardiovascular Diseases Arsenic 3.4017938729 19152805 15738583
MESH:D002340 Carotid Artery Diseases Arsenic 4.2518022660 16973168
MESH:D002386 Cataract Acetaminophen 2.5410977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 10.877505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.8712371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 10.8718566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1016835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 18.809022650 19486331
MESH:D002779 Cholestasis Cyclosporine 18.8019486331
MESH:D002779 Cholestasis Ethinyl Estradiol 18.8017333356 16105132 15861022 16919318 11677210 17681005 17110522
MESH:D002779 Cholestasis pirinixic acid 18.8019176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 6.0815668235 15340226 12621046 8697196 16354765
MESH:D002972 Cleft Palate Urethane 6.0812810352
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0014669216 17141729
MESH:D003324 Coronary Artery Disease Homocysteine 3.7316379339
MESH:D023903 Coronary Restenosis arsenic trioxide 4.1212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.4510525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4510048152 20055451 15322242
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.0315213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 6.9812868966 2524372 18759878 14531868 11906362 11298694 8970840 8156756
MESH:D017449 Dermatitis, Allergic Contact Mercury 6.9816823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3918249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.432952479 3621924
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6517107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.3519279558
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.0018692083 1440618 18289764 9653073 9328219 7440962 8291058 11289319 6679447 18648102 6482804 9022650 16192314
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.0018713872 11287661 19420014 15968718 16393943 11461765 11743745 12153990 12392966 16109766 19370779 16781746 11739529 19416960 12594235 10915739 10774834 16227642 11529661 12958197 19164858 16081117 17562736 17906064 16177239 18071297 14550746 12705907 15619225 11421492 2444490 19085960 19923254 14725611 16485898 10663392 12540782 19739265 11834606 17522070 14986274
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.0020420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0419426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7111462148
MESH:D004417 Dyspnea Chlorine 4.5720016425
MESH:D004487 Edema pirinixic acid 6.3312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.3312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8518230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.1212538720
MESH:D016889 Endometrial Neoplasms Estradiol 2.9411473722 18566989 19148513
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.969294722 10568697
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 7.223581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 7.2212903497
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 7.2215878914 15150132 16510608 16805852 15547733 16704527 15547721 15264214 15623463
MESH:D017889 Exfoliation Syndrome Homocysteine 5.6416504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9611564622
MESH:D005234 Fatty Liver arsenic trioxide 18.2315073043
MESH:D005234 Fatty Liver Cyclosporine 18.2319224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 18.2315345470
MESH:D005234 Fatty Liver pirinixic acid 18.2320131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3911858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.966705139
MESH:D005355 Fibrosis Cyclosporine 8.2712639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.2720067830
MESH:D005534 Foot Diseases Arsenic 5.506392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.2016904648
MESH:D005739 Gas Poisoning Chlorine 4.9520016425
MESH:D005756 Gastritis Acetaminophen 3.6216983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.168708960
MESH:D005901 Glaucoma Homocysteine 5.2216504073
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.977505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5410696789
MESH:D006330 Heart Defects, Congenital Homocysteine 6.8319638421
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.8310048152 11294989
MESH:D006331 Heart Diseases Urethane 4.1916046796
MESH:D006333 Heart Failure pirinixic acid 2.5020558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3615720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2711000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.456705139
MESH:D006529 Hepatomegaly pirinixic acid 8.0519176532 19772884 16221962 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.0512621046 16120746 15340226
MESH:D006558 Herpes Genitalis Estradiol 4.9815709030
MESH:D019584 Hot Flashes Estradiol 3.7017088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9916354765 15340226 16959395 18606429 8697196
MESH:D006930 Hyperalgesia Acetaminophen 2.6516870215
MESH:D006943 Hyperglycemia pirinixic acid 3.1220558911
MESH:D020138 Hyperhomocysteinemia Homocysteine 4.6517292331 18234410 17369066
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.3917050553
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.8815034207
MESH:D006973 Hypertension Arsenic 8.4416076760 11953799 9931084
MESH:D006973 Hypertension Cyclosporine 8.4410903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.4418670907 18850075
MESH:D006987 Hypesthesia Arsenic 5.5016093927
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7516945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4012013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4417937319
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.8212878042 12200463
MESH:D007333 Insulin Resistance Estradiol 7.0516627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 7.0516306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.968074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2716580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3915604871
MESH:D007642 Keratosis Arsenic 4.9316930632 12749816
MESH:D007674 Kidney Diseases Acetaminophen 14.1412587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 14.148314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 14.1415618244
MESH:D007674 Kidney Diseases Mercury 14.1417934191
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 12.046582329
MESH:D007680 Kidney Neoplasms Cyclosporine 12.0412371664
MESH:D007680 Kidney Neoplasms Estradiol 12.0415610895
MESH:D007938 Leukemia arsenic trioxide 2.8015070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.7312560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.2416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3814633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.7019077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1316467208 16968895 17050201 19850784 20471514
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 7.6417339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.6417712046 16966277 11468182 11161223 15213294 17217047 19035177 19225113 17107899 15748426 19642359 12679006 17649720 16331271 16823087 15336539 16891316 17869043 19075265 16330433 16112521 12018890 12712474 15622746 9834237
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2916882451
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.159327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 3.3314659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.3315474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.3312878042
MESH:D008107 Liver Diseases Acetaminophen 4.0119784758 16610002 19460945 16611625 12969438 12587719 19014921 11587558
MESH:D008107 Liver Diseases Arsenic 4.0111134558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.1817185352 16871587
MESH:D008113 Liver Neoplasms Arsenic 17.6816368122
MESH:D008113 Liver Neoplasms arsenic trioxide 17.6814682389
MESH:D008113 Liver Neoplasms Clofibric Acid 17.6817602206
MESH:D008113 Liver Neoplasms pirinixic acid 17.6815890375 20007298 16377806
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.6816984957
MESH:D008113 Liver Neoplasms Urethane 17.6816391232 17559639 17093202
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 9.553712494 1399818 6587162 598648
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 9.5520377131
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.5512151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3015213294
MESH:D008171 Lung Diseases Ozone 3.3319066396 8266340
MESH:D055370 Lung Injury Ozone 3.7820417186
MESH:D008175 Lung Neoplasms Arsenic 6.5317306315 17976673 19168569
MESH:D008175 Lung Neoplasms arsenic trioxide 6.5319825857 11798837
MESH:D008175 Lung Neoplasms Ozone 6.538597069 7614698
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.5319555203 11884234
MESH:D008175 Lung Neoplasms Urethane 6.5312765245 11074608 15166089 10822126 11323394 6695378 16926031 16391232 17255336 16337739 16204055 11497255 11992545 11062179 12117781 10530776 10997738 12466968 16007126 15902970 17195641 15136453 11807781 7750092 11893704 16788158 17093202 11544531 16289808 11552296 12957351 10779650 14587096 11307925 11246140
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.5216891317 17203775 11807958 11408345
MESH:D020149 Manganese Poisoning Estradiol 4.4319453300
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5019513568
MESH:D008591 Meningomyelocele Homocysteine 5.4716602021
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7316801185
MESH:D008679 Metaplasia Ozone 5.0510496685
MESH:D009101 Multiple Myeloma arsenic trioxide 3.0619417148 11468182 14977855 15949261 19549372
MESH:D009135 Muscular Diseases pirinixic acid 3.4416239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.6218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.1016105982 16882451
MESH:D009203 Myocardial Infarction Homocysteine 5.9017412321
MESH:D009203 Myocardial Infarction pirinixic acid 5.9019151258
MESH:D017202 Myocardial Ischemia Arsenic 8.8215371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.8212213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.0816810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.0816411023
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.9016624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.443581430
MESH:D009369 Neoplasms pirinixic acid 5.2017405874
MESH:D009369 Neoplasms Urethane 5.2015625555
MESH:D009374 Neoplasms, Experimental Urethane 4.6115582191
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6717289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3917954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2319348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 9.2516427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.2514600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 11.936679447
MESH:D009436 Neural Tube Defects Arsenic 11.9316620997
MESH:D009436 Neural Tube Defects arsenic trioxide 11.9310525206
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8118514411
MESH:D020078 Neurogenic Inflammation Arsenic 4.3117056641
MESH:D009765 Obesity pirinixic acid 1.8020558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.364026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.963988306
MESH:D010051 Ovarian Neoplasms Arsenic 11.1917306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 11.1912452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Estradiol 11.1919401270
MESH:D010051 Ovarian Neoplasms Urethane 11.1916391232
MESH:D010146 Pain Acetaminophen 2.3416870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.5015580305
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6211578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.427296757
MESH:D010235 Paraganglioma arsenic trioxide 4.1019927285
MESH:D010300 Parkinson Disease Homocysteine 3.5516275827
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1912520081
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.1116093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.9315371236 6392382 16905509
MESH:D010538 Peritonitis Ozone 4.0716369182
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.416228378
MESH:D010911 Pituitary Neoplasms Urethane 5.3516391232
MESH:D011014 Pneumonia Ozone 4.3318929643 18381685 18007984
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4918163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.1612371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.1311896295 11118676 11399792 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8220887781
MESH:D011471 Prostatic Neoplasms Arsenic 2.6316140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.6319131511
MESH:D011471 Prostatic Neoplasms Estradiol 2.6316740699
MESH:D011507 Proteinuria Arsenic 3.9421343184
MESH:D011537 Pruritus Ethinyl Estradiol 3.2516919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.2116882103
MESH:D015427 Reperfusion Injury pirinixic acid 2.3519058328
MESH:D012120 Respiration Disorders Chlorine 5.1618579056
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7718990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.323692021
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.9016646077
MESH:D012559 Schizophrenia Homocysteine 3.1016641680
MESH:D012871 Skin Diseases Arsenic 2.7317050553 17453740 16702368 17548696 17938729 15952646 16759981 19834688 6392382 18709164 16353154
MESH:D012878 Skin Neoplasms Arsenic 9.4417029826 17050553 17976673 16251483 15504454 19538983
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.4416192470
MESH:D012878 Skin Neoplasms Urethane 9.4411807781
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8916709447
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.6317007042
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 2.6317575124 12958204
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0915669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8512697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 6.981399818 6582329 3712494 7505956 6587162
MESH:D013964 Thyroid Neoplasms arsenic trioxide 6.9819014326
MESH:D013978 Tibial Fractures Estradiol 4.6319048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.9015213294
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 8.238074119
MESH:D001749 Urinary Bladder Neoplasms Arsenic 8.2319322015 19429237 17976673 15987713 11144890 17306315 18640142
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.2311780464 12845720 12973940 20435036
MESH:D014581 Urticaria Acetaminophen 2.9110982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2314692618
MESH:D014605 Uveitis Cyclosporine 3.931336536
MESH:D014652 Vascular Diseases Arsenic 4.6717056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5412125929
MESH:D019043 Vascular Neoplasms Urethane 5.8610620525
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4814671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1915886252
MESH:D014985 Xerophthalmia Cyclosporine 4.3917120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA31398
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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