AutismKB 2.0

Annotation Detail for MSH4


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Basic Information Top
Gene Symbol:MSH4 ( - )
Gene Full Name: mutS homolog 4 (E. coli)
Band: 1p31.1
Quick LinksEntrez ID:4438; OMIM: 602105; Uniprot ID:MSH4_HUMAN; ENSEMBL ID: ENSG00000057468; HGNC ID: 7327
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2121Ovarian failure
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C006780 bisphenol A bisphenol A results in increased expression of MSH4 mRNAincreases expression 20739668
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D001862 Bone Resorption bisphenol A 4.4911985600
MESH:D001943 Breast Neoplasms bisphenol A 2.4217123778
MESH:D002278 Carcinoma in Situ bisphenol A 6.0817123778
MESH:D007333 Insulin Resistance bisphenol A 3.6116393666
MESH:D009421 Nervous System Malformations bisphenol A 4.7611399458 16427766
MESH:D010049 Ovarian Diseases bisphenol A 6.0811985600
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 5.0410548101
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.8420887781
MESH:D011471 Prostatic Neoplasms bisphenol A 3.3316740699
MESH:D011629 Puberty, Precocious bisphenol A 5.8810548101
MESH:D019966 Substance-Related Disorders bisphenol A 5.0716045194 16684133
MESH:D014591 Uterine Diseases bisphenol A 6.4214652134
Pathway ID Pathway Name
REACT:27271 Meiotic Recombination
REACT:27235 Meiotic Recombination (mouse)
Pharmacogenomics Knowledge Base Top
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018