AutismKB 2.0

Annotation Detail for MSR1


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Basic Information Top
Gene Symbol:MSR1 ( CD204,SCARA1,SR-A,phSR1,phSR2 )
Gene Full Name: macrophage scavenger receptor 1
Band: 8p22
Quick LinksEntrez ID:4481; OMIM: 153622; Uniprot ID:MSRE_HUMAN; ENSEMBL ID: ENSG00000038945; HGNC ID: 7376
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1831Prostate cancer
2053Colon cancer
Desease Name
CHEMDEPENDENCY
prostate cancer
CANCER
smoking cessation
No data
Desease Name
Prostate cancer, hereditary
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C038983 1,3-dimethylthiourea 1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 9614211
D000082 Acetaminophen Acetaminophen affects the expression of MSR1 mRNAaffects expression 17562736
C056165 acetovanillone acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 9614211
C061133 Am 80 Am 80 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 16484594
C061133 Am 80 Am 80 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 16484594
C006632 arsenic trioxide arsenic trioxide results in decreased expression of MSR1 mRNAdecreases expression 20458559
C042138 BCG lipopolysaccharide BCG lipopolysaccharide results in increased expression of MSR1 mRNAincreases expression 10223745
D020122 tert-Butylhydroperoxide MSR1 protein results in decreased susceptibility to tert-Butylhydroperoxidedecreases response to substance 12763022
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased activity of MSR1 proteindecreases activity 12763022
D002330 Carmustine Carmustine results in decreased expression of MSR1 mRNAdecreases expression 15980968
D003513 Cycloheximide Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 9614211
D003676 Deferoxamine Deferoxamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 9614211
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MSR1 mRNAaffects cotreatment|increases expression 17942748
C460864 FSL-1 lipoprotein, synthetic FSL-1 lipoprotein, synthetic results in increased expression of MSR1 mRNAincreases expression 17938187
C460864 FSL-1 lipoprotein, synthetic resveratrol inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased expression of MSR1 mRNA]decreases reaction|increases expression 17938187
D005665 Furosemide Furosemide results in increased expression of MSR1 mRNAincreases expression 16526316
D017665 Hydroxyl Radical Hydroxyl Radical results in decreased degradation of MSR1 mRNAdecreases degradation 9614211
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of MSR1 proteinincreases expression 10223745
C443401 quercetin 3-O-glucuronide quercetin 3-O-glucuronide results in decreased expression of MSR1 mRNAdecreases expression 18199750
C059514 resveratrol resveratrol inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased expression of MSR1 mRNA]decreases reaction|increases expression 17938187
C059514 resveratrol resveratrol results in decreased expression of MSR1 mRNAdecreases expression 16901463
D012402 Rotenone Rotenone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 9614211
D020160 Sodium Benzoate Sodium Benzoate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 9614211
D020160 Sodium Benzoate Sodium Benzoate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form]decreases reaction|increases expression 9614211
C003959 TEMPO TEMPO inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 9614211
C003959 TEMPO TEMPO inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form]decreases reaction|increases expression 9614211
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MSR1 mRNAaffects cotreatment|increases expression 17942748
D013755 Tetradecanoylphorbol Acetate 1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 9614211
D013755 Tetradecanoylphorbol Acetate acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 9614211
D013755 Tetradecanoylphorbol Acetate Am 80 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 16484594
D013755 Tetradecanoylphorbol Acetate Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 9614211
D013755 Tetradecanoylphorbol Acetate Deferoxamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 9614211
D013755 Tetradecanoylphorbol Acetate Rotenone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 9614211
D013755 Tetradecanoylphorbol Acetate Sodium Benzoate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 9614211
D013755 Tetradecanoylphorbol Acetate Sodium Benzoate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form]decreases reaction|increases expression 9614211
D013755 Tetradecanoylphorbol Acetate TEMPO inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 9614211
D013755 Tetradecanoylphorbol Acetate TEMPO inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form]decreases reaction|increases expression 9614211
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNAincreases expression 9614211
16484594
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative formincreases expression 9614211
D013755 Tetradecanoylphorbol Acetate Am 80 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]decreases reaction|increases expression 16484594
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNAincreases expression 16484594
D015054 Zymosan Zymosan results in increased expression of MSR1 mRNAincreases expression 10223745
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7011752688 15322242 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7917505938
MESH:D058186 Acute Kidney Injury resveratrol 3.7116538975
MESH:D055371 Acute Lung Injury Lipopolysaccharides 3.8911850527 18653653
MESH:D000230 Adenocarcinoma arsenic trioxide 4.1611798837 19825857
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.1614692618
MESH:D000236 Adenoma resveratrol 3.2315688382
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.2316835633
MESH:D000544 Alzheimer Disease resveratrol 2.5416162502 16183991
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.5511748828
MESH:D000740 Anemia Zymosan 8.5518664788
MESH:D000799 Angioedema Acetaminophen 3.6910982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.3111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 11.8815885639
MESH:D001169 Arthritis, Experimental resveratrol 11.8817115116
MESH:D001169 Arthritis, Experimental Zymosan 11.8815944321 15142272 17659584 16872482 15188379
MESH:D001172 Arthritis, Rheumatoid Am 80 3.7216819260
MESH:D050197 Atherosclerosis Am 80 11.0216484594
MESH:D050197 Atherosclerosis quercetin 3-O-glucuronide 11.0218199750
MESH:D050197 Atherosclerosis resveratrol 11.0217967414 16873680
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.5016206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.5012125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6715746008
MESH:D002545 Brain Ischemia resveratrol 4.1317600658
MESH:D001932 Brain Neoplasms Carmustine 4.2616187019
MESH:D001943 Breast Neoplasms Deferoxamine 2.0915993339
MESH:D001943 Breast Neoplasms resveratrol 2.0916393696 17651959 17534123
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.0920435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1911589617
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6816835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.473084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 4.4715553829 16217749 11135700 14691202 15073043
MESH:D006528 Carcinoma, Hepatocellular resveratrol 4.4719321006 16227395
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.4416675471
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7219014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9812490120
MESH:D002294 Carcinoma, Squamous Cell resveratrol 4.9116227395
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 4.9118922899
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2816120746 18670907 18850075
MESH:D002318 Cardiovascular Diseases resveratrol 3.3715458977
MESH:D002386 Cataract Acetaminophen 2.4910977129
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0316835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.7615861022 16919318 17110522 17681005 11677210 16105132 17333356
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.048697196 16354765 15340226 12621046 15668235
MESH:D003092 Colitis resveratrol 3.9816474422
MESH:D003110 Colonic Neoplasms resveratrol 2.4316338953
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.5920501625
MESH:D015179 Colorectal Neoplasms resveratrol 2.5916550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9317141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.6616507316
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0412609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.4210525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4210048152 15322242 20055451
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9515213294
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.6416873680
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6317107852
MESH:D003928 Diabetic Nephropathies resveratrol 3.8316286809
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.4111529661 11461765 15619225 10915739 16393943 16781746 2444490 11287661 19923254 11834606 10774834 15968718 16109766 12958197 14550746 16227642 12392966 19416960 19164858 14986274 11743745 19739265 17562736 18071297 11739529 17906064 12594235 11421492 16485898 14725611 19370779 12153990 12540782 16081117 19420014 16177239 18713872 17522070 10663392 19085960 12705907
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.4120420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9519426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6511462148
MESH:D004417 Dyspnea Furosemide 4.7916935035
MESH:D004487 Edema Furosemide 20.2311834646
MESH:D004487 Edema resveratrol 20.238985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 20.2311000095 12711302
MESH:D004487 Edema Tetradecanoylphorbol Acetate 20.238113982 9599246 7812673 15177302 8273558 11698051 16716910
MESH:D004487 Edema Zymosan 20.237907874
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7515322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Am 80 14.7116819260
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 14.7112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 14.7117872969
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.8910568697 9294722
MESH:D019446 Endotoxemia Lipopolysaccharides 4.2417637181 15821434 15328337
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.7017923197
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.2712903497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9011564622
MESH:D005234 Fatty Liver arsenic trioxide 7.2815073043
MESH:D005234 Fatty Liver Ethinyl Estradiol 7.2815345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3111858732
MESH:D005334 Fever Lipopolysaccharides 3.8811852909 9205823
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 2.8020067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1116904648
MESH:D005756 Gastritis Acetaminophen 3.5216983495
MESH:D005909 Glioblastoma Carmustine 3.8316187019
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4410696789
MESH:D034381 Hearing Loss Furosemide 4.7017868369
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2510048152 11294989
MESH:D006333 Heart Failure Furosemide 3.9716845234 12660669 16011733
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.2516366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2011000095
MESH:D006505 Hepatitis Zymosan 4.5519110552
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.7415340226 16120746 12621046
MESH:D006561 Herpes Simplex resveratrol 4.0316876885
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8916354765 8697196 18606429 15340226 16959395
MESH:D006930 Hyperalgesia Acetaminophen 2.5816870215
MESH:D006934 Hypercalcemia Furosemide 4.9317652376
MESH:D053565 Hypercalciuria Furosemide 5.5017652376
MESH:D006937 Hypercholesterolemia resveratrol 3.8717188708
MESH:D006949 Hyperlipidemias resveratrol 3.8916873680
MESH:D006962 Hyperparathyroidism, Secondary Furosemide 5.7215086907
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8518850075 18670907
MESH:D046110 Hypertension, Pregnancy-Induced Furosemide 5.1316612254
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.1717488730
MESH:C537153 Hypomagnesemia primary Furosemide 5.5011041285
MESH:D007019 Hypoproteinemia Furosemide 5.7216096441
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6616569931 16945680
MESH:D007022 Hypotension Furosemide 4.4711041285
MESH:D007024 Hypotension, Orthostatic Furosemide 5.2715811171
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.5017600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.3917937319
MESH:D007249 Inflammation Lipopolysaccharides 15.0712878042 9205823 17237260 17963957 17255318
MESH:D007249 Inflammation resveratrol 15.0716366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 15.0712200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 15.0711698051 7812673 7562506 8273558 15177302
MESH:D007249 Inflammation Zymosan 15.078014878 11289658
MESH:D007251 Influenza, Human resveratrol 4.3916624496
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.4917255318
MESH:D043183 Irritable Bowel Syndrome Zymosan 5.6817553498
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2016580747
MESH:D007674 Kidney Diseases Acetaminophen 6.0312587719 15629191
MESH:D007674 Kidney Diseases Furosemide 6.0311041285
MESH:D007938 Leukemia arsenic trioxide 2.7615070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6617077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.1516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3214633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.6219077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 4.3217050201 20471514 16467208 19850784 16968895
MESH:D015470 Leukemia, Myeloid, Acute Deferoxamine 4.3220368581
MESH:D015473 Leukemia, Promyelocytic, Acute Am 80 12.4116819260 16531727
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 12.4112712474 16823087 9834237 16891316 19225113 17649720 16966277 16112521 15336539 19642359 12018890 17107899 15748426 15213294 16331271 17712046 11161223 19035177 12679006 19075265 16330433 11468182 17869043 15622746 17217047
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 12.4116087638
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2016882451
MESH:D007970 Leukopenia Lipopolysaccharides 4.5515821434
MESH:D008106 Liver Cirrhosis, Experimental 1,3-dimethylthiourea 3.6511682029
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 3.6512878042
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.6512878042
MESH:D008107 Liver Diseases Acetaminophen 1.5912969438 16611625 19460945 11587558 19784758 12587719 19014921 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.1017185352 16871587
MESH:D008113 Liver Neoplasms arsenic trioxide 7.1414682389
MESH:D008113 Liver Neoplasms resveratrol 7.1419812893 19073162 20405173 19321006
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 7.1416984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 5.4920377131
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 5.4912151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2315213294
MESH:D055370 Lung Injury Lipopolysaccharides 3.8621114838
MESH:D008175 Lung Neoplasms arsenic trioxide 3.3819825857 11798837
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.3819555203 11884234
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 3.3811807781
MESH:D016393 Lymphoma, B-Cell resveratrol 4.1617088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.7514749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.0915688416
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 6.1211606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 6.128985016
MESH:D008545 Melanoma Carmustine 3.7212393984
MESH:D008545 Melanoma resveratrol 3.7217992120
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4219513568
MESH:D008659 Metabolic Diseases resveratrol 4.2417112576
MESH:D009101 Multiple Myeloma Am 80 11.7217229644
MESH:D009101 Multiple Myeloma arsenic trioxide 11.7219417148 11468182 14977855 19549372 15949261
MESH:D009101 Multiple Myeloma resveratrol 11.7217935668 17049120 17164350 14749477 16267019 16490592
MESH:D009102 Multiple Organ Failure Zymosan 5.0612130978 15213630 17724436 15259001 15241586 10890648 18160304 12879239 10479408 15834315
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.7217962980
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.0616105982 16882451
MESH:D009203 Myocardial Infarction resveratrol 2.9717188708 17015251 17125593 16317513 16525036 16456233
MESH:D017202 Myocardial Ischemia resveratrol 8.6117125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.6112213967
MESH:D009205 Myocarditis resveratrol 4.6117322642
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.8116624393
MESH:D009374 Neoplasms, Experimental resveratrol 3.858985016
MESH:D009397 Nephrocalcinosis Furosemide 5.7215086907
MESH:D009410 Nerve Degeneration Rotenone 3.7617356569 15790535 18619942
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.0714600291
MESH:D009436 Neural Tube Defects arsenic trioxide 3.0210525206
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.9418514411
MESH:D019636 Neurodegenerative Diseases resveratrol 7.9417652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.2617929310
MESH:D053206 Nocturnal Enuresis Furosemide 5.7217945291
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.1117513867
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.3616624393 19769630 12452020
MESH:D010146 Pain Acetaminophen 2.2716870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 5.3515580305
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 5.3515976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5411578682
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 4.1418922899 8330346 12065085 18404319
MESH:D010235 Paraganglioma arsenic trioxide 4.0219927285
MESH:D010300 Parkinson Disease Rotenone 2.9211445065 18191903 11535288 18619942 16140633 19232380 19114014 16412576 15451049
MESH:D020734 Parkinsonian Disorders Rotenone 3.9415927086 15574749 15795934 18197244
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1012520081
MESH:D010538 Peritonitis Zymosan 4.7319641140 14761945 17826846 18760300 17371808 18977430 15259001 15979727 18557954 11985352 19088179
MESH:D011014 Pneumonia Lipopolysaccharides 4.4012224865 11605937
MESH:D011141 Polyuria Furosemide 5.5017945291
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4118163543
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 9.0816679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.0811896295 11399792 11118676 11222880
MESH:D011471 Prostatic Neoplasms marker/mechanism 16998812
MESH:D011471 Prostatic Neoplasms Am 80 2.8716289102
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.8719131511
MESH:D011471 Prostatic Neoplasms resveratrol 2.8717636462 17718901 17804756 17675339 15767336 16731767
MESH:D011537 Pruritus Ethinyl Estradiol 3.1616919318 15861022
MESH:D011565 Psoriasis Am 80 4.0416819260
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.4316325855
MESH:D015427 Reperfusion Injury Furosemide 6.8916526316
MESH:D015427 Reperfusion Injury resveratrol 6.8916314181 16317513 17520802 17058453 15827377
MESH:D012128 Respiratory Distress Syndrome, Adult Furosemide 4.4712394941 15912074 16096441
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.6310835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6918990726
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.8116646077
MESH:D018805 Sepsis Zymosan 4.5211441115
MESH:D012878 Skin Neoplasms resveratrol 13.038985016 15837718
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 13.038532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 13.0316192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 13.0318404319 11807781 8330346 12065085 8985016
MESH:D013088 Spermatocele Ethinyl Estradiol 3.7916709447
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.8117007042
MESH:D013274 Stomach Neoplasms Furosemide 2.8117052386
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.3516321402
MESH:D013921 Thrombocytopenia Lipopolysaccharides 4.0315821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0215669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7512697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 2.9719014326
MESH:D014062 Tongue Neoplasms resveratrol 4.0816227395
MESH:D016171 Torsades de Pointes arsenic trioxide 3.8115213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.4212845720 20435036 12973940 11780464
MESH:D014581 Urticaria Acetaminophen 2.8310982225
MESH:D002583 Uterine Cervical Neoplasms resveratrol 3.9717473185
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.0114692618
MESH:D014594 Uterine Neoplasms resveratrol 9.0117044934
MESH:D014605 Uveitis Zymosan 5.2511006244
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4412125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4015869587 14671159
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.1517488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1015886252
Pathway ID Pathway Name
KEGG:04145 Phagosome
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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