Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
---|
D000082 |
Acetaminophen |
Acetaminophen affects the expression of MST1R mRNA | affects expression | 17562736
|
D003474 |
Curcumin |
Curcumin inhibits the reaction [RELA protein binds to MST1R promoter] | affects binding|decreases reaction | 18593918
|
D003474 |
Curcumin |
Curcumin inhibits the reaction [RELA protein results in increased expression of MST1R mRNA] | decreases reaction|increases expression | 18593918
|
D003474 |
Curcumin |
Curcumin results in decreased expression of MST1R mRNA | decreases expression | 18593918
|
D003474 |
Curcumin |
Curcumin results in decreased expression of MST1R protein | decreases expression | 18593918
|
C029938 |
nickel sulfate |
nickel sulfate results in decreased expression of MST1R mRNA | decreases expression | 16780908
|
C029938 |
nickel sulfate |
nickel sulfate results in increased expression of MST1R mRNA | increases expression | 16780908
|
C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of MST1R mRNA | affects binding|decreases expression|increases activity | 19710929
|
C020972 |
pyrrolidine dithiocarbamic acid |
pyrrolidine dithiocarbamic acid results in decreased expression of MST1R mRNA | decreases expression | 18593918
|
Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
---|
MESH:D055371 |
Acute Lung Injury |
|
nickel sulfate |
10.52 | 11954676 12718980 16100012 19131640 |
MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
10.52 | 18653653 |
MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.02 | 16434500 |
MESH:D019973 |
Alcohol-Related Disorders |
|
Curcumin |
5.69 | 17887948 |
MESH:D000544 |
Alzheimer Disease |
|
Curcumin |
2.67 | 15590663 |
MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.45 | 10982225 |
MESH:D001172 |
Arthritis, Rheumatoid |
|
Curcumin |
2.80 | 16807698 |
MESH:D050197 |
Atherosclerosis |
|
Curcumin |
3.51 | 18704882 |
MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
MESH:D001327 |
Autoimmune Diseases |
|
Curcumin |
4.98 | 19761891 |
MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.52 | 19483382 |
MESH:D002545 |
Brain Ischemia |
|
Curcumin |
4.87 | 16770732 |
MESH:D001932 |
Brain Neoplasms |
|
Curcumin |
4.28 | 17596214 |
MESH:D001943 |
Breast Neoplasms |
|
Curcumin |
2.71 | 18593918 18462866 19250217 16243823 |
MESH:D002277 |
Carcinoma |
|
Curcumin |
4.12 | 18593918 |
MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
1.40 | 3084413 |
MESH:D002289 |
Carcinoma, Non-Small-Cell Lung |
|
Curcumin |
3.07 | 18414057 |
MESH:D002294 |
Carcinoma, Squamous Cell |
|
Curcumin |
2.84 | 18462866 |
MESH:D002386 |
Cataract |
|
Acetaminophen |
2.77 | 10977129 |
MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.08 | 19176532 |
MESH:D003092 |
Colitis |
|
Curcumin |
4.66 | 16782535 16804969 18200517 |
MESH:D003103 |
Coloboma |
|
Curcumin |
4.92 | 18809619 |
MESH:D003110 |
Colonic Neoplasms |
|
Curcumin |
2.55 | 19359593 16340194 |
MESH:D016510 |
Corneal Neovascularization |
|
Curcumin |
5.38 | 18497527 |
MESH:D017449 |
Dermatitis, Allergic Contact |
|
nickel sulfate |
4.15 | 16780908 11298694 16823706 |
MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.56 | 18249437 |
MESH:D003924 |
Diabetes Mellitus, Type 2 |
|
Curcumin |
2.77 | 18403477 |
MESH:D003928 |
Diabetic Nephropathies |
|
Curcumin |
4.33 | 18204486 |
MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
1.66 | 12540782 12958197 11287661 12705907 16485898 11834606 17562736 10774834 19739265 14725611 11529661 19416960 10915739 18071297 12153990 11461765 19923254 16177239 2444490 16081117 11743745 16227642 19164858 16109766 11739529 11421492 10663392 17522070 16393943 12392966 12594235 14986274 18713872 17906064 14550746 15968718 19370779 16781746 19420014 19085960 15619225 |
MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.71 | 19426721 |
MESH:D004381 |
Duodenal Ulcer |
|
Curcumin |
4.49 | 17351913 |
MESH:D004487 |
Edema |
|
pirinixic acid |
2.85 | 12083418 |
MESH:D005234 |
Fatty Liver |
|
Curcumin |
9.13 | 19297423 |
MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
9.13 | 19236843 20131406 |
MESH:D005355 |
Fibrosis |
|
Curcumin |
4.47 | 18705752 |
MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.29 | 16983495 |
MESH:D005770 |
Gastrointestinal Neoplasms |
|
Curcumin |
5.18 | 18462866 |
MESH:D005909 |
Glioblastoma |
|
Curcumin |
3.69 | 17596214 |
MESH:D006258 |
Head and Neck Neoplasms |
|
Curcumin |
3.88 | 18829502 18462866 |
MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.73 | 20558911 |
MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.48 | 19176532 16221962 19772884 18467677 |
MESH:D015417 |
Hereditary Sensory and Motor Neuropathy |
|
Curcumin |
5.52 | 17701891 |
MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.99 | 16870215 |
MESH:D006937 |
Hypercholesterolemia |
|
Curcumin |
4.43 | 18704882 |
MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.53 | 20558911 |
MESH:D007249 |
Inflammation |
|
Curcumin |
3.05 | 18403477 16956363 17151092 |
MESH:D015212 |
Inflammatory Bowel Diseases |
|
Curcumin |
3.32 | 18200517 18596194 |
MESH:D007251 |
Influenza, Human |
|
pyrrolidine dithiocarbamic acid |
6.17 | 18473937 |
MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.85 | 16306350 |
MESH:D007414 |
Intestinal Neoplasms |
|
Curcumin |
4.57 | 10783313 |
MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.38 | 12587719 15629191 |
MESH:D007889 |
Leiomyoma |
|
Curcumin |
4.98 | 18555241 |
MESH:D007938 |
Leukemia |
|
Curcumin |
3.39 | 18462866 |
MESH:D015459 |
Leukemia-Lymphoma, Adult T-Cell |
|
Curcumin |
4.58 | 16106398 |
MESH:D015458 |
Leukemia, T-Cell |
|
Curcumin |
5.20 | 16106398 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Curcumin |
3.90 | 17355460 18006644 18705752 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
3.90 | 15474484 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pyrrolidine dithiocarbamic acid |
3.90 | 15078482 |
MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
4.34 | 16611625 12969438 11587558 19460945 12587719 19014921 16610002 19784758 |
MESH:D008107 |
Liver Diseases |
|
Curcumin |
4.34 | 16956363 |
MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.58 | 16871587 17185352 |
MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.92 | 16377806 20007298 15890375 |
MESH:D055370 |
Lung Injury |
|
pyrrolidine dithiocarbamic acid |
5.47 | 16129981 |
MESH:D008175 |
Lung Neoplasms |
|
Curcumin |
2.28 | 16243823 19359593 18462866 |
MESH:D008223 |
Lymphoma |
|
Curcumin |
3.83 | 18462866 |
MESH:D016399 |
Lymphoma, T-Cell |
|
Curcumin |
5.18 | 16173963 |
MESH:D008545 |
Melanoma |
|
Curcumin |
2.45 | 18462866 17885582 |
MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.05 | 19513568 |
MESH:D008569 |
Memory Disorders |
|
Curcumin |
4.59 | 17263510 |
MESH:D009101 |
Multiple Myeloma |
|
Curcumin |
3.76 | 19372569 |
MESH:D009134 |
Muscular Atrophy, Spinal |
|
Curcumin |
5.46 | 17962980 |
MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
3.99 | 16239165 |
MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.26 | 19151258 |
MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.22 | 16411023 |
MESH:D009361 |
Neoplasm Invasiveness |
|
Curcumin |
4.81 | 18495463 |
MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.09 | 17405874 |
MESH:D009376 |
Neoplasms, Hormone-Dependent |
|
Curcumin |
5.14 | 12497104 |
MESH:D009423 |
Nervous System Neoplasms |
|
Curcumin |
6.24 | 18462866 |
MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.18 | 18514411 |
MESH:D009765 |
Obesity |
|
Curcumin |
4.84 | 19297423 |
MESH:D009765 |
Obesity |
|
pirinixic acid |
4.84 | 20558911 |
MESH:D010024 |
Osteoporosis |
|
Curcumin |
3.67 | 18719352 |
MESH:D010051 |
Ovarian Neoplasms |
|
Curcumin |
2.90 | 18462866 19020741 |
MESH:D010146 |
Pain |
|
Acetaminophen |
2.69 | 16870215 |
MESH:D010190 |
Pancreatic Neoplasms |
|
Curcumin |
3.03 | 17440100 19401701 19196508 |
MESH:D011471 |
Prostatic Neoplasms |
|
Curcumin |
3.87 | 11398177 18769126 10851300 18156803 12497104 18226269 15129424 |
MESH:D011471 |
Prostatic Neoplasms |
|
pyrrolidine dithiocarbamic acid |
3.87 | 16139439 |
MESH:D011656 |
Pulmonary Emphysema |
|
Curcumin |
4.88 | 19168576 |
MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.53 | 19058328 |
MESH:D012128 |
Respiratory Distress Syndrome, Adult |
|
Curcumin |
11.04 | 10666014 18379247 |
MESH:D012128 |
Respiratory Distress Syndrome, Adult |
|
pyrrolidine dithiocarbamic acid |
11.04 | 16129981 |
MESH:D012509 |
Sarcoma |
|
Curcumin |
4.46 | 18462866 |
MESH:D018805 |
Sepsis |
|
Curcumin |
4.38 | 18389075 |
MESH:D013276 |
Stomach Ulcer |
|
Curcumin |
3.86 | 19188055 16631530 |
MESH:D001749 |
Urinary Bladder Neoplasms |
|
Curcumin |
3.00 | 18593936 |
MESH:D014565 |
Urogenital Neoplasms |
|
Curcumin |
5.80 | 18462866 |
MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.38 | 10982225 |