AutismKB 2.0

Annotation Detail for MT1A


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Basic Information Top
Gene Symbol:MT1A ( MGC32848,MT1,MT1S,MTC )
Gene Full Name: metallothionein 1A
Band: 16q13
Quick LinksEntrez ID:4489; OMIM: 156350; Uniprot ID:MT1A_HUMAN; ENSEMBL ID: ENSG00000205362; HGNC ID: 7393
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1887Carcinoma
1904Diabetes mellitus
1855Prostatic hypertrophy, Benign
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C084012 1,1-diethyl-2-hydroxy-2-nitrosohydrazine 1,1-diethyl-2-hydroxy-2-nitrosohydrazine inhibits the reaction [Cadmium binds to MT1A protein]affects binding|decreases reaction 8924612
C477931 1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate 1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate promotes the reaction [Zinc results in increased expression of MT1A mRNA]increases expression|increases reaction 17363595
C477931 1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate 1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate results in increased expression of MT1A mRNAincreases expression 17363595
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of MT1A mRNAaffects expression 21346803
C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Zinc results in increased expression of MT1A mRNA]increases expression|increases reaction 17363595
C035208 2-amino-4,6-dinitrotoluene 2-amino-4,6-dinitrotoluene affects the expression of MT1A mRNAaffects expression 21346803
C019499 2-nitrofluorene 2-nitrofluorene results in decreased expression of MT1A mRNAdecreases expression 15890375
14600272
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of MT1A mRNAaffects expression 21346803
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MT1A mRNAdecreases expression 14600272
15890375
D000082 Acetaminophen Acetaminophen affects the expression of MT1A mRNAaffects expression 16701773
D000082 Acetaminophen Acetaminophen results in increased expression of MT1A mRNAincreases expression 15120968
17202762
D016604 Aflatoxin B1 Aflatoxin B1 results in decreased expression of MT1A mRNAdecreases expression 14600272
15890375
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MT1A mRNAaffects expression 16483693
D001115 Arecoline Arecoline results in increased expression of MT1A mRNAincreases expression 17418620
D001115 Arecoline Benzo(a)pyrene promotes the reaction [Arecoline results in increased expression of MT1A mRNA]increases expression|increases reaction 17418620
D001151 Arsenic Arsenic binds to MT1A proteinaffects binding 16984198
D001151 Arsenic Arsenic results in decreased expression of MT1A mRNAdecreases expression 17637929
D001151 Arsenic Arsenic results in increased expression of MT1A mRNAincreases expression 17409696
C006632 arsenic trioxide arsenic trioxide results in increased expression of MT1A mRNAincreases expression 19128835
D001414 Bacitracin Bacitracin results in increased expression of MT1A mRNAincreases expression 18289764
D001554 Benzene Benzene affects the expression of MT1A mRNAaffects expression 15878777
D001564 Benzo(a)pyrene Benzo(a)pyrene promotes the reaction [Arecoline results in increased expression of MT1A mRNA]increases expression|increases reaction 17418620
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of MT1A mRNAdecreases expression 20064835
C002791 bismuth tripotassium dicitrate bismuth tripotassium dicitrate results in increased expression of MT1A mRNAincreases expression 15912405
D019328 Buthionine Sulfoximine Buthionine Sulfoximine results in increased expression of MT1A mRNAincreases expression 7626009
D002104 Cadmium Cadmium results in increased expression of MT1A mRNAincreases expression 16827180
12716893
17409696
D002104 Cadmium Cadmium results in increased expression of MT1A proteinincreases expression 15664440
D002104 Cadmium chromium hexavalent ion inhibits the reaction [Cadmium results in increased expression of MT1A mRNA]decreases reaction|increases expression 12716893
D002104 Cadmium 1,1-diethyl-2-hydroxy-2-nitrosohydrazine inhibits the reaction [Cadmium binds to MT1A protein]affects binding|decreases reaction 8924612
D002104 Cadmium Cadmium binds to MT1A proteinaffects binding 8924612
D002104 Cadmium Cadmium results in decreased expression of MT1A mRNAdecreases expression 14694715
D002104 Cadmium Cadmium affects the expression of MT1A mRNAaffects expression 12140172
D002104 Cadmium Cadmium affects the expression of MT1A proteinaffects expression 12140172
D002104 Cadmium Cadmium results in increased expression of MT1A mRNAincreases expression 12854162
11430474
17327699
D002104 Cadmium Cadmium results in increased expression of MT1A proteinincreases expression 17443291
D002104 Cadmium MT1A protein results in decreased susceptibility to Cadmiumdecreases response to substance 17443291
16516943
D019256 Cadmium Chloride Cadmium Chloride results in increased expression of MT1A proteinincreases expression 15788722
D019256 Cadmium Chloride MT1A protein results in decreased susceptibility to Cadmium Chloridedecreases response to substance 11878821
D019256 Cadmium Chloride Cadmium Chloride affects the expression of MT1A mRNAaffects expression 15795064
D019256 Cadmium Chloride Cadmium Chloride results in increased expression of MT1A mRNAincreases expression 17327699
15454312
D019256 Cadmium Chloride Cadmium Chloride results in increased expression of MT1A proteinincreases expression 15249216
17443291
D019256 Cadmium Chloride MT1A protein affects the metabolism of Cadmium Chlorideaffects metabolic processing 15249216
D019256 Cadmium Chloride MT1A protein results in decreased susceptibility to Cadmium Chloridedecreases response to substance 17443291
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of MT1A mRNAdecreases expression 16239168
D002259 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MT1A mRNAdecreases expression 16039398
D002509 Cephaloridine Cephaloridine results in decreased expression of MT1A mRNAdecreases expression 18172885
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in increased expression of MT1A mRNAincreases expression 18178546
C074702 chromium hexavalent ion chromium hexavalent ion inhibits the reaction [Cadmium results in increased expression of MT1A mRNA]decreases reaction|increases expression 12716893
C074702 chromium hexavalent ion chromium hexavalent ion inhibits the reaction [MTF1 protein binds to MT1A promoter]affects binding|decreases reaction 12716893
C074702 chromium hexavalent ion chromium hexavalent ion inhibits the reaction [Zinc results in increased expression of MT1A mRNA]decreases reaction|increases expression 12716893
C018021 cobaltous chloride cobaltous chloride results in increased expression of MT1A mRNAincreases expression 7626009
D003300 Copper Copper affects the expression of MT1A mRNAaffects expression 12140172
D003300 Copper Copper affects the expression of MT1A proteinaffects expression 12140172
D003300 Copper Copper results in increased expression of MT1A mRNAincreases expression 15591161
D003345 Corticosterone Corticosterone results in increased expression of MT1A mRNAincreases expression 15755911
C030123 coumarin coumarin results in increased expression of MT1A mRNAincreases expression 18480146
D013759 Tetrahydrocannabinol Tetrahydrocannabinol results in increased expression of MT1A mRNAincreases expression 16039398
D003907 Dexamethasone Dexamethasone results in increased expression of MT1A mRNAincreases expression 15851833
D003907 Dexamethasone Dexamethasone results in increased expression of MT1A mRNAincreases expression 16962226
D016190 Carboplatin Carboplatin results in decreased expression of MT1A mRNAdecreases expression 18172885
D002945 Cisplatin Cisplatin results in increased expression of MT1A mRNAincreases expression 12680227
D002945 Cisplatin Cisplatin results in decreased expression of MT1A mRNAdecreases expression 18172885
D002945 Cisplatin Cisplatin results in increased expression of MT1A mRNAincreases expression 18289764
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of MT1A mRNAincreases expression 15890375
D004128 Dimethylnitrosamine Dimethylnitrosamine results in decreased expression of MT1A mRNAdecreases expression 17072980
14600272
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of MT1A mRNAincreases expression 15890375
D004391 Dust Dust results in increased expression of MT1A mRNAincreases expression 17805423
D004958 Estradiol Estradiol results in increased expression of MT1A mRNAincreases expression 19153601
D000431 Ethanol Ethanol results in increased expression of MT1A mRNAincreases expression 17637929
D000431 Ethanol Ethanol results in increased expression of MT1A proteinincreases expression 17637929
D000431 Ethanol [Fish Oils co-treated with Ethanol] results in decreased expression of MT1A mRNAaffects cotreatment|decreases expression 17347304
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of MT1A mRNAdecreases expression 17557909
15834898
C024555 ferric chloride MT1A protein results in decreased susceptibility to ferric chloridedecreases response to substance 11878821
C020748 ferrous sulfate ferrous sulfate results in increased expression of and affects the localization of MT1A proteinaffects localization|increases expression 17241390
C020748 ferrous sulfate [Zinc Sulfate co-treated with ferrous sulfate] results in increased expression of and affects the localization of MT1A proteinaffects cotreatment|affects localization|increases expression 17241390
D005395 Fish Oils [Fish Oils co-treated with Ethanol] results in decreased expression of MT1A mRNAaffects cotreatment|decreases expression 17347304
D015073 2-Acetylaminofluorene 2-Acetylaminofluorene results in increased expression of MT1A proteinincreases expression 15565650
D015073 2-Acetylaminofluorene Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of MT1A protein]decreases reaction|increases expression 15565650
C039281 furan furan results in decreased expression of MT1A mRNAdecreases expression 15120968
C040641 genistin genistin analog results in increased expression of MT1A mRNAincreases expression 16719502
D005978 Glutathione Glutathione deficiency results in increased expression of MT1A mRNAincreases expression 15345336
D006418 Heme MT1A protein results in decreased susceptibility to Hemedecreases response to substance 11878821
D006581 Hexachlorobenzene Hexachlorobenzene results in increased expression of MT1A mRNAincreases expression 15159207
C475919 hydroxytamoxifen GPR30 protein affects the reaction [hydroxytamoxifen results in increased expression of MT1A mRNA]affects reaction|increases expression 19153601
C475919 hydroxytamoxifen hydroxytamoxifen results in increased expression of MT1A mRNAincreases expression 19153601
D007501 Iron Iron results in increased expression of and affects the localization of MT1A proteinaffects localization|increases expression 17241390
D007501 Iron [Zinc co-treated with Iron] results in increased expression of and affects the localization of MT1A proteinaffects cotreatment|affects localization|increases expression 17241390
D019266 Iron, Dietary Iron, Dietary affects the expression of MT1A mRNAaffects expression 15637178
D007608 Kainic Acid Kainic Acid results in increased expression of MT1A mRNAincreases expression 12692462
D007654 Ketoconazole Ketoconazole results in increased expression of MT1A mRNAincreases expression 18289764
D001556 Lindane Lindane results in increased expression of MT1A mRNAincreases expression 17785943
D008315 Malondialdehyde Malondialdehyde results in increased expression of MT1A proteinincreases expression 15640275
C039798 manganese sulfate manganese sulfate results in decreased expression of MT1A mRNAdecreases expression 15894815
D008628 Mercury Mercury results in increased expression of MT1Aincreases expression 15138662
D008628 Mercury Mercury results in increased expression of MT1A proteinincreases expression 12491035
D008701 Methapyrilene Methapyrilene results in decreased expression of MT1A mRNAdecreases expression 15120968
D008701 Methapyrilene Methapyrilene results in increased expression of MT1A mRNAincreases expression 15890375
D008727 Methotrexate Methotrexate results in increased expression of MT1A mRNAincreases expression 15120968
C437683 motexafin gadolinium [Zinc co-treated with motexafin gadolinium] results in increased expression of MT1A mRNAaffects cotreatment|increases expression 15867382
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in increased expression of MT1A mRNAincreases expression 18289764
D009569 Nitric Oxide Nitric Oxide binds to and results in decreased activity of MT1A proteinaffects binding|decreases activity 10548558
D009599 Nitroprusside Nitroprusside results in increased expression of MT1A mRNAincreases expression 17018880
D009599 Nitroprusside N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nitroprusside results in increased expression of MT1A mRNA]decreases reaction|increases expression 17018880
D009599 Nitroprusside Zinc Sulfate promotes the reaction [Nitroprusside results in increased expression of MT1A mRNA]increases expression|increases reaction 17018880
C044387 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nitroprusside results in increased expression of MT1A mRNA]decreases reaction|increases expression 17018880
D009828 Oleanolic Acid Oleanolic Acid results in increased expression of MT1A mRNAincreases expression 17637929
D009828 Oleanolic Acid Oleanolic Acid results in increased expression of MT1A proteinincreases expression 17637929
D010100 Oxygen Oxygen results in increased expression of MT1A mRNAincreases expression 15680347
D010126 Ozone Ozone results in increased expression of MT1A mRNAincreases expression 16716893
D010269 Paraquat MT1A protein results in decreased susceptibility to Paraquatdecreases response to substance 15288509
D010269 Paraquat Paraquat results in increased expression of MT1A mRNAincreases expression 16555045
D010269 Paraquat Paraquat results in increased expression of MT1A proteinincreases expression 16555045
D010615 Phenacetin Phenacetin results in increased expression of MT1A mRNAincreases expression 17082564
C030299 phenylhydrazine phenylhydrazine results in increased expression of MT1A mRNAincreases expression 17082564
C018637 phorone phorone results in decreased expression of MT1A mRNAdecreases expression 7626009
D010882 Piperonyl Butoxide Piperonyl Butoxide results in increased expression of MT1A mRNAincreases expression 15890375
C006253 pirinixic acid pirinixic acid results in decreased expression of MT1A mRNAdecreases expression 15890375
D011374 Progesterone Progesterone results in increased expression of MT1A mRNAincreases expression 18037150
D011794 Quercetin Quercetin affects the expression of MT1A mRNAaffects expression 18178720
C009277 sodium arsenate sodium arsenate affects the expression of MT1A mRNAaffects expression 18848598
C017947 sodium arsenite sodium arsenite results in increased expression of MT1A mRNAincreases expression 11693492
20339138
12679051
C017947 sodium arsenite sodium arsenite results in increased expression of MT1A proteinincreases expression 11693492
C017947 sodium arsenite sodium arsenite results in increased expression of MT1A mRNAincreases expression 16876216
D018038 Sodium Selenite Sodium Selenite results in increased expression of MT1A mRNAincreases expression 18175754
D013311 Streptozocin Streptozocin results in increased expression of MT1A mRNAincreases expression 16684804
D013311 Streptozocin vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of MT1A mRNA]decreases reaction|increases expression 16684804
C016766 sulforafan sulforafan results in increased expression of MT1A mRNAincreases expression 16033772
C016766 sulforafan sulforafan results in increased expression of MT1A proteinincreases expression 16033772
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of MT1A mRNAdecreases expression 16039398
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of MT1A mRNAincreases expression 16054898
18178546
18465118
11521753
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of MT1A proteinincreases expression 11521753
D014639 Vanadium Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of MT1A protein]decreases reaction|increases expression 15565650
C034028 vanadyl sulfate vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of MT1A mRNA]decreases reaction|increases expression 16684804
D014640 Vancomycin Vancomycin results in increased expression of MT1A mRNAincreases expression 18289764
D015032 Zinc 1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate promotes the reaction [Zinc results in increased expression of MT1A mRNA]increases expression|increases reaction 17363595
D015032 Zinc 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Zinc results in increased expression of MT1A mRNA]increases expression|increases reaction 17363595
D015032 Zinc chromium hexavalent ion inhibits the reaction [Zinc results in increased expression of MT1A mRNA]decreases reaction|increases expression 12716893
D015032 Zinc Zinc binds to MT1A proteinaffects binding 10548558
D015032 Zinc [Zinc co-treated with motexafin gadolinium] results in increased expression of MT1A mRNAaffects cotreatment|increases expression 15867382
D015032 Zinc Zinc results in increased expression of MT1A mRNAincreases expression 17409696
15867382
11168427
12716893
17363595
D015032 Zinc Zinc results in increased expression of MT1A mRNAincreases expression 15612480
D015032 Zinc Zinc affects the expression of MT1A mRNAaffects expression 14690761
D015032 Zinc [Zinc co-treated with Iron] results in increased expression of and affects the localization of MT1A proteinaffects cotreatment|affects localization|increases expression 17241390
D015032 Zinc Zinc results in increased expression of and affects the localization of MT1A proteinaffects localization|increases expression 17241390
D015032 Zinc Zinc results in increased expression of MT1A mRNAincreases expression 17241390
15952664
18172885
17074742
C016837 zinc chloride MT1A protein results in decreased susceptibility to zinc chloridedecreases response to substance 15288509
C016837 zinc chloride zinc chloride results in increased expression of MT1A mRNAincreases expression 17637929
C016837 zinc chloride zinc chloride results in increased expression of MT1A proteinincreases expression 17637929
D019287 Zinc Sulfate Zinc Sulfate promotes the reaction [Nitroprusside results in increased expression of MT1A mRNA]increases expression|increases reaction 17018880
D019287 Zinc Sulfate Zinc Sulfate results in increased expression of MT1A mRNAincreases expression 17018880
D019287 Zinc Sulfate [Zinc Sulfate co-treated with ferrous sulfate] results in increased expression of and affects the localization of MT1A proteinaffects cotreatment|affects localization|increases expression 17241390
D019287 Zinc Sulfate Zinc Sulfate results in increased expression of and affects the localization of MT1A proteinaffects localization|increases expression 17241390
D019287 Zinc Sulfate Zinc Sulfate results in increased expression of MT1A mRNAincreases expression 17074742
17241390
15884113
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 2-amino-4,6-dinitrotoluene 18.327525203
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 18.327525203
MESH:D000014 Abnormalities, Drug-Induced Ethanol 18.3218926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Methotrexate 18.3212039119
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 18.3214514962 11752688 15322242
MESH:D000138 Acidosis Ammonium Chloride 13.2318287403
MESH:D000138 Acidosis Ethanol 13.2311192467
MESH:D000138 Acidosis Zinc Sulfate 13.237265320
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.1217505938
MESH:D000169 Acrodermatitis Zinc 4.6017190629 17202136 16889938
MESH:D058186 Acute Kidney Injury Cisplatin 3.2415814532 12690470 17670903
MESH:D055371 Acute Lung Injury Oxygen 6.7516759491
MESH:D055371 Acute Lung Injury pirinixic acid 6.7518653653
MESH:D000230 Adenocarcinoma arsenic trioxide 13.2419825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 13.2420127859 20464547
MESH:D000230 Adenocarcinoma Cisplatin 13.2411798837 17638652
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 13.2416033868
MESH:D000230 Adenocarcinoma Estradiol 13.2411473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 13.2414692618
MESH:D000236 Adenoma 2-Acetylaminofluorene 11.7110737359
MESH:D000236 Adenoma 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 11.7116176798
MESH:D000236 Adenoma Benzo(a)pyrene 11.716695378
MESH:D000236 Adenoma Dimethylnitrosamine 11.7119555203
MESH:D002759 Adenoma, Bile Duct 2-Acetylaminofluorene 5.196705139
MESH:D018248 Adenoma, Liver Cell pirinixic acid 7.2416434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 7.2416835633
MESH:D011125 Adenomatous Polyposis Coli sulforafan 4.5517942926
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.8815276417
MESH:D018246 Adrenocortical Adenoma Arsenic 11.0717306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 11.0716712894 17306315
MESH:D000382 Agricultural Workers' Diseases Lindane 6.3412661182
MESH:D000382 Agricultural Workers' Diseases Paraquat 6.3411874814
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.5015451040 15451039
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 4.8416640825
MESH:D000544 Alzheimer Disease Copper 9.6516886094 16325427 16962711 17119284 16410023 16866297
MESH:D000544 Alzheimer Disease Iron 9.6516640825 16563566
MESH:D000544 Alzheimer Disease Nitric Oxide 9.6517556102
MESH:D000544 Alzheimer Disease Ozone 9.6515513908
MESH:D000544 Alzheimer Disease Zinc 9.6516410023 16325427 16580781 17119284
MESH:D000686 Amyloidosis Diethylstilbestrol 3.7115469931
MESH:D000690 Amyotrophic Lateral Sclerosis Copper 6.9310694572
MESH:D000690 Amyotrophic Lateral Sclerosis Tetrahydrocannabinol 6.9315204022
MESH:D000740 Anemia Iron 20.3416434484 16566752
MESH:D000740 Anemia Malondialdehyde 20.3417278206
MESH:D000740 Anemia Phenacetin 20.342444515
MESH:D000740 Anemia phenylhydrazine 20.342444515
MESH:D000740 Anemia Tetrachlorodibenzodioxin 20.3411748828
MESH:D000741 Anemia, Aplastic Benzene 3.7211369114 14761424 17661222
MESH:D000743 Anemia, Hemolytic Phenacetin 13.1217698508 1949026 17082564
MESH:D000743 Anemia, Hemolytic phenylhydrazine 13.1217698508 17084956 17082564
MESH:D000743 Anemia, Hemolytic Quercetin 13.1217084956
MESH:D018798 Anemia, Iron-Deficiency Copper 8.1016614410
MESH:D018798 Anemia, Iron-Deficiency Iron 8.1016569441 17147795 17162259 17375513 17163184
MESH:D000755 Anemia, Sickle Cell Zinc 4.1316916123
MESH:D000756 Anemia, Sideroblastic Iron 4.0816910769
MESH:D000799 Angioedema Acetaminophen 3.0210982225
MESH:D000853 Anophthalmos Ethanol 4.0315513904
MESH:D000860 Anoxia Oxygen 8.8520872349
MESH:D000860 Anoxia Zinc Sulfate 8.857265320
MESH:D001008 Anxiety Disorders Ethanol 3.3411141031
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.2919183758
MESH:D001145 Arrhythmias, Cardiac Iron 3.6616604332
MESH:D020261 Arsenic Poisoning Arsenic 2.5712569548 16251483 18414634 16835338
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 2.6811256880
MESH:D001169 Arthritis, Experimental Dexamethasone 5.5217659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 5.5215885639
MESH:D001172 Arthritis, Rheumatoid Methotrexate 4.0617286800
MESH:D001172 Arthritis, Rheumatoid Ozone 4.0615570426
MESH:D001249 Asthma Ozone 4.0717854713 16373670
MESH:D001249 Asthma Zinc 4.0717085522
MESH:D001260 Ataxia Telangiectasia Iron 10.4415336622
MESH:D001260 Ataxia Telangiectasia Quercetin 10.4415336622
MESH:D050197 Atherosclerosis Arsenic 14.9019371607 12928151
MESH:D050197 Atherosclerosis Cadmium 14.9015687053
MESH:D050197 Atherosclerosis Iron 14.9016640825 16632123
MESH:D050197 Atherosclerosis Oxygen 14.9016391483
MESH:D050197 Atherosclerosis Tetrahydrocannabinol 14.9015815632
MESH:D001321 Autistic Disorder Acetaminophen 2.3418445737
MESH:D001321 Autistic Disorder Glutathione 2.3419056591 16917939 18929414 19267885
MESH:D001321 Autistic Disorder Iron 2.3417352947
MESH:D001321 Autistic Disorder Mercury 2.3417497416
MESH:D001327 Autoimmune Diseases Mercury 13.7716634805
MESH:D001327 Autoimmune Diseases Quercetin 13.7719761891
MESH:D001327 Autoimmune Diseases sulforafan 13.7719761891
MESH:D001424 Bacterial Infections Iron 4.3916640825
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 16.0716206674
MESH:D001778 Blood Coagulation Disorders ferrous sulfate 16.076421970
MESH:D001778 Blood Coagulation Disorders pirinixic acid 16.0719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 16.0712125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.9715340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.1915746008
MESH:D001855 Bone Marrow Diseases Benzene 4.4116183116
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.0714601052
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.5217868700
MESH:D001930 Brain Injuries Nitroprusside 14.0914637104
MESH:D001930 Brain Injuries Progesterone 14.0915665606 15845082 15380490
MESH:D001930 Brain Injuries Zinc 14.0917109824
MESH:D001932 Brain Neoplasms Copper 3.8517079463
MESH:D001943 Breast Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 13.1420146248
MESH:D001943 Breast Neoplasms Benzene 13.1417162533 11921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 13.1420146248 17474063
MESH:D001943 Breast Neoplasms Cisplatin 13.1419526202 18382427
MESH:D001943 Breast Neoplasms Copper 13.1415986119 17079463
MESH:D001943 Breast Neoplasms Diethylstilbestrol 13.1415324884 17129689
MESH:D001943 Breast Neoplasms Estradiol 13.1417261762 12948864 19861407 17289903 17018787 18497071 16675129 14630087
MESH:D001943 Breast Neoplasms Hexachlorobenzene 13.1412709520 15061365
MESH:D001943 Breast Neoplasms Lindane 13.1414688026
MESH:D001943 Breast Neoplasms Methotrexate 13.1416978400
MESH:D001943 Breast Neoplasms Nitric Oxide 13.1415631943
MESH:D001943 Breast Neoplasms Oxygen 13.1417263869
MESH:D001943 Breast Neoplasms Progesterone 13.1416175315 17614352 15562024
MESH:D001943 Breast Neoplasms Quercetin 13.1418628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 13.1420435547
MESH:D001943 Breast Neoplasms Vanadium 13.1415565634
MESH:D016535 Bronchial Hyperreactivity Ozone 3.0217626835 18417511 16777450 15516495 14754758 18315731 19059883
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.5811589617
MESH:D002056 Burns Ethanol 3.8716374292
MESH:D002100 Cachexia Ozone 3.9416183385
MESH:D002105 Cadmium Poisoning Quercetin 4.7216962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.6616111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 7.9210355542 18705752 15673190 16097048 3786805 16011737 15700767 16050911 16227642 16124888 15721981 16192424
MESH:D002252 Carbon Tetrachloride Poisoning Oleanolic Acid 7.9210355542
MESH:D002276 Carcinoid Tumor Streptozocin 4.7816051944
MESH:D002277 Carcinoma Dimethylnitrosamine 6.1619555203
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.1616835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.0717687452 15504454
MESH:D006528 Carcinoma, Hepatocellular marker/mechanism 19363144 17363595
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 29.6316705839
MESH:D006528 Carcinoma, Hepatocellular 2-Acetylaminofluorene 29.633581430 6705139 10737359 17761372 3084413
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 29.633084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 29.6321507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Arsenic 29.6317306315 16507464
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 29.6315553829 16217749 11135700 14691202 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 29.6318788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 29.6317982673
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 29.6315948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Estradiol 29.6316924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 29.6315289165 15763234 18788625
MESH:D006528 Carcinoma, Hepatocellular Quercetin 29.6312508355 19519916
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 29.6317306315 16507464 15276417
MESH:D006528 Carcinoma, Hepatocellular Vanadium 29.6316830150 16878318
MESH:D002289 Carcinoma, Non-Small-Cell Lung Carboplatin 4.9216685392
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 4.9212023789 16685392
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.1717234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.0519014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.4012490120
MESH:D002294 Carcinoma, Squamous Cell marker/mechanism 17418620
MESH:D002294 Carcinoma, Squamous Cell Arsenic 16.9417687452 18922899 15504454
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 16.9420419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 16.9417066447 18337622 6189445
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 16.9416033868
MESH:D002294 Carcinoma, Squamous Cell Glutathione 16.9417015178
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 16.9418572023
MESH:D002294 Carcinoma, Squamous Cell Zinc 16.9416543248
MESH:D002295 Carcinoma, Transitional Cell Arsenic 3.3718640142
MESH:D006332 Cardiomegaly Copper 12.1317327471
MESH:D006332 Cardiomegaly Ethanol 12.1319332462
MESH:D006332 Cardiomegaly Quercetin 12.1319794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 12.1318670907 18850075 16120746
MESH:D009202 Cardiomyopathies Iron 3.4716640825
MESH:D002311 Cardiomyopathy, Dilated Iron 5.1516604332
MESH:D002311 Cardiomyopathy, Dilated Mercury 5.1510334427
MESH:D002318 Cardiovascular Diseases Arsenic 5.6417938729 19152805 15738583
MESH:D002318 Cardiovascular Diseases Zinc 5.6416936243
MESH:D002340 Carotid Artery Diseases Arsenic 3.6116973168 18022660
MESH:D002375 Catalepsy Tetrahydrocannabinol 4.9210318961
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 5.6314694615
MESH:D002386 Cataract Acetaminophen 5.6310977129
MESH:D002471 Cell Transformation, Neoplastic Cadmium 14.8717332340
MESH:D002471 Cell Transformation, Neoplastic Estradiol 14.8718566989
MESH:D002471 Cell Transformation, Neoplastic manganese sulfate 14.878243401
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 14.8719524636 20056578
MESH:D002471 Cell Transformation, Neoplastic Vanadium 14.8717174075
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.4716835633
MESH:D002761 Cholangitis 1-Naphthylisothiocyanate 5.3812912871
MESH:D002779 Cholestasis 1-Naphthylisothiocyanate 14.1818164287 16629650 19486331 18590720 15500046 12927374 15913567 7624871
MESH:D002779 Cholestasis Ethinyl Estradiol 14.1816919318 17333356 11677210 17110522 16105132 15861022 17681005
MESH:D002779 Cholestasis Nitric Oxide 14.1816919318
MESH:D002779 Cholestasis pirinixic acid 14.1819176532
MESH:D002780 Cholestasis, Intrahepatic 1-Naphthylisothiocyanate 5.0310220858 19407337
MESH:D019457 Chromosome Breakage Sodium Selenite 3.9615894690
MESH:D002971 Cleft Lip Ethanol 3.1015513904
MESH:D002972 Cleft Palate Ethanol 4.5515513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 4.5515668235 15340226 16354765 8697196 12621046
MESH:D003110 Colonic Neoplasms Dexamethasone 6.4815824018
MESH:D003110 Colonic Neoplasms Iron 6.4816640825
MESH:D003110 Colonic Neoplasms Quercetin 6.4811134977 19056647 15741050 17191121 17148506 19440933 16640504
MESH:D003110 Colonic Neoplasms Vanadium 6.4818155637
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.8820501625
MESH:D015179 Colorectal Neoplasms Cisplatin 2.8815273666
MESH:D015179 Colorectal Neoplasms Quercetin 2.8818852136 18095365
MESH:D000013 Congenital Abnormalities 2-amino-4,6-dinitrotoluene 11.6915095906
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 11.6915095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 11.6914669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.4212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 11.5310525206
MESH:D019465 Craniofacial Abnormalities Benzene 11.5315643154
MESH:D019465 Craniofacial Abnormalities Dexamethasone 11.5317728286
MESH:D019465 Craniofacial Abnormalities Ethanol 11.5315513904 19302082 15451040 15451039 10194807 11873399 11198716
MESH:D019465 Craniofacial Abnormalities Methotrexate 11.539562676 12039119
MESH:D019465 Craniofacial Abnormalities sodium arsenate 11.5310525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 11.5310048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Zinc 11.5319302082
MESH:D003456 Cryptorchidism Diethylstilbestrol 3.7912952375 16002989
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.2318551238
MESH:D003550 Cystic Fibrosis Glutathione 6.8119747007
MESH:D003550 Cystic Fibrosis Methotrexate 6.8119747007
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.3515213294
MESH:D015140 Dementia, Vascular Nitric Oxide 5.1517556102
MESH:D003872 Dermatitis Benzene 3.9815902427
MESH:D017449 Dermatitis, Allergic Contact cobaltous chloride 7.4516823706 15059100 11298694
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 7.4512438553
MESH:D017449 Dermatitis, Allergic Contact Mercury 7.4516823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 1.9818249437
MESH:D003882 Dermatomyositis Methotrexate 4.3520191521
MESH:D003920 Diabetes Mellitus Iron 16.3416640825 16604332
MESH:D003920 Diabetes Mellitus Sodium Selenite 16.3416285004
MESH:D003920 Diabetes Mellitus Streptozocin 16.3416285004
MESH:D003920 Diabetes Mellitus Zinc 16.3416479319
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 10.2819496084
MESH:D003921 Diabetes Mellitus, Experimental Streptozocin 10.287637645 12446591 18715473 18603373 6379147 19496084 1374869 2177838 12093613 15862027 11055810 16684804 11260395 16286809 8740154 17874149 15831366 12644472 12083368 19586609 17442507 19298542 19960420 15298345
MESH:D003921 Diabetes Mellitus, Experimental vanadyl sulfate 10.2816684804
MESH:D003922 Diabetes Mellitus, Type 1 Iron 5.0016506275
MESH:D003922 Diabetes Mellitus, Type 1 Streptozocin 5.0018603373
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 7.9619647726
MESH:D003924 Diabetes Mellitus, Type 2 Iron 7.9616506275
MESH:D003924 Diabetes Mellitus, Type 2 Streptozocin 7.9619586609 19647726
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 7.9617107852
MESH:D058065 Diabetic Cardiomyopathies Streptozocin 4.9216025228
MESH:D003928 Diabetic Nephropathies Estradiol 6.9719279558
MESH:D003928 Diabetic Nephropathies Streptozocin 6.9719682444 19960420
MESH:D003929 Diabetic Neuropathies Progesterone 3.7017187935
MESH:D003930 Diabetic Retinopathy Streptozocin 4.6517662242
MESH:D003967 Diarrhea Dexamethasone 2.967237001
MESH:D056486 Drug-Induced Liver Injury 1-Naphthylisothiocyanate 31.9717522070 7624871 20133375 18289764
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 31.9721346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2-amino-4,6-dinitrotoluene 31.9721346803
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 31.9721346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 31.9718713872 10663392 11739529 12958197 11743745 12705907 12392966 10915739 19370779 11529661 2444490 16781746 15619225 14725611 19164858 17906064 12594235 17522070 19923254 15968718 14550746 11421492 16177239 19416960 16393943 18071297 10774834 11461765 12540782 19739265 16109766 11287661 16227642 14986274 19085960 11834606 16081117 17562736 19420014 12153990 16485898
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 31.9716177239 10092053 19085960 19336974 15968718 3786805 7440962 7179309 9327722 7120509 17522070 6884620 4309450 10915739 21278145 6623471 2869522 15998439 3732212 15027814 16227642 11566570
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 31.9717851650
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 31.978172417
MESH:D056486 Drug-Induced Liver Injury Ethanol 31.9711566570
MESH:D056486 Drug-Induced Liver Injury Ketoconazole 31.9718289764
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 31.9718186108
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 31.9715131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 31.9720420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.2819426721
MESH:D004362 Drug Toxicity Cisplatin 6.0812231392 12649298 15033597 19839026
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.0811462148
MESH:D004417 Dyspnea Oxygen 4.0220016425
MESH:D004485 Eczema Dexamethasone 3.6912438553
MESH:D004487 Edema Dexamethasone 7.3119703484
MESH:D004487 Edema pirinixic acid 7.3112083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 7.3111000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.0816714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 6.5012538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 6.5017692515
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 3.8916402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 5.6215700306 16804899
MESH:D016889 Endometrial Neoplasms Estradiol 5.6219148513 11473722 18566989
MESH:D004715 Endometriosis Progesterone 6.5716134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 6.579294722 10568697
MESH:D004827 Epilepsy Tetrahydrocannabinol 4.01821787
MESH:D004938 Esophageal Neoplasms arsenic trioxide 13.5412903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 13.5416530937
MESH:D004938 Esophageal Neoplasms Cisplatin 13.5416481741 15464296 17638652 16785472 15173087
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 13.5417016578
MESH:D004938 Esophageal Neoplasms Ethanol 13.5416704527
MESH:D004938 Esophageal Neoplasms Zinc 13.5416543248
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.3811564622
MESH:D005234 Fatty Liver arsenic trioxide 25.9415073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 25.9415959796 17595544 12795759 16045604 12631006 19224547 16239168 61145
MESH:D005234 Fatty Liver Ethanol 25.9418620774 16409862 19236843
MESH:D005234 Fatty Liver Ethinyl Estradiol 25.9415345470
MESH:D005234 Fatty Liver Fish Oils 25.9418620774
MESH:D005234 Fatty Liver Iron 25.9416640825
MESH:D005234 Fatty Liver pirinixic acid 25.9420131406 19236843
MESH:D005235 Fatty Liver, Alcoholic Ethanol 4.8417920746
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.1116002989 16513791 16534752 16611131 15751030
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.4915513904 16946407 10194807 15451040
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.6711858732
MESH:D005355 Fibrosis Carbon Tetrachloride 10.3118705752
MESH:D005355 Fibrosis Quercetin 10.3119474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 10.3120067830
MESH:D005534 Foot Diseases Arsenic 4.746392382
MESH:D005621 Friedreich Ataxia Iron 4.6416604332 16640825
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.4916904648
MESH:D005739 Gas Poisoning Oxygen 4.4020016425
MESH:D005756 Gastritis Acetaminophen 14.3516983495
MESH:D005756 Gastritis Ethanol 14.3515046732
MESH:D005756 Gastritis Zinc 14.3517241300
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 10.1416452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 10.1416452187
MESH:D005909 Glioblastoma Quercetin 2.8319804834
MESH:D005910 Glioma Quercetin 2.6717643826
MESH:D005911 Gliosis Paraquat 4.3411124998
MESH:D018149 Glucose Intolerance sodium arsenate 4.3319446573
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.7710696789
MESH:D006086 Graft vs Host Disease Methotrexate 4.3616518429
MESH:D006130 Growth Disorders Zinc 3.3917217573
MESH:D006261 Headache Nitric Oxide 4.3611284996 11554966
MESH:D006258 Head and Neck Neoplasms Cisplatin 3.1315102660 15464296
MESH:D034381 Hearing Loss Cisplatin 3.6019898482
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 3.7315464296
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 4.7920471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 4.7910048152 11294989
MESH:D006331 Heart Diseases Streptozocin 3.6812093613
MESH:D006333 Heart Failure pirinixic acid 5.3020558911
MESH:D006333 Heart Failure Zinc 5.3017162251
MESH:D006335 Heart Injuries Zinc 4.9517074742
MESH:D016481 Helicobacter Infections Malondialdehyde 8.7017278206
MESH:D016481 Helicobacter Infections Zinc 8.7017241300
MESH:D006390 Hemangioendothelioma 2-Acetylaminofluorene 4.506705139
MESH:D006394 Hemangiosarcoma 2-Acetylaminofluorene 3.686705139
MESH:D006402 Hematologic Diseases Benzene 3.9016183116
MESH:D006432 Hemochromatosis Iron 3.8616604332 17236123 17255318 16574947 17053826 16640825
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.6011000095
MESH:D006486 Hemosiderosis Iron 4.4016604332
MESH:D006505 Hepatitis 1-Naphthylisothiocyanate 7.1218590720
MESH:D006505 Hepatitis Carbon Tetrachloride 7.1219900420 19110552
MESH:D006521 Hepatitis, Chronic Copper 4.4617338147
MESH:D006525 Hepatitis, Viral, Human Iron 4.6516640825
MESH:D006527 Hepatolenticular Degeneration Copper 20.0019888908 17109627 16607473 17276780 17182432
MESH:D006527 Hepatolenticular Degeneration Iron 20.0017182432
MESH:D006527 Hepatolenticular Degeneration Zinc 20.0017276780
MESH:D006527 Hepatolenticular Degeneration Zinc Sulfate 20.0017063115
MESH:D006529 Hepatomegaly Iron 9.9916890145
MESH:D006529 Hepatomegaly pirinixic acid 9.9919176532 16221962 18467677 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 9.9912621046 15340226 16120746
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.727520565
MESH:D006558 Herpes Genitalis Estradiol 4.2115709030
MESH:D015658 HIV Infections Iron 3.1916597321
MESH:D006689 Hodgkin Disease Cisplatin 5.2916200630 16170182
MESH:D006689 Hodgkin Disease sodium arsenite 5.2912676792
MESH:D019584 Hot Flashes Estradiol 2.9417088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.2316354765 15340226 16959395 8697196 18606429
MESH:D006930 Hyperalgesia Acetaminophen 5.6316870215
MESH:D006930 Hyperalgesia Ethanol 5.6318783367
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.7316899240
MESH:D006940 Hyperemia Nitric Oxide 4.8111156591
MESH:D006943 Hyperglycemia pirinixic acid 6.8820558911
MESH:D006943 Hyperglycemia Quercetin 6.8811834736 18262572
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 3.7417050553
MESH:D006949 Hyperlipidemias Fish Oils 7.7015752949
MESH:D006949 Hyperlipidemias Oleanolic Acid 7.708847885
MESH:D006965 Hyperplasia Diethylstilbestrol 3.6512960047 14722030
MESH:D006968 Hypersensitivity, Delayed Fish Oils 4.6911484837
MESH:D006973 Hypertension Arsenic 12.2016076760 11953799 9931084
MESH:D006973 Hypertension Benzene 12.2017940673
MESH:D006973 Hypertension Dexamethasone 12.2017042910
MESH:D006973 Hypertension Quercetin 12.2018356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 12.2018850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.3015338365
MESH:D006976 Hypertension, Pulmonary Nitric Oxide 3.8115838368
MESH:D006987 Hypesthesia Arsenic 4.7416093927
MESH:D007006 Hypogonadism Iron 3.7916640825
MESH:D007021 Hypospadias Diethylstilbestrol 8.6316002989
MESH:D007021 Hypospadias Ethinyl Estradiol 8.6316945680 16569931
MESH:D007022 Hypotension Zinc Sulfate 3.737265320
MESH:D007035 Hypothermia Tetrahydrocannabinol 5.1410318961
MESH:D007037 Hypothyroidism Iron 4.2916640825
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.6115869954
MESH:D007246 Infertility Diethylstilbestrol 3.5915036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.7112013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 7.8517937319
MESH:D007248 Infertility, Male Paraquat 7.854850670
MESH:D007248 Infertility, Male sodium arsenite 7.8515346721 12646999
MESH:D007249 Inflammation Dexamethasone 10.7311099482 8960868
MESH:D007249 Inflammation Heme 10.7312649161
MESH:D007249 Inflammation Oleanolic Acid 10.738847885
MESH:D007249 Inflammation Progesterone 10.7315869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 10.7312878042 12200463
MESH:D007251 Influenza, Human Quercetin 3.6916624496
MESH:D007333 Insulin Resistance Estradiol 8.9616393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 8.9616306350
MESH:D007333 Insulin Resistance Sodium Selenite 8.9614714311
MESH:D007410 Intestinal Diseases Nitric Oxide 4.1511574821 11713966 10210152
MESH:D019189 Iron Metabolism Disorders Iron 4.2817163184
MESH:D007511 Ischemia Zinc 3.8516584753
MESH:D007569 Jaw Abnormalities Ethanol 7.6915513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 7.6916580747
MESH:D007627 Keloid Quercetin 4.1717086741
MESH:D007642 Keratosis Arsenic 4.1816930632 12749816
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.3215464296
MESH:D007674 Kidney Diseases Acetaminophen 41.6212587719 15629191
MESH:D007674 Kidney Diseases Bacitracin 41.6218289764
MESH:D007674 Kidney Diseases Cadmium 41.6216962696 16226777 16322080
MESH:D007674 Kidney Diseases Cadmium Chloride 41.6216962696
MESH:D007674 Kidney Diseases Cisplatin 41.6212649298 19839026 18289764 12231392 15190930
MESH:D007674 Kidney Diseases Estradiol 41.6215618244
MESH:D007674 Kidney Diseases Mercury 41.6217934191
MESH:D007674 Kidney Diseases Quercetin 41.6216962696
MESH:D007674 Kidney Diseases sodium arsenite 41.6220008137
MESH:D007674 Kidney Diseases Streptozocin 41.6212093613
MESH:D007674 Kidney Diseases Vancomycin 41.6218289764
MESH:D007674 Kidney Diseases Zinc 41.6216960431
MESH:D007676 Kidney Failure, Chronic Copper 12.9116518626
MESH:D007676 Kidney Failure, Chronic Malondialdehyde 12.9116518626
MESH:D007676 Kidney Failure, Chronic Zinc 12.9116518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 8.5816705839
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 8.5816762066 14681315 15003126
MESH:D007680 Kidney Neoplasms Estradiol 8.5815610895
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 3.9811231351
MESH:D007805 Language Development Disorders Methotrexate 4.359562676
MESH:D007859 Learning Disorders Copper 11.7217134702
MESH:D007859 Learning Disorders Diethylstilbestrol 11.7217184923
MESH:D007859 Learning Disorders Ethanol 11.7215451040
MESH:D007896 Leishmaniasis Nitric Oxide 3.9717218153
MESH:D016773 Leishmaniasis, Cutaneous Ketoconazole 6.851311351 2166429 19744259 8889330
MESH:D016773 Leishmaniasis, Cutaneous Zinc Sulfate 6.8515237267
MESH:D007898 Leishmaniasis, Visceral Ketoconazole 3.9111332679
MESH:D007938 Leukemia 1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate 14.6812970779
MESH:D007938 Leukemia 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 14.6812970779
MESH:D007938 Leukemia arsenic trioxide 14.6815070760
MESH:D007938 Leukemia Benzene 14.6818335105 15935818 14694614 17119257
MESH:D007938 Leukemia Quercetin 14.6817468513
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.0717077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.5016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 2.8014633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 7.2819077051
MESH:D007951 Leukemia, Myeloid Benzene 7.2817506065
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.3816467208 17050201 19850784 20471514 16968895
MESH:D015470 Leukemia, Myeloid, Acute Benzene 3.3819478238
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 5.8517339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 5.8517649720 12679006 17712046 19035177 17107899 15622746 16823087 16331271 15213294 15336539 16891316 19225113 11468182 9834237 16112521 16966277 19075265 15748426 12712474 17217047 11161223 12018890 19642359 17869043 16330433
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.5816882451
MESH:D020961 Lewy Body Disease Iron 4.6416563566
MESH:D017880 Limb Deformities, Congenital Ethanol 3.2017676605
MESH:D008064 Lipidoses Ketoconazole 3.9617567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 11.6316221502 16943688 21278145 11408273 11903743 16239168 17174718 17157831 17334410
MESH:D008103 Liver Cirrhosis Ethanol 11.6315289165
MESH:D008103 Liver Cirrhosis Iron 11.6316640825
MESH:D008103 Liver Cirrhosis Methotrexate 11.6314986274
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.2918295389
MESH:D008106 Liver Cirrhosis, Experimental marker/mechanism 17072980
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 12.3111481614 12958196 16015684 17761835 18054572 10355542 15338365 17721639 14620537 18205269 12546737 18279442 18705752 15893842 17698563 16116963 18481824 16192424 15673190 18317297 17714472 15052691 14716496 15362042 18376398 15996030 12632514 12586293 15370692 17900296 17944888 16011737 18166357 13678700 12445418 18187930 14748882 16097048 15057751 17976157 17823541 15123356 12898905 17640975 18395914 12445421 17869086 15959796 18472332 15876570 17481882 16033810 18420326 18418968 18277467 15818738 12389079 18263696 17922224 12632512 15931870 18339082 12666154 17525996 18472094 12667390 17557913 18429990 18395095 15650968 15730626 18156304 12609069 17631135 20821823 12741479 16638106 17565644 18251166 16027843 18412020 17766677 17805973 17708605 14724832 14716833 18006644 18210741 16248980 16136751 15925388 14512876 12649538
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 12.3116718785
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 12.3115369754 15099470 16169303 18371158 15504291 15492853 14568256 15942678 14709902 15339415 16627068 15138612 15571005 15733078 15383259 16603200 15864749 17465448 18239293 17432682 18629640 17203207 17534399 17640959 14726149 15067225 14643895 18364076 15577212 15086199 15161499 15479170 15798949 17196135 15744066 12925901 18637143 17348192 16009107 18095165 17198567 17036385 18567088 15842777 17724770 15081153 17201889 18237412 15793283 16570917 12918455 14659978 15723089 17719030 16270385 17666798 18672772 15366600 17881167 15763062 16042886 16544323 15591649 18210741 15298665
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 12.3114659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 12.3118166357
MESH:D008106 Liver Cirrhosis, Experimental Oleanolic Acid 12.3110355542
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 12.3115474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 12.3112741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 12.3112878042
MESH:D008107 Liver Diseases 1-Naphthylisothiocyanate 11.9417184895
MESH:D008107 Liver Diseases Acetaminophen 11.9416611625 19460945 11587558 19784758 12587719 19014921 16610002 12969438
MESH:D008107 Liver Diseases Arsenic 11.9411134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 11.9416246199 15720792 17285989 15830285 16964402
MESH:D008107 Liver Diseases Lindane 11.941715830
MESH:D008107 Liver Diseases Oleanolic Acid 11.948847885 15720792
MESH:D008108 Liver Diseases, Alcoholic Ethanol 8.8817347304 17207112
MESH:D008108 Liver Diseases, Alcoholic Iron 8.8817207112 16737972
MESH:D017093 Liver Failure Carbon Tetrachloride 3.3815123358
MESH:D017114 Liver Failure, Acute Acetaminophen 12.1517185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 12.1514706259 16899240
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 12.1517457977
MESH:D008113 Liver Neoplasms 2-Acetylaminofluorene 56.3016273603 14678523 18001218 10737359 10672840 11376686
MESH:D008113 Liver Neoplasms 2-nitrofluorene 56.3015890375
MESH:D008113 Liver Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 56.3015890375
MESH:D008113 Liver Neoplasms Aflatoxin B1 56.3018177683 9163691 15890375 2125692
MESH:D008113 Liver Neoplasms Arsenic 56.3016368122
MESH:D008113 Liver Neoplasms arsenic trioxide 56.3014682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 56.3020195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 56.3019294768
MESH:D008113 Liver Neoplasms Copper 56.3020302851
MESH:D008113 Liver Neoplasms Diethylstilbestrol 56.3016712894 15890375
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 56.303113478 15890375
MESH:D008113 Liver Neoplasms Iron 56.3020302851 16640825
MESH:D008113 Liver Neoplasms Methapyrilene 56.3015890375
MESH:D008113 Liver Neoplasms Piperonyl Butoxide 56.3018648771 20101389 15890375 19690152
MESH:D008113 Liver Neoplasms pirinixic acid 56.3015890375 16377806 20007298
MESH:D008113 Liver Neoplasms Quercetin 56.3018980244
MESH:D008113 Liver Neoplasms sodium arsenite 56.3015276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 56.3016984957
MESH:D008114 Liver Neoplasms, Experimental 2-Acetylaminofluorene 31.396150874 1399818 534488
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 31.398603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 31.3920377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 31.3912562636
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 31.3912014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 31.391848544 6150874 15603536
MESH:D008114 Liver Neoplasms, Experimental Hexachlorobenzene 31.391423854
MESH:D008114 Liver Neoplasms, Experimental Quercetin 31.3919519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 31.3912151625
MESH:D008114 Liver Neoplasms, Experimental Vanadium 31.3917174075
MESH:D008133 Long QT Syndrome arsenic trioxide 2.7115213294
MESH:D008171 Lung Diseases chromium hexavalent ion 9.1516775837
MESH:D008171 Lung Diseases Ozone 9.1519066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 9.1519095001
MESH:D017563 Lung Diseases, Interstitial Benzene 8.9514698565
MESH:D017563 Lung Diseases, Interstitial Methotrexate 8.9518516814
MESH:D055370 Lung Injury Nitric Oxide 10.9011395602
MESH:D055370 Lung Injury Oxygen 10.9018339021
MESH:D055370 Lung Injury Ozone 10.9020417186
MESH:D008175 Lung Neoplasms 2-Acetylaminofluorene 28.8711376686
MESH:D008175 Lung Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 28.8715893417 9255578 18508827 14755239 15172992 17139156 19931552 16061637 12438228 16401635 18813816
MESH:D008175 Lung Neoplasms Aflatoxin B1 28.8714755239
MESH:D008175 Lung Neoplasms Arsenic 28.8717306315 17976673 19168569
MESH:D008175 Lung Neoplasms arsenic trioxide 28.8719825857 11798837
MESH:D008175 Lung Neoplasms Benzene 28.8712562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 28.8720064080 18569708 20869020 18816296 18520028 20135361 20464547 6695378 17053015
MESH:D008175 Lung Neoplasms chromium hexavalent ion 28.8716876463 16570259
MESH:D008175 Lung Neoplasms Cisplatin 28.876189445 17225452 11798837
MESH:D008175 Lung Neoplasms Dexamethasone 28.8711195469 15824018
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 28.8716061637 19555203 11884234
MESH:D008175 Lung Neoplasms Iron 28.8716640825
MESH:D008175 Lung Neoplasms Ozone 28.877614698 8597069
MESH:D008175 Lung Neoplasms Quercetin 28.8716280456
MESH:D008175 Lung Neoplasms sodium arsenite 28.8717306315 17077188 15276417 19931552 16712894
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 28.8719555203 11884234
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.3415166399
MESH:D008207 Lymphatic Metastasis marker/mechanism 17418620
MESH:D008223 Lymphoma Benzene 12.9517119257 17584886
MESH:D008223 Lymphoma Diethylstilbestrol 12.9515700306
MESH:D008223 Lymphoma Methotrexate 12.9517352296
MESH:D008223 Lymphoma Nitric Oxide 12.9516166326
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 3.3114737004
MESH:D008268 Macular Degeneration Iron 3.4716640825
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.6916002989
MESH:D015674 Mammary Neoplasms, Animal Benzene 3.6512562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 12.8411921183
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 12.8412807724
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 12.8416891317 11807958 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 12.8417203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Zinc 12.8412773700
MESH:D020149 Manganese Poisoning Estradiol 3.6619453300
MESH:D008545 Melanoma Carboplatin 4.1316225601 16342250 12040289 11712820
MESH:D008545 Melanoma Cisplatin 4.1312883367 16432458 18332650 17023156 18176117 15577323 12374674 16809738 11135225 16248763 12393984 18505091 17761969
MESH:D008545 Melanoma sodium arsenite 4.1316487513 19082730
MESH:D018328 Melanoma, Amelanotic Cisplatin 3.9715990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.7819513568
MESH:D008569 Memory Disorders Ethanol 3.4318411066 15451040
MESH:D007706 Menkes Kinky Hair Syndrome Copper 5.0717109627 17268249
MESH:D008654 Mesothelioma Cisplatin 2.8517638057
MESH:D008679 Metaplasia Ozone 4.2810496685
MESH:D008708 Methemoglobinemia Phenacetin 4.211949026 3537620 4834387 16296465
MESH:D008881 Migraine Disorders Nitric Oxide 3.6811701602
MESH:D020326 Migraine without Aura Nitric Oxide 4.3511304026 14659530
MESH:D009062 Mouth Neoplasms marker/mechanism 17418620
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.5516381670
MESH:D052016 Mucositis Methotrexate 4.4817488658
MESH:D009101 Multiple Myeloma arsenic trioxide 8.6815949261 19417148 11468182 14977855 19549372
MESH:D009101 Multiple Myeloma Benzene 8.6817119195
MESH:D009101 Multiple Myeloma Dexamethasone 8.6815867202 16118317 15744524
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 4.8517086897
MESH:D009135 Muscular Diseases pirinixic acid 2.7216239165
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 4.1218186108
MESH:D009181 Mycoses Iron 4.6516640825
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.8518349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 5.8016882451 16105982
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 5.809809623
MESH:D009203 Myocardial Infarction pirinixic acid 4.3419151258
MESH:D009203 Myocardial Infarction Quercetin 4.3419595682
MESH:D017202 Myocardial Ischemia Arsenic 11.5215371236
MESH:D017202 Myocardial Ischemia Iron 11.5216604332
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 11.5212213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 15.0316810080
MESH:D015428 Myocardial Reperfusion Injury Iron 15.0316604332
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 15.0316411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 15.0319207477
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.0618551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.1916624393
MESH:D009369 Neoplasms Benzo(a)pyrene 23.4611141357
MESH:D009369 Neoplasms Carboplatin 23.4618854779 17925555
MESH:D009369 Neoplasms Cisplatin 23.4616773208
MESH:D009369 Neoplasms Diethylstilbestrol 23.4615313581
MESH:D009369 Neoplasms Lindane 23.4616818664 12807735
MESH:D009369 Neoplasms Oleanolic Acid 23.468847885
MESH:D009369 Neoplasms pirinixic acid 23.4617405874
MESH:D009369 Neoplasms Quercetin 23.4615185748
MESH:D009369 Neoplasms sodium arsenite 23.4611559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 2.8920056578
MESH:D009389 Neovascularization, Pathologic Copper 7.6917308104
MESH:D009389 Neovascularization, Pathologic Estradiol 7.6917289903
MESH:D009395 Nephritis, Interstitial Cisplatin 3.6815464296
MESH:D009404 Nephrotic Syndrome Iron 3.8217178036
MESH:D009410 Nerve Degeneration Paraquat 3.0716893418
MESH:D009421 Nervous System Malformations Diethylstilbestrol 11.9611399458
MESH:D009421 Nervous System Malformations Estradiol 11.9611399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 11.9614600291
MESH:D009436 Neural Tube Defects Arsenic 20.9616620997
MESH:D009436 Neural Tube Defects arsenic trioxide 20.9610525206
MESH:D009436 Neural Tube Defects Benzene 20.9615643154
MESH:D009436 Neural Tube Defects sodium arsenate 20.9619446573 18186108 10525206 11749123
MESH:D009436 Neural Tube Defects sodium arsenite 20.9612854658
MESH:D009436 Neural Tube Defects Tetrahydrocannabinol 20.9619040278
MESH:D009447 Neuroblastoma Cisplatin 2.978761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 6.2718514411
MESH:D019636 Neurodegenerative Diseases Iron 6.2716604332 17296847
MESH:D017599 Neuroectodermal Tumors Carboplatin 9.1312837982
MESH:D017599 Neuroectodermal Tumors Cisplatin 9.138761367
MESH:D020078 Neurogenic Inflammation Arsenic 8.2017056641
MESH:D020078 Neurogenic Inflammation Quercetin 8.2017929310
MESH:D009669 Nose Neoplasms chromium hexavalent ion 4.3316876463
MESH:D009765 Obesity pirinixic acid 1.5620558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 11.1512819281 16049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 11.1514694615
MESH:D009784 Occupational Diseases Benzene 11.1517178637 15935809 17479406 16737584 17119257 15727169 15576619 15612468 15913788
MESH:D009914 Oral Submucous Fibrosis Arecoline 5.3716311067
MESH:D010003 Osteoarthritis Iron 3.4316640825
MESH:D010024 Osteoporosis Iron 3.3216640825 16648989
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 3.4719495926
MESH:D010051 Ovarian Neoplasms 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 24.5716211241
MESH:D010051 Ovarian Neoplasms Arsenic 24.5717306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 24.5712452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Benzene 24.5712562636
MESH:D010051 Ovarian Neoplasms Cisplatin 24.5717225452 6897625 15464296 19769630
MESH:D010051 Ovarian Neoplasms Estradiol 24.5719401270
MESH:D010051 Ovarian Neoplasms Progesterone 24.5716525653 17393432
MESH:D010051 Ovarian Neoplasms Quercetin 24.5719005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 24.5715276417 17306315
MESH:D010146 Pain Acetaminophen 1.7616870215
MESH:D010190 Pancreatic Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 12.3012384795
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 12.3015580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 12.3019003803
MESH:D010190 Pancreatic Neoplasms Ethanol 12.3012384795
MESH:D010190 Pancreatic Neoplasms Quercetin 12.3016965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.9411578682
MESH:D010212 Papilloma Iron 3.7112065085
MESH:D010235 Paraganglioma arsenic trioxide 3.4119927285
MESH:D020447 Parasomnias Iron 5.2017352947
MESH:D010300 Parkinson Disease Iron 4.4316563566 16640825
MESH:D010300 Parkinson Disease Paraquat 4.4311445065 15451049 12911755 15824117 11124998 11181820 16510128 16140633
MESH:D010302 Parkinson Disease, Secondary Paraquat 3.6516190885
MESH:D010382 Peliosis Hepatis 1-Naphthylisothiocyanate 11.0720133375
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 11.0712520081
MESH:D010523 Peripheral Nervous System Diseases Arsenic 7.5216093927
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 7.5215464296
MESH:D016491 Peripheral Vascular Diseases Arsenic 10.4216905509 6392382 15371236
MESH:D016491 Peripheral Vascular Diseases Cadmium 10.4215687053
MESH:D010538 Peritonitis Ozone 3.3516369182
MESH:D010900 Pituitary Diseases Diethylstilbestrol 11.3414722030
MESH:D010900 Pituitary Diseases Iron 11.3416604332
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 3.8816977796 15687265
MESH:D010997 Pleural Neoplasms Cisplatin 4.5217638057
MESH:D011014 Pneumonia Ozone 8.4018929643 18381685 18007984
MESH:D011014 Pneumonia Paraquat 8.4012504350
MESH:D011015 Pneumonia, Aspiration Nitric Oxide 4.5318573544
MESH:D011041 Poisoning Iron 3.5616604332
MESH:D017119 Porphyria Cutanea Tarda Hexachlorobenzene 14.369918132
MESH:D017119 Porphyria Cutanea Tarda Iron 14.3616640825
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 14.3618163543
MESH:D011230 Precancerous Conditions Quercetin 3.2919056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.0321297632
MESH:D011225 Pre-Eclampsia Iron 7.3816640825
MESH:D011225 Pre-Eclampsia Zinc 7.3817114810
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 6.9117184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 6.9111118676 11222880 11399792 11896295
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.1520887781
MESH:D011471 Prostatic Neoplasms Arsenic 4.8216140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 4.8219131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 4.8217292933
MESH:D011471 Prostatic Neoplasms Cadmium 4.8217075824
MESH:D011471 Prostatic Neoplasms Copper 4.8217308104 17079463
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 4.8217136230 15846301 15046698
MESH:D011471 Prostatic Neoplasms Estradiol 4.8216740699
MESH:D011471 Prostatic Neoplasms Ketoconazole 4.8217404083
MESH:D011471 Prostatic Neoplasms Lindane 4.8214688026 12661182
MESH:D011471 Prostatic Neoplasms Quercetin 4.8217292933 14715546
MESH:D011471 Prostatic Neoplasms sodium arsenite 4.8216039940
MESH:D011471 Prostatic Neoplasms Sodium Selenite 4.8218760546
MESH:D011471 Prostatic Neoplasms Zinc 4.8212429649 16700911 16517595 16606632
MESH:D011507 Proteinuria Arsenic 3.2621343184
MESH:D011528 Protozoan Infections Iron 5.2016640825
MESH:D011537 Pruritus Ethinyl Estradiol 2.5216919318 15861022
MESH:D011565 Psoriasis Methotrexate 3.0817410198
MESH:D011658 Pulmonary Fibrosis Paraquat 2.5417997886 16324872
MESH:D051437 Renal Insufficiency Cisplatin 7.9615464296
MESH:D051437 Renal Insufficiency Methotrexate 7.9617352296
MESH:D015427 Reperfusion Injury pirinixic acid 1.9319058328
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 11.0211700416 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 11.0217627322 18339021
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 11.0211700416
MESH:D012135 Respiratory Sounds Paraquat 3.2811874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.0718990726
MESH:D012148 Restless Legs Syndrome Iron 3.9116930377
MESH:D012162 Retinal Degeneration Paraquat 7.0716458197
MESH:D012162 Retinal Degeneration Zinc 7.0716584753
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.5018045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 7.8016646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 7.8014601052
MESH:D012554 Schistosomiasis japonica Quercetin 4.7216862918
MESH:D012555 Schistosomiasis mansoni Nitric Oxide 4.689673227
MESH:D012559 Schizophrenia Copper 2.9516842975
MESH:D012640 Seizures 2,4-dinitrotoluene 12.4418551238
MESH:D012640 Seizures Ethanol 12.449754883
MESH:D012640 Seizures ferric chloride 12.4412941455
MESH:D012640 Seizures Kainic Acid 12.4410686065 18657176 17827730 1641125 16336964 15686955 19414003 14637104 19186208
MESH:D012640 Seizures Lindane 12.4412842176 15475178 7539098
MESH:D012871 Skin Diseases Arsenic 2.4815952646 16353154 18709164 16759981 17453740 16702368 6392382 17050553 17548696 19834688 17938729
MESH:D012878 Skin Neoplasms Arsenic 13.0515504454 17029826 17976673 16251483 19538983 17050553
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 13.0510029692 19755658
MESH:D012878 Skin Neoplasms Iron 13.0512065085
MESH:D012878 Skin Neoplasms sodium arsenite 13.0518572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 13.0516192470
MESH:D012893 Sleep Disorders Kainic Acid 4.9019414003
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.5215464296
MESH:D013088 Spermatocele Diethylstilbestrol 9.0016002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 9.0016709447
MESH:D013119 Spinal Cord Injuries Progesterone 3.4815862959 16503802
MESH:D016135 Spinal Dysraphism sodium arsenite 3.1412854658
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.4512587719
MESH:D013272 Stomach Diseases Dexamethasone 3.5215472012
MESH:D013274 Stomach Neoplasms arsenic trioxide 6.5017007042
MESH:D013274 Stomach Neoplasms Benzene 6.5012562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 6.502093021 20155912
MESH:D013274 Stomach Neoplasms Cisplatin 6.5015958060 17522103 18396642
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 6.5016033868
MESH:D013274 Stomach Neoplasms Ethanol 6.5018456281
MESH:D013276 Stomach Ulcer Dexamethasone 8.1415138204
MESH:D013276 Stomach Ulcer Ethanol 8.1411906479 17189318 17918041 9562338 16755016 9211565
MESH:D013276 Stomach Ulcer Nitric Oxide 8.1415138204
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.549754883
MESH:D013398 Sudden Infant Death Iron 10.6416640825
MESH:D013398 Sudden Infant Death Oxygen 10.6412563064
MESH:D013436 Sulfhemoglobinemia Phenacetin 5.73978859
MESH:D015173 Supratentorial Neoplasms Carboplatin 5.0112837982
MESH:D013576 Syndactyly Methotrexate 4.269562676
MESH:D013610 Tachycardia Nitroprusside 4.8515306635
MESH:D013736 Testicular Neoplasms Cisplatin 3.8815464296 17225452
MESH:D013921 Thrombocytopenia 1-Naphthylisothiocyanate 4.0420133375
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.8711994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.4615669648
MESH:D013953 Thymus Neoplasms Benzene 4.1510850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.0812697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 2.4719014326
MESH:D013978 Tibial Fractures Estradiol 3.8619048282
MESH:D014062 Tongue Neoplasms Zinc 3.6916543248
MESH:D016171 Torsades de Pointes arsenic trioxide 3.1615213294
MESH:D014376 Tuberculosis Iron 3.5316597321
MESH:D001749 Urinary Bladder Neoplasms marker/mechanism 16565513
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 28.7216049721
MESH:D001749 Urinary Bladder Neoplasms 2-Acetylaminofluorene 28.721399818 15867355 15289314
MESH:D001749 Urinary Bladder Neoplasms Arsenic 28.7219322015 18640142 15987713 19429237 11144890 17976673 17306315
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 28.7212973940 20435036 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 28.7217053015
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 28.7215464296 12973940 17225452
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 28.7216712894 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Phenacetin 28.7211144890
MESH:D001749 Urinary Bladder Neoplasms Quercetin 28.7216720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 28.7216452187 16712894 17306315 11723127
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.5110091137
MESH:D014581 Urticaria Acetaminophen 2.2410982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 11.8416803524
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 11.8416175088
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 11.8411813266
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.3514652134
MESH:D014594 Uterine Neoplasms Benzene 11.6812562636
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 11.6815809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 11.6814692618
MESH:D014605 Uveitis Dexamethasone 4.001336536
MESH:D014625 Vaginal Neoplasms Cisplatin 8.4715577323
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 8.4716002989 16513791
MESH:D014652 Vascular Diseases Arsenic 9.1817056641
MESH:D014652 Vascular Diseases sodium arsenite 9.1817056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.7712125929
MESH:D014689 Venous Insufficiency coumarin 4.9612708602
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.8114671159 15869587
MESH:D014839 Vomiting Cisplatin 3.9011897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.4315886252
MESH:D014947 Wounds and Injuries Heme 4.6212649161
Pathway ID Pathway Name
KEGG:04978 Mineral absorption
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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