Annotation Detail for ASTN1
Basic Information Top
| Gene Symbol: | ASTN1 ( ASTN,KIAA1747 ) |
|---|---|
| Gene Full Name: | astrotactin 1 |
| Band: | 1q25.2 |
| Quick Links | Entrez ID:460; OMIM: 600904; Uniprot ID:ASTN1_HUMAN; ENSEMBL ID: ENSG00000152092; HGNC ID: 773 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D002945 | Cisplatin | ASTN1 protein affects the susceptibility to Cisplatin | affects response to substance | 16217747 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D058186 | Acute Kidney Injury | Cisplatin | 4.58 | 15814532 17670903 12690470 | |
| MESH:D000230 | Adenocarcinoma | Cisplatin | 2.85 | 17638652 11798837 | |
| MESH:D019046 | Bone Marrow Neoplasms | Cisplatin | 6.30 | 14601052 | |
| MESH:D001943 | Breast Neoplasms | Cisplatin | 2.75 | 18382427 19526202 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Cisplatin | 2.46 | 17982673 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | Cisplatin | 3.17 | 12023789 16685392 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Cisplatin | 2.93 | 6189445 18337622 17066447 | |
| MESH:D015179 | Colorectal Neoplasms | Cisplatin | 2.33 | 15273666 | |
| MESH:D004362 | Drug Toxicity | Cisplatin | 4.26 | 12231392 12649298 19839026 15033597 | |
| MESH:D004938 | Esophageal Neoplasms | Cisplatin | 2.87 | 16785472 15464296 16481741 17638652 15173087 | |
| MESH:D006258 | Head and Neck Neoplasms | Cisplatin | 4.06 | 15102660 15464296 | |
| MESH:D034381 | Hearing Loss | Cisplatin | 4.82 | 19898482 | |
| MESH:D006319 | Hearing Loss, Sensorineural | Cisplatin | 4.91 | 15464296 | |
| MESH:D006689 | Hodgkin Disease | Cisplatin | 4.11 | 16170182 16200630 | |
| MESH:D007673 | Kidney Cortex Necrosis | Cisplatin | 6.56 | 15464296 | |
| MESH:D007674 | Kidney Diseases | Cisplatin | 3.51 | 18289764 12231392 15190930 12649298 19839026 | |
| MESH:D007683 | Kidney Tubular Necrosis, Acute | Cisplatin | 6.21 | 11231351 | |
| MESH:D008175 | Lung Neoplasms | Cisplatin | 2.34 | 11798837 17225452 6189445 | |
| MESH:D008545 | Melanoma | Cisplatin | 2.52 | 17023156 12393984 15577323 18505091 16432458 18332650 16809738 12374674 17761969 18176117 16248763 11135225 12883367 | |
| MESH:D018328 | Melanoma, Amelanotic | Cisplatin | 5.86 | 15990972 | |
| MESH:D008654 | Mesothelioma | Cisplatin | 3.41 | 17638057 | |
| MESH:D009369 | Neoplasms | Cisplatin | 3.15 | 16773208 | |
| MESH:D009395 | Nephritis, Interstitial | Cisplatin | 5.91 | 15464296 | |
| MESH:D009447 | Neuroblastoma | Cisplatin | 3.68 | 8761367 | |
| MESH:D017599 | Neuroectodermal Tumors | Cisplatin | 5.79 | 8761367 | |
| MESH:D010051 | Ovarian Neoplasms | Cisplatin | 2.99 | 6897625 15464296 19769630 17225452 | |
| MESH:D010190 | Pancreatic Neoplasms | Cisplatin | 3.13 | 19003803 | |
| MESH:D010523 | Peripheral Nervous System Diseases | Cisplatin | 5.09 | 15464296 | |
| MESH:D010997 | Pleural Neoplasms | Cisplatin | 6.76 | 17638057 | |
| MESH:D051437 | Renal Insufficiency | Cisplatin | 5.31 | 15464296 | |
| MESH:D012512 | Sarcoma, Ewing's | Cisplatin | 5.21 | 14601052 | |
| MESH:D055752 | Small Cell Lung Carcinoma | Cisplatin | 6.76 | 15464296 | |
| MESH:D013274 | Stomach Neoplasms | Cisplatin | 2.33 | 15958060 17522103 18396642 | |
| MESH:D013736 | Testicular Neoplasms | Cisplatin | 5.33 | 15464296 17225452 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Cisplatin | 3.10 | 15464296 12973940 17225452 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Cisplatin | 4.78 | 16803524 | |
| MESH:D014625 | Vaginal Neoplasms | Cisplatin | 5.52 | 15577323 | |
| MESH:D014839 | Vomiting | Cisplatin | 6.13 | 11897121 |
| No data |