Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
---|
C010914 |
2,4-diaminotoluene |
2,4-diaminotoluene results in increased expression of MYO1C mRNA | increases expression | 20713471
|
C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of MYO1C mRNA | affects expression | 21346803
|
D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of MYO1C mRNA | affects expression | 16483693
|
D002251 |
Carbon Tetrachloride |
Carbon Tetrachloride results in increased expression of MYO1C mRNA | increases expression | 16644059
|
D004997 |
Ethinyl Estradiol |
Ethinyl Estradiol affects the expression of MYO1C mRNA | affects expression | 17555576
|
D004997 |
Ethinyl Estradiol |
Ethinyl Estradiol results in increased expression of MYO1C mRNA | increases expression | 17942748
|
D004997 |
Ethinyl Estradiol |
[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MYO1C mRNA | affects cotreatment|increases expression | 17942748
|
C056933 |
fumonisin B1 |
fumonisin B1 results in increased expression of MYO1C mRNA | increases expression | 16221962
|
C006253 |
pirinixic acid |
pirinixic acid results in decreased expression of MYO1C mRNA | decreases expression | 17426115
|
C006253 |
pirinixic acid |
pirinixic acid results in increased expression of MYO1C mRNA | increases expression | 18301758
|
D013629 |
Tamoxifen |
Tamoxifen affects the expression of MYO1C mRNA | affects expression | 17555576
|
D013749 |
Tetrachlorodibenzodioxin |
[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MYO1C mRNA | affects cotreatment|increases expression | 17942748
|
C025643 |
vinclozolin |
vinclozolin affects the expression of MYO1C mRNA | affects expression | 19015723
|
Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
---|
MESH:D000008 |
Abdominal Neoplasms |
|
Tamoxifen |
4.81 | 14745880 |
MESH:D000014 |
Abnormalities, Drug-Induced |
|
Tetrachlorodibenzodioxin |
3.08 | 11752688 15322242 14514962 |
MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
3.80 | 18287403 |
MESH:D000152 |
Acne Vulgaris |
|
Ethinyl Estradiol |
4.21 | 17505938 |
MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.30 | 18653653 |
MESH:D000230 |
Adenocarcinoma |
|
Ethinyl Estradiol |
1.85 | 14692618 |
MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
10.71 | 16434500 |
MESH:D018248 |
Adenoma, Liver Cell |
|
Tetrachlorodibenzodioxin |
10.71 | 16835633 |
MESH:D000740 |
Anemia |
|
Tetrachlorodibenzodioxin |
3.11 | 11748828 |
MESH:D001008 |
Anxiety Disorders |
|
vinclozolin |
3.78 | 19015723 |
MESH:D001161 |
Arteriosclerosis |
|
Ethinyl Estradiol |
3.68 | 11256880 |
MESH:D001169 |
Arthritis, Experimental |
|
Ethinyl Estradiol |
2.76 | 15885639 |
MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
9.35 | 19483382 |
MESH:D001778 |
Blood Coagulation Disorders |
|
Tetrachlorodibenzodioxin |
9.35 | 12125929 |
MESH:D001836 |
Body Weight Changes |
|
Tetrachlorodibenzodioxin |
4.06 | 15340226 |
MESH:D001848 |
Bone Diseases, Developmental |
|
Tetrachlorodibenzodioxin |
2.87 | 15746008 |
MESH:D001943 |
Breast Neoplasms |
|
2,4-diaminotoluene |
1.95 | 11921183 |
MESH:D001943 |
Breast Neoplasms |
|
Tamoxifen |
1.95 | 18815881 19487384 19084267 20390343 19155303 17049068 18629630 19410462 18855134 19244106 16202921 17242785 19142967 21152245 15565566 16273361 19011961 17261762 15668708 18425577 20544844 19059307 19221464 18984771 17893378 16818667 19189210 11161223 20859285 19289846 19288272 19200415 19189212 20065188 19115204 18821012 20135344 16873071 19066611 21138602 17440819 18997820 18351453 19103187 20005174 |
MESH:D001943 |
Breast Neoplasms |
|
Tetrachlorodibenzodioxin |
1.95 | 20435547 |
MESH:D002252 |
Carbon Tetrachloride Poisoning |
|
Carbon Tetrachloride |
3.99 | 16192424 16227642 16124888 15700767 18705752 15673190 16050911 15721981 3786805 16097048 16011737 10355542 |
MESH:D002277 |
Carcinoma |
|
Tetrachlorodibenzodioxin |
2.93 | 16835633 |
MESH:D018270 |
Carcinoma, Ductal, Breast |
|
Tamoxifen |
4.72 | 19066611 |
MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
4.71 | 16705839 |
MESH:D006528 |
Carcinoma, Hepatocellular |
|
Carbon Tetrachloride |
4.71 | 18788625 |
MESH:D006528 |
Carcinoma, Hepatocellular |
|
Tamoxifen |
4.71 | 16924424 |
MESH:D002295 |
Carcinoma, Transitional Cell |
|
Tamoxifen |
3.78 | 17572228 |
MESH:D006332 |
Cardiomegaly |
|
Tetrachlorodibenzodioxin |
2.45 | 18850075 16120746 18670907 |
MESH:D018281 |
Cholangiocarcinoma |
|
Tetrachlorodibenzodioxin |
3.31 | 16835633 |
MESH:D002779 |
Cholestasis |
|
Ethinyl Estradiol |
8.17 | 17681005 17333356 16105132 17110522 16919318 11677210 15861022 |
MESH:D002779 |
Cholestasis |
|
pirinixic acid |
8.17 | 19176532 |
MESH:D002972 |
Cleft Palate |
|
Tetrachlorodibenzodioxin |
2.16 | 12621046 8697196 15668235 15340226 16354765 |
MESH:D000013 |
Congenital Abnormalities |
|
Tetrachlorodibenzodioxin |
3.21 | 14669216 17141729 |
MESH:D019465 |
Craniofacial Abnormalities |
|
Tetrachlorodibenzodioxin |
1.26 | 15322242 20055451 10048152 |
MESH:D003456 |
Cryptorchidism |
|
vinclozolin |
4.54 | 14966744 |
MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
4.23 | 18551238 |
MESH:D003711 |
Demyelinating Diseases |
|
Tamoxifen |
4.58 | 19031437 |
MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.49 | 18249437 |
MESH:D003924 |
Diabetes Mellitus, Type 2 |
|
Tetrachlorodibenzodioxin |
1.70 | 17107852 |
MESH:D003928 |
Diabetic Nephropathies |
|
Tamoxifen |
3.63 | 19279558 |
MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
9.39 | 21346803 18551238 |
MESH:D056486 |
Drug-Induced Liver Injury |
|
Carbon Tetrachloride |
9.39 | 11566570 4309450 7179309 7440962 10092053 10915739 6884620 6623471 7120509 15998439 3732212 21278145 15027814 17522070 19336974 9327722 2869522 16227642 16177239 3786805 19085960 15968718 |
MESH:D056486 |
Drug-Induced Liver Injury |
|
fumonisin B1 |
9.39 | 16221962 |
MESH:D056486 |
Drug-Induced Liver Injury |
|
Tetrachlorodibenzodioxin |
9.39 | 20420201 |
MESH:D004362 |
Drug Toxicity |
|
Tetrachlorodibenzodioxin |
2.89 | 11462148 |
MESH:D004487 |
Edema |
|
pirinixic acid |
7.11 | 12083418 |
MESH:D004487 |
Edema |
|
Tetrachlorodibenzodioxin |
7.11 | 11000095 12711302 |
MESH:D004489 |
Edema, Cardiac |
|
Tetrachlorodibenzodioxin |
4.17 | 18230668 15322242 16714409 |
MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Ethinyl Estradiol |
9.62 | 12538720 |
MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Tamoxifen |
9.62 | 19031437 |
MESH:D016889 |
Endometrial Neoplasms |
|
Tamoxifen |
3.15 | 20544844 16202921 19155303 17893378 |
MESH:D004715 |
Endometriosis |
|
Tetrachlorodibenzodioxin |
3.18 | 10568697 9294722 |
MESH:D005124 |
Eye Abnormalities |
|
Tetrachlorodibenzodioxin |
3.14 | 11564622 |
MESH:D005234 |
Fatty Liver |
|
Carbon Tetrachloride |
20.23 | 12631006 16239168 12795759 61145 17595544 16045604 15959796 19224547 |
MESH:D005234 |
Fatty Liver |
|
Ethinyl Estradiol |
20.23 | 15345470 |
MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
20.23 | 20131406 19236843 |
MESH:D005234 |
Fatty Liver |
|
Tamoxifen |
20.23 | 19224547 14986274 |
MESH:D052776 |
Female Urogenital Diseases |
|
Tamoxifen |
3.33 | 16709447 |
MESH:D005313 |
Fetal Death |
|
Tetrachlorodibenzodioxin |
3.67 | 11858732 |
MESH:D018221 |
Fibromatosis, Abdominal |
|
Tamoxifen |
4.76 | 14745880 |
MESH:D018222 |
Fibromatosis, Aggressive |
|
Tamoxifen |
4.42 | 19069698 |
MESH:D005355 |
Fibrosis |
|
Carbon Tetrachloride |
9.33 | 18705752 |
MESH:D005355 |
Fibrosis |
|
Tetrachlorodibenzodioxin |
9.33 | 20067830 |
MESH:D030342 |
Genetic Diseases, Inborn |
|
vinclozolin |
5.17 | 16973722 |
MESH:D005832 |
Genital Diseases, Male |
|
vinclozolin |
5.57 | 16417039 |
MESH:D006058 |
Gonadal Disorders |
|
Tetrachlorodibenzodioxin |
4.86 | 10696789 |
MESH:D006330 |
Heart Defects, Congenital |
|
Tetrachlorodibenzodioxin |
2.41 | 11294989 10048152 |
MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.63 | 20558911 |
MESH:D006470 |
Hemorrhage |
|
Tetrachlorodibenzodioxin |
3.51 | 11000095 |
MESH:D006505 |
Hepatitis |
|
Carbon Tetrachloride |
3.79 | 19900420 19110552 |
MESH:D006529 |
Hepatomegaly |
|
fumonisin B1 |
15.79 | 16221962 |
MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
15.79 | 16221962 18467677 19772884 19176532 |
MESH:D006529 |
Hepatomegaly |
|
Tetrachlorodibenzodioxin |
15.79 | 15340226 12621046 16120746 |
MESH:D006869 |
Hydronephrosis |
|
Tetrachlorodibenzodioxin |
4.31 | 8697196 15340226 16354765 16959395 18606429 |
MESH:D006932 |
Hyperbilirubinemia |
|
Carbon Tetrachloride |
4.77 | 16899240 |
MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.34 | 20558911 |
MESH:D006973 |
Hypertension |
|
Tetrachlorodibenzodioxin |
1.96 | 18670907 18850075 |
MESH:D006975 |
Hypertension, Portal |
|
Carbon Tetrachloride |
4.30 | 15338365 |
MESH:D007021 |
Hypospadias |
|
Ethinyl Estradiol |
4.02 | 16569931 16945680 |
MESH:D007247 |
Infertility, Female |
|
Ethinyl Estradiol |
3.65 | 12013081 |
MESH:D007248 |
Infertility, Male |
|
Ethinyl Estradiol |
7.03 | 17937319 |
MESH:D007248 |
Infertility, Male |
|
vinclozolin |
7.03 | 16467254 |
MESH:D007249 |
Inflammation |
|
Tamoxifen |
5.16 | 19457130 |
MESH:D007249 |
Inflammation |
|
Tetrachlorodibenzodioxin |
5.16 | 12200463 12878042 |
MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.74 | 16306350 |
MESH:D007569 |
Jaw Abnormalities |
|
Tetrachlorodibenzodioxin |
3.51 | 16580747 |
MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
7.87 | 16705839 |
MESH:D007680 |
Kidney Neoplasms |
|
Tamoxifen |
7.87 | 18625569 |
MESH:D007984 |
Leydig Cell Tumor |
|
vinclozolin |
4.97 | 16417039 |
MESH:D008064 |
Lipidoses |
|
Tamoxifen |
3.27 | 17567588 15342952 |
MESH:D008103 |
Liver Cirrhosis |
|
Carbon Tetrachloride |
2.89 | 16221502 11903743 11408273 17174718 16943688 21278145 17157831 16239168 17334410 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Carbon Tetrachloride |
5.06 | 16097048 15370692 17900296 18472332 16033810 12546737 16192424 12649538 12586293 17805973 12632512 17698563 17976157 14724832 18339082 15673190 18376398 17481882 12609069 14512876 18395095 11481614 18418968 12666154 12667390 14620537 17565644 16015684 17525996 14716496 17640975 15057751 12741479 20821823 12445421 12632514 18420326 17944888 18187930 12898905 15876570 17869086 18251166 12389079 16027843 18166357 15996030 17761835 15893842 17922224 18429990 14748882 15362042 15931870 15052691 17823541 15123356 15925388 15959796 12445418 15650968 18472094 14716833 18481824 18263696 16638106 17766677 18277467 12958196 15338365 16116963 18705752 17721639 18412020 17714472 17708605 10355542 18395914 18156304 18210741 18279442 18054572 13678700 15818738 18317297 18006644 18205269 17557913 16011737 16248980 17631135 16136751 15730626 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
5.06 | 15474484 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Tamoxifen |
5.06 | 18564211 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Tetrachlorodibenzodioxin |
5.06 | 12878042 |
MESH:D008107 |
Liver Diseases |
|
Carbon Tetrachloride |
2.12 | 16964402 17285989 15720792 15830285 16246199 |
MESH:D017093 |
Liver Failure |
|
Carbon Tetrachloride |
4.38 | 15123358 |
MESH:D017114 |
Liver Failure, Acute |
|
Carbon Tetrachloride |
3.85 | 14706259 16899240 |
MESH:D008113 |
Liver Neoplasms |
|
Carbon Tetrachloride |
11.16 | 19294768 |
MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
11.16 | 15890375 16377806 20007298 |
MESH:D008113 |
Liver Neoplasms |
|
Tamoxifen |
11.16 | 16684651 |
MESH:D008113 |
Liver Neoplasms |
|
Tetrachlorodibenzodioxin |
11.16 | 16984957 |
MESH:D008114 |
Liver Neoplasms, Experimental |
|
Carbon Tetrachloride |
6.10 | 15583823 12014681 |
MESH:D008114 |
Liver Neoplasms, Experimental |
|
Tetrachlorodibenzodioxin |
6.10 | 12151625 |
MESH:D008175 |
Lung Neoplasms |
|
Tamoxifen |
2.29 | 18625569 |
MESH:D008175 |
Lung Neoplasms |
|
Tetrachlorodibenzodioxin |
2.29 | 11884234 19555203 |
MESH:D015674 |
Mammary Neoplasms, Animal |
|
Tamoxifen |
4.00 | 19428831 |
MESH:D008325 |
Mammary Neoplasms, Experimental |
|
2,4-diaminotoluene |
6.70 | 11921183 |
MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Tamoxifen |
6.70 | 14580682 19196722 11731420 16827153 19196723 |
MESH:D020149 |
Manganese Poisoning |
|
Tamoxifen |
4.81 | 19453300 |
MESH:D008545 |
Melanoma |
|
Tamoxifen |
1.90 | 12393984 19393235 |
MESH:D018328 |
Melanoma, Amelanotic |
|
Tamoxifen |
4.42 | 15990972 |
MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
3.72 | 16239165 |
MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.20 | 19151258 |
MESH:D017202 |
Myocardial Ischemia |
|
Tetrachlorodibenzodioxin |
3.16 | 12213967 |
MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.08 | 16411023 |
MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
4.09 | 18551238 |
MESH:D009362 |
Neoplasm Metastasis |
|
Tamoxifen |
2.60 | 19393235 |
MESH:D009364 |
Neoplasm Recurrence, Local |
|
Tamoxifen |
2.56 | 19410462 |
MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.02 | 17405874 |
MESH:D009376 |
Neoplasms, Hormone-Dependent |
|
Tamoxifen |
4.26 | 19189210 19196722 19200415 |
MESH:D009421 |
Nervous System Malformations |
|
Tetrachlorodibenzodioxin |
3.41 | 14600291 |
MESH:D009765 |
Obesity |
|
pirinixic acid |
1.85 | 20558911 |
MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
3.59 | 16049721 12819281 |
MESH:D016584 |
Panic Disorder |
|
Ethinyl Estradiol |
3.87 | 11578682 |
MESH:D010382 |
Peliosis Hepatis |
|
Tetrachlorodibenzodioxin |
4.51 | 12520081 |
MESH:D017119 |
Porphyria Cutanea Tarda |
|
Tetrachlorodibenzodioxin |
3.76 | 18163543 |
MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
Tetrachlorodibenzodioxin |
10.29 | 11118676 11896295 11222880 11399792 |
MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
vinclozolin |
10.29 | 19015723 18220299 18042343 |
MESH:D011469 |
Prostatic Diseases |
|
vinclozolin |
5.17 | 18220299 |
MESH:D011471 |
Prostatic Neoplasms |
|
Tamoxifen |
3.12 | 15067354 |
MESH:D011472 |
Prostatitis |
|
vinclozolin |
5.17 | 18629315 |
MESH:D011537 |
Pruritus |
|
Ethinyl Estradiol |
3.55 | 16919318 15861022 |
MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.46 | 19058328 |
MESH:D015619 |
Respiratory System Abnormalities |
|
Tetrachlorodibenzodioxin |
4.04 | 18990726 |
MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
2.64 | 18551238 |
MESH:D012878 |
Skin Neoplasms |
|
Tetrachlorodibenzodioxin |
2.11 | 16192470 |
MESH:D013088 |
Spermatocele |
|
Ethinyl Estradiol |
12.46 | 16709447 |
MESH:D013088 |
Spermatocele |
|
Tamoxifen |
12.46 | 16709447 |
MESH:D013119 |
Spinal Cord Injuries |
|
Tamoxifen |
4.28 | 19457130 |
MESH:D019851 |
Thrombophilia |
|
Ethinyl Estradiol |
3.80 | 11994571 |
MESH:D013927 |
Thrombosis |
|
Ethinyl Estradiol |
3.30 | 15669648 |
MESH:D013959 |
Thyroid Diseases |
|
Tetrachlorodibenzodioxin |
4.17 | 12697716 |
MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
5.23 | 16049721 |
MESH:D001749 |
Urinary Bladder Neoplasms |
|
Tamoxifen |
5.23 | 8653321 17572228 16712894 |
MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
4.55 | 10091137 |
MESH:D014594 |
Uterine Neoplasms |
|
Ethinyl Estradiol |
3.50 | 14692618 |
MESH:D054079 |
Vascular Malformations |
|
Tetrachlorodibenzodioxin |
4.86 | 12125929 |
MESH:D020246 |
Venous Thrombosis |
|
Ethinyl Estradiol |
3.71 | 15869587 14671159 |
MESH:D019282 |
Wasting Syndrome |
|
Tetrachlorodibenzodioxin |
4.51 | 15886252 |