AutismKB 2.0

Annotation Detail for MYO5A


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MYO5A ( GS1,MYH12,MYO5,MYR12 )
Gene Full Name: myosin VA (heavy chain 12, myoxin)
Band: 15q21.2
Quick LinksEntrez ID:4644; OMIM: 160777; Uniprot ID:MYO5A_HUMAN; ENSEMBL ID: ENSG00000197535; HGNC ID: 7602
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Diabetes pathways
No data
Pathway IDPathway Name
P00044Nicotinic acetylcholine receptor signaling pathway
No data
Related Diseases/Disorders Top
Desease IDDesease Name
Immune system diseases
Primary immunodeficiency
H00101Other phagocyte defects
Desease IDDesease Name
2123Vitiligo
No data
No data
Desease Name
Griscelli syndrome, type 1
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of MYO5A mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MYO5A mRNAaffects expression 16483693
D000643 Ammonium Chloride Ammonium Chloride results in increased expression of MYO5A proteinincreases expression 16483693
D001194 Asbestos Asbestos affects the expression of MYO5A mRNAaffects expression 17297452
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of MYO5A mRNAincreases expression 15336504
D002699 Chlorambucil Chlorambucil results in increased mutagenesis of MYO5A geneincreases mutagenesis 10517996
D004041 Dietary Fats Dietary Fats results in decreased expression of MYO5A mRNAdecreases expression 18042831
D005038 Ethylnitrosourea Ethylnitrosourea results in increased mutagenesis of MYO5A geneincreases mutagenesis 17174358
10517996
9475716
9825669
D005419 Flavonoids Flavonoids results in decreased expression of MYO5A mRNAdecreases expression 18035473
D008770 Methylnitrosourea Methylnitrosourea results in increased mutagenesis of MYO5A geneincreases mutagenesis 17174358
10517996
D017239 Paclitaxel MYO5A protein results in increased susceptibility to Paclitaxelincreases response to substance 16734730
C041786 palm oil palm oil results in decreased expression of MYO5A mRNAdecreases expression 18042831
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of MYO5A mRNAaffects binding|increases activity|increases expression 19710929
D011794 Quercetin Quercetin results in increased expression of MYO5A proteinincreases expression 15221776
D013629 Tamoxifen Tamoxifen results in increased expression of MYO5A proteinincreases expression 17098229
D013629 Tamoxifen [Tretinoin co-treated with Tamoxifen] results in increased expression of MYO5A proteinaffects cotreatment|increases expression 17098229
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of MYO5A mRNAincreases expression 19465110
D014212 Tretinoin [Tretinoin co-treated with Tamoxifen] results in increased expression of MYO5A proteinaffects cotreatment|increases expression 17098229
D014212 Tretinoin Tretinoin results in increased expression of MYO5A proteinincreases expression 17098229
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.5814745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.8715322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.5818287403
MESH:D055371 Acute Lung Injury pirinixic acid 3.1218653653
MESH:D000230 Adenocarcinoma Methylnitrosourea 3.1215113128 15688392
MESH:D000236 Adenoma Ethylnitrosourea 3.726695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.9716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.9716835633
MESH:D000505 Alopecia Tretinoin 3.6215955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9511748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.2417084956
MESH:D000799 Angioedema Acetaminophen 3.8710982225
MESH:D001161 Arteriosclerosis Dietary Fats 3.9015238619
MESH:D001169 Arthritis, Experimental Tretinoin 3.0816412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2616292516
MESH:D001249 Asthma Tretinoin 2.3416456186
MESH:D001260 Ataxia Telangiectasia Quercetin 5.0015336622
MESH:D050197 Atherosclerosis Asbestos 4.2218795166
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001327 Autoimmune Diseases Quercetin 4.4219761891
MESH:D001471 Barrett Esophagus Tretinoin 4.4116935849
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.3019483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.3012125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 15.3016206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7615746008
MESH:D001859 Bone Neoplasms Paclitaxel 4.5715867366
MESH:D001927 Brain Diseases Ethylnitrosourea 4.8814991843
MESH:D001932 Brain Neoplasms Ethylnitrosourea 4.2916651633 16436596 16357521 18412241 15144691
MESH:D001943 Breast Neoplasms Dietary Fats 3.7820435547
MESH:D001943 Breast Neoplasms Methylnitrosourea 3.7814633655 11306469 16253758
MESH:D001943 Breast Neoplasms Paclitaxel 3.7816273361 11325840 16244791 16115903 18323546 18223236 15136595 18234424
MESH:D001943 Breast Neoplasms Quercetin 3.7818628248
MESH:D001943 Breast Neoplasms Tamoxifen 3.7819142967 19200415 19011961 19059307 18815881 19487384 18855134 19410462 17893378 17440819 18629630 21138602 16818667 17242785 18351453 16873071 19155303 19288272 19115204 20390343 15565566 15668708 19066611 18425577 20135344 21152245 20065188 20005174 18821012 19103187 19189210 17049068 20544844 17261762 19244106 20859285 16202921 18984771 19189212 16273361 19221464 19084267 18997820 19289846 11161223
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.7820435547
MESH:D001943 Breast Neoplasms Tretinoin 3.7816166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.6116813970
MESH:D002105 Cadmium Poisoning Quercetin 5.5816962696
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8016835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5219066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.1916168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.893084413
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 8.8916313753
MESH:D006528 Carcinoma, Hepatocellular Quercetin 8.8912508355 19519916
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 8.8916924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 8.891917145
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.9717234771
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.2916096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.6217572228
MESH:D006332 Cardiomegaly Quercetin 6.8119794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.8118670907 18850075 16120746
MESH:D002386 Cataract Acetaminophen 12.4310977129
MESH:D002386 Cataract Methylnitrosourea 12.4312484553
MESH:D002386 Cataract Tretinoin 12.4317460283
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 7.4016003739
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 7.407505956 2727394
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 6.0117160924
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.6116129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1616835633
MESH:D002779 Cholestasis pirinixic acid 2.8319176532
MESH:D002822 Choriocarcinoma Tretinoin 5.1916461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.7716354765 15668235 8697196 15340226 12621046
MESH:D002972 Cleft Palate Tretinoin 5.779407595
MESH:D003092 Colitis Tretinoin 3.7217035595
MESH:D003110 Colonic Neoplasms Quercetin 2.4219056647 17191121 11134977 19440933 15741050 17148506 16640504
MESH:D015179 Colorectal Neoplasms Paclitaxel 2.8318802399
MESH:D015179 Colorectal Neoplasms Quercetin 2.8318852136 18095365
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0614669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4520055451 15322242 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.458800419 9142499 10589399 9211117 17551590 9224671 9125849 9664655 14991402 16925845
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3819031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4318249437
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.7319496084
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6717107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.4819279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.5619923254 11834606 19739265 14986274 14725611 17906064 11739529 16177239 14550746 18071297 16393943 12594235 12392966 12958197 11743745 11287661 17562736 19085960 2444490 19420014 10774834 10915739 12540782 16227642 19370779 15968718 16485898 19164858 11461765 16081117 18713872 12705907 15619225 11421492 16781746 16109766 19416960 17522070 11529661 10663392 12153990
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.5620420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1319426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7611462148
MESH:D050171 Dyslipidemias Dietary Fats 3.4518367378
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 6.0118357618
MESH:D004487 Edema pirinixic acid 6.5512083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.5512711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 12.0515322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 12.0518230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 3.5519031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.4416202921 17893378 20544844 19155303
MESH:D016889 Endometrial Neoplasms Tretinoin 7.4416569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.0210568697 9294722
MESH:D004938 Esophageal Neoplasms Paclitaxel 2.8916481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.8411564622
MESH:D005124 Eye Abnormalities Tretinoin 8.8416938888 9664655
MESH:D005234 Fatty Liver Dietary Fats 13.1318296743 19551842 17967931 19004024
MESH:D005234 Fatty Liver pirinixic acid 13.1319236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 13.1319224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2416709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4711858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.5514745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.2019069698
MESH:D005354 Fibrosarcoma Methylnitrosourea 5.2511555667
MESH:D005355 Fibrosis Dietary Fats 21.3118296743
MESH:D005355 Fibrosis Quercetin 21.3119474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 21.3120067830
MESH:D005355 Fibrosis Tretinoin 21.3117994277
MESH:D005756 Gastritis Acetaminophen 3.7116983495
MESH:D005909 Glioblastoma Ethylnitrosourea 12.0316436596
MESH:D005909 Glioblastoma Quercetin 12.0319804834
MESH:D005909 Glioblastoma Tretinoin 12.0317312396
MESH:D005910 Glioma Ethylnitrosourea 10.1416357521 18412241 16651633
MESH:D005910 Glioma Methylnitrosourea 10.149825942
MESH:D005910 Glioma Quercetin 10.1417643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6210696789
OMIM:214450 GRISCELLI SYNDROME, TYPE 1 marker/mechanism
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.1916096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.1916084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.5410048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 6.5414991402 9664655
MESH:D006333 Heart Failure pirinixic acid 2.5420558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3411000095
MESH:D006529 Hepatomegaly pirinixic acid 8.3119772884 18467677 19176532 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.3116120746 12621046 15340226
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0816354765 18606429 8697196 16959395 15340226
MESH:D006930 Hyperalgesia Acetaminophen 7.6316870215
MESH:D006930 Hyperalgesia Tretinoin 7.6316870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.6021332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.5816778211
MESH:D006943 Hyperglycemia pirinixic acid 9.2520558911
MESH:D006943 Hyperglycemia Quercetin 9.2511834736 18262572
MESH:D006949 Hyperlipidemias Dietary Fats 3.6221332399
MESH:D006973 Hypertension Quercetin 5.2318356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.2318850075 18670907
MESH:D007248 Infertility, Male Methylnitrosourea 3.807193160
MESH:D007249 Inflammation Dietary Fats 11.9720412841
MESH:D007249 Inflammation Flavonoids 11.9717296493
MESH:D007249 Inflammation Tamoxifen 11.9719457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.9712200463 12878042
MESH:D007251 Influenza, Human Quercetin 4.5416624496
MESH:D007333 Insulin Resistance Dietary Fats 7.2511836018 18457598
MESH:D007333 Insulin Resistance pirinixic acid 7.2516306350
MESH:D007410 Intestinal Diseases Tretinoin 3.7817994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.9516580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.9515992940 17551590
MESH:D007627 Keloid Quercetin 4.9717086741
MESH:D007674 Kidney Diseases Acetaminophen 6.0812587719 15629191
MESH:D007674 Kidney Diseases Quercetin 6.0816962696
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 7.7517379185
MESH:D007680 Kidney Neoplasms Tamoxifen 7.7518625569
MESH:D007938 Leukemia Quercetin 6.4617468513
MESH:D007938 Leukemia Tretinoin 6.4617143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.7019285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0819850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.1517506722 17712046 17368321 17107899 17301526 19035177 16935935 16766008 19225113 17649720 12679006 19642359 19075265 16331271 16891316 9834237 19029980 16788101 17217047 17339181 16140955 17294898 17361223 16823087 15748426
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 8.4715526292
MESH:D017880 Limb Deformities, Congenital Tretinoin 8.479224671
MESH:D008064 Lipidoses Tamoxifen 3.1617567588 15342952
MESH:D008080 Liposarcoma Paclitaxel 4.8317353645
MESH:D008103 Liver Cirrhosis Dietary Fats 2.8818296743
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.7415474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 6.7412741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 6.7418564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.7412878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.7416248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 1.6312969438 19460945 19784758 19014921 16611625 16610002 11587558 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2417185352 16871587
MESH:D008113 Liver Neoplasms pirinixic acid 10.7016377806 20007298 15890375
MESH:D008113 Liver Neoplasms Quercetin 10.7018980244
MESH:D008113 Liver Neoplasms Tamoxifen 10.7016684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.7016984957
MESH:D008114 Liver Neoplasms, Experimental Quercetin 5.9319519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 5.9312151625
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 5.4816080182
MESH:D008175 Lung Neoplasms Asbestos 8.5912111688
MESH:D008175 Lung Neoplasms Ethylnitrosourea 8.596695378 16271038 17703301 16019985
MESH:D008175 Lung Neoplasms Methylnitrosourea 8.5918062963
MESH:D008175 Lung Neoplasms Quercetin 8.5916280456
MESH:D008175 Lung Neoplasms Tamoxifen 8.5918625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.5911884234 19555203
MESH:D008223 Lymphoma Chlorambucil 12.9810745627
MESH:D008223 Lymphoma Ethylnitrosourea 12.9815790496
MESH:D008223 Lymphoma Methylnitrosourea 12.9816257854 11418001
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 4.7814633661
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 4.0914749477
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 5.0615375218
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.7819428831
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 10.2110838139 18041768 10767621
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 10.2110838139 10767621 14633655 15113128 16827153 16944150 19196723 15313902 16051031 11751437 17131329 15688392 17020996 11807958 14999141 12931682 16619500
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 10.2116827153 11731420 19196723 14580682 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.5819453300
MESH:D008527 Medulloblastoma Tretinoin 2.7817453147
MESH:D008545 Melanoma Paclitaxel 5.1712025231 16342250 12040289
MESH:D008545 Melanoma Tamoxifen 5.1719393235 12393984
MESH:D008545 Melanoma Tretinoin 5.1716752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.2015990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5819513568
MESH:D008579 Meningioma Ethylnitrosourea 6.0117943659
MESH:D008591 Meningomyelocele Tretinoin 4.4416940565
MESH:D008654 Mesothelioma Asbestos 4.0818709470 18310086 16919927 16319530 16564556
MESH:D009101 Multiple Myeloma Paclitaxel 3.6914749477
MESH:D009135 Muscular Diseases pirinixic acid 3.5216239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.0817596541
MESH:D009203 Myocardial Infarction pirinixic acid 5.7319151258
MESH:D009203 Myocardial Infarction Quercetin 5.7319595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0212213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.4416411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 8.4419207477
MESH:D009362 Neoplasm Metastasis Paclitaxel 5.9915867366
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.9919393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5219410462
MESH:D009369 Neoplasms Methylnitrosourea 11.9315533788
MESH:D009369 Neoplasms pirinixic acid 11.9317405874
MESH:D009369 Neoplasms Quercetin 11.9315185748
MESH:D009369 Neoplasms Tretinoin 11.9316946489 16594593
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 9.7216707424
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 9.7212696579
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.0319189210 19200415 19196722
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.5414600291
MESH:D009421 Nervous System Malformations Tretinoin 9.549125849
MESH:D009436 Neural Tube Defects Tretinoin 3.059142499
MESH:D009442 Neurilemmoma Ethylnitrosourea 13.3517160924 16003739 16651423
MESH:D009442 Neurilemmoma Methylnitrosourea 13.3511555667
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8718514411
MESH:D020078 Neurogenic Inflammation Quercetin 4.3717929310
MESH:D009765 Obesity Dietary Fats 4.4421332399 18674790 17217161 11836018 18457598 19632207 16723640 20518802 20132043
MESH:D009765 Obesity pirinixic acid 4.4420558911
MESH:D009837 Oligodendroglioma Ethylnitrosourea 6.0117160924
MESH:D010014 Osteolysis Paclitaxel 5.0015867366
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.2219495926
MESH:D010051 Ovarian Neoplasms Paclitaxel 8.0311161223
MESH:D010051 Ovarian Neoplasms Quercetin 8.0319005980
MESH:D010051 Ovarian Neoplasms Tretinoin 8.0316936753
MESH:D010146 Pain Acetaminophen 6.5916870215
MESH:D010146 Pain Tretinoin 6.5916870215
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 8.7916965848
MESH:D010190 Pancreatic Neoplasms Quercetin 8.7916965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 8.7915976015
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2812520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5718163543
MESH:D011230 Precancerous Conditions Quercetin 3.9819056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2111399792 11896295 11222880 11118676
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 2.1615682402 12376480
MESH:D011471 Prostatic Neoplasms Paclitaxel 2.1616356831 17172428 17136230 16729912
MESH:D011471 Prostatic Neoplasms Quercetin 2.1617292933 14715546
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.1615067354
MESH:D011507 Proteinuria Tretinoin 3.6116636307
MESH:D011625 Pterygium Tretinoin 4.8116723453
MESH:D015427 Reperfusion Injury pirinixic acid 2.3919058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8518990726
MESH:D012162 Retinal Degeneration Methylnitrosourea 4.4118172121 18155124
MESH:D012175 Retinoblastoma Methylnitrosourea 5.5111555667
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.1116283617 16116481
MESH:D012554 Schistosomiasis japonica Quercetin 5.5816862918
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 9.448532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.4416192470
MESH:D012878 Skin Neoplasms Tretinoin 9.4416467112
MESH:D013088 Spermatocele Tamoxifen 4.3216709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0619457130
MESH:D013274 Stomach Neoplasms Methylnitrosourea 3.5718593901 16257854 15930296
MESH:D013274 Stomach Neoplasms Paclitaxel 3.5718506536 18396642
MESH:D013274 Stomach Neoplasms Tretinoin 3.5717261132
MESH:D024801 Tauopathies Paclitaxel 4.8316930453
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 12.3715790496
MESH:D013953 Thymus Neoplasms Methylnitrosourea 12.3711418001
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9312697716
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 7.523078959 7505956
MESH:D013964 Thyroid Neoplasms Tretinoin 7.5216026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.7916051514
MESH:D014376 Tuberculosis Tretinoin 3.2316040207
MESH:D001749 Urinary Bladder Neoplasms Quercetin 5.2316720314
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 5.238653321 16712894 17572228
MESH:D014581 Urticaria Acetaminophen 2.9810982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.6816129372
MESH:D014604 Uveal Neoplasms Tretinoin 4.6416752155
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6212125929
MESH:D014820 Vitiligo Tretinoin 4.0716761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2815886252
MESH:D015430 Weight Gain Dietary Fats 3.7416723640
MESH:D009396 Wilms Tumor Tretinoin 3.9716287080
Pathway ID Pathway Name
REACT:15380 Diabetes pathways
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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