AutismKB 2.0

Annotation Detail for MYO7B


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Basic Information Top
Gene Symbol:MYO7B ( DKFZp686A08248 )
Gene Full Name: myosin VIIB
Band: 2q14.3
Quick LinksEntrez ID:4648; OMIM: 606541; Uniprot ID:MYO7B_HUMAN; ENSEMBL ID: ENSG00000169994; HGNC ID: 7607
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
P00044Nicotinic acetylcholine receptor signaling pathway
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of MYO7B mRNAaffects expression 17555576
D013629 Tamoxifen Tamoxifen affects the expression of MYO7B mRNAaffects expression 17555576
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 5.6214745880
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 5.0117505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.9014692618
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.2311256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.9315885639
MESH:D001943 Breast Neoplasms Tamoxifen 2.1619011961 19142967 19084267 19103187 20544844 20859285 21152245 16202921 18815881 21138602 19189212 18984771 20390343 19059307 18351453 19487384 20135344 16273361 17893378 18855134 19115204 20065188 19189210 16818667 19155303 18629630 19221464 19288272 17261762 19244106 19200415 17440819 15565566 18425577 15668708 19066611 11161223 18997820 17049068 19410462 20005174 16873071 17242785 18821012 19289846
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 5.2719066611
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 1.8616924424
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 4.1217572228
MESH:D002779 Cholestasis Ethinyl Estradiol 3.2416105132 17110522 16919318 17333356 17681005 15861022 11677210
MESH:D003711 Demyelinating Diseases Tamoxifen 5.1319031437
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.9419279558
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 11.2912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 11.2919031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.3417893378 19155303 20544844 16202921
MESH:D005234 Fatty Liver Ethinyl Estradiol 9.5815345470
MESH:D005234 Fatty Liver Tamoxifen 9.5819224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.5016709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 5.4114745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 5.0719069698
MESH:D007021 Hypospadias Ethinyl Estradiol 4.5716945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 4.0712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7917937319
MESH:D007249 Inflammation Tamoxifen 2.5719457130
MESH:D007680 Kidney Neoplasms Tamoxifen 3.4718625569
MESH:D008064 Lipidoses Tamoxifen 3.5015342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 1.7518564211
MESH:D008113 Liver Neoplasms Tamoxifen 2.3516684651
MESH:D008175 Lung Neoplasms Tamoxifen 1.7518625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.6419428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.9114580682 19196722 11731420 19196723 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 5.6219453300
MESH:D008545 Melanoma Tamoxifen 1.9312393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 5.0715990972
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.7019393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.6319410462
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 5.0719189210 19196722 19200415
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.2911578682
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.0715067354
MESH:D011537 Pruritus Ethinyl Estradiol 4.2015861022 16919318
MESH:D013088 Spermatocele Ethinyl Estradiol 15.5716709447
MESH:D013088 Spermatocele Tamoxifen 15.5716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.9219457130
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.2311994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.6215669648
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 2.508653321 16712894 17572228
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.9714692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 4.0914671159 15869587
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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