AutismKB 2.0

Annotation Detail for MYO9A


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Basic Information Top
Gene Symbol:MYO9A ( FLJ11061,FLJ13244,MGC71859 )
Gene Full Name: myosin IXA
Band: 15q23
Quick LinksEntrez ID:4649; OMIM: 604875; Uniprot ID:MYO9A_HUMAN; ENSEMBL ID: ENSG00000066933; HGNC ID: 7608
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Signaling by Rho GTPases
No data
Pathway IDPathway Name
P00044Nicotinic acetylcholine receptor signaling pathway
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MYO9A mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of MYO9A mRNAdecreases expression 20064835
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of MYO9A mRNAaffects cotreatment|increases expression 20360939
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of MYO9A mRNAaffects cotreatment|increases expression 20360939
D018038 Sodium Selenite Sodium Selenite results in increased expression of MYO9A mRNAincreases expression 18175754
C004648 testosterone enanthate testosterone enanthate affects the expression of MYO9A mRNAaffects expression 17440010
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.0218287403
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0420127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 7.196695378
MESH:D000236 Adenoma Diethylnitrosamine 7.196695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 4.3616434500 17620307 18056438 19061943 17162532 19052882
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.4919183758
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0620146248 17474063
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.0617474063
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 1.8717055752 18785209 19208518 19539802 17761372 16779866 16878318 11831363 18788625 16698587 20512989 20935162 19701751 19418558 20727157 16288022 16502159 10737359 19107877 20432363 20514400 17428255 18210153 16540662 20214788 18665156 17162532 20524982 18978308 21159647 19052882 17138121 18494052 18971187 3084413 20084675 16569478 3581430 18393292 16681979 19919837 19394651 18506893 17173139 20101231 19335982 10672840 18691550 16328049 19171122 16935385 19519916 19383236 18056438 20007298 16807293 17978847 19822196 16830150
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1220419170
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 3.0621159647 2727394 17174075 7505956
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.9719052882
MESH:D019457 Chromosome Breakage Sodium Selenite 5.1715894690
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.0616285004
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2520387270
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 4.2519107877
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 4.2515131321
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.6416302075
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0716530937
MESH:D005234 Fatty Liver Diethylnitrosamine 3.5120387270 21071580
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8020471113
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 6.2717440010
MESH:D007249 Inflammation Diethylnitrosamine 2.5218785209
MESH:D007333 Insulin Resistance Sodium Selenite 3.4714714311
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.8910783313
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 3.7115369732
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 4.1816766008
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.9818665156 19638242 18522880 20032147 18407596
MESH:D008107 Liver Diseases Diethylnitrosamine 2.1617034775
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.8520195826 21137059
MESH:D008113 Liver Neoplasms Diethylnitrosamine 4.8520434301 19551842 19499222 19255062 19426721 12112319 19638242 20118626 18644402 19427195 19850985 19256749 18977376 12771043 18754104 9163691 19254457 18978307 20452335 19833225 15885732 20501860 15175105 19073162 19294768 16942905 18648771 20137499 20101389 2862719 21278145 20583210 19812893 19690152 21167192 19090486 2422723 20405173 19642983 10737359 20492335 21071580 19996281 21047994
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 2.8118308698 19519916 19009564 19126423 19539802 18093689 18079962 18253720 21159647 18282651 17854601 19004024 18775883 17942915 18544905 9362446 16267830 18164116 16842330 2563599 17174075 3124819
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.4520135361 18520028 20064080 20464547 20869020 18816296 18569708 17053015 6695378
MESH:D008175 Lung Neoplasms Diethylnitrosamine 2.4520970405 21163286 6695378 20512841
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.4114737004
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4316381670
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.679029167 3581430
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3011141357
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.6120387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.6420387270
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.5116540662
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.842563599
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.1517292933
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.1518760546
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.4910029692 19755658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.3920155912 2093021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.3918456281
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 3.227505956
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2817053015
Pathway ID Pathway Name
REACT:11044 Signaling by Rho GTPases
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018