AutismKB 2.0

Annotation Detail for MYOG


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Basic Information Top
Gene Symbol:MYOG ( MYF4,MYOGENIN,bHLHc3 )
Gene Full Name: myogenin (myogenic factor 4)
Band: 1q32.1
Quick LinksEntrez ID:4656; OMIM: 159980; Uniprot ID:MYOG_HUMAN; ENSEMBL ID: ENSG00000122180; HGNC ID: 7612
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
Myogenesis
Pathway IDPathway Name
200106Regulation of Wnt-mediated beta catenin signaling and target gene transcription
No data
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Related Diseases/Disorders Top
No data
Desease IDDesease Name
2035Brain disease
2224Rhabdomyosarcoma
No data
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C055506 4-(diethylamino)benzaldehyde 4-(diethylamino)benzaldehyde results in decreased expression of MYOG proteindecreases expression 16316642
D013196 Dihydrotestosterone Dihydrotestosterone results in increased expression of MYOG proteinincreases expression 17440010
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MYOG mRNAaffects expression 16483693
D001374 Azacitidine Azacitidine results in increased expression of MYOG mRNAincreases expression 18938140
D002045 Bupivacaine Bupivacaine results in decreased expression of MYOG proteindecreases expression 10434046
D002330 Carmustine Carmustine results in decreased expression of MYOG mRNAdecreases expression 15980968
C059514 resveratrol resveratrol results in decreased expression of MYOG mRNAdecreases expression 17588540
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of MYOG mRNAincreases expression 16714409
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of MYOG mRNAincreases expression 15328365
D014212 Tretinoin Tretinoin results in increased expression of MYOG proteinincreases expression 16316642
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.1311752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.8418287403
MESH:D058186 Acute Kidney Injury resveratrol 4.0616538975
MESH:D000236 Adenoma resveratrol 3.4215688382
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.6616835633
MESH:D000505 Alopecia Tretinoin 3.7815955085
MESH:D000544 Alzheimer Disease resveratrol 2.6016162502 16183991
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.1411748828
MESH:D001169 Arthritis, Experimental resveratrol 7.9117115116
MESH:D001169 Arthritis, Experimental Tretinoin 7.9116412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.3016292516
MESH:D001249 Asthma Tretinoin 2.3916456186
MESH:D050197 Atherosclerosis resveratrol 3.3817967414 16873680
MESH:D001471 Barrett Esophagus Tretinoin 4.6416935849
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.6312125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 9.6316206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.1115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8915746008
MESH:D002545 Brain Ischemia resveratrol 4.5717600658
MESH:D001932 Brain Neoplasms Carmustine 4.5816187019
MESH:D001943 Breast Neoplasms resveratrol 1.8917651959 16393696 17534123
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8920435547
MESH:D001943 Breast Neoplasms Tretinoin 1.8916166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.8816813970
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.9616835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.4816168501
MESH:D006528 Carcinoma, Hepatocellular resveratrol 3.2919321006 16227395
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 3.291917145
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.8816675471
MESH:D002294 Carcinoma, Squamous Cell resveratrol 4.9816227395
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.9816096774 16051514
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4718850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases resveratrol 3.6115458977
MESH:D002386 Cataract Tretinoin 3.2017460283
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.8816129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.3416835633
MESH:D002822 Choriocarcinoma Tretinoin 5.4816461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 6.0215668235 8697196 12621046 16354765 15340226
MESH:D002972 Cleft Palate Tretinoin 6.029407595
MESH:D003092 Colitis resveratrol 10.5016474422
MESH:D003092 Colitis Tretinoin 10.5017035595
MESH:D003110 Colonic Neoplasms resveratrol 2.4816338953
MESH:D015179 Colorectal Neoplasms Azacitidine 2.9819934284
MESH:D015179 Colorectal Neoplasms resveratrol 2.9816550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.2417141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.8716507316
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.5015322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.509664655 17551590 9224671 16925845 8800419 10589399 9125849 14991402 9211117 9142499
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.9416873680
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7117107852
MESH:D003928 Diabetic Nephropathies resveratrol 4.1416286809
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 1.5820420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9111462148
MESH:D004487 Edema resveratrol 7.558985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 7.5512711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 13.0315322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 13.0318230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 4.2617872969
MESH:D016889 Endometrial Neoplasms Tretinoin 3.2316569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.2110568697 9294722
MESH:D020345 Enterocolitis, Necrotizing resveratrol 5.1117923197
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 9.3411564622
MESH:D005124 Eye Abnormalities Tretinoin 9.3416938888 9664655
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.7111858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 9.5020067830
MESH:D005355 Fibrosis Tretinoin 9.5017994277
MESH:D005909 Glioblastoma Carmustine 7.8816187019
MESH:D005909 Glioblastoma Tretinoin 7.8817312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.9110696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.3216096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.4816084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.8611294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 6.869664655 14991402
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.5411000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.1515340226 16120746 12621046
MESH:D006561 Herpes Simplex resveratrol 4.4616876885
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.3616354765 8697196 16959395 15340226 18606429
MESH:D006930 Hyperalgesia Tretinoin 3.3716870215
MESH:D006937 Hypercholesterolemia resveratrol 4.2117188708
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.8316778211
MESH:D006949 Hyperlipidemias resveratrol 4.2516873680
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9718670907 18850075
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.5017488730
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.9117600658
MESH:D007249 Inflammation Bupivacaine 9.2218165598
MESH:D007249 Inflammation resveratrol 9.2216366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 9.2212200463 12878042
MESH:D007251 Influenza, Human resveratrol 4.8616624496
MESH:D007410 Intestinal Diseases Tretinoin 4.0217994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 10.6316580747
MESH:D007569 Jaw Abnormalities Tretinoin 10.6315992940 17551590
MESH:D007938 Leukemia Azacitidine 6.9619148494
MESH:D007938 Leukemia Tretinoin 6.9617143497
MESH:D007951 Leukemia, Myeloid Azacitidine 10.4919077051
MESH:D007951 Leukemia, Myeloid Tretinoin 10.4919285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 4.3017596541 18720364
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 4.3017596541 16294345 19850784
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 5.4119299654
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 8.1916087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 8.1919642359 17217047 16935935 9834237 16823087 17368321 17712046 17506722 17361223 16766008 17294898 19029980 19035177 16331271 19075265 12679006 17649720 19225113 17301526 15748426 16788101 16140955 16891316 17339181 17107899
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.459224671
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.3612878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 2.3618397230 16248980
MESH:D008113 Liver Neoplasms resveratrol 4.8019321006 19812893 20405173 19073162
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.8016984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.2212151625
MESH:D008175 Lung Neoplasms Azacitidine 2.6621224363
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.6611884234 19555203
MESH:D016393 Lymphoma, B-Cell resveratrol 4.5217088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 4.0414749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.5315688416
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 3.2311606380 8985016
MESH:D008527 Medulloblastoma Tretinoin 2.8517453147
MESH:D008545 Melanoma Carmustine 5.4512393984
MESH:D008545 Melanoma resveratrol 5.4517992120
MESH:D008545 Melanoma Tretinoin 5.4516752155
MESH:D008591 Meningomyelocele Tretinoin 4.6816940565
MESH:D008659 Metabolic Diseases resveratrol 4.5817112576
MESH:D009006 Monosomy Azacitidine 6.4019299654
MESH:D009101 Multiple Myeloma Azacitidine 8.2218443271 19549372
MESH:D009101 Multiple Myeloma resveratrol 8.2216490592 17164350 17049120 17935668 14749477 16267019
MESH:D009134 Muscular Atrophy, Spinal resveratrol 5.1617962980
MESH:D009190 Myelodysplastic Syndromes Azacitidine 8.0717611569 18720364 17596541 19805378
MESH:D009190 Myelodysplastic Syndromes Tretinoin 8.0717596541
MESH:D009203 Myocardial Infarction resveratrol 3.1016525036 16317513 16456233 17125593 17015251 17188708
MESH:D017202 Myocardial Ischemia resveratrol 9.5617125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 9.5612213967
MESH:D009205 Myocarditis resveratrol 5.0417322642
MESH:D009369 Neoplasms Tretinoin 2.4916946489 16594593
MESH:D009374 Neoplasms, Experimental resveratrol 4.268985016
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 10.3214600291
MESH:D009421 Nervous System Malformations Tretinoin 10.329125849
MESH:D009436 Neural Tube Defects Tretinoin 3.189142499
MESH:D019636 Neurodegenerative Diseases resveratrol 3.9817652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.6217929310
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.4817513867
MESH:D010051 Ovarian Neoplasms Tretinoin 2.4016936753
MESH:D010146 Pain Tretinoin 3.0716870215
MESH:D010149 Pain, Postoperative Bupivacaine 6.7118165598
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.5215976015
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.5712520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.8018163543
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 10.5616679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 10.5611399792 11118676 11896295 11222880
MESH:D011471 Prostatic Neoplasms Azacitidine 3.6918324645
MESH:D011471 Prostatic Neoplasms resveratrol 3.6915767336 17804756 16731767 17636462 17718901 17675339
MESH:D011507 Proteinuria Tretinoin 3.8216636307
MESH:D011625 Pterygium Tretinoin 5.0816723453
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.9016325855
MESH:D015427 Reperfusion Injury resveratrol 3.3616314181 16317513 17058453 15827377 17520802
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.0818990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.3216116481 16283617
MESH:D012878 Skin Neoplasms resveratrol 9.9815837718 8985016
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.9816192470
MESH:D012878 Skin Neoplasms Tretinoin 9.9816467112
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.6716321402
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.2212697716
MESH:D013964 Thyroid Neoplasms Tretinoin 3.1816026305 17045167
MESH:D014062 Tongue Neoplasms resveratrol 10.5716227395
MESH:D014062 Tongue Neoplasms Tretinoin 10.5716051514
MESH:D014376 Tuberculosis Tretinoin 3.3416040207
MESH:D002583 Uterine Cervical Neoplasms resveratrol 10.1917473185
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 10.1916129372
MESH:D014594 Uterine Neoplasms resveratrol 4.3717044934
MESH:D014604 Uveal Neoplasms Tretinoin 4.9316752155
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.9112125929
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.5617488730
MESH:D014820 Vitiligo Tretinoin 4.2916761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.5715886252
MESH:D009396 Wilms Tumor Tretinoin 4.1516287080
Pathway ID Pathway Name
REACT:21303 Myogenesis
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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