AutismKB 2.0

Annotation Detail for NUBP1


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Basic Information Top
Gene Symbol:NUBP1 ( MGC117406,MGC130052,MGC130053,NBP,NBP1 )
Gene Full Name: nucleotide binding protein 1 (MinD homolog, E. coli)
Band: 16p13.13
Quick LinksEntrez ID:4682; OMIM: 600280; Uniprot ID:NUBP1_HUMAN; ENSEMBL ID: ENSG00000103274; HGNC ID: 8041
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of NUBP1 mRNAaffects expression 17562736
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of NUBP1 mRNAaffects expression 17484886
C006253 pirinixic acid pirinixic acid results in increased expression of NUBP1 mRNAincreases expression 18301758
D014303 Trinitrotoluene Trinitrotoluene affects the expression of NUBP1 mRNAaffects expression 21346803
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Trinitrotoluene 4.827525203
MESH:D055371 Acute Lung Injury pirinixic acid 3.5818653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.1116434500
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.5719483382
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.3415700767 16124888 15673190 16097048 15721981 10355542 16227642 3786805 16192424 18705752 16050911 16011737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.993084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 2.9918788625
MESH:D002386 Cataract Acetaminophen 8.2110977129
MESH:D002386 Cataract Trinitrotoluene 8.2114694615 15817613
MESH:D002779 Cholestasis pirinixic acid 3.1219176532
MESH:D000013 Congenital Abnormalities Trinitrotoluene 4.7715095906
MESH:D003490 Cyanosis Trinitrotoluene 5.4818551238
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5718249437
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.8612392966 14550746 19370779 19085960 16393943 15968718 12594235 17906064 17562736 10915739 19164858 16081117 10663392 16109766 16485898 11461765 14986274 11834606 11421492 14725611 19420014 16177239 19923254 18071297 17522070 11743745 15619225 19416960 12958197 19739265 12153990 16781746 2444490 16227642 10774834 12540782 18713872 11287661 11529661 11739529 12705907
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 6.8611566570 15968718 6884620 7440962 7179309 19085960 15027814 21278145 3732212 17522070 6623471 9327722 15998439 7120509 10092053 16227642 2869522 19336974 16177239 4309450 3786805 10915739
MESH:D056486 Drug-Induced Liver Injury Trinitrotoluene 6.8618551238 21346803
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D004487 Edema pirinixic acid 2.9012083418
MESH:D005234 Fatty Liver Carbon Tetrachloride 9.1261145 12631006 16045604 12795759 19224547 17595544 15959796 16239168
MESH:D005234 Fatty Liver pirinixic acid 9.1219236843 20131406
MESH:D005355 Fibrosis Carbon Tetrachloride 4.0118705752
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D006333 Heart Failure pirinixic acid 2.7620558911
MESH:D006505 Hepatitis Carbon Tetrachloride 4.1019900420 19110552
MESH:D006529 Hepatomegaly pirinixic acid 10.6918467677 16221962 19772884 19176532
MESH:D006529 Hepatomegaly Trinitrotoluene 10.6915817613
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.1616899240
MESH:D006943 Hyperglycemia pirinixic acid 3.5820558911
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.6515338365
MESH:D007248 Infertility, Male Trinitrotoluene 3.9212150543
MESH:D007333 Insulin Resistance pirinixic acid 2.8716306350
MESH:D007674 Kidney Diseases Acetaminophen 2.4015629191 12587719
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 3.0016221502 16239168 11408273 17334410 17174718 11903743 16943688 17157831 21278145
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 2.4115996030 16097048 20821823 15730626 12445421 16015684 17631135 12666154 16027843 17481882 17944888 17823541 15650968 14512876 18251166 15370692 15876570 15052691 18317297 17922224 17766677 16248980 12632512 18472332 18395914 14716496 17525996 18210741 17976157 18263696 18376398 18006644 12546737 12649538 17721639 14620537 18420326 15925388 17557913 15959796 12958196 17761835 12586293 16136751 18166357 12389079 18395095 15818738 18187930 16033810 18339082 18472094 18279442 15931870 12898905 16638106 18412020 18054572 18418968 17698563 12667390 17900296 15123356 14716833 17565644 17805973 18429990 14748882 16192424 15338365 13678700 12632514 14724832 17708605 18156304 18277467 16011737 15673190 15057751 17869086 16116963 12445418 10355542 15362042 12609069 18205269 12741479 15893842 17714472 18481824 17640975 11481614 18705752
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.4115474484
MESH:D008107 Liver Diseases Acetaminophen 4.1616611625 19460945 16610002 12969438 11587558 19014921 12587719 19784758
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.1617285989 15830285 16964402 16246199 15720792
MESH:D017093 Liver Failure Carbon Tetrachloride 4.7315123358
MESH:D017114 Liver Failure, Acute Acetaminophen 10.7516871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 10.7516899240 14706259
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 4.8419294768
MESH:D008113 Liver Neoplasms pirinixic acid 4.8416377806 15890375 20007298
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.8412014681 15583823
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D009135 Muscular Diseases pirinixic acid 4.0716239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2719151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2516411023
MESH:D009336 Necrosis Trinitrotoluene 5.4018551238
MESH:D009369 Neoplasms pirinixic acid 2.1117405874
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D009765 Obesity pirinixic acid 1.8820558911
MESH:D009784 Occupational Diseases Trinitrotoluene 4.7312819281 17852074 14694615
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D015427 Reperfusion Injury pirinixic acid 2.5519058328
MESH:D012640 Seizures Trinitrotoluene 3.6918551238
MESH:D013163 Splenomegaly Trinitrotoluene 5.7615817613
MESH:D014581 Urticaria Acetaminophen 3.4410982225
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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