AutismKB 2.0

Annotation Detail for NCF2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NCF2 ( FLJ93058,NCF-2,NOXA2,P67-PHOX,P67PHOX )
Gene Full Name: neutrophil cytosolic factor 2
Band: 1q25.3
Quick LinksEntrez ID:4688; OMIM: 608515; Uniprot ID:NCF2_HUMAN; ENSEMBL ID: ENSG00000116701; HGNC ID: 7661
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04670Leukocyte transendothelial migration
hsa04145Phagosome
hsa05140Leishmaniasis
No data
Pathway IDPathway Name
200190RAC1 signaling pathway
No data
No data
Related Diseases/Disorders Top
Desease IDDesease Name
H00098Chronic granulomatous disease
Immune system diseases
Primary immunodeficiency
Desease IDDesease Name
1857Porcine reproductive and respiratory syndrome
1918Atherosclerosis
1959Granulomatous disease
No data
No data
Desease Name
Chronic granulomatous disease due to deficiency of NCF-2
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C026114 2-xylene 2-xylene results in increased expression of NCF2 mRNAincreases expression 20359517
C056165 acetovanillone acetovanillone inhibits the reaction [LEP protein results in increased expression of NCF2 protein]decreases reaction|increases expression 16380530
D000171 Acrolein Acrolein inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCF2 protein]affects localization|decreases reaction 11246141
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of NCF2 proteinaffects expression 20106945
D016718 Arachidonic Acid Arachidonic Acid affects the reaction [Zymosan analog affects the localization of NCF2 protein]affects localization|affects reaction 12101222
C006632 arsenic trioxide arsenic trioxide results in increased expression of NCF2 proteinincreases expression 15070760
C015001 arsenite arsenite results in increased expression of NCF2 mRNAincreases expression 18929588
C015001 arsenite TRP53 protein affects the reaction [arsenite results in increased expression of NCF2 mRNA]affects reaction|increases expression 18929588
D001554 Benzene Benzene results in increased expression of NCF2 mRNAincreases expression 20359517
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of NCF2 mRNAincreases expression 20106945
C006780 bisphenol A bisphenol A results in increased expression of NCF2 mRNAincreases expression 14555285
C086539 BQ 788 BQ 788 inhibits the reaction [LEP protein results in increased expression of NCF2 protein]decreases reaction|increases expression 16380530
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of NCF2 mRNAincreases expression 17854599
D016572 Cyclosporine Cyclosporine results in increased expression of NCF2 mRNAincreases expression 20106945
C072247 cyclo(Trp-Asp-Pro-Val-Leu) cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [LEP protein results in increased expression of NCF2 protein]decreases reaction|increases expression 16380530
D004958 Estradiol Estradiol affects the expression of NCF2 mRNAaffects expression 14699072
D004958 Estradiol Estradiol results in increased expression of NCF2 mRNAincreases expression 20106945
D004958 Estradiol Estradiol affects the expression of NCF2 mRNAaffects expression 16195479
D004958 Estradiol Estradiol inhibits the reaction [Progesterone results in increased expression of NCF2 mRNA]decreases reaction|increases expression 16195479
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of NCF2 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NCF2 mRNAaffects cotreatment|increases expression 17942748
C004912 ethylbenzene ethylbenzene results in increased expression of NCF2 mRNAincreases expression 20359517
D017313 Fenretinide Fenretinide results in increased expression of NCF2 proteinincreases expression 16077929
15059897
D008752 Methylene Chloride Methylene Chloride results in increased expression of NCF2 mRNAincreases expression 20359517
C052753 nebivolol nebivolol inhibits the reaction [AGT protein affects the localization of NCF2 protein]affects localization|decreases reaction 16940222
C052753 nebivolol nebivolol inhibits the reaction [AGT protein results in increased expression of NCF2 protein]decreases reaction|increases expression 16940222
D019787 Linoleic Acid Linoleic Acid affects the reaction [Zymosan analog affects the localization of NCF2 protein]affects localization|affects reaction 12101222
D010269 Paraquat Paraquat affects the localization of NCF2 proteinaffects localization 17662968
D010269 Paraquat rottlerin inhibits the reaction [Paraquat affects the localization of NCF2 protein]affects localization|decreases reaction 17662968
D052638 Particulate Matter NCF2 protein affects the reaction [Particulate Matter results in increased expression of IL6 mRNA]affects reaction|increases expression 19371610
D052638 Particulate Matter NCF2 protein affects the reaction [Particulate Matter results in increased phosphorylation of MAPK1 protein]affects reaction|increases phosphorylation 19371610
D052638 Particulate Matter NCF2 protein affects the reaction [Particulate Matter results in increased phosphorylation of MAPK3 protein]affects reaction|increases phosphorylation 19371610
D052638 Particulate Matter NCF2 protein affects the susceptibility to Particulate Matteraffects response to substance 19371610
D052638 Particulate Matter Particulate Matter affects the localization of NCF2 proteinaffects localization 19371610
D011374 Progesterone Estradiol inhibits the reaction [Progesterone results in increased expression of NCF2 mRNA]decreases reaction|increases expression 16195479
D011374 Progesterone Progesterone results in increased expression of NCF2 mRNAincreases expression 16195479
D020849 Raloxifene ESR2 protein affects the reaction [Raloxifene results in decreased expression of NCF2 mRNA]affects reaction|decreases expression 14699072
D020849 Raloxifene Raloxifene affects the expression of NCF2 mRNAaffects expression 14699072
D020849 Raloxifene [Raloxifene co-treated with ESR2 protein] results in decreased expression of NCF2 mRNAaffects cotreatment|decreases expression 19059307
C089730 rosiglitazone rosiglitazone results in decreased expression of NCF2 mRNAdecreases expression 17255338
C089730 rosiglitazone rosiglitazone results in decreased expression of NCF2 proteindecreases expression 17255338
C085746 rottlerin rottlerin inhibits the reaction [Paraquat affects the localization of NCF2 protein]affects localization|decreases reaction 17662968
C017947 sodium arsenite sodium arsenite results in increased phosphorylation of NCF2 proteinincreases phosphorylation 19414066
D013629 Tamoxifen Tamoxifen affects the expression of NCF2 mRNAaffects expression 14699072
D013629 Tamoxifen [Tamoxifen co-treated with ESR2 protein] results in decreased expression of NCF2 mRNAaffects cotreatment|decreases expression 19059307
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of NCF2 mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NCF2 mRNAaffects cotreatment|increases expression 17942748
D013755 Tetradecanoylphorbol Acetate Acrolein inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCF2 protein]affects localization|decreases reaction 11246141
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate affects the localization of NCF2 proteinaffects localization 11246141
D014050 Toluene Toluene results in increased expression of NCF2 mRNAincreases expression 20359517
D014212 Tretinoin Tretinoin results in increased expression of NCF2 mRNAincreases expression 16249480
D014241 Trichloroethylene Trichloroethylene results in increased expression of NCF2 mRNAincreases expression 20359517
C030665 triphenyltin triphenyltin results in increased expression of NCF2 mRNAincreases expression 12788061
D015054 Zymosan Arachidonic Acid affects the reaction [Zymosan analog affects the localization of NCF2 protein]affects localization|affects reaction 12101222
D015054 Zymosan Linoleic Acid affects the reaction [Zymosan analog affects the localization of NCF2 protein]affects localization|affects reaction 12101222
D015054 Zymosan NCF1 protein promotes the reaction [Zymosan analog affects the localization of NCF2 protein]affects localization|increases reaction 12101222
D015054 Zymosan PLA2G4A protein promotes the reaction [Zymosan analog affects the localization of NCF2 protein]affects localization|increases reaction 12101222
D015054 Zymosan Zymosan analog affects the localization of NCF2 proteinaffects localization 12101222
D015054 Zymosan Zymosan analog promotes the reaction [NCF1 protein binds to NCF2 protein]affects binding|increases reaction 12101222
D015054 Zymosan Zymosan analog results in increased phosphorylation of NCF2 proteinincreases phosphorylation 12101222
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1714745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.4915322242 11752688 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5717505938
MESH:D055371 Acute Lung Injury Acrolein 8.9321297076 20525806
MESH:D055371 Acute Lung Injury Particulate Matter 8.9312396868
MESH:D000230 Adenocarcinoma arsenic trioxide 12.4311798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 12.4320127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 12.4311473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 12.4314692618
MESH:D000230 Adenocarcinoma Fenretinide 12.4310697514
MESH:D000236 Adenoma Benzo(a)pyrene 2.446695378
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.0116835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.3215276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.5316712894 17306315
MESH:D000382 Agricultural Workers' Diseases Paraquat 3.4011874814
MESH:D000419 Albuminuria Raloxifene 4.2517451421 17308373
MESH:D000505 Alopecia Tretinoin 3.3315955085
MESH:D000544 Alzheimer Disease Acrolein 8.8117570602 15207723 14715435
MESH:D000544 Alzheimer Disease Particulate Matter 8.8115513908
MESH:D000544 Alzheimer Disease Raloxifene 8.8115800139
MESH:D000544 Alzheimer Disease rosiglitazone 8.8119621015
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.9411748828
MESH:D000740 Anemia Zymosan 7.9418664788
MESH:D000741 Anemia, Aplastic Benzene 4.0917661222 14761424 11369114
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.7119183758
MESH:D001161 Arteriosclerosis Acrolein 9.1315014928
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.1311256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 11.0315885639
MESH:D001169 Arthritis, Experimental Tretinoin 11.0316412693
MESH:D001169 Arthritis, Experimental Zymosan 11.0315142272 17659584 15944321 16872482 15188379
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.1716292516
MESH:D001249 Asthma Tretinoin 2.2316456186
MESH:D050197 Atherosclerosis Acrolein 3.7616037261 17363696 16126721
MESH:D001321 Autistic Disorder Arachidonic Acid 3.0418582451
MESH:D001321 Autistic Disorder Linoleic Acid 3.0418582451
MESH:D001471 Barrett Esophagus Tretinoin 4.0516935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 13.4416206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.4412125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 13.4416206674 16197459
MESH:D001836 Body Weight Changes 2-xylene 10.857457028
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 10.8515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5315746008
MESH:D001855 Bone Marrow Diseases Benzene 4.8616183116
MESH:D001862 Bone Resorption bisphenol A 3.5411985600
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.9617868700
MESH:D001930 Brain Injuries Progesterone 9.7715665606 15380490 15845082
MESH:D001930 Brain Injuries Raloxifene 9.7716580743
MESH:D001932 Brain Neoplasms Fenretinide 4.0416187019
MESH:D001943 Breast Neoplasms Benzene 9.1317162533 11921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 9.1320146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 9.1317123778
MESH:D001943 Breast Neoplasms Estradiol 9.1317018787 12948864 17289903 18497071 17261762 16675129 14630087 19861407
MESH:D001943 Breast Neoplasms Fenretinide 9.1316601279
MESH:D001943 Breast Neoplasms Methylene Chloride 9.1315986119
MESH:D001943 Breast Neoplasms Progesterone 9.1316175315 15562024 17614352
MESH:D001943 Breast Neoplasms Raloxifene 9.1317952589 15758505 17440819 16912660 15572757 17893378 17595753 17049068 17261762 16837676 17242785 15775269
MESH:D001943 Breast Neoplasms Tamoxifen 9.1320005174 19142967 18984771 16202921 17440819 17893378 20859285 19221464 18425577 19189210 19059307 11161223 19288272 19487384 19289846 19011961 16818667 21138602 19244106 19410462 21152245 15565566 18997820 17261762 19200415 18351453 20065188 19115204 18629630 20544844 19103187 17049068 17242785 18855134 16873071 19189212 19155303 18815881 18821012 20135344 16273361 19084267 19066611 15668708 20390343
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 9.1320435547
MESH:D001943 Breast Neoplasms Tretinoin 9.1316873071 16166294 16443354
MESH:D001943 Breast Neoplasms Trichloroethylene 9.1315986119
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2216813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.9911589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0916111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.4218705752 10355542 16011737 15700767 16050911 15721981 3786805 15673190 16192424 16227642 16097048 16124888
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5116835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1519066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.7816168501
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 15.7212619106 12907637 21507988
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 15.7215553829 15073043 16217749 11135700 14691202
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 15.7218788625
MESH:D006528 Carcinoma, Hepatocellular Estradiol 15.7216924424
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 15.7216270382 17159502
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 15.7217306315 16507464 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 15.7216924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 15.721917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.6217123778
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.5019014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.8012490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 13.0920419170
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 13.0916274795
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 13.0918572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 13.0918922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 13.0916096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 8.4417572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 8.4417572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.1616120746 18670907 18850075
MESH:D002318 Cardiovascular Diseases Particulate Matter 7.1612396868
MESH:D002318 Cardiovascular Diseases Raloxifene 7.1615775269
MESH:D002386 Cataract Tretinoin 2.8817460283
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 9.7012371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 9.7018566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 9.7020056578 19524636
MESH:D002547 Cerebral Palsy Toluene 5.489294310
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 11.7516154183
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 11.7516129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.8516835633
MESH:D002779 Cholestasis Cyclosporine 6.8819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 6.8816919318 15861022 11677210 17110522 16105132 17333356 17681005
MESH:D002822 Choriocarcinoma Tretinoin 4.7816461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.2312621046 8697196 16354765 15340226 15668235
MESH:D002972 Cleft Palate Tretinoin 5.239407595
MESH:D003072 Cognition Disorders Raloxifene 4.2615800139
MESH:D003092 Colitis Tretinoin 3.3517035595
MESH:D003110 Colonic Neoplasms arsenite 2.5215037631
MESH:D015179 Colorectal Neoplasms Acrolein 3.4617597105
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.4620501625
MESH:D015179 Colorectal Neoplasms Fenretinide 3.4617273769
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7517141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 3.8412609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 6.8410525206
MESH:D019465 Craniofacial Abnormalities Benzene 6.8415643154
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 6.8415322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Toluene 6.849294310
MESH:D019465 Craniofacial Abnormalities Tretinoin 6.848800419 16925845 14991402 10589399 9224671 17551590 9142499 9211117 9664655 9125849
MESH:D003556 Cystitis Acrolein 5.0212161096
MESH:D003643 Death Toluene 5.296431079
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.7615213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0019031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.8517474826
MESH:D003872 Dermatitis Benzene 4.4115902427
MESH:D003920 Diabetes Mellitus rosiglitazone 3.9917446233
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 4.1612642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.1617107852
MESH:D003928 Diabetic Nephropathies Estradiol 13.2419279558
MESH:D003928 Diabetic Nephropathies Raloxifene 13.2417308373 17451421 15920148
MESH:D003928 Diabetic Nephropathies Tamoxifen 13.2419279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.1317187935
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 5.667440962 6623471 19336974 3786805 17522070 10915739 4309450 7179309 3732212 15998439 2869522 6884620 9327722 10092053 16177239 21278145 15968718 7120509 16227642 11566570 19085960 15027814
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 5.6620420201
MESH:D056486 Drug-Induced Liver Injury Trichloroethylene 5.667120509
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.4911462148
MESH:D004487 Edema Arachidonic Acid 22.837990266 15177302 9599246 11698051 16716910 9831321
MESH:D004487 Edema Raloxifene 22.8315860553
MESH:D004487 Edema rosiglitazone 22.8312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 22.8312711302 11000095
MESH:D004487 Edema Tetradecanoylphorbol Acetate 22.8315177302 7812673 8273558 9599246 16716910 11698051 8113982
MESH:D004487 Edema Zymosan 22.837907874
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.6915322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.6918230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 19.0612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 19.0617692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 19.0615845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 19.0619031437
MESH:D016889 Endometrial Neoplasms Estradiol 11.0219148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Tamoxifen 11.0219155303 16202921 20544844 17893378
MESH:D016889 Endometrial Neoplasms Tretinoin 11.0216569247
MESH:D004715 Endometriosis Progesterone 7.8716134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.879294722 10568697
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.0912903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.0916530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.9311564622
MESH:D005124 Eye Abnormalities Tretinoin 7.9316938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 37.5915073043
MESH:D005234 Fatty Liver arsenite 37.5918296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 37.5915959796 61145 12631006 17595544 16239168 12795759 19224547 16045604
MESH:D005234 Fatty Liver Cyclosporine 37.5919224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 37.5915345470
MESH:D005234 Fatty Liver Raloxifene 37.5917473493
MESH:D005234 Fatty Liver rosiglitazone 37.5919196556
MESH:D005234 Fatty Liver Tamoxifen 37.5919224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0116709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1011858732
MESH:D005334 Fever Arachidonic Acid 4.3411852909
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1614745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.8119069698
MESH:D005355 Fibrosis arsenite 23.9218296743
MESH:D005355 Fibrosis Carbon Tetrachloride 23.9218705752
MESH:D005355 Fibrosis Cyclosporine 23.9212168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 23.9220067830
MESH:D005355 Fibrosis Tretinoin 23.9217994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.9116904648
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.3116452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.858708960
MESH:D005909 Glioblastoma Fenretinide 6.6416187019
MESH:D005909 Glioblastoma Tretinoin 6.6417312396
MESH:D005911 Gliosis Paraquat 4.7911124998
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2210696789
OMIM:233710 GRANULOMATOUS DISEASE, CHRONIC, AUTOSOMAL RECESSIVE, CYTOCHROME b-POSITIVE, TYPE II marker/mechanism
MESH:D006258 Head and Neck Neoplasms Tretinoin 2.9416096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.7816084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 9.9420471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.9410048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 9.9414991402 9664655
MESH:D006331 Heart Diseases Raloxifene 3.2811110106
MESH:D006402 Hematologic Diseases Benzene 4.3216183116
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0515720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0111000095
MESH:D006505 Hepatitis Carbon Tetrachloride 8.5019900420 19110552
MESH:D006505 Hepatitis Zymosan 8.5019110552
MESH:D006529 Hepatomegaly 2-xylene 7.827457028 7457013
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.8215340226 12621046 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.6615709030
MESH:D006689 Hodgkin Disease sodium arsenite 2.8512676792
MESH:D019584 Hot Flashes Estradiol 3.3817088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.678697196 16959395 15340226 16354765 18606429
MESH:D006930 Hyperalgesia rosiglitazone 7.1212083418
MESH:D006930 Hyperalgesia Tretinoin 7.1216870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1616899240
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2116778211
MESH:D006943 Hyperglycemia triphenyltin 5.3510522495
MESH:D006973 Hypertension Benzene 11.1617940673
MESH:D006973 Hypertension Cyclosporine 11.1610903974
MESH:D006973 Hypertension Raloxifene 11.1615787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 11.1618670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.7315338365
MESH:D006976 Hypertension, Pulmonary cyclo(Trp-Asp-Pro-Val-Leu) 4.9316327149
MESH:D015228 Hypertriglyceridemia triphenyltin 5.6410522495
MESH:D007021 Hypospadias Ethinyl Estradiol 3.4516569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.0415869954
MESH:D007246 Infertility triphenyltin 5.6715205045
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 9.8117937319
MESH:D007248 Infertility, Male Paraquat 9.814850670
MESH:D007248 Infertility, Male sodium arsenite 9.8112646999 15346721
MESH:D007249 Inflammation Arachidonic Acid 21.2215177302 9831321 17371808
MESH:D007249 Inflammation Progesterone 21.2215869954
MESH:D007249 Inflammation rosiglitazone 21.2212083418
MESH:D007249 Inflammation Tamoxifen 21.2219457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 21.2212878042 12200463
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 21.2211698051 8273558 15177302 7812673 7562506
MESH:D007249 Inflammation Zymosan 21.2211289658 8014878
MESH:D007333 Insulin Resistance bisphenol A 11.0716393666
MESH:D007333 Insulin Resistance Estradiol 11.0716393666 16627594
MESH:D007333 Insulin Resistance rosiglitazone 11.0716306350
MESH:D007410 Intestinal Diseases Tretinoin 3.4117994277
MESH:D043183 Irritable Bowel Syndrome Zymosan 5.4717553498
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.8416580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.8415992940 17551590
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0715604871
MESH:D007674 Kidney Diseases Acrolein 12.7212488133
MESH:D007674 Kidney Diseases Cyclosporine 12.728314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 12.7215618244
MESH:D007674 Kidney Diseases sodium arsenite 12.7220008137
MESH:D007680 Kidney Neoplasms Cyclosporine 10.6612371664
MESH:D007680 Kidney Neoplasms Estradiol 10.6615610895
MESH:D007680 Kidney Neoplasms Tamoxifen 10.6618625569
MESH:D007889 Leiomyoma Raloxifene 4.1616973256
MESH:D007938 Leukemia arsenic trioxide 9.4515070760
MESH:D007938 Leukemia Benzene 9.4518335105 17119257 14694614 15935818
MESH:D007938 Leukemia Tretinoin 9.4517143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.4712560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.9416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 14.1419077051
MESH:D007951 Leukemia, Myeloid Benzene 14.1417506065
MESH:D007951 Leukemia, Myeloid Tretinoin 14.1416932348 16482212 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.7316467208 19850784 20471514 16968895 17050201
MESH:D015470 Leukemia, Myeloid, Acute Benzene 5.7319478238
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 5.7319850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 6.8316966277 17712046 15748426 17107899 19225113 15213294 19035177 12712474 15336539 16112521 12018890 16891316 16331271 17869043 17217047 19075265 15622746 12679006 19642359 17649720 16330433 11468182 9834237 11161223 16823087
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 6.8315748426 9834237 16140955 19075265 17301526 17649720 17217047 17339181 17368321 19642359 16766008 16891316 16935935 19029980 16331271 17107899 12679006 19225113 17506722 16788101 17712046 17294898 17361223 16823087 19035177
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.0016882451
MESH:D007972 Leukoplakia, Oral Fenretinide 5.6716707609
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.059224671
MESH:D008064 Lipidoses Tamoxifen 2.8917567588 15342952
MESH:D008103 Liver Cirrhosis arsenite 6.1418296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.1416221502 11408273 17334410 17174718 17157831 16943688 11903743 21278145 16239168
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 8.0418395914 18251166 16027843 16248980 16192424 15370692 18205269 14512876 12741479 18472094 17631135 17823541 17525996 14748882 17640975 12666154 15996030 16136751 16116963 15730626 15052691 18376398 17766677 16015684 18481824 17714472 16097048 17976157 11481614 12445418 18418968 15673190 12586293 12649538 18412020 15959796 15362042 18277467 16033810 18472332 15893842 17481882 13678700 18054572 20821823 16638106 10355542 17922224 12667390 17761835 12958196 12389079 15818738 15338365 15650968 18210741 12632512 17698563 17944888 12632514 14724832 12609069 15057751 18395095 18156304 15925388 17721639 18420326 12546737 14620537 15123356 17869086 15876570 17805973 18429990 18006644 17565644 18263696 12898905 17708605 12445421 14716496 17900296 14716833 18339082 15931870 18279442 16011737 18166357 17557913 18317297 18187930 18705752
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 8.0414716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 8.0415980055 17347453
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 8.0418564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 8.0412878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 8.0418397230 16248980
MESH:D008107 Liver Diseases Carbon Tetrachloride 1.9916246199 15720792 17285989 15830285 16964402
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8015123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.3716899240 14706259
MESH:D008113 Liver Neoplasms Aflatoxin B1 19.612125692 18177683 9163691 15890375
MESH:D008113 Liver Neoplasms arsenic trioxide 19.6114682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 19.6120195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 19.6119294768
MESH:D008113 Liver Neoplasms sodium arsenite 19.6115276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 19.6116684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 19.6116984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 20.368603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 20.3620377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 20.3612562636
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 20.3612014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 20.3612151625
MESH:D008114 Liver Neoplasms, Experimental Trichloroethylene 20.367955063
MESH:D008133 Long QT Syndrome arsenic trioxide 3.0715213294
MESH:D008171 Lung Diseases Acrolein 7.0011504702
MESH:D008171 Lung Diseases sodium arsenite 7.0019095001
MESH:D017563 Lung Diseases, Interstitial Benzene 4.4314698565
MESH:D008175 Lung Neoplasms Aflatoxin B1 16.7814755239
MESH:D008175 Lung Neoplasms arsenic trioxide 16.7811798837 19825857
MESH:D008175 Lung Neoplasms arsenite 16.7816809336
MESH:D008175 Lung Neoplasms Benzene 16.7812562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 16.7817053015 18569708 20064080 18816296 6695378 20464547 18520028 20135361 20869020
MESH:D008175 Lung Neoplasms Methylene Chloride 16.7815172992
MESH:D008175 Lung Neoplasms sodium arsenite 16.7817306315 15276417 16712894 19931552 17077188
MESH:D008175 Lung Neoplasms Tamoxifen 16.7818625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 16.7819555203 11884234
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 16.7811807781
MESH:D008223 Lymphoma Benzene 3.4817584886 17119257
MESH:D015674 Mammary Neoplasms, Animal Benzene 8.8512562636
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 8.8519428831
MESH:D008325 Mammary Neoplasms, Experimental Benzene 24.8611921183
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 24.8611408345 11807958 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 24.8610697514
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 24.8617203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 24.8616827153
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 24.8614580682 19196722 11731420 19196723 16827153
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 24.868985016
MESH:D020149 Manganese Poisoning Estradiol 11.4019453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.4019453300
MESH:D008527 Medulloblastoma Tretinoin 2.6317453147
MESH:D008545 Melanoma Fenretinide 6.7116270382
MESH:D008545 Melanoma sodium arsenite 6.7116487513 19082730
MESH:D008545 Melanoma Tamoxifen 6.7119393235 12393984
MESH:D008545 Melanoma Tretinoin 6.7116752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.8115990972
MESH:D008546 Melanoma, Experimental Acrolein 4.8510803710
MESH:D008591 Meningomyelocele Tretinoin 4.0616940565
MESH:D008607 Mental Retardation Toluene 3.529294310
MESH:D024821 Metabolic Syndrome X rosiglitazone 4.0817261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4116801185
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.1815863610
MESH:D019957 Motor Skills Disorders Toluene 4.899294310
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 7.8516381670
MESH:D009062 Mouth Neoplasms Fenretinide 7.8516274795
MESH:D009101 Multiple Myeloma arsenic trioxide 10.7019549372 19417148 11468182 15949261 14977855
MESH:D009101 Multiple Myeloma Benzene 10.7017119195
MESH:D009101 Multiple Myeloma Raloxifene 10.7016497877
MESH:D009102 Multiple Organ Failure Zymosan 4.8712130978 15834315 15213630 10890648 10479408 12879239 18160304 15259001 15241586 17724436
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.3018349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.6816105982 16882451
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.6817596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.7312213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.0016810080
MESH:D009205 Myocarditis Particulate Matter 5.5912563109
MESH:D009232 Myxoma Raloxifene 5.1816343187
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.6116624393
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.4019393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3919410462
MESH:D009369 Neoplasms Acrolein 17.3617329238
MESH:D009369 Neoplasms Benzo(a)pyrene 17.3611141357
MESH:D009369 Neoplasms Fenretinide 17.3615958647 17353921
MESH:D009369 Neoplasms sodium arsenite 17.3611559025
MESH:D009369 Neoplasms Tretinoin 17.3616946489 16594593
MESH:D009369 Neoplasms Trichloroethylene 17.3611911487
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.3120056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.6319196722 19189210 19200415
MESH:D009389 Neovascularization, Pathologic arsenite 8.9315738583
MESH:D009389 Neovascularization, Pathologic Estradiol 8.9317289903
MESH:D009393 Nephritis Acrolein 5.9112653641
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.9818481113 19348381
MESH:D009410 Nerve Degeneration Paraquat 3.4416893418
MESH:D009421 Nervous System Malformations bisphenol A 20.5616427766 11399458
MESH:D009421 Nervous System Malformations Estradiol 20.5611399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 20.5614600291
MESH:D009421 Nervous System Malformations Tretinoin 20.569125849
MESH:D009436 Neural Tube Defects arsenic trioxide 15.3810525206
MESH:D009436 Neural Tube Defects Benzene 15.3815643154
MESH:D009436 Neural Tube Defects sodium arsenite 15.3812854658
MESH:D009436 Neural Tube Defects Tretinoin 15.389142499
MESH:D019636 Neurodegenerative Diseases Acrolein 4.2211342003
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 5.3116303764
MESH:D009784 Occupational Diseases Benzene 3.8615913788 17119257 15935809 15612468 15727169 17178637 16737584 15576619 17479406
MESH:D010024 Osteoporosis Raloxifene 3.1717882678 19059307 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 3.8915758505 15579764 17893378 17823083
MESH:D010049 Ovarian Diseases bisphenol A 4.6211985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 21.0019769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Benzene 21.0012562636
MESH:D010051 Ovarian Neoplasms Estradiol 21.0019401270
MESH:D010051 Ovarian Neoplasms Fenretinide 21.0016133793
MESH:D010051 Ovarian Neoplasms Progesterone 21.0017393432 16525653
MESH:D010051 Ovarian Neoplasms sodium arsenite 21.0017306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 21.0016936753
MESH:D010146 Pain Tretinoin 2.6216870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 11.2315580305
MESH:D010190 Pancreatic Neoplasms Fenretinide 11.2315580305
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 11.2315976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 11.2315976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3511578682
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 3.948330346 18922899 12065085 18404319
MESH:D010235 Paraganglioma arsenic trioxide 3.8219927285
MESH:D010300 Parkinson Disease Acrolein 5.3217690948
MESH:D010300 Parkinson Disease Paraquat 5.3215451049 16140633 12911755 16510128 11124998 11181820 11445065 15824117
MESH:D010302 Parkinson Disease, Secondary Paraquat 4.0716190885
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8712520081
MESH:D010538 Peritonitis Zymosan 4.5217826846 14761945 18977430 19088179 17371808 19641140 18557954 15979727 18760300 11985352 15259001
MESH:D010787 Photosensitivity Disorders Acrolein 5.3611550810
MESH:D011014 Pneumonia Paraquat 4.0912504350
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2118163543
MESH:D011230 Precancerous Conditions Cyclosporine 2.9212371664
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 8.2910548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.2911896295 11399792 11118676 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.4620887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.4620887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.3619131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.3617292933
MESH:D011471 Prostatic Neoplasms bisphenol A 2.3616740699
MESH:D011471 Prostatic Neoplasms Estradiol 2.3616740699
MESH:D011471 Prostatic Neoplasms Fenretinide 2.3617024972
MESH:D011471 Prostatic Neoplasms Raloxifene 2.3615731164 16536755 16220300
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.3616039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.3615067354
MESH:D011507 Proteinuria Tretinoin 3.2716636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.9515861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.1016882103
MESH:D011625 Pterygium Tretinoin 4.4216723453
MESH:D011629 Puberty, Precocious bisphenol A 4.4210548101
MESH:D011658 Pulmonary Fibrosis Paraquat 5.8317997886 16324872
MESH:D011658 Pulmonary Fibrosis Particulate Matter 5.8312475806
MESH:D011693 Purpura Raloxifene 5.1815770314
MESH:D051437 Renal Insufficiency Acrolein 4.6512732208
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 3.5711700416
MESH:D012135 Respiratory Sounds Paraquat 3.7011874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4918990726
MESH:D012162 Retinal Degeneration Fenretinide 8.3816303925
MESH:D012162 Retinal Degeneration Paraquat 8.3816458197
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.7616116481 16283617
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7218045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.6116646077
MESH:D012640 Seizures Toluene 3.486431079 9294310
MESH:D018805 Sepsis Zymosan 4.3511441115
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 20.1419755658 10029692
MESH:D012878 Skin Neoplasms Fenretinide 20.1416467112
MESH:D012878 Skin Neoplasms sodium arsenite 20.1418572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 20.1416192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 20.1418404319 8985016 8330346 11807781 12065085
MESH:D012878 Skin Neoplasms Tretinoin 20.1416467112
MESH:D013088 Spermatocele Ethinyl Estradiol 10.3116709447
MESH:D013088 Spermatocele Tamoxifen 10.3116709447
MESH:D013119 Spinal Cord Injuries Progesterone 9.6516503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 9.6519457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.5112854658
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.3917007042
MESH:D013274 Stomach Neoplasms Benzene 4.3912562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 4.392093021 20155912
MESH:D013274 Stomach Neoplasms Tretinoin 4.3917261132
MESH:D020521 Stroke Acrolein 8.1316269634
MESH:D020521 Stroke Raloxifene 8.1316837676
MESH:D019966 Substance-Related Disorders bisphenol A 3.6216045194 16684133
MESH:D013733 Testicular Diseases Toluene 4.5910514026 10048760
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8515669648
MESH:D013953 Thymus Neoplasms Benzene 4.5910850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5312697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 6.2919014326
MESH:D013964 Thyroid Neoplasms Tretinoin 6.2917045167 16026305
MESH:D013978 Tibial Fractures Estradiol 12.4619048282
MESH:D013978 Tibial Fractures Raloxifene 12.4619048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.4716051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.5915213294
MESH:D014376 Tuberculosis Tretinoin 3.0016040207
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 17.9012973940 12845720 20435036 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 17.9017053015
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 17.9016720286
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 17.9017572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 17.9017306315 16452187 16712894 11723127
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 17.9016712894 8653321 17572228
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 14.1116154183
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 14.1111813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 14.1116129372
MESH:D014591 Uterine Diseases bisphenol A 4.6314652134
MESH:D014594 Uterine Neoplasms Benzene 8.4112562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.4114692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.2416752155
MESH:D014605 Uveitis Cyclosporine 10.731336536
MESH:D014605 Uveitis Zymosan 10.7311006244
MESH:D014652 Vascular Diseases sodium arsenite 4.0617056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2212125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.8316837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2114671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.7116761959
MESH:D014846 Vulvar Neoplasms Raloxifene 5.1816343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8715886252
MESH:D009396 Wilms Tumor Tretinoin 3.6616287080
MESH:D014985 Xerophthalmia Cyclosporine 4.0717120751
Pathway ID Pathway Name
KEGG:05140 Leishmaniasis
KEGG:04670 Leukocyte transendothelial migration
KEGG:04380 Osteoclast differentiation
KEGG:04145 Phagosome
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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