AutismKB 2.0

Annotation Detail for ATP1A1


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Basic Information Top
Gene Symbol:ATP1A1 ( MGC3285,MGC51750 )
Gene Full Name: ATPase, Na+/K+ transporting, alpha 1 polypeptide
Band: 1p13.1
Quick LinksEntrez ID:476; OMIM: 182310; Uniprot ID:AT1A1_HUMAN; ENSEMBL ID: ENSG00000163399; HGNC ID: 799
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04973Carbohydrate digestion and absorption
hsa04970Salivary secretion
hsa04972Pancreatic secretion
hsa04974Protein digestion and absorption
hsa04960Aldosterone-regulated sodium reabsorption
hsa04964Proximal tubule bicarbonate reclamation
hsa04971Gastric acid secretion
hsa04260Cardiac muscle contraction
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1731Growth retardation
1781Rheumatoid arthritis
2091Hypertension
Desease Name
CARDIOVASCULAR
Na/K ATPase activity
hypertension
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of ATP1A1 mRNAaffects expression 17562736
C430898 AGN 194204 AGN 194204 results in increased expression of ATP1A1 mRNAincreases expression 16339527
D019386 Alendronate Alendronate affects the expression of ATP1A1 mRNAaffects expression 16079270
C010845 aluminum chloride aluminum chloride results in decreased activity of ATP1A1 proteindecreases activity 16162844
D000584 Amiloride Amiloride inhibits the reaction [AGT protein results in increased expression of ATP1A1 mRNA]decreases reaction|increases expression 14630723
D000638 Amiodarone Amiodarone results in decreased expression of ATP1A1 proteindecreases expression 8071999
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ATP1A1 mRNAaffects expression 16483693
C095105 bexarotene bexarotene results in increased expression of ATP1A1 mRNAincreases expression 16648578
D019256 Cadmium Chloride Cadmium Chloride results in decreased expression of ATP1A1 mRNAdecreases expression 12760830
D002118 Calcium [Calcium co-treated with Calcitriol] affects the expression of ATP1A1 mRNAaffects cotreatment|affects expression 15913539
D002713 Chlorine Chlorine results in decreased expression of ATP1A1 mRNAdecreases expression 18636392
D002713 Chlorine [Ozone co-treated with Chlorine] results in decreased expression of ATP1A1 mRNAaffects cotreatment|decreases expression 18636392
C007076 citral [Tretinoin co-treated with citral] results in increased expression of ATP1A1 mRNAaffects cotreatment|increases expression 16606641
D002995 Clofibric Acid Clofibric Acid affects the expression of ATP1A1 mRNAaffects expression 17602206
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATP1A1 mRNAaffects cotreatment|affects expression 17602206
D016572 Cyclosporine Cyclosporine results in decreased expression of ATP1A1 mRNAdecreases expression 20106945
D016190 Carboplatin Carboplatin results in decreased expression of ATP1A1 mRNAdecreases expression 18172885
D002945 Cisplatin Cisplatin results in decreased expression of ATP1A1 mRNAdecreases expression 18172885
D004041 Dietary Fats Dietary Fats results in increased expression of ATP1A1 mRNAincreases expression 18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATP1A1 mRNAaffects cotreatment|affects expression 17602206
D002117 Calcitriol [Calcium co-treated with Calcitriol] affects the expression of ATP1A1 mRNAaffects cotreatment|affects expression 15913539
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ATP1A1 mRNAaffects expression 16079270
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of ATP1A1 mRNAdecreases expression 17108234
D005047 Etoposide ATP1A1 protein affects the susceptibility to Etoposideaffects response to substance 16217747
C422415 farglitazar farglitazar results in increased expression of ATP1A1 mRNAincreases expression 15475592
C096856 FTI 277 FTI 277 inhibits the reaction [FGF10 protein results in increased expression of and results in increased activity of ATP1A1 protein]decreases reaction|increases activity|increases expression 12804770
C424943 glutamyl-Se-methylselenocysteine glutamyl-Se-methylselenocysteine results in decreased expression of ATP1A1 mRNAdecreases expression 11306469
D006220 Haloperidol Haloperidol results in decreased expression of ATP1A1 mRNAdecreases expression 15860345
D007657 Ketone Bodies Ketone Bodies results in decreased expression of ATP1A1 mRNAdecreases expression 15469884
C008281 limonene limonene results in increased expression of ATP1A1 mRNAincreases expression 12815608
D008094 Lithium Lithium inhibits the reaction [Ouabain results in increased expression of ATP1A1 mRNA]decreases reaction|increases expression 19995221
D008094 Lithium Lithium inhibits the reaction [Ouabain results in increased expression of ATP1A1 protein]decreases reaction|increases expression 19995221
D019808 Losartan Losartan inhibits the reaction [AGT protein results in increased expression of ATP1A1 mRNA]decreases reaction|increases expression 14630723
D017258 Medroxyprogesterone Acetate Medroxyprogesterone Acetate results in increased expression of ATP1A1 mRNAincreases expression 15866426
D008694 Methamphetamine Methamphetamine results in decreased expression of ATP1A1 mRNAdecreases expression 19149911
D015741 Metribolone Metribolone promotes the reaction [NDRG1 protein binds to ATP1A1 protein]affects binding|increases reaction 17220478
D016685 Mitomycin ATP1A1 protein affects the susceptibility to Mitomycinaffects response to substance 16217747
D010126 Ozone [Ozone co-treated with Chlorine] results in decreased expression of ATP1A1 mRNAaffects cotreatment|decreases expression 18636392
D010126 Ozone Ozone results in decreased expression of ATP1A1 mRNAdecreases expression 16330353
C041786 palm oil palm oil results in increased expression of ATP1A1 mRNAincreases expression 18042831
D010269 Paraquat Paraquat results in increased expression of ATP1A1 mRNAincreases expression 16854511
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ATP1A1 mRNAaffects binding|decreases expression|increases activity 19710929
D011374 Progesterone Progesterone results in increased expression of ATP1A1 mRNAincreases expression 18037150
D011433 Propranolol Propranolol inhibits the reaction [Terbutaline results in increased expression of ATP1A1 mRNA]decreases reaction|increases expression 9700104
D020849 Raloxifene Raloxifene affects the expression of ATP1A1 mRNAaffects expression 16079270
D012964 Sodium [Terbutaline results in increased expression of ATP1A1 protein] which results in increased transport of Sodiumincreases expression|increases transport 19880505
9700104
C016104 sodium bichromate sodium bichromate results in decreased expression of ATP1A1 mRNAdecreases expression 12760830
D010042 Ouabain Lithium inhibits the reaction [Ouabain results in increased expression of ATP1A1 mRNA]decreases reaction|increases expression 19995221
D010042 Ouabain Lithium inhibits the reaction [Ouabain results in increased expression of ATP1A1 protein]decreases reaction|increases expression 19995221
D010042 Ouabain Ouabain results in increased expression of ATP1A1 mRNAincreases expression 19995221
D010042 Ouabain Ouabain results in increased expression of ATP1A1 proteinincreases expression 19995221
D013726 Terbutaline Propranolol inhibits the reaction [Terbutaline results in increased expression of ATP1A1 mRNA]decreases reaction|increases expression 9700104
D013726 Terbutaline Terbutaline results in increased expression of ATP1A1 mRNAincreases expression 9700104
D013726 Terbutaline Terbutaline results in increased expression of ATP1A1 proteinincreases expression 19880505
9700104
D013726 Terbutaline [Terbutaline results in increased expression of ATP1A1 protein] which results in increased transport of Sodiumincreases expression|increases transport 9700104
19880505
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of ATP1A1 mRNAincreases expression 20055451
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of ATP1A1 mRNAdecreases expression 16054898
D014212 Tretinoin [Tretinoin co-treated with citral] results in increased expression of ATP1A1 mRNAaffects cotreatment|increases expression 16606641
C113580 U 0126 U 0126 inhibits the reaction [FGF10 protein results in increased expression of and results in increased activity of ATP1A1 protein]decreases reaction|increases activity|increases expression 12804770
C025643 vinclozolin vinclozolin affects the expression of ATP1A1 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Terbutaline 7.1614610225
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.1614514962 11752688 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.0518287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.4217505938
MESH:D000168 Acrocephalosyndactylia U 0126 4.9817694057
MESH:D058186 Acute Kidney Injury Cisplatin 3.5112690470 17670903 15814532
MESH:D055371 Acute Lung Injury Chlorine 7.6020601635
MESH:D055371 Acute Lung Injury pirinixic acid 7.6018653653
MESH:D000230 Adenocarcinoma Cisplatin 3.9511798837 17638652
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 3.9514692618
MESH:D000236 Adenoma Diethylnitrosamine 2.556695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 14.3416434500 19052882 18056438 19061943 17162532 17620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 14.3416434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 14.3416835633
MESH:D000382 Agricultural Workers' Diseases Paraquat 3.2711874814
MESH:D000419 Albuminuria Losartan 10.3312586211
MESH:D000419 Albuminuria Raloxifene 10.3317451421 17308373
MESH:D000505 Alopecia Tretinoin 3.2115955085
MESH:D000544 Alzheimer Disease Lithium 6.0019621015
MESH:D000544 Alzheimer Disease Ozone 6.0015513908
MESH:D000544 Alzheimer Disease Raloxifene 6.0015800139
MESH:D000686 Amyloidosis Terbutaline 5.147986221
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.5111748828
MESH:D000799 Angioedema Acetaminophen 3.3310982225
MESH:D001008 Anxiety Disorders vinclozolin 3.2419015723
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.3618057881 20041841 18218290
MESH:D001161 Arteriosclerosis Dietary Fats 8.2615238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.2611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.1115885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.1116412693
MESH:D001172 Arthritis, Rheumatoid Ozone 4.1815570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.1816292516
MESH:D001249 Asthma Ozone 4.3517854713 16373670
MESH:D001249 Asthma Tretinoin 4.3516456186
MESH:D050197 Atherosclerosis Losartan 4.1810821809
MESH:D001281 Atrial Fibrillation Amiodarone 3.5219698954 18651412
MESH:D001321 Autistic Disorder Acetaminophen 2.6218445737
MESH:D001321 Autistic Disorder Haloperidol 2.6219368416 18080171
MESH:D001321 Autistic Disorder Propranolol 2.6218766980
MESH:D001321 Autistic Disorder Terbutaline 2.6217400887 16417856
MESH:D001471 Barrett Esophagus Tretinoin 3.9216935849
MESH:D001714 Bipolar Disorder Lithium 4.0517594078 20046352 19153942 20338123
MESH:D001778 Blood Coagulation Disorders Amiodarone 18.2319483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 18.2319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 18.2312125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 18.2316206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.2715340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4315746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 10.5014601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 10.5014601052
MESH:D001919 Bradycardia Propranolol 5.066740701
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.8217868700
MESH:D001930 Brain Injuries Progesterone 9.3215845082 15380490 15665606
MESH:D001930 Brain Injuries Raloxifene 9.3216580743
MESH:D001943 Breast Neoplasms bexarotene 7.4816818667 16344269
MESH:D001943 Breast Neoplasms Calcitriol 7.4811237771
MESH:D001943 Breast Neoplasms Cisplatin 7.4819526202 18382427
MESH:D001943 Breast Neoplasms Dietary Fats 7.4820435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 7.4817474063
MESH:D001943 Breast Neoplasms Etoposide 7.4816322251
MESH:D001943 Breast Neoplasms glutamyl-Se-methylselenocysteine 7.4811306469
MESH:D001943 Breast Neoplasms Progesterone 7.4815562024 16175315 17614352
MESH:D001943 Breast Neoplasms Raloxifene 7.4817893378 17261762 15758505 17952589 16912660 17049068 17242785 15572757 17595753 17440819 15775269 16837676
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 7.4820435547
MESH:D001943 Breast Neoplasms Tretinoin 7.4816166294 16443354 16873071
MESH:D016535 Bronchial Hyperreactivity Ozone 3.2816777450 14754758 15516495 18315731 18417511 19059883 17626835
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.0816813970
MESH:D002100 Cachexia Ozone 4.2316183385
MESH:D019559 Capillary Leak Syndrome Terbutaline 5.349428835 11713377
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.4016835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.6416168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 5.743084413
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 5.7417982673
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 5.7420727157 20101231 18393292 19919837 17173139 16328049 16779866 18788625 18210153 17055752 19171122 10672840 19539802 19383236 11831363 20514400 17761372 17162532 20007298 18978308 20214788 16878318 16935385 19107877 19701751 19208518 3084413 16502159 16569478 18494052 21159647 20512989 17138121 16830150 19822196 16540662 17978847 20935162 19052882 18665156 16288022 20432363 18506893 17428255 10737359 16698587 20524982 18971187 19394651 19335982 3581430 20084675 18056438 19519916 18691550 16681979 19418558 16807293 18785209
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 5.741917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 8.0516247446
MESH:D002289 Carcinoma, Non-Small-Cell Lung Carboplatin 8.0516685392
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 8.0512023789 16685392
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 6.6211237771
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 6.6217066447 18337622 6189445
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 6.6216051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Amiloride 8.5714644129
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 8.5717572228
MESH:D006332 Cardiomegaly Losartan 6.2712586211 15969258
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.2718850075 18670907 16120746
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.7015710769 19225199
MESH:D002318 Cardiovascular Diseases Raloxifene 3.0915775269
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.5818974383
MESH:D002375 Catalepsy Haloperidol 4.4015215559 1977408
MESH:D002386 Cataract Acetaminophen 6.1810977129
MESH:D002386 Cataract Tretinoin 6.1817460283
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 5.4212371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 5.422727394 7505956 17174075 21159647
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.0816129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.9019052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.9016835633
MESH:D002779 Cholestasis Cyclosporine 11.1319486331
MESH:D002779 Cholestasis Ethinyl Estradiol 11.1317681005 16919318 16105132 11677210 15861022 17110522 17333356
MESH:D002779 Cholestasis pirinixic acid 11.1319176532
MESH:D002822 Choriocarcinoma Tretinoin 4.6416461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 4.9812621046 16354765 15668235 8697196 15340226
MESH:D002972 Cleft Palate Tretinoin 4.989407595
MESH:D003072 Cognition Disorders Raloxifene 4.1215800139
MESH:D003092 Colitis Amiloride 8.3412065299
MESH:D003092 Colitis Tretinoin 8.3417035595
MESH:D015179 Colorectal Neoplasms Cisplatin 2.3215273666
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.6314669216 17141729
MESH:D003371 Cough Terbutaline 5.0519679606
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.2610048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.2614991402 16925845 10589399 9211117 9664655 9142499 17551590 9224671 8800419 9125849
MESH:D003456 Cryptorchidism vinclozolin 3.8614966744
MESH:D007644 Darier Disease Lithium 5.4020338123
MESH:D016757 Death, Sudden, Cardiac Haloperidol 4.3720210726
MESH:D003704 Dementia Haloperidol 4.1311575062
MESH:D003865 Depressive Disorder, Major Raloxifene 3.7317474826
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1718249437
MESH:D018500 Diabetes Insipidus, Nephrogenic Lithium 5.2519244398
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 3.7220387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.7217107852
MESH:D003928 Diabetic Nephropathies Raloxifene 3.5115920148 17308373 17451421
MESH:D003929 Diabetic Neuropathies Progesterone 4.0017187935
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 7.482444490 18071297 11834606 11739529 19370779 18713872 12958197 12705907 12392966 10663392 16485898 11743745 10774834 11287661 19923254 10915739 14986274 19416960 15619225 16109766 12153990 11461765 19164858 15968718 19420014 19085960 11529661 16177239 16393943 19739265 17522070 16081117 12540782 16781746 16227642 14725611 14550746 17906064 17562736 12594235 11421492
MESH:D056486 Drug-Induced Liver Injury Amiodarone 7.4815265979 18218290
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 7.4819107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 7.4820420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.5819426721
MESH:D004362 Drug Toxicity Cisplatin 6.9119839026 12649298 12231392 15033597
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.9111462148
MESH:D050171 Dyslipidemias Dietary Fats 3.0818367378
MESH:D004417 Dyspnea Chlorine 4.1120016425
MESH:D004487 Edema pirinixic acid 8.8412083418
MESH:D004487 Edema Raloxifene 8.8415860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 8.8411000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.2218230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.2218230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 18.0015138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 18.0012538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 18.0017692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 18.0015845917
MESH:D016889 Endometrial Neoplasms Tretinoin 2.7716569247
MESH:D004715 Endometriosis Progesterone 7.4616134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.4610568697 9294722
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6016302075
MESH:D004938 Esophageal Neoplasms Cisplatin 2.6416785472 16481741 15173087 17638652 15464296
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.5611564622
MESH:D005124 Eye Abnormalities Tretinoin 7.5616938888 9664655
MESH:D005234 Fatty Liver Amiodarone 30.0214986274
MESH:D005234 Fatty Liver Cyclosporine 30.0219224547
MESH:D005234 Fatty Liver Dietary Fats 30.0217967931 19004024 19551842 18296743
MESH:D005234 Fatty Liver Diethylnitrosamine 30.0221071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 30.0215345470
MESH:D005234 Fatty Liver pirinixic acid 30.0220131406 19236843
MESH:D005234 Fatty Liver Raloxifene 30.0217473493
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.9611858732
MESH:D005355 Fibrosis Cyclosporine 22.5112639820 12168785
MESH:D005355 Fibrosis Dietary Fats 22.5118296743
MESH:D005355 Fibrosis Terbutaline 22.5115467267
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 22.5120067830
MESH:D005355 Fibrosis Tretinoin 22.5117994277
MESH:D005739 Gas Poisoning Chlorine 4.4920016425
MESH:D005756 Gastritis Acetaminophen 3.1616983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.4316973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.7816417039
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.718708960
MESH:D005909 Glioblastoma Tretinoin 2.6717312396
MESH:D005911 Gliosis Paraquat 4.6511124998
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.0810696789
MESH:D006130 Growth Disorders Amiloride 4.4219703807
MESH:D006258 Head and Neck Neoplasms Cisplatin 6.7415464296 15102660
MESH:D006258 Head and Neck Neoplasms Tretinoin 6.7416096774
MESH:D034381 Hearing Loss Cisplatin 3.8719898482
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.6416084493
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.0015464296
MESH:D006330 Heart Defects, Congenital Lithium 9.6319638421
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.6311294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 9.6314991402 9664655
MESH:D006331 Heart Diseases Raloxifene 3.1811110106
MESH:D006333 Heart Failure Losartan 10.2910979640
MESH:D006333 Heart Failure pirinixic acid 10.2920558911
MESH:D006333 Heart Failure Propranolol 10.2920082655
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9115720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.8811000095
MESH:D006529 Hepatomegaly Amiodarone 16.7015265979
MESH:D006529 Hepatomegaly pirinixic acid 16.7019176532 19772884 18467677 16221962
MESH:D006529 Hepatomegaly Propranolol 16.7016371745
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 16.7016120746 15340226 12621046
MESH:D006561 Herpes Simplex Etoposide 4.0610809021
MESH:D006689 Hodgkin Disease Cisplatin 6.4116200630 16170182
MESH:D006689 Hodgkin Disease Etoposide 6.4116200630 18180244 16135485 15147373 17606976
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.5316959395 15340226 16354765 8697196 18606429
MESH:D006930 Hyperalgesia Acetaminophen 10.8716870215
MESH:D006930 Hyperalgesia Alendronate 10.8716769263
MESH:D006930 Hyperalgesia Tretinoin 10.8716870215
MESH:D006937 Hypercholesterolemia Amiodarone 7.669751232 8137927
MESH:D006937 Hypercholesterolemia Dietary Fats 7.6621332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.0716778211
MESH:D006943 Hyperglycemia pirinixic acid 2.7420558911
MESH:D006948 Hyperkinesis Methamphetamine 5.0017658665
MESH:D006949 Hyperlipidemias Dietary Fats 3.1521332399
MESH:D006973 Hypertension Amiloride 17.7715174897 19344079 18524855
MESH:D006973 Hypertension Cyclosporine 17.7710903974
MESH:D006973 Hypertension Losartan 17.7710090350 12512695 12586211 15969258 14597852
MESH:D006973 Hypertension Ouabain 17.7718976649
MESH:D006973 Hypertension Raloxifene 17.7715787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 17.7718850075 18670907
MESH:D006985 Hyperventilation Terbutaline 5.5710895896
MESH:D007008 Hypokalemia Terbutaline 5.5817292646
MESH:D020514 Hypokalemic Periodic Paralysis Amiloride 5.3419822448
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3116945680 16569931
MESH:D007022 Hypotension Propranolol 4.716740701
MESH:D007037 Hypothyroidism Amiodarone 4.0217991464 18020914
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.9115869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.9912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 9.2217937319
MESH:D007248 Infertility, Male Paraquat 9.224850670
MESH:D007248 Infertility, Male vinclozolin 9.2216467254
MESH:D007249 Inflammation Amiloride 16.2817237260
MESH:D007249 Inflammation Dietary Fats 16.2820412841
MESH:D007249 Inflammation Diethylnitrosamine 16.2818785209
MESH:D007249 Inflammation Losartan 16.2812586211
MESH:D007249 Inflammation Progesterone 16.2815869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 16.2812200463 12878042
MESH:D007333 Insulin Resistance Dietary Fats 6.1011836018 18457598
MESH:D007333 Insulin Resistance pirinixic acid 6.1016306350
MESH:D007410 Intestinal Diseases Tretinoin 3.2717994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.4216580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.4215992940 17551590
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.9215604871
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.6215464296
MESH:D007674 Kidney Diseases Acetaminophen 11.9315629191 12587719
MESH:D007674 Kidney Diseases Cadmium Chloride 11.9316962696
MESH:D007674 Kidney Diseases Cisplatin 11.9319839026 15190930 12231392 18289764 12649298
MESH:D007674 Kidney Diseases Cyclosporine 11.938314463 18776723 10903974
MESH:D007680 Kidney Neoplasms Cyclosporine 2.3312371664
MESH:D007683 Kidney Tubular Necrosis, Acute Calcium 10.1616316344
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 10.1611231351
MESH:D007889 Leiomyoma Raloxifene 4.0316973256
MESH:D053609 Lethargy Terbutaline 5.8010895896
MESH:D007938 Leukemia Tretinoin 2.5017143497
MESH:D007948 Leukemia, Monocytic, Acute U 0126 4.8016972261
MESH:D007951 Leukemia, Myeloid Tretinoin 3.2519285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 1.9817596541 16294345 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.8116823087 12679006 17294898 16140955 16935935 17368321 17301526 9834237 19225113 16331271 16788101 17217047 17649720 16766008 19029980 17712046 17361223 17506722 16891316 15748426 19075265 19642359 19035177 17339181 17107899
MESH:D007984 Leydig Cell Tumor vinclozolin 4.2216417039
MESH:D056929 Liddle Syndrome Amiloride 5.4719344079
MESH:D017880 Limb Deformities, Congenital Tretinoin 2.949224671
MESH:D008064 Lipidoses Amiodarone 3.1417567588 15342952
MESH:D008103 Liver Cirrhosis Dietary Fats 5.6418296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 5.6418522880 20032147 19638242 18407596 18665156
MESH:D008106 Liver Cirrhosis, Experimental Losartan 4.3717900296 12445418 15573910
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.3715474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.3712878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.3716248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 5.7819784758 16611625 19460945 12969438 19014921 16610002 11587558 12587719
MESH:D008107 Liver Diseases Diethylnitrosamine 5.7817034775
MESH:D008107 Liver Diseases limonene 5.781715830
MESH:D017114 Liver Failure, Acute Acetaminophen 2.7917185352 16871587
MESH:D008113 Liver Neoplasms Clofibric Acid 11.9217602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 11.9218754104 20501860 21278145 19551842 19499222 21047994 12771043 19256749 19812893 19833225 19638242 9163691 19073162 2862719 15175105 19090486 18977376 18978307 12112319 20118626 16942905 20583210 19690152 10737359 18644402 20492335 20137499 20405173 19294768 21071580 20452335 19642983 19426721 2422723 19427195 19255062 21167192 19996281 19254457 20434301 19850985 20101389 18648771 15885732
MESH:D008113 Liver Neoplasms Mitomycin 11.9215113037
MESH:D008113 Liver Neoplasms pirinixic acid 11.9216377806 15890375 20007298
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 11.9216984957
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 4.6818164116 21159647 18775883 16842330 19126423 17854601 18253720 16267830 18079962 19539802 18544905 19009564 3124819 18308698 2563599 19519916 18093689 9362446 18282651 17174075 17942915 19004024
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 4.6812151625
MESH:D008133 Long QT Syndrome Amiodarone 3.1911989578 15350150 17391786
MESH:D008171 Lung Diseases Amiodarone 6.4212587719
MESH:D008171 Lung Diseases Ozone 6.4219066396 8266340
MESH:D017563 Lung Diseases, Interstitial Amiodarone 3.9618516814
MESH:D055370 Lung Injury Ozone 3.3620417186
MESH:D008175 Lung Neoplasms bexarotene 5.7617849452
MESH:D008175 Lung Neoplasms Cisplatin 5.7617225452 11798837 6189445
MESH:D008175 Lung Neoplasms Diethylnitrosamine 5.766695378 20970405 20512841 21163286
MESH:D008175 Lung Neoplasms Ozone 5.767614698 8597069
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 5.7611884234 19555203
MESH:D008223 Lymphoma Etoposide 3.5612854902 12556972
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.6511161223
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 5.2619196723 19196722 15591091
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 5.2617203775 11408345
MESH:D008382 Marfan Syndrome Losartan 5.5719430350
MESH:D008527 Medulloblastoma Tretinoin 2.5617453147
MESH:D008545 Melanoma Carboplatin 4.7111712820 16342250 16225601 12040289
MESH:D008545 Melanoma Cisplatin 4.7111135225 12393984 12883367 16809738 18176117 15577323 18332650 16432458 12374674 17023156 16248763 18505091 17761969
MESH:D008545 Melanoma Tretinoin 4.7116752155
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.2715990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.0719513568
MESH:D008591 Meningomyelocele Tretinoin 3.9316940565
MESH:D001523 Mental Disorders Haloperidol 3.5216856516
MESH:D008654 Mesothelioma Cisplatin 3.0217638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.2716801185
MESH:D008679 Metaplasia Ozone 4.5910496685
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.0415863610
MESH:D009101 Multiple Myeloma Raloxifene 3.0816497877
MESH:D009135 Muscular Diseases pirinixic acid 3.0116239165
MESH:D009181 Mycoses Amiodarone 4.3817974566 12754197
MESH:D009190 Myelodysplastic Syndromes Tretinoin 2.7717596541
MESH:D009203 Myocardial Infarction Lithium 8.4316288908
MESH:D009203 Myocardial Infarction Losartan 8.4312692751
MESH:D009203 Myocardial Infarction pirinixic acid 8.4319151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6112213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.5516411023
MESH:D009232 Myxoma Raloxifene 5.0416343187
MESH:D009361 Neoplasm Invasiveness Amiloride 4.8214644129
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.359029167 3581430
MESH:D009369 Neoplasms Carboplatin 9.7018854779 17925555
MESH:D009369 Neoplasms Cisplatin 9.7016773208
MESH:D009369 Neoplasms pirinixic acid 9.7017405874
MESH:D009369 Neoplasms Tretinoin 9.7016594593 16946489
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 4.2719196722
MESH:D009395 Nephritis, Interstitial Cisplatin 3.9815464296
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.9217954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.8619348381 18481113
MESH:D009410 Nerve Degeneration Paraquat 3.3216893418
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 7.9114600291
MESH:D009421 Nervous System Malformations Tretinoin 7.919125849
MESH:D009436 Neural Tube Defects Tretinoin 2.719142499
MESH:D009447 Neuroblastoma Cisplatin 3.178761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 6.8018514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 6.8020387270
MESH:D017599 Neuroectodermal Tumors Carboplatin 10.1112837982
MESH:D017599 Neuroectodermal Tumors Cisplatin 10.118761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6020387270
MESH:D009765 Obesity Dietary Fats 3.9317217161 21332399 20518802 18674790 20132043 19632207 11836018 16723640 18457598
MESH:D009765 Obesity pirinixic acid 3.9320558911
MESH:D007752 Obstetric Labor, Premature Terbutaline 5.5914998686
MESH:D010024 Osteoporosis Alendronate 10.2717882678
MESH:D010024 Osteoporosis Calcium 10.2717882678
MESH:D010024 Osteoporosis Raloxifene 10.2719059307 17882678 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 3.7617893378 15579764 17823083 15758505
MESH:D010051 Ovarian Neoplasms Cisplatin 13.0315464296 6897625 17225452 19769630
MESH:D010051 Ovarian Neoplasms Medroxyprogesterone Acetate 13.0317393432
MESH:D010051 Ovarian Neoplasms Progesterone 13.0317393432 16525653
MESH:D010051 Ovarian Neoplasms Tretinoin 13.0316936753
MESH:D010051 Ovarian Neoplasms U 0126 13.0316211241
MESH:D010146 Pain Acetaminophen 5.2416870215
MESH:D010146 Pain Tretinoin 5.2416870215
MESH:D010190 Pancreatic Neoplasms Cisplatin 14.1219003803
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 14.1216540662
MESH:D010190 Pancreatic Neoplasms Etoposide 14.1219003803
MESH:D010190 Pancreatic Neoplasms Mitomycin 14.1215113037
MESH:D010190 Pancreatic Neoplasms Tretinoin 14.1215976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2211578682
MESH:D010300 Parkinson Disease Paraquat 2.6111181820 16140633 11445065 15824117 12911755 15451049 11124998 16510128
MESH:D010302 Parkinson Disease, Secondary Paraquat 3.9416190885
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.7312520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.8315464296
MESH:D010538 Peritonitis Ozone 3.6416369182
MESH:D010997 Pleural Neoplasms Cisplatin 4.8217638057
MESH:D011014 Pneumonia Ozone 9.3818929643 18381685 18007984
MESH:D011014 Pneumonia Paraquat 9.3812504350
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.0818163543
MESH:D011230 Precancerous Conditions Cyclosporine 7.5212371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 7.522563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 7.8111118676 11222880 11399792 11896295
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 7.8118042343 19015723 18220299
MESH:D011469 Prostatic Diseases vinclozolin 4.4318220299
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.2715572423
MESH:D011471 Prostatic Neoplasms AGN 194204 2.3316000583
MESH:D011471 Prostatic Neoplasms Calcitriol 2.3318247401 16289102 15754350 16644109 12479363
MESH:D011471 Prostatic Neoplasms Etoposide 2.3317172428
MESH:D011471 Prostatic Neoplasms Raloxifene 2.3315731164 16220300 16536755
MESH:D011472 Prostatitis vinclozolin 4.4318629315
MESH:D011507 Proteinuria Tretinoin 3.1416636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.8115861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.0316882103
MESH:D011595 Psychomotor Agitation Haloperidol 4.4611575062
MESH:D011618 Psychotic Disorders Haloperidol 3.8811575062
MESH:D011625 Pterygium Tretinoin 4.2816723453
MESH:D011654 Pulmonary Edema Terbutaline 5.0010903255
MESH:D011658 Pulmonary Fibrosis Amiodarone 5.1112490602 12832656 11597910
MESH:D011658 Pulmonary Fibrosis Paraquat 5.1116324872 17997886
MESH:D011693 Purpura Raloxifene 5.0415770314
MESH:D051437 Renal Insufficiency Cisplatin 9.2115464296
MESH:D051437 Renal Insufficiency Losartan 9.2115728788
MESH:D015427 Reperfusion Injury pirinixic acid 2.1219058328
MESH:D012120 Respiration Disorders Chlorine 4.6918579056
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 8.0911700416
MESH:D012128 Respiratory Distress Syndrome, Adult Terbutaline 8.092878809
MESH:D012135 Respiratory Sounds Paraquat 3.5611874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.3518990726
MESH:D012162 Retinal Degeneration Paraquat 3.4816458197
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.6316116481 16283617
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.6618045962
MESH:D012512 Sarcoma, Ewing's Cisplatin 9.0214601052
MESH:D012512 Sarcoma, Ewing's Etoposide 9.0214601052
MESH:D012559 Schizophrenia Haloperidol 2.731830565 19369910 20107430 18513383
MESH:D012640 Seizures Lithium 3.6519660546
MESH:D012772 Shock, Septic Terbutaline 4.993431524
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.5818724381
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 4.6916192470
MESH:D012878 Skin Neoplasms Tretinoin 4.6916467112
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.8215464296
MESH:D013088 Spermatocele Ethinyl Estradiol 3.4216709447
MESH:D013119 Spinal Cord Injuries Progesterone 3.7715862959 16503802
MESH:D013226 Status Epilepticus Lithium 5.2719951488 19430551 19570321
MESH:D013274 Stomach Neoplasms Cisplatin 3.0917522103 15958060 18396642
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.0918456281
MESH:D013274 Stomach Neoplasms Tretinoin 3.0917261132
MESH:D013276 Stomach Ulcer Amiodarone 2.8818087811
MESH:D020521 Stroke Raloxifene 3.4216837676
MESH:D015173 Supratentorial Neoplasms Carboplatin 5.3012837982
MESH:D013610 Tachycardia Amiodarone 9.5311238279
MESH:D013610 Tachycardia Terbutaline 9.5310895896
MESH:D017180 Tachycardia, Ventricular Amiodarone 8.9319225199
MESH:D017180 Tachycardia, Ventricular Haloperidol 8.9320210726
MESH:D013736 Testicular Neoplasms Cisplatin 4.1615464296 17225452
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.1511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7315669648
MESH:D013959 Thyroid Diseases Amiodarone 10.3319731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 10.3312697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 5.887505956
MESH:D013964 Thyroid Neoplasms Tretinoin 5.8817045167 16026305
MESH:D013971 Thyrotoxicosis Amiodarone 4.3618020914 19584973
MESH:D013978 Tibial Fractures Raloxifene 4.6919048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.3516051514
MESH:D016171 Torsades de Pointes Amiodarone 3.6911989578 17467628
MESH:D014376 Tuberculosis Tretinoin 2.9016040207
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 4.7112973940 17225452 15464296
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 4.7117572228
MESH:D014581 Urticaria Acetaminophen 2.5110982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 8.1116803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.1116129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.8214692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.0916752155
MESH:D014605 Uveitis Cyclosporine 3.471336536
MESH:D014625 Vaginal Neoplasms Cisplatin 4.1115577323
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.0812125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.6916837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.0814671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.5716761959
MESH:D014839 Vomiting Cisplatin 4.2011897121
MESH:D014846 Vulvar Neoplasms Raloxifene 5.0416343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.7315886252
MESH:D015430 Weight Gain Dietary Fats 3.3116723640
MESH:D009396 Wilms Tumor Tretinoin 3.5416287080
MESH:D014985 Xerophthalmia Cyclosporine 3.9217120751
Pathway ID Pathway Name
KEGG:04960 Aldosterone-regulated sodium reabsorption
KEGG:04976 Bile secretion
KEGG:04973 Carbohydrate digestion and absorption
KEGG:04260 Cardiac muscle contraction
KEGG:04961 Endocrine and other factor-regulated calcium reabsorption
KEGG:04971 Gastric acid secretion
KEGG:04978 Mineral absorption
KEGG:04972 Pancreatic secretion
KEGG:04974 Protein digestion and absorption
KEGG:04964 Proximal tubule bicarbonate reclamation
KEGG:04970 Salivary secretion
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA62
    • No data
    Releated disease ID Related disease Name
    PA444552Hypertension
    Releated drug ID Related drug Name
    PA449319digoxin
    PA450218levonorgestrel
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00390 - Digoxin Enzyme Inhibitors;Antiarrhythmic Agents;Cardiotonic Agents;Anti-Arrhythmia Agents
    DB00511 antagonist Acetyldigitoxin Enzyme Inhibitors;Cardiotonic Agents;Anti-Arrhythmia Agents
    DB00774 other/unknown Hydroflumethiazide Antihypertensive Agents;Diuretics;Diuretics, Thiazide;Sodium Chloride Symporter Inhibitors
    DB00903 antagonist Ethacrynic acid Enzyme Inhibitors;Diuretics
    DB01021 antagonist Trichlormethiazide Antihypertensive Agents;Diuretics;Sodium Chloride Symporter Inhibitors
    DB01078 antagonist Deslanoside Enzyme Inhibitors;Cardiotonic Agents;Anti-Arrhythmia Agents
    DB01092 antagonist Ouabain Enzyme Inhibitors;Cardiotonic Agents
    DB01119 other Diazoxide Antihypertensive Agents;Vasodilator Agents;Diuretics, Thiazide
    DB01158 antagonist Bretylium Antihypertensive Agents;Anti-Arrhythmia Agents;Adrenergic Antagonists
    DB01244 antagonist Bepridil Antihypertensive Agents;Vasodilator Agents;Antiarrhythmic Agents;Calcium Channel Blockers;Anti-Arrhythmia Agents
    DB01345 - Potassium
    DB01370 binder Aluminium
    DB01378 - Magnesium
    DB01396 antagonist Digitoxin Enzyme Inhibitors;Antiarrhythmic Agents;Cardiotonic Agents;Anti-Arrhythmia Agents
    DB01430 binder Almitrine Respiratory System Agents
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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