AutismKB 2.0

Annotation Detail for NINJ1


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Basic Information Top
Gene Symbol:NINJ1 ( NIN1,NINJURIN )
Gene Full Name: ninjurin 1
Band: 9q22.31
Quick LinksEntrez ID:4814; OMIM: 602062; Uniprot ID:NINJ1_HUMAN; ENSEMBL ID: ENSG00000131669; HGNC ID: 7824
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C029728 4-phenylenediamine 4-phenylenediamine results in increased expression of NINJ1 mRNAincreases expression 16314067
D000643 Ammonium Chloride Ammonium Chloride affects the expression of NINJ1 mRNAaffects expression 16483693
D001205 Ascorbic Acid [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of NINJ1 mRNAaffects cotreatment|decreases expression 16443354
C002791 bismuth tripotassium dicitrate bismuth tripotassium dicitrate results in increased expression of NINJ1 mRNAincreases expression 15912405
C121718 dicyclanil dicyclanil results in increased expression of NINJ1 mRNAincreases expression 15664270
D004041 Dietary Fats Dietary Fats results in decreased expression of NINJ1 mRNAdecreases expression 18042831
D004052 Diethylnitrosamine [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of NINJ1 mRNAaffects cotreatment|increases expression 16158176
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of NINJ1 mRNAaffects cotreatment|increases expression 14656948
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of NINJ1 mRNAincreases expression 17005392
D002117 Calcitriol Calcitriol results in increased expression of NINJ1 mRNAincreases expression 12875902
D004137 Dinitrochlorobenzene Dinitrochlorobenzene results in increased expression of NINJ1 mRNAincreases expression 16314067
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NINJ1 mRNAaffects cotreatment|increases expression 17942748
D015073 2-Acetylaminofluorene [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of NINJ1 mRNAaffects cotreatment|increases expression 16158176
D015073 2-Acetylaminofluorene [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of NINJ1 mRNAaffects cotreatment|increases expression 14656948
D005472 Fluorouracil TP53 protein affects the reaction [Fluorouracil results in increased expression of NINJ1 mRNA]affects reaction|increases expression 15016801
D019833 Genistein Genistein results in increased expression of NINJ1 mRNAincreases expression 18847459
C029938 nickel sulfate nickel sulfate results in increased expression of NINJ1 mRNAincreases expression 16780908
16314067
D010126 Ozone Ozone results in decreased expression of NINJ1 mRNAdecreases expression 12763052
C041786 palm oil palm oil results in decreased expression of NINJ1 mRNAdecreases expression 18042831
D020849 Raloxifene [Raloxifene co-treated with ESR2 protein] results in decreased expression of NINJ1 mRNAaffects cotreatment|decreases expression 19059307
D012643 Selenium Selenium results in increased expression of NINJ1 mRNAincreases expression 19244175
D013629 Tamoxifen [Tamoxifen co-treated with ESR2 protein] results in decreased expression of NINJ1 mRNAaffects cotreatment|decreases expression 19059307
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NINJ1 mRNAaffects cotreatment|increases expression 17942748
D014212 Tretinoin [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of NINJ1 mRNAaffects cotreatment|decreases expression 16443354
D014212 Tretinoin Tretinoin results in increased expression of NINJ1 mRNAincreases expression 12875902
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.4214745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7215322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.4318287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8117505938
MESH:D055371 Acute Lung Injury nickel sulfate 4.1819131640 16100012 11954676 12718980
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.9214692618
MESH:D000230 Adenocarcinoma Fluorouracil 6.9217638652
MESH:D000230 Adenocarcinoma Genistein 6.9211473722
MESH:D000236 Adenoma 2-Acetylaminofluorene 6.7810737359
MESH:D000236 Adenoma Diethylnitrosamine 6.786695378 10737359
MESH:D002759 Adenoma, Bile Duct 2-Acetylaminofluorene 5.886705139
MESH:D018248 Adenoma, Liver Cell dicyclanil 16.7417162532
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.7419061943 17162532 17620307 18056438 19052882 16434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.7416835633
MESH:D000419 Albuminuria Raloxifene 4.4717308373 17451421
MESH:D000505 Alopecia Tretinoin 3.5115955085
MESH:D000544 Alzheimer Disease Ozone 4.2715513908
MESH:D000544 Alzheimer Disease Raloxifene 4.2715800139
MESH:D000686 Amyloidosis Diethylstilbestrol 4.3515469931
MESH:D000740 Anemia Fluorouracil 8.2916511603 15504547 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.2911748828
MESH:D001161 Arteriosclerosis Dietary Fats 9.4715238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.4711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.9415885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.9416412693
MESH:D001172 Arthritis, Rheumatoid Ozone 4.5615570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.5616292516
MESH:D001249 Asthma Ozone 4.8217854713 16373670
MESH:D001249 Asthma Tretinoin 4.8216456186
MESH:D001471 Barrett Esophagus Tretinoin 4.2716935849
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.5412125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 8.5416197459 16206674
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6815746008
MESH:D001930 Brain Injuries Raloxifene 4.3416580743
MESH:D001943 Breast Neoplasms Ascorbic Acid 8.1916443354
MESH:D001943 Breast Neoplasms Calcitriol 8.1911237771
MESH:D001943 Breast Neoplasms Dietary Fats 8.1920435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 8.1917474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 8.1917129689 15324884
MESH:D001943 Breast Neoplasms Fluorouracil 8.1918357371 16557594 19217205 18608205 16595493 16110121 15136595
MESH:D001943 Breast Neoplasms Genistein 8.1916873071 17200150 16541309
MESH:D001943 Breast Neoplasms Raloxifene 8.1915572757 16837676 17893378 15775269 17049068 17242785 15758505 16912660 17440819 17261762 17595753 17952589
MESH:D001943 Breast Neoplasms Tamoxifen 8.1920544844 19066611 19059307 18997820 15668708 18855134 19487384 11161223 15565566 20005174 17440819 18815881 19289846 18351453 19288272 19084267 21138602 20065188 16273361 19115204 18425577 18629630 19410462 19011961 16873071 19189212 17049068 19142967 19244106 17893378 20390343 18821012 20859285 16202921 19103187 16818667 21152245 17242785 17261762 19221464 19200415 20135344 19155303 19189210 18984771
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 8.1920435547
MESH:D001943 Breast Neoplasms Tretinoin 8.1916443354 16166294 16873071
MESH:D016535 Bronchial Hyperreactivity Ozone 3.5715516495 18315731 17626835 14754758 16777450 18417511 19059883
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.4616813970
MESH:D002100 Cachexia Ozone 4.6116183385
MESH:D002276 Carcinoid Tumor Fluorouracil 4.5416051944
MESH:D002277 Carcinoma Fluorouracil 7.8417121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.8416835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.3819066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.0316168501
MESH:D006528 Carcinoma, Hepatocellular 2-Acetylaminofluorene 16.5817761372 3084413 3581430 6705139 10737359
MESH:D006528 Carcinoma, Hepatocellular dicyclanil 16.5817162532
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 16.5816830150 19383236 18691550 20727157 19171122 16569478 20084675 18788625 17978847 19418558 16540662 20214788 20524982 18210153 20101231 19701751 19394651 20512989 21159647 19919837 19822196 3084413 18978308 18971187 18785209 18665156 18056438 10737359 18494052 19208518 16698587 20514400 20432363 18393292 17173139 19107877 17138121 16878318 17428255 16502159 17162532 10672840 3581430 17055752 19335982 16935385 19519916 16328049 18506893 19539802 16288022 19052882 20007298 11831363 16779866 20935162 17761372 16807293 16681979
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 16.5815948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 16.5817088986 17045692 18930000 17971768 16799960 16332177
MESH:D006528 Carcinoma, Hepatocellular Genistein 16.5816924424
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 16.5816924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 16.581917145
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.9618695887
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 7.3811237771
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 7.3816280240 18986760 16757204 17066447
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 7.3816096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 9.1117572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 9.1117572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3018670907 16120746 18850075
MESH:D002318 Cardiovascular Diseases Genistein 7.2016332659
MESH:D002318 Cardiovascular Diseases Raloxifene 7.2015775269
MESH:D002386 Cataract Tretinoin 3.0217460283
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 2.7717174075 21159647 2727394 7505956
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.4616129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.9519052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.9516835633
MESH:D002779 Cholestasis Ethinyl Estradiol 2.7811677210 16105132 17110522 16919318 17333356 15861022 17681005
MESH:D002822 Choriocarcinoma Tretinoin 5.0316461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.5816354765 15340226 12621046 15668235 8697196
MESH:D002972 Cleft Palate Tretinoin 5.589407595
MESH:D003072 Cognition Disorders Raloxifene 4.4915800139
MESH:D003092 Colitis Selenium 9.0617936198
MESH:D003092 Colitis Tretinoin 9.0617035595
MESH:D003093 Colitis, Ulcerative Dinitrochlorobenzene 3.8117373747 19159591
MESH:D003110 Colonic Neoplasms Fluorouracil 3.7717169374 15001691 16340194 18772588 17018589 17725105 17172411 16510598 17016597 17287894
MESH:D003110 Colonic Neoplasms Genistein 3.7717182828
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.0018383874 17594712 16331619 17016601 16282729 18448328 18802399 18288408 17695437 14970324 20501625 18949393 16524972 17255274 18509181 17094418 16303861 16391804 15289873 17454858 17401013 15148649
MESH:D003139 Common Cold Ascorbic Acid 5.3517323712
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9514669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4110048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.418800419 14991402 9142499 10589399 9211117 9125849 9224671 9664655 16925845 17551590
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.4316002989 12952375
MESH:D007644 Darier Disease Fluorouracil 4.6616733453
MESH:D003711 Demyelinating Diseases Tamoxifen 4.2319031437
MESH:D003865 Depressive Disorder, Major Raloxifene 4.0517474826
MESH:D017449 Dermatitis, Allergic Contact 4-phenylenediamine 11.2818759875 16533241 19470301 16823706 11906362 11298694
MESH:D017449 Dermatitis, Allergic Contact Dinitrochlorobenzene 11.2815491423
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 11.2816780908 16823706 11298694
MESH:D003877 Dermatitis, Contact 4-phenylenediamine 5.2111531941
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 10.0116506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 10.0120387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 10.0116647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 10.0117107852
MESH:D003928 Diabetic Nephropathies Raloxifene 8.6617451421 17308373 15920148
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.6619279558
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 5.9819107877
MESH:D056486 Drug-Induced Liver Injury Selenium 5.9815131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 5.9820420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6611462148
MESH:D050171 Dyslipidemias Dietary Fats 3.3618367378
MESH:C538011 Eales disease Ascorbic Acid 5.359068938
MESH:D004487 Edema Raloxifene 6.4615860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.4612711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.5118230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 11.5118230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 20.8915138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 20.8912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 20.8915845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 20.8919031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 11.4516402032
MESH:D004714 Endometrial Hyperplasia Genistein 11.4516402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 17.1015700306 16804899
MESH:D016889 Endometrial Neoplasms Genistein 17.1011473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 17.1016202921 19155303 17893378 20544844
MESH:D016889 Endometrial Neoplasms Tretinoin 17.1016569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.919294722 10568697
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9916302075
MESH:D004938 Esophageal Neoplasms Fluorouracil 2.4215173087 16785472 17638652 16481741 16337965
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.5111564622
MESH:D005124 Eye Abnormalities Tretinoin 8.5116938888 9664655
MESH:D005234 Fatty Liver Dietary Fats 23.3717967931 19551842 19004024 18296743
MESH:D005234 Fatty Liver Diethylnitrosamine 23.3721071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 23.3715345470
MESH:D005234 Fatty Liver Raloxifene 23.3717473493
MESH:D005234 Fatty Liver Tamoxifen 23.3719224547 14986274
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 7.9516002989 16513791 16534752 16611131 15751030
MESH:D052776 Female Urogenital Diseases Tamoxifen 7.9516709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3311858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4014745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.0519069698
MESH:D005355 Fibrosis Dietary Fats 14.0118296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 14.0120067830
MESH:D005355 Fibrosis Tretinoin 14.0117994277
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.8216452187
MESH:D005909 Glioblastoma Genistein 6.9316598420
MESH:D005909 Glioblastoma Tretinoin 6.9317312396
MESH:D005910 Glioma Fluorouracil 2.8216145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4710696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 7.5015162350 15102660 18337622
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.5016096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.0316084493
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 10.8416080930
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.8411294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 10.849664655 14991402
MESH:D006331 Heart Diseases Raloxifene 3.4411110106
MESH:D006333 Heart Failure Selenium 2.9917162251
MESH:D006390 Hemangioendothelioma 2-Acetylaminofluorene 5.196705139
MESH:D006394 Hemangiosarcoma 2-Acetylaminofluorene 4.296705139
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2111000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.7612621046 15340226 16120746
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 3.4316490937 16863852
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.928697196 16959395 15340226 16354765 18606429
MESH:D006930 Hyperalgesia Tretinoin 3.1116870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.4721332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.4416778211
MESH:D006949 Hyperlipidemias Dietary Fats 3.4921332399
MESH:D006965 Hyperplasia Diethylstilbestrol 4.3112960047 14722030
MESH:D006973 Hypertension Raloxifene 5.0617577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.0618670907 18850075
MESH:D007021 Hypospadias Diethylstilbestrol 10.8116002989
MESH:D007021 Hypospadias Ethinyl Estradiol 10.8116945680 16569931
MESH:D007246 Infertility Diethylstilbestrol 4.2315036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4017937319
MESH:D007249 Inflammation Dietary Fats 11.3820412841
MESH:D007249 Inflammation Diethylnitrosamine 11.3818785209
MESH:D007249 Inflammation Tamoxifen 11.3819457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.3812200463 12878042
MESH:D007251 Influenza, Human Selenium 4.0716624496
MESH:D007333 Insulin Resistance Dietary Fats 3.0218457598 11836018
MESH:D007410 Intestinal Diseases Tretinoin 3.6417994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.5316580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.5317551590 15992940
MESH:D007676 Kidney Failure, Chronic Selenium 3.7616518626
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 11.8915003126 14681315 16762066
MESH:D007680 Kidney Neoplasms Fluorouracil 11.8916985049
MESH:D007680 Kidney Neoplasms Tamoxifen 11.8918625569
MESH:D007859 Learning Disorders Diethylstilbestrol 3.9317184923
MESH:D007889 Leiomyoma Raloxifene 4.3716973256
MESH:D007938 Leukemia Genistein 6.2018980019 17468513
MESH:D007938 Leukemia Tretinoin 6.2017143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.5816482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0616294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.0717368321 17107899 17301526 9834237 19029980 19642359 17217047 19035177 17294898 16891316 19225113 16788101 17506722 19075265 16140955 17339181 17361223 17649720 16823087 17712046 16935935 12679006 16766008 16331271 15748426
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.219224671
MESH:D008064 Lipidoses Tamoxifen 3.0615342952 17567588
MESH:D008103 Liver Cirrhosis Dietary Fats 6.4018296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.4018407596 18522880 18665156 20032147 19638242
MESH:D008106 Liver Cirrhosis, Experimental Genistein 4.8317823541
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.8318564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.8312878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.8316248980 18397230
MESH:D008107 Liver Diseases Diethylnitrosamine 2.0717034775
MESH:D008113 Liver Neoplasms 2-Acetylaminofluorene 21.1614678523 16273603 11376686 18001218 10672840 10737359
MESH:D008113 Liver Neoplasms dicyclanil 21.1620118626
MESH:D008113 Liver Neoplasms Diethylnitrosamine 21.1618648771 20492335 2422723 19996281 20434301 20501860 19690152 21167192 18977376 19638242 19090486 12112319 15175105 19812893 19426721 21047994 19294768 18978307 19551842 19256749 19254457 19833225 18644402 19255062 19850985 10737359 18754104 12771043 20101389 15885732 20452335 20137499 20405173 19642983 21278145 19499222 16942905 19427195 9163691 2862719 19073162 20583210 21071580 20118626
MESH:D008113 Liver Neoplasms Diethylstilbestrol 21.1615890375 16712894
MESH:D008113 Liver Neoplasms Fluorouracil 21.1617045692 15113037 16603448 18383874
MESH:D008113 Liver Neoplasms Tamoxifen 21.1616684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 21.1616984957
MESH:D008114 Liver Neoplasms, Experimental 2-Acetylaminofluorene 13.526150874 1399818 534488
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 13.5218544905
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.5216267830 21159647 18775883 18093689 19539802 19004024 17174075 19126423 2563599 18079962 19009564 17942915 17854601 18253720 16842330 19519916 18308698 3124819 18164116 18282651 9362446 18544905
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.5212151625
MESH:D008171 Lung Diseases Ascorbic Acid 7.5116863852
MESH:D008171 Lung Diseases Ozone 7.5119066396 8266340
MESH:D055370 Lung Injury Ozone 3.7220417186
MESH:D008175 Lung Neoplasms 2-Acetylaminofluorene 10.4611376686
MESH:D008175 Lung Neoplasms Ascorbic Acid 10.4616401635
MESH:D008175 Lung Neoplasms Diethylnitrosamine 10.4620970405 20512841 21163286 6695378
MESH:D008175 Lung Neoplasms Fluorouracil 10.4615246190
MESH:D008175 Lung Neoplasms Ozone 10.467614698 8597069
MESH:D008175 Lung Neoplasms Tamoxifen 10.4618625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 10.4611884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.6615086387
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.0215166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.3815700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.3916002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.6319428831
MESH:D008325 Mammary Neoplasms, Experimental Genistein 9.5214578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Selenium 9.5215318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 9.5214580682 19196723 11731420 16827153 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.4219453300
MESH:D008527 Medulloblastoma Tretinoin 2.7317453147
MESH:D008545 Melanoma Dinitrochlorobenzene 5.1212202904 17334785
MESH:D008545 Melanoma Tamoxifen 5.1212393984 19393235
MESH:D008545 Melanoma Tretinoin 5.1216752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.0515990972
MESH:D008591 Meningomyelocele Tretinoin 4.2916940565
MESH:D008654 Mesothelioma Selenium 2.7415107826
MESH:D008679 Metaplasia Ozone 4.9810496685
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.4315863610
MESH:D009062 Mouth Neoplasms Fluorouracil 3.5318986760 16757204
MESH:D009101 Multiple Myeloma Raloxifene 3.3516497877
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.0117596541
MESH:D009203 Myocardial Infarction Genistein 2.8017141266
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9112213967
MESH:D015428 Myocardial Reperfusion Injury Genistein 3.5617141266
MESH:D009232 Myxoma Raloxifene 5.4316343187
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.563581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.5619393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4719410462
MESH:D009369 Neoplasms Diethylstilbestrol 7.9915313581
MESH:D009369 Neoplasms Fluorouracil 7.9918600527 16928823 18239605
MESH:D009369 Neoplasms Tretinoin 7.9916946489 16594593
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.8719200415 19196722 19189210
MESH:D009421 Nervous System Malformations Diethylstilbestrol 22.4111399458
MESH:D009421 Nervous System Malformations Genistein 22.4116427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 22.4114600291
MESH:D009421 Nervous System Malformations Tretinoin 22.419125849
MESH:D009436 Neural Tube Defects Tretinoin 2.979142499
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.2320387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9920387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.3516436463
MESH:D009765 Obesity Ascorbic Acid 4.8117217161
MESH:D009765 Obesity Dietary Fats 4.8116723640 20518802 17217161 20132043 18457598 19632207 11836018 18674790 21332399
MESH:D010024 Osteoporosis Genistein 7.0719401787
MESH:D010024 Osteoporosis Raloxifene 7.0717882678 15775268 19059307
MESH:D015663 Osteoporosis, Postmenopausal Genistein 9.7316169203
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 9.7317823083 15579764 15758505 17893378
MESH:D010051 Ovarian Neoplasms Genistein 4.8119005980
MESH:D010051 Ovarian Neoplasms Tretinoin 4.8116936753
MESH:D010146 Pain Tretinoin 2.8016870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.3616540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 8.3615113037 16929163 19003803 16500647
MESH:D010190 Pancreatic Neoplasms Tretinoin 8.3615976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5611578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1212520081
MESH:D010538 Peritonitis Ozone 4.0016369182
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.0414722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.5416977796 15687265
MESH:D010954 Plasmacytoma Selenium 4.7615087411
MESH:D011014 Pneumonia Ozone 4.2618929643 18007984 18381685
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4318163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.442563599
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 9.1317184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.1311896295 11222880 11399792 11118676
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.6515572423
MESH:D011471 Prostatic Neoplasms Calcitriol 1.8915754350 16289102 12479363 18247401 16644109
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 1.8915046698 15846301 17136230
MESH:D011471 Prostatic Neoplasms Fluorouracil 1.8918626508 19082440
MESH:D011471 Prostatic Neoplasms Genistein 1.8916925846 15256057 15378649
MESH:D011471 Prostatic Neoplasms Raloxifene 1.8915731164 16220300 16536755
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8915067354
MESH:D011507 Proteinuria Tretinoin 3.4816636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.1816919318 15861022
MESH:D011625 Pterygium Tretinoin 4.6616723453
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 5.2014606601
MESH:D011693 Purpura Raloxifene 5.4315770314
MESH:D012004 Rectal Neoplasms Fluorouracil 3.9015538739 18286688 18722050 16160472
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7118990726
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 3.2716849425
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.9816116481 16283617
MESH:D012871 Skin Diseases Ascorbic Acid 3.1818709164
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.3616192470
MESH:D012878 Skin Neoplasms Tretinoin 5.3616467112
MESH:D013088 Spermatocele Diethylstilbestrol 19.3916002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 19.3916709447
MESH:D013088 Spermatocele Tamoxifen 19.3916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.9119457130
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.3218456281
MESH:D013274 Stomach Neoplasms Fluorouracil 3.3215786421 18396642 16951190 17522103 19015929 17498489 19084572 16424979 18567086 17172411
MESH:D013274 Stomach Neoplasms Tretinoin 3.3217261132
MESH:D013276 Stomach Ulcer Ascorbic Acid 3.7718726076
MESH:D020521 Stroke Ascorbic Acid 8.6516517955 16403987
MESH:D020521 Stroke Raloxifene 8.6516837676
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0415669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7712697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.847505956
MESH:D013964 Thyroid Neoplasms Tretinoin 6.8417045167 16026305
MESH:D013978 Tibial Fractures Raloxifene 5.0819048282
MESH:D014062 Tongue Neoplasms Fluorouracil 9.4416280240
MESH:D014062 Tongue Neoplasms Tretinoin 9.4416051514
MESH:D014376 Tuberculosis Tretinoin 3.1516040207
MESH:D001749 Urinary Bladder Neoplasms 2-Acetylaminofluorene 11.5915289314 15867355 1399818
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 11.5917306315 16452187 16712894
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 11.5917572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 11.5916712894 8653321 17572228
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 15.2216175088
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 15.2216803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 15.2216129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.0414652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 9.0515809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.0514692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.4816752155
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.3116513791 16002989
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4712125929
MESH:D054556 Venous Thromboembolism Raloxifene 5.0816837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4214671159 15869587
MESH:D014820 Vitiligo Tretinoin 3.9316761959
MESH:D014846 Vulvar Neoplasms Raloxifene 5.4316343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1215886252
MESH:D015430 Weight Gain Dietary Fats 3.6216723640
MESH:D009396 Wilms Tumor Tretinoin 3.8516287080
No data
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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