AutismKB 2.0

Annotation Detail for NKG7


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Basic Information Top
Gene Symbol:NKG7 ( GIG1,GMP-17,p15-TIA-1 )
Gene Full Name: natural killer cell group 7 sequence
Band: 19q13.41
Quick LinksEntrez ID:4818; OMIM: 606008; Uniprot ID:NKG7_HUMAN; ENSEMBL ID: ENSG00000105374; HGNC ID: 7830
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of NKG7 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of NKG7 mRNAaffects expression 16483693
D005419 Flavonoids Flavonoids results in increased expression of NKG7 mRNAincreases expression 18035473
C006253 pirinixic acid pirinixic acid results in decreased expression of NKG7 mRNAdecreases expression 17426115
D011374 Progesterone Progesterone results in increased expression of NKG7 mRNAincreases expression 18070364
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1018287403
MESH:D055371 Acute Lung Injury pirinixic acid 3.5218653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.0216434500
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.5219483382
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.9517868700
MESH:D001930 Brain Injuries Progesterone 4.7415665606 15380490 15845082
MESH:D001943 Breast Neoplasms Progesterone 2.4116175315 15562024 17614352
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.403084413
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002779 Cholestasis pirinixic acid 3.0819176532
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5618249437
MESH:D003929 Diabetic Neuropathies Progesterone 4.9817187935
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6612705907 11739529 11834606 12153990 15968718 11743745 11287661 12540782 19739265 18713872 19420014 17562736 14986274 14550746 12392966 19370779 16109766 19164858 15619225 10774834 10915739 16485898 16081117 10663392 17522070 19416960 12958197 12594235 17906064 16393943 14725611 2444490 19085960 11461765 16227642 18071297 11421492 11529661 16781746 19923254 16177239
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004487 Edema pirinixic acid 2.8512083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 4.2217692515
MESH:D004715 Endometriosis Progesterone 4.1116134523
MESH:D005234 Fatty Liver pirinixic acid 3.1419236843 20131406
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D006333 Heart Failure pirinixic acid 2.7320558911
MESH:D006529 Hepatomegaly pirinixic acid 3.4819176532 18467677 19772884 16221962
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D006943 Hyperglycemia pirinixic acid 3.5320558911
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.8915869954
MESH:D007249 Inflammation Flavonoids 5.8117296493
MESH:D007249 Inflammation Progesterone 5.8115869954
MESH:D007333 Insulin Resistance pirinixic acid 2.8516306350
MESH:D007674 Kidney Diseases Acetaminophen 2.3815629191 12587719
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008107 Liver Diseases Acetaminophen 1.6916611625 19460945 11587558 12969438 19014921 19784758 12587719 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5817185352 16871587
MESH:D008113 Liver Neoplasms pirinixic acid 1.9216377806 20007298 15890375
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 3.0717203775 11408345
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D009135 Muscular Diseases pirinixic acid 3.9916239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2619151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2216411023
MESH:D009369 Neoplasms pirinixic acid 2.0917405874
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D009765 Obesity pirinixic acid 1.8820558911
MESH:D010051 Ovarian Neoplasms Progesterone 2.6116525653 17393432
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D015427 Reperfusion Injury pirinixic acid 2.5319058328
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.9518045962
MESH:D013119 Spinal Cord Injuries Progesterone 4.8216503802 15862959
MESH:D014581 Urticaria Acetaminophen 3.3810982225
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA31639
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA450379mercaptopurine
    PA450428methotrexate
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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