Annotation Detail for NPHP1
Basic Information Top
| Gene Symbol: | NPHP1 ( FLJ97602,JBTS4,NPH1,SLSN1 ) |
|---|---|
| Gene Full Name: | nephronophthisis 1 (juvenile) |
| Band: | 2q13 |
| Quick Links | Entrez ID:4867; OMIM: 607100; Uniprot ID:NPHP1_HUMAN; ENSEMBL ID: ENSG00000144061; HGNC ID: 7905 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| No data |
| No data |
| Desease Name |
|---|
| Joubert syndrome |
| Joubert syndrome nephronophthisis |
| NEUROLOGICAL |
| No data |
| Desease Name |
|---|
| Joubert syndrome 4 |
| Senior-Loken syndrome-1 |
| Nephronophthisis 1, juvenile |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of NPHP1 mRNA | affects expression | 17562736 |
| D043343 | Testosterone Propionate | Testosterone Propionate results in decreased expression of NPHP1 mRNA | decreases expression | 15601916 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.91 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.83 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 11834606 16177239 11287661 12392966 16227642 19420014 14725611 16109766 16781746 16081117 11461765 19164858 18071297 18713872 19416960 16393943 12153990 11739529 12540782 15619225 14550746 11743745 14986274 19085960 15968718 12958197 17522070 11529661 11421492 10663392 12705907 2444490 19739265 16485898 17906064 10774834 10915739 19923254 17562736 19370779 12594235 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 5.17 | 19426721 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.74 | 16983495 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.11 | 16870215 | |
| MESH:C536296 | Joubert syndrome 4 | marker/mechanism | |||
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.44 | 12587719 15629191 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 16610002 19014921 16611625 19784758 11587558 12969438 12587719 19460945 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.74 | 17185352 16871587 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.33 | 19513568 | |
| OMIM:256100 | NEPHRONOPHTHISIS 1 | marker/mechanism | |||
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.31 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.82 | 16870215 | |
| OMIM:266900 | SENIOR-LOKEN SYNDROME 1 | marker/mechanism | |||
| MESH:D014581 | Urticaria | Acetaminophen | 3.58 | 10982225 |
| No data |