AutismKB 2.0

Annotation Detail for NRAP


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Basic Information Top
Gene Symbol:NRAP ( - )
Gene Full Name: nebulin-related anchoring protein
Band: 10q25.3
Quick LinksEntrez ID:4892; OMIM: 602873; Uniprot ID:NRAP_HUMAN; ENSEMBL ID: ENSG00000197893; HGNC ID: 7988
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
CHEMDEPENDENCY
smoking cessation
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D002857 Chromium LEPR gene mutant form promotes the reaction [[Niacin binds to Chromium] which results in increased expression of NRAP mRNA]affects binding|increases expression|increases reaction 16940432
D004041 Dietary Fats Dietary Fats results in increased expression of NRAP mRNAincreases expression 18042831
D009525 Niacin LEPR gene mutant form promotes the reaction [[Niacin binds to Chromium] which results in increased expression of NRAP mRNA]affects binding|increases expression|increases reaction 16940432
C041786 palm oil palm oil results in increased expression of NRAP mRNAincreases expression 18042831
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D001161 Arteriosclerosis Dietary Fats 4.4515238619
MESH:D001943 Breast Neoplasms Chromium 2.6015986119
MESH:D001943 Breast Neoplasms Dietary Fats 2.6020435547
MESH:D050171 Dyslipidemias Dietary Fats 3.7318367378
MESH:D005234 Fatty Liver Dietary Fats 3.6618296743 17967931 19004024 19551842
MESH:D005355 Fibrosis Dietary Fats 4.0818296743
MESH:D006937 Hypercholesterolemia Dietary Fats 4.0221332399
MESH:D006949 Hyperlipidemias Dietary Fats 4.0821332399
MESH:D007249 Inflammation Dietary Fats 2.6020412841
MESH:D007333 Insulin Resistance Dietary Fats 3.3418457598 11836018
MESH:D007674 Kidney Diseases Chromium 4.1117934191
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0718296743
MESH:D009765 Obesity Dietary Fats 2.3617217161 18674790 21332399 18457598 11836018 20132043 19632207 20518802 16723640
MESH:D015430 Weight Gain Dietary Fats 4.1116723640
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018