AutismKB 2.0

Annotation Detail for NRGN


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Basic Information Top
Gene Symbol:NRGN ( RC3,hng )
Gene Full Name: neurogranin (protein kinase C substrate, RC3)
Band: 11q24.2
Quick LinksEntrez ID:4900; OMIM: 602350; Uniprot ID:NEUG_HUMAN; ENSEMBL ID: ENSG00000154146; HGNC ID: 8000
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
PSYCH
schizophrenia
Desease Name
Schizophrenia
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of NRGN mRNAincreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of NRGN mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of NRGN mRNAaffects expression 16483693
C006780 bisphenol A bisphenol A results in decreased expression of NRGN mRNAdecreases expression 12075121
C006780 bisphenol A bisphenol A results in increased expression of NRGN mRNAincreases expression 15498886
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of NRGN mRNAdecreases expression 12075121
D005419 Flavonoids Flavonoids results in decreased expression of NRGN mRNAdecreases expression 18035473
D019833 Genistein Genistein results in decreased expression of NRGN mRNAdecreases expression 12075121
D007657 Ketone Bodies Ketone Bodies results in increased expression of NRGN mRNAincreases expression 16807920
D010416 Pentachlorophenol Pentachlorophenol results in increased expression of NRGN mRNAincreases expression 19082768
C017947 sodium arsenite sodium arsenite results in decreased expression of NRGN mRNAdecreases expression 12760830
D014284 Triiodothyronine Triiodothyronine results in increased expression of NRGN mRNAincreases expression 15708448
D014284 Triiodothyronine Triiodothyronine results in increased expression of NRGN proteinincreases expression 15708448
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of NRGN mRNAdecreases expression 11007951
D014212 Tretinoin Tretinoin results in decreased expression of NRGN mRNAdecreases expression 16249480
D014635 Valproic Acid Valproic Acid results in increased expression of NRGN mRNAincreases expression 19101580
D014801 Vitamin A Vitamin A affects the expression of NRGN mRNAaffects expression 14529804
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.4811752688 14514962 15322242
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 8.488875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 10.4719490988
MESH:D000015 Abnormalities, Multiple Vitamin A 10.4710992263
MESH:D000138 Acidosis Ammonium Chloride 3.6118287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0017505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.3814692618
MESH:D000230 Adenocarcinoma Genistein 4.3811473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.773712494
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.4316835633
MESH:D000310 Adrenal Gland Neoplasms Pentachlorophenol 13.5110696769
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 13.5115276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.9617306315 16712894
MESH:D000505 Alopecia Tretinoin 3.6415955085
MESH:D000550 Amblyopia Valproic Acid 5.3017688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 9.0711748828
MESH:D000740 Anemia Vitamin A 9.0716960172
MESH:D018798 Anemia, Iron-Deficiency Vitamin A 4.8216960172
MESH:D000799 Angioedema Acetaminophen 3.9110982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.5917497229
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.2615885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.2616412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2716292516
MESH:D001249 Asthma Tretinoin 5.2416456186
MESH:D001249 Asthma Vitamin A 5.2416732791
MESH:D001321 Autistic Disorder Acetaminophen 1.8518445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8517507914 18177632 18558336 16609825 18985861 15238991 18316065 18775368 17157402 17688650 19232924 19460635 20603192 18940202 18396377
MESH:D001471 Barrett Esophagus Tretinoin 4.4416935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.0811289319 1440618
MESH:D001714 Bipolar Disorder Valproic Acid 3.0917594078 20046352
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.0312125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 9.0316206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 8.0815746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 8.088888407
MESH:D001862 Bone Resorption bisphenol A 3.8911985600
MESH:D001943 Breast Neoplasms bisphenol A 1.9617123778
MESH:D001943 Breast Neoplasms Genistein 1.9617200150 16541309 16873071
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9620435547
MESH:D001943 Breast Neoplasms Tretinoin 1.9616873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 13.1916813970
MESH:D001997 Bronchopulmonary Dysplasia Vitamin A 13.1917377406 17426644
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8216835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2216168501
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 8.923581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.923084413
MESH:D006528 Carcinoma, Hepatocellular Genistein 8.9216924424
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 8.9216507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 8.921917145
MESH:D002278 Carcinoma in Situ bisphenol A 5.0417123778
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.697296757
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.7118572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.7116096774 16051514
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3818670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Genistein 3.3216332659
MESH:D002386 Cataract Acetaminophen 7.2810977129
MESH:D002386 Cataract Tretinoin 7.2817460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 6.807505956
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 6.8020056578 19524636
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.6416129372
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.7220734317
MESH:D015362 Child Nutrition Disorders Vitamin A 5.5416153327
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1916835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.7019486331 9022650
MESH:D002779 Cholestasis Ethinyl Estradiol 13.7011677210 17681005 15861022 17333356 17110522 16919318 16105132
MESH:D002779 Cholestasis Vitamin A 13.7016175620
MESH:D002822 Choriocarcinoma Tretinoin 5.2216461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 9.9815340226 15668235 8697196 16354765 12621046
MESH:D002972 Cleft Palate Tretinoin 9.989407595
MESH:D002972 Cleft Palate Vitamin A 9.9816054864
MESH:D003092 Colitis Tretinoin 3.7517035595
MESH:D003110 Colonic Neoplasms Genistein 4.1617182828
MESH:D003110 Colonic Neoplasms Vitamin A 4.1616267017 17219422
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0817141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 5.4720055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 5.479125849 17551590 9224671 16925845 9142499 10589399 14991402 8800419 9211117 9664655
MESH:D019465 Craniofacial Abnormalities Valproic Acid 5.4716575769 8888407 17688650
MESH:D019465 Craniofacial Abnormalities Vitamin A 5.4710992263
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.8411906362 2524372 12868966 18759878 8156756 14531868 8970840 11298694
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.523621924 2952479
MESH:D003922 Diabetes Mellitus, Type 1 Vitamin A 3.5116506275
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 4.3516647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.3517107852
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 9.0211289319 6679447 16192314 18692083 18289764 1440618 9328219 6482804 9022650 9653073 8291058 18648102 7440962
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.0217906064 15968718 12540782 11461765 19420014 19739265 18713872 11421492 12594235 16393943 12153990 19923254 11739529 16485898 11743745 16781746 14550746 18071297 10663392 2444490 10774834 11834606 19164858 19085960 15619225 16177239 11529661 10915739 12392966 19416960 17522070 16109766 16227642 14725611 14986274 11287661 17562736 19370779 12705907 16081117 12958197
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 9.0220420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 9.021733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1619426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7811462148
MESH:D015352 Dry Eye Syndromes Vitamin A 5.8516146918
MESH:D004421 Dystonia Valproic Acid 4.081851702
MESH:C538011 Eales disease Vitamin A 5.689068938
MESH:D004480 Ectromelia Vitamin A 5.8816054864
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.4111000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 12.1618230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 12.1618230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.2212538720
MESH:D004714 Endometrial Hyperplasia Genistein 4.6416402032
MESH:D016889 Endometrial Neoplasms Genistein 7.6111473722
MESH:D016889 Endometrial Neoplasms Tretinoin 7.6116569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.0510568697 9294722
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.193659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 3.9816628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.9520417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.616254150 7562514 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.347750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.113659116
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.113581430
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.9011564622
MESH:D005124 Eye Abnormalities Tretinoin 8.9016938888 9664655
MESH:D005234 Fatty Liver Ethinyl Estradiol 7.8415345470
MESH:D005234 Fatty Liver Valproic Acid 7.8414986274 19224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5011858732
MESH:D005315 Fetal Diseases Valproic Acid 4.9516575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.1718558336 8888407
MESH:D005327 Fetal Resorption Vitamin A 5.4316054864
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.086705139
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.7620067830
MESH:D005355 Fibrosis Tretinoin 8.7617994277
MESH:D005756 Gastritis Acetaminophen 3.7416983495
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.7316452187
MESH:D005909 Glioblastoma Genistein 7.2716598420
MESH:D005909 Glioblastoma Tretinoin 7.2717312396
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.077505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6610696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.2016096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2216084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.3411294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 11.3414991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin A 11.3410992263 16080930
MESH:D006394 Hemangiosarcoma Pentachlorophenol 5.0815200160
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3611000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.556705139
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.9312621046 15340226 16120746
MESH:D006548 Hernia, Diaphragmatic Vitamin A 3.6317436238 16877224 16490937 16863852 16292552 15707848
MESH:D015658 HIV Infections Vitamin A 3.8316960176
MESH:D006679 HIV Seropositivity Vitamin A 5.6517209195
MESH:D006689 Hodgkin Disease sodium arsenite 3.1812676792
MESH:D006849 Hydrocephalus Valproic Acid 4.9217688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.118697196 16354765 16959395 18606429 15340226
MESH:D006930 Hyperalgesia Acetaminophen 7.7016870215
MESH:D006930 Hyperalgesia Tretinoin 7.7016870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6116778211
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.9815034207
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9118850075 18670907
MESH:D006986 Hypervitaminosis A Vitamin A 6.2316054864
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8516945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.7017937319
MESH:D007248 Infertility, Male sodium arsenite 6.7012646999 15346721
MESH:D007249 Inflammation Flavonoids 5.0417296493
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 5.0412878042 12200463
MESH:D007333 Insulin Resistance bisphenol A 3.3116393666
MESH:D007410 Intestinal Diseases Tretinoin 3.8117994277
MESH:D019586 Intracranial Hypertension Vitamin A 5.8815955940
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.088074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 10.0316580747
MESH:D007569 Jaw Abnormalities Tretinoin 10.0315992940 17551590
MESH:D007674 Kidney Diseases Acetaminophen 6.0115629191 12587719
MESH:D007674 Kidney Diseases sodium arsenite 6.0120008137
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 2.996582329
MESH:D007938 Leukemia Genistein 6.4618980019 17468513
MESH:D007938 Leukemia Tretinoin 6.4617143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.7316482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.9019850784 16294345 17596541
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 3.9016294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.1716935935 17339181 17506722 9834237 12679006 17361223 16766008 17368321 19029980 19075265 17301526 16891316 16140955 19035177 19225113 17294898 15748426 17217047 16331271 17649720 16823087 19642359 17712046 17107899 16788101
MESH:D017880 Limb Deformities, Congenital Tretinoin 8.579224671
MESH:D017880 Limb Deformities, Congenital Vitamin A 8.5716054864
MESH:D008103 Liver Cirrhosis Vitamin A 3.8916256175
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.219327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Genistein 5.0417823541
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 5.0412878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 5.0416248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental Vitamin A 5.0416248980
MESH:D008107 Liver Diseases Acetaminophen 4.3119460945 16610002 12969438 19784758 16611625 11587558 19014921 12587719
MESH:D008107 Liver Diseases Vitamin A 4.3116175620
MESH:D008108 Liver Diseases, Alcoholic Vitamin A 5.2016762690
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2617185352 16871587
MESH:D008113 Liver Neoplasms Pentachlorophenol 7.6810696769
MESH:D008113 Liver Neoplasms sodium arsenite 7.6815276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 7.6816984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 10.03598648 6587162 3712494 1399818
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 10.0312151625
MESH:D008114 Liver Neoplasms, Experimental Vitamin A 10.0317113696
MESH:D008171 Lung Diseases sodium arsenite 7.8419095001
MESH:D008171 Lung Diseases Vitamin A 7.8416863852
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.3217228818
MESH:D008175 Lung Neoplasms sodium arsenite 2.3116712894 17077188 17306315 15276417 19931552
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.3119555203 11884234
MESH:D008223 Lymphoma Pentachlorophenol 4.6312669308
MESH:D008325 Mammary Neoplasms, Experimental Genistein 2.9614578162 12929590
MESH:D008527 Medulloblastoma Tretinoin 2.7917453147
MESH:D008545 Melanoma sodium arsenite 3.3519082730 16487513
MESH:D008545 Melanoma Tretinoin 3.3516752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6119513568
MESH:D008591 Meningomyelocele Tretinoin 4.4716940565
MESH:D008881 Migraine Disorders Valproic Acid 3.2118803445 18765137
MESH:D009101 Multiple Myeloma Vitamin A 4.0716374440
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.068888407
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.4517596541
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 7.4517596541
MESH:D009203 Myocardial Infarction Genistein 2.8717141266
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0412213967
MESH:D015428 Myocardial Reperfusion Injury Genistein 3.6817141266
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.483581430
MESH:D009369 Neoplasms sodium arsenite 5.1511559025
MESH:D009369 Neoplasms Tretinoin 5.1516946489 16594593
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.7120056578
MESH:D018301 Neoplasms, Mesothelial Pentachlorophenol 6.7210696769
MESH:D009421 Nervous System Malformations bisphenol A 23.7811399458 16427766
MESH:D009421 Nervous System Malformations Genistein 23.7816427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 23.7814600291
MESH:D009421 Nervous System Malformations Tretinoin 23.789125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 22.976679447
MESH:D009436 Neural Tube Defects sodium arsenite 22.9712854658
MESH:D009436 Neural Tube Defects Tretinoin 22.979142499
MESH:D009436 Neural Tube Defects Valproic Acid 22.9716359493 8888407
MESH:D009436 Neural Tube Defects Vitamin A 22.9717400914
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8918514411
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.454026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.083988306
MESH:D010024 Osteoporosis Genistein 3.2719401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 4.1216169203
MESH:D010049 Ovarian Diseases bisphenol A 5.0411985600
MESH:D010051 Ovarian Neoplasms Genistein 7.9819005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 7.9817306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 7.9816936753
MESH:D010146 Pain Acetaminophen 6.6616870215
MESH:D010146 Pain Tretinoin 6.6616870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.4715976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7211578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.527296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3112520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.536228378
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5918163543
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 16.5610548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 16.5611118676 11222880 11896295 11399792
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 16.5620603192
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.2420887781
MESH:D011471 Prostatic Neoplasms bisphenol A 2.6316740699
MESH:D011471 Prostatic Neoplasms Genistein 2.6315256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.6316039940
MESH:D011507 Proteinuria Tretinoin 3.6416636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.3615861022 16919318
MESH:D019310 Pseudolymphoma Valproic Acid 4.6011422049 12752131
MESH:D011625 Pterygium Tretinoin 4.8416723453
MESH:D011629 Puberty, Precocious bisphenol A 4.8410548101
MESH:D012127 Respiratory Distress Syndrome, Newborn Vitamin A 5.8516877224
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8718990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.393692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 10.9716283617 16116481
MESH:D012208 Rhabdomyosarcoma Valproic Acid 10.9719155313
MESH:D012559 Schizophrenia marker/mechanism 17140601
MESH:D012559 Schizophrenia Valproic Acid 2.0715737665 19110320
MESH:D012640 Seizures Valproic Acid 2.751511512 17978042 11044598 14763951 3137016 16876388 15475178 11738929
MESH:D012871 Skin Diseases Vitamin A 3.3618709164
MESH:D012878 Skin Neoplasms sodium arsenite 9.5018572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.5016192470
MESH:D012878 Skin Neoplasms Tretinoin 9.5016467112
MESH:D013088 Spermatocele Ethinyl Estradiol 4.0016709447
MESH:D016135 Spinal Dysraphism sodium arsenite 9.6112854658
MESH:D016135 Spinal Dysraphism Valproic Acid 9.6119490988
MESH:D013160 Splenic Neoplasms Pentachlorophenol 6.3710696769
MESH:D013226 Status Epilepticus Valproic Acid 4.6012833885
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D019966 Substance-Related Disorders bisphenol A 4.0316045194 16684133
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9612697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 7.206582329 1399818 6587162 7505956 3712494
MESH:D013964 Thyroid Neoplasms Tretinoin 7.2017045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 3.8116051514
MESH:D014178 Translocation, Genetic Valproic Acid 5.3017262798
MESH:D014376 Tuberculosis Tretinoin 3.2416040207
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.573119515
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 5.128074119
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 5.1216712894 17306315 11723127 16452187
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.688888407
MESH:D014581 Urticaria Acetaminophen 3.0110982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 9.5011813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 9.5016129372
MESH:D014591 Uterine Diseases bisphenol A 5.0714652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3314692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.6716752155
MESH:D014652 Vascular Diseases sodium arsenite 4.4717056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5714671159 15869587
MESH:D014802 Vitamin A Deficiency Vitamin A 5.3116960172 16175781 16146918
MESH:D014820 Vitiligo Tretinoin 4.0916761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3115886252
MESH:D009396 Wilms Tumor Tretinoin 3.9916287080
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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